CN111905036A - Self-heating graphene health-care functional plaster - Google Patents

Self-heating graphene health-care functional plaster Download PDF

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CN111905036A
CN111905036A CN202010775102.6A CN202010775102A CN111905036A CN 111905036 A CN111905036 A CN 111905036A CN 202010775102 A CN202010775102 A CN 202010775102A CN 111905036 A CN111905036 A CN 111905036A
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skin
moistening
self
traditional chinese
chinese medicine
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苏庚洵
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared

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  • Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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Abstract

The invention relates to the field of traditional Chinese medicine treatment, in particular to a self-heating graphene health-care functional plaster. The plaster is sequentially distributed with a gauze-free adhesive layer (1), a self-heating layer (2), a graphene cloth layer (3) and a refined traditional Chinese medicine core layer (4) from bottom to top; also comprises a skin-moistening transdermal liquid bag (5) used cooperatively. The traditional Chinese medicine core layer (4) is a refined traditional Chinese medicine layer, and is a traditional Chinese medicine core prepared by refining rhizoma arisaematis, rhizoma corydalis, herba asari, semen Impatientis, herba Ephedrae, etc. by vacuum freeze-drying technology, and retains the biological activity of the medicine. Compared with the prior art, the invention adopting the technical scheme has the following beneficial effects: the product of the technology is simple and convenient to use, the emollient is dripped on the drug core to form a fresh paste before use, the efficacy of the ointment is instantly released to act on the affected part, and the problems of dryness and hardness of the ointment, loss of active ingredients of the medicine and unfavorable absorption of the efficacy of the medicine are solved. Self-heating promotes drug potency transdermal absorption, and far infrared rays can improve the pain tissue repair function and improve the curative effect.

