CN111870794A - Medicine carrying guide wire - Google Patents
Medicine carrying guide wire Download PDFInfo
- Publication number
- CN111870794A CN111870794A CN202010708805.7A CN202010708805A CN111870794A CN 111870794 A CN111870794 A CN 111870794A CN 202010708805 A CN202010708805 A CN 202010708805A CN 111870794 A CN111870794 A CN 111870794A
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- far
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- mandrel
- guide wire
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22079—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/091—Guide wires having a lumen for drug delivery or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention relates to the technical field of guide wires for interventional operations, in particular to a drug-loaded guide wire. The drug-loaded guide wire comprises a far-end mandrel, a guide wire rod body connected to one end of the far-end mandrel and a far-end round cap connected with the other end of the far-end mandrel; the far-end mandrel is a reducing shaft body, and the inner diameter size of the far-end mandrel is gradually reduced from the guide wire rod body to the far-end round cap, wherein one end of the far-end mandrel connected with the guide wire rod body is a large-diameter end, and one end of the far-end mandrel connected with the far-end round cap is a small-diameter end; the radius of the large-diameter end is 1-5 times of that of the small-diameter end; the far-end mandrel is provided with a drug loading area and a body area, the drug loading area is close to the small-diameter end, and the length of the drug loading area is less than or equal to 1/2 of the length of the far-end mandrel; the medicine carrying area is provided with a plurality of gradually-changed grooves with one large end and one small end, and the depth and the width of each gradually-changed groove are gradually changed; and the far-end mandrel is provided with a variable-pitch and variable-diameter elastic material.
Description
Technical Field
The invention relates to the technical field of guide wires for interventional operations, in particular to a drug-loaded guide wire.
Background
Cerebrovascular infarction, also known as ischemic stroke, refers to a serious consequence of brain blood supply insufficiency caused by the stenosis or occlusion of cerebral blood supply arteries including carotid artery and vertebral artery, which can lead to brain tissue necrosis, or directly lead to death of patients. The recanalization of blood vessels is the key to treat ischemic stroke, and the current main treatment methods comprise drug thrombolysis and mechanical thrombus removal aiming at the vascular occlusion, and the current main treatment methods comprise balloon dilatation, stent implantation and the like aiming at vascular stenosis.
At present, the drug thrombolysis is generally performed by intravenous injection by adopting medicines such as alteplase, urokinase and the like, so that the thrombus is dissolved, and the purpose of recanalization of blood vessels is achieved; in recent years, research on the treatment effect of arterial injection alteplase, urohormone and other thrombolytic drugs on ischemic stroke is also related, and a large number of related results show that the effect of arterial injection of alteplase, urohormone and other drugs on treating ischemic stroke is not obviously different from that of intravenous injection.
The current mechanical embolectomy mainly refers to stent embolectomy and suction embolectomy. Mechanical embolectomy, an emerging neuro-interventional procedure, has developed rapidly in recent years and has gained wide acceptance due to its high recanalization rate and good prognosis. The guide wire is one of basic medical instruments of interventional operations, is widely applied to stent embolectomy, and mainly has the main functions of firstly reaching an occlusion part and penetrating thrombus to be positioned at the far end of the thrombus to establish a path for a micro catheter and a embolectomy stent. In another suction embolus operation, the guide wire is mainly used for entering a blood vessel of a human body in advance and reaching an embolus position to establish a path for a suction catheter.
For balloon dilatation and stent implantation, the guide wire is mainly used for entering a human blood vessel to reach a narrow part in advance to establish a path for a balloon catheter and a stent delivery catheter. At present, in order to treat vascular stenosis and inhibit vascular restenosis, medical devices such as balloons and stents can be sprayed with drugs such as paclitaxel or rapamycin.
