CN111758794A - Preparation method and device of breast milk substitute fat - Google Patents
Preparation method and device of breast milk substitute fat Download PDFInfo
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- CN111758794A CN111758794A CN202010673348.2A CN202010673348A CN111758794A CN 111758794 A CN111758794 A CN 111758794A CN 202010673348 A CN202010673348 A CN 202010673348A CN 111758794 A CN111758794 A CN 111758794A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
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Abstract
The embodiment of the invention provides a preparation method and a device of breast milk substitute fat, wherein the method comprises the following steps: determining preset base oil adopted by the synthetic breast milk substitute fat; determining the proportion of each base oil by a preset mathematical model, so that the content of a preset index in the composition synthesized according to the proportion is within the content range of a corresponding index in breast milk; and (4) synthesizing the breast milk substitute fat according to the proportion of the base oil determined by the preset model. The scheme can prepare the breast milk substitute fat by an objective, scientific and comprehensive physical blending method, is accurate and efficient, and is not influenced by the base oil, so that the proportion of various preset base oil meeting the requirements can be determined, and the method has important significance for simulating breast milk fat in the prior art.
Description
Technical Field
The invention relates to the technical field of preparation of infant food, in particular to a preparation method and a device of breast milk substitute fat.
Background
The fat content of human breast milk is 3% -5%, which provides about 50% of energy for infants and young children. And more than 98% of the fat contained in breast milk is triglycerides, a fraction also commonly referred to as mother milk fat. The mother milk fat has special composition and structure, and mainly contains oleic acid, linoleic acid and palmitic acid from the view of fatty acid composition and distribution, while saturated fatty acid, especially palmitic acid, is distributed at the sn-2 position, and unsaturated fatty acid, such as oleic acid and linoleic acid, is mainly located at the sn-1 and 3 positions, and the distribution is beneficial to fat absorption of infants and young children, and promotes healthy growth of the infants and young children. From the composition of triglycerides, the triglycerides in the mother milk fat are mainly OPO and OPL, based on the composition and distribution of the fatty acids.
In recent years, along with the improvement of living standard and the development of society, the breast feeding rate of China is continuously reduced, and the research of breast milk for replacing fat is generally concerned. The chemical composition of breast milk-substituted lipids affects digestion and absorption by infants. In the case where some mothers are unable to provide feeding to infants, it is essential to prepare a milk substitute fat that is highly similar to the milk fat and add it to the infant formula.
At present, physical blending models and preparation researches of breast milk substitute lipids are few, so that an objective, scientific and comprehensive physical blending method is urgently needed to be found for preparing the breast milk substitute lipids, the components of the breast milk substitute lipids are the same as those of the breast milk lipids in breast milk, and the content of each component in the breast milk substitute lipids is in the range of the content of the corresponding component in the breast milk.
Disclosure of Invention
The invention provides a preparation method and a device of breast milk substitute fat, and aims to solve the technical problem that an objective, scientific and comprehensive physical blending method is urgently needed to prepare the breast milk substitute fat in the prior art.
In a first aspect, a method for preparing a breast milk substitute fat according to an embodiment of the present invention includes:
determining preset base oil adopted by the synthetic breast milk substitute fat;
determining the proportion of each base oil by a preset mathematical model, so that the content of a preset index in the composition synthesized according to the proportion is within the content range of a corresponding index in breast milk;
and (4) synthesizing the breast milk substitute fat according to the proportion of the base oil determined by the preset model.
In one embodiment, the preset mathematical model is:
wherein x isjThe minimum deviation value of m indexes in the mother cream is more than or equal to 0, j is 1,2, … …, n and D, and the minimum deviation value is 0; ciIs the deviation value of index i; m is the total number of selected indexes in the mother cream; n is the total amount of base oil; a. theijThe content of the index i in the jth base oil is expressed as a matrix; x is the number ofjThe percentage content of the jth base oil after blending; zu ZuiAnd ZdiThe upper limit and the lower limit of the index i in the breast milk fat are respectively.
In one embodiment, the preset indicators include total fatty acids, sn-2 fatty acids and triglycerides of the mother milk fat.
