CN111870259B - Blood collection serum separation needle for animals - Google Patents

Blood collection serum separation needle for animals Download PDF

Info

Publication number
CN111870259B
CN111870259B CN202010764975.7A CN202010764975A CN111870259B CN 111870259 B CN111870259 B CN 111870259B CN 202010764975 A CN202010764975 A CN 202010764975A CN 111870259 B CN111870259 B CN 111870259B
Authority
CN
China
Prior art keywords
baffle
liquid
cavity
filtering membrane
piston
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202010764975.7A
Other languages
Chinese (zh)
Other versions
CN111870259A (en
Inventor
熊江林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Polytechnic University
Original Assignee
Wuhan Polytechnic University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Polytechnic University filed Critical Wuhan Polytechnic University
Priority to CN202010764975.7A priority Critical patent/CN111870259B/en
Publication of CN111870259A publication Critical patent/CN111870259A/en
Application granted granted Critical
Publication of CN111870259B publication Critical patent/CN111870259B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes

Abstract

The invention discloses an animal blood collection serum separation needle, which comprises a needle body, a filtering membrane and a collection container, wherein the needle body comprises a needle tube and a piston main body, and is provided with a liquid inlet arranged on the needle tube, a liquid outlet arranged on the piston main body and a liquid storage cavity communicated with the liquid inlet and the liquid outlet; the filtering membrane divides the liquid storage cavity into a first cavity and a second cavity, and is used for filtering out serum in blood in the first cavity into the second cavity; the collection container is connected with the second chamber in an on-off mode. In the invention, the liquid inlet is formed on the needle tube and the liquid outlet on the piston main body, thereby being convenient for direct circulation of blood or serum in the liquid storage cavity while enlarging the liquid storage space of the liquid storage cavity; the filtering membrane is arranged in the liquid storage cavity, and serum can be directly separated without transferring blood; the collection container can be communicated with the second chamber on-off, and after the serum is fully separated out, the serum can be directly collected through communicating with the second chamber. The invention has the advantages of convenient operation and effectively avoiding sample pollution.

