CN111777022B - Filling device - Google Patents
Filling device Download PDFInfo
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- CN111777022B CN111777022B CN202010688928.9A CN202010688928A CN111777022B CN 111777022 B CN111777022 B CN 111777022B CN 202010688928 A CN202010688928 A CN 202010688928A CN 111777022 B CN111777022 B CN 111777022B
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- solid
- filling
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- cup
- pneumatic valve
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/28—Flow-control devices, e.g. using valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/26—Filling-heads; Means for engaging filling-heads with bottle necks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/26—Filling-heads; Means for engaging filling-heads with bottle necks
- B67C2003/2671—Means for preventing foaming of the liquid
Abstract
The invention provides a filling device which comprises a solid-liquid quantifying cup, a solid quantifying cup, filling pipelines sequentially connected with a material storage container, the solid-liquid quantifying cup, the solid quantifying cup and a filling head, a liquid inlet pipeline connected with the upper part of the solid quantifying cup, a compressed air pipeline connecting a gas source with the upper part of the solid-liquid quantifying cup and the upper part of the material storage container respectively, drainage pipelines connected with the lower part of the solid quantifying cup, the upper part of the solid-liquid quantifying cup and the upper part of the filling head respectively, and exhaust pipelines connected with the upper part of the solid quantifying cup and the upper part of the solid-liquid quantifying cup respectively, wherein each pipeline is provided with a valve for controlling the opening and closing of the pipeline so as to realize. The adoption is earlier decided and holds the adsorbent, and the reuse storage liquid washes, carries out the mode of filling along with the adsorbent, carries out the constant volume of storage liquid through the interface of draining on the filling head, solves the accurate filling of adsorbent and storage liquid, and the potential safety hazard that the filling in-process bubble brought has also been solved to the mode of filling after the constant volume.
Description
Technical Field
The invention relates to the technical field of medical equipment filling equipment, in particular to a filling device applied to a blood purification perfusion device.
Background
Hemoperfusion (HP), also called blood adsorption, refers to the process of whole blood flowing through an perfusion apparatus, contacting with a solid phase adsorbent, removing endogenous or exogenous toxins, such as uremic toxins and excess drugs, by adsorption, and then returning the purified blood to the patient for treatment.
The perfusion device is of a tank structure, at present, a filling machine on the market is only suitable for filling of a single substance, if the filling machine respectively fills the adsorbent and the storage liquid in the same perfusion device, a large amount of bubbles exist in the perfusion device, the bubble is difficult to remove, and safety hidden troubles are brought when the perfusion device is used. Therefore, a filling device capable of filling the storage liquid along with the adsorbent is needed, so that the adsorbent and the storage liquid can be accurately filled, and the potential safety hazard caused by bubbles in the filling process can be solved.
Disclosure of Invention
The purpose of the invention is: the utility model provides a filling device for blood purifies perfusion ware solves the accurate filling that adsorbent and stock solution mix and the potential safety hazard that the filling in-process bubble brought.
In order to achieve the above object, the present invention provides a filling device, wherein the filling device body 100 comprises:
the storage container is used for storing a mixture of the solid adsorbent and the storage solution;
the filling head 101 is used for being connected with the perfusion device to fill the adsorbent;
a solid quantifying cup 103 for quantifying the solid adsorbent;
a solid-liquid quantifying cup 104 for quantifying a mixture of the solid adsorbent and the storage solution;
the filling pipeline is sequentially connected with the material storage container, the solid-liquid quantifying cup 104, the solid quantifying cup 103 and the filling head 101;
a liquid inlet pipeline connected with the upper part of the solid quantifying cup 103;
a compressed air pipeline which connects an air source with the upper part of the storage container and the upper part of the solid-liquid quantitative cup 104 respectively;
the drainage pipeline is respectively connected with the lower part of the solid quantifying cup 103, the upper part of the solid quantifying cup 104 and the upper part of the filling head 101;
and an exhaust pipe connected to the upper part of the solid-liquid measuring cup 103 and the upper part of the solid-liquid measuring cup 104, respectively.