In one embodiment, the total fatty acids comprise: capric acid (Ca), lauric acid (La), myristic acid (M), palmitic acid (P), palmitoleic acid (Po), oleic acid (O), linoleic acid (L), and linolenic acid (LNA).
In one embodiment, the sn-2 fatty acid comprises lauric acid (La), myristic acid (M), palmitic acid (P), palmitoleic acid (Po), oleic acid (O), and linoleic acid (L).
In one embodiment, the triglycerides include LaLaLaO, CaPL, LLL, LaOL, CaPO, OLL, PLL, MOL, LaOL, POLa, OPL, PPL, MPO, OOO, OPO, PPO and POS.
In one embodiment, the predetermined base oil comprises soybean oil, palm oil, rapeseed oil, and coconut oil;
the proportion of each base oil determined by a preset model is soybean oil: palm oil: rapeseed oil: coconut oil 25.03%: 39.17%: 6.71%: 29.09 percent.
In one embodiment, the predetermined base oil comprises soybean oil, peanut oil, corn oil, palm oil, rapeseed oil, coconut oil, and structured fats;
the proportion of each base oil determined by a preset model is soybean oil: peanut oil: corn oil: palm oil: rapeseed oil: coconut oil: structural fat 11.44%: 2.60%: 1.71%: 0.53%: 6.12%: 14.41%: 63.20 percent.
In one embodiment, the predetermined base oil comprises peanut oil, palm oil, rapeseed oil, coconut oil, golden pompano oil, and tilapia oil;
the proportion of each base oil determined by a preset model is peanut oil: palm oil: rapeseed oil: coconut oil: golden pomfret oil: 1.3% of tilapia mossambica oil: 6.13%: 0.8%: 13.86%: 69.19%: 8.72 percent.
In a second aspect, there is provided an apparatus for preparing a human milk substitute fat according to an embodiment of the present invention, including:
the identification module is used for determining preset base oil adopted by the synthetic breast milk substitute fat;
the calculation module is used for determining the proportion of each base oil by using a preset mathematical model so that the content of a preset index in the composition synthesized according to the proportion is within the content range of a corresponding index in breast milk;
and the proportioning module is used for proportioning and synthesizing the breast milk substitute fat according to the proportion of each base material oil determined by the preset model.
In one embodiment, the preset mathematical model adopted by the calculation module is as follows:
wherein x isjThe minimum deviation value of m indexes in the mother cream is more than or equal to 0, j is 1,2, … …, n and D, and the minimum deviation value is 0; ciIs the deviation value of index i; m is the total number of selected indexes in the mother cream; n is the total amount of base oil; a. theijThe content of the index i in the jth base oil is expressed as a matrix; x is the number ofjThe percentage content of the jth base oil after blending; zu ZuiAnd ZdiThe upper limit and the lower limit of the index i in the breast milk fat are respectively.
The preparation method and the device for the breast milk substitute fat provided by the embodiment of the invention can be used for preparing the breast milk substitute fat by an objective, scientific and comprehensive physical blending method, are accurate and efficient, and are not influenced by the base oil, so that the proportion of various preset base oil meeting the requirements can be determined, and the preparation method and the device have important significance for simulating breast milk fat in the prior art.
Drawings
The accompanying drawings are provided to illustrate the present invention and it is to be understood that the following description of the preferred embodiments is illustrative of some embodiments of the invention and is not to be construed as limiting the invention. In the drawings:
FIG. 1 is a flow chart of a method for preparing a milk substitute fat according to an embodiment of the present invention;
fig. 2 is a block diagram of an apparatus for preparing breast milk substitute fat according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the specific embodiments of the present invention and the accompanying drawings. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The technical solutions provided by the embodiments of the present invention are described in detail below with reference to the accompanying drawings.
The embodiment of the invention provides a preparation method of breast milk substitute fat, which is shown in figure 1 and comprises the following steps:
step S12, determining preset base oil adopted by the synthetic breast milk substitute fat;
in the embodiment of the invention, the main purpose is to mix the preset base oil according to a certain proportion to synthesize the breast milk substitute fat, thereby providing the breast milk-like fat substitute for the infants who can not be supplied with breast milk.