Description

Blood collection serum separation needle for animals
Technical Field
The invention relates to the technical field of animal blood sampling, in particular to an animal blood collection and serum separation needle.
Background
At present, the method for obtaining animal serum generally comprises the steps of firstly, utilizing a syringe to draw an animal blood sample; transferring the extracted animal blood sample to a centrifuge tube, and placing the centrifuge tube in the centrifuge to separate serum or standing in a blood collection tube to wait for layering; finally, the separated serum is sucked out by a detector by using a pipette or a suction tube, and is transferred to a sample tube for preservation. The existing method for obtaining animal serum needs to transfer samples for many times, and is complex in process, so that the sample is easy to pollute and the detection result is influenced.
Disclosure of Invention
The invention mainly aims to provide an animal blood collection serum separation needle, and aims to solve the problem that the process is complicated in the traditional method for obtaining animal serum.
In order to achieve the above object, the present invention provides an animal blood collection serum separation needle, comprising:
the needle body comprises a needle tube and a piston main body movably arranged in the needle tube along the inner and outer directions, and the needle body is provided with a liquid inlet arranged in the needle tube, a liquid outlet arranged in the piston main body and a liquid storage cavity communicated with the liquid inlet and the liquid outlet;
the filtering membrane is arranged in the liquid storage cavity to divide the liquid storage cavity into a first cavity and a second cavity which are sequentially arranged along the liquid passing direction, and the filtering membrane is used for filtering out serum in blood in the first cavity into the second cavity; the method comprises the steps of,
and the collection container is connected with the second chamber in an on-off way.
Optionally, the needle tube is provided with a liquid inlet cavity;
the filtering membrane is arranged in the liquid inlet cavity and is arranged at intervals of the liquid inlet.
Optionally, the needle tube is provided with a liquid inlet cavity;
the piston main body is internally and externally penetrated with a liquid passing channel, an inlet of the liquid passing channel is communicated with the liquid inlet cavity, and an outlet of the liquid passing channel forms the liquid outlet;
the filtering membrane is arranged in the liquid passing channel.
Optionally, the filtering membrane is detachably installed at the inner end of the piston main body, and covers the inlet of the liquid passing channel.
Optionally, an annular groove is formed on the inner end surface of the piston main body around the outlet of the liquid passing channel;
the animal blood collection serum separation needle also comprises a mounting ring, wherein the mounting ring is clamped in the annular groove so as to limit the outer peripheral side part of the filtering membrane together with the annular groove.
Optionally, the piston main body is provided with a first baffle at the inlet of the liquid passing channel, and the first baffle is provided with a plurality of first through holes communicated with the liquid inlet cavity and the liquid passing channel;
the filtering membrane is arranged on the inner side surface of the first baffle.
Optionally, the piston main body comprises a piston head and a piston rod, the piston head is internally and externally provided with a threaded hole, the piston rod is internally and externally provided with the liquid passing channel, and the inlet end of the piston rod is provided with the first baffle;
the piston rod is in threaded fit with the threaded hole, so that the distance between the first baffle and the filtering membrane is adjusted by adjusting the threaded depth of the piston rod and the threaded hole.
Optionally, the piston main body comprises a piston head and a piston rod, a threaded hole is formed in the piston head along the inner and outer directions in a penetrating manner, the first baffle is arranged at the inner end of the threaded hole, the piston rod is provided with the liquid passing channel along the inner and outer directions in a penetrating manner, the inlet end of the piston rod is provided with a second baffle, and the second baffle is provided with a plurality of second through holes communicated with the liquid inlet cavity and the liquid passing channel;
the piston rod is in threaded fit with the threaded hole, so that the second baffle plate is in a conducting state of rotating to the second through hole to be communicated with the first through hole, and in a covering state of closing the second through hole and the first through hole.
Optionally, the piston hole is provided with a first limiting part, the piston rod is provided with a first matching part, and when the first matching part rotates to be abutted against the first limiting part, the second baffle is in the covering state; and/or the number of the groups of groups,
the piston hole is provided with a second limiting part, the piston rod is provided with a second matching part, and when the second matching part rotates to be abutted against the second limiting part, the second baffle is in the conducting state.
Optionally, the collection container is detachably connected to the outer end of the piston body.
According to the technical scheme provided by the invention, the liquid inlet is formed in the needle tube, the liquid outlet is formed in the piston main body, and the direct circulation of blood or serum in the liquid storage cavity is facilitated while the liquid storage space of the liquid storage cavity is enlarged; the filtering membrane is arranged in the liquid storage cavity, and can directly separate blood without transferring the blood; the collection container can be communicated with the second chamber on-off, and after the serum is fully separated out, the serum can be directly collected through communicating with the second chamber. The invention has the advantages of convenient operation and effectively avoiding sample pollution.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic cross-sectional view of an embodiment of an animal blood collection and serum separation needle according to the present invention, wherein the second baffle is in a closed state;
