CN111861367A - Management method and system for sample sequencing in laboratory - Google Patents
Management method and system for sample sequencing in laboratory Download PDFInfo
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- CN111861367A CN111861367A CN202010517769.6A CN202010517769A CN111861367A CN 111861367 A CN111861367 A CN 111861367A CN 202010517769 A CN202010517769 A CN 202010517769A CN 111861367 A CN111861367 A CN 111861367A
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- G06—COMPUTING; CALCULATING OR COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q10/00—Administration; Management
- G06Q10/10—Office automation; Time management
- G06Q10/103—Workflow collaboration or project management
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
- G06K7/10—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation
- G06K7/10009—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves
- G06K7/10019—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves resolving collision on the communication channels between simultaneously or concurrently interrogated record carriers.
- G06K7/10079—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves resolving collision on the communication channels between simultaneously or concurrently interrogated record carriers. the collision being resolved in the spatial domain, e.g. temporary shields for blindfolding the interrogator in specific directions
- G06K7/10089—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves resolving collision on the communication channels between simultaneously or concurrently interrogated record carriers. the collision being resolved in the spatial domain, e.g. temporary shields for blindfolding the interrogator in specific directions the interrogation device using at least one directional antenna or directional interrogation field to resolve the collision
- G06K7/10099—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation sensing by radiation using wavelengths larger than 0.1 mm, e.g. radio-waves or microwaves resolving collision on the communication channels between simultaneously or concurrently interrogated record carriers. the collision being resolved in the spatial domain, e.g. temporary shields for blindfolding the interrogator in specific directions the interrogation device using at least one directional antenna or directional interrogation field to resolve the collision the directional field being used for pinpointing the location of the record carrier, e.g. for finding or locating an RFID tag amongst a plurality of RFID tags, each RFID tag being associated with an object, e.g. for physically locating the RFID tagged object in a warehouse
Abstract
The invention provides a management method for sample sequencing in a laboratory, which comprises the following steps: reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and obtaining a first sequencing result of the target sample; monitoring transfer information of a target sample in a target area, and adjusting a first sequencing result based on the transfer information to obtain a second sequencing result; and saving and displaying the second sequencing result. Through the accurate positioning of electron memo, obtain the position condition of sample, fine solution present loaded down with trivial details operation, increased the accuracy of sample management, overcome the drawback that exists at present, make laboratory sample management efficiency higher.
Description
Technical Field
The invention relates to the technical field of laboratory management, in particular to a management method and a management system for laboratory sample sequencing.
Background
Sample management in a laboratory is the first key process to enter a laboratory management system. The source input is effectively managed, so that the rigor of each preparation work before inspection can be ensured, errors can be effectively avoided, the normal development of subsequent experiments can be ensured, and the traceable and traceable sample information can be realized.
At present, most of laboratory samples mainly adopt traditional detection information, and need to be recorded, stored and backed up on the basis of initial records of a laboratory. Therefore, the operation steps are complex, the error rate is high, the data loss condition is serious, errors are difficult to make up, and great difficulty is caused to sample management in a laboratory.
The invention provides a management method and a system for laboratory sample sequencing, which are used for acquiring the position condition of a sample through the accurate positioning of an electronic note, well solving the current complicated operation, increasing the accuracy of sample management, overcoming the current defects and ensuring that the laboratory sample management efficiency is higher.
Disclosure of Invention
The invention provides a management method and a management system for laboratory sample sequencing, which are used for solving the technical problems.
The invention provides a management method for sample sequencing in a laboratory, which comprises the following steps:
reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and obtaining a first sequencing result of the target sample;
monitoring transfer information of the target sample in a target area, and adjusting the first sequencing result based on the transfer information to obtain a second sequencing result;
And saving and displaying the second sequencing result.
In one possible way of realisation,
the step of obtaining a first sequencing result for the target sample comprises:
the method comprises the steps of inductively reading a first electronic tag arranged on a sample body of a target sample;
sensing and reading a second electronic tag of the sample body, which is placed at a corresponding target position;
establishing a one-to-one corresponding relation between the first electronic tag and the second electronic tag;
and acquiring a first sequencing result of the target sample according to the one-to-one correspondence.