The conventional guide wire variable-pitch reducing spring part is generally designed in an equal diameter mode, so that the guide wire is not favorable for passing through a tortuous blood vessel or a narrow part to reach a target position, the passing performance of the guide wire is reduced to a certain extent, a doctor is required to apply larger pushing force, and the occurrence probability of adverse events such as blood vessel perforation, plaque falling off at the narrow part and the like is increased. When the guide wire is used for stent embolectomy, the diameter of the far end of the guide wire is the same as that of the rod body, the contact area between the round cap at the far end of the guide wire and thrombus is large, and the pressure is small under the condition of a certain pushing force, so that the thrombus is difficult to smoothly penetrate into the thrombus, and the thrombus is easy to displace; after the guide wire penetrates into the thrombus, the thrombus can be embedded into the distal end of the guide wire in a short time, when the guide wire is withdrawn, the thrombus can be broken, and the thrombus can escape into the deep part of the blood vessel along with blood after being broken, so that unpredictable risks can be brought to a patient.
Disclosure of Invention
In order to solve the technical problems, the first aspect of the invention provides a drug-carrying guide wire, the guide wire variable-pitch reducing spring is in a reducing design, the diameter of the guide wire variable-pitch reducing spring is gradually reduced from near to far, and the integral appearance of the variable-pitch reducing spring is in a circular truncated cone shape, so that the guide wire can more easily pass through a tortuous blood vessel or a narrow part, the required pushing force is small, the passing performance of the guide wire is improved, and the occurrence probability of adverse events such as blood vessel perforation, narrow part plaque falling and the like is reduced.
The diameter of the guide wire variable-pitch reducing spring is gradually reduced from near to far, so that the diameter of a circular cap at the far end of the guide wire is smaller, when the guide wire is used for stent embolectomy, the circular cap at the far end is in contact with thrombus in a blood vessel, the pressure is higher under the same pushing force, and the guide wire is easier to penetrate into the thrombus, so that the risk of displacement of the thrombus is avoided;
the spring part of seal wire distal end, spring wire winding surface and the inside seal wire dabber surface of spring wire winding are provided with and carry the medicine groove, through loading alteplase, urokinase or other medicines that can dissolve the thrombus fast, make the seal wire penetrate behind the thrombus under the effect of medicine in the inside tunnel form through-hole that forms of thrombus, prevent thrombus embedding seal wire distal end, thereby caused the broken risk of thrombus when having avoided the seal wire to withdraw from, and because of the effect of medicine, change in the inside great through-hole that forms of thrombus, be suitable for the entering and passing of taking a bolt operation with relevant pipe.
The spring part at the far end of the guide wire, the surface of the spring winding wire and the surface of the guide wire mandrel in the spring winding wire are provided with medicine carrying grooves, and paclitaxel, rapamycin or other medicines capable of treating vascular stenosis and inhibiting vascular restenosis are loaded, so that the guide wire has better trafficability when passing through and reaching the vascular stenosis part, and can also be used for pretreatment of subsequent operations such as balloon dilatation, stent implantation and the like.
In a preferred embodiment, the drug-loaded guide wire comprises a distal mandrel 1, a guide wire rod body 2 connected to one end of the distal mandrel 1, and a distal round cap 3 connected to the other end of the distal mandrel 1; the far-end mandrel 1 is a reducing mandrel body, and the inner diameter size of the far-end mandrel 1 gradually decreases from the guide wire rod body 2 to the far-end round cap 3, wherein one end of the far-end mandrel 1 connected with the guide wire rod body 2 is a large-diameter end 11, and one end of the far-end mandrel 1 connected with the far-end round cap 3 is a small-diameter end 12; the radius of the large-diameter end 11 is 1-5 times of the radius R of the small-diameter end 12; the distal mandrel 1 is provided with a drug loading region 13 and a body region 14, the drug loading region 13 is close to the small-diameter end 11, and the length of the drug loading region is less than or equal to 1/2 of the length of the distal mandrel 1; a plurality of gradual-change grooves 15 with a large end and a small end are arranged on the medicine carrying area 13, and the depth and the width of each gradual-change groove 15 are in a gradual change type; the far-end mandrel 1 is provided with a variable-pitch and variable-diameter elastic material, and the variable-pitch and variable-diameter elastic material is gradually reduced from the guide wire rod body 2 to the far-end round cap 3.
In some embodiments, the distal end cap 3, the distal end mandrel 1, and the guidewire shaft body 2 are a unitary structure and can be made by grinding, casting, or other processes.