Step S14, determining the proportion of each base oil by a preset mathematical model, so that the content of a preset index in the composition synthesized according to the proportion is in the same range as the content of a corresponding index in breast milk;
in the embodiment of the invention, the proportion of each base oil in the preset base oil is determined by adopting the preset mathematical model, which is different from the manual calculation in the traditional mode, and is accurate and efficient, so that the lipid substitute which meets the content of the lipid in human breast milk can be configured.
And step S16, compounding and synthesizing the breast milk substitute fat according to the proportion of the base oil determined by the preset model.
In the embodiment of the invention, after the proportion of each base oil in the preset base oil is determined through the preset mathematical model, the preset base oil is mixed according to the determined proportion to obtain the lipid compound with the lipid content in the range of the lipid content of human milk.
In the embodiment of the present invention, the preset mathematical model is:
wherein x isjThe minimum deviation value of m indexes in the mother cream is more than or equal to 0, j is 1,2, … …, n and D, and the minimum deviation value is 0; ciIs the deviation value of index i; m is the total number of selected indexes in the mother cream; n is the total amount of base oil; a. theijThe content of the index i in the jth base oil is expressed as a matrix; x is the number ofjThe percentage content of the jth base oil after blending; zu ZuiAnd ZdiThe upper limit and the lower limit of the index i in the breast milk fat are respectively.
It is noted that, depending on the specific index contained in different base oils, if the specific index represented by i is set and if one or some of the base oils does not contain the index, the content of the index i in the base oil is set to 0.
In an embodiment of the invention, the predetermined indicators comprise total fatty acids, sn-2 fatty acids and triglycerides of the mother milk fat. And the total fatty acids include: capric acid (Ca), lauric acid (La), myristic acid (M), palmitic acid (P), palmitoleic acid (Po), oleic acid (O), linoleic acid (L), and linolenic acid (LNA); the sn-2 position fatty acid includes lauric acid (La), myristic acid (M), palmitic acid (P), palmitoleic acid (Po), oleic acid (O), and linoleic acid (L). The triglyceride includes LaLaLaO (1, 2-dilaurate-3-oleate triglyceride), CaPL (1-decanoate-2-palmitate-3-linoleate triglyceride), LLL (trilinoleic acid triglyceride), LaOL (1-lauric acid-2-oleic acid-3-linoleate triglyceride), CaPO (1-capric acid-2-palmitic acid-3-oleate triglyceride), OLL (1-oleic acid-2, 3-dilinoleic acid triglyceride), PLL (1-palmitic acid-2, 3-dilinoleic acid triglyceride), MOL (1-myristic acid-2-oleic acid-3-linoleate triglyceride), LaOL (1-lauric acid-2-oleic acid-3-linoleate triglyceride), POLa (1-palmitic acid-2-oleic acid-3-lauric acid triglyceride), OPL (1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride), PPL (1, 2-dipalmitoic acid-3-linoleic acid triglyceride), MPO (1-myristic acid-2-palmitic acid-3-oleic acid triglyceride), OOO (triolein triglyceride), OPO (1, 3-dipalmitoic acid-2-oleic acid triglyceride), PPO (1, 2-dipalmitoic acid-3-oleic acid triglyceride), and POS (1-palmitic acid-2-oleic acid-3-stearic acid triglyceride).
Detailed description of the preferred embodiment 1
The selected preset base oil comprises soybean oil, palm oil, rapeseed oil and coconut oil, the types of preset indexes contained in the soybean oil, the palm oil, the rapeseed oil and the coconut oil, the indexes contained in the preset indexes and the values of the indexes are shown in table 1:
TABLE 1 Preset index contained in each base oil, index contained in the Preset index, and detailed value of each index
By using the soybean oil, the palm oil, the rapeseed oil and the coconut oil described in the table 1, the proportion of each base oil is determined to be as follows by a preset mathematical model provided by the embodiment of the invention: soybean oil: palm oil: rapeseed oil: coconut oil 25.03%: 39.17%: 6.71%: 29.09 percent. With this ratio of base oil, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk substitute fat is shown in tables 2 to 4.
