CN111801575B - 区分细菌感染和病毒感染的多重横向流测定物 - Google Patents

区分细菌感染和病毒感染的多重横向流测定物 Download PDF

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Publication number
CN111801575B
CN111801575B CN201980015174.6A CN201980015174A CN111801575B CN 111801575 B CN111801575 B CN 111801575B CN 201980015174 A CN201980015174 A CN 201980015174A CN 111801575 B CN111801575 B CN 111801575B
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target analyte
concentration
analyte
complex
sample
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CN111801575A (zh
Inventor
任汇淼
杨健
G·刘
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Becton Dickinson and Co
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Becton Dickinson and Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G01N2333/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4 or KC
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153 or CD154

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201980015174.6A 2018-01-27 2019-01-24 区分细菌感染和病毒感染的多重横向流测定物 Active CN111801575B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311832413.1A CN117783514A (zh) 2018-01-27 2019-01-24 区分细菌感染和病毒感染的多重横向流测定物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862622877P 2018-01-27 2018-01-27
US62/622,877 2018-01-27
PCT/US2019/015005 WO2019147850A1 (en) 2018-01-27 2019-01-24 Multiplex lateral flow assay for differentiating bacterial infections from viral infections

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202311832413.1A Division CN117783514A (zh) 2018-01-27 2019-01-24 区分细菌感染和病毒感染的多重横向流测定物

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CN111801575A CN111801575A (zh) 2020-10-20
CN111801575B true CN111801575B (zh) 2024-01-12

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CN201980015174.6A Active CN111801575B (zh) 2018-01-27 2019-01-24 区分细菌感染和病毒感染的多重横向流测定物

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US (1) US20200348296A1 (enExample)
EP (1) EP3743719A4 (enExample)
JP (2) JP2021511524A (enExample)
CN (2) CN117783514A (enExample)
AU (1) AU2019212375B2 (enExample)
CA (1) CA3088124A1 (enExample)
WO (1) WO2019147850A1 (enExample)

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AU2021205508A1 (en) * 2020-01-10 2022-07-28 Ortho-Clinical Diagnostics, Inc. Substrate with channels for controlled fluid flow in biological assay sampling
US20230204574A1 (en) * 2020-04-24 2023-06-29 Massachusetts Institute Of Technology Rapid, point of care detection of neutralizing antibodies against a virus
EP4467959A1 (en) * 2023-05-26 2024-11-27 Leica Microsystems CMS GmbH Sample holder for a biological sample and method for analysing the biological sample

Citations (2)

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WO2014070686A1 (en) * 2012-10-29 2014-05-08 Sri International Lateral flow assay utilizing infrared dye for multiplex detection
CN105723220A (zh) * 2013-11-12 2016-06-29 光州科学技术院 能够测定广泛浓度范围的生物物质浓度的免疫层析条状传感器

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US7239394B2 (en) * 2003-06-04 2007-07-03 Inverness Medical Switzerland Gmbh Early determination of assay results
WO2005095967A1 (en) * 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
US7439079B2 (en) * 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US20070224701A1 (en) * 2006-02-16 2007-09-27 Becton, Dickinson And Company Combination vertical and lateral flow immunoassay device
US20130196310A1 (en) * 2008-05-20 2013-08-01 Rapid Pathogen Screening, Inc. Method and Device for Combined Detection of Viral and Bacterial Infections
JP5798720B2 (ja) * 2010-03-30 2015-10-21 積水メディカル株式会社 ヒトｃ反応性タンパク質（ｃｒｐ）測定用イムノクロマト試薬
US9506913B2 (en) * 2010-07-15 2016-11-29 University Of Pretoria Method of detecting surrogate markers in a serum sample
BR112014010718B1 (pt) * 2011-11-16 2020-12-22 Becton, Dickinson And Company métodos, sistemas, dispositivos e kits para detecção de analito em amostra
AU2012367247B2 (en) * 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
CN108802385B (zh) * 2012-02-09 2022-02-08 米密德诊断学有限公司 用于诊断感染的标记和决定因素和其使用方法
EP2923204A1 (en) * 2012-10-31 2015-09-30 Astute Medical, Inc. Quantitative lateral flow assay
CN104937418B (zh) * 2012-11-15 2019-08-23 奥索临床诊断有限公司 使用反应时间的校准分析
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EP3475702B3 (en) * 2016-06-23 2024-03-20 Memed Diagnostics Ltd. Measuring trail by lateral flow immunoassay
ES2938645T3 (es) * 2017-06-28 2023-04-13 Becton Dickinson Co Ensayos de tipo sándwich que utilizan partes de señal decreciente de la curva de respuesta de dosis para medir analitos, incluyendo analitos a concentración elevada

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WO2014070686A1 (en) * 2012-10-29 2014-05-08 Sri International Lateral flow assay utilizing infrared dye for multiplex detection
CN105723220A (zh) * 2013-11-12 2016-06-29 光州科学技术院 能够测定广泛浓度范围的生物物质浓度的免疫层析条状传感器

Also Published As

Publication number Publication date
EP3743719A1 (en) 2020-12-02
CN111801575A (zh) 2020-10-20
JP2021511524A (ja) 2021-05-06
US20200348296A1 (en) 2020-11-05
AU2019212375B2 (en) 2025-06-26
AU2019212375A1 (en) 2020-07-30
WO2019147850A1 (en) 2019-08-01
CA3088124A1 (en) 2019-08-01
EP3743719A4 (en) 2021-11-03
JP2024057619A (ja) 2024-04-24
CN117783514A (zh) 2024-03-29

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