Description

Self-heating graphene health-care functional plaster
Technical Field
The invention relates to the field of traditional Chinese medicine treatment, in particular to a self-heating graphene health-care functional plaster.
Background
With aging, at least about 80% of the elderly population over 65 years of age suffer from a chronic pain, with most elderly suffering from a variety of geriatric conditions. Oral administration brings about a plurality of side effects to the middle-aged and the elderly, so that the chronic pain trouble of the middle-aged and the elderly is solved, and the traditional Chinese medicine external treatment is a simple, convenient and effective method. The traditional Chinese medicine for warming channels, dredging collaterals, dispelling wind and removing dampness is selected, and the gauze-free bag is packed and then heated, fumigated and hot-compressed on the affected part. The hot fumigation helps the medicine to permeate into the affected part from the skin to achieve the purpose of treatment. In recent years, a self-heating pack is combined with a plaster patch for the convenience of patient use, so that the plaster patch has a self-heating function. However, the plaster is dry and hard, the active ingredients of the medicine are lost, and the efficacy of the medicine is not beneficial to skin absorption, and meanwhile, the plaster is not convenient to use and cannot achieve the treatment effect because the plaster is stuck on the affected part, the skin is not firm and is easy to fall off, and the like.
Graphene (Graphene) is a polymer made of carbon atoms in sp2The hybrid tracks form a hexagonal honeycomb lattice two-dimensional carbon nanomaterial.
The graphene has excellent optical, electrical and mechanical properties, has important application prospects in the aspects of materials science, micro-nano processing, energy, biomedicine, drug delivery and the like, and is considered to be a revolutionary material in the future.
Graphene is used to accelerate osteogenic differentiation of human mesenchymal stem cells, and is also used to fabricate biosensors of epitaxial graphene on silicon carbide. Meanwhile, the graphene can be used as a neural interface electrode without changing or damaging the performance, such as signal intensity or scar tissue formation. Due to the characteristics of flexibility, biocompatibility, conductivity and the like, the graphene electrode is much more stable in vivo than a tungsten or silicon electrode. The graphene oxide is very effective in inhibiting the growth of escherichia coli, and does not harm human cells.
Disclosure of Invention
The purpose of the invention is as follows: in order to provide a self-heating graphene plaster with a health care function, the specific purpose is to see a plurality of substantial technical effects of the specific implementation part.
In order to achieve the purpose, the invention adopts the following technical scheme:
the self-heating graphene health-care functional plaster is characterized in that a gauze-free adhesive tape layer (1), a self-heating layer (2), a graphene fabric layer (3) and a traditional Chinese medicine core layer (4) are sequentially distributed on the plaster from bottom to top; also comprises a skin-moistening transdermal liquid bag (5) which is matched with the skin-moistening transdermal liquid bag, and each layer is connected by medical hot melt adhesive.
The further technical scheme of the invention is that the traditional Chinese medicine core layer (4) is a refined traditional Chinese medicine layer, and the medicine core is prepared by refining rhizoma arisaematis, rhizoma corydalis, asarum, garden balsam seed, ephedra and other medicines by adopting a vacuum freeze-drying technology, so that the medicine activity is maintained.
The further technical proposal of the invention is that the skin-moistening transdermal liquid bag (5) is a separate liquid bag.
The further technical scheme of the invention is that the skin-moistening transdermal liquid packet (5) is a skin-moistening transdermal liquid packet (5) adhered to the traditional Chinese medicine core layer.
The further technical proposal of the invention is that the skin-moistening transdermal liquid bag (5) comprises an opening (6) at the mouth part facing to the Chinese medicinal core layer; the opening (6) can open the package of the skin moistening transdermal liquid bag (5) when being pressed or heated, so that the skin moistening liquid infiltrates the traditional Chinese medicine core layer from the skin moistening transdermal liquid bag (5).
The further technical scheme of the invention is that the side of the skin-moistening transdermal fluid pack (5) comprises a separating tearing membrane (7), and the skin-moistening transdermal fluid pack (5) can be separated by tearing and pulling the separating tearing membrane (7) by hands.
Compared with the prior art, the invention adopting the technical scheme has the following beneficial effects: the product of the technology is simple and convenient to use, the emollient is dripped on the drug core to form a fresh paste before use, the efficacy of the ointment is instantly released to act on the affected part, and the problems of dryness and hardness of the ointment, loss of active ingredients of the medicine and unfavorable absorption of the efficacy of the medicine are solved. Self-heating promotes drug potency transdermal absorption, and far infrared rays can improve the pain tissue repair function and improve the curative effect.
Drawings
To further illustrate the present invention, further description is provided below with reference to the accompanying drawings:
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a second embodiment of the present invention;
wherein: 1. a gauze-free rubberized fabric layer; 2. a self-heating layer; 3. a graphene cloth layer; 4. a Chinese medicinal core layer; 5. a skin-moisturizing transdermal pack; 6. an opening; 7. the tear film was separated.
Detailed Description
The present invention will be further illustrated with reference to the accompanying drawings and specific embodiments, which are to be understood as merely illustrative of the invention and not as limiting the scope of the invention. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", "top", "bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, as they may be fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The patent provides a plurality of parallel schemes, and different expressions belong to an improved scheme based on a basic scheme or a parallel scheme. Each solution has its own unique features.
The first embodiment is as follows: combine fig. 1 and fig. 2; the self-heating graphene health-care functional plaster is characterized in that a gauze-free adhesive tape layer (1), a self-heating layer (2), a graphene fabric layer (3) and a traditional Chinese medicine core layer (4) are sequentially distributed on the plaster from bottom to top; the layers are adhered and connected by medical hot melt adhesive. Also comprises a skin-moistening transdermal liquid bag (5) used cooperatively.