Preferably, the first and second electrodes are formed of a metal,
and a filling pneumatic valve 110 for controlling the start of filling is arranged on the filling pipeline.
The liquid inlet pipeline is provided with a liquid inlet pneumatic valve 106 for controlling the liquid inlet quantity.
The compressed air pipe is provided with a compressed air pneumatic valve 107 for controlling the supply of compressed air.
The drainage pipeline connected with the upper part of the filling head 101 is provided with a first drainage pneumatic valve 108a, and the drainage pipeline connected with the lower part of the solid dosing cup 103 is provided with a second drainage pneumatic valve 108b for controlling the drainage amount in the filling process.
The first exhaust air-operated valve 109a is provided in the exhaust pipe connected to the upper part of the solid content cup 103, and the second exhaust air-operated valve 109b is provided in the exhaust pipe connected to the upper part of the solid content cup 104 to control the air pressure in the apparatus.
Preferably, the filling head 101 and the exhaust line are provided with a lifting cylinder 102 controlling its docking with the cartridge. Automatic control is realized, and the filling head 101 is in accurate butt joint with the perfusion apparatus.
Preferably, the upper part of the solid-liquid quantitative cup 104 is provided with a liquid level detector 105. The adsorbent mixture in the solid-liquid quantitative cup 104 is accurately fixed in volume.
Preferably, the solid-liquid quantitative cup 104 is provided with a solid-liquid quantitative regulating valve for regulating the solid-liquid mixture dosage, and the solid quantitative cup 103 is provided with a solid quantitative regulating valve for regulating the solid adsorbent dosage. The filling machine is suitable for filling of filling machines of different models.
Preferably, the lower end of the solid measuring cup 103 is provided with a filter screen structure. The adsorbent and solution are separated as the liquid is discharged.
A filling method is suitable for the filling device of the invention, and comprises the following steps:
the filling device is respectively communicated with the filling head 101 and the drainage pipeline;
opening a compressed air pneumatic valve at the upper part of the material storage container and an exhaust pneumatic valve II 109b at the upper part of the solid-liquid quantifying cup 104, opening a control valve of the material storage container, and pressing the solid adsorbent and the storage solution into the solid-liquid quantifying cup 104;
when the liquid level at the upper part of the solid-liquid quantitative cup 104 reaches a preset liquid level, closing a compressed air pneumatic valve at the upper part of the storage container, a second exhaust pneumatic valve 109b of the solid-liquid quantitative cup 104 and a control valve of the storage container;
then, opening a compressed air pneumatic valve 107, a material transfer pneumatic valve 111, an exhaust pneumatic valve 109a and a drain pneumatic valve 108b, pressing the quantified solid adsorbent and the storage solution into the solid quantifying cup 103, discharging the storage solution from a drainage pipeline at the lower part of the solid quantifying cup 103, and retaining the solid adsorbent in the solid quantifying cup 103 for quantification;
the first solid adsorbent quantitative closing exhaust pneumatic valve 109a, the material transfer pneumatic valve 111, the compressed air pneumatic valve 107 and the second drainage pneumatic valve 108 b;
opening the liquid inlet pneumatic valve 106 and the filling pneumatic valve 110, and filling the solid adsorbent into the column of the perfusion apparatus by the liquid in the liquid inlet pipeline at the upper part of the solid quantifying cup 103;
when the perfusion apparatus is filled, a drainage pipeline at the lower part of the perfusion apparatus is closed, a drainage pneumatic valve I108 a is opened, liquid in the column body of the perfusion apparatus is drained from the drainage pipeline opened by the filling head 101, and the liquid in the column body of the perfusion apparatus is quantified, so that bubbles can be prevented from being generated in the filling process of the solid adsorbent and the liquid;
after filling, the inlet pneumatic valve 106, the filling pneumatic valve 110 and the drain pneumatic valve 108a are closed.
