CN111759502A - Preparation device and method of hydrophilic implant - Google Patents
Preparation device and method of hydrophilic implant Download PDFInfo
- Publication number
- CN111759502A CN111759502A CN202010726670.7A CN202010726670A CN111759502A CN 111759502 A CN111759502 A CN 111759502A CN 202010726670 A CN202010726670 A CN 202010726670A CN 111759502 A CN111759502 A CN 111759502A
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- Prior art keywords
- implant
- inert gas
- dental implant
- gas protection
- protection frame
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/06—Titanium or titanium alloys
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23F—NON-MECHANICAL REMOVAL OF METALLIC MATERIAL FROM SURFACE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL; MULTI-STEP PROCESSES FOR SURFACE TREATMENT OF METALLIC MATERIAL INVOLVING AT LEAST ONE PROCESS PROVIDED FOR IN CLASS C23 AND AT LEAST ONE PROCESS COVERED BY SUBCLASS C21D OR C22F OR CLASS C25
- C23F1/00—Etching metallic material by chemical means
- C23F1/08—Apparatus, e.g. for photomechanical printing surfaces
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23F—NON-MECHANICAL REMOVAL OF METALLIC MATERIAL FROM SURFACE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL; MULTI-STEP PROCESSES FOR SURFACE TREATMENT OF METALLIC MATERIAL INVOLVING AT LEAST ONE PROCESS PROVIDED FOR IN CLASS C23 AND AT LEAST ONE PROCESS COVERED BY SUBCLASS C21D OR C22F OR CLASS C25
- C23F1/00—Etching metallic material by chemical means
- C23F1/10—Etching compositions
- C23F1/14—Aqueous compositions
- C23F1/16—Acidic compositions
- C23F1/26—Acidic compositions for etching refractory metals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
Abstract
The invention discloses a preparation device and a preparation method of a hydrophilic implant, which comprises a nitrogen or inert gas protection device under an acid etching process, a cleaning process and an inner packaging process, wherein the device comprises an inert gas protection frame, a container groove and an implant fixing support, the inert gas protection frame is internally filled with nitrogen or inert gas for protection, so that the pollution of the dental implant in the air is avoided, a packaging bottle for the dental implant is designed in the inner packaging process, the packaging bottle comprises a bottle body, a bottle cap and an implant placing frame, and physiological tissue liquid is injected into the bottle body for isolating the air and avoiding the surface pollution of the dental implant. The invention protects the links of pollution turnover, storage and the like in the whole production link of the dental implant, avoids the pollution of C element on the surface of the implant, keeps the hydrophilic high surface energy of the implant, and increases the protein adsorption capacity and the cell adhesion, proliferation and differentiation capacity.
Description
Technical Field
The invention relates to the technical field of oral implantation, in particular to a device and a method for preparing a hydrophilic implant.
Background
The surface characteristics of the endosteal implant materials such as dental implants, such as surface morphology, hydrophilicity, and the like, are key factors influencing the osseointegration and clinical efficacy of the implants. In the existing surface treatment technology, the sand blasting and acid etching treatment technology has ideal effect. However, the surfaces of pure titanium and titanium alloy treated by sand blasting and acid etching have strong hydrophobicity, which greatly hinders the interaction between cells and materials and delays early osseointegration. The process of implanting the implant and combining the bone is actually the process of combining the biological tissue and the chemical bond of the bioactive material, and as the main factors influencing the speed and the strength of the bone combination, the biological activity of the implant surface is high or low, the physical and chemical properties are important, and the physical and chemical properties and the biological activity of the pure titanium surface are also closely related.
Titanium and titanium alloy metal are biological inert materials, and have a large difference with bone tissue in terms of properties, and once a passive oxide film is formed on the surface of pure titanium, the chemical bonding with the bone tissue is more difficult. Therefore, the clinical application usually adopts the surface activation method to achieve the purpose of direct bonding between the implant and the biological tissue. Experiments show that after sand blasting and acid etching, in the test of the ion component attached to the surface of the implant, cation Ti and anion O which are beneficial to bone union acceleration are mainly used, and at the moment, the implant has higher surface energy and is beneficial to bone union. The method has timeliness no matter what the method for biological activation treatment of the pure titanium surface. After the dental implant is preserved for a period of time, the high surface energy and the high bioactivity effect obtained by treating the surface of the pure titanium gradually disappear, and the bioactivity obviously reduces along with the prolonging of the preservation time, namely the aging of the bioactivity of the surface of the titanium.