The technical scheme of the invention has the following substantial technical effects and the realization process: the prior art has the inconvenience of traditional Chinese medicine fumigation. The self-heating plaster is dry and hard, the active ingredients of the medicine are lost, the efficacy of the medicine is not beneficial to skin absorption, and meanwhile, the plaster is thickened, is not firmly adhered to the skin of an affected part and is easy to fall off, so that the ideal treatment effect cannot be achieved.
Has the advantages that:
1. the invention improves and designs the self-heating layer on the basis of the traditional fumigation external washing, so that the plaster keeps the self-heating function, and has the effects of warming and dredging channels and collaterals and promoting the absorption of medicines.
2. The refined traditional Chinese medicine core adopts a vacuum freeze-drying technology to maintain the activity of the medicine, and when the medicine is applied, the medicine core is mixed with the skin moistening transdermal agent to form a fresh paste, so that the biological activity of the medicine is ensured, and the problems that the plaster is not dry and hard for a long time, the active ingredients of the medicine are lost, and the medicine efficacy is not beneficial to absorption are solved.
3. The skin moistening transdermal agent has the effects of moistening skin, resisting allergy, strongly permeating and quickly relieving pain.
4. The biomass graphene far infrared rays can expand blood capillaries, promote blood circulation and increase the regeneration capacity of tissues, thereby playing a role in treating pain.
The three components are applied simultaneously, so that the synergistic and additive benefits are achieved, and the penetration of the medicinal efficacy components of the medicament is accelerated. The patient can feel the effect within 30 minutes, dredge microcirculation channels, improve the blood circulation of local tissues, remove the blood stasis in the deep part of the body, remove harmful substances in the tissues, promote the absorption of exudates in inflammatory parts, diminish inflammation and relieve pain. Thereby achieving the effect of recovering the body function.
The heating plaster structure sequentially comprises a gauze-free adhesive layer, a self-heating layer, a graphene cloth layer, a refined traditional Chinese medicine layer, a skin-moistening transdermal liquid bag and a temperature control patch. Namely, the moxibustion thermal therapy patch can also comprise a temperature control patch, wherein the temperature control patch refers to the current septal moxibustion thermal therapy patch; the temperature control paste is adhered and connected with the outside of the skin moistening transdermal liquid bag (5) by medical hot melt adhesive.
When in use, the skin moistening and skin penetration liquid is uniformly dripped on the refined freeze-dried powder drug core, the drug and the solution are fused to form a fresh paste, and the drug efficacy is instantly released to act on the affected part. By the aid of the heat of the self-heating bag, the effects of warming and dredging channels and collaterals, promoting blood circulation by removing blood stasis, and expelling wind and removing cold are achieved.
The biomass graphene generates far infrared rays, can promote blood circulation and increase the regeneration capacity of tissues, thereby playing a role in treating pain.
The product of the invention is a novel self-heating graphene health-care functional plaster, has a self-heating function, and when the seal is opened, the skin moistening and skin penetrating liquid is uniformly dripped on the refined traditional Chinese medicine freeze-dried powder medicine core, and the medicine is mixed with the solution to form a fresh paste which is applied to an affected part. By the aid of the heat of the self-heating bag, the effects of warming and dredging channels and collaterals, promoting blood circulation by removing blood stasis, and expelling wind and removing cold are achieved. Convenient use, firm adhesion and strong practicability and popularization and application.
This patent still has following outstanding advantage:
the active medicine is in the form of freeze-dried powder when not used and in the form of paste when used, and can maintain biological activity. The medicine efficacy is promoted to reach the affected part by the heat of the spontaneous heating bag.
Creatively, the above effects exist independently, and the combination of the above results can be completed by a set of structure.
Example two: as a further improvement or in a side-by-side or alternative independent solution, the skin-moistening transdermal liquid bag (5) is a separate liquid bag. The technical scheme of the invention has the following substantial technical effects and the realization process: in connection with fig. 1, a separate liquid pack can be used alone.
Example three: as a further improvement scheme or a parallel scheme or an alternative independent scheme, the skin moistening transdermal liquid bag 5 is the skin moistening transdermal liquid bag 5 adhered to the traditional Chinese medicine core layer.
Example four: as a further improvement scheme or a parallel scheme or an optional independent scheme, the skin-moistening transdermal liquid pack (5) comprises an opening (6) towards the direction of the traditional Chinese medicine core layer; the opening (6) can open the package of the skin moistening transdermal liquid bag (5) when being pressed or heated, so that the skin moistening liquid infiltrates the traditional Chinese medicine core layer from the skin moistening transdermal liquid bag (5). The technical scheme of the invention has the following substantial technical effects and the realization process: by compressed is meant that the liquid is squeezed out into the drug layer by hand pressure.
Example five: as a further improvement scheme or a side-by-side scheme or an alternative independent scheme, the side of the skin-moistening transdermal fluid bag (5) comprises a separating tearing film (7), and the skin-moistening transdermal fluid bag (5) can be separated by manually tearing and pulling the separating tearing film (7). The technical scheme of the invention has the following substantial technical effects and the realization process: after the liquid is used up, the skin-moistening transdermal liquid bag (5) is pulled and torn.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are intended to illustrate the principles of the invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, and the invention is to be limited to the embodiments described above.