In a preferred embodiment, the variable pitch and variable diameter elastic material is a variable pitch and variable diameter spring 16, and the overall appearance of the variable pitch and variable diameter spring 16 is in a truncated cone shape.
In a preferred embodiment, the pitch of the pitch-variable diameter spring 16 decreases in an arithmetic progression from the guide wire rod body 2 to the distal end round cap 3, and the pitch diameter of the spring ring of the pitch-variable diameter spring 16 decreases in an arithmetic progression from the guide wire rod body 2 to the distal end round cap 3.
In a preferred embodiment, the outer surface of the variable pitch spring 16 is provided with an arc-shaped groove 17.
In some embodiments, the arc-shaped groove 17 may be discontinuous, or may be composed of a plurality of parallel spiral drug-loading grooves.
In a preferred embodiment, the arc-shaped grooves 17 are arranged intermittently or continuously.
In a preferred embodiment, the arc-shaped grooves 17 are continuously distributed in a variable diameter spiral manner along the rotation direction of the spring ring.
In a preferred embodiment, the angle α between the line connecting the two slot edges of the arc-shaped groove 17 to the slot bottom is less than 180 degrees, more preferably less than 90 degrees.
In a preferred embodiment, the number of the gradual change grooves 15 is 3-8.
In a preferred or optional embodiment, the number of the gradual change grooves 15 is 4-8; more preferably 4 to 6, and for example, 3, 4, 5, 6, 7, or 8.
In a preferred embodiment, the gradual groove 15 extends to and through the small diameter end, and the depth and width of the gradual groove 15 gradually decrease from the distal dome to the guidewire shaft body 2.
In a preferred embodiment, the diameter of the bottom of the distal end round cap 3 is equal to the diameter of the top of the variable pitch reducing spring 16, and both are smaller than the diameter of the guide wire rod body 2; in this case, the guide wire 2 can be made to pass through a tortuous blood vessel or a stenotic portion of the blood vessel more easily, and the guide wire can be made to penetrate into thrombus more easily.
In a preferred embodiment, the pitch-variable diameter-variable spring 16 is made of any one or more of nickel-titanium alloy, stainless steel, platinum, gold, platinum-tungsten alloy and platinum-iridium alloy; generally, when the material is used in medical fluoroscopy equipment, the material plays a role of developing in a human body, and the developing effect of the far end of the guide wire under the radiation can be improved.
Has the advantages that:
1. the diameter of the variable-pitch reducing spring 16 is gradually reduced from near to far, so that the capability of the guide wire passing through a tortuous blood vessel or a narrow part of the blood vessel is improved;
2. the diameter of the circular cap 3 at the far end of the guide wire is smaller, so that the guide wire is easier to penetrate thrombus when being used for thrombus extraction operation, and the thrombus displacement is prevented.
3. The wire winding surface of the variable-pitch reducing spring 16 and the surface of the far-end mandrel 1 are provided with arc-shaped grooves 17, and the capability of the guide wire passing through stenosis lesion can be further improved by loading rapamycin, paclitaxel and other medicines for treating vascular stenosis and inhibiting vascular restenosis, and the guide wire can also be used as pretreatment of balloon expansion and stent implantation, so that the success rate of surgery is improved.
4. The wire winding surface of the variable-pitch reducing spring 16 and the surface of the far-end mandrel are provided with arc-shaped grooves 17, thrombus can be prevented from being embedded into the far end of the guide wire by loading rapid thrombolytic drugs such as alteplase, the risk of thrombus breakage caused by withdrawal of the guide wire is avoided, tunnel-shaped through holes are formed inside thrombus, and other instruments such as a catheter can conveniently pass through the thrombus.
5. Be provided with the big little gradual change recess 15 of one end of a plurality of one end on the medicine carrying district 13, and the arc recess is cross arrangement, because the pitch of the variable pitch reducing spring 16 who corresponds the medicine carrying district is very little, the more intensive department of pitch cooperation width and the bigger gradual change recess 15 of degree of depth, the great department of pitch then plays the effect of supporting the former cap 3 of distal end as this district 14, guarantees to be the same with the increase drug loading when the medicine that loads, can realize different effects when loading the medicine difference.
