CN111773120A - Compound washing and protecting preparation for removing parasites of animals and preparation method thereof - Google Patents

Compound washing and protecting preparation for removing parasites of animals and preparation method thereof Download PDF

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CN111773120A
CN111773120A CN202010805953.0A CN202010805953A CN111773120A CN 111773120 A CN111773120 A CN 111773120A CN 202010805953 A CN202010805953 A CN 202010805953A CN 111773120 A CN111773120 A CN 111773120A
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parts
additive
preparation
animals
essential oil
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刘学军
万炜
苏天健
侯哲
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Anhui Ozonfun Biotechnology Co ltd
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Anhui Ozonfun Biotechnology Co ltd
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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    • A61Q17/02Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

The invention discloses a compound washing and caring preparation for removing parasites of animals and a preparation method thereof, relating to the field of compound washing and caring preparations; in order to better sterilize and prevent mosquitoes; the compound preparation comprises the following components in parts by weight: 0.5-1.5 parts of sodium percarbonate, 1.5-3 parts of an anionic surfactant, 1.5-3 parts of an amphoteric surfactant, 3-5 parts of an emulsifier, 35-50 parts of a natural source mite killing agent, 5-12 parts of an antifungal agent, 1-1.5 parts of sodium xylene sulfonate, 10-15 parts of an additive A, 3-6 parts of an additive B and 70-100 parts of deionized water; the additive B comprises: 1.5-3 parts of tea tree essential oil, 0.5-1.5 parts of vitamin B and 1-1.5 parts of shaddock peel essential oil. The washing and protecting compound preparation prepared by the invention not only has the effect of killing parasites, but also can continuously prevent mosquito bites, and has good treatment effect on superficial fungal infection and deep fungal infection on the body surface of animals.

Description

Compound washing and protecting preparation for removing parasites of animals and preparation method thereof
Technical Field
The invention relates to the technical field of washing and caring compound preparations, in particular to a washing and caring compound preparation for removing parasites of animals and a preparation method thereof.
Background
In the process of animal breeding, both the pet and the livestock are kept, particularly in hot summer, a plurality of parasites exist on the body surface of the livestock to a greater or lesser extent, so that the physiological activities of the animals are affected when the parasites are infected, and the disease deterioration and propagation can be caused when the parasites are serious; people often adopt the deinsectization washing and protecting preparation to clean parasites on the body surface of animals, and some washing and protecting preparations have the effect of killing the parasites but can not continuously prevent the mosquitoes from biting; the animals were still infested.
Upon search, chinese patent application No. CN201280064657.3 discloses a composition containing low concentrations of benzyl alcohol, one or more essential oils, and one or more plant extracts that are effective against microorganisms. The compositions of the present invention are useful in personal care products including wound care products and veterinary products. In certain embodiments, the compositions have antimicrobial actives that are mostly or substantially entirely derived from natural resources, thus avoiding the use of harsh and/or toxic chemicals by the user. This is particularly beneficial for use by children or pets, or in the home or other environment where children or pets are present, the compositions of the above patents, while having parasiticidal efficacy, do not provide a sustained protection against mosquito bites; the animals were still infested.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a compound preparation for removing parasites of animals and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a compound preparation for removing parasites of animals comprises the following components in parts by weight: 0.5-1.5 parts of sodium percarbonate, 1.5-3 parts of an anionic surfactant, 1.5-3 parts of an amphoteric surfactant, 3-5 parts of an emulsifier, 35-50 parts of a natural source mite killing agent, 5-12 parts of an antifungal agent, 1-1.5 parts of sodium xylene sulfonate, 10-15 parts of an additive A, 3-6 parts of an additive B and 70-100 parts of deionized water; the additive B comprises: 1.5-3 parts of tea tree essential oil, 0.5-1.5 parts of vitamin B and 1-1.5 parts of shaddock peel essential oil.