Claims (8)

1. The self-heating graphene health-care functional plaster is characterized in that a gauze-free adhesive tape layer (1), a self-heating layer (2), a graphene fabric layer (3) and a traditional Chinese medicine core layer (4) are sequentially distributed on the plaster from bottom to top; all the layers are adhered and connected by medical hot melt adhesive; also comprises a skin-moistening transdermal liquid bag (5) used cooperatively.
2. The self-heating graphene health-care functional plaster patch according to claim 1, wherein the traditional Chinese medicine core layer (4) is a refined traditional Chinese medicine layer, and the traditional Chinese medicine core in the refined traditional Chinese medicine layer is subjected to vacuum freeze-drying technology to keep the activity of the medicine; the traditional Chinese medicine core comprises the following components: the medicine core is prepared by refining equal parts by weight of rhizoma arisaematis, rhizoma corydalis, asarum, garden balsam seed and ephedra through a vacuum freeze-drying technology.
3. The self-heating graphene health-care functional plaster patch according to claim 1, wherein the skin-moistening transdermal liquid bag (5) is a single liquid bag.
4. The self-heating graphene health-care functional plaster patch according to claim 1, wherein the skin-moistening transdermal liquid packet (5) is a skin-moistening transdermal liquid packet (5) adhered to a traditional Chinese medicine core layer.
5. The self-heating graphene health-care functional plaster patch according to claim 4, wherein the skin-moistening transdermal liquid packet (5) comprises an opening (6) at the mouth part facing the traditional Chinese medicine core layer; the opening (6) can open the package of the skin moistening transdermal liquid bag (5) when being pressed or heated, so that the skin moistening liquid infiltrates the traditional Chinese medicine core layer from the skin moistening transdermal liquid bag (5).
6. The self-heating graphene health-care functional plaster patch according to claim 4, wherein the side of the skin-moistening transdermal fluid bag (5) comprises a separating tearing membrane (7), and the skin-moistening transdermal fluid bag (5) can be separated by manually tearing and pulling the separating tearing membrane (7).
7. The self-heating graphene health-care functional plaster patch according to claim 3, wherein the skin moistening and skin penetrating fluid comprises the following components: turnip, borneol, azone and water.
8. The self-heating graphene health-care functional plaster patch according to claim 1, further comprising a temperature control patch located outside the skin moistening transdermal fluid bag (5), wherein the temperature control patch is adhered and connected to the outside of the skin moistening transdermal fluid bag (5) by medical hot melt adhesive.
CN202010775102.6A 2020-08-04 2020-08-04 Self-heating graphene health-care functional plaster Pending CN111905036A (en)

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CN107837308A (en) * 2017-11-16 2018-03-27 亚宝药业集团股份有限公司 A kind of externally applied transdermal patch
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CN209790601U (en) * 2019-01-15 2019-12-17 周启良 Health care plaster with spontaneous heating function
CN110664951A (en) * 2019-11-12 2020-01-10 河南煜和智能科技有限公司 Efficient physiotherapy patch added with graphene negative oxygen ions
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CN107837308A (en) * 2017-11-16 2018-03-27 亚宝药业集团股份有限公司 A kind of externally applied transdermal patch
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CN108785641A (en) * 2018-08-20 2018-11-13 皖南医学院 One kind can directly paste ataralgesia Warn uterus paste and its preparation method and application
CN111050430A (en) * 2018-10-12 2020-04-21 王伯文 Heating device based on graphene composite membrane, heating plaster and application
CN209790601U (en) * 2019-01-15 2019-12-17 周启良 Health care plaster with spontaneous heating function
CN110664951A (en) * 2019-11-12 2020-01-10 河南煜和智能科技有限公司 Efficient physiotherapy patch added with graphene negative oxygen ions

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* Cited by examiner, † Cited by third party
Title
李朝明，等: "脊痛灵巴布剂镇痛抗炎作用的实验研究", 《临床医学》 *

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Application publication date: 20201110