CN111948930A - Rotary sensor chip array disc and intelligent wearable watch using same - Google Patents
Rotary sensor chip array disc and intelligent wearable watch using same Download PDFInfo
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- CN111948930A CN111948930A CN202010918427.5A CN202010918427A CN111948930A CN 111948930 A CN111948930 A CN 111948930A CN 202010918427 A CN202010918427 A CN 202010918427A CN 111948930 A CN111948930 A CN 111948930A
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- G—PHYSICS
- G04—HOROLOGY
- G04B—MECHANICALLY-DRIVEN CLOCKS OR WATCHES; MECHANICAL PARTS OF CLOCKS OR WATCHES IN GENERAL; TIME PIECES USING THE POSITION OF THE SUN, MOON OR STARS
- G04B47/00—Time-pieces combined with other articles which do not interfere with the running or the time-keeping of the time-piece
- G04B47/06—Time-pieces combined with other articles which do not interfere with the running or the time-keeping of the time-piece with attached measuring instruments, e.g. pedometer, barometer, thermometer or compass
- G04B47/063—Time-pieces combined with other articles which do not interfere with the running or the time-keeping of the time-piece with attached measuring instruments, e.g. pedometer, barometer, thermometer or compass measuring physiological quantities, e.g. pedometers, heart-rate sensors, blood pressure gauges and the like
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Abstract
The invention provides a rotary sensor chip array disc and an intelligent wearable watch using the same, which can realize long-term stable monitoring of biochemical indexes through a brand-new structural design, and avoid frequent replacement and influence on use convenience.
Description
Technical Field
The invention relates to the technical field of biosensing, in particular to a rotary sensing chip array disc and an intelligent wearable watch using the same.
Background
With the progress of economic society, the demand of national people for active health is continuously increasing. The demand of people for health is not only disease diagnosis and treatment, but also disease improvement and disease improvement, and more attention is paid to disease prevention and good health condition.
At present, research around the active health field is highly active, innovative technologies and products are continuously emerging, wherein the research of wearable biosensors based on the body biochemistry and the real-time monitoring of physiological indexes also becomes a hot spot of advanced scientific and technological research at home and abroad, and the wearable biosensors can detect various health state identification indexes such as glucose, lactic acid, uric acid, amino acid, fatty acid and various ions (such as sodium, potassium, calcium and chlorine) in body fluid and establish the relation with related indexes of human health.
Wearable medical health equipment is the general name of equipment that is applied to sign detection, motion data statistics and health status with wearable technique and improves, possesses three major functions such as monitoring physiological index, record data, dynamic observation, and one of its key core technique is biosensor's construction, and is different with the physiological index such as traditional wearable equipment of motion only can detect blood pressure, pulse, and the wearable medical health equipment that adopts biosensor focuses on more reflecting the biochemical index of human deep health.
However, since the biological recognition substance in the biosensor is difficult to exist stably for a long time, and the biological recognition substance is difficult to inactivate after use and is difficult to be reused, it is difficult to realize long-term stable detection of the biochemical index, which greatly limits the industrial use of the biological recognition substance in the wearable device or POCT device, and therefore, the development of a wearable device or POCT device capable of performing biochemical index monitoring stably for a long time is a problem to be solved.
Technical scheme
The invention aims to solve the technical problem of providing a rotary sensing chip array disc and an intelligent wearable watch using the same, which can realize long-term stable monitoring of biochemical indexes through a brand-new structural design, avoid frequent replacement and influence on use convenience.
Based on the above, the invention provides a rotary sensing chip array disc, which comprises a substrate, a central control rotating shaft, a rotating disc, a sensing analysis chip monomer, a signal detection chip, a supporting plate and a micro sample inlet, wherein the central control rotating shaft and the rotating disc are fixed on the substrate.
The central control rotating shaft penetrates through a central hole of the rotating disc to provide power for the rotation of the rotating disc, the rotating speed of the rotating disc is controlled through a mechanical gear on the central control rotating shaft, the rotating speed is regulated and controlled through time correlation with the intelligent watch, and the timed transposition replacement of a single chip of the biosensor analysis chip array disc on the rotating disc is achieved.
The supporting plate is fixed above the rotating disc and penetrates through the central control rotating shaft, and the signal detection chip is fixed on the supporting plate.
Wherein, the number of the signal detection chips is 1-2.