Comparative examples 1 to 1
Taking soybean oil, palm oil, rapeseed oil and coconut oil as base material oil for preparing breast milk substitute fat, and blending the soybean oil in a blending ratio of: palm oil: rapeseed oil: coconut oil 15%: 29%: 17%: 39% of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substituted fat are shown in tables 1 to 3 below.
Comparative examples 1 to 2
Taking soybean oil, palm oil, rapeseed oil and coconut oil as base material oil for preparing breast milk substitute fat, and blending the soybean oil in a blending ratio of: palm oil: rapeseed oil: coconut oil 35%: 19%: 27%: 19%, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substituted lipids are shown in tables 1 to 3 below.
TABLE 2 Total fatty acid composition (%)
Total fatty acids | Detailed description of the preferred embodiment 1 | Comparative examples 1 to 1 | Comparative examples 1 to 2 | Milk fat |
C10:0 | 1.68 | 2.25 | 1.09 | 0.06~2.21 |
C12:0 | 13.63 | 18.28 | 8.90 | 1.19~8.51 |
C14:0 | 5.81 | 7.56 | 3.73 | 2.20~7.93 |
C16:0 | 24.49 | 19.93 | 16.09 | 15.07~22.62 |
C16:1 | 0.03 | 0.03 | 0.06 | 0.98~2.39 |
C18:0 | 3.61 | 3.27 | 3.23 | 3.67~8.32 |
C18:1 | 26.04 | 27.29 | 33.94 | 26.04~37.27 |
C18:2 | 20.21 | 15.76 | 26.56 | 14.19~25.52 |
C18:3 | 2.17 | 2.44 | 4.34 | 0.76~1.73 |
TABLE 3 fatty acid composition in sn-2 position (%) -of mother milk substitute fat in specific example 1 and comparative examples 1-1 and 1-2
sn-2 fatty acid | Detailed description of the preferred embodiment 1 | Comparative examples 1 to 1 | Comparative examples 1 to 2 | Milk fat |
C12:0 | 20.68 | 27.72 | 13.51 | 0.65~10.24 |
C14:0 | 3.18 | 4.19 | 2.06 | 4.46~15.52 |
C16:0 | 6.56 | 5.26 | 3.99 | 43.31~58.37 |
C16:1 | 0 | 0 | 0 | 1.37~2.74 |
C18:0 | 1.07 | 0.98 | 0.96 | 1.21~2.56 |
C18:1 | 36.43 | 34.53 | 37.06 | 6.98~17.23 |
C18:2 | 29.83 | 24.18 | 37.32 | 3.31~13.42 |
TABLE 4 triglyceride composition of mother milk substitute fat (%)
In order to clearly show the superiority of the blending ratio obtained under the preset mathematical model provided by the embodiment of the invention, the breast milk substitute lipid of the embodiment and the comparative example is scored by adopting a similarity scoring model, and the similarity scoring model is introduced from literature reports (Sunwong, composition, similarity evaluation and preparation research of human milk substitute lipid, 2018).
The similarity scores of the breast milk-substituted fat prepared by mixing vegetable fats and oils are shown in Table 5.
TABLE 5 similarity scores of breast milk substitute fat prepared in example 1, comparative examples 1-1, 1-2 and mother milk fat
Degree of similarity | Detailed description of the preferred embodiment 1 | Comparative examples 1 to 1 | Comparative examples 1 to 2 |
Total fatty acids | 78.62 | 72.15 | 76.16 |
sn-2 fatty acid | 24.98 | 29.11 | 24.24 |
Triglycerides | 67.39 | 63.63 | 60.34 |
Total score | 57.00 | 54.96 | 53.58 |
As can be seen from tables 2 to 4, the indexes of the total fatty acids, the indexes of the sn-2-position fatty acids, and the indexes of the triglycerides of the breast milk substitute fat prepared by the ratios of the soybean oil, the palm oil, the rapeseed oil, and the coconut oil determined by the preset mathematical model provided in the embodiment of the present invention all fall within the range of the indexes of the breast milk, and it can be found from table 5 that the similarity score between the breast milk substitute fat prepared by the base oil in the specific embodiment 1 and the mother milk fat is the highest, so that the breast milk substitute fat prepared by the ratios of the soybean oil, the palm oil, the rapeseed oil, and the coconut oil determined by the preset mathematical model in the embodiment of the present invention has obvious superiority, and the breast milk substitute fat can be prepared by an objective, scientific, and comprehensive physical blending method.
