CN111876323A - Virus sampling, storing and detecting composite tube and using method thereof - Google Patents
Virus sampling, storing and detecting composite tube and using method thereof Download PDFInfo
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- CN111876323A CN111876323A CN202010876079.XA CN202010876079A CN111876323A CN 111876323 A CN111876323 A CN 111876323A CN 202010876079 A CN202010876079 A CN 202010876079A CN 111876323 A CN111876323 A CN 111876323A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/04—Seals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/11—Filling or emptying of cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0325—Cells for testing reactions, e.g. containing reagents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7756—Sensor type
- G01N2021/7759—Dipstick; Test strip
Abstract
The invention discloses a virus preservation and detection composite tube and a use method thereof. The composite pipe includes: the device comprises a pipe body, an upper cover and a lower cover, wherein a main cavity, an exchange cavity and a detection cavity which are communicated with an opening at the upper end of the pipe body are separately arranged in the pipe body, and the main cavity is communicated with the detection cavity through the exchange cavity; the lower cover is provided with a sealing element extending into the exchange cavity, and the lower cover is rotated to drive the sealing element to rotate in the exchange cavity, so that the exchange cavity communicated with the main cavity and the detection cavity is sealed or communicated. The invention has simple and practical structure and simple operation, can reduce the operation links of detection and save the detection cost. The invention can not only realize on-site sampling and on-site rapid detection, but also realize separate sampling and centralized detection, and simultaneously, the main cavity and the detection cavity are relatively sealed, so that the condition of cross contamination can not occur.
Description
The technical field is as follows:
the invention relates to the technical field of virus preservation test tube products, in particular to a virus preservation and detection composite tube and a use method thereof.
Background art:
at present, in the process of collecting and detecting some viruses, an independent virus sampling tube or a test tube is used for sampling and then is sealed, and then a detection reagent card or a special instrument is used for detection in a special laboratory. In addition, the detected sample of the detection method needs to be transferred among a sampling tube, a detection reagent card or a detection instrument, and the sample is not in a sealed state in the process, so that secondary transmission of viruses or air pollution is very likely to be caused, and the danger is high. Aiming at the defects, the invention creatively provides a composite detection tube which integrates virus sampling, sample storage and detection.
In view of the above situation, the present inventors have made improvements and have proposed the following technical solutions.
The invention content is as follows:
the invention aims to overcome the defects of the prior art and provide a virus sampling, storing and detecting composite tube which is used for storing, collecting and detecting virus samples.
In order to solve the technical problems, the invention adopts the following technical scheme: a virus sampling, storing and detecting composite tube comprises: the device comprises a pipe body, an upper cover and a lower cover which are respectively arranged on an upper end opening and a lower end opening of the pipe body, wherein a main cavity body communicated with an opening at the upper end of the pipe body, an exchange cavity body and a detection cavity body are separately arranged in the pipe body; the lower cover is provided with a sealing element extending into the exchange cavity, and the lower cover is rotated to drive the sealing element to rotate in the exchange cavity, so that the exchange cavity communicated with the main cavity and the detection cavity is sealed or communicated.
Furthermore, in the above technical scheme, the inner wall of the lower cover is formed with the fixture block, the outer wall of the pipe body is provided with the annular flange corresponding to the fixture block, and the lower cover is connected with the pipe body by the fastening connection of the fixture block and the annular flange.
Furthermore, in the above technical solution, the lower cover is fixedly connected with a protection brace, a positioning mechanism is formed between the protection brace and the pipe body, and the pipe body and the lower cover are relatively fixed by the positioning mechanism.
Further, in the above technical solution, the positioning mechanism includes: the positioning groove is arranged on the protection brace, the positioning block is arranged on the pipe body, and the pipe body and the lower cover are kept relatively fixed through the matching of the positioning groove and the positioning block.
Furthermore, in the above technical solution, a cutting groove is formed at a connection portion of the protection pulling strip and the lower cover, the protection pulling strip has an end portion extending to the outside, and the end portion is pulled by an external force to separate the protection pulling strip from the lower cover along the cutting groove.