Wherein, be provided with the trace sample inlet on signal detection chip, the trace sample inlet pastes the skin surface when the wrist-watch is worn and is used for gathering the body fluid.
Wherein, the biosensor analysis chip monomer array plate is evenly distributed on the rotating plate.
Wherein, the rotating disc is distributed with 2-24 biosensing analysis chips.
The biosensor analysis chip monomer is composed of a counter electrode and a working electrode modified by a recognition receptor.
The invention further provides an intelligent wearable sports bracelet or sports watch, which comprises the rotary sensing chip array disk.
Advantageous effects
According to the rotary type sensing chip array disc and the intelligent wearable watch using the same, provided by the invention, through a brand-new structural design, the long-term stable monitoring of biochemical indexes can be realized, frequent replacement is avoided, the use convenience is not influenced, and the problem that the intelligent wearable equipment cannot detect the biochemical indexes in real time for a long time is solved.
Drawings
FIG. 1 is a diagram illustrating an overall configuration of a sports watch according to the present invention;
FIG. 2 is a schematic diagram of a rotary sensor chip array disk according to the present invention.
Detailed Description
The invention provides a rotary sensing chip array disc which comprises a substrate, a central control rotating shaft, a rotating disc, a sensing analysis chip monomer, a signal detection chip, a supporting plate and a micro sample inlet, wherein the central control rotating shaft and the rotating disc are fixed on the substrate.
The central control rotating shaft penetrates through the central hole of the rotating disc to provide power for the rotation of the rotating disc, the rotating speed of the rotating disc is controlled through a mechanical gear on the central control rotating shaft, the rotating speed is regulated and controlled through time correlation with the intelligent watch, and the timing transposition replacement of a single chip of the biological sensing analysis chip array disc on the rotating disc is achieved.
The supporting plate is fixed above the rotating disc and penetrates through the central control rotating shaft, the signal detection chips are fixed on the supporting plate, the number of the signal detection chips is 1-2, preferably 2, the signal detection chips are used for detecting signal results of sensing analysis chip monomers, biological identification signals on the chips are converted into electric signals, and reading on wearable equipment is further realized through the current or potential detection module.
The signal detection chip is provided with a trace sample inlet, and the trace sample inlet is attached to the surface of the skin to be used for collecting body fluid when the watch is worn.
The biosensor analysis chip single array disk is uniformly distributed on the rotating disk, and 2-24 biosensor analysis chips can be distributed according to specific use requirements.
The biosensing analysis chip monomer is composed of a counter electrode and a working electrode modified by a recognition receptor, when the working electrode modified by the biosensing receptor is contacted with corresponding recognition biochemical molecules in sweat, biospecific recognition (such as catalytic reaction of enzyme and substrate or specific combination of antigen and antibody) can be carried out, and after the biospecific recognition is carried out, a transduction layer co-modified with the biosensing receptor on the surface of the electrode can convert biological signals into electric signals (current, resistance and potential change) or optical signals (luminescence change of a fluorescent probe) for collection of an integrated signal detection chip.
The signal detection chip is used for detecting the signal result of the sensing analysis chip monomer, digitally outputting the signal and converting the signal into a reading on the wearable device through algorithm software.
The chip array disk is used as an accessory of a wearable watch or a wearable bracelet.
The body fluid may be sweat, saliva, blood, etc., preferably sweat.
The recognition receptor, such as glucose oxidase, lactate oxidase, urate oxidase, amino acid oxidase, fatty acid decarboxylase, etc., is used for recognizing glucose, lactate, uric acid, amino acid, fatty acid and various ion (such as sodium, potassium, calcium, chlorine) indexes in human body fluid.
The electrode interface layer is made of carbon-based nano materials and can be graphene nanosheets, graphite nanosheets, graphene oxide nanosheets, graphite oxide nanosheets, large-area graphene sheets, Carbon Nanotubes (CNTs) and combinations thereof. The working electrode material can be gold, a carbon material electrode or the carbon nano composite material formed by patterning, and the counter electrode material is platinum or silver or a carbon paste electrode.
The invention further provides an intelligent wearable sports bracelet or sports watch, which comprises the rotary sensing chip array disk.
