CN111868220A

CN111868220A - Laundry detergent formulations

Info

Publication number: CN111868220A
Application number: CN201980015909.5A
Authority: CN
Inventors: 马修·A·布鲁姆; 布莱恩·星巴克
Original assignee: Dikang No7 System Co ltd
Current assignee: Dikang No7 System Co ltd; Decon7 Systems Inc
Priority date: 2018-01-17
Filing date: 2019-01-17
Publication date: 2020-10-30
Also published as: CA3089006A1; WO2019143825A1; KR20200133728A; CA3089023A1; EP3740547A1; JP7350341B2; JP2021511414A; JP7409667B2; JP2021511417A; WO2019143827A2; KR20200133726A; WO2019143821A1; CN111819271A; WO2019143827A3; AU2019209868A1; AU2019209860A1; EP3740548A4; CN112135896A; AU2019209866A1; MX2020007670A

Abstract

An improved surface decontamination process using a layered process based on a D7 formulation for pathogen/agent/toxin mobilization on a surface followed by pathogen/agent/toxin destruction, wherein the D7 formulation is supplemented with SSDX-12 to treat laundry, wherein the D7 formulation has a quaternary amine active as a disinfectant and a surfactant for soil and soil release and solubility on laundry.

Description

Laundry detergent formulations

CROSS-REFERENCE TO RELATED APPLICATIONS

This is PCT international patent application nos. 62/618,095, 62/618,096, 62/618,098, 62/618,100 and 62/618,104 of U.S. provisional patent application nos. 1, 17, 2018. The present application also claims priority from US non-provisional patent application No. 16/209,960, filed on day 4, 12/2018, which is a continuation of PCT international patent application No. PCT/US18/37817, filed on day 15, 6/2018, which claims priority from US provisional patent application No. 62/520,372, filed on day 15, 6/2017. The disclosure of the above application is incorporated herein by reference in its entirety.

Technical Field

Background

What is needed first in decontamination is to facilitate pathogen/agent/contaminant/toxin exposure to reactive mechanisms designed to combat it. On the surface, this requires:

inducing the ability to desorb species from the surface, or

Effecting hydraulic mobility (displacement) of the substance, or

Forcing the substance into a state susceptible to hydraulic pressure (dissolution)

The harmful substance may penetrate deeply into the network grain structure of the microscopic surface, making it difficult to displace. The use of water or other solvents alone may not create a suitable physiochemical environment sufficient to overcome the forces holding or shielding the substance in place.

Disclosure of Invention

Embodiments of the present invention describe the implementation of enhanced chemical formulations and the application of two patented products (DF-200 and SSDX-12) designed for decontamination, disinfection and renewal of surfaces exposed to chemical, biological, toxic industrial pollutants and residues. These two products are used for independent treatment of the decontamination strategy. The combination of two products in cooperation with each other presents a unique approach for decontamination and disinfection strategies.

SSDX-12 is a high-performance cleansing soap that is specifically used for the safe decontamination of aircraft. To implement the claims, it is desirable that the SSDX-12 exhibit corrosion resistance to aircraft metal alloys and sensitive equipment. It is also desirable that the product remove the residue of chemical weapons to acceptable standards. While the products are indeed effective in treating target surfaces, there remains a challenge to remediate currently dissolved and mobile chemical agents. In many cases, it is only unacceptable to flush the treatment agent into the environment.

The D7 formulation (hereinafter, "D7" or "D7 formulation") is a high-performance decontamination/disinfectant used to treat surfaces contaminated with bacteria, viruses, molds, mildew, toxic industrial chemicals, chemical weapons, and other pathogenic and harmful agents. D7 is able to facilitate rapid chemical repair of these problems by virtue of its unique ability to solubilize the normally water-insoluble target and expose it to chemical oxidation either directly or in the field of self-assembled minicell structures implemented in the formulation.

In one example, the D7 formulation extended the technology to include both oxidation and reduction reactions. Furthermore, D7 covers the handling of toxic industrial chemicals. It is also the first reference for bleach activators.

In another example, D7 extends to the fields of mold, disinfection and sterilization. The chemistry has not been changed or modified. In fact, D7 is closest to the utility that current products have.