Furthermore, among the above-mentioned technical scheme, the lower cover on the shaping have an arrow point, the shaping has a positioning groove who corresponds with the arrow point on the outer wall of body, after rotating the certain angle of lower cover, the arrow point falls into positioning groove, makes lower cover and body keep relatively fixed.
Furthermore, in the above technical solution, a separation frame is formed in the exchange cavity, the sealing member has a sealing plate corresponding to the separation frame, when the sealing plate and the separation frame are at the same angle, the exchange cavity is sealed and isolated by the separation frame and the sealing plate into a left space and a right space, wherein the left space is communicated with the main cavity, and the right space is communicated with the detection cavity.
Furthermore, in the above technical solution, a partition is disposed between the main cavity and the exchange space, and a plurality of through holes are disposed on the partition.
Furthermore, in the above technical scheme, a label space is provided in the detection cavity and arranged along the inner wall of the tube body, and a test strip is provided in the label space.
The invention also provides a use method of the virus sampling, storing and detecting composite tube, and the method adopts the following technical scheme. The use method of the composite pipe comprises the following steps: firstly, injecting virus preservation liquid into a main cavity in advance, adding an acquired detection sample into a tube body of the composite tube through an upper end opening, and sealing the upper end opening of the tube body through an upper cover, wherein at the moment, the detection sample is mixed with the virus preservation liquid in the main cavity, and meanwhile, a sealing element seals and separates the exchange cavity, so that the main cavity cannot be communicated with the detection cavity; secondly, destroying a positioning mechanism on the lower cover, enabling the lower cover to rotate relatively to the pipe body, and driving the sealing element to rotate in the exchange cavity by rotating the lower cover, wherein the sealing element does not seal and separate the exchange cavity any more in the rotating process, the main cavity and the detection cavity are communicated through the exchange cavity, so that a sample enters the detection cavity, and after rotating for a certain angle, the sealing element seals and separates the exchange cavity again, and the main cavity and the detection cavity are sealed and isolated; and thirdly, enabling a mixed liquid of the detection sample and the virus preservation liquid to enter a detection cavity, arranging a test strip in the detection cavity, enabling the mixed liquid to infiltrate the test strip to generate corresponding reaction, enabling the test strip to generate corresponding change, and enabling a user to observe the change of the test strip through the tube body, thereby determining a detection result.
Compared with the prior art, the method has the following advantages: the invention has simple and practical structure and simple operation, can reduce the operation links of detection and save the detection cost. The invention not only can carry out on-site sampling and on-site rapid detection, but also can carry out separated sampling and centralized detection. Since the sample is then detected in a sealed condition, there is no risk of a second transmission occurring. Is suitable for large-scale rapid screening of infectious diseases, and can be applied to customs, airports and schools. Trading markets, etc. Meanwhile, the sample with positive detection result of the product can be reviewed. Meanwhile, the main cavity and the detection cavity are relatively sealed, so that the condition of cross contamination cannot occur.
Description of the drawings:
FIG. 1 is a perspective view of the present invention;
FIG. 2 is a transverse cross-sectional view of the present invention;
FIG. 3 is a longitudinal cross-sectional view of the present invention;
FIG. 4 is an exploded perspective view of the present invention;
FIG. 5 is a perspective view of the lower opening of the tube of the present invention;
fig. 6 is a perspective view of the lower cap of the tube of the present invention.
The specific implementation mode is as follows:
the invention is further illustrated below with reference to specific embodiments and the accompanying drawings.
As shown in fig. 1 to 6, the present invention discloses a virus sampling, storing and detecting composite tube, which comprises: the pipe comprises a pipe body 1, an upper cover 2 and a lower cover 3, wherein the upper cover 2 and the lower cover 3 are respectively arranged on the upper end and the lower end of the pipe body 1.
