CN212833762U - Human prothrombin complex adsorption test device - Google Patents
Human prothrombin complex adsorption test device Download PDFInfo
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- CN212833762U CN212833762U CN202021492148.9U CN202021492148U CN212833762U CN 212833762 U CN212833762 U CN 212833762U CN 202021492148 U CN202021492148 U CN 202021492148U CN 212833762 U CN212833762 U CN 212833762U
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Abstract
The utility model discloses a human prothrombin complex adsorption test device belongs to bio-pharmaceuticals test equipment technical field. The device comprises a tank body and an aeration component, wherein a feed port is formed in the top of the tank body, a sealing cover is arranged at the feed port on the tank body, a filtering sieve plate is arranged in the tank body, a reagent feeding component is arranged above the filtering sieve plate in the tank body, a liquid drainage component is arranged below the filtering sieve plate on the tank body, and the aeration component is positioned outside the tank body and is connected with the bottom of the tank body. The testing device has the advantages of simple structure and low manufacturing cost. Compressed air is intermittently blown into the tank body by using an air pump, so that the aim of stirring the blood plasma and the gel is fulfilled. Because the diameter of the upper part of the tank body is larger than that of the lower part, the materials thrown into the tank body can be gathered at the bottom of the tank body, so that the mixed liquid containing PCC required by the test can be obtained by throwing a small amount of materials, and the test cost is low.
Description
Technical Field
The utility model relates to a human prothrombin complex adsorption test device belongs to bio-pharmaceuticals test equipment technical field.
Background
Human prothrombin complex (PCC for short) is a trace protein contained in human plasma and is clinically used for treating hemophilia b. The existing equipment for separating PCC by adsorption mainly comprises an adsorption tank and an expanded bed, wherein the adsorption tank is a batch processing equipment and can only complete the adsorption of PCC in plasma, and the separation of PCC needs another chromatographic column to complete. The expanded bed can realize that the adsorption separation of the PCC is completed in the same equipment, but the equipment for the adsorption separation of the PCC needs special adsorption media.
Chinese patent publication No. CN104328036A discloses a human prothrombin compound adsorption separation device, which comprises a tank body and a stirring part, wherein the tank body is provided with a buffer solution distribution pipe and a feed pipe, the buffer solution distribution pipe and the feed pipe extend into the tank body from the top of the tank body, and the top of the tank body is further provided with a manhole; the tank body bottom be provided with the tank bottoms board that can open and shut, tank bottoms board top be provided with the filter plate, tank bottoms board bottom be provided with the tank bottoms valve. The adsorption separation of the human prothrombin compound is completed in the same equipment, the operation time is saved, the risk of product pollution is reduced, the open type operation in the production process is avoided, and the closed type operation is realized.
However, this apparatus is disadvantageous in that it has a complicated structure and high investment cost as a test facility.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem, the utility model provides a human prothrombin complex adsorption test device.
The utility model discloses a following technical scheme can realize:
the utility model provides a human prothrombin complex adsorption test device, includes a jar body and aeration component, the dog-house has been seted up at the top of jar body, is equipped with sealed lid in the dog-house department of throwing on the jar body, the internal filter sieve that is equipped with of jar, the top of the internal filter sieve of jar is equipped with reagent and puts in the subassembly, be equipped with flowing back subassembly in the below of filter sieve on the jar body, the aeration subassembly is located outside the jar body to be connected with the bottom of the jar body.
The diameter of the upper part of the tank body is larger than that of the lower part, and the middle part of the tank body is transited through an inclined plane.
The lower part of the tank body is of a double-layer structure, the closed space between the inner layer and the outer layer is a temperature control cavity, the lower part of the temperature control cavity is provided with a liquid inlet pipe, and the upper part of the temperature control cavity is provided with a return pipe.
The reagent feeding assembly comprises a pipeline, the upper end of the pipeline is connected with the top of the tank body and communicated with the outside, and the lower end of the pipeline extends to the lower part of the tank body.