Furthermore, D7 extends to the chemical area of DF-200. Furthermore, it encompasses data on the reaction rates for various toxic reagents. It is also an improvement of the original DF-100 in performance (with respect to reaction time and specificity) against mustard reagents. In one embodiment, D7 also incorporates different bleach activators.

The synergistic effect of the effectiveness of these two decontamination strategies is an advancement of the current advanced decontamination and surface remediation technologies, providing improvements urgently needed in these practices.

Drawings

Detailed Description

The SSDX-12 is designed to implement a safe, environmentally benign, low risk physiochemical tool that enables conditions favorable to the removal or unmasking of pathogens/agents/contaminants/toxins. By applying SSDX-12, the harmful substances can be hydraulically removed or made susceptible to hydraulic pressure.

In one example, the SSDX-12 can include a cleaning composition such as C8-22 alkyl dimethyl amine oxide surfactant, C6-12 alkyl dimethyl amine oxide surfactant, C8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant, and C12-14 secondary alcohol ethoxylate surfactant. The C8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant comprises from 0 to about 20 ethoxylated groups per molecule of C8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant. The C12-14 secondary alcohol ethoxylate surfactant includes from about 14 to about 16 ethoxylate groups per molecule of C12-14 secondary alcohol ethoxylate surfactant.

In another embodiment, a cleaning composition for cleaning exterior surfaces of a vehicle is provided. The cleaning composition includes from about 0.1% to about 5% by weight of a C8-16 alkyl dimethyl amine oxide surfactant, from about 0.1% to about 5% by weight of a C6-10 alkyl dimethyl amine oxide surfactant, from about 0.1% to about 5% by weight of a C10-14 alkyl polyethylene glycol sorbitan fatty ester surfactant, and from about 0.1% to about 5% by weight of a C12-14 secondary alcohol ethoxylate surfactant, the secondary alcohol ethoxylate surfactant including from about 14 to about 16 ethoxylate groups per C12-14 secondary alcohol ethoxylate surfactant molecule. The C10-14 alkyl polyethylene glycol sorbitan fatty ester surfactant comprises from 0 to about 6 ethoxylated groups per molecule of C8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant. The C12-14 secondary alcohol ethoxylate surfactant includes from about 14 to about 16 ethoxylate groups per molecule of C12-14 secondary alcohol ethoxylate surfactant. C8-16 alkyl dimethyl amine oxide surfactant, C6-10 alkyl dimethyl amine oxide surfactant, C10-14 alkyl polyethylene glycol sorbitan fatty ester surfactant, and C12-14 secondary alcohol ethoxylate surfactant are provided in a 1:1:1:1 ratio in a cleaning composition. The cleaning composition is effective to remove chemical warfare agents from the exterior surfaces of the vehicle when applied to the vehicle.

In one application, a method of cleaning exterior surfaces of a vehicle using the above cleaning composition may be applied. The method includes providing a cleaning composition, applying the cleaning composition to an exterior surface of the vehicle, and rinsing the exterior surface of the vehicle with water.

However, once displaced from its microscopic position, the substance may be exposed to a spectrum of reactivity (photoelectric radiation, oxidation, chemical modification by external substances) that contributes to its chemical transformation. In other words, the fact that the SSDX-12 can be applied to a vehicle surface as a cleaning composition, for example, does not mean that the dissolved solution is non-toxic or environmentally friendly. That is, in this state, the toxin becomes extremely susceptible to natural forces, which promotes its inevitable conversion to its lowest energy state.

Concrete surfaces may appear solid from our perspective, but when viewed microscopically, may consist of a complex network of paths. This is the same as any porous surface. In many cases, the proximity check reveals a maze. Delivering chemicals into such a micro environment requires overcoming significant surface tension. Surface tension is a property of a liquid that defines how the liquid spreads out on a surface and the degree to which the liquid penetrates into the surface. The proprietary formulation ingredients of D7 enabled extremely low surface tension values to be obtained at the surface. These values are not equilibrium values, but dynamic values. Upon penetration into the surface, the turbulent solution produced by the effervescence of decomposing hydrogen peroxide will continually renew itself at its leading edge. These brief ultra-low surface tension values enable deeper penetration of the active chemical applied in D7. The cationic quaternary amine surfactant coupled with the alkaline pH carbonated buffer system enables a more efficient osmotic delivery pathway for the complex cleaning chemistry applied in D7. The product behaves in a similar manner to the mechanism after hydraulic fracture without a high pressure pump.