Preferably, at the beginning of filling, the lifting cylinder 102 is activated, and the filling head 101 and the drain pipes of the filling element are lowered and connected to the filling element, respectively.
A filling machine is provided with the filling device.
The embodiment of the invention has the beneficial effects that: by arranging two groups of quantitative devices of the solid-liquid quantitative cup 104 and the solid-liquid quantitative cup 103 and matching with the design of quantitative and filling methods, the mode of firstly determining the volume of the adsorbent, then flushing the adsorbent by using the storage liquid and then filling the adsorbent together is realized. The storage liquid in the filling device is filled along with the solid adsorbent, so that the accurate filling of the solid adsorbent and the storage liquid can be realized, and the potential safety hazard caused by bubbles in the filling process can be avoided.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
in the figure, 100, a filling device body, 101, a filling head, 102, a lifting cylinder, 103, a solid quantitative cup, 104, a solid quantitative cup, 105, a liquid level detector, 106, an inlet pneumatic valve, 107, a compressed air pneumatic valve, 108a, a first drain pneumatic valve, 108b, a second drain pneumatic valve, 109a, a first exhaust pneumatic valve, 109b, a second exhaust pneumatic valve, 110, a filling pneumatic valve, 111, a material transfer pneumatic valve,
Detailed Description
The following detailed description of embodiments of the present invention is provided in connection with the accompanying drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
It will be understood that when an element is referred to as being "disposed on," "corresponding to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "secured to" or "fixedly coupled" to another element, it can be removably secured or non-removably secured to the other element. When an element is referred to as being "connected," "pivotally connected," to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," "up," "down," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.
In the description of the present invention, it should be understood that the terms "SIP pipe" and "CIP pipe" are used in the present invention:
in-line Cleaning (CIP) is used for cleaning and purifying production equipment with strict requirements on sanitary level by applying a strong action to equipment and devices by using a high-temperature and high-concentration cleaning solution without disassembling or moving the devices. It is widely used in the production of pharmacy, beverage, dairy products, fruit juice, wine and the like with higher mechanization degree.
In-line Sterilization (SIP), clean steam must be used for sterilization, i.e., saturated pure steam generated by a pure steam generator must be used for sterilization. The system consists of a sterilization chamber, a water ring pump, a valve, a pipeline, a temperature control system and a pressure control system.
As shown in fig. 1, in the filling device according to the embodiment of the present invention, the filling device 100 includes a solid-liquid quantitative cup 104, a solid-liquid quantitative cup 103, a filling pipe, a liquid inlet pipe, a compressed air pipe, a drain pipe, and an exhaust pipe, the filling pipe is sequentially connected to a filling head 101, the solid-liquid quantitative cup 103, the solid-liquid quantitative cup 104, and a storage container, and the liquid inlet pipe is connected to an upper portion of the solid-liquid quantitative cup 103.
In one embodiment of the present invention, the filling pipeline is provided with a filling pneumatic valve 110 for controlling the start and stop of filling; the liquid inlet pipeline is provided with a liquid inlet pneumatic valve 106 for controlling the liquid inlet amount; a compressed air pipeline is connected with the upper part of the solid-liquid quantitative cup 104, and a compressed air pneumatic valve 107 is arranged on the compressed air pipeline to control the supply of compressed air; the drainage pipeline is connected with the lower part of the solid quantitative cup 103, and a second drainage pneumatic valve 108b is arranged on the drainage pipeline; the drainage pipeline is connected with the upper part of the solid-liquid quantitative cup 104; the drainage pipeline is connected with the upper part of the filling head 101, and a drainage pneumatic valve 108a is arranged on the drainage pipeline to control the drainage amount in the filling process; the exhaust pipeline is connected with the upper part of the solid quantifying cup 103 and is provided with an exhaust pneumatic valve I109 a; the exhaust pipeline is connected with the upper part of the solid-liquid quantifying cup 104, the exhaust pipeline is provided with an exhaust pneumatic valve II 109b, and the two exhaust pneumatic valves are mainly used for controlling the air pressure in the equipment; in particular, the second exhaust air-operated valve 109b is also used when the solid-liquid quantitative cup 104 discharges water.