Sports bracelet or sports wrist-watch still include the watchcase, protection panel, the hou gai, the battery, the mainboard, the electronic screen, the watchcase passes through screw fixed connection with the hou gai, rotation type sensing chip array dish back-off is covered after, leave the space that corresponds with the micro-sampling hole on the chip array dish in the back lid bottom, be used for collecting the body fluid, the battery is located the top of chip array dish, be used for the power supply of sports bracelet or sports wrist-watch, the mainboard is located the battery top, the electronic screen is located the watchcase, rotation type sensing chip array dish wire connection is to on the mainboard, the mainboard wire is connected to the electronic screen, the realization shows the signal of telecommunication that rotation type sensing chip array dish acquireed on the electronic screen.
The biological sensing chip provided by the invention is inserted into the watch through the plug-and-play interface, and can be plugged and replaced at any time.
The following embodiments are described in detail to solve the technical problems by applying technical means to the present invention, and the implementation process of achieving the technical effects can be fully understood and implemented.
As shown in figure 1, the invention provides a rotary sensing chip array disk for detecting biochemical indexes of a human body in real time, which comprises a substrate 1, a central control rotating shaft 2, a rotating disk 3, a sensing analysis chip monomer 4, a signal detection chip 5, a supporting plate 6 and a micro sample inlet 7, wherein the central control rotating shaft 2 and the rotating disk 3 are fixed on the substrate 1.
The central control rotating shaft 2 penetrates through a central hole of the rotating disc to provide power for the rotation of the rotating disc, the rotating speed of the rotating disc is controlled through a mechanical gear 8 on the central control rotating shaft 2, the rotating speed is regulated and controlled through time correlation with the intelligent watch, and the timed transposition replacement of a single chip of the biosensor analysis chip array disc on the rotating disc is achieved. The supporting plate 6 is fixed above the rotating disc 3 and penetrates through the central control rotating shaft 2, and the signal detection chips 5 are fixed on the supporting plate 6 and are 2 in number. The signal detection chip 6 is provided with a trace sample inlet 7 which is attached to the surface of the skin to collect body fluid when the watch is worn. The body fluid can be sweat, saliva, blood and the like, preferably sweat, the biosensor analysis chip monomer 4 array disc is uniformly distributed on the rotating disc 3, and 2-12 biosensor analysis chips can be distributed according to specific use requirements.
The biosensing analysis chip monomer is composed of a counter electrode and a working electrode modified by a recognition receptor, when the working electrode modified by the biosensing receptor is contacted with corresponding recognition biochemical molecules in sweat, biospecific recognition (such as catalytic reaction of enzyme and substrate or specific combination of antigen and antibody) can be carried out, and after the biospecific recognition is carried out, a transduction layer co-modified with the biosensing receptor on the surface of the electrode can convert biological signals into electric signals (current, resistance and potential change) or optical signals (luminescence change of a fluorescent probe) for collection of an integrated signal detection chip.
The signal detection chip is used for detecting the signal result of the sensing analysis chip monomer, digitally outputting the signal and converting the signal into a reading on the wearable device through algorithm software.
As shown in FIG. 2, the intelligent wearable watch for detecting human body biochemical indexes in real time provided by the invention, which comprises a watchcase 9, a back cover 10, a battery 11, a mainboard 12, an electronic screen 13, the rotary sensing chip array disk 14 and a protection panel 15, wherein the watchcase 9 is fixedly connected with the back cover 10 through screws, the rotary sensing chip array disk 14 is reversely buckled on the back cover 10, a gap corresponding to the micro sampling hole on the chip array tray 14 is left at the bottom of the back cover 10 for collecting body fluid, the battery 11 is positioned above the chip array tray 14, the electronic watch is used for supplying power to the sports watch, the mainboard 12 is located above the battery 11, the electronic screen 13 is located in the watch case 9, the rotary sensing chip array disk 14 is connected to the mainboard 12 through a lead, the mainboard 12 is connected to the electronic screen 13 through a lead, and therefore electric signals acquired by the rotary sensing chip array disk are displayed on the electronic screen.
All of the above mentioned intellectual property rights are not intended to be restrictive to other forms of implementing the new and/or new products. Those skilled in the art will take advantage of this important information, and the foregoing will be modified to achieve similar performance. However, all modifications or alterations are based on the new products of the invention and belong to the reserved rights.