Alkaline carbonates (based on potassium) interact with the primary negatively biased surface.

The quaternary amine strongly adsorbs on the negatively biased surface.

The hydraulic channel is open, allowing the delivery of cleaning forces in the form of water, peroxide and other formulation non-ionic substances.

D7 also provides advantages over the prior art in terms of the ability to permeate/eradicate biofilms compared to conventional forms. In one example, the biofilm comprises a secreted chemical matrix that protects pathogen colonies from invasive threats. These membranes have a nutrient embankment, a respiratory embankment and a transpiration embankment, and their exact nature is the subject of intense research. The physiochemical solution properties of D7 interact in a manner that effectively and sufficiently disrupts these surfaces. The dissolution characteristics and oxidation from peroxide and peracetic acid species effectively "pry" the surface of the membrane and in some cases help to defeat the functional dykes, causing eventual failure. Biofilms effectively organize water in secreted extracellular matrices, which in many cases are destroyed by D7 detergent mechanisms.

The example of D7 describes an enhanced chemical formulation designed for decontamination, disinfection, and renewal of surfaces exposed to chemical, biological, and toxic industrial contaminants and residues. This formulation improves the prior art by: expanding the range of efficacy, shortening treatment times, modifying chemical properties, achieving lower effective doses and expanding the list of chemical agents repaired by them. The formulations described herein may also be applied at different concentrations to achieve decontamination goals (cleaning, sterilization, disinfection, high level disinfection, mold repair, biofilm repair, target decontamination).

The intent of this effort is to make embodiments of D7 more and more designed to perform specific tasks in varying forms. In one embodiment, aspects of the invention may be formulated with generation 1 versions of quaternary amines (ADBACs). It is believed that the type of extended quaternary amine may contribute to efficacy against a wider range of pathogens or greater effectiveness against biofilms. Of these two properties, biofilm effectiveness may be a major value proposition.

In addition, D7 provides a simple list of components. D7 was not made of the singular component. It is made from commonly used, mild, readily available materials. The combination of which produces a net effect greater than the simple sum of each.

The physical properties embodied in D7 partially explain its success. Factors such as dynamic surface tension, critical micelle concentration, micelle aggregation number, solvent dissociation potential and solution polarity all contribute to the mysterious nature of D7.

A more dramatic effect of D7 was produced by micelle formation. These micelles act as a micro-reaction plant in which toxic substances react with activated oxygen species, rendering them neutralized or harmless.

As a starting point, the application of D7 in response to biofilm problems appears to be a valuable efficacy for consumers. Protection against biofilms that protect bacterial communities is actually warranted against the prokaryotic bacteria themselves. The efficacy of D7 against various organisms is listed below:

Considering the algebraic relationship of the quadrivalence, the following comparisons are relevant.

Generation 5 quaternary amines. This category is a mixture of generations 1 and 4. The innovative approach can be rapidly multiplied when considering the arrangement of different generation 1 chemicals with generation 4 variants. In one embodiment, the D7 formulation includes:

in one embodiment, the surfactant represented by item 5 and the dimethyl dialkyl quaternary amine provide the micelle produced in the D7 formulation with enhanced structure.

These surfactants can modify the goiy-Chapman-schtenn layer (Gouy-Chapman-Stern layer) to the point of enhanced and improved ability to allow the agent to dissolve into the micelles more rapidly.

In one example, the surfactant can modify the goi-chappmann-schltren layer, which can be related to the rate of agent decontamination, or it can be the degree of agent decontamination.

This embodiment of the invention may have different physical properties. The efficacy characteristics of this version will also differ. The study of the efficacy profile should be from a diluted version (probably a 1:100 dilution of the final product) to a full version. The diluted version may be considered to be a surface that has been cleaned and free of biofilm. In one embodiment, the condensed version will be considered a situation where there are more fouls (live animal equipment, process plant, high biofilm potential location). The various embodiments of the invention with respect to different dilutions (bacteria, biofilm, efficacy of nebulization) can achieve various degrees of application in addition to that disclosed in fig. 1.

