CN1119113A - 复方癌复康胶囊及制备方法 - Google Patents
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Abstract
复方癌复康胶囊及其制备方法。本发明配方由人参、蛤壳、松萝、桃仁、苦杏仁、生南星、生半夏、珍珠母、珍珠、大黄、儿茶、金银花、木鳖子、琥珀、广藿香、沉香、黑芝麻、山豆根、白花蛇舌草、半枝莲、熊胆粉、干姜、大枣、蜈蚣二十四味加辅料(红粉、轻粉、雄黄)组成。珍珠、蜈蚣、熊胆粉分别炮制后粉碎成细粉，其余二十一味分别炮制后混合，烘干粉碎成细粉，加入上述粉末混匀，过筛、灭菌，加辅料混合分装胶囊。本发明可以防、治各种肿瘤，有效率为百分之九十。
Description
本发明属于抗肿瘤药品及药品的制备方法。
恶性肿瘤对人类的健康危害是严重的，目前治疗各和癌症的药物很多，但大部分西药毒副作用大，成本极高，一些药品只能适用于一种癌症，有局限性，治愈率低。
本发明的目地在于利用我国的中草药提供一种能够防治人体各部位实体肿瘤、能够该善癌症晚期病人生存质量的抗癌药品。
本发明的技术方案是从我国中草药中提纯有效的抗癌成分，强化中药的攻毒杀菌、活血化瘀、消坚散结的作用。本发明的配方及配比如下：人 参5.2～5.6％，蛤 壳5.2～5.6％，松 萝5.2～5.6％，桃 仁5.2～5.6％，苦杏仁5.2～5.6％，生南星5.2～5.6％，生半夏5.2～5.6％，珍珠母5.2～5.6％，珍 珠1.0～1.2％大 黄6.3～6.7％，儿 茶3.1～3.5％，金银花3.1～3.5％木鳖子7.0～7.4％，琥 珀2.0～2.4％，广藿香1.0～1.2％沉 香1.0～1.2％，黑芝麻5.2～5.6％，山豆根3.1～3.5％半枝莲3.1～3.5％，熊胆粉0.6～0.8％，干 姜1.7～1.9％大 枣3.1～3.5％，蜈 蚣1.0～1.2％，白花蛇舌草5.2～5.6％，辅料(红粉2.9％，轻粉1.8％，雄黄1.8％)6.3～6.7％
本发明对制备工艺有特殊的要求，珍珠、蜈蚣、熊胆粉分别炮制后粉碎成细粉，细度为760目以上，备用；其余各味分别炮制后混合烘干粉碎成细粉，细度为60目以上，加入珍珠粉、熊胆粉和蜈蚣粉混合均匀，再过筛，物理灭菌，最后加入辅料混合均匀，分装胶囊。
中医认为肿瘤是全身性疾病的局部反映，其内因是长期情志抑郁，正气虚弱引起机体阴阳平衡失调；外因是六淫外浸，感受邪毒及饮食不节(洁)等，从而发生气滞血瘀，湿聚痰结，邪毒壅踞等一系列病理变化，产生气、血、痰、食等病理产物，目积月累，这些病理产物相互交结，形成有形的肿物表现于机体某部，于是发生了肿瘤。根据上述理论本发明的方剂主要筛选了具有清热解毒、扶正去邪、益气养血、活血化瘀、软坚散结作用的药物组成，其中，人参大补元气，复脉固脱，补脾益肺，生津安神；枣肉补中益气，生精养血；黑芝麻补肝肾，润五脏而益精血，这三药合之则可增强体质，从而增强免疫功能达到防癌目地。方中的生南星、松萝、生半夏、白花蛇舌草具有很强的化痰散结、消肿去痞作用，佐以半枝莲、山豆根相辅，可以起到抑制肿瘤和达到治、抗癌的作用，白花蛇舌草可用于胃癌、食道癌和直肠癌等消化系统多种癌症，半枝莲可用于肝、肺、胃癌等。上药配伍可使治、抗肿瘤疗效俱增。松萝、儿茶、金银花具有抗菌生肌清热解毒作用。此三味药主要是防治肿瘤患者的合并细菌感染，使病灶减缩。桃仁、杏仁活血化瘀，蛤粉清热化痰、软坚散结、制酸止痛，琥珀活血散瘀安神，大黄泻热通肠、逐瘀解毒而弃，木鳖子散坚消肿、攻毒疗疮，这六味药综合则有软坚散结、活血化瘀、消肿止痛的功能。方中的蜈蚣除直接攻毒散结、通络止痛外，与生南星、生半夏配伍同用，可以毒攻毒，消除人体细胞中的“致癌基因产生的突变”。熊胆粉可清肝胆湿热而解毒，有燥湿收敛生肌的作用，对肝、肺、胃肿瘤可辅助抗癌药物发挥作用。珍珠母平肝潜阳，治头痛眩晕，作为辅助药物可减轻患者的有关症状。沉香、藿香、干姜有调合脾胃和止吐、止痛的功能，即可缓解胃肠症状的痛苦，又可促进食欲，干姜在方中又解生南星、生半夏之毒，回阳通脉。上述药物的功能使本发明能够达到抑制癌细胞的生长、扩散、转移的疗效，同时又能补益正气，增强机体的免疫力，增加单核巨噬细胞的吞噬能力，所以本发明对肝癌、肺癌、胃癌等各类肿瘤有良好的预防和治疗作用。经临床试验表明，本发明对前期病人可以治愈，对中晚期病人可以使疼痛减轻，可抑制病灶的发展，能使食欲增加，体力加强，提高病人的生存质量，延长生存期。本发明使用方便、安全，无毒性。本发明的有效率为百分之九十，是防、治、抗恶性肿瘤的特效药物。
下面给出本发明的实施例：
取人参15克、蛤壳15克、松萝15克、桃仁15克、苦杏仁15克、生南星15克、生半夏15克、珍珠母15克、珍珠3克、大黄18克、儿茶9克、金银花9克、木鳘子20克、琥珀6克、广藿香3克、沉香3克、黑芝麻15克、山豆根9克、半枝莲9克、熊胆粉2克、干姜5克、大枣9克、蜈蚣3克、白花蛇舌草15克、辅料18克(其中红粉8克、轻粉5克、雄黄5克)，共计276克。