6. The radian of the arc-shaped groove 17 is larger than 180 degrees, arc transition is formed at the notch, and the smaller the blockage is received under the same pushing force, so that the pressure intensity is higher, and the guide wire is easier to penetrate into thrombus, thereby avoiding the risk of displacement of the thrombus; in addition, the medicine carrying is slowly released in the pushing process, more irregular tunnel-shaped through holes are formed in the thrombus under the matching of the crossed grooves, the thrombus can be prevented from being embedded into the distal end of the guide wire, and the risk of thrombus breakage caused by withdrawal of the guide wire is avoided.
Drawings
In order to more clearly illustrate the technical solution of the present invention, the drawings used in the embodiments will be briefly described below, the drawings described below are only some embodiments of the present invention, and it is obvious to those skilled in the art that other drawings can be obtained based on the drawings without creative efforts.
Fig. 1 is a schematic structural view of a drug-loaded guidewire according to example 1 of the present invention;
fig. 2 is a partial schematic view of a drug-loaded guidewire of example 1 of the present invention;
FIG. 3 is a schematic structural view of a distal mandrel according to example 1 of the present invention;
FIG. 4 is a schematic sectional view of a small diameter end in example 1 of the present invention;
the numbering in the figure is as follows:
1. a distal mandrel; 2. a guidewire rod body; 3. a distal end round cap; 11. a large diameter end; 12. a small diameter end; 13. a drug loading area; 14. a body region; 15. a gradual change groove; 16. a variable pitch and diameter spring; 17. an arc-shaped groove.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
The technical features of the technical solution provided by the present invention are further clearly and completely described below with reference to specific embodiments.
Example 1
As shown in fig. 1, 2 and 3, fig. 1 is a sectional view of fig. 3, and fig. 2 is an expanded view before folding; the embodiment 1 of the invention provides a drug-loaded guide wire, which comprises a distal mandrel 1, a guide wire rod body 2 connected to one end of the distal mandrel 1, and a distal round cap 3 connected to the other end of the distal mandrel 1; the far-end mandrel 1 is a reducing mandrel body, and the inner diameter size of the far-end mandrel 1 gradually decreases from the guide wire rod body 2 to the far-end round cap 3, wherein one end of the far-end mandrel 1 connected with the guide wire rod body 2 is a large-diameter end 11, and one end of the far-end mandrel 1 connected with the far-end round cap 3 is a small-diameter end 12; the radius of the large-diameter end 11 is 2 times of the radius R of the small-diameter end 12; the distal mandrel 1 is provided with a drug loading region 13 and a body region 14, wherein the drug loading region 13 is close to the small-diameter end 11 and has the length of 1/3 the length of the distal mandrel; a plurality of gradual-change grooves 15 with a large end and a small end are arranged on the medicine carrying area 13, and the depth and the width of each gradual-change groove 15 are in a gradual change type; the far-end mandrel 1 is provided with a variable-pitch and variable-diameter elastic material, and the variable-pitch and variable-diameter elastic material is gradually reduced from the guide wire rod body 2 to the far-end round cap 3.
The variable-pitch and variable-diameter elastic material is a variable-pitch and variable-diameter spring 16, and the overall appearance of the variable-pitch and variable-diameter spring 16 is in a truncated cone shape. The pitch of the variable pitch reducing spring 16 decreases progressively in an arithmetic progression in the direction from the guide wire rod body 2 to the far-end round cap 3, and the pitch diameter of the spring ring of the variable pitch reducing spring 16 decreases progressively in an arithmetic progression in the direction from the guide wire rod body 2 to the far-end round cap 3. And an arc-shaped groove 17 is formed in the outer surface of the spring ring of the variable-pitch and variable-diameter spring 16.
The arc-shaped grooves 17 are continuously distributed in a variable-diameter spiral manner along the rotation direction of the spring ring. The angle alpha of the connecting line from the two notch edges of the arc-shaped groove 17 to the groove bottom is smaller than 90 degrees.
The number of the gradual change grooves 17 is 4. The gradual change groove 15 extends to the small-diameter end 12 and penetrates through the small-diameter end 12, and the depth and the width of the gradual change groove 15 are gradually reduced from the far-end round cap 3 to the guide wire rod body 2.