This improvement over the prior art enables the expectation of a full spectrum of products that can handle sensitive cleaning and sterilization situations, such as those encountered in food contact environments. In these environments, the product is typically capable of being applied to a target surface in the form of a spray and wiped so that the cleaning/disinfecting formulation is distributed over the entire surface. In one embodiment, aspects of the present invention may require approval by an administrative supervisory authority prior to use. In this case, this is commonly referred to as a "leave-on" product. There are legal limitations that permit tag components for this type of use. The object of this improved implementation is to achieve this type of use. Full strength versions of the product are intended for use in highly hazardous environments where large numbers of fouls are expected, such as moving animal barns. This represents the other end of the product spectrum. For pesticidal embodiments, regulatory supervision is also necessary. It is expected that there will be many situations between these two ends where a product whose strength is adjusted will meet the needs. Examples of such situations are provided in the ranges above.

It is generally desirable to facilitate a more rapid transition to a less harmful state. Pathogens, toxic industrial chemicals or other undesirable substances are not attacked in the surrounding environment, except for reactive agents that are common in the surroundings. Natural remedies for treating infections include, for example, organism predation, hydrolysis by water, photolysis by electromagnetic radiation, absorption by substrates, and pathogen shielding by the environment. If the pathogen is soluble in water, then a simple rinse is sufficient. The dynamic timeframe for these operations may be in the immediate to very long slow transition period range. Delivery of reactive chemical actives in oxidized or nucleophilic substitution forms is a well known effective treatment strategy in common practice. It is the route by which a large number of agents deliver their effective dose. After oxidation of a substance, it is generally more susceptible to environmental degradation by one or more of the aforementioned mechanisms. Delivery of oxidative activity to a target is not always straightforward. For example, in many disinfection and purification applications, the use of bleaching agents is common practice. Bleaching agents are aqueous based solutions whose ability to penetrate and engage pathogens is limited by the physiochemical barrier embodied on the treated substrate. Nothing happens if the biocide is not accessible to the target pathogen to react. Therefore, the disinfecting and purifying agent is formulated with substances satisfying the following conditions: a physiochemical barrier that can overcome interfacial tension and surface energy to deliver substances in close proximity for reaction. Furthermore, materials that are not soluble in water may not be susceptible to reactions based on limited exposure to reactive conditions.

As explained above, D7 is a formulation that overcomes the physiochemical barrier to deliver reactive oxide species to pathogenic targets and, by virtue of its design, aids in the ability to make resistant species solutions in which they are subsequently susceptible to oxidation by the mechanisms embodied by D7. This new version of the formulation is an enhancement of the previous version and shows a more stable and efficient ability to perform decontamination/disinfection tasks. By changing the surfactant characteristics of the formulation, we were able to demonstrate faster decontamination times and more comprehensive protection against protective pathogen layers, leading to better repair results.

Since D7 is a scavenger that transfers chemical oxidation energy in a safe, dilute form for the purpose of promoting oxidation of toxins to less harmful or completely benign decomposition products, D7 chemically treats toxins by promoting oxidation and thus accelerating the decontamination process. D7 will itself act to promote decontamination. Administration of SSDX-12 prior to D7 can enhance the net effect by achieving displacement of the adsorbed species.

D7 has been applied to select laundry problems and successfully decontaminate and sterilize important garments. The ability of D7 to perform these tasks has been demonstrated in a number of independent laboratory tests. D7 has as one of its major active ingredients a quaternary amine that acts as a powerful disinfectant and surfactant for loosening and dissolving soils and soils commonly found on garments. It is well known that cationic surfactant based cleaners do not behave as anionic or neutral surfactants in the context of laundry.

SSDX-12 has been applied to high-level decontamination missions associated with aircraft and has been certified by a number of tests and military agencies. It has shown a highly efficient ability to remove refractory materials deep inside the micro-grain structure of aircraft aluminum. As a cleaning agent for critical use on critical surfaces, it may be an option.

It is proposed to use the modified SSDX-12 as the primary detergent for washing purposes, followed by treatment with D7 for final purification as a combination that can be patented.