In one possible way of realisation,
based on the transfer information, adjusting the first sorting result, and obtaining a second sorting result includes:
adjusting the electronic information in the second electronic tag of the transfer placement position based on the transfer information;
the original corresponding relation between a first electronic tag corresponding to a target sample to be transferred and a second electronic tag corresponding to an original target position is released, and a new corresponding relation between the second electronic tag corresponding to the transfer placement position and the first electronic tag corresponding to the target sample to be transferred is reestablished;
and adjusting the first sequencing result according to the new corresponding relation to obtain a second sequencing result.
In one possible way of realisation,
after the second sorting result is saved and displayed, the method further comprises the following steps:
acquiring a transfer placement position of the target sample based on the transfer information;
determining the position attribute and the position environment of the transfer placement position based on a laboratory sample storage database, and simultaneously determining the sample attribute of the target sample;
judging whether the target sample placed in the transfer placing position is qualified or not according to the position attribute, the position environment and the sample attribute;
if the second sorting result is qualified, keeping the second sorting result unchanged;
and if not, pushing new information to be placed related to the target sample, adjusting the second sorting result to obtain a third sorting result, and displaying and storing the third sorting result.
In one possible way of realisation,
in the process of monitoring the transfer information of the target sample in the target area, the method further comprises the following steps:
determining a target sample to be transferred according to a transfer instruction input by a laboratory worker;
detecting whether the target sample to be transferred is qualified or not, and monitoring and acquiring transfer information of the target sample to be transferred in a target area if the target sample to be transferred is qualified;
Otherwise, storing the target sample to be transferred to an idle area, and performing first alarm reminding;
wherein, the step of detecting whether the target sample to be transferred is qualified comprises the following steps:
collecting a sample of the target sample to be transferred;
based on n preset measurement indexes, the sample samples are measured one by one, and a first measurement result w1 ═ { w1,w2,...,wnIn which wnThe first measurement result corresponding to the nth measurement index is represented;
determining a first integrated weight value S1 for the sample thumbnail based on the first measurement;
S1＝w1β1+w2β2+...+wnβn；
wherein, betanRepresents an index weight factor corresponding to the nth measurement index, and beta1+β2+...+βn＝1；
Sorting the N measurement indexes from large to small based on the index occupation ratio to obtain second measurement results w2 ═ w { corresponding to the first N measurement indexes21,w22,...,w2NIn which w2NThe second measurement result corresponding to the Nth measurement index is represented;
determining a second integrated weight value S2 for the sample thumbnail based on the second measurement;
S2＝w21β21+w22β22+...+w2Nβ2N；
wherein, beta2NRepresents an index weight factor corresponding to the Nth measurement index, and beta21+β22+...+β2N＜1；
Determining a difference between the first and second integrated weight values S1 and S2;
when the difference value is smaller than a preset value, judging that the sample hand sample is qualified, and executing a second alarm prompt;
And when the difference is not less than the preset value, judging that the sample small sample is unqualified, and executing third alarm reminding.
In one possible way of realisation,
in the process of reading the sample body of the target sample and the electronic tags on the target positions in one-to-one correspondence, the method further comprises the following steps:
sending a first connection protocol to a first electronic tag on a sample body of the target sample, and reading first electronic information of the first electronic tag;
meanwhile, a second connection protocol is sent to a second electronic tag on a target position corresponding to the target sample one by one, and second electronic information of the second electronic tag is read;
when the first electronic information and/or the second electronic information are not read, monitoring the body information of the sample body of the target sample, and simultaneously monitoring the bit information of the corresponding target bit;
optimizing the first sorting result according to the body information and the bit information;
wherein the body information includes: the shape information of the sample body, the color information of the sample body and the unique identification information of the sample body;
the bit information includes: the size of the slot position for placing the target position, the shape of the slot position for placing the target position and the unique identification information of the target position.