The upper end of the pipeline is connected with a funnel, and the inner side of the funnel is provided with a sealing plug.
The liquid discharge assembly comprises a liquid discharge pipe and a ball valve installed on the liquid discharge pipe.
The aeration component comprises an air pump, the air pump is connected with the bottom of the tank body through a hose, and a one-way valve is installed at one end, close to the tank body, of the hose.
And a safety valve is arranged at the top of the tank body.
A plurality of supporting legs are fixedly arranged at the bottom of the tank body.
The beneficial effects of the utility model reside in that: the testing device has the advantages of simple structure and low manufacturing cost. Compressed air is intermittently blown into the tank body by using an air pump, so that the aim of stirring the blood plasma and the gel is fulfilled. Because the diameter of the upper part of the tank body is larger than that of the lower part, the materials thrown into the tank body can be gathered at the bottom of the tank body, so that the mixed liquid containing PCC required by the test can be obtained by throwing a small amount of materials, and the test cost is low.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
In the figure: 1-tank body, 2-sealing cover, 3-sealing plug, 4-pipeline, 5-reflux pipe, 6-temperature control cavity, 7-liquid discharge component, 8-single valve, 9-hose, 10-air pump, 11-liquid inlet pipe and 12-filtering sieve plate.
Detailed Description
The technical solution of the present invention is further described below, but the scope of the claimed invention is not limited to the described.
As shown in figure 1, a people prothrombin complex adsorption test device, including a jar body 1 and aeration subassembly, the dog-house has been seted up at the top of jar body 1, and jar body 1 is gone up and is thrown that feed port department articulates there is sealed lid 2, install in jar body 1 and filter sieve 12, the subassembly is put in to the reagent is installed to the top of jar internal 1 filter sieve 12, the welding of jar body 1 is in the below of filtering sieve 12 has flowing back subassembly 7, the aeration subassembly is located jar body 1 outside to be connected with jar body 1's bottom.
The diameter of the upper part of the tank body 1 is larger than that of the lower part, and the middle part is transited through an inclined plane.
The lower part of the tank body 1 is of a double-layer structure, a closed space between an inner layer and an outer layer is a temperature control cavity 6, a liquid inlet pipe 11 is welded at the lower part of the temperature control cavity 6, and a return pipe 5 is welded at the upper part of the temperature control cavity 6. Hot water is introduced into the temperature control cavity 6 to heat the lower part of the tank body 1.
The reagent feeding assembly comprises a pipeline 4, the upper end of the pipeline 4 is connected with the top of the tank body 1 and communicated with the outside, and the lower end of the pipeline 4 extends to the lower part of the tank body 1. Washing liquid and eluent are conveniently put into the tank body 1 through the reagent putting component.
The upper end of the pipeline 4 is connected with a funnel, and the inner side of the funnel is provided with a sealing plug 3.
The drain assembly 7 comprises a drain pipe and a ball valve mounted on the drain pipe.
The aeration component comprises an air pump 10, the air pump 10 is connected with the bottom of the tank body 1 through a hose 9, and a one-way valve 8 is installed at one end, close to the tank body 1, of the hose 9. Compressed air is intermittently blown into the tank body 1 by an air pump 10. A single valve 8 is provided to prevent a large amount of liquid in the tank 1 from flowing into the hose 9.
And a safety valve is arranged at the top of the tank body 1. The air pressure in the tank body 1 is controlled within a safe range.
A plurality of supporting legs are welded at the bottom of the tank body 1.
Specifically, the test device is installed in a sterile workshop.
