CN111855989A - Sample rack, sample loading mechanism and sample analyzer - Google Patents
Sample rack, sample loading mechanism and sample analyzer Download PDFInfo
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- CN111855989A CN111855989A CN201910343690.3A CN201910343690A CN111855989A CN 111855989 A CN111855989 A CN 111855989A CN 201910343690 A CN201910343690 A CN 201910343690A CN 111855989 A CN111855989 A CN 111855989A
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- 230000007246 mechanism Effects 0.000 title claims description 22
- 239000002184 metal Substances 0.000 claims abstract description 111
- 230000003068 static effect Effects 0.000 claims abstract description 50
- 230000005611 electricity Effects 0.000 claims description 30
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000006243 chemical reaction Methods 0.000 description 11
- 239000003153 chemical reaction reagent Substances 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- 238000004140 cleaning Methods 0.000 description 7
- 238000011534 incubation Methods 0.000 description 5
- 238000012546 transfer Methods 0.000 description 5
- 238000007885 magnetic separation Methods 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 239000012790 adhesive layer Substances 0.000 description 3
- 238000003018 immunoassay Methods 0.000 description 3
- 239000007769 metal material Substances 0.000 description 3
- 238000005299 abrasion Methods 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000000504 luminescence detection Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
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Abstract
The application discloses sample frame, including the support body and install the static-removing subassembly on this support body, the support body has the sample seat that is used for placing the sample container, the static-removing subassembly has the metal shrapnel that is used for leading away the static of placing the sample container in the sample seat, the metal shrapnel has first elastic contact portion and the second contact portion that is connected, first elastic contact portion is used for elastic contact to place the outer wall of the sample container in the sample seat, the second contact portion is used for with the electrically conductive brush electric connection of ground connection, so that the static on the sample container of placing in the sample seat can be conducted to first elastic contact portion, second contact portion and electrically conductive brush in proper order. The application provides a sample frame is used for elastic contact sample container through the first elastic contact portion with the metal shrapnel in the subassembly that destatics, and the second contact portion of metal shrapnel can be connected with the electrically conductive brush of ground connection to make static on the sample container can lead away through first elastic contact portion, second contact portion and electrically conductive brush in proper order.
Description
Technical Field
The application relates to the field of medical equipment, in particular to a sample rack, a sample loading mechanism and a sample analyzer.
Background
In sample analysis appearance, especially chemiluminescence immunoassay appearance, the sample container can have the friction to the container wall in packing and use, and the sample container is non-metallic material basically, produces static easily, and static on the container wall can produce interference signal to the electric capacity that the liquid level detected, leads to electric capacity fluctuation great to lead to the liquid level to detect the inefficacy.
In the prior art, the sample container wall is directly brushed by a grounded conductive brush to conduct away static electricity on the sample container wall. The inventors, using a prior art chemiluminescent analytical instrument, found the following drawbacks: because the sample container is generally placed on the sample frame, the upper end surface of the sample container must be higher than the upper end surface of the conductive brush, otherwise the conductive brush is easy to brush the opening part of the sample container, the conductive brush is easy to stick a sample, and the risk of sample cross contamination exists.
Disclosure of Invention
The application provides a sample rack, a sample loading mechanism and a sample analyzer capable of conducting away static electricity on sample containers with different heights.
The first aspect of the application provides a sample holder, including the support body and install the static-removing subassembly on this support body, the support body has the sample seat that is used for placing the sample container, the static-removing subassembly has the metal shrapnel that is used for leading away the static of placing the sample container in the sample seat, the metal shrapnel has first elastic contact portion and the second contact portion that is connected, first elastic contact portion is used for elastic contact, especially hugs closely and places the outer wall of the sample container in the sample seat, the second contact portion is used for with the electrically conductive brush electric connection of ground connection to make place the static energy on the sample container in the sample seat be conducted in proper order to first elastic contact portion, second contact portion and electrically conductive brush.
In an advantageous embodiment of the sample rack of the present application, the first resilient contact portion may have at least one convex section that is convex in the direction of the vertical central axis of the respective sample holder, in order to contact an outer wall of a sample container placed in the sample holder.
In an advantageous embodiment of the sample holder according to the application, the at least one convex section can be of trapezoidal or circular-arc shape.
In an advantageous embodiment of the sample rack of the present application, the at least one protruding section may be arranged close to the opening of the sample holder, so that the at least one protruding section can contact the outer wall of sample containers of different heights placed in the sample holder.
In an advantageous embodiment of the sample rack of the present application, the first resilient contact portion may be arranged inside the sample holder and the second contact portion may be located outside the sample holder.
In an advantageous embodiment of the sample rack of the present application, the bottom of the sample holder may be provided with through holes, the number of the through holes corresponds to the number of the first elastic contact portions, and the first elastic contact portions extend into the sample holder through the through holes.
In an advantageous embodiment of the sample rack of the present application, the static discharge assembly may further have at least one conductive member fixed to the rack body, and the second contact portion is configured to be electrically connected to the conductive brush via the at least one conductive member, so that static electricity on the sample holder can be sequentially conducted to the first elastic contact portion, the second contact portion, the at least one conductive member, and the conductive brush.
In an advantageous embodiment of the sample rack of the present application, the sample rack may further include a metal plate, the rack body and the static discharge assembly are fixedly disposed on the metal plate, wherein the second contact portion is fixed on the metal plate, a portion of the conductive member is disposed on the metal plate, and another portion of the conductive member is capable of contacting the conductive brush.
In an advantageous embodiment of the sample holder of the present application, the metal plate may have a first surface, a second surface and a mounting hole penetrating through the metal plate, the holder body is fixed on the first surface, the second contact portion is fixed on the second surface and the first elastic contact portion extends into the corresponding sample holder through the mounting hole.
In an advantageous embodiment of the sample rack of the present application, the side wall of the sample holder may have at least one cutout, the number of cutouts corresponding to the number of first elastic contacts, which protrude through the cutouts into the sample holder.
In an advantageous embodiment of the sample rack of the present application, the number of the sample holders may be the same as the number of the metal spring pieces, and each sample holder is provided with one metal spring piece.
In an advantageous embodiment of the sample rack of the present application, each of the metal elastic pieces may have two first elastic contact portions, and the two first elastic contact portions of each of the metal elastic pieces are respectively connected to two sides of the second contact portion of the metal elastic piece. Further advantageously, each first resilient contact portion of each metal dome may have at least one convex section, wherein the convex section of one first resilient contact portion and the convex section of the other first resilient contact portion are convex toward each other and have a minimum distance from each other that is smaller than an outer diameter of the sample container, so that the sample container can be clamped.
A second aspect of the present application provides a sample loading mechanism comprising a grounded base plate, a conductive brush and a sample holder according to the first aspect of the present application, the sample holder being supported on the base plate and the conductive brush being fixed to the base plate. Advantageously, one end of the conductive brush may be fixed to the base plate, and the other end of the conductive brush may be located between the sample holder and the base plate, the sample holder being rotatable relative to the base plate.
A third aspect of the present application provides a sample analyzer, in particular a chemiluminescent immunoassay analyzer, comprising a sample loading mechanism according to the second aspect of the present application for loading a sample.
The application provides a sample frame is used for elastic contact, especially hugs closely the outer wall of sample container through the first elastic contact portion of the metal shrapnel in the subassembly that destatics, and the second elastic part of metal shrapnel can be connected with the electrically conductive brush of ground connection, thereby make static on the sample container can be conducted to first elastic contact portion in proper order, second contact portion and electrically conductive brush, electrically conductive brush and sample container direct contact are avoided in the setting of this metal shrapnel, make not co-altitude sample container homoenergetic and first elastic contact portion, thereby a sample frame that can lead static on the sample container of co-altitude away is provided.
Drawings
In order to more clearly illustrate the technical solution of the present application, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without inventive labor.
FIG. 1 is a schematic view of a sample loading mechanism provided in an embodiment of the present application;
FIG. 2 is an enlarged partial schematic view of a micro and macro sample containers housed in a sample rack of the sample loading mechanism of FIG. 1;
Fig. 3 is an exploded view of a sample holder and a metal dome of a sample rack according to an embodiment of the present disclosure;
FIG. 4 is a schematic view of a sample holder of a sample rack according to an embodiment of the present disclosure, in which the metal dome is removed;
fig. 5 is a schematic view of a first embodiment of a metal dome according to the present application, wherein the metal dome has only one first elastic contact portion;
FIG. 6 is a schematic view of a second embodiment of a metal dome of the present application, wherein a convex section of a first elastic contact portion of the metal dome is disposed close to an opening of a sample holder;
fig. 7 is a schematic view of a third embodiment of a metal dome according to the present application, wherein a plurality of bumps are disposed on a first elastic contact portion of the metal dome;
fig. 8 is a schematic view of a fourth embodiment of a metal dome of the present application, wherein a second contact portion of the metal dome is connected to a conductive brush through a conductive member;
FIG. 9 is a schematic view of another embodiment of a sample holder of the present application, wherein the sample holder has a metal plate, and the second contact portion of the metal dome is connected to the conductive brush through the metal plate and the conductive member;
fig. 10 is a schematic diagram of a sample analyzer provided in an embodiment of the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings). In the description of the present application, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present application and for simplicity in description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be considered as limiting the present application.
In this application, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
Referring to fig. 1 and 2, a sample loading mechanism 100 provided in an embodiment of the present application is shown, which includes a sample rack 10, a grounded base plate 20, and a conductive brush 30. The sample rack 10 is used for accommodating sample containers and is supported on the bottom plate 20, and the conductive brush 30 is fixed on the bottom plate 30.
In a preferred embodiment, the sample rack 10 can rotate relative to the bottom plate 20, and the conductive brush 30 is fixedly disposed on the bottom plate 20, so that when the sample rack 10 rotates relative to the bottom plate 20, the conductive brush 30 can guide static electricity on a sample container placed on the sample rack 10 to the ground, thereby removing the static electricity from the sample container. It will be appreciated that the sample loading structure 100 may further comprise a sample gear plate 50, the sample gear plate 50 being disposed between the sample rack 10 and the base plate 20, the sample gear plate 50 being configured to engage with other components to rotate the sample rack 10.
As shown in fig. 2, different types of sample containers can be placed on the sample rack 10 to satisfy the sample testing of different sample volumes. When a micro sample, such as a peripheral blood sample, is required to be tested, the micro sample may be contained in a sample container with a lower height, for convenience of description, the micro sample container 41 is defined herein, and the micro sample container 41 is generally suspended on the sample rack 10 due to the lower height of the micro sample container 41. When a constant sample, for example, a venous blood sample, is to be tested, the constant sample may be contained in a sample container with a relatively high height, and for convenience of description, the constant sample container 42 is defined herein as a constant sample container 42, the height of the constant sample container 42 is relatively high compared with the height of the micro sample container 41, and the bottom 111 of the constant sample container 42 is generally capable of contacting the sample rack 10.
In one embodiment, referring to fig. 3 together, the sample rack 10 includes a rack body 1 and a static discharge assembly 2 mounted on the rack body 1, the rack body 1 has a plurality of sample holders 11 for holding sample containers, the static discharge assembly 2 has a metal elastic sheet 210 for conducting away static electricity of the sample containers held in the sample holders 11, the metal elastic sheet 210 has a first elastic contact portion 211 and a second contact portion 212 connected with each other, the first elastic contact portion 211 is used for elastically contacting, especially tightly contacting or clamping, outer walls of the sample containers held in the sample holders 11, and the second contact portion 212 is used for electrically connecting with the grounded conductive brush 30, so that the static electricity of the sample containers held in the sample holders 11 can be sequentially conducted to the first elastic contact portion 211, the second contact portion 212 and the conductive brush 30. In other words, the sample container placed on the sample rack 10 is not directly contacted with the conductive brush 30, but the first elastic contact portion 211 of the metal spring 210 is contacted with the outer wall of the sample container, and the second contact portion 212 of the metal spring 210 is electrically connected to the conductive brush 30, so that the static electricity of the sample container is conducted to the conductive brush 30 through the metal spring 210 to remove the static electricity. In other words, regardless of whether the sample container is the micro sample container 41 or the macro sample container 42, the metal elastic piece 210 can contact the outer wall of the sample container, and then the static electricity of the sample container is conducted to the conductive brush 30 through the first elastic contact portion 211 and the second contact portion 212, so that the conductive brush 30 is prevented from directly contacting the sample container, and the liquid level of the sample container is prevented from being polluted by the conductive brush 30.
In one embodiment, referring to fig. 4, the rack 1 has a plurality of sample holders 11 for holding sample containers. The plurality of sample holders 11 may be divided into, for example, four groups of sample holders 11, the four groups of sample holders 11 forming a circle around them, only one group of sample holders 11 being shown in fig. 4. Each sample holder 11 has a bottom 111 and a sidewall 112, the sidewall 112 surrounds the bottom 111 to form a receiving space 113, and an end of the sample holder 11 opposite to the bottom 111 forms an opening for placing a sample container in the receiving space 113. It will be appreciated that the side wall is provided with a notch 114, and an identification code scanner can scan an identification code, such as a bar code, of a sample container located in the sample holder 11 through the notch 114.
In an embodiment, the number of the sample holders 11 may be the same as the number of the metal elastic pieces 210, and each sample holder 11 is provided with one metal elastic piece 210. In other words, each sample holder 11 is provided with a metal spring 210, so that static electricity on the sample container in each sample holder 11 can be guided to the conductive brush 30 through the metal spring 210, and further to the ground. Of course, in other embodiments, the number of the metal elastic pieces 210 may not correspond to the number of the sample holders 11, in other words, the number of the metal elastic pieces 210 may be smaller than the number of the sample holders 11.
Alternatively, as shown in fig. 3, one metal dome 210 may have two first elastic contact portions 211 capable of elastically contacting the sample container, and the two first elastic contact portions 211 are respectively connected to two sides of the corresponding second contact portion 212. Specifically, one metal spring 210 may be formed by bending a sheet-shaped conductive metal material, and the metal spring 210 is substantially U-shaped. In other words, since the two first elastic contact portions 211 are respectively connected to two sides of the corresponding second contact portion 212, a space between the two first elastic contact portions 211 is formed to form the accommodating space 213, and the space is slightly smaller than the outer diameter of the sample container. When the two first elastic contact portions 211 are inserted into the receiving space 113 of the sample holder 11 and a sample container is received in the sample holder 11, the two first elastic contact portions 211 of the metal elastic piece 210 in the sample holder can elastically contact the outer walls of the two sides of the sample container to clamp the sample container in the formed receiving space 213. Therefore, not only can the static electricity of the sample container be conducted away by the two first elastic contact portions 211 of the metal elastic sheet 210, but also the sample container can be better fixed in the sample holder 11 by the two first elastic contact portions 211 elastically abutting against the outer wall of the sample container.
Of course, in other embodiments, as shown in fig. 5, the number of the first elastic contact portions 231 of one metal spring 210 may also be one, in other words, the first elastic contact portions 231 and the second elastic contact portions 232 form an L shape, that is, one metal spring 210 may be formed by bending a sheet-shaped conductive metal material, and the metal spring 210 is substantially L-shaped. In addition, in the case that one metal spring 210 has only one first elastic contact portion, the structure of the first elastic contact portion 211 may be annular, and correspondingly, the second contact portion 212 is also annular, the first elastic contact portion 211 is connected to the second contact portion 212 in a surrounding manner, and forms an accommodating space 213, and when a sample container needs to be placed in the sample holder 11, the sample container is located in the accommodating space 213.
In addition, one metal dome 210 may also have more than three first elastic contact portions 211.
Next, the structure of the first elastic contact portion 211 of the metal dome 210 according to the present invention will be described in detail with reference to the accompanying drawings.
In one embodiment, as shown in fig. 3 and 6, the first resilient contact portion 211 has at least one convex section 2112, the at least one convex section 2112 being convex in the direction of the vertical central axis X1 of the respective sample holder 11, so as to contact, in particular to abut, the outer wall of a sample container placed in the sample holder 11.
It is understood that, in an embodiment, one metal dome 210 may have two first elastic contact portions 211, and the convex section 2112 of one first elastic contact portion 211 and the convex section 2112 of the other first elastic contact portion 211 of the metal dome 210 are protruded toward each other and have a minimum distance therebetween smaller than the outer diameter of the sample container so as to elastically contact and grip the corresponding sample container. That is, the protruding sections 2112 of the two first elastic contact portions 211 are arranged oppositely, so that the distance between the two first elastic contact portions 211 is further reduced, the outer wall of the sample container can be more tightly abutted by the protruding sections 2112 of the two first elastic contact portions 211, and the sample container can be better fixed in the sample holder 11. Further, since only the convex section 2112 of the first resilient contact portion 211 is in close contact with the outer wall of the sample container, abrasion of the outer wall of the sample container is also reduced.
Of course, in other embodiments, one metal dome 210 may have only one first elastic contact portion 211, as shown in fig. 5, in which case, only one first elastic contact portion 211 may also have at least one convex section 2112 for contacting the outer wall of the corresponding sample container, which enables the contact area between the sample container and the first elastic contact portion 211 to be small, and avoids abrasion of the outer wall of the sample container.
In one embodiment, the at least one raised section 2112 is positioned adjacent to the opening of the sample holder 11 so that the at least one raised section 2112 can contact the exterior wall of a sample container of a different height, such as a micro sample container 41 or a macro sample container 42, placed in the sample holder. As shown in fig. 6, the micro sample container 41 and the macro sample container 42 are respectively sandwiched between two convex portions 2112 of the metal dome 210. In other words, since the convex portion 2112 is provided close to the opening of the sample holder 11, even if the height of the micro sample container 41 is small, the convex portion 2112 can closely contact the outer wall of the micro sample container 41, thereby conducting away static electricity on the micro sample container 41.
In an embodiment, the at least one convex segment 2112 may be a protrusion protruding from the first elastic contact portion 211 with a straight shape, such as a trapezoid or a circular arc, wherein the trapezoid or the circular arc facilitates the sample container to enter the receiving space 213 formed by the two first elastic contact portions of the metal dome. For example, as shown in fig. 3, the first resilient contact portion 211 may have a first straight section 2111, a convex section 2112, and optionally a second straight section 2113 connected in series. The first flat section 2111 is connected to the second contact portion 212. The convex portion 2112 may have a first connection arm 2112a, a second connection arm 2112b, and a third connection arm 2112c, which are sequentially bent and connected, and be configured in a trapezoidal shape, in which the first connection arm 2112a and the third connection arm 2112c are oppositely disposed. In other words, the first elastic contact portion 211 is substantially in a shape of a "bow", and the first elastic contact portion 211 of the "bow" is configured such that the distance between the convex sections 2112 of the two first elastic contact portions 211 of one metal dome 210 is the smallest distance between the two first elastic contact portions 211 of the metal dome 210, and the smallest distance is smaller than the outer diameter of the sample container, while the distance between the two first flat sections 2111 is larger than the outer diameter of the sample container, and the distance between the two second flat sections 2113 is larger than the outer diameter of the sample container, in other words, when the sample container is clamped in the metal dome 210, only the two convex sections 2112 contact with the outer wall of the sample container, so that the contact area between the sample container and the first elastic contact portions 211 is small, and the outer wall of the sample container is prevented from being worn.
Of course, in other embodiments, as shown in fig. 7, at least one of the convex segments may be a plurality of convex points 2115 protruding from the first elastic contact portion 211 in a straight shape at intervals. In other words, the first elastic contact portion 211 has a third straight portion 2114 and a plurality of convex points 2115, and the plurality of convex points 2115 are provided to protrude from the third straight portion 2114 along the length extension direction of the third straight portion 2114 and protrude toward the vertical central axis X1 of the sample holder 11. When the metal dome 210 has two first elastic contact portions 211, a distance between the opposite protruding points on the two first elastic contact portions is smaller than an outer diameter of the sample container, so that the two first elastic contact portions can be in close contact with the outer wall of the sample container to conduct away static electricity on the sample container.
Next, the electrical connection relationship between the second contact portion 212 of the metal spring 210 and the conductive brush 30 is described in detail with reference to the drawings.
In one embodiment, as shown in fig. 8, the first elastic contact portion 211 is disposed inside the sample holder 11 and the second contact portion 212 is disposed outside the sample holder 11, so that the second contact portion 212 can contact the conductive brush 30 when the sample holder 10 rotates relative to the bottom plate 20, to conduct static electricity on the sample container to the first elastic contact portion 211, the second contact portion 212, and the conductive brush 30 in sequence. In other words, the second contact portion 212 can directly contact the conductive brush 30 to electrically connect the second contact portion 212 and the conductive brush 30. It can be understood that the bottom 111 of the sample holder 11 may be provided with through holes, the number of the through holes corresponds to the number of the first elastic contact portions 211, and the first elastic contact portions 211 extend into the sample holder 11 through the through holes. In addition, the second contact portion 212 may be spaced apart from the sample holder 11, and in particular, the second contact portion 212 may be located below the bottom 111 of the sample holder 11 and spaced apart from the bottom 111 of the sample holder 11 by a certain distance so that the conductive brush 30 is in contact with the second contact portion 212, so that static electricity on the sample container is sequentially transferred to the first elastic contact portion 211, the second contact portion 212, the conductive brush 30, and the ground, thereby eliminating static electricity on the outer wall of the sample container.
In another embodiment, as shown in fig. 3, the static electricity removing assembly 2 further has at least one conductive member 220 fixed on the frame body 1, and the second contact portion 212 is used to electrically connect with the conductive brush 30 through the at least one conductive member 220, so that the static electricity on the sample holder 11 can be sequentially conducted to the first elastic contact portion 211, the second contact portion 212, the at least one conductive member 220 and the conductive brush 30. In other words, the second contact part 212 is indirectly electrically connected to the conductive brush 30 via the conductive member 220, so that the static electricity on the first elastic contact part 211 is sequentially transferred to the second contact part 212, the conductive member 220, the conductive brush 30, the bottom plate 20 and the ground. Specifically, the number of the conductive members 220 may be four, one conductive member 220 corresponds to one group of the sample holders 11, for example, a part of one conductive member 220 is electrically connected to each of the second contact portions 212 corresponding to one group of the sample holders, and another part of the conductive member 220 extends out of the group of the sample holders 11 to be able to contact with the conductive brush. The second contact portion 212 and the conductive brush 30 are electrically connected through the conductive members 220, so that the frame body 1 rotates one turn relative to the bottom plate 20, the conductive brush 30 can sequentially contact four conductive members 220, and each time the conductive brush 30 contacts one conductive member 220, the conductive brush 30 can conduct the static electricity on all the second contact portions 212 electrically connected with the conductive members 220 to the ground, so that the static electricity of a plurality of sample containers can be eliminated simultaneously and rapidly. Of course, in other embodiments, all sample holders 11 may correspond to one conductive member 220, that is, the second contact portions 212 of all metal elastic sheets 210 are electrically connected to the same conductive member 220, or a group of sample holders 11 may correspond to a plurality of conductive members 220, for example, one sample holder 11 may correspond to one conductive member 220.
In another embodiment, not shown, the second contact portion 212 may be embedded in the bottom 111 of the sample holder 11, the number of the conductive members 220 is multiple, one conductive member 220 corresponds to one or more metal elastic sheets 210, a part of the conductive member 220 is embedded in the bottom 111 of the sample holder 11 and abuts against the second contact portion 212, and another part of the conductive member 220 extends out of the sample holder 11 to be able to contact with the conductive brush. Specifically, the conductive elements 220 may be conductive pillars, one end of one conductive pillar extends into the bottom 111 of the sample holder 11 until abutting against the second contact portion 212, so as to realize an electrical connection relationship between the second contact portion 212 and the one conductive pillar, and the other end of the conductive pillar extends out of the bottom 111 of the sample holder 11 and is located below the bottom 111 of the sample holder 11. Optionally, the other end of the conductive post can be close to the bottom plate, so that the conductive brush can be conveniently contacted with the conductive post.
In another embodiment, referring to fig. 9, the electrical connection relationship between the second contact portion 212 and the conductive member 220 may further be: the sample holder 10 further includes at least one metal plate 3, the holder body 1 and the static discharge assembly 2 are fixedly disposed on the metal plate 3, wherein the second contact portion 212 is fixed on the metal plate 3, one part of the conductive member 220 is disposed on the metal plate 3, and the other part of the conductive member 220 can contact the conductive brush 30.
Optionally, the metal plate 3 has a first surface 31, a second surface 32 and a plurality of mounting holes 33 penetrating through the metal plate 3, the frame body 1 is fixed on the first surface 31, the second contact portion 212 is fixed on the second surface 32, and the corresponding first elastic contact portion 211 extends into the corresponding sample holder 11 through the mounting hole 33.
Specifically, the number of the metal plates 3 may be four, and one metal plate 3 corresponds to one group of the sample holders 11. The second contact portion 212 is attached to the metal plate 3 in a planar manner, so as to increase the electrical connection area between the second contact portion 212 and the metal plate 3 and ensure good electrical connection therebetween. The second contact portions 212 of the sample holders 11 are electrically connected to a conductive member 220 via the metal plate 3. While the metal plate 3 realizes the electrical connection between the second contact portions 212 and one conductive member 220, the metal plate 3 can also be used as a structure for supporting the sample holder 11, so that the sample holder 11 can be stably disposed on the frame body 1.
Optionally, the conductive member 220 is a conductive column, and in an embodiment, one end of the conductive column is disposed on at least one metal plate 3, and the other end of the conductive column is far away from the metal plate 3 and can contact with the conductive brush 30. In addition, the conductive member 220 may be integrally formed with the metal plate 3, which facilitates the manufacturing process of the conductive member 220. It is understood that in another embodiment, the other end of the conductive post may also be disposed on the sample gear plate 50 to facilitate the conductive brush 30 contacting the conductive post. Of course, in other embodiments, the conductive member 220 may further include a conductive adhesive layer adhered on the second surface 32 of the metal plate 3, and when the conductive adhesive layer contacts the conductive brush 30, static electricity on the conductive adhesive layer is conducted to the conductive brush 30.
Optionally, one sample holder 11 and one metal spring 210 may be fixed to the metal plate 3 through the same hole on the metal plate 3 by the same screw, so as to avoid forming too many holes on the metal plate 3, and optimize the structure of the sample holder 10.
Alternatively, as shown in fig. 9, the sidewall 112 of the sample holder 11 may have at least one hollow portion 15, the number of the hollow portions 15 corresponds to the number of the first elastic contact portions 211, and one first elastic contact portion 211 extends into the sample holder 11 through one hollow portion 15. Specifically, after the second contact portion 212 is fixed to the metal plate 3 by screws, the two first elastic contact portions 211 connected to the second contact portion 212 extend into the sample holder 11 through one hollow portion 15.
When the sample loading mechanism 100 according to the embodiment of the present application is used, the sample container is first placed in the sample holder 11, and at this time, the first elastic contact portion 211 in the sample holder 11 can be tightly attached to the outer wall of the sample container, so that the first elastic contact portion 211 can sequentially transmit static electricity on the outer wall of the sample container to the conductive brush 30 and the ground through the second contact portion 212, thereby removing the static electricity on the sample container.
This application is used for elastic contact sample container through the first elastic contact portion 211 with metal shrapnel 210 in the subassembly 2 that destatics, and metal shrapnel 210's second elastic part can be connected with the electrically conductive brush 30 of ground connection, thereby make static on the sample container can be conducted to first elastic contact portion 211 in proper order, second contact portion 212 and electrically conductive brush 30, electrically conductive brush 30 and sample container direct contact are avoided in this metal shrapnel 210's setting, make the sample container homoenergetic of co-altitude all can contact with first elastic contact portion 211, thereby a sample frame 10 that can lead static on the sample container of co-altitude not is provided.
The embodiment of the application also provides a sample analyzer 1000, especially a chemiluminescence immunoassay analyzer, which is used for analyzing and detecting a sample to be detected so as to obtain a corresponding detection result and meet the use requirement. It should be noted that the specific type of sample to be tested is not limited, and in some embodiments, the sample to be tested includes a solid sample or a liquid sample. It can be understood that the liquid sample is detected by carrying the liquid sample through a container such as a test tube and placing the liquid sample on a sample rack. Further liquid samples include, but are not limited to, blood samples. The sample analyzer 1000 includes the sample loading mechanism described above.
Specifically, referring to fig. 10, the sample analyzer 1000 may include a sample reagent storage device 1001 for loading a sample and a reagent, a dispensing device 1003 for sucking and discharging the sample and the reagent, a mixing base (not shown) for supporting a reaction vessel, an incubation photometric device 1002 for incubation and luminescence detection, a magnetic separation cleaning device 1004 for separation cleaning, a reaction vessel gripping device 1005 for transferring the reaction vessel, and a liquid path device (not shown).
The sample reagent storing device 1004 includes the sample loading mechanism for loading a sample and a reagent loading mechanism for loading a reagent, the sample loading mechanism is sleeved outside the reagent loading mechanism, and the sample loading mechanism and the reagent loading mechanism rotate independently. The structure of the sample loading mechanism is shown in the embodiment corresponding to fig. 1 to 9, and is not repeated herein.
The reaction vessel gripping device 1005 transfers the reaction vessel to the blending seat; the dispensing device 1003 is located above the sample reagent storage device 1001, and can transfer a sample and a reagent to a reaction vessel of the mixing base; the reaction vessel grabbing device 1005 transfers the reaction vessel from the blending seat to the incubation photometric device 1002 for incubation, the reaction vessel grabbing device 1005 further transfers the incubated reaction vessel to the magnetic separation cleaning device 1004 for separation and cleaning, and transfers the separated and cleaned reaction vessel to the incubation photometric device 1002 for luminescence detection;
the liquid path device is connected to the dispensing device 1003 and the magnetic separation and cleaning device 1004, controls the dispensing device 1003 to aspirate and discharge a sample or a reagent and cleans the dispensing device 1003, and is also used to inject or discharge a cleaning liquid into or from the magnetic separation and cleaning device 1004.
The application provides a sample analyzer 1000 is used for elastic contact sample container through the first elastic contact portion of the metal shrapnel in the subassembly that destatics, and the second elastic part of metal shrapnel can be connected with the electrically conductive brush of ground connection, thereby makes and places static on the sample container in the sample seat can be conducted in proper order extremely first elastic contact portion the second contact portion with electrically conductive brush, the setting of this metal shrapnel avoids electrically conductive brush and sample container direct contact for the sample container homoenergetic of co-altitude all can contact with first elastic contact portion, thereby provides one kind and can lead the sample frame of static away on the sample container of co-altitude not.
The features mentioned above in the description, the claims and the drawings can be combined with one another in any desired manner, insofar as they are of significance within the scope of the application. The advantages and features described for the sample rack apply in a corresponding manner to the sample loading mechanism and to the sample analyzer.
The foregoing is a preferred embodiment of the present application, and it should be noted that those skilled in the art can make several improvements and modifications without departing from the principle of the present application, and these improvements and modifications are also considered as the protection scope of the present application.
Claims (16)
1. A sample holder is characterized by comprising a holder body and a static electricity removing assembly mounted on the holder body, wherein the holder body is provided with a sample seat for placing a sample container, the static electricity removing assembly is provided with a metal elastic sheet for conducting away static electricity of the sample container placed in the sample seat, the metal elastic sheet is provided with a first elastic contact part and a second contact part which are connected, the first elastic contact part is used for elastically contacting the outer wall of the sample container placed in the sample seat, and the second contact part is used for being electrically connected with a grounded conductive brush, so that the static electricity on the sample container placed in the sample seat can be sequentially conducted to the first elastic contact part, the second contact part and the conductive brush.
2. The sample holder according to claim 1, wherein the first resilient contact portion has at least one convex section that is convex toward a vertical central axis of the respective sample holder so as to contact an outer wall of a sample container placed in the sample holder.
3. The specimen rack according to claim 2, wherein the at least one convex segment is configured as a trapezoid or a circular arc.
4. The sample holder according to claim 2, wherein the at least one convex section is disposed proximate to the opening of the sample holder so that the at least one convex section can contact the outer walls of sample containers of different heights placed in the sample holder.
5. The sample holder according to claim 1, wherein the first resilient contact portion is disposed inside the sample holder and the second contact portion is located outside the sample holder.
6. The specimen holder according to claim 5, wherein the bottom of the specimen holder is provided with through holes, the number of the through holes corresponds to the number of the first elastic contact portions, and the first elastic contact portions extend into the specimen holder through the through holes.
7. The sample holder as claimed in claim 1, wherein the static discharge assembly further comprises at least one conductive member fixed to the holder body, and the second contact portion is electrically connected to the conductive brush via the at least one conductive member, so that static electricity on the sample holder can be sequentially conducted to the first elastic contact portion, the second contact portion, the at least one conductive member and the conductive brush.
8. The specimen holder according to claim 7, further comprising a metal plate, wherein the holder body and the static discharge assembly are fixedly disposed on the metal plate, wherein the second contact portion is fixed on the metal plate, a portion of the conductive member is disposed on the metal plate, and another portion of the conductive member is capable of contacting the conductive brush.
9. The sample holder according to claim 8, wherein the metal plate has a first surface, a second surface and a mounting hole penetrating through the metal plate, the holder body is fixed on the first surface, the second contact portion is fixed on the second surface, and the first elastic contact portion protrudes into the corresponding sample holder through the mounting hole.
10. The sample rack according to claim 9, wherein the side wall of the sample holder has at least one cutout, the number of cutouts corresponding to the number of first elastic contact portions, the first elastic contact portions extending into the sample holder through the cutouts.
11. The sample rack according to any one of claims 1 to 10, wherein the number of the sample holders is the same as the number of the metal spring pieces, and each sample holder is provided with one metal spring piece correspondingly.
12. The sample holder according to claim 11, wherein each of the metal springs has two first elastic contact portions, and the two first elastic contact portions of each of the metal springs are connected to two sides of the second elastic contact portion of the metal spring.
13. The sample rack of claim 12, each first elastic contact portion of each metal dome having at least one convex section, wherein the convex section of one first elastic contact portion and the convex section of the other first elastic contact portion are convex toward each other and have a minimum distance therebetween smaller than an outer diameter of the sample container so as to be able to grip the sample container.
14. A sample loading mechanism comprising a grounded base plate, a conductive brush and a sample holder as claimed in any one of claims 1 to 13, the sample holder being supported on the base plate and the conductive brush being secured to the base plate.
15. The sample loading mechanism of claim 14, wherein one end of the conductive brush is fixed to the base plate and the other end of the conductive brush is positioned between the sample holder and the base plate, the sample holder being rotatable relative to the base plate.
16. A sample analyser, comprising a sample loading mechanism according to claim 14 or 15 for loading a sample.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910343690.3A CN111855989B (en) | 2019-04-26 | 2019-04-26 | Sample rack, sample loading mechanism and sample analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910343690.3A CN111855989B (en) | 2019-04-26 | 2019-04-26 | Sample rack, sample loading mechanism and sample analyzer |
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| CN111855989A true CN111855989A (en) | 2020-10-30 |
| CN111855989B CN111855989B (en) | 2024-06-11 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112337526A (en) * | 2020-11-22 | 2021-02-09 | 刘广芝 | Reagent is with moving positioning system that carries of sample frame |
| CN113203786A (en) * | 2021-06-11 | 2021-08-03 | 南昌大学 | Capillary electrophoresis apparatus |
| CN113325186A (en) * | 2021-04-22 | 2021-08-31 | 山东艾科达生物科技有限公司 | Full-automatic chemiluminescence immunoassay analyzer |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08285661A (en) * | 1995-04-12 | 1996-11-01 | Hitachi Ltd | Liquid level detecting device |
| JP2007309742A (en) * | 2006-05-17 | 2007-11-29 | Olympus Corp | Autoanalyzer |
| JP2008102032A (en) * | 2006-10-19 | 2008-05-01 | Olympus Corp | Rack conveyance mechanism and automatic analyzer |
| JP2018044797A (en) * | 2016-09-12 | 2018-03-22 | キヤノンメディカルシステムズ株式会社 | Automatic analyzer and specimen rack |
| CN208172026U (en) * | 2018-03-26 | 2018-11-30 | 成都深迈瑞医疗电子技术研究院有限公司 | Chemiluminescent analyzer and sample reagent load scanning system |
-
2019
- 2019-04-26 CN CN201910343690.3A patent/CN111855989B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08285661A (en) * | 1995-04-12 | 1996-11-01 | Hitachi Ltd | Liquid level detecting device |
| JP2007309742A (en) * | 2006-05-17 | 2007-11-29 | Olympus Corp | Autoanalyzer |
| JP2008102032A (en) * | 2006-10-19 | 2008-05-01 | Olympus Corp | Rack conveyance mechanism and automatic analyzer |
| JP2018044797A (en) * | 2016-09-12 | 2018-03-22 | キヤノンメディカルシステムズ株式会社 | Automatic analyzer and specimen rack |
| CN208172026U (en) * | 2018-03-26 | 2018-11-30 | 成都深迈瑞医疗电子技术研究院有限公司 | Chemiluminescent analyzer and sample reagent load scanning system |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112337526A (en) * | 2020-11-22 | 2021-02-09 | 刘广芝 | Reagent is with moving positioning system that carries of sample frame |
| CN113325186A (en) * | 2021-04-22 | 2021-08-31 | 山东艾科达生物科技有限公司 | Full-automatic chemiluminescence immunoassay analyzer |
| CN113203786A (en) * | 2021-06-11 | 2021-08-03 | 南昌大学 | Capillary electrophoresis apparatus |
| CN113203786B (en) * | 2021-06-11 | 2023-03-31 | 南昌大学 | Capillary electrophoresis apparatus |
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|---|---|
| CN111855989B (en) | 2024-06-11 |
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