Disclosure of Invention
The invention aims to provide a device and a method for preparing a hydrophilic implant, which can prevent the pollution of C element on the surface of the implant, keep the hydrophilic high surface energy of the implant and increase the protein adsorption capacity and the cell adhesion, proliferation and differentiation capacity by protecting the links of pollution turnover, storage and the like in the whole production link of the dental implant so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a preparation device of a hydrophilic implant comprises an inert gas protection frame, a container groove and a telescopic shaft; the inert gas protection frame is provided with an injection port, and is externally connected with an inert gas injection pipeline through the injection port; the telescopic shaft penetrates through the center of the inert gas protection frame and is in threaded connection with the inert gas protection frame; the lower end of the telescopic shaft is connected with an implant fixing support, the implant fixing support is arranged in the inert gas protection frame, and a dental implant is placed on the lower end face of the implant fixing support.
Furthermore, the dental implant packaging bottle also comprises a packaging bottle for placing the dental implant, the packaging bottle consists of a bottle body and a bottle cap, and the bottom of the bottle body is provided with an implant placing rack; the dental implant is sleeved on the implant placing frame.
Furthermore, the cavity of the bottle body is filled with physiological tissue fluid, and the physiological tissue fluid wraps the dental implant.
Further, the physiological tissue fluid is a HANKS balanced salt solution.
Further, the packaging bottle containing the dental implant is placed in a blister pack, which is heat sealed with the dialysis paper.
Furthermore, the space above the liquid level in the container tank is isolated from the inert gas protection frame through nitrogen or inert gas injected through an inert gas injection pipeline.
The invention provides another technical scheme: a method of making a device for hydrophilic implants, comprising the steps of:
s1: carrying out sand blasting treatment on the dental implant, and then carrying out cleaning treatment;
s2: assembling the whole inert gas protection frame, assembling the dental implant on the implant fixing bracket, and continuously injecting nitrogen or inert gas into an inert gas injection pipeline connected with the inert gas protection frame for 1 minute;
s3: acid etching process: integrally moving the inert gas protection frame to the upper part of the container tank, filling the acidic corrosive liquid into the container tank, and then moving the implant fixing bracket downwards to ensure that the dental implant is completely immersed in the acidic corrosive liquid and is subjected to acid etching for a certain time;
s4: a first cleaning procedure: integrally moving the inert gas protection frame to the upper part of the other container tank, filling purified water in the container tank, then moving the implant fixing bracket downwards to ensure that the dental implant is completely immersed in the purified water, and ultrasonically cleaning for 12 minutes;
s5: moving the inert gas protection frame out of a certain space from the upper part of the container groove, taking down the dental implant below the implant fixing bracket, putting the dental implant into a bottle body containing physiological tissue fluid, covering a bottle cap, and finishing assembly to ensure that no fluid seeps out of a packaging bottle;
s6: putting the packaging bottle into a plastic uptake box, and performing heat sealing by using dialyzing paper;
s7: packaging, and sterilizing.
Further, the continuous injection of nitrogen or inert gas through the inert gas injection pipe in S5 ensures full gas protection.
Compared with the prior art, the invention has the beneficial effects that:
according to the device and the method for preparing the hydrophilic implant, provided by the invention, the C element pollution caused by exposure to air in the production process is effectively isolated through the acid etching process of the dental implant and the protection of nitrogen or inert gas in the cleaning process, and the inner packaging process is adopted, so that the dental implant is stored in physiological tissue liquid, and the pollution effect is also achieved.
Drawings
FIG. 1 is an overall block diagram of the present invention;
FIG. 2 is a state diagram of the present invention in use of FIG. 1;
FIG. 3 is a cross-sectional view of the package bottle of the present invention;
fig. 4 is a state view of the outsourcing of the packing bottle of the present invention.
In the figure: 1. an inert gas protection frame; 2. a container tank; 3. a telescopic shaft; 4. an inert gas injection line; 5. an implant fixing bracket; 6. a dental implant; 11. packaging bottles; 12. a bottle body; 13. a bottle cap; 14. placing the implant; 15. a plastic sucking box; 16. dialyzing paper; 17. a physiological tissue fluid.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, in the embodiment of the present invention: provides a preparation device of a hydrophilic implant, which comprises an inert gas protection frame 1, a container groove 2 and a telescopic shaft 3; an injection port is arranged on the inert gas protection frame 1, and an inert gas injection pipeline 4 is externally connected through the injection port; the telescopic shaft 3 penetrates through the center of the inert gas protection frame 1 and is in threaded connection with the inert gas protection frame 1; the lower end of the telescopic shaft 3 is connected with an implant fixing bracket 5, the implant fixing bracket 5 is arranged inside the inert gas protection frame 1, and a dental implant 6 is placed on the lower end face of the implant fixing bracket 5.