FIG. 2 is an enlarged schematic view of FIG. 1 at A;
FIG. 3 is a schematic cross-sectional view of the blood collection and serum separation needle of FIG. 1, wherein the second shield is in a conductive state;
FIG. 4 is an enlarged schematic view at B in FIG. 3;
fig. 5 is an enlarged schematic view at C in fig. 4.
Reference numerals illustrate:
reference numerals Name of the name Reference numerals Name of the name
100 Blood collection serum separation needle for animals 22 Piston rod
10 Needle tube 221 Liquid outlet
11 Liquid inlet 222 Liquid passage
12 Liquid inlet cavity 223 Second baffle plate
21 Piston head 224 Second via hole
211 Annular groove 30 Filtering membrane
212 First baffle plate 40 Collecting container
213 First via hole 50 Mounting ring
The achievement of the objects, functional features and advantages of the present invention will be further described with reference to the accompanying drawings, in conjunction with the embodiments.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be noted that, if directional indications (such as up, down, left, right, front, and rear … …) are included in the embodiments of the present invention, the directional indications are merely used to explain the relative positional relationship, movement conditions, etc. between the components in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are correspondingly changed.
In addition, if there is a description of "first", "second", etc. in the embodiments of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, the meaning of "and/or" as it appears throughout includes three parallel schemes, for example "A and/or B", including the A scheme, or the B scheme, or the scheme where A and B are satisfied simultaneously. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present invention.
At present, the method for obtaining animal serum generally comprises the steps of firstly, utilizing a syringe to draw an animal blood sample; transferring the extracted animal blood sample to a centrifuge tube, and placing the centrifuge tube in the centrifuge to separate serum or standing in a blood collection tube to wait for layering; finally, the separated serum is sucked out by a detector by using a pipette or a suction tube, and is transferred to a sample tube for preservation. The existing method for obtaining animal serum needs to transfer samples for many times, and is complex in process, so that the sample is easy to pollute and the detection result is influenced.
In view of the above, the present invention provides an animal blood collection serum separation needle, and fig. 1 to 5 are embodiments of the animal blood collection serum separation needle provided by the present invention.
The invention provides an animal blood collection serum separation needle 100 which is mainly applied to collection of animal blood and obtaining serum in the animal blood.
Referring to fig. 1 to 4, the animal blood collection serum separation needle 100 comprises a needle body, a filtering membrane 30 and a collection container 40, wherein the needle body comprises a needle tube 10 and a piston main body movably arranged in the needle tube 10 along the inner and outer directions, and the needle body is provided with a liquid inlet 11 arranged in the needle tube 10, a liquid outlet 221 arranged in the piston main body and a liquid storage cavity communicated with the liquid inlet 11 and the liquid outlet 221; the filtering membrane 30 is disposed in the liquid storage cavity to divide the liquid storage cavity into a first chamber and a second chamber which are sequentially disposed along the liquid passing direction, and the filtering membrane 30 is used for filtering out serum in blood in the first chamber into the second chamber; the collection container 40 is connected to the second chamber in an on-off manner.
In the technical scheme provided by the invention, the liquid inlet 11 is formed in the needle tube 10, the liquid outlet 221 is formed in the piston main body, and the direct circulation of blood or serum in the liquid storage cavity is facilitated while the liquid storage space of the liquid storage cavity is enlarged; the filtering membrane 30 is arranged in the liquid storage cavity, and can directly separate blood without transferring the blood; the collection container 40 may be connected to the second chamber, and after the serum is sufficiently separated out, the serum may be directly collected by being connected to the second chamber. The invention has the advantages of convenient operation and effectively avoiding sample pollution.
The specific structure of the needle body can refer to the existing injector, and generally comprises a needle tube 10 and a piston main body, wherein the needle tube 10 is provided with a liquid inlet 11 positioned at the top end, and the liquid inlet 11 is detachably connected with a needle head with a required specification; the needle tube 10 is generally cylindrical, and a liquid inlet cavity 12 is formed in the needle tube 10; the piston main body comprises a piston head 21 and a piston rod 22, and the piston head 21 is accommodated in the liquid inlet cavity 12 and is in piston fit with the liquid inlet cavity 12; the piston rod 22 is connected with the piston head 21, and at least part of the piston rod extends out of the liquid inlet cavity 12, so that the piston rod is convenient for an operator to hold.
The piston body is reciprocally movable along a predetermined path in the liquid inlet chamber 12, and for convenience of understanding, the piston body is reciprocally movably mounted in the liquid inlet chamber 12 along an inner-outer direction, and a direction from the piston head 21 to the piston rod 22 in the piston body is from the inner side to the outer side.