Preferably: the anionic surfactant is sodium dodecyl sulfate; the amphoteric surfactant is dodecyl amino propionic acid, and the emulsifier is lecithin; the natural source mite killing agent comprises: 20-30 parts of rush, 15-20 parts of rosemary; the antifungal agent comprises: 3.5-8 parts of ketoconazole and 1.5-4 parts of itraconazole; the additive A comprises: 8-11 parts of calamine micro powder and 2-4 parts of glycerol.
Preferably: the compound preparation comprises the following components in parts by weight: 1 part of sodium percarbonate, 2 parts of anionic surfactant, 2 parts of amphoteric surfactant, 3 parts of emulsifier, 40 parts of natural-source acaricide, 7 parts of antifungal agent, 1 part of sodium xylene sulfonate, an additive A11 part, an additive B4 part and 80 parts of deionized water.
Preferably: the natural source mite killing agent comprises: 25 parts of rush grass and 15 parts of rosemary; the antifungal agent comprises: 5 parts of ketoconazole and 2 parts of itraconazole; the additive A comprises: 9 parts of calamine micro powder and 2 parts of glycerol; the additive B comprises: 2 parts of tea tree essential oil, 1 parts of vitamin B and 1 part of shaddock peel essential oil.
A method for preparing a compound preparation for removing parasites of animals by washing comprises the following steps:
s1: weighing the raw materials according to the weight for later use;
s2: crushing rush mat and rosemary by a crusher, squeezing, and filtering the produced juice to prepare mixed juice for later use;
s3: putting deionized water into a stirrer, adding the antifungal agent and the additive A, stirring and mixing for 10-15 min at 50-70 ℃, and controlling the rotating speed at 600-800 r/min; uniformly adding sodium xylene sulfonate, an anionic surfactant and an amphoteric surfactant during the process;
s4: adding the mixed juice prepared in the step S2 and an emulsifier, continuously stirring for 10-15 min, and slowly cooling to 30-40 ℃ in the period;
s5: adding the additive B, increasing the rotating speed to 1000-1200 r/min, stirring for 10-15 min, cooling, and filling into bottles;
s6: and sealing sodium percarbonate by adopting a plastic film, placing the sodium percarbonate at the bottom of a bottle opening, and packaging the bottle opening and the bottle body after packaging.
Preferably: after the packaging in the step S6, tearing the sodium percarbonate film when in use, pouring the sodium percarbonate film into the solution in the bottle, and shaking up to obtain a compound preparation; in the step S3, the preparation process specifically comprises: putting deionized water into a stirrer, adding the antifungal agent and the additive A, stirring and mixing for 10min at the temperature of 52-55 ℃, and controlling the rotating speed at 700/min; during the period, sodium percarbonate, sodium xylene sulfonate, anionic surfactant and amphoteric surfactant are added homogeneously.
Preferably: in the step S4, the preparation process specifically comprises: adding the mixed juice prepared in the step S2 and an emulsifier, continuously stirring for 10min, and slowly cooling to 30-33 ℃ in the period.
Preferably: in the step S5, the preparation process specifically comprises: adding additive B, increasing rotation speed to 1000r/min, stirring for 10min, and cooling to obtain compound preparation.
Preferably: in the step S3, when the additive a is added, rhizoma atractylodis micropowder and rhubarb powder are additionally added, wherein the calamine micropowder: rhizoma atractylodis micropowder: the adding proportion of the rhubarb powder is as follows: 4:2: 1; in the step S5, adding the additive B and simultaneously adding lemon essential oil, wherein the tea tree essential oil: the addition proportion of the lemon essential oil is as follows: 3:2.
The invention has the beneficial effects that:
1. the compound washing and protecting preparation prepared by the invention not only has the effect of killing parasites, but also can continuously prevent mosquito bites, and has good treatment effect on superficial fungal infection and deep fungal infection on the body surface of animals; in addition, the product can also repair animal skin, and has strong mite preventing and removing effects.
2. The mixed juice prepared from the rush and the rosemary is added, so that the mites can be effectively removed, and the natural mite removing raw materials are adopted, so that the irritation can be avoided, and the animal skin can be better protected.