Human prothrombin complex adsorption test device, its theory of operation or use as follows:
introducing hot water into the temperature control cavity 6, opening the sealing cover 2, putting a proper amount of gel and plasma into the tank body 1, gathering the gel and the plasma at the lower part of the tank body 1, closing the sealing cover 2, starting the air pump 10, intermittently blowing compressed air into the tank body 1 by the air pump 10, vibrating or rolling the gel and the plasma, and performing the adsorption process of PCC. After the adsorption is finished, the ball valve on the liquid discharge pipe is opened, the plasma in the tank body 1 is discharged, and then the ball valve is closed. And opening the sealing plug 3, adding a washing solution into the tank body 1 through the funnel and the pipeline 4 to wash the gel, and adding an eluent into the tank body 1 through the funnel and the pipeline 4 to elute the PPC from the gel, thereby completing the adsorption separation operation of the PCC. And opening a ball valve on the drain pipe to obtain a mixed liquid containing PCC, and finally carrying out various test detections on the mixed liquid.
In conclusion, the testing device has the advantages of simple structure and low manufacturing cost. Compressed air is intermittently blown into the tank body 1 by using an air pump 10, so that the aim of stirring the blood plasma and the gel is fulfilled. As the diameter of the upper part of the tank body 1 is larger than that of the lower part, the materials thrown into the tank body 1 can be gathered at the bottom of the tank body 1, so that the mixed liquid containing PCC required by the test can be obtained by throwing a small amount of materials, and the test cost is low.
Claims (9)
1. A human prothrombin complex adsorption test device is characterized in that: including a jar body (1) and aeration subassembly, the dog-house has been seted up at the top of the jar body (1), is equipped with sealed lid (2) in the dog-house department on the jar body (1), be equipped with in the jar body (1) and filter sieve (12), the top of the inherent filter sieve (12) of the jar body (1) is equipped with reagent and puts in the subassembly, be equipped with flowing back subassembly (7) in the below of filtering sieve (12) on the jar body (1), the aeration subassembly is located outside the jar body (1) to be connected with the bottom of the jar body (1).
2. The human prothrombin complex adsorption test device of claim 1, wherein: the diameter of the upper part of the tank body (1) is larger than that of the lower part, and the middle part of the tank body is transited through an inclined plane.
3. The human prothrombin complex adsorption test device of claim 2, wherein: the lower part of the tank body (1) is of a double-layer structure, the closed space between the inner layer and the outer layer is a temperature control cavity (6), the lower part of the temperature control cavity (6) is provided with a liquid inlet pipe (11), and the upper part of the temperature control cavity (6) is provided with a return pipe (5).
4. The human prothrombin complex adsorption test device of claim 1, wherein: the reagent feeding assembly comprises a pipeline (4), the upper end of the pipeline (4) is connected with the top of the tank body (1) and is communicated with the outside, and the lower end of the pipeline (4) extends to the lower part of the tank body (1).
5. The human prothrombin complex adsorption test device of claim 4, wherein: the upper end of the pipeline (4) is connected with a funnel, and the inner side of the funnel is provided with a sealing plug (3).
6. The human prothrombin complex adsorption test device of claim 1, wherein: the liquid discharge assembly (7) comprises a liquid discharge pipe and a ball valve arranged on the liquid discharge pipe.
7. The human prothrombin complex adsorption test device of claim 1, wherein: the aeration component comprises an air pump (10), the air pump (10) is connected with the bottom of the tank body (1) through a hose (9), and a one-way valve (8) is installed at one end, close to the tank body (1), of the hose (9).
8. The human prothrombin complex adsorption test device of claim 7, wherein: the top of the tank body (1) is provided with a safety valve.
9. The human prothrombin complex adsorption test device of claim 1, wherein: a plurality of supporting legs are fixedly arranged at the bottom of the tank body (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021492148.9U CN212833762U (en) | 2020-07-24 | 2020-07-24 | Human prothrombin complex adsorption test device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021492148.9U CN212833762U (en) | 2020-07-24 | 2020-07-24 | Human prothrombin complex adsorption test device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212833762U true CN212833762U (en) | 2021-03-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021492148.9U Active CN212833762U (en) | 2020-07-24 | 2020-07-24 | Human prothrombin complex adsorption test device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212833762U (en) |
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2020
- 2020-07-24 CN CN202021492148.9U patent/CN212833762U/en active Active
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