The design is different from a conventional injector, the piston body is provided with a liquid passing channel 222 communicated with the liquid inlet cavity 12, specifically, the liquid passing channel 222 is arranged along the inner and outer directions penetrating through the piston body, the liquid passing channel 222 is provided with an inlet, the inlet can be arranged at the inner end of the piston head 21, and the inlet of the liquid passing channel 222 is communicated with the liquid inlet cavity 12 of the needle tube 10; the liquid passage 222 is provided with an outlet, the outlet may be disposed at the outer end of the piston rod 22, and the outlet of the liquid passage 222 forms the liquid outlet 221. The liquid inlet cavity 12 and the liquid passing channel 222 together form the liquid storage cavity, which is helpful to enlarge the liquid storage space as much as possible in the limited needle body, thereby further enlarging the liquid storage space of the first cavity and the second cavity, and more blood can be filtered out more fully at a time.
The filtering membrane 30 separates the first chamber and the second chamber, so that after the needle is pricked into the animal blood vessel, animal blood enters the first chamber from the liquid inlet 11 under the action of the piston main body, and after the animal blood is kept stand for a preset time and a preset angle, only serum enters the second chamber through the filtering membrane 30 under the action of the filtering membrane 30, thereby realizing the filtering of the serum. The specific type of filter membrane 30 is referred to in the art and will not be described in detail herein.
The collection container 40 may be any size, any purpose container, such as a serum sample tube; the collecting container 40 is detachably connected with the piston rod 22 of the piston main body, so that the collecting container 40 can be conveniently detached and replaced; the collection container 40 is connected to the second chamber by changing the relative positional relationship with the piston rod 22 or by an additional arrangement such as a control valve, so that the collection container 40 is disconnected from the second chamber when the blood in the first chamber is not sufficiently available, i.e. the serum in the second chamber is not completely available; on the contrary, when the blood in the first chamber is fully used, that is, the serum in the second chamber is completely obtained, the collection container 40 is communicated with the second chamber, so that centralized collection and treatment of the serum are facilitated, and the possibility of contamination and deterioration of the serum can be reduced.
The filtering membrane 30 is disposed in the liquid storage cavity, and in one embodiment, the filtering membrane 30 is disposed in the liquid inlet cavity 12 and spaced from the liquid inlet 11. The filtering membrane 30 may be fixedly mounted to the inner wall of the needle tube 10, or may be adjustably mounted to the inner wall of the needle tube 10 in the up-down direction by, for example, a chute and slider structure. The filtering membrane 30 is disposed in the liquid inlet chamber 12, so that the space of the first chamber is fixed in size, and a set amount of animal blood can be drawn.
In another embodiment, the filtering membrane 30 is disposed in the liquid passing channel 222, and may be specifically disposed at an inlet of the liquid passing channel 222, a middle of the liquid passing channel 222, and the liquid outlet 221. The filtering membrane 30 is arranged at the piston main body, so that the pressure change in the liquid storage cavity caused by the piston movement of the piston main body does not substantially influence the filtering membrane 30, and the service life of the filtering membrane 30 is prolonged; in addition, the filtering membrane 30 is disposed at the plunger body, so that the filtering membrane 30 can be more conveniently assembled and disassembled when the plunger body is withdrawn from the needle tube 10.
For ease of understanding, the filtering membrane 30 is disposed in the liquid passing passage 222 as an example.
Specifically, in the present embodiment, the filtering membrane 30 is detachably mounted at the inner end of the piston body, and is disposed to cover the inlet of the liquid passing passage 222. Compared with the technical proposal that the filtering membrane 30 is arranged in the middle of the liquid passing channel 222, the filtering membrane 30 is arranged at the inlet of the liquid passing channel 222 and is easier to be disassembled and replaced; compared with the technical scheme that the filtering membrane 30 is arranged at the liquid outlet 221, the arrangement of the filtering membrane 30 at the inlet of the liquid passage 222 can effectively enlarge the liquid storage space of the second chamber, which is helpful for the sufficient filtering out of serum.
In order to avoid introducing other interference impurities into the blood or serum, referring to fig. 3 to 5, in this embodiment, an annular groove 211 is formed on an inner end surface of the piston body around an outlet of the liquid passing channel 222; the animal blood collection serum separation needle 100 further comprises a mounting ring 50, wherein the mounting ring 50 is clamped in the annular groove 211 so as to limit the outer peripheral side part of the filtering membrane 30 together with the annular groove 211. The material of the mounting ring 50 is optionally the same as that of the piston head 21, and when the mounting ring 50 and the annular groove 211 are provided to limit the outer peripheral side portion of the filtering membrane 30 together, the inner end surface of the mounting ring 50 is flush with or smoothly transited from the inner end surface of the piston head 21, so as to avoid interference to the piston movement of the piston head 21. Of course, the mounting ring 50 may be made of a different material than the piston head 21, and may be stronger than the piston head 21, thereby enhancing the strength of the piston head. The installation of the installation ring 50 and the annular groove 211 can realize the rapid disassembly and assembly of the filtering membrane 30.
Because the filtering membrane 30 has a soft texture, when the filtering membrane 30 covers the inlet of the liquid passage 222, the part of the filtering membrane 30 corresponding to the inlet of the liquid passage 222 is in a suspended state and is easily damaged due to the influence of the pressure change in the liquid storage cavity.