Specific example 2
The selected preset base oil comprises soybean oil, peanut oil, corn oil, palm oil, rapeseed oil, coconut oil and structural grease in the table 1, and the proportion of each base oil is determined by a preset mathematical model provided by the embodiment of the invention as follows: soybean oil: peanut oil: corn oil: palm oil: rapeseed oil: coconut oil: structural fat 11.44%: 2.60%: 1.71%: 0.53%: 6.12%: 14.41%: 63.20 percent. With this ratio of base oil, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk substitute fat is shown in tables 6 to 8.
Comparative example 2-1
Taking soybean oil, peanut oil, corn oil, palm oil, rapeseed oil, coconut oil and structural fat as base oil for preparing breast milk substitute fat, and blending the soybean oil in a ratio of: peanut oil: corn oil: palm oil: rapeseed oil: coconut oil: structural fat 6%: 8%: 12%: 11%: 11%: 9%: 43%, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substituted fat is shown in tables 6 to 8 below.
Comparative examples 2 to 2
Taking soybean oil, peanut oil, corn oil, palm oil, rapeseed oil, coconut oil and structural fat as base oil for preparing breast milk substitute fat, and blending the soybean oil in a ratio of: peanut oil: corn oil: palm oil: rapeseed oil: coconut oil: structural fat 1%: 8%: 7%: 6%: 1%: 4%: 73%, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substituted lipids are shown in tables 6 to 8 below.
TABLE 6 Total fatty acid composition (%)
Total fatty acids | Specific example 2 | Comparative example 2-1 | Comparative examples 2 to 2 | Milk fat |
C10:0 | 0.83 | 0.52 | 0.23 | 0.06~2.21 |
C12:0 | 6.75 | 4.22 | 1.87 | 1.19~8.51 |
C14:0 | 2.70 | 1.79 | 0.80 | 2.20~7.93 |
C16:0 | 31.13 | 28.28 | 36.76 | 15.07~22.62 |
C16:1 | 0.02 | 0.03 | 0.01 | 0.98~2.39 |
C18:0 | 2.55 | 2.59 | 2.45 | 3.67~8.32 |
C18:1 | 34.26 | 36.84 | 37.36 | 26.04~37.27 |
C18:2 | 19.28 | 22.99 | 19.59 | 14.19~25.52 |
C18:3 | 1.20 | 1.55 | 0.34 | 0.76~1.73 |
TABLE 7 fatty acid composition in sn-2 site (%) -of mother milk substitute fat in specific example 2 and comparative examples 2-1 and 2-2
sn-2 fatty acid | Specific example 2 | Comparative example 2-1 | Comparative examples 2 to 2 | Milk fat |
C12:0 | 10.24 | 6.40 | 2.84 | 0.65~10.24 |
C14:0 | 1.52 | 0.98 | 0.44 | 4.46~15.52 |
C16:0 | 56.39 | 40.07 | 65.40 | 43.31~58.37 |
C16:1 | 0 | 0 | 0 | 1.37~2.74 |
C18:0 | 2.12 | 1.65 | 2.24 | 1.21~2.56 |
C18:1 | 14.36 | 25.44 | 15.94 | 6.98~17.23 |
C18:2 | 13.98 | 23.64 | 12.87 | 3.31~13.42 |
TABLE 8 triglyceride composition of mother milk substitute fat (%)
Triglycerides | Specific example 2 | Comparative example 2-1 | Comparative examples 2 to 2 | Milk fat |
LaLaO | 0.21 | 0.13 | 0.06 | 0~2.21 |
CaPL | 0 | 0 | 0 | 0~4.88 |
LLL | 2.32 | 4.78 | 2.57 | 0~3.49 |
LaOL | 0 | 0 | 0 | 0.30~7.20 |
CaPO | 0 | 0 | 0 | 0~8.52 |
OLL | 3.70 | 6.76 | 3.54 | 2.90~10.35 |
PLL | 3.31 | 4.19 | 3.13 | 0~11.39 |
MOL | 0 | 0 | 0 | 0~13.58 |
LaOO | 0 | 0 | 0 | 0.21~3.42 |
POLa | 0 | 0 | 0 | 4.35~10.78 |
OPL | 20.14 | 17.05 | 23.35 | 17.85~33.02 |
PPL | 4.88 | 5.07 | 6.37 | 1.57~7.25 |
MPO | 0 | 0 | 0 | 0.36~3.17 |