In one possible way of realisation,
acquiring the initial sample mass M of the target sample, and measuring the mass change information of the target sample in a preset time period through D pressure sensors of target positions corresponding to the target sample one by one;
calculating the average consumption efficiency mu of the target sample in a preset time period according to the quality change information;
wherein m represents the sampling times of the target sample in a preset time period; mjiThe pressure value measured by the jth pressure sensor after the ith target sample is sampled is represented; mji+1The pressure value measured by the jth pressure sensor after the ith +1 time of sampling the target sample is represented; t isi+1The sampling time interval between the ith and the (i + 1) th sampling of the target sample is represented; mj1Represents the pressure value measured by the jth pressure sensor after the 1 st sampling of the target sample; t is1Representing the sampling time interval between no sampling and the sampling of the target sample at the 1 st time;
acquiring a historical use time set of the target sample, and determining a frequent use stage of the target sample according to the historical use time set;
and adjusting and reminding the current position of the target sample according to the frequent use stage and the average consumed power.
In one possible way of realisation, the device,
according to the position attribute, the position environment and the sample attribute, the process of judging whether the target sample placed on the transfer placing position is qualified comprises the following steps:
calibrating a current transfer placement position;
based on a placing position space table, carrying out sample area division on a laboratory to obtain p sample areas, and calibrating the current transfer placing position in a corresponding first sample area;
determining an environmental attribute X of the first sample region;
determining a first relationship y1 of the current transfer placement bit and the first sample region;
determining a second association of the current transfer placement bit with an adjacent placement bit in the first sample regionSystem y2 ═ y21,y22,y23,y24}；
Wherein, y21Forward placement bit information indicating the current transfer placement bit; y is22Rear placement bit information representing the current transfer placement bit; y is23Left placement bit information representing the current transfer placement bit; y is24Right placement bit information representing the current transfer placement bit;
according to the first relation and the second relation, calculating the association degree Y of the current transfer placement position based on the first sample area;
wherein H (y1) represents a position attribute correlation function based on the first relationship y 1; h (y2) represents a position attribute association function based on a second relationship y 2; y represents current transfer placement bit information; e represents a natural constant;
Calculating the matching degree Z of the target sample corresponding to the transfer placement and the current placement position;
wherein H' (z0, z1, z2, z3, z4) represents a sample property association function based on the target sample z0 at the current placement position and the target sample z1 at the front placement position, the target sample z2 at the rear placement position, the target sample z3 at the left placement position, and the target sample z4 at the right placement position;
calculating a comprehensive placement value R of the target sample placed on the current transfer placement position according to the environment attribute X, the association degree Y and the matching degree Z;
R＝a1X+a2Y+a3Z；
wherein a1 represents the environmental factor of the first sample area; a2 denotes a position association factor based on the current placement bit; a3 denotes a sample correlation factor based on the current placement position; and a1+ a2+ a3 is 1;
when the R is larger than a standard placing value, judging that the target sample placed on the transfer placing position is qualified;
otherwise, judging that the target sample placed on the transfer placing position is unqualified, and executing fourth alarm reminding.
The invention provides a management system for sample sequencing in a laboratory, which comprises:
the reading module is used for reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and acquiring a first sequencing result of the target sample;
The monitoring module is used for monitoring the transfer information of the target sample in the target area, and adjusting the first sequencing result based on the transfer information to obtain a second sequencing result;
and the display module is used for storing and displaying the second sequencing result.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.
The technical solution of the present invention is further described in detail by the accompanying drawings and embodiments.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a flow chart of a method for managing sample ordering in a laboratory in accordance with an embodiment of the present invention;
FIG. 2 is a block diagram of a system for managing sample ordering in a laboratory in accordance with an embodiment of the present invention.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
The invention provides a management method for sample sequencing in a laboratory, which comprises the following steps as shown in figure 1:
step 1: reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and obtaining a first sequencing result of the target sample;
step 2: monitoring transfer information of the target sample in a target area, and adjusting the first sequencing result based on the transfer information to obtain a second sequencing result;
and step 3: and saving and displaying the second sequencing result.
In this embodiment, the electronic tag may be an active electronic tag having high corrosion resistance;
in this embodiment, the monitoring target area is a laboratory, and the range of movement of the target sample may be the entire laboratory.
In this embodiment, for example: the electronic information of the electronic tag of the sample body is 01, the electronic information of the electronic tag on the corresponding target position is 001, and at the moment, 01 corresponds to 001, namely the first sequencing result.