Referring to fig. 2, in the above embodiment, the space above the liquid level in the vessel tank 2 is isolated from the inert gas protection frame 1 by the nitrogen gas or the inert gas injected through the inert gas injection pipe 4.
Referring to fig. 3, the dental implant packaging bottle further comprises a packaging bottle 11 for placing the dental implant 6, the packaging bottle 11 is composed of a bottle body 12 and a bottle cap 13, and an implant placing frame 14 is arranged at the bottom of the bottle body 12; the dental implant 6 is sleeved on the implant placing frame 14; the cavity of the bottle body 12 is filled with physiological tissue fluid 17, the dental implant 6 is wrapped by the physiological tissue fluid 17, and the physiological tissue fluid 17 is a HANKS balanced salt solution.
Referring to fig. 4, the packaging bottle 11 with the dental implant 6 is placed in a blister pack 15, and the blister pack 15 heat-seals the packaging bottle 11 through the dialysis paper 16.
The invention provides another technical scheme: a method of making a device for hydrophilic implants, comprising the steps of:
the first step is as follows: carrying out sand blasting treatment on the dental implant 6, and then carrying out cleaning treatment;
the second step is that: assembling the whole inert gas protection frame 1, assembling the dental implant 6 on the implant fixing bracket 5, and continuously injecting nitrogen or inert gas into the inert gas injection pipeline 4 connected with the inert gas protection frame 1 for 1 minute;
the third step: acid etching process: integrally moving the inert gas protection frame 1 to the upper part of the container groove 2, filling the acidic corrosive liquid into the container groove 2, and then moving the implant fixing bracket 5 downwards to ensure that the dental implant 6 is completely immersed in the acidic corrosive liquid and is subjected to acid etching for a certain time;
the fourth step: a first cleaning procedure: integrally moving the inert gas protection frame 1 to the upper part of the other container tank 2, filling purified water in the container tank 2, then moving the implant fixing bracket 5 downwards to ensure that the dental implant 6 is completely immersed in the purified water, and ultrasonically cleaning for 12 minutes;
the fifth step: moving the inert gas protection frame 1 out of a certain space from the upper part of the container groove 2, taking down the dental implant 6 below the implant fixing bracket 5, putting the dental implant into a bottle body 12 containing physiological tissue fluid 17, and covering a bottle cap 13 to finish assembly so as to ensure that no fluid seeps out of a packaging bottle 11;
and a sixth step: placing the packaging bottle 11 into a plastic uptake box 15, and performing heat sealing by using dialyzing paper 16;
the seventh step: packaging, and sterilizing.
In the above embodiment, the nitrogen gas or the inert gas is continuously injected through the inert gas injection pipe 4 in the fifth step to ensure the full-scale gas protection.
From the above, it can be seen that: in order to maintain the hydrophilic characteristic of the dental implant 6, the invention is a link influencing the hydrophilicity of the dental implant 6 in the whole production process, namely a process after the dental implant 6 is subjected to sand blasting and acid etching to avoid contacting with air, and the invention is mainly controlled by the following three links:
1. transfer control after the sand blasting process: the main processes after sand blasting include acid etching, cleaning and packing, and the whole process is carried out in nitrogen (N)2) Or under the protection of inert gas, and avoids the contact with air.
2. And in the inner packaging process, under the protection of nitrogen or inert gas, the dental implant 6 is directly packaged into a packaging bottle with physiological tissue fluid 17, and the main component of the physiological tissue fluid 17 is HANKS balanced salt solution which is finally stored in the packaging bottle 11.
3. An outer packaging step of putting the packaging bottle 11 containing the dental implant 6 into a blister pack 15, and heat-sealing the dialyzing paper 16 to the blister pack 15, followed by sterilization treatment.
In summary, the following steps: the invention provides a preparation device and a preparation method of a hydrophilic implant, wherein a nitrogen or inert gas protection device under an acid etching process, a cleaning process and an inner packaging process is innovatively designed, the device comprises three parts, namely an inert gas protection frame 1, a container groove 2 and an implant fixing support 5, nitrogen or inert gas is introduced into the inert gas protection frame 1 for protection, so that the dental implant 6 is prevented from being polluted in the air, a packaging bottle 11 for the dental implant 6 is designed in the inner packaging process, the packaging bottle 11 comprises a bottle body 12, a bottle cap 13 and an implant placing support 14, and physiological tissue liquid is injected into the bottle body 12 for isolating the air and preventing the surface of the dental implant 6 from being polluted.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be able to cover the technical solutions and the inventive concepts of the present invention within the technical scope of the present invention.