OOO | 3.73 | 7.44 | 3.11 | 0.52~3.73 |
OPO | 24.86 | 20.33 | 30.18 | 6.81~24.86 |
PPO | 14.43 | 14.41 | 19.01 | 1.56~8.07 |
POS | 0.36 | 0.52 | 0.41 | 0~2.83 |
The similarity scores of breast milk-substituted fats prepared by mixing vegetable fats and structural fats (modified fats) are shown in table 9:
TABLE 9 similarity score between mother milk fat and breast milk fat prepared in specific example 2, comparative examples 2-1, 2-2
Degree of similarity | Specific example 2 | Comparative example 2-1 | Comparative examples 2 to 2 |
Total fatty acids | 81.54 | 81.11 | 65.13 |
sn-2 fatty acid | 75.70 | 55.81 | 71.12 |
Triglycerides | 71.83 | 63.56 | 69.33 |
Total score | 76.36 | 66.83 | 68.53 |
As can be seen from tables 6 to 8, the indexes of total fatty acids, the indexes of sn-2 fatty acids and the indexes of triglycerides of the breast milk substitute fat prepared by the ratio of soybean oil, peanut oil, corn oil, palm oil, rapeseed oil, coconut oil and structural fat determined by the preset mathematical model provided by the embodiment of the invention all fall into the range of the indexes of the breast milk, and as can be seen from table 9, the similarity score between the breast milk substitute fat prepared using the base oil of the specific example 2 and the mother milk fat is the highest, therefore, the breast milk substitute fat prepared by the ratio of the soybean oil, the peanut oil, the corn oil, the palm oil, the rapeseed oil, the coconut oil and the structural fat determined by the preset mathematical model has obvious superiority, and can be prepared by an objective, scientific and comprehensive physical blending method.
Specific example 3
The selected preset base oil comprises peanut oil, palm oil, rapeseed oil, coconut oil, golden pompano fish oil and tilapia oil in the table 1, and the proportion of each base oil is determined by a preset mathematical model provided by the embodiment of the invention as follows: peanut oil: palm oil: rapeseed oil: coconut oil: golden pomfret oil: tilapia mossambica oil 11%: 11%: 11%: 4%: 44%: 19% by weight of the base oil, the compositions of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substitute fat are shown in tables 10 to 12.
Comparative example 3-1
Taking peanut oil, palm oil, rapeseed oil, coconut oil, golden pomfret oil and tilapia mossambica oil as base oil for preparing breast milk substitute fat, and blending the peanut oil: palm oil: rapeseed oil: coconut oil: golden pomfret oil: tilapia mossambica oil 11%: 11%: 11%: 4%: 44%: 19%, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substituted lipids are shown in tables 10 to 12 below.
Comparative examples 3 to 2
Taking peanut oil, palm oil, rapeseed oil, coconut oil, golden pomfret oil and tilapia mossambica oil as base oil for preparing breast milk substitute fat, and blending the peanut oil: palm oil: rapeseed oil: coconut oil: golden pomfret oil: tilapia mossambica oil 6%: 1%: 6%: 2%: 84%: 1%, the composition of the total fatty acids, sn-2 fatty acids and triglycerides of the resulting breast milk-substituted lipids are shown in tables 10 to 12 below.
TABLE 10 Total fatty acid composition (%)
Total fatty acids | Specific example 3 | Comparative example 3-1 | Comparative examples 3 to 2 | Milk fat |
C10:0 | 0.80 | 0.23 | 0.12 | 0.06~2.21 |
C12:0 | 6.70 | 2.05 | 1.15 | 1.19~8.51 |
C14:0 | 4.23 | 2.26 | 2.02 | 2.20~7.93 |
C16:0 | 23.20 | 22.49 | 22.09 | 15.07~22.62 |
C16:1 | 2.27 | 2.01 | 2.38 | 0.98~2.39 |
C18:0 | 4.67 | 4.44 | 4.62 | 3.67~8.32 |
C18:1 | 25.42 | 34.41 | 29.71 | 26.04~37.27 |
C18:2 | 21.22 | 22.67 | 25.03 | 14.19~25.52 |
C18:3 | 3.32 | 3.65 | 4.14 | 0.76~1.73 |
TABLE 11 fatty acid composition in sn-2 position (%)
sn-2 fatty acid | Specific example 3 | Comparative example 3-1 | Comparative examples 3 to 2 | Milk fat |
C12:0 | 10.24 | 3.16 | 1.85 | 0.65~10.24 |
C14:0 | 4.06 | 2.66 | 2.94 | 4.46~15.52 |
C16:0 | 31.34 | 27.45 | 32.33 | 43.31~58.37 |
C16:1 | 2.08 | 1.68 | 2.28 | 1.37~2.74 |
C18:0 | 0.58 | 0.55 | 0.47 | 1.21~2.56 |
C18:1 | 8.82 | 21.07 | 9.80 | 6.98~17.23 |
C18:2 | 14.72 | 21.22 | 17.77 | 3.31~13.42 |
TABLE 12 triglyceride composition of mother milk substitute fat (%)
The similarity scores of the breast milk substitute fat prepared by mixing vegetable fat with the fish oil rich in OPO and OPL are shown in Table 13.
TABLE 13 similarity score between mother milk fat and breast milk fat prepared in specific example 3, comparative examples 3-1, 3-2
Degree of similarity | Specific example 3 | Comparative example 3-1 | Comparative examples 3 to 2 |
Total fatty acids | 89.50 | 88.89 | 87.61 |
sn-2 fatty acid | 85.95 | 69.72 | 78.14 |
Triglycerides | 76.30 | 69.91 | 72.18 |
Total score | 83.92 | 76.17 | 79.31 |
As can be seen from tables 10 to 12, the indexes of total fatty acids, the indexes of sn-2 fatty acids, and the indexes of triglycerides of the breast milk substitute fat prepared by the ratios of peanut oil, palm oil, rapeseed oil, coconut oil, golden pomfret oil, and tilapia oil determined by the preset mathematical model provided in the embodiment of the present invention all fall within the range of the indexes of the breast milk, and it can be found from table 13 that the similarity score between the breast milk substitute fat prepared by the base oil in the specific embodiment 3 and the mother milk fat is the highest, so that the breast milk substitute fat prepared by the ratios of soybean oil, palm oil, rapeseed oil, and coconut oil determined by the preset mathematical model of the embodiment of the present invention has obvious superiority, and can be prepared by an objective, scientific, and comprehensive physical blending method.
The preparation method of the breast milk substitute fat provided by the embodiment of the invention can determine the proportion of each base oil in the preset base oil by adopting the preset mathematical model, is accurate and efficient, and is not influenced by the base oil, so that the proportion of various preset base oils meeting the requirements can be determined, and the preparation method has important significance for simulating breast milk fat in the prior art.
In addition, an embodiment of the present invention provides a device for preparing breast milk substitute fat, which is shown in fig. 2 and includes:
the identification module 21 is used for determining preset base oil adopted by the synthetic breast milk substitute fat;
the calculation module 22 is used for determining the proportion of each base oil by using a preset mathematical model, so that the content of a preset index in the composition synthesized according to the proportion is within the content range of a corresponding index in breast milk;
and the proportioning module 23 is used for proportioning and synthesizing the breast milk substitute fat according to the proportion of each base oil determined by the preset model.
In the embodiment of the present invention, the preset mathematical model adopted by the calculation module is:
wherein x isjThe minimum deviation value of m indexes in the mother cream is more than or equal to 0, j is 1,2, … …, n and D, and the minimum deviation value is 0; ciIs the deviation value of index i; m is the total number of selected indexes in the mother cream; n is the total amount of base oil; a. theijThe content of the index i in the jth base oil is expressed as a matrix; x is the number ofjThe percentage content of the jth base oil after blending; zu ZuiAnd ZdiThe upper limit and the lower limit of the index i in the breast milk fat are respectively.
According to the preparation device of the breast milk substitute fat, provided by the embodiment of the invention, the calculation module can determine the proportion of each base oil in the preset base oil by adopting the preset mathematical model, is accurate and efficient, and is not influenced by the base oil, so that the proportion of various preset base oils meeting the requirements can be determined, and the preparation device has important significance for simulating breast milk fat in the prior art.
It should be noted that, in the embodiments of the present invention, the term "connected" may be a direct connection or an indirect connection. The connection can be through a wire or other connection structure, such as a hose. The present solution is not particularly limited.
It should also be noted that the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (10)
1. A method for preparing a fat substitute for human milk, the method comprising:
determining preset base oil adopted by the synthetic breast milk substitute fat;
determining the proportion of each base oil by a preset mathematical model, so that the content of a preset index in the composition synthesized according to the proportion is within the content range of a corresponding index in breast milk;
and (4) synthesizing the breast milk substitute fat according to the proportion of the base oil determined by the preset model.
2. The method of claim 1, wherein the predetermined mathematical model is:
wherein x isjThe minimum deviation value of m indexes in the mother cream is more than or equal to 0, j is 1,2, … …, n and D, and the minimum deviation value is 0; ciIs the deviation value of index i; m is the total number of selected indexes in the mother cream; n is the total amount of base oil; a. theijThe content of the index i in the jth base oil is expressed as a matrix; x is the number ofjThe percentage content of the jth base oil after blending; zu ZuiAnd ZdiThe upper limit and the lower limit of the index i in the breast milk fat are respectively.
3. The method of claim 2, wherein the predetermined indicators comprise total fatty acids, sn-2 fatty acids and triglycerides of milk fat.
4. The method of claim 3, wherein the total fatty acids comprise: capric acid (Ca), lauric acid (La), myristic acid (M), palmitic acid (P), palmitoleic acid (Po), oleic acid (O), linoleic acid (L), and linolenic acid (LNA).
5. The method according to claim 3, wherein the sn-2 fatty acid comprises lauric acid (La), myristic acid (M), palmitic acid (P), palmitoleic acid (Po), oleic acid (O), and linoleic acid (L).
6. The method of claim 3, wherein the triglycerides comprise LaLaLaO, CaPL, LLL, LaOL, CaPO, OLL, PLL, MOL, LaOL, POLa, OPL, PPL, MPO, OOO, OPO, PPO and POS.
7. The method of claim 2, wherein the pre-set base oils comprise soybean oil, palm oil, rapeseed oil, and coconut oil;
the proportion of each base oil determined by a preset model is soybean oil: palm oil: rapeseed oil: coconut oil 25.03%: 39.17%: 6.71%: 29.09 percent.
8. The method of claim 2, wherein the pre-set base oil comprises soybean oil, peanut oil, corn oil, palm oil, rapeseed oil, coconut oil, and structured fats;
the proportion of each base oil determined by a preset model is soybean oil: peanut oil: corn oil: palm oil: rapeseed oil: coconut oil: structural fat 11.44%: 2.60%: 1.71%: 0.53%: 6.12%: 14.41%: 63.20 percent.
9. The method of claim 2, wherein the pre-set base oil comprises peanut oil, palm oil, rapeseed oil, coconut oil, golden pomfret oil, and tilapia oil;
the proportion of each base oil determined by a preset model is peanut oil: palm oil: rapeseed oil: coconut oil: golden pomfret oil: 1.3% of tilapia mossambica oil: 6.13%: 0.8%: 13.86%: 69.19%: 8.72 percent.
10. A device for preparing a fat substitute for human milk, comprising:
the identification module is used for determining preset base oil adopted by the synthetic breast milk substitute fat;
the calculation module is used for determining the proportion of each base oil by using a preset mathematical model so that the content of a preset index in the composition synthesized according to the proportion is within the content range of a corresponding index in breast milk;
and the proportioning module is used for proportioning and synthesizing the breast milk substitute fat according to the proportion of each base material oil determined by the preset model.
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