The tube body 1 is made of transparent materials, for example, a glass tube or a plastic tube can be used. The inner cavity of the tube body 1 is provided with a main cavity 11, an exchange cavity 12 and a detection cavity 13 in a separated mode. Wherein the upper end of the main cavity 11 is communicated with the upper end opening of the tube body 1, and the lower end of the main cavity 11 is communicated with the exchange cavity 12. The exchange cavity 12 is located at the lower end opening of the tube body 1, and the main cavity 11 and the detection cavity 13 can be communicated through the exchange cavity 12.
Since the main chamber 11 needs to be filled with the virus-retaining liquid in advance, the space of the main chamber 11 is large. Referring to fig. 2, the upper half and one side space of the lower half of the inner cavity of the tube body 1 are used as the main cavity 11. Referring to fig. 6, a partition 110 is disposed between the main chamber 11 and the exchanging chamber 12, a plurality of through holes 111 are disposed on the partition 110, and the main chamber 11 is communicated with the exchanging chamber 12 through the through holes 111.
The exchange cavity 12 is located below the main cavity 11 and the test cavity 13, and the exchange cavity 12 is simultaneously communicated with the main cavity 11 and the test cavity 13. A separation frame 120 is formed within the exchange chamber 12. The separating frame 120 is located at the middle position of the exchanging cavity 12, and the exchanging cavity 12 can be separated into a left space 1201 and a right space 1202 along the plane where the separating frame 120 is located, wherein the left space 1201 is communicated with the main cavity 11, and the right space 1202 is communicated with the detection cavity 13.
The upper cover 2 is in threaded sealing connection with an opening at the upper end of the pipe body 1; the lower cover 3 can be rotatably arranged at the lower end opening of the tube body 1. The connection mode of the lower cover 3 and the pipe body 1 is as follows:
an annular flange 14 is arranged on the outer wall of the pipe body 1. The inner wall of lower cover 3 shape have the fixture block 32 that corresponds with annular flange 14, the inner wall evenly distributed of lower cover 3 has a plurality of fixture blocks 32 in this embodiment, be connected the realization of lower cover 3 and body 1 through the buckle of fixture block 32 and annular flange 14.
If the clamping blocks 32 are only connected with the annular flange 14 in a clamping manner, the pipe body 1 and the lower cover 3 can still rotate relatively, and in order to ensure that the pipe body 1 and the lower cover 3 can be positioned and cannot rotate relatively, the pipe body is positioned by the protection pull strip 4.
In this embodiment, the protection stay 4 is integrally formed with the lower cover 3, and the protection stay 4 is fixedly connected to the upper edge of the lower cover 3. The protection brace 4 forms a closed or semi-closed ring shape, a positioning mechanism is formed between the protection brace 4 and the tube body 1, and the tube body 1 and the lower cover 3 are kept relatively fixed and can not rotate relatively through the positioning mechanism.
As shown in fig. 1 and 4, the positioning mechanism includes: the positioning groove 42 arranged on the protection brace 4 and the positioning block 15 arranged on the tube body 1 keep the tube body 1 and the lower cover 3 relatively fixed and can not rotate relatively through the matching of the positioning groove 42 and the positioning block 15.
When the lower cover 3 needs to be rotated, the protection brace 4 needs to be broken, so that the positioning mechanism which keeps the relative fixation between the tube body 1 and the lower cover 3 is broken. As shown in fig. 3, a cut groove 40 is formed at the connection of the protection bar 4 and the lower cover 3, and the protection bar 4 has an end 41 extending to the outside, and the protection bar 4 is separated from the lower cover 3 along the cut groove 40 by pulling the end 41 by an external force. The cut groove 40 is designed to facilitate the separation of the protective pull-strip 4 from the lower cover 3, but other similar designs are also possible, for example, the cut groove 40 is designed to be connected at a plurality of points, and the protective pull-strip 4 can be separated from the lower cover 3 by pulling the end portion 41 with external force to break the connection at the points during use.