In one embodiment of the invention, the filling head 101 and the drainage pipeline of the perfusion device are controlled by the lifting cylinder 102, and when filling is started, the filling head 101 and the drainage pipeline of the perfusion device descend to the top surface of the perfusion device to realize butt joint with the perfusion device.
In one embodiment of the invention, the upper part of the solid-liquid quantitative cup 104 of the filling device is provided with a liquid level detector 105, and in the filling process, when the liquid level reaches the position designated by the liquid level detector 105, the liquid level detector 105 feeds back a signal, a control valve of a storage container is closed, and the transfer of the adsorbent is stopped.
In one embodiment of the present invention, the solid dosing cup 103 and the solid-liquid dosing cup 104 are provided with a regulating valve, i.e., a solid-liquid dosing regulating valve for regulating the amount of the solid-liquid mixture and a solid dosing regulating valve for regulating the amount of the solid adsorbent. Through adjusting two quantitative governing valves, can realize the filling to different specification models perfusion ware.
In one embodiment of the present invention, the lower end of the solid measuring cup 103 is a filter screen structure, and the aperture of the filter screen is smaller than the particle size of the adsorbent, so that water can be discharged from the solid measuring cup 103 along with the drainage pipe, and the adsorbent is retained in the solid measuring cup 103 for measuring the quantity.
The filling machine provided by the embodiment of the invention mainly comprises a storage container, a filling device, a conveying belt, a cover screwing device, a lower drainage mechanism and a rack. The conveyer belt is provided with a clamp for fixing one end of the sealed filler, the conveyer belt can move to the filling position and the cap rotating position at equal intervals relative to the frame, the clamps are arranged on the conveyer belt at equal intervals, the lower part of the clamp is provided with a spring type sealing structure, and the clamp is made of a preferred polymer nylon. The tail end of the conveying belt is provided with an induction probe, and when the induction probe detects the filling machine, the whole filling machine is automatically and emergently stopped. The frame is provided with a lower drainage mechanism which is used for being in sealing fit with the lower part of the clamp, the lower drainage mechanism and the filling head 101 are relatively vertically distributed, the lower drainage mechanism can vertically move up and down at equal distance, the lower drainage mechanism is provided with a drainage valve and a lifting controller, and when the clamp moves to a filling position, the lower drainage mechanism vertically moves up through the lifting controller and is in sealing fit with the lower part of the clamp. The lower drainage mechanism can also be provided with a push rod matched with the spring type sealing structure at the lower part of the clamp, when the lower drainage mechanism is matched with the lower part of the clamp in a sealing way, the push rod in the lower drainage mechanism pushes and presses the spring type sealing structure at the lower part of the clamp to remove the sealing, and the lower drainage is carried out in the filling process of the perfusion apparatus. The upper part of the storage container is provided with a compressed air pipeline, an SIP pipeline and a CIP pipeline, and the compressed air pipeline is provided with a control valve for controlling compressed air to transfer the adsorbent; the SIP pipeline is provided with an SIP pneumatic valve for controlling the on-line sterilization of the storage container, and the pipeline is provided with a CIP pneumatic valve for controlling the on-line cleaning of the storage container. The storage container is provided with a stirrer with adjustable rotating speed and is used for enabling the solid adsorbent and the storage solution to be in a uniform suspension state under the action of the stirrer. The rack is provided with a driving mechanism for driving the conveying belt to move equidistantly.