The foregoing is directed to preferred embodiments of the present invention, other and further embodiments of the invention may be devised without departing from the basic scope thereof, and the scope thereof is determined by the claims that follow. However, any simple modification, equivalent change and modification of the above embodiments according to the technical essence of the present invention are within the protection scope of the technical solution of the present invention.
Claims (10)
1. A rotary sensor chip array disk, comprising: the micro-sampling device comprises a substrate, a central control rotating shaft, a rotating disk, a sensing analysis chip monomer, a signal detection chip, a supporting plate and a micro-sampling port, wherein the central control rotating shaft and the rotating disk are fixed on the substrate.
2. The rotary sense die array disk of claim 1, wherein: the central control rotating shaft penetrates through the central hole of the rotating disc to provide power for the rotation of the rotating disc, the rotating speed of the rotating disc is controlled through a mechanical gear on the central control rotating shaft, the rotating speed is regulated and controlled through time correlation with the intelligent watch, and the timing transposition replacement of a single chip of the biological sensing analysis chip array disc on the rotating disc is achieved.
3. The rotary sense die array disk of claim 1 or 2, wherein: the supporting plate is fixed above the rotating disc and penetrates through the central control rotating shaft, and the signal detection chip is fixed on the supporting plate.
4. The rotary sense die array disk of claims 1 to 3, wherein: the number of the signal detection chips is 1-2.
5. The rotary sense die array disk of claims 1 to 4, wherein: the signal detection chip is provided with a trace sample inlet, and the trace sample inlet is attached to the surface of the skin to be used for collecting body fluid when the watch is worn.
6. The rotary sense die array disk of claims 1 to 5, wherein: the biosensor analysis chip monomer array discs are uniformly distributed on the rotating disc.
7. The rotary sense die array disk of claims 1 to 6, wherein: the rotating disc is distributed with 2-24 biosensing analysis chips.
8. The rotary sense die array disk of claims 1 to 7, wherein: the biosensor analysis chip monomer is composed of a counter electrode and a working electrode modified by a recognition receptor.
9. The utility model provides a wearable motion bracelet of intelligence which characterized in that: comprising the rotary sensor chip array disk of claims 1 to 8.
10. The utility model provides a wearable motion wrist-watch of intelligence which characterized in that: comprising the rotary sensor chip array disk of claims 1 to 8.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010918427.5A CN111948930B (en) | 2020-09-02 | 2020-09-02 | Rotary sensor chip array disc and intelligent wearable watch using same |
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| CN202010918427.5A CN111948930B (en) | 2020-09-02 | 2020-09-02 | Rotary sensor chip array disc and intelligent wearable watch using same |
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| CN111948930A true CN111948930A (en) | 2020-11-17 |
| CN111948930B CN111948930B (en) | 2021-12-21 |
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Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201594142U (en) * | 2009-12-04 | 2010-09-29 | 中国辐射防护研究院 | Automatic filter selecting device |
| CN103110431A (en) * | 2012-09-12 | 2013-05-22 | 中国科学院深圳先进技术研究院 | Noninvasive continuous blood pressure measurement device and method |
| CN103353713A (en) * | 2013-07-05 | 2013-10-16 | 昆山宏凌电子有限公司 | Electronic watch |
| US20140148669A1 (en) * | 2010-09-01 | 2014-05-29 | Javier Francisco Garcia Saban | Device For Continuous Measuring Of An Analyte |
| CN104159508A (en) * | 2012-01-04 | 2014-11-19 | 耐克创新有限合伙公司 | Athletic watch |
