CN111888429A - Bone-knitting inflammation-diminishing pain-relieving ointment - Google Patents
Bone-knitting inflammation-diminishing pain-relieving ointment Download PDFInfo
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- CN111888429A CN111888429A CN202011022374.5A CN202011022374A CN111888429A CN 111888429 A CN111888429 A CN 111888429A CN 202011022374 A CN202011022374 A CN 202011022374A CN 111888429 A CN111888429 A CN 111888429A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention discloses a bone-knitting inflammation-diminishing pain-relieving ointment which is prepared from the following raw materials in parts by weight: white mulberry root-bark: gastrodia elata: soil insect: buckwheat = 400-: 400-500: 400-500: 400-500. The invention is elaborately developed according to the traditional Chinese medicine theory, the cortex mori radicis in the formula has antibacterial effect, and the cortex mori radicis decoction has strong inhibiting effect on staphylococcus aureus; has slight inhibition effect on typhoid bacillus and shigella flexneri. The rhizoma gastrodiae has the main functions that: stop endogenous wind and arrest convulsions. It is indicated for vertigo, dark eye, headache, wind-evil, headache, numbness of limbs, hemiplegia. The ground beetles break blood and remove stasis, reunion of fractured tendons and bones. Buckwheat can enrich intestines and stomach, increase strength, refresh spirit and remove filth of five internal organs. The traditional Chinese medicine composition has the advantages of compatibility of medicines, bring out the best in each other, body resistance strengthening, qi benefiting, blood nourishing, blood circulation promoting, blood stasis removing, heat clearing, detoxifying, long acting time, safety, no toxic or side effect, short treatment course, quick response and obvious treatment effect.
Description
Technical Field
The invention relates to a traditional Chinese medicine ointment, in particular to a bone-knitting inflammation-diminishing pain-relieving ointment.
Background
At present, methods for treating bone injuries include operations, acupuncture, massage, Du-moxibustion, traction, chiropractic manipulation, traditional Chinese medicine fumigation and the like, but the treatment methods of the operations, the massage and the chiropractic manipulation need good medical skills of doctors, and if the doctor does not operate the treatment methods, the body can be damaged. The methods of acupuncture, Du-moxibustion, traction, traditional Chinese medicine fumigation and the like have little risk, but the curative effect is not particularly good. The traditional Chinese medicine ointment has prominent manifestations in the field of treating bone fracture, but the traditional Chinese medicine ointment has long treatment course and slow effect.
Disclosure of Invention
The invention aims to provide a bone-knitting inflammation-diminishing pain-relieving ointment which not only has the effects of diminishing inflammation, relieving pain and knitting bones on bone fracture parts, but also can improve the immunity, and has short treatment course and quick response.
In order to solve the problems in the prior art, the invention adopts the technical scheme that:
the bone-knitting inflammation-diminishing pain-relieving ointment consists of the following raw materials in parts by weight: white mulberry root-bark: gastrodia elata: soil insect: buckwheat = 400-: 400-500: 400-500: 400-500.
The bone-knitting inflammation-diminishing pain-relieving ointment is prepared from the following raw materials in parts by weight: white mulberry root-bark: gastrodia elata: soil insect: buckwheat = 450: 450: 450: 450.
the invention has the advantages that:
the invention is elaborately developed according to the traditional Chinese medicine theory, the cortex mori radicis in the formula has an antibacterial effect, the cortex mori radicis decoction has a strong inhibition effect on staphylococcus aureus, and the cortex mori radicis decoction also has a slight inhibition effect on typhoid bacillus and shigella flexneri. The mulberry bark furan A has stronger bacteriostatic activity on staphylococcus aureus and mycobacterium. Cyclosporin also has antifungal effect. The acidic substance contained in cortex Mori can affect cyclooxygenase in blood platelet, thereby inhibiting biosynthesis of TBX2, or inhibiting production of 12-HETE, and affect blood platelet aggregation by changing metabolism of arachidonic acid. Cortex Mori is treated repeatedly with petroleum ether, ethanol, acetic anhydride, water, acetic acid, ethyl ester, etc., and the obtained yellow powder is administered to mice for intravenous injection, with LD50 of 32.7 mg/kg. The mice are not killed by the gastric lavage or the intraperitoneal injection of 10g/kg or the intravenous injection of 5g/kg of the n-butyl alcohol extract or the aqueous extract. No adverse effect is found on experimental animals when the alcohol extract is administrated in a large dose or a plurality of small doses. The rhizoma gastrodiae has the main functions that: stop endogenous wind and arrest convulsions. It is indicated for vertigo, dark eye, headache, wind-evil, headache, numbness of limbs, hemiplegia. Rhizoma Gastrodiae polysaccharide has effects of enhancing nonspecific immunity and cellular immunity of organism. The wingless cockroach has the main functions of breaking blood and removing stasis, and reuniting tendons and bones: amenorrhea due to blood stasis, abdominal mass; traumatic blood stasis and swelling; fracture of bones and muscles. Buckwheat can enrich intestines and stomach, increase strength, refresh spirit and remove filth of five internal organs. The traditional Chinese medicine composition has the advantages of compatibility of medicines, bring out the best in each other, body resistance strengthening, qi benefiting, blood nourishing, blood circulation promoting, blood stasis removing, heat clearing, detoxifying, long acting time, safety, no toxic or side effect, short treatment course, quick response and obvious treatment effect.