先炮制药材：
1.桃仁：除去杂质，置沸水中，焯至外皮微皱时，捞入冷水中，等凉后取出，搓去外皮，晒干。再将晒干的桃仁置锅中，用文火炒至表面焦黄时，取出晾凉。
2.苦杏仁：除去杂质，置沸水中，焯至外皮微皱时，捞入冷水中，等凉后取出，搓去外皮，晒干。再将晒干的苦杏仁置锅中，用文火炒至微黄时，取出晾凉。
3.珍珠母：除去杂质，平摊于锅中，用武火煅烧至红透时，取出晾凉。
4.珍珠：珍珠用布包好，加豆腐二块(约二斤)与适量水共煮约2小时，取出，洗净，晾干，碾成极细粉。
5.大黄：取黄酒喷淋于黄片内，拌匀，盖严，稍润置锅中用文火炒至深褐色，取出晾干，每100克大黄用黄酒20克。
6.木鳖子：除去杂质置于锅中，用文火炒至表面黑褐色，取出晾凉扒去种皮，将种仁置于锅中，用文火炒至微褐色，取出晾凉。
7.大枣：取大枣除去杂质，洗净，去掉果核烘干即可。
其余各味均按国家药典中药材炮制项下进行炮制。
将珍珠、蜈蚣、熊胆粉粉碎成细粉(过60目以上的筛)备用，其余二十一味混合烘干，粉碎成细粉(过60目以上筛)后，加入上述粉末混合均匀，再过筛、物理法灭菌，加入辅料混合，分装胶囊，打光即可。
处方总量276克，烘干后重266克，粉碎后重256～258克，装0.25克胶囊，理论装量可制成1000粒。
Claims (2)
1.复方癌复康胶囊，其特征在于其配方组成如下：人 参5.2～5.6％，蛤 壳5.2～5.6％，松 萝5.2～5.6％，桃 仁5.2～5.6％，苦杏仁5.2～5.6％，生南星5.2～5.6％，生半夏5.2～5.6％，珍珠母5.2～5.6％，珍 珠1.0～1.2％大 黄6.3～6.7％，儿 茶3.1～3.5％，金银花3.1～3.5％木鳖子7.0～7.4％，琥 珀2.0～2.4％，广藿香1.0～1.2％沉 香1.0～1.2％，黑芝麻5.2～5.6％，山豆根3.1～3.5％半枝莲3.1～3.5％，熊胆粉0.6～0.8％，干 姜1.7～1.9％大 枣3.1～3.6％，蜈 蚣1.0～1.2％，白花蛇舌草5.2～5.6％，辅料(红粉2.9％，轻粉1.8％，雄黄1.8％)6.3～6.7％
2.复方癌复康胶囊的制作方法，其特征在于珍珠、蜈蚣、熊胆粉分别炮制后粉碎成细粉，细度为60目以上，备用；其余各味分别炮制后混合烘干粉碎成细粉，细度为60目以上，加入珍珠粉、熊胆粉和蜈蚣粉混合均匀，再过筛，物理灭菌，最后加入辅料混合均匀，分装胶囊。
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| CN 94116263 CN1119113A (zh) | 1994-09-22 | 1994-09-22 | 复方癌复康胶囊及制备方法 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058182C (zh) * | 1997-09-08 | 2000-11-08 | 刘强 | 抗癌丸 |
| CN1058882C (zh) * | 1996-09-24 | 2000-11-29 | 来春荣 | 一种治疗肿瘤的口服液及其制备方法 |
| US6723351B2 (en) | 1997-11-10 | 2004-04-20 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US6733792B1 (en) | 1998-04-24 | 2004-05-11 | Daopei Lu | Arsenic sulfide compounds and derivatives thereof for the treatment of malignancies |
| US6875451B2 (en) | 1997-10-15 | 2005-04-05 | Polarx Biopharmaceuticals Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| EP3281527A4 (en) * | 2015-08-28 | 2018-10-03 | Infinitus (China) Company Ltd. | Antimicrobial traditional chinese medicine composition, and preparation method and use thereof |
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1994
- 1994-09-22 CN CN 94116263 patent/CN1119113A/zh active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058882C (zh) * | 1996-09-24 | 2000-11-29 | 来春荣 | 一种治疗肿瘤的口服液及其制备方法 |