The diameter of the bottom of the far-end round cap 3 is equal to the diameter of the top of the variable-pitch reducing spring 16, and the diameters of the bottom and the top are smaller than the diameter of the guide wire rod body 2. The pitch-variable diameter-variable spring 16 is made of nickel-titanium alloy.
Claims (10)
1. A drug-loaded guide wire is characterized by comprising a far-end mandrel, a guide wire rod body connected to one end of the far-end mandrel, and a far-end round cap connected with the other end of the far-end mandrel; the far-end mandrel is a reducing shaft body, and the inner diameter size of the far-end mandrel is gradually reduced from the guide wire rod body to the far-end round cap, wherein one end of the far-end mandrel connected with the guide wire rod body is a large-diameter end, and one end of the far-end mandrel connected with the far-end round cap is a small-diameter end; the radius of the large-diameter end is 1-5 times of that of the small-diameter end; the far-end mandrel is provided with a drug loading area and a body area, the drug loading area is close to the small-diameter end, and the length of the drug loading area is less than or equal to 1/2 of the length of the far-end mandrel; the medicine carrying area is provided with a plurality of gradually-changed grooves with one large end and one small end, and the depth and the width of each gradually-changed groove are gradually changed; the far-end mandrel is provided with a variable-pitch and variable-diameter elastic material, and the variable-pitch and variable-diameter elastic material is gradually reduced from the guide wire rod body to the far-end round cap.
2. The drug-loaded guidewire of claim 1, wherein the variable-pitch variable-diameter elastic material is a variable-pitch variable-diameter spring, and the overall appearance of the variable-pitch variable-diameter spring is in the shape of a truncated cone.
3. The medicated guidewire of claim 2, wherein the pitch of the pitch varying spring decreases in an arithmetic progression from the guidewire shaft to the distal end cap, and the pitch of the spring ring of the pitch varying spring decreases in an arithmetic progression from the guidewire shaft to the distal end cap.
4. The drug-loaded guidewire of claim 3, wherein the spring ring of the pitch-variable spring is provided with an arcuate groove on an outer surface thereof.
5. The medicated guidewire of claim 4, wherein the arcuate groove is discontinuous or continuous.
6. The drug-loaded guidewire of claim 4, wherein the arcuate grooves are arranged in a variable diameter spiral pattern along the rotational direction of the spring ring.
7. The drug-loaded guidewire of any one of claims 1-6, wherein the number of the gradual-change grooves is 3-8.
8. The medicated guidewire of claim 7, wherein the tapered groove extends to and through the small diameter end, the tapered groove having a depth and width that decreases in a direction from the distal end dome to the guidewire shaft body.
9. The medicated guidewire of claim 8, wherein the bottom diameter of the distal end cap is equal to the top diameter of the pitch varying spring and is less than the diameter of the guidewire shaft.
10. The drug-loaded guidewire of claim 8, wherein the pitch-variable diameter spring is made of one or more of nickel-titanium alloy, stainless steel, platinum, gold, platinum-tungsten alloy and platinum-iridium alloy.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202010708805.7A CN111870794A (en) | 2020-07-22 | 2020-07-22 | Medicine carrying guide wire |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202010708805.7A CN111870794A (en) | 2020-07-22 | 2020-07-22 | Medicine carrying guide wire |
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CN111870794A true CN111870794A (en) | 2020-11-03 |
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CN202010708805.7A Withdrawn CN111870794A (en) | 2020-07-22 | 2020-07-22 | Medicine carrying guide wire |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022228145A1 (en) * | 2021-04-26 | 2022-11-03 | 上海申淇医疗科技有限公司 | Medical device |
CN116077808A (en) * | 2023-02-07 | 2023-05-09 | 康湃医疗科技(苏州)有限公司 | Medicine carrying towing device |
-
2020
- 2020-07-22 CN CN202010708805.7A patent/CN111870794A/en not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022228145A1 (en) * | 2021-04-26 | 2022-11-03 | 上海申淇医疗科技有限公司 | Medical device |
CN116077808A (en) * | 2023-02-07 | 2023-05-09 | 康湃医疗科技(苏州)有限公司 | Medicine carrying towing device |
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