3. By adding the tea tree essential oil, the vitamin B and the shaddock peel essential oil, a good mosquito repelling effect can be provided, mosquito bites are avoided, and the animal infection probability is reduced; and due to the addition of the lemon essential oil, the effect of harmonizing smell is achieved while the secretion of body surface grease can be balanced.
4. According to the invention, by adding the calamine micro powder, the rhizoma atractylodis micro powder and the rhubarb powder, the treatment and repair effects on the skin are further improved, the skin-care liquid has the advantages of being mild and non-irritating, and can achieve the effect of relieving itching.
Drawings
FIG. 1 is a flow chart of a preparation method of a compound preparation for removing parasites of animals.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Example 1:
a compound preparation for removing parasites of animals comprises the following components in parts by weight: 0.5-1.5 parts of sodium percarbonate, 1.5-3 parts of an anionic surfactant, 1.5-3 parts of an amphoteric surfactant, 3-5 parts of an emulsifier, 35-50 parts of a natural source mite killing agent, 5-12 parts of an antifungal agent, 1-1.5 parts of sodium xylene sulfonate, 10-15 parts of an additive A, 3-6 parts of an additive B and 70-100 parts of deionized water; the additive B comprises: 1.5-3 parts of tea tree essential oil, 0.5-1.5 parts of vitamin B and 1-1.5 parts of shaddock peel essential oil.
The anionic surfactant is specifically sodium dodecyl sulfate or sodium hexadecyl sulfate, and preferably sodium dodecyl sulfate; the amphoteric surfactant is dodecyl amino propionic acid, and the emulsifier is lecithin.
The natural source mite killing agent comprises: 20-30 parts of rush, 15-20 parts of rosemary; the antifungal agent comprises: 3.5-8 parts of ketoconazole and 1.5-4 parts of itraconazole; the additive A comprises: 8-11 parts of calamine micro powder and 2-4 parts of glycerol.
The compound preparation comprises the following components in parts by weight: 1 part of sodium percarbonate, 2 parts of anionic surfactant, 2 parts of amphoteric surfactant, 3 parts of emulsifier, 40 parts of natural-source acaricide, 7 parts of antifungal agent, 1 part of sodium xylene sulfonate, an additive A11 part, an additive B4 part and 80 parts of deionized water.
The natural source mite killing agent comprises: 25 parts of rush grass and 15 parts of rosemary; the antifungal agent comprises: 5 parts of ketoconazole and 2 parts of itraconazole; the additive A comprises: 9 parts of calamine micro powder and 2 parts of glycerol; the additive B comprises: 2 parts of tea tree essential oil, 1 parts of vitamin B and 1 part of shaddock peel essential oil.
Example 2:
a preparation method of a compound preparation for removing parasites of animals comprises the following steps in sequence:
s1: weighing the raw materials according to the weight for later use;
s2: crushing rush mat and rosemary by a crusher, squeezing, and filtering the produced juice to prepare mixed juice for later use;
s3: putting deionized water into a stirrer, adding the antifungal agent and the additive A, stirring and mixing for 10-15 min at 50-70 ℃, and controlling the rotating speed at 600-800 r/min; uniformly adding sodium xylene sulfonate, an anionic surfactant and an amphoteric surfactant during the process;
s4: adding the mixed juice prepared in the step S2 and an emulsifier, continuously stirring for 10-15 min, and slowly cooling to 30-40 ℃ in the period;
s5: adding the additive B, increasing the rotating speed to 1000-1200 r/min, stirring for 10-15 min, cooling, and filling into bottles;
s6: and sealing sodium percarbonate by adopting a plastic film, placing the sodium percarbonate at the bottom of a bottle opening, and packaging the bottle opening and the bottle body after packaging.
And (4) after the packaging in the step S6, tearing off the sodium percarbonate film when in use, pouring the sodium percarbonate film into the solution in the bottle, and shaking up to obtain the compound preparation.