| CN1058182C (zh) * | 1997-09-08 | 2000-11-08 | 刘强 | 抗癌丸 |
| US6875451B2 (en) | 1997-10-15 | 2005-04-05 | Polarx Biopharmaceuticals Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| US7205001B2 (en) | 1997-10-15 | 2007-04-17 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| US7179493B2 (en) | 1997-10-15 | 2007-02-20 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| US7163703B2 (en) | 1997-10-15 | 2007-01-16 | Polarx Biopharmaceuticals, Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| US7132116B2 (en) | 1997-10-15 | 2006-11-07 | Polarx Biopharmaceuticals Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| US6770304B2 (en) | 1997-11-10 | 2004-08-03 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US6884439B2 (en) | 1997-11-10 | 2005-04-26 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US6982096B2 (en) | 1997-11-10 | 2006-01-03 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US6861076B2 (en) | 1997-11-10 | 2005-03-01 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US6855339B2 (en) | 1997-11-10 | 2005-02-15 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US6723351B2 (en) | 1997-11-10 | 2004-04-20 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US7879364B2 (en) | 1997-11-10 | 2011-02-01 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US8273379B2 (en) | 1997-11-10 | 2012-09-25 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| US7138147B2 (en) | 1998-04-24 | 2006-11-21 | Daopei Lu | Arsenic sulfide compounds and derivatives thereof for the treatment of malignancies |
| US6733792B1 (en) | 1998-04-24 | 2004-05-11 | Daopei Lu | Arsenic sulfide compounds and derivatives thereof for the treatment of malignancies |
| EP3281527A4 (en) * | 2015-08-28 | 2018-10-03 | Infinitus (China) Company Ltd. | Antimicrobial traditional chinese medicine composition, and preparation method and use thereof |
| US10321689B2 (en) | 2015-08-28 | 2019-06-18 | Infinitus (China) Company Ltd. | Antimicrobial traditional Chinese medicine composition, and preparation method and use thereof |
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