Based on the above, in an embodiment, the piston main body is provided with a first baffle 212 at the inlet of the liquid passing channel 222, and the first baffle 212 is provided with a plurality of first through holes 213 communicating with the liquid inlet chamber 12 and the liquid passing channel 222; the filtering membrane 30 is disposed on the inner side surface of the first baffle 212. The first through hole 213 may realize communication between the liquid passage 222 and the liquid inlet chamber 12, and the first baffle 212 may support the filtering membrane 30, so as to help reduce the influence of pressure variation in the liquid storage chamber on the filtering membrane 30.
The first baffle 212 may be disposed on the piston head 21, specifically, in an embodiment, the piston head 21 is provided with a threaded hole along the inner and outer directions, and the inlet end of the piston rod 22 is provided with the first baffle 212; the piston rod 22 is in threaded engagement with the threaded bore to adjust the distance between the first baffle 212 and the filter membrane 30 by adjusting the threaded depth of the two. By arranging the piston rod 22 to be in threaded engagement with the threaded hole, the piston rod 22 and the piston head 21 can be detachably connected, and the piston rod 22 simultaneously has a movable stroke rotating along the axis of the piston rod and a movable stroke moving inwards and outwards, so that before the animal blood is extracted by the animal blood collection serum separation needle 100, namely the piston main body forms negative pressure in the liquid storage cavity through moving inwards and outwards, the piston head 21 is regulated to be screwed in towards the piston head 21, namely the first baffle 212 is regulated to be close to the filtering membrane 30 until the piston head is abutted against the filtering membrane 30, and the filtering membrane 30 is supported and protected; on the contrary, when the blood collection and serum separation needle 100 has completed the blood collection operation and needs to be kept still for filtering out serum in blood, the piston head 21 may be adjusted to be rotated away from the piston head 21, that is, the first baffle 212 may be adjusted to be moved away from the filtering membrane 30, so as to increase the distance between the first baffle 212 and the filtering membrane 30, and avoid the part of the first baffle 212, which is not provided with the first through hole 213, from reducing the filtering effect of the filtering membrane 30.
Alternatively, the first baffle 212 may be disposed on the piston rod 22, referring to fig. 1 to 4, in this embodiment, the piston head 21 is provided with a threaded hole extending along an inner and outer direction, the first baffle 212 is disposed at an inner end of the threaded hole, the piston rod 22 is provided with the liquid passing channel 222 extending along an inner and outer direction, an inlet end of the piston rod 22 is provided with a second baffle 223, and the second baffle 223 is provided with a plurality of second through holes 224 communicating the liquid inlet chamber 12 and the liquid passing channel 222; the piston rod 22 is in threaded engagement with the threaded hole, so that the second baffle 223 has a conducting state in which the second through hole 224 communicates with the first through hole 213, and a covering state in which the second through hole 224 is closed with the first through hole 213. When the first baffle 212 is fixedly installed on the piston hole and the second baffle 223 is disposed on the piston rod 22, the second baffle 223 may rotate and move inward and outward under the driving of the piston rod 22, where the rotation of the second baffle 223 may realize the switching between the on state and the covered state, that is, indirectly realize the on-off connection between the collection container 40 and the second chamber; the second barrier 223 moves inward and outward to extend and expand the second chamber space.
Note that, the arrangement manner of the plurality of first vias 213 on the first barrier 212 and the arrangement manner of the plurality of second vias 224 on the second barrier 223 may be set identically, so that when the first barrier 212 and the second barrier 223 are overlapped, the plurality of first vias 213 are respectively communicated with the plurality of second vias 224, and the second barrier 223 is in a conducting state; conversely, when the first barrier 212 and the second barrier 223 are offset by a certain angle, the first plurality of vias 213 and the second plurality of vias 224 are respectively offset and blocked, and the second barrier 223 is in a closed state. Specifically, the circular end surface of the first baffle 212 may be divided into a plurality of sector areas, where a part of the sector areas is hollowed out to form the first via 213; the second barrier 223 and the second via 224 are adapted to the first barrier 212 and the first via 213.
Next, in the present embodiment, the piston hole is provided with a first limiting portion, the piston rod 22 has a first mating portion, so that the second baffle 223 is in the covering state when the first mating portion rotates to abut against the first limiting portion; and/or, the piston hole is provided with a second limiting part, the piston rod 22 is provided with a second matching part, and when the second matching part rotates to be abutted against the second limiting part, the second baffle 223 is in the conducting state. The limitation of the first limiting portion and the second limiting portion can limit the specific stroke of the rotation and the movement of the piston rod 22, and accurately define the position when the second baffle 223 reaches the closing state and the position when the second baffle 223 reaches the conducting state, so that the manual operation of an operator is facilitated. The first limiting portion and the second limiting portion are, for example, limiting protrusions protruding into the threaded hole, which will not be described in detail herein.
The foregoing description is only of the preferred embodiments of the present invention and is not intended to limit the scope of the invention, and all equivalent structural changes made by the description of the present invention and the accompanying drawings or direct/indirect application in other related technical fields are included in the scope of the invention.