In the step S3, the preparation process specifically comprises: putting deionized water into a stirrer, adding the antifungal agent and the additive A, stirring and mixing for 10min at the temperature of 52-55 ℃, and controlling the rotating speed at 700/min; during the period, sodium percarbonate, sodium xylene sulfonate, anionic surfactant and amphoteric surfactant are added homogeneously.
In the step S4, the preparation process specifically comprises: adding the mixed juice prepared in the step S2 and an emulsifier, continuously stirring for 10min, and slowly cooling to 30-33 ℃ in the period.
In the step S5, the preparation process specifically comprises: adding additive B, increasing rotation speed to 1000r/min, stirring for 10min, and cooling to obtain compound preparation.
In the step S3, when the additive a is added, rhizoma atractylodis micropowder and rhubarb powder are additionally added, wherein the calamine micropowder: rhizoma atractylodis micropowder: the adding proportion of the rhubarb powder is as follows: 4:2: 1; in the step S5, adding the additive B and simultaneously adding lemon essential oil, wherein the tea tree essential oil: the addition proportion of the lemon essential oil is as follows: 3:2.
The following is a part of treatment case data to prove the efficacy of the compound preparation for removing parasites.
Example 1: a pet dog; before using the compound preparation, the dog suffers from the fungal dermatosis; after the compound preparation is used for 1 week, the disease is obviously improved, and the disease is completely cured after the compound preparation is continuously used for 1 month.
Example 2: a pet cat; before using the compound preparation, the patient suffers from eczema; after 1 month of using the compound preparation, all symptoms completely disappeared.
Example 3: cattle; before using the compound preparation, the dermatitis is serious; after 2 months of use of the compound preparation, all symptoms completely disappeared.
Example 4: a pet cat; before the compound preparation is used, a plurality of black secretions are found in ears, and earmites are found; after 1 week of use of the combination, all symptoms completely disappeared.
Example 5: a pet dog; before using the compound preparation, the body surface suffers from folliculitis; after 1 week of use of the combination, all symptoms completely disappeared.
Example 6: a pet cat; infection of microsporidia canis before use of the combination; after 1 month of using the compound preparation, all symptoms completely disappeared.
Example 7: a pet cat; before using the compound preparation, trichophyton is infected; after 2 weeks of use of the combination, all symptoms completely disappeared.
Example 8: a pig; before using the compound preparation, the exudative dermatitis is serious; after the compound preparation is used for 1 month, the disease is obviously improved, and the disease is completely cured after the compound preparation is continuously used for 1 month.
Example 9: a pig; before using the compound preparation, the body surface suffers from the swine pox; after 1 month of using the compound preparation, all symptoms completely disappeared.
Example 10: a pet cat; before using the compound preparation, the gypsum-like microsporidian is infected; after 1 week of use of the combination, all symptoms completely disappeared.
The cure rate statistics are as follows:
time of treatment Cure rate
0 to 1 week 64%
0 to 1 month 87%
0 to 3 months 100%
Within 0-1 week of using the compound preparation, most of the skin diseases of the animals can be cured, a small number of the animals have obvious treatment effect, the symptoms are obviously relieved, and within 3 months of using the compound preparation, the skin diseases of the animals can be completely cured.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (9)

1. The compound preparation for removing parasites of animals is characterized by comprising the following components in parts by weight: 0.5-1.5 parts of sodium percarbonate, 1.5-3 parts of an anionic surfactant, 1.5-3 parts of an amphoteric surfactant, 3-5 parts of an emulsifier, 35-50 parts of a natural source mite killing agent, 5-12 parts of an antifungal agent, 1-1.5 parts of sodium xylene sulfonate, 10-15 parts of an additive A, 3-6 parts of an additive B and 70-100 parts of deionized water; the additive B comprises: 1.5-3 parts of tea tree essential oil, 0.5-1.5 parts of vitamin B and 1-1.5 parts of shaddock peel essential oil.
2. The compound formulation for removing parasites on animals according to claim 1, wherein the anionic surfactant is sodium lauryl sulfate; the amphoteric surfactant is dodecyl amino propionic acid, and the emulsifier is lecithin; the natural source mite killing agent comprises: 20-30 parts of rush, 15-20 parts of rosemary; the antifungal agent comprises: 3.5-8 parts of ketoconazole and 1.5-4 parts of itraconazole; the additive A comprises: 8-11 parts of calamine micro powder and 2-4 parts of glycerol.
3. The compound preparation for removing parasites of animals according to claim 2, which comprises the following components in parts by weight: 1 part of sodium percarbonate, 2 parts of anionic surfactant, 2 parts of amphoteric surfactant, 3 parts of emulsifier, 40 parts of natural-source acaricide, 7 parts of antifungal agent, 1 part of sodium xylene sulfonate, an additive A11 part, an additive B4 part and 80 parts of deionized water.
4. The compound preparation for removing parasites and washing and protecting animals as claimed in claim 3, wherein the natural mite-killing agent comprises: 25 parts of rush grass and 15 parts of rosemary; the antifungal agent comprises: 5 parts of ketoconazole and 2 parts of itraconazole; the additive A comprises: 9 parts of calamine micro powder and 2 parts of glycerol; the additive B comprises: 2 parts of tea tree essential oil, 1 parts of vitamin B and 1 part of shaddock peel essential oil.
5. A preparation method of a compound preparation for removing parasites of animals is characterized by comprising the following steps:
s1: weighing the raw materials according to the weight for later use;
s2: crushing rush mat and rosemary by a crusher, squeezing, and filtering the produced juice to prepare mixed juice for later use;
s3: putting deionized water into a stirrer, adding the antifungal agent and the additive A, stirring and mixing for 10-15 min at 50-70 ℃, and controlling the rotating speed at 600-800 r/min; uniformly adding sodium xylene sulfonate, an anionic surfactant and an amphoteric surfactant during the process;
s4: adding the mixed juice prepared in the step S2 and an emulsifier, continuously stirring for 10-15 min, and slowly cooling to 30-40 ℃ in the period;
s5: adding the additive B, increasing the rotating speed to 1000-1200 r/min, stirring for 10-15 min, cooling, and filling into bottles;
s6: and sealing sodium percarbonate by adopting a plastic film, placing the sodium percarbonate at the bottom of a bottle opening, and packaging the bottle opening and the bottle body after packaging.
6. The method for preparing a compound preparation for removing parasites from animals according to claim 5, wherein after the step S6, the sodium percarbonate film is torn off and poured into the solution in the bottle for uniform shaking to obtain the compound preparation; in the step S3, the preparation process specifically comprises: putting deionized water into a stirrer, adding the antifungal agent and the additive A, stirring and mixing for 10min at the temperature of 52-55 ℃, and controlling the rotating speed at 700/min; during the period, sodium percarbonate, sodium xylene sulfonate, anionic surfactant and amphoteric surfactant are added homogeneously.
7. The preparation method of the compound preparation for removing parasites on animals according to claim 5, wherein in the step S4, the preparation process comprises the following steps: adding the mixed juice prepared in the step S2 and an emulsifier, continuously stirring for 10min, and slowly cooling to 30-33 ℃ in the period.
8. The preparation method of the compound preparation for removing parasites on animals according to claim 5, wherein in the step S5, the preparation process comprises the following steps: adding additive B, increasing rotation speed to 1000r/min, stirring for 10min, and cooling to obtain compound preparation.
9. The method for preparing a compound animal parasite removal washing and caring preparation according to any one of claims 5-8, wherein in the step of S3, when additive A is added, rhizoma Atractylodis micropowder and radix et rhizoma Rhei powder are additionally added, the calamine micropowder: rhizoma atractylodis micropowder: the adding proportion of the rhubarb powder is as follows: 4:2: 1; in the step S5, adding the additive B and simultaneously adding lemon essential oil, wherein the tea tree essential oil: the addition proportion of the lemon essential oil is as follows: 3:2.
CN202010805953.0A 2020-08-12 2020-08-12 Compound washing and protecting preparation for removing parasites of animals and preparation method thereof Pending CN111773120A (en)

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