In this embodiment, for example: the information is transferred to 002 corresponding to the target position, and at this time, 01 corresponds to 002, which is the second sorting result.
The beneficial effects of the above technical scheme are: through electronic tags's accurate positioning, obtain the position condition of sample, fine solution present loaded down with trivial details operation, increased the accuracy of sample management, overcome the drawback that exists at present, make laboratory sample management efficiency higher.
The invention provides a management method for sample sequencing in a laboratory, which comprises the following steps of:
the method comprises the steps of inductively reading a first electronic tag arranged on a sample body of a target sample;
sensing and reading a second electronic tag of the sample body, which is placed at a corresponding target position;
establishing a one-to-one corresponding relation between the first electronic tag and the second electronic tag;
and acquiring a first sequencing result of the target sample according to the one-to-one correspondence.
Preferably, the first sequencing result is based on raw data of the electronic tag corresponding to the sample.
The beneficial effects of the above technical scheme are: the obtained first sequencing result is convenient for comparing the sequencing results of the moved samples in the rear.
The invention provides a management method for sample sorting in a laboratory, which adjusts a first sorting result based on transfer information, and a process of obtaining a second sorting result comprises the following steps:
Adjusting the electronic information in the second electronic tag of the transfer placement position based on the transfer information;
the original corresponding relation between a first electronic tag corresponding to a target sample to be transferred and a second electronic tag corresponding to an original target position is released, and a new corresponding relation between the second electronic tag corresponding to the transfer placement position and the first electronic tag corresponding to the target sample to be transferred is reestablished;
and adjusting the first sequencing result according to the new corresponding relation to obtain a second sequencing result.
In an embodiment, the transfer information is obtained by identifying a microwave signal with a moving position through a reading device of the electronic tag, and judging the transfer position through signal analysis;
the transfer information of the target sample can be acquired by monitoring the target sample in real time.
In an embodiment, the original target bit to be transferred is released through a reset function in the electronic tag.
The beneficial effects of the above technical scheme are: and re-acquiring the new corresponding relation of the corresponding first electronic tag, and eliminating the first electronic tag corresponding to the target sample to be transferred, so that the reduction of confusion on data is facilitated, and a second sequencing result is accurately acquired.
The invention provides a management method for sample sequencing in a laboratory, which further comprises the following steps after a second sequencing result is stored and displayed:
acquiring a transfer placement position of the target sample based on the transfer information;
determining the position attribute and the position environment of the transfer placement position based on a laboratory sample storage database, and simultaneously determining the sample attribute of the target sample;
judging whether the target sample placed in the transfer placing position is qualified or not according to the position attribute, the position environment and the sample attribute;
if the second sorting result is qualified, keeping the second sorting result unchanged;
and if not, pushing new information to be placed related to the target sample, adjusting the second sorting result to obtain a third sorting result, and displaying and storing the third sorting result.
In an embodiment, the location attribute and the location environment are drawn up according to a specific laboratory environment, and the location attribute and the location environment can be changed in different seasons and different temperatures;
the position attribute and the environment attribute can be determined according to the distance between the current target sample and the adjacent target sample;
In this embodiment, the display and the saving may be performed based on a display screen and stored based on a memory.
The beneficial effect of above-mentioned scheme is: through the qualification of the detection sample, a lot of manual procedures are reduced, and the quality control of the laboratory sample is well guaranteed.
The invention provides a management method for sample sequencing in a laboratory, which further comprises the following steps in the process of monitoring the transfer information of a target sample in a target area:
determining a target sample to be transferred according to a transfer instruction input by a laboratory worker;
detecting whether the target sample to be transferred is qualified or not, and monitoring and acquiring transfer information of the target sample to be transferred in a target area if the target sample to be transferred is qualified;
otherwise, storing the target sample to be transferred to an idle area, and performing first alarm reminding;
wherein, the step of detecting whether the target sample to be transferred is qualified comprises the following steps:
collecting a sample of the target sample to be transferred;
based on n preset measurement indexes, the sample samples are measured one by one, and a first measurement result w1 ═ { w1,w2,...,wnIn which wnThe first measurement result corresponding to the nth measurement index is represented;
Determining a first integrated weight value S1 for the sample thumbnail based on the first measurement;
S1＝w1β1+w2β2+...+wnβn；
wherein, betanRepresents an index weight factor corresponding to the nth measurement index, and beta1+β2+...+βn＝1；
Sorting the N measurement indexes from large to small based on the index occupation ratio to obtain second measurement results w2 ═ w { corresponding to the first N measurement indexes21,w22,...,w2NIn which w2NThe second measurement result corresponding to the Nth measurement index is represented;
determining a second integrated weight value S2 for the sample thumbnail based on the second measurement;
S2＝w21β21+w22β22+...+w2Nβ2N；
wherein, beta2NRepresents an index weight factor corresponding to the Nth measurement index, and beta21+β22+...+β2N＜1；
Determining a difference between the first and second integrated weight values S1 and S2;
when the difference value is smaller than a preset value, judging that the sample hand sample is qualified, and executing a second alarm prompt;
and when the difference is not less than the preset value, judging that the sample small sample is unqualified, and executing third alarm reminding.
In one embodiment, the branch instruction is based on the logical operation of the target sample in the branch, and the branch instruction is executed when the branch condition is satisfied.
In an embodiment, a branch instruction is typically a jump within the home address segment, which may be an instruction to branch a chemical sample or class.
In this embodiment, the measurement indicator may be related to the analyte of the sample, such as a physical property, a chemical property, and the like.
In this embodiment, the idle region may be a region where a rejected sample is processed.
In this embodiment, the preset value may be set manually, and the value range is [0, 5 ].
In this embodiment, the second alarm prompt and the third alarm prompt may be one or a combination of voice, light, vibration, and the like.
The beneficial effect of above-mentioned scheme: the n set measuring indexes are compared with the comprehensive weight value, so that whether the sample is qualified or not is judged, the workload is saved, the inspection period is shortened, and meanwhile, the n set measuring indexes are reminded through alarming, and timely processing is facilitated.
The invention provides a management method for sample sequencing in a laboratory, which comprises the following steps of in the process of reading a sample body of a target sample and electronic tags on target positions in a one-to-one correspondence manner:
sending a first connection protocol to a first electronic tag on a sample body of the target sample, and reading first electronic information of the first electronic tag;
meanwhile, a second connection protocol is sent to a second electronic tag on a target position corresponding to the target sample one by one, and second electronic information of the second electronic tag is read;
When the first electronic information and/or the second electronic information are not read, monitoring the body information of the sample body of the target sample, and simultaneously monitoring the bit information of the corresponding target bit;
optimizing the first sorting result according to the body information and the bit information;
wherein the body information includes: the shape information of the sample body, the color information of the sample body and the unique identification information of the sample body;
the bit information includes: the size of the slot position for placing the target position, the shape of the slot position for placing the target position and the unique identification information of the target position.
In an embodiment, the first connection protocol is an access protocol, and information is transmitted over a wide area network link.
In this embodiment, the unique identification code can be a paper two-dimensional code pasted on the target position and the sample body, thereby avoiding damage of the electronic tag and failure to timely acquire related information, which results in a wrong sorting.
The beneficial effect of above-mentioned scheme is: the unique identification information of the target is determined by acquiring the body information and the bit information, so that the information is prevented from being overlapped or lost to cause unnecessary loss.
The invention provides a management method for sample sequencing in a laboratory, which comprises the steps of collecting the initial sample mass M of a target sample, and measuring the mass change information of the target sample in a preset time period through D pressure sensors of target positions corresponding to the target sample one by one;
Calculating the average consumption efficiency mu of the target sample in a preset time period according to the quality change information;
wherein m represents the sampling times of the target sample in a preset time period; mjiThe pressure value measured by the jth pressure sensor after the ith target sample is sampled is represented; mji+1The pressure value measured by the jth pressure sensor after the ith +1 time of sampling the target sample is represented; t isi+1The sampling time interval between the ith and the (i + 1) th sampling of the target sample is represented;Mj1represents the pressure value measured by the jth pressure sensor after the 1 st sampling of the target sample; t is1Representing the sampling time interval between no sampling and the sampling of the target sample at the 1 st time;
acquiring a historical use time set of the target sample, and determining a frequent use stage of the target sample according to the historical use time set;
and adjusting and reminding the current position of the target sample according to the frequent use stage and the average consumed power.
In an embodiment, the current position of the target sample is adjusted and reminded, and the reminding is realized through a timer attached to a pressure sensor of the target position.
The time aggregation in this embodiment may be implemented by a data store.
In this embodiment, for example, the frequent use stage of the sample a is 3-4 months, and at this time, when 3-4 months are reached, the sample a can be moved to a position convenient for taking, so that the management efficiency is improved.
The beneficial effect of above-mentioned scheme is: through obtaining the preset consumption efficiency in the preset time period and then the frequent use stage in the time period, the comparison is convenient to make, and the position of the experimental sample is adjusted in time.
The invention provides a management method for sample sequencing in a laboratory, which comprises the following steps of judging whether a target sample placed in a transfer placing position is qualified or not according to the position attribute, the position environment and the sample attribute:
calibrating a current transfer placement position;
based on a placing position space table, carrying out sample area division on a laboratory to obtain p sample areas, and calibrating the current transfer placing position in a corresponding first sample area;
determining an environmental attribute X of the first sample region;
determining a first relationship y1 of the current transfer placement bit and the first sample region;
determining the current transfer placement bit and the secondSecond relationship y2 ═ y { y of adjacent placement bits in a sample region21,y22,y23,y24}；
Wherein, y 21Forward placement bit information indicating the current transfer placement bit; y is22Rear placement bit information representing the current transfer placement bit; y is23Left placement bit information representing the current transfer placement bit; y is24Right placement bit information representing the current transfer placement bit;
according to the first relation and the second relation, calculating the association degree Y of the current transfer placement position based on the first sample area;
wherein H (y1) represents a position attribute correlation function based on the first relationship y 1; h (y2) represents a position attribute association function based on a second relationship y 2; y represents current transfer placement bit information; e represents a natural constant;
calculating the matching degree Z of the target sample corresponding to the transfer placement and the current placement position;
wherein H' (z0, z1, z2, z3, z4) represents a sample property association function based on the target sample z0 at the current placement position and the target sample z1 at the front placement position, the target sample z2 at the rear placement position, the target sample z3 at the left placement position, and the target sample z4 at the right placement position;
calculating a comprehensive placement value R of the target sample placed on the current transfer placement position according to the environment attribute X, the association degree Y and the matching degree Z;
R＝a1X+a2Y+a3Z；
Wherein a1 represents the environmental factor of the first sample area; a2 denotes a position association factor based on the current placement bit; a3 denotes a sample correlation factor based on the current placement position; and a1+ a2+ a3 is 1;
when the R is larger than a standard placing value, judging that the target sample placed on the transfer placing position is qualified;
otherwise, judging that the target sample placed on the transfer placing position is unqualified, and executing fourth alarm reminding.
In an embodiment, the sample region is divided by sample class.
The beneficial effect of above-mentioned scheme is: the relevance degree of the current transfer placing position is conveniently determined by calibrating the current transfer placing position to the corresponding first sample area, the matching degree is conveniently obtained by calculating the relation between the target sample of the current transfer placing position and the target samples in different directions, and the comprehensive placing value is calculated based on the environment attribute, the relevance degree and the matching degree, so that the qualified reliability of the target sample is conveniently increased, and the troubleshooting work of laboratory workers is reduced.
The present invention provides a management system for sample sequencing in a laboratory, as shown in fig. 2, comprising:
the reading module is used for reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and acquiring a first sequencing result of the target sample;
The monitoring module is used for monitoring the transfer information of the target sample in the target area, and adjusting the first sequencing result based on the transfer information to obtain a second sequencing result;
and the display module is used for storing and displaying the second sequencing result.
In an embodiment, the display module may be an LCD1602 liquid crystal display.
The beneficial effect of above-mentioned scheme is: through electronic tags's accurate positioning, obtain the position condition of sample, fine solution present loaded down with trivial details operation, increased the accuracy of sample management, overcome the drawback that exists at present, make laboratory sample management efficiency higher.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (9)
1. A method for managing sample ordering in a laboratory, comprising:
reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and obtaining a first sequencing result of the target sample;
Monitoring transfer information of the target sample in a target area, and adjusting the first sequencing result based on the transfer information to obtain a second sequencing result;
and saving and displaying the second sequencing result.
2. The method of claim 1, wherein the step of obtaining a first ordering of the target samples comprises:
the method comprises the steps of inductively reading a first electronic tag arranged on a sample body of a target sample;
sensing and reading a second electronic tag of the sample body, which is placed at a corresponding target position;
establishing a one-to-one corresponding relation between the first electronic tag and the second electronic tag;
and acquiring a first sequencing result of the target sample according to the one-to-one correspondence.
3. The management method according to claim 1, wherein the adjusting the first sorting result based on the transition information and the obtaining the second sorting result comprises:
adjusting the electronic information in the second electronic tag of the transfer placement position based on the transfer information;
the original corresponding relation between a first electronic tag corresponding to a target sample to be transferred and a second electronic tag corresponding to an original target position is released, and a new corresponding relation between the second electronic tag corresponding to the transfer placement position and the first electronic tag corresponding to the target sample to be transferred is reestablished;
And adjusting the first sequencing result according to the new corresponding relation to obtain a second sequencing result.
4. The method of managing as set forth in claim 1, wherein after saving and displaying the second ranking result, further comprising:
acquiring a transfer placement position of the target sample based on the transfer information;
determining the position attribute and the position environment of the transfer placement position based on a laboratory sample storage database, and simultaneously determining the sample attribute of the target sample;
judging whether the target sample placed in the transfer placing position is qualified or not according to the position attribute, the position environment and the sample attribute;
if the second sorting result is qualified, keeping the second sorting result unchanged;
and if not, pushing new information to be placed related to the target sample, adjusting the second sorting result to obtain a third sorting result, and displaying and storing the third sorting result.
5. The method for managing as claimed in claim 1, wherein the monitoring of the transfer information of the target sample in the target area further comprises:
determining a target sample to be transferred according to a transfer instruction input by a laboratory worker;
Detecting whether the target sample to be transferred is qualified or not, and monitoring and acquiring transfer information of the target sample to be transferred in a target area if the target sample to be transferred is qualified;
otherwise, storing the target sample to be transferred to an idle area, and performing first alarm reminding;
wherein, the step of detecting whether the target sample to be transferred is qualified comprises the following steps:
collecting a sample of the target sample to be transferred;
based on n preset measurement indexes, the sample is sampledA one-to-one measurement is performed to obtain a first measurement w1 ═ w1,w2,...,wnIn which wnThe first measurement result corresponding to the nth measurement index is represented;
determining a first integrated weight value S1 for the sample thumbnail based on the first measurement;
S1＝w1β1+w2β2+...+wnβn；
wherein, betanRepresents an index weight factor corresponding to the nth measurement index, and beta1+β2+...+βn＝1；
Sorting the N measurement indexes from large to small based on the index occupation ratio to obtain second measurement results w2 ═ w { corresponding to the first N measurement indexes21,w22,...,w2NIn which w2NThe second measurement result corresponding to the Nth measurement index is represented;
determining a second integrated weight value S2 for the sample thumbnail based on the second measurement;
S2＝w21β21+w22β22+...+w2Nβ2N；
wherein, beta2NRepresents an index weight factor corresponding to the Nth measurement index, and beta 21+β22+...+β2N＜1；
Determining a difference between the first and second integrated weight values S1 and S2;
when the difference value is smaller than a preset value, judging that the sample hand sample is qualified, and executing a second alarm prompt;
and when the difference is not less than the preset value, judging that the sample small sample is unqualified, and executing third alarm reminding.
6. The method for managing as claimed in claim 1, wherein in the process of reading the sample body of the target sample and the electronic tag on the one-to-one corresponding target site, further comprising:
sending a first connection protocol to a first electronic tag on a sample body of the target sample, and reading first electronic information of the first electronic tag;
meanwhile, a second connection protocol is sent to a second electronic tag on a target position corresponding to the target sample one by one, and second electronic information of the second electronic tag is read;
when the first electronic information and/or the second electronic information are not read, monitoring the body information of the sample body of the target sample, and simultaneously monitoring the bit information of the corresponding target bit;
optimizing the first sorting result according to the body information and the bit information;
wherein the body information includes: the shape information of the sample body, the color information of the sample body and the unique identification information of the sample body;
The bit information includes: the size of the slot position for placing the target position, the shape of the slot position for placing the target position and the unique identification information of the target position.
7. The management method according to claim 1,
acquiring the initial sample mass M of the target sample, and measuring the mass change information of the target sample in a preset time period through D pressure sensors of target positions corresponding to the target sample one by one;
calculating the average consumption efficiency mu of the target sample in a preset time period according to the quality change information;
wherein m represents the sampling times of the target sample in a preset time period; mjiThe pressure value measured by the jth pressure sensor after the ith target sample is sampled is represented; mji+1The pressure value measured by the jth pressure sensor after the ith +1 time of sampling the target sample is represented; t isi+1The sampling time interval between the ith and the (i + 1) th sampling of the target sample is represented; mj1Represents the pressure value measured by the jth pressure sensor after the 1 st sampling of the target sample; t is1Representing the sampling time interval between no sampling and the sampling of the target sample at the 1 st time;
acquiring a historical use time set of the target sample, and determining a frequent use stage of the target sample according to the historical use time set;
And adjusting and reminding the current position of the target sample according to the frequent use stage and the average consumed power.
8. The management method according to claim 4, wherein the determining whether the target sample placed at the transfer placement site is qualified according to the location attribute, the location environment, and the sample attribute comprises:
calibrating a current transfer placement position;
based on a placing position space table, carrying out sample area division on a laboratory to obtain p sample areas, and calibrating the current transfer placing position in a corresponding first sample area;
determining an environmental attribute X of the first sample region;
determining a first relationship y1 of the current transfer placement bit and the first sample region;
determining a second relationship y2 ═ y { y } of the current transfer placement bit and neighboring placement bits in the first sample region21,y22,y23,y24}；
Wherein, y21Forward placement bit information indicating the current transfer placement bit; y is22Rear placement bit information representing the current transfer placement bit; y is23Left placement bit information representing the current transfer placement bit; y is24Right placement bit information representing the current transfer placement bit;
According to the first relation and the second relation, calculating the association degree Y of the current transfer placement position based on the first sample area;
wherein H (y1) represents a position attribute correlation function based on the first relationship y 1; h (y2) represents a position attribute association function based on a second relationship y 2; y represents current transfer placement bit information; e represents a natural constant;
calculating the matching degree Z of the target sample corresponding to the transfer placement and the current placement position;
wherein H' (z0, z1, z2, z3, z4) represents a sample property association function based on the target sample z0 at the current placement position and the target sample z1 at the front placement position, the target sample z2 at the rear placement position, the target sample z3 at the left placement position, and the target sample z4 at the right placement position;
calculating a comprehensive placement value R of the target sample placed on the current transfer placement position according to the environment attribute X, the association degree Y and the matching degree Z;
R＝a1X+a2Y+a3Z；
wherein a1 represents the environmental factor of the first sample area; a2 denotes a position association factor based on the current placement bit; a3 denotes a sample correlation factor based on the current placement position; and a1+ a2+ a3 is 1;
when the R is larger than a standard placing value, judging that the target sample placed on the transfer placing position is qualified;
Otherwise, judging that the target sample placed on the transfer placing position is unqualified, and executing fourth alarm reminding.
9. A management system for sample ordering in a laboratory, comprising:
the reading module is used for reading a sample body of a target sample and electronic tags on target positions in one-to-one correspondence, and acquiring a first sequencing result of the target sample;
the monitoring module is used for monitoring the transfer information of the target sample in the target area, and adjusting the first sequencing result based on the transfer information to obtain a second sequencing result;
and the display module is used for storing and displaying the second sequencing result.
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Denomination of invention: A management method and system for sample sorting in laboratory Effective date of registration: 20220117 Granted publication date: 20210427 Pledgee: Beijing ustron Tongsheng financing Company limited by guarantee Pledgor: BEIJING DYNAFLOW EXPERIMENT TECHNOLOGY Co.,Ltd. Registration number: Y2022990000027 |