| WO2015120753A1 (en) * | 2014-02-12 | 2015-08-20 | 韩磊 | Electric vehicle battery pack replacement system consisting of computers, internet, multiple robots |
| CN105411595A (en) * | 2015-12-25 | 2016-03-23 | 杭州电子科技大学 | Wearable body surface physiological and biochemical parameter monitoring system |
| CN205672019U (en) * | 2016-05-05 | 2016-11-09 | 成都铅笔科技有限公司 | Intelligence wearable device |
| CN206089646U (en) * | 2016-09-18 | 2017-04-12 | 宁波博奥生物工程有限公司 | High flux multiplicity biochip system |
| CN206147272U (en) * | 2016-06-15 | 2017-05-03 | 金钱象网络科技（北京）有限公司 | Sign detects intelligent wrist -watch |
| CN107111342A (en) * | 2015-01-02 | 2017-08-29 | 三星电子株式会社 | Electronic equipment and its control method including rotary body |
| CN107479361A (en) * | 2017-08-28 | 2017-12-15 | 歌尔股份有限公司 | Intelligent watch and its heart rate detection method |
| WO2018100176A1 (en) * | 2016-12-02 | 2018-06-07 | Metemis Development | Cartridge for biochemical sensor |
| CN207946391U (en) * | 2018-03-30 | 2018-10-09 | 江西水利职业学院(江西省水利水电学校、江西省灌溉排水发展中心、江西省水利工程技师学院） | Wearable electrochemical sensor |
| CN109037519A (en) * | 2016-08-26 | 2018-12-18 | 赵琼 | A kind of apparatus for automatic change of battery |
| CN110057890A (en) * | 2019-03-26 | 2019-07-26 | 中国科学院苏州生物医学工程技术研究所 | A kind of hemostasis examination chip and electrochemical sensor |
| CN110186986A (en) * | 2019-06-21 | 2019-08-30 | 福建工程学院 | Electrochemical glucose sensor and its detection method without enzyme |
| CN210960664U (en) * | 2019-10-17 | 2020-07-10 | 上海博哈寿生物科技有限公司 | Wearable equipment of intelligence |
-
2020
- 2020-09-02 CN CN202010918427.5A patent/CN111948930B/en active Active
Patent Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201594142U (en) * | 2009-12-04 | 2010-09-29 | 中国辐射防护研究院 | Automatic filter selecting device |
| US20140148669A1 (en) * | 2010-09-01 | 2014-05-29 | Javier Francisco Garcia Saban | Device For Continuous Measuring Of An Analyte |
| CN104159508A (en) * | 2012-01-04 | 2014-11-19 | 耐克创新有限合伙公司 | Athletic watch |
| CN103110431A (en) * | 2012-09-12 | 2013-05-22 | 中国科学院深圳先进技术研究院 | Noninvasive continuous blood pressure measurement device and method |
| CN103353713A (en) * | 2013-07-05 | 2013-10-16 | 昆山宏凌电子有限公司 | Electronic watch |
| WO2015120753A1 (en) * | 2014-02-12 | 2015-08-20 | 韩磊 | Electric vehicle battery pack replacement system consisting of computers, internet, multiple robots |
| CN107111342A (en) * | 2015-01-02 | 2017-08-29 | 三星电子株式会社 | Electronic equipment and its control method including rotary body |
| CN105411595A (en) * | 2015-12-25 | 2016-03-23 | 杭州电子科技大学 | Wearable body surface physiological and biochemical parameter monitoring system |
| CN205672019U (en) * | 2016-05-05 | 2016-11-09 | 成都铅笔科技有限公司 | Intelligence wearable device |
| CN206147272U (en) * | 2016-06-15 | 2017-05-03 | 金钱象网络科技（北京）有限公司 | Sign detects intelligent wrist -watch |
| CN109037519A (en) * | 2016-08-26 | 2018-12-18 | 赵琼 | A kind of apparatus for automatic change of battery |
| CN206089646U (en) * | 2016-09-18 | 2017-04-12 | 宁波博奥生物工程有限公司 | High flux multiplicity biochip system |
| WO2018100176A1 (en) * | 2016-12-02 | 2018-06-07 | Metemis Development | Cartridge for biochemical sensor |
| CN107479361A (en) * | 2017-08-28 | 2017-12-15 | 歌尔股份有限公司 | Intelligent watch and its heart rate detection method |
| CN207946391U (en) * | 2018-03-30 | 2018-10-09 | 江西水利职业学院(江西省水利水电学校、江西省灌溉排水发展中心、江西省水利工程技师学院） | Wearable electrochemical sensor |
| CN110057890A (en) * | 2019-03-26 | 2019-07-26 | 中国科学院苏州生物医学工程技术研究所 | A kind of hemostasis examination chip and electrochemical sensor |
| CN110186986A (en) * | 2019-06-21 | 2019-08-30 | 福建工程学院 | Electrochemical glucose sensor and its detection method without enzyme |
| CN210960664U (en) * | 2019-10-17 | 2020-07-10 | 上海博哈寿生物科技有限公司 | Wearable equipment of intelligence |
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| CN111948930B (en) | 2021-12-21 |
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