Claims (1)

1. An animal blood collection serum separation needle, comprising:
the needle body comprises a needle tube and a piston main body movably arranged in the needle tube along the inner and outer directions, and the needle body is provided with a liquid inlet arranged in the needle tube, a liquid outlet arranged in the piston main body and a liquid storage cavity communicated with the liquid inlet and the liquid outlet;
the filtering membrane is arranged in the liquid storage cavity to divide the liquid storage cavity into a first cavity and a second cavity which are sequentially arranged along the liquid passing direction, and the filtering membrane is used for filtering out serum in blood in the first cavity into the second cavity; the method comprises the steps of,
the collection container is connected with the second chamber in an on-off mode;
the needle tube is provided with a liquid inlet cavity;
the filtering membrane is fixedly arranged on the inner cavity wall of the needle tube;
the piston main body is internally and externally penetrated with a liquid passing channel, an inlet of the liquid passing channel is communicated with the liquid inlet cavity, and an outlet of the liquid passing channel forms the liquid outlet; the liquid inlet cavity and the liquid passing channel jointly form the liquid storage cavity;
the piston main body comprises a piston head and a piston rod, a threaded hole is formed in the piston head along the inner side and the outer side in a penetrating mode, a first baffle is arranged at the inner end of the threaded hole, and a plurality of first through holes which are communicated with the liquid inlet cavity and the liquid passing channel are formed in the first baffle;
dividing the circular end face of the first baffle into a plurality of sector areas, wherein part of the sector areas are hollowed out to form the first via hole;
the first through hole can realize the communication between the liquid passing channel and the liquid inlet cavity; before negative pressure is formed in the liquid storage cavity by moving the piston main body from inside to outside, the first baffle is adjusted to approach the filtering membrane until the first baffle is abutted against the filtering membrane, so that the filtering membrane is supported and protected; when serum in blood is filtered out by standing, the first baffle is regulated to move away from the filtering membrane, so that the distance between the first baffle and the filtering membrane is increased;
the piston rod is internally and externally penetrated with the liquid passing channel, the inlet end of the piston rod is provided with a second baffle, and the second baffle is provided with a plurality of second through holes communicated with the liquid inlet cavity and the liquid passing channel; the second baffle and the second via are suitable for the arrangement of the first baffle and the first via; the second baffle can rotate and move inwards and outwards under the drive of the piston rod, and the rotation of the second baffle can realize the switching between a conducting state and a covering state; the second baffle moves inwards and outwards, so that the extension and expansion of the second chamber space can be realized;
the arrangement mode of the first through holes on the first baffle plate and the arrangement mode of the second through holes on the second baffle plate are the same, so that when the first baffle plate and the second baffle plate are overlapped, the first through holes are respectively communicated with the second through holes, and the second baffle plate is in a conducting state; when the first baffle plate and the second baffle plate are staggered by a certain angle, the first through holes and the second through holes are respectively staggered and are respectively shielded, and the second baffle plate is in a covering state;
the piston rod is in threaded fit with the threaded hole, so that the second baffle plate is in a conducting state of rotating to the second through hole to be communicated with the first through hole and a covering state of closing the second through hole and the first through hole;
the threaded hole is provided with a first limiting part, the piston rod is provided with a first matching part, and when the first matching part rotates to be abutted against the first limiting part, the second baffle is in the covering state; and/or the number of the groups of groups,
the threaded hole is provided with a second limiting part, the piston rod is provided with a second matching part, and when the second matching part rotates to be abutted against the second limiting part, the second baffle is in the conducting state; the first limiting part and the second limiting part are limiting protrusions protruding into the threaded holes;
the collection container is detachably connected with the outer end of the piston main body.
CN202010764975.7A 2020-07-31 2020-07-31 Blood collection serum separation needle for animals Active CN111870259B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010764975.7A CN111870259B (en) 2020-07-31 2020-07-31 Blood collection serum separation needle for animals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010764975.7A CN111870259B (en) 2020-07-31 2020-07-31 Blood collection serum separation needle for animals

Publications (2)

Publication Number Publication Date
CN111870259A CN111870259A (en) 2020-11-03
CN111870259B true CN111870259B (en) 2023-09-29

Family

ID=73205371

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010764975.7A Active CN111870259B (en) 2020-07-31 2020-07-31 Blood collection serum separation needle for animals

Country Status (1)

Country Link
CN (1) CN111870259B (en)

Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887466A (en) * 1974-02-27 1975-06-03 Becton Dickinson Co Serum/plasma separator cannula fluid by-pass type centrifugal valve cannula seal
US3945928A (en) * 1974-02-27 1976-03-23 Becton, Dickinson And Company Serum/plasma separators with centrifugal valves
US4459997A (en) * 1981-11-03 1984-07-17 Walter Sarstedt Kunststoff-Spritzgusswerk Blood extracting and centrifuging device
US5070884A (en) * 1989-03-14 1991-12-10 Eastman Kodak Company Needle device for safely collecting blood or injecting drugs
CN2287463Y (en) * 1997-01-03 1998-08-12 孙善初 Disposable blood sampling and serum separator
EP1084724A1 (en) * 1999-09-15 2001-03-21 Matthew Red Kay Syringe
JP2007003479A (en) * 2005-06-27 2007-01-11 Sekisui Chem Co Ltd Blood separation device
JP2007006973A (en) * 2005-06-28 2007-01-18 Sekisui Chem Co Ltd Blood sampling and separating apparatus
CN200973714Y (en) * 2006-11-17 2007-11-14 高凤玲 Blood collecting and separating integrated type blood collecting device
CN101663580A (en) * 2007-02-09 2010-03-03 米达威尼奇发展有限公司 Be used to separate apparatus and method with analyzing blood
CN201921703U (en) * 2011-02-17 2011-08-10 胡传水 Special test tube with filtering and disinfecting device
CN103260759A (en) * 2010-12-21 2013-08-21 通用电气医疗集团英国有限公司 Filtration device and method
CN205216586U (en) * 2015-12-15 2016-05-11 王文 Blood separating element and blood filtration ware
CN107669281A (en) * 2017-11-02 2018-02-09 犹银俊 Animal blood serum gathers test tube and serum separator
CN207423629U (en) * 2017-11-15 2018-05-29 济南金域医学检验中心有限公司 A kind of blood testing device for filtering impurities
CN208032060U (en) * 2018-05-16 2018-11-02 中国农业科学院北京畜牧兽医研究所 Novel pin hair style blood filter
CN108969844A (en) * 2018-06-29 2018-12-11 苏州市百世康医疗器械有限公司 A kind of infusion control valve
CN209221641U (en) * 2015-09-02 2019-08-09 雅致有限公司 Filter plant
CN209790967U (en) * 2019-03-20 2019-12-17 林侯汎 Device for extracting mononuclear cells in blood
CN209827712U (en) * 2019-04-09 2019-12-24 范桐坊 Bone marrow filter
CN110613505A (en) * 2018-06-18 2019-12-27 贺利氏医疗有限公司 Bone cement applicator with retractable mixing rod and method for producing bone cement
CN210037309U (en) * 2019-05-05 2020-02-07 郑州赛图康生物科技有限公司 Sample collection device and kit for detecting blood sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130074960A1 (en) * 2011-09-22 2013-03-28 Gregory S. Sundheim Portable, refrigerant recovery unit
US20150076069A1 (en) * 2013-09-13 2015-03-19 Scientific Plastic Products, Inc. Filter vial with limited piston stroke