Claims (8)
1. The preparation device of the hydrophilic implant is characterized by comprising an inert gas protection frame (1), a container groove (2) and a telescopic shaft (3); an injection port is formed in the inert gas protection frame (1), and an inert gas injection pipeline (4) is externally connected through the injection port; the telescopic shaft (3) penetrates through the center of the inert gas protection frame (1) and is in threaded connection with the inert gas protection frame (1); the lower end of the telescopic shaft (3) is connected with an implant fixing support (5), the implant fixing support (5) is arranged in the inert gas protection frame (1), and a dental implant (6) is placed on the lower end face of the implant fixing support (5).
2. The device for preparing a hydrophilic implant according to claim 1, wherein: the dental implant packaging bottle also comprises a packaging bottle (11) for placing the dental implant (6), wherein the packaging bottle (11) consists of a bottle body (12) and a bottle cap (13), and an implant placing frame (14) is arranged at the bottom of the bottle body (12); the dental implant (6) is sleeved on the implant placing frame (14).
3. The device for preparing a hydrophilic implant according to claim 2, wherein: the cavity of the bottle body (12) is filled with physiological tissue liquid (17), and the physiological tissue liquid (17) wraps the dental implant (6).
4. A hydrophilic implant preparation apparatus as defined in claim 3, wherein: the physiological tissue fluid (17) is a HANKS balanced salt solution.
5. The device for preparing a hydrophilic implant according to claim 2, wherein: the packaging bottle (11) with the dental implant (6) is placed in a plastic suction box (15), and the plastic suction box (15) heat-seals the packaging bottle (11) through dialysis paper (16).
6. The device for preparing a hydrophilic implant according to claim 1, wherein: the space above the liquid level in the container tank (2) is isolated from the inert gas protection frame (1) through nitrogen or inert gas injected through an inert gas injection pipeline (4).
7. A method of preparing a device for hydrophilic implants according to claim 1, comprising the steps of:
s1: carrying out sand blasting treatment on the dental implant (6), and then carrying out cleaning treatment;
s2: assembling the whole inert gas protection frame (1), assembling the dental implant (6) on the implant fixing bracket (5), and continuously injecting nitrogen or inert gas into an inert gas injection pipeline (4) connected with the inert gas protection frame (1) for 1 minute;
s3: acid etching process: integrally moving the inert gas protection frame (1) to the upper part of the container tank (2), filling the container tank (2) with an acidic corrosive liquid, then moving the implant fixing bracket (5) downwards to ensure that the dental implant (6) is completely immersed in the acidic corrosive liquid, and carrying out acid etching for a certain time;
s4: a first cleaning procedure: integrally moving the inert gas protection frame (1) to the upper part of the other container tank (2), filling purified water in the container tank (2), then moving the implant fixing bracket (5) downwards to ensure that the dental implant (6) is completely immersed in the purified water, and ultrasonically cleaning for 12 minutes;
s5: moving the inert gas protection frame (1) out of a certain space from the upper part of the container groove (2), taking down the dental implant (6) below the implant fixing bracket (5), putting the dental implant into a bottle body (12) containing physiological tissue fluid (17), covering a bottle cap (13) to finish assembly, and ensuring that no fluid seeps out of a packaging bottle (11);
s6: putting the packaging bottle (11) into a plastic uptake box (15), and carrying out heat sealing by using dialyzing paper (16);
s7: packaging, and sterilizing.
8. The method for manufacturing a hydrophilic implant according to claim 7, wherein the continuous injection of nitrogen or inert gas through the inert gas injection tube (4) in S5 ensures full gas protection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010726670.7A CN111759502A (en) | 2020-07-25 | 2020-07-25 | Preparation device and method of hydrophilic implant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010726670.7A CN111759502A (en) | 2020-07-25 | 2020-07-25 | Preparation device and method of hydrophilic implant |
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| Publication Number | Publication Date |
|---|---|
| CN111759502A true CN111759502A (en) | 2020-10-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010726670.7A Pending CN111759502A (en) | 2020-07-25 | 2020-07-25 | Preparation device and method of hydrophilic implant |
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| CN (1) | CN111759502A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114288047A (en) * | 2021-12-30 | 2022-04-08 | 跃美生物科技(苏州)有限公司 | Surface treatment process for implant |
-
2020
- 2020-07-25 CN CN202010726670.7A patent/CN111759502A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114288047A (en) * | 2021-12-30 | 2022-04-08 | 跃美生物科技(苏州)有限公司 | Surface treatment process for implant |
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