Clinical data:
case 1: a50-year-old female, who fell down while walking, had the elbow joint landed, and was diagnosed as: olecranal fracture. The affected part is cleaned, the plaster is pasted on the affected part, 10g of active ingredients are used for 1 pasting for 3 days, 5 pasting courses of treatment are carried out, the pain symptom disappears after the plaster is used for 10 pasting, and the affected part is cured after 2 months.
Case 2: when a 33-year-old male is angry, a left punch is used for hitting a room door, the far end of the fifth metacarpal bone is fractured, the pain and swelling feeling of the fractured part disappears after the plaster 6 is used, and the fracture is healed after 2 months.
Case 3, 28 year old male collided with the tree when riding a motorcycle, was diagnosed as scaphoid fracture and lunar dislocation with pain and deformation in the left wrist, and after application of the plaster 10, the pain and swelling of the thumb root disappeared and healed after 2 months.
Case 4: when a 57-year-old male sprains the left ankle joint and fractures the far end of the left fibula when walking, the pain and swelling feeling of the fractured part disappears after the plaster 6 is used for sticking, and the fracture is healed after 2 months.
Case 5: a63-year-old female suffers from pain and swelling of the left hip joint and obvious tenderness due to hydrops on the road surface. After the plaster is used for 10 times, the pain and swelling feel disappear, and the plaster can be cured after 2 months.
The ointment has the advantages of obvious curative effect, no toxic or side effect, short treatment course, quick response and convenient use, does not cause the skin of a patient to be burst even if the ointment is applied for a long time, and is suitable for patients with joint injuries such as various traumatic injuries, fractures (after open fracture and comminuted fracture operations), bone fracture and gall, injured tendons, injured bones and the like. Detailed Description
Example 1:
the bone-knitting inflammation-diminishing pain-relieving ointment consists of the following raw materials in parts by weight: 400 parts of cortex mori radicis, 500 parts of rhizoma gastrodiae, 500 parts of ground beetle and 500 parts of buckwheat.
The preparation method of the bone-knitting inflammation-diminishing pain-relieving ointment comprises the following steps: mixing the white mulberry root-bark, the gastrodia elata, the ground beetle and the buckwheat in parts by weight, grinding into fine powder, and mixing the raw materials in parts by weight according to a ratio of 1: 1, adding clear water, stirring uniformly, and spreading on a blank plaster cloth of the medical plaster for molding.
Example 2:
the bone-knitting inflammation-diminishing pain-relieving ointment consists of the following raw materials in parts by weight: 500 parts of cortex mori radicis, 400 parts of rhizoma gastrodiae, 400 parts of ground beetle and 400 parts of buckwheat. The preparation method of the ointment for setting bone, diminishing inflammation and relieving pain is the same as that of example 1.
Example 3:
the bone-knitting inflammation-diminishing pain-relieving plaster is characterized by comprising the following raw materials in parts by weight: 450 parts of cortex mori radicis, 450 parts of rhizoma gastrodiae, 450 parts of ground beetle and 450 parts of buckwheat. The preparation method of the ointment for setting bone, diminishing inflammation and relieving pain is the same as that of example 1.
Claims (2)
1. The bone-knitting inflammation-diminishing pain-relieving plaster is characterized by comprising the following raw materials in parts by weight: white mulberry root-bark: gastrodia elata: soil insect: buckwheat = 400-: 400-500: 400-500: 400-500.
2. The bone-knitting inflammation-diminishing pain-relieving plaster as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: white mulberry root-bark: gastrodia elata: soil insect: buckwheat = 450: 450: 450: 450.
Priority Applications (1)
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CN202011022374.5A CN111888429A (en) | 2020-09-25 | 2020-09-25 | Bone-knitting inflammation-diminishing pain-relieving ointment |
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CN202011022374.5A CN111888429A (en) | 2020-09-25 | 2020-09-25 | Bone-knitting inflammation-diminishing pain-relieving ointment |
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CN202011022374.5A Withdrawn CN111888429A (en) | 2020-09-25 | 2020-09-25 | Bone-knitting inflammation-diminishing pain-relieving ointment |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114869975A (en) * | 2022-04-07 | 2022-08-09 | 大连大学附属中山医院 | Traditional Chinese medicine preparation for treating bone wound blood stasis swelling and pain and preparation method thereof |
-
2020
- 2020-09-25 CN CN202011022374.5A patent/CN111888429A/en not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114869975A (en) * | 2022-04-07 | 2022-08-09 | 大连大学附属中山医院 | Traditional Chinese medicine preparation for treating bone wound blood stasis swelling and pain and preparation method thereof |
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Application publication date: 20201106 |