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3945928A (en) * 1974-02-27 1976-03-23 Becton, Dickinson And Company Serum/plasma separators with centrifugal valves
US3887466A (en) * 1974-02-27 1975-06-03 Becton Dickinson Co Serum/plasma separator cannula fluid by-pass type centrifugal valve cannula seal
US4459997A (en) * 1981-11-03 1984-07-17 Walter Sarstedt Kunststoff-Spritzgusswerk Blood extracting and centrifuging device
US5070884A (en) * 1989-03-14 1991-12-10 Eastman Kodak Company Needle device for safely collecting blood or injecting drugs
CN2287463Y (en) * 1997-01-03 1998-08-12 孙善初 Disposable blood sampling and serum separator
EP1084724A1 (en) * 1999-09-15 2001-03-21 Matthew Red Kay Syringe
JP2007003479A (en) * 2005-06-27 2007-01-11 Sekisui Chem Co Ltd Blood separation device
JP2007006973A (en) * 2005-06-28 2007-01-18 Sekisui Chem Co Ltd Blood sampling and separating apparatus
CN200973714Y (en) * 2006-11-17 2007-11-14 高凤玲 Blood collecting and separating integrated type blood collecting device
CN101663580A (en) * 2007-02-09 2010-03-03 米达威尼奇发展有限公司 Be used to separate apparatus and method with analyzing blood
CN103260759A (en) * 2010-12-21 2013-08-21 通用电气医疗集团英国有限公司 Filtration device and method
CN201921703U (en) * 2011-02-17 2011-08-10 胡传水 Special test tube with filtering and disinfecting device
CN209221641U (en) * 2015-09-02 2019-08-09 雅致有限公司 Filter plant
CN205216586U (en) * 2015-12-15 2016-05-11 王文 Blood separating element and blood filtration ware
CN107669281A (en) * 2017-11-02 2018-02-09 犹银俊 Animal blood serum gathers test tube and serum separator
CN207423629U (en) * 2017-11-15 2018-05-29 济南金域医学检验中心有限公司 A kind of blood testing device for filtering impurities
CN208032060U (en) * 2018-05-16 2018-11-02 中国农业科学院北京畜牧兽医研究所 Novel pin hair style blood filter
CN110613505A (en) * 2018-06-18 2019-12-27 贺利氏医疗有限公司 Bone cement applicator with retractable mixing rod and method for producing bone cement
CN108969844A (en) * 2018-06-29 2018-12-11 苏州市百世康医疗器械有限公司 A kind of infusion control valve
CN209790967U (en) * 2019-03-20 2019-12-17 林侯汎 Device for extracting mononuclear cells in blood
CN209827712U (en) * 2019-04-09 2019-12-24 范桐坊 Bone marrow filter
CN210037309U (en) * 2019-05-05 2020-02-07 郑州赛图康生物科技有限公司 Sample collection device and kit for detecting blood sample

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
倪青,等.血清胰岛素.《糖尿病精准诊疗宝典》.中国科学技术出版社,2019,12. *

Also Published As

Publication number Publication date
CN111870259A (en) 2020-11-03

Similar Documents

Publication Publication Date Title
CN111870259B (en) Blood collection serum separation needle for animals
JP6319516B2 (en) Auto sampler
CN111870258B (en) Animal blood serum high-efficiency separating needle
CN219641332U (en) Underground water layered sampling device
CN211205139U (en) Detection device for detecting inner diameter of valve sleeve
CN202589701U (en) Electrically-controlled piston type medicament injector
CN114813302B (en) Multi-circulation tumor cell single sampling and automatic identifying machine
EP3837522A1 (en) Analysis system and methods of use thereof
CN214916218U (en) High accuracy liquid-transfering suction head
KR102252029B1 (en) Apparatus for micro particle treatment
CN208946055U (en) Infusion apparatus idler wheel feeds location structure
CN209138049U (en) A kind of organic automatic extraction apparatus
CN113621503A (en) Portable and rapid nucleic acid extraction device for nucleic acid detection
CN209791515U (en) Reaction kettle convenient for air discharge
CN208212691U (en) automatic filtration device controlled by P L C
CN106370483B (en) Seven-station turntable type heavy metal enrichment sampling device based on nano functional material
CN220729751U (en) Underground water stratified sampling device
CN220343298U (en) Invertebrate sampling separator
CN220304956U (en) Nuclear cell enrichment dyeing integrated equipment
CN112957790B (en) High-pressure filtering device
CN220304957U (en) Enrichment and dyeing integrated equipment for circulating tumor cells
CN116358980B (en) Tumor cell short-term test identification device
CN219369319U (en) Full-automatic tissue slice dyeing device
CN212818271U (en) Chemical extraction and separation device
CN213551989U (en) Novel fat biopsy needle

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant