CN111792119A - Online sterilization method and device for filling pipeline - Google Patents
Online sterilization method and device for filling pipeline Download PDFInfo
- Publication number
- CN111792119A CN111792119A CN202010746496.2A CN202010746496A CN111792119A CN 111792119 A CN111792119 A CN 111792119A CN 202010746496 A CN202010746496 A CN 202010746496A CN 111792119 A CN111792119 A CN 111792119A
- Authority
- CN
- China
- Prior art keywords
- cavity
- pressure
- filling
- pipeline
- sterilization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000001954 sterilising effect Effects 0.000 title claims abstract description 158
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 128
- 238000000034 method Methods 0.000 title claims abstract description 42
- 238000007789 sealing Methods 0.000 claims abstract description 105
- 239000007788 liquid Substances 0.000 claims description 110
- 239000012530 fluid Substances 0.000 claims description 26
- 238000004140 cleaning Methods 0.000 abstract description 42
- 230000008569 process Effects 0.000 description 20
- 230000002262 irrigation Effects 0.000 description 14
- 238000003973 irrigation Methods 0.000 description 14
- 230000006872 improvement Effects 0.000 description 12
- 238000004519 manufacturing process Methods 0.000 description 11
- 230000002572 peristaltic effect Effects 0.000 description 11
- 238000010586 diagram Methods 0.000 description 8
- 230000000712 assembly Effects 0.000 description 6
- 238000000429 assembly Methods 0.000 description 6
- 230000008859 change Effects 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 238000004321 preservation Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 230000005489 elastic deformation Effects 0.000 description 2
- 239000003779 heat-resistant material Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000003206 sterilizing agent Substances 0.000 description 2
- 230000004308 accommodation Effects 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
- B65B55/12—Sterilising contents prior to, or during, packaging
- B65B55/14—Sterilising contents prior to, or during, packaging by heat
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B2210/00—Specific aspects of the packaging machine
- B65B2210/06—Sterilising or cleaning machinery or conduits
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention discloses an online sterilization method of a filling pipeline.A pressure-resistant closed cavity is arranged on the filling pipeline, and the pipeline, a filling needle and a joint are integrally placed into the pressure-resistant closed cavity when online sterilization is carried out; and introducing an autoclave medium into the pressure-resistant closed cavity, and performing online sterilization operation on the pipeline, the filling needle and the joint by using the autoclave medium. According to the invention, the pressure-resistant closed chamber is arranged on the pipeline of the filling system, so that the pipeline assembly can be integrally placed into the pressure-resistant closed chamber for online sterilization, and the method has the advantages of simplicity in operation, safety, reliability, high sterilization efficiency and the like. The invention discloses an online sterilization device for implementing the online sterilization method of the filling pipeline, and the device has the advantages of good sealing performance, safety, reliability, capability of cleaning and sterilizing a plurality of groups of pipeline components at the same time and the like.
Description
Technical Field
The invention mainly relates to the technical field of filling, in particular to an online sterilization method and device for a filling pipeline.
Background
The conventional peristaltic pump filling system generally comprises a liquid dispenser, a peristaltic pipeline, a peristaltic pump and a filling needle. The front end of the liquid distributor is connected with the liquid distribution system through a hard pipe, and the pipeline systems before the liquid distributor are all hard pipes and can resist high temperature and high pressure, so that the pipeline at the front end of the liquid distributor can be easily sterilized on line. And the rear end of the liquid distributor is connected with a hose which passes through the peristaltic pump to be connected with the filling, and the hose is connected in a hose inserting mode, so that the hose and the hose inserting mode cannot bear high temperature and high pressure, and online sterilization cannot be realized. At present, peristaltic pumps are widely applied in the field of medicines, hoses of peristaltic pumps often need to be cleaned and sterilized in a medicine production environment with high production requirements, the hoses are usually required to be detached from a pump body for cleaning, sterilizing and other operations, and the hoses are installed back to the peristaltic pumps after sterilization is finished. In the prior art, if online sterilization is to be realized for a peristaltic pump filling system, a joint is reinforced in sections, and the pressure resistance of a pipeline is increased in a mode that a hose is wrapped by hard objects in sections, so that online sterilization is realized. The pipeline needs to be wrapped and fixed in a segmented mode, the joint needs to be customized and reinforced, and the operation is troublesome, time-consuming and labor-consuming, so that the pipeline is difficult to accept by enterprises.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a simple, safe and reliable online sterilization method and device for a filling pipeline of a peristaltic pump.
In order to solve the technical problems, the invention adopts the following technical scheme:
an online sterilization method for filling pipelines comprises the steps that a pressure-resistant closed cavity is arranged on a filling pipeline, and when online sterilization is carried out, the pipeline, a filling needle and a joint are integrally placed into the pressure-resistant closed cavity; and introducing an autoclave medium into the pressure-resistant closed cavity, and performing online sterilization operation on the pipeline, the filling needle and the joint by using the autoclave medium.
As a further improvement of the invention, the front end of a liquid distributor of a filling pipeline is connected by a hard pipe, and the rear end of the liquid distributor is provided with a pressure-resistant closed chamber which can be opened together with the liquid distributor; the hose connector of the liquid distributor is arranged in the pressure-resistant sealed cavity, and the space in the pressure-resistant sealed cavity is used for placing a pipeline at the rear end of the liquid distributor and filling needles.
As a further improvement of the invention, a door is arranged on the pressure-resistant closed chamber, after the door is closed, the pressure-resistant closed chamber is closed, and after the door is opened, the hose is taken out.
As a further improvement of the invention, the pressure-resistant closed chamber is provided with a quick clamping joint hole for installing a drain valve and a pressure gauge at the sterilization tail end, or the quick clamping joint hole is directly connected with other sterilization pipelines for online sterilization.
As a general inventive concept, the present invention also provides an on-line sterilization apparatus for a filling line, the on-line sterilization apparatus including a pressure-tight chamber, the pressure-tight chamber including: the device comprises a cavity, a cover body and a liquid distributor; the top end and the bottom end of the cavity are communicated, and the top end of the cavity is detachably and hermetically connected with the cover body through a fastener; the bottom end of the cavity is provided with a boss extending outwards, and the boss is detachably connected with the liquid distributor in a sealing manner through a fastener; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
As a general inventive concept, the present invention also provides an on-line sterilization apparatus for a filling line, the on-line sterilization apparatus including a pressure-tight chamber, the pressure-tight chamber including: a cavity and a liquid distributor; the top end of the cavity is provided with a through boss extending outwards, and the bottom end of the cavity is provided with a sealing structure; the boss is detachably connected with the liquid distributor in a sealing manner through a fastener; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
As a general inventive concept, the present invention also provides an on-line sterilization apparatus for a filling line, the on-line sterilization apparatus including a pressure-tight chamber, the pressure-tight chamber including: the liquid distributor comprises a cavity and a liquid distributor, wherein a through boss extending outwards is arranged at the top end of the cavity, a sealing structure is arranged at the bottom end of the cavity, a cover door is arranged on the side part of the cavity, and the cavity and the cover door are in detachable sealing connection through a fastener; the boss is fixedly connected with the liquid distributor in a sealing manner; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
As a further improvement of the invention, the liquid separator is provided with at least one pipeline connector, and the liquid separator is also provided with at least one fluid inlet; the pipeline interface and the fluid inlet are respectively positioned on different sides of the liquid separator; when online sterilization is carried out, the pipeline interface extends into the cavity.
As a further improvement of the invention, a hose fixing frame and an irrigation needle fixing frame are respectively arranged on two inner side walls of the cavity; the hose fixing frame is provided with at least one hose fixing groove, and the filling needle fixing frame is provided with at least one filling needle fixing hole.
As a further improvement of the invention, the hose fixing groove and the irrigation needle fixing hole are positioned on the same horizontal plane.
As a further improvement of the invention, a hose fixing frame and a filling needle sealing box are respectively arranged on two inner side walls of the cavity; the hose fixing frame is provided with at least one hose fixing groove, and the top of the filling needle sealing box is provided with at least one filling needle fixing hole; the filling needle of the pipeline assembly is sealed in the filling needle sealing box through the filling needle fixing hole; and an inflation connector is arranged on the outer side wall of the cavity.
As a further improvement of the invention, the hose fixing groove and the irrigation needle fixing hole are positioned on the same horizontal plane.
As a further improvement of the invention, the cover door is rotatably arranged at the side part of the cavity through a hinge; a filling needle sealing box is arranged on the inner side wall of the cavity; the top of the filling needle sealing box is provided with at least one filling needle fixing hole, and a filling needle of the pipeline assembly is sealed in the filling needle sealing box through the filling needle fixing hole; the side wall of the needle filling sealing box is provided with an exhaust interface, and the exhaust interface penetrates through the side wall of the cavity and is connected to the outside of the pressure-resistant closed chamber; and an inflation connector is arranged on the outer side wall of the cavity.
As a further improvement of the invention, a groove is formed in the edge of the port of the cover body, and a sealing element is arranged in the groove; the wall thickness of the port of the cavity is matched with the size of the groove; the cavity and the cover body form a pressure-resistant closed cavity with a one-piece structure through a hinge.
As a further improvement of the invention, the fastener is a spring clip, a bolt, a latch or a screw.
As a further improvement of the present invention, the fastener includes a fastening band and a bolt.
Compared with the prior art, the invention has the advantages that:
1. according to the online sterilization method for the filling pipeline, the pressure-resistant closed cavity is arranged on the pipeline, so that the pipeline assembly can be integrally placed into the pressure-resistant closed cavity for online sterilization, and the online sterilization method has the advantages of simplicity in operation, safety, reliability, high sterilization efficiency and the like.
2. According to the online sterilization device for the filling pipeline, the cover body and the liquid distributor are respectively connected at the two ends of the through cavity in a sealing manner, so that the pressure-resistant closed cavity which is simple in structure, good in sealing performance, safe, reliable, large in accommodating space and capable of cleaning and sterilizing multiple groups of pipeline assemblies simultaneously is formed. When the filling system works, all pipeline components of the filling system are taken down and placed in the pressure-resistant closed cavity, high-pressure sterilization medium (such as high-temperature steam) is input through the pipeline components, and the high-pressure sterilization medium flows into the pressure-resistant closed cavity along the pipeline, so that the inside of the hose and the inside of the pressure-resistant closed cavity are both in a high-temperature high-pressure state, the internal and external pressures of the wall of the hose in the pressure-resistant closed cavity are consistent or close to each other, the hose is effectively prevented from expanding and breaking, and online cleaning and sterilization of the filled.
3. According to the online sterilization device for the filling pipeline, one end of the cavity is arranged to be a sealing structure, and the other end of the cavity is hermetically connected with the liquid distributor, so that the structure of the pressure-resistant closed cavity is simplified, and the online sterilization device for the filling pipeline still has the advantages of good sealing performance, safety, reliability, capability of cleaning and sterilizing multiple groups of pipeline assemblies and the like.
4. According to the online sterilization device for the filling pipeline, the liquid distributor is fixedly connected with the cavity in a sealing manner, the liquid distributor and the cavity do not need to be moved respectively in the working process, the overall sealing performance of the pressure-resistant closed cavity is improved, and meanwhile, the cover door is arranged on the side part of the cavity, so that a pipeline assembly can conveniently enter and exit the pressure-resistant closed cavity from the cover door; in the process of filling, the pipeline assembly extends out of the cavity from the cover door, corresponding metering and conveying work is carried out, when cleaning and sterilizing are needed, the pipeline assembly is stored into the pressure-resistant airtight chamber from the cover door, the cover door and the cavity are sealed, the pipeline assembly can be cleaned and sterilized on line, and the pipeline assembly has the advantages of good sealing performance, simplicity and convenience in operation, safety, reliability and the like.
5. According to the online sterilization device for the filling pipeline, the cavity is hermetically connected with the liquid distributor, the liquid distributor is provided with the plurality of pipeline interfaces, the starting end of the pipeline assembly is pulled out of the cavity, and when cleaning and sterilization are needed, the pipeline assembly only needs to be retracted into the pressure-resistant sealed cavity, so that the online sterilization device is simple and rapid, and the working efficiency is effectively improved.
6. According to the online sterilization device for the filling pipeline, the hose fixing frame, the filling needle fixing frame or the filling needle sealing box are arranged on the two inner side walls of the cavity in parallel and oppositely, and the plurality of hose fixing grooves and the plurality of filling needle fixing holes are correspondingly arranged, so that the phenomenon that a plurality of pipeline assemblies are wound in a pressure-resistant sealed cavity to cause sterilization dead angles and incomplete cleaning and sterilization is avoided, the ordered arrangement of the plurality of pipeline assemblies in the pressure-resistant sealed cavity is realized, the cleaning and sterilization effects of the pipeline assemblies are improved, and the production requirements for cleaning and sterilizing large batches of pipeline assemblies at the same time are well met.
Drawings
Fig. 1 is a schematic perspective view of a pressure-tight chamber according to embodiment 1 of the present invention.
Fig. 2 is a schematic structural principle diagram of the pipeline assembly placed in a pressure-tight chamber for sterilization in embodiment 1 of the present invention.
Fig. 3 is a schematic structural principle diagram of the pipeline assembly placed in a pressure-tight chamber for sterilization in embodiment 2 of the present invention.
Fig. 4 is a schematic structural diagram of a pressure-tight chamber and filling equipment combination in embodiments 1 and 2 of the present invention.
Fig. 5 is a schematic structural diagram of another view of the pressure-tight chamber and filling equipment combination in embodiments 1 and 2 of the present invention.
Fig. 6 is a schematic structural principle view of the pipeline assembly placed in a pressure-tight chamber for sterilization in embodiment 3 of the present invention.
Fig. 7 is a schematic structural diagram of a pressure-tight chamber in embodiment 3 of the present invention.
Fig. 8 is a schematic structural diagram of the pipeline assembly placed in a pressure-tight chamber for sterilization in embodiment 4 of the present invention.
Fig. 9 is a schematic structural diagram of the pipeline assembly placed in a pressure-tight chamber for sterilization in embodiment 5 of the present invention.
Fig. 10 is a schematic structural diagram of a pressure-tight chamber in embodiment 5 of the present invention.
Illustration of the drawings:
1. a cavity; 2. a cover body; 3. buckling; 4. a liquid separator; 41. a pipeline interface; 42. a fluid inlet; 5, fixing a hose; 51. a hose fixing groove; 6. a perfusion needle fixing frame; 61. filling needle fixing holes; 7. filling a needle sealing box; 8, filling equipment; 9. a seal ring; 10. a boss; 11. an output end hose; 12. a hose connector; 13. an elastic hose; 14. an input end hose; 15. filling a needle; 16. a hinge; 17. fixing the rod; 18. a fastening tape; 19. a bolt; 20. a support plate; 21 an inflation interface; 22. covering the door; 23. locking; 24. an exhaust interface.
Detailed Description
The invention is further described below with reference to the drawings and specific preferred embodiments of the description, without thereby limiting the scope of protection of the invention.
The invention relates to an online sterilization method of a filling pipeline.A pressure-resistant closed cavity is arranged on the filling pipeline, and when online sterilization is carried out, the pipeline, a filling needle and a joint are integrally placed into the pressure-resistant closed cavity; and introducing an autoclave medium into the pressure-resistant closed cavity, and performing online sterilization operation on the pipeline, the filling needle and the joint by using the autoclave medium. The pressure-resistant closed chamber is arranged on the pipeline of the filling system (such as filling by a peristaltic pump), so that the pipeline assembly can be integrally placed into the pressure-resistant closed chamber for online sterilization, and the method has the advantages of simplicity in operation, safety, reliability, high sterilization efficiency and the like.
Furthermore, the front end of a liquid distributor of the filling pipeline is connected by a hard pipe, and the rear end of the liquid distributor and the liquid distributor are provided with a pressure-resistant closed chamber which can be opened; the hose connector of the liquid separator is arranged in the pressure-resistant sealed cavity, and the space in the pressure-resistant sealed cavity is used for placing a pipeline at the rear end of the liquid separator and a filling needle. The hose connector of the liquid distributor is placed in the pressure-resistant sealed cavity, the liquid distributor also becomes a part of the pressure-resistant sealed cavity, and the pipeline assembly connected with the hose connector can be integrally placed in the pressure-resistant sealed cavity for online sterilization, so that the high-efficiency sterilization of the whole pipeline assembly is realized. In the specific application process, in order to improve the flexibility of the sterilization operation, a door can be arranged on the pressure-resistant closed chamber, and the pressure-resistant closed chamber is closed after the door is closed; after opening the door, the hose can be taken out.
Furthermore, the pressure-resistant closed chamber is provided with a quick clamping joint hole for installing a drain valve and a pressure gauge at the end of sterilization, or the quick clamping joint hole is directly connected with other sterilization pipelines for online sterilization. Through being provided with fast joint hole at withstand voltage airtight cavity, both can realize that other sterilization auxiliary device are fixed in the installation of withstand voltage airtight cavity, can carry out the sequencing management with the pipeline subassembly in withstand voltage airtight strong room again, improve withstand voltage airtight cavity's utilization ratio.
Example 1
As shown in fig. 1 and fig. 2, fig. 4 and fig. 5, the online sterilization apparatus for a filling line of the present invention is used for implementing the online sterilization method for a filling line, and includes a pressure-tight chamber, and further, the pressure-tight chamber includes: the device comprises a cavity 1, a cover body 2 and a liquid distributor 4; the top end and the bottom end of the cavity 1 are communicated, and the top end of the cavity 1 is detachably and hermetically connected with the cover body 2 through a fastener; the bottom end of the cavity 1 is provided with a boss 10 extending outwards, and the boss 10 is detachably and hermetically connected with the liquid distributor 4 through a fastener; when online sterilization is carried out, a pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium (such as high-temperature steam) is input into the pressure-resistant sealed cavity through the pipeline assembly.
In this embodiment, a sealing member is disposed at the covering connection position of the cavity 1 and the cover body 2; the cavity 1 and the cover 2 form a pressure-resistant airtight chamber with a one-piece structure through a hinge 16. Further, the fastener for detachably connecting the cavity 1 and the cover 2 may specifically be a spring buckle 3, or may be a bolt, a latch, or a screw. It can be understood that all fastening structures capable of ensuring the effective fixed covering of the cavity 1 and the cover 2 and the flexible disassembly are within the protection scope of the present invention.
In this embodiment, through sealing connection lid and knockout respectively at cavity both ends that link up, constitute simple structure, the leakproofness is good, safe and reliable and accommodation space is big, can wash the airtight cavity of withstand voltage of sterilization to the multiunit pipeline subassembly simultaneously. When the filling system works, all pipeline components of the filling system are taken down and placed in the pressure-resistant closed chamber, high-pressure sterilization medium is input through the pipeline components and flows into the pressure-resistant closed chamber along the pipeline, so that the inside of the hose and the inside of the pressure-resistant closed chamber are both in a high-temperature high-pressure state, the internal and external pressures of the wall of the hose in the pressure-resistant closed chamber are consistent or close to each other, the hose is effectively prevented from expanding and breaking, and online cleaning and sterilization of the filled hose are realized.
In this embodiment, the liquid separator 4 is provided with at least one pipe connector 41, and the liquid separator 4 is further provided with a fluid inlet 42; the pipe connection 41 and the fluid inlet 42 are respectively located on different sides of the liquid separator 4; when performing on-line sterilization, the pipeline interface 41 extends into the cavity 1.
Specifically, the liquid separator 4 is a cylindrical structure with two sealed ends, two sides along the length direction of the cylinder are parallel to each other and are oppositely provided with a pipeline connector 41 and a fluid inlet 42, and the pipeline connector 41 and the fluid inlet 42 are respectively arranged on two opposite sides of the liquid separator 4. One side of the liquid distributor 4 with the pipeline interface 41 is hermetically connected with the boss 10, the pipeline interface 41 extends into the cavity 1, the fluid inlet 42 arranged at the opposite side of the pipeline interface 41 is exposed outside the pressure-resistant closed chamber, and fluid to be metered and conveyed enters the liquid distributor 4 through the fluid inlet 42 and finally enters the filling system. It can be understood that, in order to improve the sealing performance between the liquid distributor 4 and the boss 10, the two ends of the boss 10 may be provided with a curved structure having a curvature, which is the same as the curvature of the liquid distributor 4 and is attached to the liquid distributor 4. Further, a sealing member is arranged between the boss 10 and the liquid distributor 4. Specifically, the sealing between the boss 10 and the liquid distributor 4 can be realized by using a sealing strip, or the sealing between the boss 10 and the liquid distributor 4 can be realized by manufacturing a contact sleeve on the surface of the liquid distributor 4 with sealing performance. It is understood that all configurations that ensure an effective seal between the boss 10 and the liquid distributor 4 are within the scope of the present invention.
In this embodiment, the fastening member for connecting the boss 10 and the liquid distributor 19 may be a spring clip 3, or may be a bolt, a latch or a screw. It is understood that all fastening structures that ensure an effective and secure connection of the projection 10 to the liquid distributor 4 and that allow flexible disassembly are within the scope of the present invention.
In this embodiment, set up cavity and lid into the withstand voltage airtight cavity of disjunctor formula of dismantling sealing connection through the hinge, set up the knockout simultaneously in the cavity bottom, in the pipeline interface end of knockout upwards stretched into the cavity to a plurality of pipeline interfaces have been set up on the knockout, the initiating terminal of pipeline subassembly was drawn out in the withstand voltage airtight cavity promptly, when needing to wash the sterilization, only need with the pipeline subassembly retrieve in withstand voltage airtight cavity can, simple swift has effectively improved work efficiency.
As shown in fig. 1, in the present embodiment, a hose fixing frame 5 and an irrigation needle fixing frame 6 are respectively disposed on the upper portions of two inner side walls along the length direction of the cavity 1. Further, at least one hose fixing groove 51 is formed in the hose fixing frame 5, and at least one irrigation needle fixing hole 61 is formed in the irrigation needle fixing frame 6. Both satisfied the production demand of carrying out the cleaning and sterilizing to many pipeline subassemblies simultaneously, avoided the pipeline subassembly again to twine each other in withstand voltage airtight chamber and exist the sterilization dead angle, lead to cleaning and sterilizing not thorough, realized many pipeline subassemblies at withstand voltage airtight chamber in-order arrangement, improved the effect of pipeline subassembly cleaning and sterilizing.
It should be noted that, in this embodiment, the hose fixing frame 5 and the irrigation needle fixing frame 6 are parallel and opposite to each other, that is, the hose fixing frame 5 and the irrigation needle fixing frame 6 are respectively fixed on two opposite sides of the upper portion of the inner side of the cavity 1. The hose fixing groove 51 and the irrigation needle fixing hole 61 may be at the same level. The hose fixing frame 5, the filling needle fixing frame 6 and the liquid distributor 4 are parallel to each other in the axial direction, and in the process of cleaning and sterilizing, the pipeline components are orderly arranged and fixed in the pressure-resistant sealed cavity through the cooperation of the hose fixing frame, the filling needle fixing frame 6 and the liquid distributor 4. It is understood that the specific locations of the hose holder 5 and the irrigation needle holder 6 in the cavity 1 are not particularly limited, as long as the fixation of the pipeline assembly can be achieved.
As shown in fig. 2, in the embodiment, a groove is formed at the top edge of the cover body 2, and a sealing member is disposed in the groove. The top wall thickness of the cavity 1 is matched with the size of the groove. When lid 2 and cavity 1 lid were fashionable, in the recess on 2 tops of cavity 1's top edge embedding lid, compressed tightly the sealing member in the recess, effectively promoted the whole sealing performance of withstand voltage airtight cavity, better satisfied the required high temperature high pressure seal environment of hose assembly washing sterilization. In particular, the sealing element provided in the recess of the lid 2 may take the form of a sealing ring 9. It is understood that all structures that can ensure the effective sealing between the chamber 1 and the cover 2 are within the scope of the present invention.
In this embodiment, as shown in fig. 4 and 5, the pressure-tight chamber is connected to a filling device 8 (e.g., a peristaltic pump filling device) by a fixing rod 17. Further, the fixing rods 17 are arranged on the left side and the right side of the cavity 1, so that the pressure-resistant closed chamber is fixedly connected with the filling equipment 8. In this embodiment, utilize dead lever 17 to install withstand voltage airtight cavity on filling equipment 8, have advantages such as the dismouting is nimble, reliable and stable, simultaneously also can be fine satisfy the filling hose assembly and carry out the demand of online washing sterilization. It can be understood that in the practical application process, the pressure-resistant closed chamber can be directly fixed on the filling equipment or not fixed on the filling equipment; the specific installation position of the pressure-resistant closed chamber on the filling equipment can also be determined according to the actual production operation environment, and the requirement of online cleaning and sterilization of the pipeline assembly is met.
During operation, the pressure-resistant airtight chamber is installed on the filling equipment 8 through the fixing rod 17 and is close to one side of the pipeline assembly, the boss 10 at the bottom of the cavity 1 is detachably and hermetically connected with the liquid distributor 4 through the spring buckle 3, the pipeline interface 41 of the liquid distributor 4 extends into the cavity 1, and the fluid inlet 42 of the liquid distributor 4 is exposed outside the pressure-resistant airtight chamber. The input end hose 14 of the pipeline assembly is connected with the pipeline interface 41 of the liquid separator 4, the input end hose 14 is fixedly guided through the hose fixing groove 51 on the hose fixing frame 5, and other components of the pipeline assembly are led out from the top end of the cavity 1 and fixed on the filling equipment 8. When the fluid metering and conveying are completed and the pipeline assembly needs to be cleaned and sterilized on line, the hose joint 12 is detached from the filling equipment 8, and the pipeline assembly consisting of the input end hose 14, the elastic hose 13, the output end hose 11 and the filling needle 15 can be integrally transferred into a pressure-resistant closed chamber. Wherein, the irrigation needle 15 of the pipeline component is fixed in the irrigation needle fixing hole 61 on the irrigation needle fixing frame 6. The hose fixing frame 5 and the filling needle fixing frame 6 are utilized to realize the ordered arrangement of the plurality of pipeline components in the pressure-resistant sealed cavity, and the plurality of pipelines are prevented from being intertwined. Cover body 2 and cavity 1 lid and close, fasten the sealed back through spring buckle 3 to cavity 1 and cover body 2, can be through the fluid entry 42 on the knockout 4 to input end hose 14 delivery steam, and then carry out the washing sterilization of pipeline subassembly in the withstand voltage closed chamber with high-temperature steam input. Meanwhile, the steam input quantity entering the pressure-resistant sealed cavity is monitored in real time at the steam input end, and the steam input quantity is adjusted in time, so that the cleaning and sterilizing effects of the pipeline assembly are ensured, and the consumption of the steam is reduced.
It can be understood that, in order to improve the heat preservation and pressure maintaining performance of the pressure-proof closed cavity, the inner walls of the cavity 1 and the cover body 2 of the pressure-proof closed cavity can be made of heat preservation materials with high temperature and high pressure resistance. Meanwhile, in order to improve the safety of the pressure-resistant sealed chamber, the outer walls of the chamber body 1 and the cover body 2 may be made of heat-resistant materials.
Example 2
As shown in fig. 3 to 5, the online sterilization apparatus for a filling line according to the present invention is used for implementing the online sterilization method for a filling line, and has a structure and an operation principle substantially the same as those of the online sterilization apparatus in embodiment 1, and the difference is that: the upper parts of two inner side walls along the length direction of the cavity 1 are respectively provided with a hose fixing frame 5 and a filling needle sealing box 7; the hose fixing frame 5 is provided with at least one hose fixing groove 51, and the top of the filling needle sealing box 7 is provided with at least one filling needle fixing hole 61. The filling needle sealing box 7 is fixed in the cavity 1 through a supporting plate 20; the filling needle 15 of the pipeline component is sealed in the filling needle sealing box 7 through the filling needle fixing hole 61; an air inflation interface 21 is arranged on the outer side wall of the cavity 1.
It should be noted that, in this embodiment, the hose fixing frame 5 and the filling needle sealing box 7 are parallel and opposite to each other, that is, the hose fixing frame 5 and the filling needle sealing box 7 are respectively fixed on two opposite sides of the upper portion inside the cavity 1. The hose fixing groove 51 and the irrigation needle fixing hole 61 may be at the same level. The hose fixing frame 5, the filling needle sealing box 7 and the liquid distributor 4 are parallel to each other in the axial direction, and in the process of cleaning and sterilizing, the pipeline components are orderly arranged and fixed in the pressure-resistant sealed cavity through the cooperation of the hose fixing frame, the filling needle sealing box 7 and the liquid distributor 4. It will be understood that the specific locations of the hose fixing frame 5 and the filling needle sealing box 7 in the cavity 1 are not particularly limited, as long as the fixing of the pipeline assembly can be achieved. The position of the air charging connector 21 is not particularly limited, as long as the air charging connector 21 can charge air into the pressure-resistant sealed cavity to ensure that the internal pressure and the external pressure of the hose are the same in the cleaning and sterilizing process.
When the pipeline assembly works, the filling needle 15 of the pipeline assembly is sealed in the filling needle sealing box 7, and the outer wall of the joint of the filling needle 15 has certain elasticity, so that the sealing connection between the filling needle 15 and the filling needle sealing box 7 can be realized by utilizing the limiting effect of the filling needle fixing hole 61. Steam is supplied to the inlet hose 14 through the fluid inlet 42 of the dispenser 4, and the high temperature steam is supplied to the pipe assembly for cleaning and sterilizing the hose. Meanwhile, the inflation interface 21 is used for inflating gas into the pressure-resistant sealed cavity, so that the pressure inside and outside the tube wall of the hose is kept consistent in the cleaning and sterilizing process, the elastic hose is prevented from expanding and cracking, and the loss of the elastic hose caused by cleaning and sterilizing is reduced. The pressure is increased in the space of the outer wall of the elastic hose to offset the pressure generated by the inner wall of the elastic hose due to high temperature (the temperature is higher than 120 ℃) and high pressure during cleaning and sterilization, so that the thin-wall elastic hose in the cleaning and sterilization process is comprehensively protected.
It can be understood that, in order to improve the heat preservation and pressure maintaining performance of the pressure-proof closed cavity, the inner walls of the cavity 1 and the cover body 2 of the pressure-proof closed cavity can be made of heat preservation materials with high temperature and high pressure resistance. Meanwhile, in order to improve the safety of the pressure-resistant sealed chamber, the outer walls of the chamber body 1 and the cover body 2 may be made of heat-resistant materials.
Example 3
As shown in fig. 6 and 7, the online sterilization apparatus for a filling line according to the present invention is used for performing the online sterilization method for a filling line, and has substantially the same structural arrangement and operation principle as the online sterilization apparatus in embodiment 1, and the difference is that: the top end of the cavity 1 is provided with a through boss 10 extending outwards, and the bottom end of the cavity 1 is provided with a sealing structure; the boss 10 is detachably connected with the liquid distributor 4 in a sealing manner through a fastener.
In this embodiment, through setting up cavity 1 to the structure that one end is sealed, the other end open-ended, can further improve the whole sealing performance of withstand voltage airtight chamber, also can reduce the manufacturing cost of withstand voltage airtight chamber simultaneously.
It should be noted that, in the filling system, the liquid distributor 4 and the chamber 1 may be respectively disposed at different positions of the filling equipment 8 according to actual working requirements. As shown in fig. 6, when the pipeline assembly needs to be cleaned and sterilized on line, the whole pipeline assembly consisting of the input end hose 14, the elastic hose 13, the output end hose 11 and the filling needle 15 and the liquid distributor 4 are detached from the filling equipment 8, and then the pipeline assembly is placed in the cavity 1 for cleaning and sterilizing on line. Specifically, the input end hose 14 may be fixed on a hose fixing frame 5 in the chamber 1, the filling needle 15 may be fixed on a filling needle fixing frame 6 in the chamber 1, one side of the liquid distributor 4 with the pipeline interface 41 extends into the chamber 1 from the boss 10, and the fluid inlets 42 at the two ends of the liquid distributor 4 are exposed outside the pressure-resistant sealed chamber. During the cleaning and sterilization process, high-pressure sterilization medium (such as high-temperature steam) can be simultaneously input into the pressure-resistant closed chamber through the fluid inlets 42 at the two ends of the liquid distributor 4; alternatively, the fluid inlet 42 at one end of the dispenser 4 may be sealed and the autoclave medium may be introduced into the pressure-tight chamber through the fluid inlet 42 at the other end of the dispenser 4.
In this embodiment, the liquid distributor 4 can be fixed on the boss 10 of the chamber 1 by a fastener composed of a fastening belt 18 and a bolt 19. In this embodiment, the dispenser 4 is fixed to the boss 10 by two fastening straps 18 and two sets of bolts 19, as shown in fig. 7. Wherein, the fastening belt 18 has elastic deformation capability, which further improves the connection stability of the liquid separator 4 and the cavity 1. It is understood that all fastening structures that ensure an effective and secure connection of the projection 10 to the liquid distributor 4 and that allow flexible disassembly are within the scope of the present invention.
Further, a sealing member is arranged between the boss 10 and the liquid distributor 4. Specifically, the sealing between the boss 10 and the liquid distributor 4 can be realized by using a sealing strip, or the sealing between the boss 10 and the liquid distributor 4 can be realized by manufacturing a contact sleeve on the surface of the liquid distributor 4 with sealing performance. It is understood that all configurations that ensure an effective seal between the boss 10 and the liquid distributor 4 are within the scope of the present invention.
Example 4
As shown in fig. 8, the in-line sterilization apparatus for a filling line according to the present invention is used for performing the in-line sterilization method for a filling line, and has a configuration and an operation principle substantially the same as those of the in-line sterilization apparatus of embodiment 2, and has the following differences: the top end of the cavity 1 is provided with a through boss 10 extending outwards, and the bottom end of the cavity 1 is provided with a sealing structure; the boss 10 is detachably connected with the liquid distributor 4 in a sealing manner through a fastener.
In this embodiment, through setting up cavity 1 to the structure that one end is sealed, the other end open-ended, can further improve the whole sealing performance of withstand voltage airtight chamber, also can reduce the manufacturing cost of withstand voltage airtight chamber simultaneously.
It should be noted that, in the filling system, the liquid distributor 4 and the chamber 1 may be respectively disposed at different positions of the filling equipment 8 according to actual working requirements. As shown in fig. 8, when the pipeline assembly needs to be cleaned and sterilized on line, the whole pipeline assembly consisting of the input end hose 14, the elastic hose 13, the output end hose 11 and the filling needle 15 and the liquid distributor 4 are detached from the filling equipment 8, and then the pipeline assembly is placed in the chamber 1 for cleaning and sterilizing on line. Specifically, the input end hose 14 may be fixed on the hose fixing frame 5 in the chamber 1, the filling needle 15 may be fixedly sealed in the filling needle sealing box 7 in the chamber 1, one side of the liquid separator 4 with the pipeline interface 41 extends into the chamber 1 from the boss 10, and the fluid inlets 42 at the two ends of the liquid separator 4 are exposed outside the pressure-resistant sealed chamber. During the cleaning and sterilization process, high-pressure sterilization medium (such as high-temperature steam) can be input into the pressure-resistant closed chamber through the fluid inlets 42 at the two ends of the liquid distributor 4; alternatively, the fluid inlet 42 at one end of the liquid separator 4 may be sealed, and the steam may be introduced into the pressure-tight chamber through the fluid inlet 42 at the other end of the liquid separator 4. Meanwhile, the inflation interface 21 is used for inflating air into the pressure-resistant sealed cavity, so that the pressure inside and outside the tube wall of the flexible tube is kept consistent or close to each other in the cleaning and sterilizing process, the expansion and the breakage of the elastic flexible tube are prevented, and the loss of the elastic flexible tube caused by cleaning and sterilizing is reduced.
In this embodiment, the liquid distributor 4 can be fixed on the boss 10 of the chamber 1 by a fastener composed of a fastening belt 18 and a bolt 19. Specifically, the liquid distributor 4 is fixed on the boss 10 by two fastening belts 18 and two sets of bolts 19. Wherein, the fastening belt 18 has elastic deformation capability, which further improves the connection stability of the liquid separator 4 and the cavity 1. It is understood that all fastening structures that ensure an effective and secure connection of the projection 10 to the liquid distributor 4 and that allow flexible disassembly are within the scope of the present invention.
Further, a sealing member is arranged between the boss 10 and the liquid distributor 4. Specifically, the sealing between the boss 10 and the liquid distributor 4 can be realized by using a sealing strip, or the sealing between the boss 10 and the liquid distributor 4 can be realized by manufacturing a contact sleeve on the surface of the liquid distributor 4 with sealing performance. It is understood that all configurations that ensure an effective seal between the boss 10 and the liquid distributor 4 are within the scope of the present invention.
It can be understood that, in a specific implementation process, it is also considered that the top end of the chamber 1 is provided with a sealing structure, and the bottom end of the chamber 1 is provided with a structure having a through boss 10, and the liquid distributor 4 is connected with the boss 10 at the bottom end of the chamber 1 in a sealing manner.
Example 5
As shown in fig. 9 and 10, the online sterilization apparatus for a filling line of the present invention is used for implementing the online sterilization method for a filling line, and includes a pressure-tight chamber, and further, the pressure-tight chamber includes: the liquid distributor comprises a cavity 1 and a liquid distributor 4, wherein the top end of the cavity 1 is provided with a through boss 10 extending outwards, the bottom end of the cavity 1 is provided with a sealing structure, the side part of the cavity 1 is provided with a cover door 22, and the cavity 1 and the cover door 22 are detachably and hermetically connected through a fastener; the boss 10 is fixedly connected with the liquid distributor 4 in a sealing way; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
In the embodiment, the liquid distributor 4 is fixedly connected with the cavity 1 in a sealing manner, so that the liquid distributor 4 and the cavity 1 do not need to be moved respectively in the working process, and the overall sealing performance of the pressure-resistant closed chamber is improved. Meanwhile, the side part of the cavity 1 is provided with a cover door 22, so that the pipeline assembly can conveniently enter and exit the pressure-resistant closed chamber from the cover door 22. In the process of filling work, the pipeline assembly stretches out of the pressure-resistant closed chamber from the cover door 22, corresponding metering and conveying work is carried out, when cleaning and sterilization are needed, the pipeline assembly is stored into the pressure-resistant closed chamber from the cover door 22, the cover door 22 is sealed with the cavity 1, the pipeline assembly can be cleaned and sterilized on line, and the pipeline assembly has the advantages of being good in sealing performance, easy and convenient to operate, safe, reliable and the like.
It will be appreciated that in practice, the dispenser 4 may be detachably connected to the chamber 1, for example, by bolts or elastic fastening strips to fix the dispenser 4 to the boss 10 of the chamber 1. Of course, other types of fasteners may be used to removably secure the dispenser 4 to the chamber 1. When the detachable connection mode is adopted between the liquid distributor 4 and the cavity 1, a sealing member needs to be arranged between the boss 10 and the liquid distributor 4 to ensure the integral sealing performance of the pressure-resistant closed chamber.
As shown in fig. 9 and 10, the cover door 22 is rotatably mounted at the side of the chamber 1 by a hinge 16; a filling needle sealing box 7 is arranged on the inner side wall of the cavity 1; the top of the filling needle sealing box 7 is provided with at least one filling needle fixing hole 61, the side wall of the filling needle sealing box 7 is provided with an exhaust interface 24, and the exhaust interface 24 penetrates through the side wall of the cavity 1 and is connected to the outside of the pressure-resistant closed chamber; the cover door 22 and the filling needle sealing box 7 are respectively arranged at two opposite sides of the cavity 1.
Further, the cover door 22 is rotatably mounted on the side wall of the chamber 1 by two hinges 16, and the cover door 22 is fixed on the side wall of the chamber 1 by two latches 23. It will be appreciated that the fasteners between the chamber 1 and the cover door 22 may also be snaps, bolts or screws. All fastening structures capable of ensuring the effective fixed covering of the cavity 1 and the cover door 22 and flexible disassembly are within the protection scope of the present invention. Further, a sealing member, such as a sealing strip or an inflatable sealing ring, is arranged at the covering connection position of the cover door 22 and the cavity 1. It is understood that all configurations that ensure an effective seal between the cover 22 and the chamber 1 are within the scope of the present invention.
In this embodiment, the cover door 22 is disposed along the length direction of the chamber 1, and the needle filling sealing box 7 is disposed on the upper portion of the inner side wall along the length direction of the chamber 1. Further, the filling needle sealing box 7 is provided with at least one filling needle fixing hole 61, and the side wall of the filling needle sealing box 7 is communicated with the side wall of the cavity 1 to form an exhaust port 24. Both satisfied the production demand of carrying out the cleaning and sterilizing to many pipeline subassemblies simultaneously, avoided the pipeline subassembly again to twine each other in withstand voltage airtight chamber and exist the sterilization dead angle, lead to cleaning and sterilizing not thorough, realized many pipeline subassemblies at withstand voltage airtight chamber in-order arrangement, improved the effect of pipeline subassembly cleaning and sterilizing. The sterilization medium in the pipeline assembly is discharged through the exhaust interface 24, the pressure change in the pressure-resistant sealed cavity is monitored in real time, and the use safety of the pressure-resistant sealed cavity is improved. The cover door 22 and the filling needle sealing box 7 are respectively arranged at two opposite sides of the cavity 1, so that the pipeline assembly can conveniently enter and exit the pressure-resistant closed chamber.
In the present embodiment, as shown in fig. 9, the filling needle sealing box 7 is fixed in the cavity 1 by the supporting plate 20; the filling needle 15 of the pipeline component is sealed in the filling needle sealing box 7 through the filling needle fixing hole 61; an air inflation interface 21 is arranged on the outer side wall of the cavity 1. In the online cleaning and sterilizing process of the pipeline assembly, high-pressure sterilizing medium is input into the pipeline assembly through the fluid inlet 42 of the liquid distributor 4, gas is filled into the pressure-resistant sealed cavity through the gas filling connector 21, the pressure difference between the inside and the outside of the pipe wall of the pipeline assembly is reduced, meanwhile, the sterilizing medium in the pipeline assembly is discharged through the gas discharging connector 24, the pressure change in the pressure-resistant sealed cavity is monitored in real time, and the use safety of the pressure-resistant sealed cavity is improved. It can be understood that, in the practical application process, the specific arrangement position of the inflation connector 21 on the cavity 1 is not required to be limited, as long as the inflation connector 21 can inflate the pressure-resistant sealed cavity to ensure that the internal and external pressures of the hose are the same or close to each other in the cleaning and sterilization process.
During operation, knockout 4 fixed mounting is at cavity 1 top, and pipeline interface 41 stretches into in the cavity 1, and when carrying out the filling measurement, opens the lid door 22, and input hose 14 gets into withstand voltage airtight cavity from the lid door 22 of opening in, is connected with pipeline interface 41, and the corresponding part in all the other parts and the filling equipment 8 of pipeline subassembly are connected, can measure the filling. When the pipeline assembly needs to be cleaned and sterilized, the hose connector 12 is detached from the filling equipment 8, the pipeline assembly consisting of the input end hose 14, the elastic hose 13, the output end hose 11 and the filling needle 15 is integrally contained in a pressure-resistant closed chamber from the cover door 22, and the cavity 1 and the cover door 22 are fastened through the buckle 23. In the pressure-resistant closed cavity, the filling needle 15 of the pipeline assembly is sealed in the filling needle sealing box 7, and because the outer wall of the joint of the filling needle 15 has certain elasticity, the sealing connection between the filling needle 15 and the filling needle sealing box 7 can be realized by utilizing the limiting effect of the filling needle fixing hole 61. Steam is supplied to the inlet hose 14 through the fluid inlet 42 of the dispenser 4, and the high temperature steam is supplied to the pipe assembly for cleaning and sterilizing the hose. The air is filled into the pressure-resistant sealed cavity through the air filling connector 21, so that the pressure inside and outside the tube wall of the flexible tube is kept consistent or close to each other in the cleaning and sterilizing process, the expansion and the breakage of the elastic flexible tube are prevented, and the loss of the elastic flexible tube caused by cleaning and sterilizing is reduced. The pressure is increased in the space of the outer wall of the elastic hose to offset the pressure generated by the inner wall of the elastic hose due to high temperature and high pressure during cleaning and sterilization, so that the thin-wall elastic hose in the cleaning and sterilization process is comprehensively protected. Meanwhile, steam in the pipeline assembly is firstly discharged into the filling needle sealing box 7 through the filling needle 15 and then discharged out of the pressure-resistant sealed cavity through the exhaust interface 24; the pressure change of the steam in the pipeline assembly can be monitored in real time through the exhaust interface 24, so that the steam input quantity in the pipeline assembly is properly adjusted, the cleaning and sterilizing effects of the pipeline assembly and the use safety of the pressure-resistant closed chamber are ensured, and the consumption of the steam is reduced.
Although the present invention has been described with reference to the preferred embodiments, it is not intended to be limited thereto. Those skilled in the art can make many possible variations and modifications to the disclosed embodiments, or equivalent modifications, without departing from the spirit and scope of the invention, using the methods and techniques disclosed above. Therefore, any simple modification, equivalent replacement, equivalent change and modification made to the above embodiments according to the technical essence of the present invention are still within the scope of the protection of the technical solution of the present invention.
Claims (10)
1. An online sterilization method for filling pipelines is characterized in that a pressure-resistant closed cavity is arranged on the filling pipelines, and when online sterilization is carried out, the pipelines, filling needles and joints are integrally placed into the pressure-resistant closed cavity; and introducing an autoclave medium into the pressure-resistant closed cavity, and performing online sterilization operation on the pipeline, the filling needle and the joint by using the autoclave medium.
2. The method for sterilizing the filling line in an online manner as claimed in claim 1, wherein the front end of the dispenser of the filling line is connected by a hard tube, and a pressure-resistant airtight chamber which can be opened is provided at the rear end of the dispenser together with the dispenser; the pipeline interface of knockout is in withstand voltage airtight cavity, and the space in withstand voltage airtight cavity is used for placing knockout rear end pipeline and irritates the needle.
3. The method for sterilizing the filling pipeline on line according to claim 1, wherein the pressure-resistant closed chamber is provided with a quick clamping joint hole for installing a drain valve and a pressure gauge at the sterilization tail end, or the quick clamping joint hole is directly connected with other sterilization pipelines for online sterilization.
4. An online sterilization device for filling pipelines, which is characterized by comprising a pressure-resistant closed chamber, wherein the pressure-resistant closed chamber comprises: the device comprises a cavity (1), a cover body (2) and a liquid distributor (4); the top end and the bottom end of the cavity (1) are communicated, and the top end of the cavity (1) is detachably and hermetically connected with the cover body (2) through a fastener; the bottom end of the cavity (1) is provided with a boss (10) extending outwards, and the boss (10) is detachably and hermetically connected with the liquid distributor (4) through a fastener; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
5. An online sterilization device for filling pipelines, which is characterized by comprising a pressure-resistant closed chamber, wherein the pressure-resistant closed chamber comprises: a cavity (1) and a liquid distributor (4); the top end of the cavity (1) is provided with a through boss (10) extending outwards, and the bottom end of the cavity (1) is provided with a sealing structure; the boss (10) is detachably connected with the liquid distributor (4) in a sealing manner through a fastener; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
6. An online sterilization device for filling pipelines, which is characterized by comprising a pressure-resistant closed chamber, wherein the pressure-resistant closed chamber comprises: the liquid distributor comprises a cavity (1) and a liquid distributor (4), wherein a through boss (10) extending outwards is arranged at the top end of the cavity (1), the bottom end of the cavity (1) is of a sealing structure, a cover door (22) is arranged on the side part of the cavity (1), and the cavity (1) and the cover door (22) are detachably and hermetically connected through a fastener; the boss (10) is fixedly connected with the liquid distributor (4) in a sealing way; when online sterilization is carried out, the pipeline assembly of the filling system is placed in the pressure-resistant sealed cavity, and high-pressure sterilization medium is input into the pressure-resistant sealed cavity through the pipeline assembly.
7. The device for the on-line sterilization of filling lines according to claim 4, 5 or 6, wherein the dispenser (4) is provided with at least one line connection (41), and the dispenser (4) is further provided with at least one fluid inlet (42); the pipeline interface (41) and the fluid inlet (42) are respectively positioned on different sides of the liquid distributor (4); when online sterilization is carried out, the pipeline interface (41) extends into the cavity (1).
8. The online sterilization device for the filling pipeline according to claim 7, wherein a hose fixing frame (5) and a filling needle fixing frame (6) are respectively arranged on two inner side walls of the cavity (1); the hose fixing frame (5) is provided with at least one hose fixing groove (51), and the filling needle fixing frame (6) is provided with at least one filling needle fixing hole (61).
9. The online sterilization device for the filling pipeline according to claim 7, wherein a hose fixing frame (5) and a filling needle sealing box (7) are respectively arranged on two inner side walls of the cavity (1); the hose fixing frame (5) is provided with at least one hose fixing groove (51), and the top of the filling needle sealing box (7) is provided with at least one filling needle fixing hole (61); a filling needle (15) of the pipeline assembly is sealed in the filling needle sealing box (7) through the filling needle fixing hole (61); and an inflation connector (21) is arranged on the outer side wall of the cavity (1).
10. The device for the in-line sterilization of the filling line according to claim 7, characterized in that said cover door (22) is rotatably mounted on the side of the chamber (1) by means of a hinge (16); a filling needle sealing box (7) is arranged on the inner side wall of the cavity (1); the top of the filling needle sealing box (7) is provided with at least one filling needle fixing hole (61), and a filling needle (15) of the pipeline assembly is sealed in the filling needle sealing box (7) through the filling needle fixing hole (61); an exhaust interface (24) is arranged on the side wall of the needle filling sealing box (7), and the exhaust interface (24) penetrates through the side wall of the cavity (1) and is connected to the outside of the pressure-resistant closed chamber; and an inflation connector (21) is arranged on the outer side wall of the cavity (1).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010746496.2A CN111792119A (en) | 2020-07-29 | 2020-07-29 | Online sterilization method and device for filling pipeline |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010746496.2A CN111792119A (en) | 2020-07-29 | 2020-07-29 | Online sterilization method and device for filling pipeline |
Publications (1)
Publication Number | Publication Date |
---|---|
CN111792119A true CN111792119A (en) | 2020-10-20 |
Family
ID=72828315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010746496.2A Pending CN111792119A (en) | 2020-07-29 | 2020-07-29 | Online sterilization method and device for filling pipeline |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111792119A (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1030349A (en) * | 1962-12-17 | 1966-05-18 | Rud A Hartmann Gross App Und S | Apparatus for continuously sterilising various products in large institutions, particularly hospitals |
CN202030076U (en) * | 2011-04-14 | 2011-11-09 | 长沙汇一制药机械有限公司 | On-line sterilization air chamber |
CN103230908A (en) * | 2013-04-24 | 2013-08-07 | 楚天科技股份有限公司 | Water tank assembly for irrigating needle online cleaning and sterilizing |
CN203170647U (en) * | 2013-04-24 | 2013-09-04 | 楚天科技股份有限公司 | Water tank component used for on-line cleaning and sterilization of feeding syringe |
CN212767163U (en) * | 2020-07-29 | 2021-03-23 | 湖南执先科技有限公司 | Online sterilization device for filling pipeline |
-
2020
- 2020-07-29 CN CN202010746496.2A patent/CN111792119A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1030349A (en) * | 1962-12-17 | 1966-05-18 | Rud A Hartmann Gross App Und S | Apparatus for continuously sterilising various products in large institutions, particularly hospitals |
CN202030076U (en) * | 2011-04-14 | 2011-11-09 | 长沙汇一制药机械有限公司 | On-line sterilization air chamber |
CN103230908A (en) * | 2013-04-24 | 2013-08-07 | 楚天科技股份有限公司 | Water tank assembly for irrigating needle online cleaning and sterilizing |
CN203170647U (en) * | 2013-04-24 | 2013-09-04 | 楚天科技股份有限公司 | Water tank component used for on-line cleaning and sterilization of feeding syringe |
CN212767163U (en) * | 2020-07-29 | 2021-03-23 | 湖南执先科技有限公司 | Online sterilization device for filling pipeline |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN212767163U (en) | Online sterilization device for filling pipeline | |
JPS6176807A (en) | Double sealing type nozzle-dam | |
CN111792119A (en) | Online sterilization method and device for filling pipeline | |
CN208109586U (en) | A kind of combustion gas stainless steel corrugated flexible hose and device for testing tensile force | |
CN114135476A (en) | Pump detection device | |
CN212924366U (en) | High-pressure box for online sterilization of peristaltic pump hose and peristaltic pump filling system | |
CN214465372U (en) | Adjustable hardware sleeve convenient to connect | |
CN209794325U (en) | Rubber tube water injection shedder | |
CN212007697U (en) | High-pressure airtightness detection device for hose | |
CN111963815A (en) | Petroleum pipeline breach block structure | |
CN217978377U (en) | Clinical treatment hydrogen conveying pipeline | |
CN111306395A (en) | Online repair system and repair method for pipeline assembly after sealing failure | |
CN110894902A (en) | Telescopic crawling robot in pneumatic pipe | |
CN220983070U (en) | Plastic pipe vibration testing device | |
CN213466559U (en) | Protection device for aseptic weighing equipment | |
CN219214012U (en) | Portable detection device in injection mold water route | |
CN211739363U (en) | Mobile air conditioner chilled water flushing device with filtering capacity | |
CN213192809U (en) | Filter element detection system for infusion bag production | |
CN216955016U (en) | Detection device is used in gas table production | |
CN217030821U (en) | Large-scale turbo generator gas replacement device | |
CN208476476U (en) | A kind of efficient air-tightness detection device | |
CN220751516U (en) | Auxiliary workpiece for pressurizing test for environment-friendly equipment outgoing installation | |
CN213637411U (en) | Bushing equipment of flattening in shielding motor | |
CN219055033U (en) | Oil supplementing device of oil temperature control system | |
CN219200734U (en) | Novel combined device for performance test of semiconductor accessories |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |