CN111868074A - Hpv免疫疗法 - Google Patents

Hpv免疫疗法 Download PDF

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Publication number
CN111868074A
CN111868074A CN201980019740.0A CN201980019740A CN111868074A CN 111868074 A CN111868074 A CN 111868074A CN 201980019740 A CN201980019740 A CN 201980019740A CN 111868074 A CN111868074 A CN 111868074A
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hpv
subject
cell
peptide
antigen
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CN201980019740.0A
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Chinese (zh)
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R·肯纳
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QIMR Berghofer Medical Research Institute
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Queensland Institute of Medical Research QIMR
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/10—Peptides having 12 to 20 amino acids
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
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    • C07K16/084—Papillomaviridae (F); Polyomaviridae (F), e.g. SV40, BK virus or JC virus
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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CN201980019740.0A 2018-01-24 2019-01-23 Hpv免疫疗法 Pending CN111868074A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862621279P 2018-01-24 2018-01-24
US62/621,279 2018-01-24
PCT/IB2019/000131 WO2019145792A1 (en) 2018-01-24 2019-01-23 Hpv immunotherapy

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CN111868074A true CN111868074A (zh) 2020-10-30

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CN201980019740.0A Pending CN111868074A (zh) 2018-01-24 2019-01-23 Hpv免疫疗法

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Country Link
US (1) US20210046114A1 (https=)
EP (1) EP3743436A4 (https=)
JP (2) JP2021511054A (https=)
CN (1) CN111868074A (https=)
AU (2) AU2019213286A1 (https=)
CA (1) CA3088837A1 (https=)
WO (1) WO2019145792A1 (https=)

Cited By (1)

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CN115867295A (zh) * 2020-03-23 2023-03-28 昆士兰医学研究所理事会 用于靶向hpv感染细胞的组合物和方法

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Publication number Priority date Publication date Assignee Title
WO2025088530A1 (en) * 2023-10-24 2025-05-01 Treadwell Therapeutics T cell receptors and methods of use thereof

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