In one embodiment of the invention, when a filling machine carries out filling, a stirrer of a storage container is started to enable a solid adsorbent and a storage solution to be in a uniform suspension state, one end of a cylinder of a perfusion apparatus is assembled, the assembled end of the cylinder of the perfusion apparatus is placed into a clamp to be fixed, a driving mechanism is started, the clamp fixed with the perfusion apparatus is moved to a filling position, a filling head 101 moves downwards through a lifting cylinder 102 to tightly press the upper end of the cylinder of the perfusion apparatus, a lower drainage mechanism moves upwards through a lifting controller to be in sealing fit with the lower part of the clamp, a compressed air pneumatic valve at the upper part of the storage container and an exhaust pneumatic valve II 109b at the upper part of a solid-liquid quantitative cup 104 are opened, a control valve of the storage container is opened, and the solid adsorbent and the storage solution; when the liquid level detector 105 on the upper part of the solid-liquid quantitative cup 104 senses a liquid level, the liquid level detector 105 feeds back a signal, the compressed air pneumatic valve on the upper part of the material storage container, the exhaust pneumatic valve II 109b on the upper part of the solid-liquid quantitative cup 104 and the material storage container control valve are closed, the solid adsorbent and the storage solution are stopped to be transferred, and the quantification of the solid adsorbent and the storage solution is completed; then automatically opening a second lower water discharge pneumatic valve 108b, a first upper exhaust pneumatic valve 109a, a material transfer pneumatic valve 111 and a compressed air pneumatic valve 107 at the upper part of the solid-liquid quantifying cup 104 of the solid quantifying cup 103, pressing the quantified solid adsorbent and the storage solution into the solid quantifying cup 103, discharging the storage solution from a drainage pipeline at the lower part of the solid quantifying cup 103, and reserving the solid adsorbent in the solid quantifying cup 103 for quantification; after the solid adsorbent is quantitatively filled, the second water discharge pneumatic valve 108b, the first gas discharge pneumatic valve 109a, the material transfer pneumatic valve 111 and the compressed air pneumatic valve 107 are closed, the water discharge valves of the liquid inlet pneumatic valve 106, the filling pneumatic valve 110 and the lower water discharge mechanism on the upper part of the solid dosing cup 103 are automatically opened, the solid adsorbent is flushed into the cartridge of the perfusion apparatus through liquid in the liquid inlet pipeline on the upper part of the solid dosing cup 103, the liquid is discharged through the water discharge pipeline of the lower water discharge mechanism, when the cartridge of the perfusion apparatus is filled, the water discharge valve of the lower water discharge mechanism is closed, the first water discharge pneumatic valve 108a of the filling head 101 is opened, the liquid in the cartridge of the perfusion apparatus is discharged from the water discharge pipeline of the filling head 101, the liquid in the cartridge of the perfusion apparatus is quantitatively determined, after the filling is completed, the liquid inlet pneumatic valve 106, the filling pneumatic valve 110 and the first water discharge pneumatic valve 108a of the filling head 101 are closed, the, and (3) recovering a spring type sealing structure at the lower part of the clamp, pre-assembling the upper end of the cylinder of the perfusion device, starting the driving mechanism, moving the conveying belt, moving the filled cylinder of the perfusion device to a cover rotating position for cover rotating, and completing the whole filling process.
In summary, the embodiments of the present invention provide a filling device, a filling method and a filling machine having the filling device of the present invention. The filling device mainly comprises a solid-liquid quantitative cup, a solid quantitative cup, a filling pipeline, a liquid inlet pipeline, a compressed air pipeline, a drainage pipeline and an exhaust pipeline, wherein each pipeline is provided with a valve for controlling the pipeline to be opened and closed so as to realize the operation control of different steps in the filling process. The filling step mainly comprises the steps of communicating a filling device and a perfusion device, quantifying the adsorbent mixture in a solid-liquid quantifying cup, transferring the adsorbent mixture to the solid quantifying cup, discharging liquid in the solid quantifying cup, quantifying the solid adsorbent in the solid quantifying cup, filling the solid adsorbent to a perfusion device by using storage liquid, quantifying the storage liquid in the perfusion device, and completing filling. The adsorbent is firstly subjected to volume fixing, then the storage liquid is washed, and the adsorbent is filled together with the adsorbent, the volume fixing of the storage liquid is carried out through the water discharging interface on the filling head, so that the problem of accurate filling of the adsorbent and the storage liquid is solved, and the potential safety hazard caused by bubbles in the filling process is also solved through the filling mode after the volume fixing.