The lower cover 3 is provided with a sealing member 31 extending into the exchanging cavity 12, and the lower cover 3 is rotated to drive the sealing member 31 to rotate in the exchanging cavity 12, so that the exchanging cavity 12 communicating the main cavity 11 and the detecting cavity 13 is sealed or communicated. The sealing member 31 has a sealing plate 310 corresponding to the separating frame 120, and when the sealing plate 310 and the separating frame 120 are at the same angle, the left space 1201 and the right space 1202 of the exchanging cavity 12 are relatively sealed and isolated by the cooperation of the separating frame 120 and the sealing plate 310, so that the main cavity 11 communicated with the left space 1201 and the detection cavity 13 communicated with the right space 1202 are relatively sealed and isolated.
Referring to fig. 4, a sealing support plate 311 is formed on the inner surface of the lower cover 3, and a layer of silicone material is coated on the surface of the sealing support plate 311 of the lower cover 3 by injection molding, so as to form the sealing plate 310.
Referring to fig. 2 and 5, the detection chamber 13 has a label space 131 along the inner wall of the tube 1, and the label space 131 is also communicated with the exchange chamber 12. A test strip 5 is provided in the label space 131. The test strip 5 is arranged in the label space 131 and can be positioned to prevent the position from moving freely.
In addition, in order to ensure the angle of rotating the lower cover 3, an arrow 34 is formed on the lower cover 3, a positioning slot 16 corresponding to the arrow 34 is formed on the outer wall of the tube body 1, and after the lower cover 3 is rotated for a certain angle, the arrow 34 falls into the positioning slot 16, so that the lower cover 3 and the tube body 1 are relatively fixed. Specifically, the following method is adopted in the embodiment:
when the protection bar 4 is in the original state without being damaged, the seal 31 seals and separates the exchange cavity 12, the main cavity 11 and the detection cavity 13 cannot be communicated, and the position of the arrow 34 and the position of the positioning card slot 16 are just in a straight line in the original state.
After the protection brace 4 is damaged, the positioning mechanism between the tube body 1 and the lower cover 3 is damaged, the lower cover 3 is rotated by 180 degrees, the arrow 34 just falls into the positioning clamping groove 16, and the lower cover 3 is positioned with the tube body 1 through the cooperation of the arrow 34 and the positioning clamping groove 16. At this time, after the sealing plate 310 rotates 180 ° at the same time, the left space 1201 and the right space 1202 of the exchanging cavity 12 are sealed and isolated relatively by the cooperation of the separating frame 120 and the sealing plate 310 under the same angle state with the separating frame 120, so that the main cavity 11 communicating with the left space 1201 and the detection cavity 13 communicating with the right space 1202 are sealed and isolated relatively again.
As shown in fig. 4, the vertical positioning card slot 16 includes a first positioning card 161 and a second positioning card 162 formed on the surface of the tube 1, and a distance between the first positioning card 161 and the second positioning card 162 is used as a groove for accommodating the arrow 34. For the convenience of rotation, the first positioning block 161 is formed with a guide slope toward the rotation direction of the lower cover 3, and the arrow 34 can smoothly pass over the first positioning block 161 by the guide slope, so as to fall into the groove formed in front of the first positioning block 161 and the second positioning block 162.
The first positioning block 161 and the second positioning block 162 may also be used as a positioning mechanism for keeping the pipe body 1 and the lower cover 3 relatively fixed. As shown in fig. 6, positioning grooves 421 and 422 corresponding to the first positioning block 161 and the second positioning block 162 may be formed on the protection bar 4.
The use method of the composite pipe comprises the following steps:
first step, the virus preservation liquid has been injected into in advance in the main cavity 11, and the detection sample that will gather adds in body 1 of this compound pipe through the upper end opening to it is sealed with body 1 upper end opening through upper cover 2, at this moment, the virus preservation liquid mixture in detection sample and the main cavity 11, simultaneously, sealing member 31 will exchange cavity 12 sealed separation, makes main cavity 11 and the unable intercommunication of detection cavity 13.
In the second step, the positioning mechanism on the lower cover 3 is broken, i.e. the end 41 is pulled by external force, so that the protection pulling strip 4 is separated from the lower cover 3 along the cutting groove 40. Thus, the lower cover 3 loses the positioning mechanism and can rotate relatively to the tube body 1. The lower cover 3 is rotated to drive the sealing element 31 to rotate in the exchange cavity 12, the exchange cavity 12 is not sealed and separated by the sealing element 31 in the rotating process, the main cavity 11 and the detection cavity 13 are communicated through the exchange cavity, and the mixed liquid of the detection sample and the virus preservation liquid can enter the detection cavity 13 through the exchange cavity. After a certain angle of rotation (for example, 180 ° of rotation as described above), the seal 31 again seals the exchange chamber 12, leaving the main chamber 11 sealed from the detection chamber 13.
Thirdly, the mixed liquid of the detection sample and the virus preservation solution enters the detection cavity 13, the lower cover 3 is kept to stand for a certain time (for example, 15 minutes) in a downward direction, the mixed liquid of the detection sample and the virus preservation solution is made to be fully infiltrated with the test strip 5 in the detection cavity 13, a corresponding reaction is generated after the test strip 5, the test strip 5 is made to generate a corresponding change, and a user can observe the change of the test strip 5 through the tube body 1, so that the detection result is determined.
When the second step is performed, the lower cover 3 is rotated, and after the arrow 34 rotates the positioning slot 16, the arrow points to the label space 131 where the test strip 5 is arranged.
The invention has simple and practical structure and simple operation, can reduce the operation links of detection and save the detection cost. The invention not only can carry out on-site sampling and on-site rapid detection, but also can carry out separated sampling and centralized detection. Since the sample is then detected in a sealed condition, there is no risk of a second transmission occurring. Is suitable for large-scale rapid screening of infectious diseases, and can be applied to customs, airports and schools. Trading markets, etc. Meanwhile, the sample with positive detection result of the product can be reviewed. Meanwhile, the main cavity and the detection cavity are relatively sealed, so that the condition of cross contamination cannot occur.
It should be understood that the above description is only exemplary of the present invention, and is not intended to limit the scope of the present invention, which is defined by the appended claims.
Claims (10)
1. A virus sampling, storing and detecting composite tube comprises: body (1), install respectively at body (1) upper and lower both ends open-ended upper cover (2) and lower cover (3), its characterized in that:
the inner cavity of the tube body (1) is provided with a main cavity (11), an exchange cavity (12) and a detection cavity (13) which are communicated with an opening at the upper end of the tube body (1) in a separated manner, wherein the main cavity (11) is communicated with the detection cavity (13) through the exchange cavity (12);
the lower cover (3) is provided with a sealing piece (31) extending into the exchange cavity (12), and the lower cover (3) is rotated to drive the sealing piece (31) to rotate in the exchange cavity (12), so that the exchange cavity (12) communicated with the main cavity (11) and the detection cavity (13) is sealed or communicated.
2. The virus sampling, storing and detecting composite tube of claim 1, wherein: the inner wall shaping of lower cover (3) have fixture block (32), body (1) outer wall on be provided with annular flange (14) that correspond with fixture block (32), be connected the realization lower cover (3) and body (1) through the buckle of fixture block (32) and annular flange (14).
3. The virus sampling, storing and detecting composite tube of claim 1, wherein: the protective device is characterized in that a protective brace (4) is fixedly connected to the lower cover (3), a positioning mechanism is formed between the protective brace (4) and the pipe body (1), and the pipe body (1) and the lower cover (3) are kept relatively fixed through the positioning mechanism.
4. The virus sampling, storing and detecting composite tube of claim 3, wherein: the positioning mechanism comprises: the positioning groove (42) is arranged on the protection brace (4), the positioning block (15) is arranged on the pipe body (1), and the pipe body (1) and the lower cover (3) are kept relatively fixed through the matching of the positioning groove (42) and the positioning block (15).
5. The virus sampling, storing and detecting composite tube of claim 3, wherein: the connection part of the protection brace (4) and the lower cover (3) is provided with a cutting groove (40), the protection brace (4) is provided with an end part (41) extending to the outside, and the end part (41) is pulled by external force to separate the protection brace (4) from the lower cover (3) along the cutting groove (40).
6. The virus sampling, storing and detecting composite tube of claim 1, wherein: an arrow (34) is formed on the lower cover (3), a positioning clamping groove (16) corresponding to the arrow (34) is formed on the outer wall of the tube body (1), and after the lower cover (3) is rotated for a certain angle, the arrow (34) falls into the positioning clamping groove (16), so that the lower cover (3) and the tube body (1) are kept relatively fixed.
7. The virus sampling, storing and detecting composite tube according to any one of claims 1 to 6, wherein: a separation frame (120) is formed in the exchange cavity (12), the sealing element (31) is provided with a sealing plate (310) corresponding to the separation frame (120), when the sealing plate (310) and the separation frame (120) are in the same angle state, the exchange cavity (12) is sealed and separated into a left space (1201) and a right space (1202) by the separation frame (120) and the sealing plate (310), wherein the left space (1201) is communicated with the main cavity (11), and the right space (1202) is communicated with the detection cavity (13).
8. The virus sampling, storing and detecting composite tube of claim 7, wherein: a partition plate (110) is arranged between the main cavity (11) and the exchange space (12), and a plurality of through holes (111) are formed in the partition plate (110).
9. The virus sampling, storing and detecting composite tube of claim 7, wherein: the detection cavity (13) is internally provided with a label space (131) arranged along the inner wall of the tube body (1), and the label space (131) is internally provided with a test strip (5).
10. The virus sampling, storing and detecting composite tube of claim 1, wherein: the use method of the composite pipe comprises the following steps:
firstly, virus preservation liquid is injected into a main cavity (11) in advance, a collected detection sample is added into a tube body (1) of the composite tube through an upper end opening, the upper end opening of the tube body (1) is sealed through an upper cover (2), at the moment, the detection sample is mixed with the virus preservation liquid in the main cavity (11), and meanwhile, a sealing element (31) seals and separates an exchange cavity (12) to ensure that the main cavity (11) cannot be communicated with a detection cavity (13);
secondly, destroying a positioning mechanism on the lower cover (3), enabling the lower cover (3) to rotate relatively to the pipe body (1), so that the lower cover (3) is rotated to drive the sealing element (31) to rotate in the exchange cavity (12), the sealing element (31) does not seal and separate the exchange cavity (12) in the rotating process, the main cavity (11) is communicated with the detection cavity (13) through the exchange cavity, a sample enters the detection cavity, and after the lower cover is rotated for a certain angle, the sealing element (31) seals and separates the exchange cavity (12) again, so that the main cavity (11) and the detection cavity (13) form sealed separation;
and thirdly, the mixed liquid of the detection sample and the virus preservation solution enters the detection cavity (13), a test strip (5) is arranged in the detection cavity (13), the test strip (5) is soaked by the mixed liquid to generate corresponding reaction, the test strip (5) generates corresponding change, and a user can observe the change of the test strip (5) through the tube body (1), so that the detection result is determined.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010876079.XA CN111876323A (en) | 2020-08-25 | 2020-08-25 | Virus sampling, storing and detecting composite tube and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114113595A (en) * | 2021-11-29 | 2022-03-01 | 厦门宝太生物科技股份有限公司 | Virus extraction and storage integrated detection tube and application method thereof |
| CN115267175A (en) * | 2022-07-05 | 2022-11-01 | 杭州莱和生物技术有限公司 | Integrated medical detector |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114113595A (en) * | 2021-11-29 | 2022-03-01 | 厦门宝太生物科技股份有限公司 | Virus extraction and storage integrated detection tube and application method thereof |
| CN114113595B (en) * | 2021-11-29 | 2022-05-20 | 厦门宝太生物科技股份有限公司 | Virus extraction and storage integrated detection tube and application method thereof |
| WO2023092904A1 (en) * | 2021-11-29 | 2023-06-01 | 厦门宝太生物科技股份有限公司 | Virus extraction and preservation integrated detection tube and application method thereof |
| CN115267175A (en) * | 2022-07-05 | 2022-11-01 | 杭州莱和生物技术有限公司 | Integrated medical detector |
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