The foregoing description and drawings merely explain and illustrate the invention and the invention is not limited thereto. While the specification has been described with respect to certain embodiments or examples, numerous details are set forth for the purpose of illustration. Accordingly, the foregoing merely illustrates the principles of the invention. For example, the present invention may be embodied in other specific forms without departing from its spirit or essential characteristics. The described arrangements are illustrative and not restrictive. It will be apparent to those skilled in the art that the present invention is susceptible to additional embodiments or examples and that certain of these details described in the present application can be varied considerably without departing from the basic principles of the invention. It will thus be appreciated that those skilled in the art will be able to devise various arrangements which, although not explicitly described or shown herein, embody the principles of the invention and are thus within its spirit and scope.

While various embodiments have been described above, it should be understood that such disclosure is presented by way of example only, and not limitation. Thus, the breadth and scope of the subject compositions and methods should not be limited by any of the above-described exemplary embodiments, but should be defined only in accordance with the following claims and their equivalents.

Having now fully described the subject compositions and methods, it will be appreciated by those of ordinary skill in the art that this can be done within a wide and equivalent range of conditions, formulations, and other parameters without affecting the scope thereof or any embodiment thereof. All cited patents, patent applications, and publications are incorporated herein by reference in their entirety.

Surface cleaning formulation

Background

inducing the ability to desorb species from the surface, or

Effecting hydraulic mobility (displacement) of the substance, or

SUMMARY

Detailed Description

Concrete surfaces may appear solid from our perspective, but when viewed microscopically, may consist of a complex network of paths. This is the same as any porous surface. In many cases, the proximity check reveals a maze. Delivering chemicals into such a micro environment requires overcoming significant surface tension. Surface tension is a property of a liquid that defines how the liquid spreads out on a surface and the degree to which the liquid penetrates into the surface. The proprietary formulation ingredients of D7 enabled extremely low surface tension values to be obtained at the surface. These values are not equilibrium values, but dynamic values. Upon penetration into the surface, the turbulent solution produced by the effervescence of decomposing hydrogen peroxide will continually renew itself at its leading edge. These brief ultra-low surface tension values enable deeper penetration of the active chemical applied in D7. The cationic quaternary amine surfactant coupled with the alkaline pH carbonated buffer system achieves more effective osmotic delivery of the complex cleaning chemistry applied in D7. The product behaves in a similar manner to the mechanism after hydraulic fracture without a high pressure pump.

The quaternary amine strongly adsorbs on the negatively biased surface.

D7 is a scavenger that delivers chemical oxidation energy in a safe, dilute form for the purpose of promoting oxidation of toxins to less harmful or completely benign decomposition products. D7 chemically treats the toxins by promoting oxidation and thus speeding the decontamination process. D7 will itself act to promote decontamination. Administration of SSDX-12 prior to D7 can enhance the net effect by achieving displacement of the adsorbed species.

In one embodiment, an equivalent dose of D7 and SSDX-12 at a ratio of 15:1 is required to achieve the target results with the correct properties and surface cleansing action.

In another embodiment, BTC 8358 may be used in place of BTC 888 for the generation 5 tetravalent species in improving the foaming characteristics of the combination of D7 and SSDX-12. In one example, about 4.0% of such modified generation 5 tetravalent species may have desirable results of reducing foaming when a combination of D7 (with the addition of 15:1 or 30:1 equivalent doses of SSDX-12) is applied to a given surface to treat contaminants.

Claims

1. An improved surface decontamination method using a layered approach based on a D7 formulation that performs pathogen/agent/toxin mobilization on the surface followed by pathogen/agent/toxin destruction, wherein the D7 formulation is supplemented with SSDX-12 to treat laundry, wherein the D7 formulation has a quaternary amine active as a disinfectant and a surfactant for soil and stain release and solubility on the laundry.

2. An improved surface decontamination method using a layered approach based on a D7 formulation that performs pathogen/agent/toxin mobilization on the surface followed by pathogen/agent/toxin destruction, wherein the D7 formulation has SSDX-12 added at an equivalent dose of a ratio of 15:1 or 30:1, wherein BTC8358 replaces about 4.0% BTC 888 for the 5 th generation tetravalent species of D7.