The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and substitutions can be made without departing from the technical principle of the present invention, and these modifications and substitutions should also be regarded as the protection scope of the present invention.
Claims (7)
1. A filling device, its characterized in that: a filling device body (100) comprising
The storage container is used for storing a mixture of the solid adsorbent and the storage solution;
the filling head (101) is connected with the perfusion device to fill the adsorbent;
the solid quantifying cup (103) is used for quantifying the solid adsorbent, and the lower end of the solid quantifying cup (103) is provided with a filter screen structure;
a solid-liquid quantifying cup (104) for quantifying the mixture of the solid adsorbent and the storage solution;
the filling pipeline is sequentially connected with the material storage container, the solid-liquid quantitative cup (104), the solid quantitative cup (103) and the filling head (101);
a liquid inlet pipeline connected with the upper part of the solid quantifying cup (103);
the compressed air pipeline is used for respectively connecting an air source with the upper part of the material storage container and the upper part of the solid-liquid quantitative cup (104);
the drainage pipeline is respectively connected with the lower part of the solid quantifying cup (103), the upper part of the solid quantifying cup (104) and the upper part of the filling head (101);
and an exhaust pipe connected to the upper part of the solid-liquid measuring cup (103) and the upper part of the solid-liquid measuring cup (104), respectively.
2. The filling device according to claim 1, wherein:
a filling pneumatic valve (110) for controlling the start of filling is arranged on the filling pipeline;
a material transfer pneumatic valve (111) is also arranged on the filling pipeline, and the material transfer pneumatic valve (111) is positioned between the solid quantitative cup (103) and the solid quantitative cup (104);
the liquid inlet pipeline is provided with a liquid inlet pneumatic valve (106) for controlling the liquid inlet quantity;
a compressed air pneumatic valve (107) for controlling the supply of compressed air is arranged on the compressed air pipeline;
a first drainage pneumatic valve (108a) is arranged on a drainage pipeline connected with the upper part of the filling head (101), and a second drainage pneumatic valve (108b) for controlling the drainage quantity in the filling process is arranged on a drainage pipeline connected with the lower part of the solid quantitative cup (103);
the exhaust pipe connected to the upper part of the solid-liquid quantitative cup (103) is provided with a first exhaust air-operated valve (109a), and the exhaust pipe connected to the upper part of the solid-liquid quantitative cup (104) is provided with a second exhaust air-operated valve (109b) for controlling the air pressure in the apparatus.
3. The filling apparatus according to claim 1 or 2, wherein: and the filling head (101) and an exhaust pipeline of the perfusion device are provided with a lifting cylinder (102) for controlling the filling head to be in butt joint with the perfusion device.
4. A filling device according to claim 3, wherein: the upper part of the solid-liquid quantitative cup (104) is provided with a liquid level detector (105).
5. A filling device according to claim 3, wherein: the solid-liquid quantitative cup (104) is provided with a solid-liquid quantitative regulating valve for regulating the solid-liquid mixed dosage, and the solid quantitative cup (103) is provided with a solid quantitative regulating valve for regulating the solid adsorbent dosage.
6. A filling method according to claim 2, wherein:
the filling device is respectively communicated with the filling head (101) and the drainage pipeline,
opening a compressed air pneumatic valve at the upper part of the storage container and an exhaust pneumatic valve II (109b) at the upper part of the solid-liquid quantitative cup (104), opening a control valve of the storage container, pressing the solid adsorbent and the storage solution into the solid-liquid quantitative cup (104),
when the liquid level at the upper part of the solid-liquid quantitative cup (104) reaches a preset liquid level, the compressed air pneumatic valve, the exhaust pneumatic valve II (109b) and the storage container control valve at the upper part of the storage container are closed,
then opening a compressed air pneumatic valve (107), a material transfer pneumatic valve (111), an exhaust pneumatic valve I (109a) and a drain pneumatic valve II (108b), pressing the quantified solid adsorbent and the storage solution into the solid quantitative cup (103), discharging the storage solution from a drainage pipeline at the lower part of the solid quantitative cup (103), leaving the solid adsorbent in the solid quantitative cup (103) for quantification,
the first exhaust pneumatic valve (109a), the material transfer pneumatic valve (111) and the compressed air pneumatic valve (107) are closed after the solid adsorbent is quantitatively determined,
opening the liquid inlet pneumatic valve (106) and the filling pneumatic valve (110), flushing the solid adsorbent into the cylinder of the perfusion apparatus by the liquid in the liquid inlet pipeline at the upper part of the solid quantifying cup (103),
when the perfusion apparatus is filled, the first drainage pneumatic valve (108a) is opened, the liquid in the column body of the perfusion apparatus is drained from the drainage pipeline opened by the filling head (101) to carry out liquid quantification in the column body of the perfusion apparatus,
after filling, the inlet pneumatic valve (106), the filling pneumatic valve (110) and the first drainage pneumatic valve (108a) are closed.
7. A filling machine, its characterized in that: a filling device according to any one of claims 1-5 is provided.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010688928.9A CN111777022B (en) | 2020-07-16 | 2020-07-16 | Filling device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010688928.9A CN111777022B (en) | 2020-07-16 | 2020-07-16 | Filling device |
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| CN111777022A CN111777022A (en) | 2020-10-16 |
| CN111777022B true CN111777022B (en) | 2021-03-05 |
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Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1177718A (en) * | 1981-04-16 | 1984-11-13 | Masaru Kawahashi | Line for use in body fluid treatment |
| JPH0744948B2 (en) * | 1987-03-20 | 1995-05-17 | 川澄化学工業株式会社 | Method for manufacturing container containing chemical liquid |
| ES1024044Y (en) * | 1993-03-16 | 1994-04-01 | Grifols Lucas | MACHINE FOR STERILE FILLING AND ITS CHECKING, OF STERILE BAGS FOR PERFUSION LIQUIDS. |
| US20050261619A1 (en) * | 2004-05-24 | 2005-11-24 | Terumo Cardiovascular Systems Corporation | Vortex-flow air removal in a blood perfusion system |
| DE102007009269B4 (en) * | 2007-02-26 | 2010-11-11 | Fresenius Medical Care Deutschland Gmbh | Device and method for filling and / or emptying a dialysis machine |
| CN201643086U (en) * | 2010-04-09 | 2010-11-24 | 山东省千佛山医院 | Special connecting pipe for blood perfusion use |
| DE102014006821B4 (en) * | 2014-05-08 | 2021-08-26 | Fresenius Medical Care Deutschland Gmbh | Method for filling a container in the dialysis machine |
| CN205346805U (en) * | 2015-12-11 | 2016-06-29 | 常州华岳微创医疗器械有限公司 | Full automatic filling equipment of hemodialysis concentrate |
| CN206751365U (en) * | 2017-05-25 | 2017-12-15 | 武汉柯瑞迪医疗用品有限公司 | A kind of filling head of haemodialysis B liquid |
| CN208053779U (en) * | 2018-03-07 | 2018-11-06 | 廊坊市爱尔血液净化器材厂 | Has the blood perfusion device filling liquid device for casting of on-line cleaning and sterilizing function |
| CN108862168A (en) * | 2018-07-02 | 2018-11-23 | 江苏纳海生物科技有限公司 | A kind of hemodialysis concentrated solution conveying bulking system |
| CN109625362B (en) * | 2018-12-17 | 2020-12-25 | 成都合达自动化设备有限公司 | Vacuum lossless solid-liquid mixing and filling equipment |
| CN110314259A (en) * | 2019-07-24 | 2019-10-11 | 广州康盛生物科技有限公司 | Perfusion device |
| CN110482248B (en) * | 2019-08-26 | 2021-07-06 | 北京中科太康科技有限公司 | Adsorbent filling device and filling method |
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2020
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