CN1117548C - Woundless blood sugar measuring apparatus - Google Patents
Woundless blood sugar measuring apparatus Download PDFInfo
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- CN1117548C CN1117548C CN 98111360 CN98111360A CN1117548C CN 1117548 C CN1117548 C CN 1117548C CN 98111360 CN98111360 CN 98111360 CN 98111360 A CN98111360 A CN 98111360A CN 1117548 C CN1117548 C CN 1117548C
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- blood sugar
- iraser
- chopper
- grating
- infrared
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Abstract
The present invention relates to a woundless blood sugar measuring instrument which belongs to blood sugar measuring instruments. The present invention comprises two structures for realizing woundless blood sugar measurement: (1) a probe is connected to the existing blood sugar meter, and an oxygen electrode and glucase are arranged in the probe; the probe is connected with an air pump; after the probe is closely attached to fingers of a measured person, the exuding tissue fluid from the fingers acts on the glucase, and thus, the blood sugar meter can measure the blood sugar concentration; (2) an infrared beam of a controlled laser is divided into two bundles of light by a light grating and a spectroscope, one bundle reaches to a wave chopper by the fingers, and the other bundle reaches to the wave chopper by a reference pool. The wave chopper respectively sends the two bundles of light to an infrared receiver, the infrared receiver sends signals to a microprocessor executing operation by combining a database, and a display device is used for displaying measurement results.
Description
Technical field
The present invention relates to a kind of glucometer, particularly Woundless blood sugar measuring apparatus.
Background technology
At present, measuring blood sugar concentration in the blood of human body, mainly is to adopt blood-glucose meter, and there is platinum and silver chloride--silver electrode the blood-glucose meter outside; There is single-chip microcomputer inside, and the electrode output lead is connected with single-chip microcomputer; Numerical value display and status displays are arranged on the panel.During test, extract person's to be measured blood, the blood that extracts is coated on the reagent paper in the blood-glucose meter, utilize in glucose in the blood and the blood-glucose meter glucase on the reagent paper to have an effect, promptly utilize the glucose oxidase film technology, the reagent paper of having an effect is on the electrode of blood-glucose meter, promptly by platinum and silver chloride---produce electric current on the electrode that silver is formed, after the electric current that is produced is calculated by the single-chip microcomputer in the blood-glucose meter, convert digital signal to, shown by liquid crystal display, this numeral that shows is exactly the blood sugar concentration in gauger's blood.As measuring one group of complete data, generally need in one day, measure 8 times, every measurement once will be taken out blood one time, promptly need to extract 8 blood of patient and just can finish, and the patient infection chance increases, and brings very big misery to patient simultaneously.
Summary of the invention
The objective of the invention is to provide a kind of patient's no pain, do not need to extract the Woundless blood sugar measuring apparatus that patient blood can be measured blood sugar concentration in the patient blood.
Realize the version of the object of the invention: an iraser is arranged, and iraser is connected with the iraser power supply, on the light path of iraser grating is arranged; Spectroscope is arranged behind the grating, spectroscope is divided into two bundle infrared beams with iraser, a branch ofly point the arrival chopper by the tester, another bundle arrives reference cell by illuminator, reference cell exports chopper to, infrared remote receiver is arranged behind the chopper, infrared remote receiver converts the infrared beam that receives to current signal and delivers to microprocessor, there is a data base to be connected with microprocessor, microprocessor and data base handle the current signal of infrared beam jointly, microprocessor has five tunnel output control signals, controls the iraser power supply respectively, grating, reference cell, chopper, printer; One tunnel shows signal is used for display result.
Described iraser power supply can be controlled the spacing frequency of iraser emission.
Described grating has a motor, connects the grating disk on the motor, on the grating disk gratings strips is arranged, the gratings strips grizzly bar that 200 concentrics are arranged of having an appointment, and grizzly bar is through laser scoring, and the grating disk is rotated by micro processor controls.
Dress Glucose Liquid in the described reference cell, its varied in thickness is adjustable, makes its thickness and calculate concentration suitable.
Described chopper has a motor, connects a blade on the motor, and blade is the fence gate of a controlled rotation, alternately selects two bundle infrared beams to inject, and the infrared beam by chopper is received by infrared remote receiver.
Beneficial effect: owing to adopted such scheme, opening power, iraser sends infrared beam under the control of Laser Power Devices, infrared beam directly enters grating, under the effect of grating, form narrower incident beam, the change of grating is associated by microcomputer control and with the change of infrared wavelength, be divided into two bundle infrared beams through spectroscopical effect, a branch ofly enter the adjustable reference cell of thick change through the illuminator effect and enter chopper, another bundle arrives chopper by gauger's finger, two bundle infrared beams arrive chopper simultaneously, the fence gate of the controlled rotation of chopper alternately selects two bundle infrared beams to inject, and selecteed infrared beam arrives infrared remote receiver at last, infrared remote receiver converts infrared beam to current signal and sends into microprocessor, through data base's combined effect, carry out numerical calculation, at last the blood sugar concentration result is shown in display, printer prints goes out the result simultaneously, has reached purpose of the present invention.
Adopt the advantage of such scheme to be: (1) has solved when checking the blood glucose blood drawing damage to human body; (2) lowered the infection probability; (3) accuracy rate raising, time shorten; (4) check that for family blood glucose provides convenience; (5) success rate of operation and the wound healing for surgical patient provides reliable way; (6) greatly reduce the inspection cost; (7) reduced the pollution of reagent to environment.
The clinical value of such scheme: (1) has solved present blood glucose and has dynamically guarded, and takes out the drawback of 8 blood in one day; (2) solved can't monitor in the operation stress blood glucose level; (3) solved real-time and dynamic blood sugar concentration difficulty (promptly going out the result 1 second); (4) for diabetes patient's diagnosis provides extremely important means, by it, with the mode of monitoring in 24 hours, to determine insulin-dependent and two kinds of causes of disease of non-insulin-depending type; Physiological still is a pathologic blood glucose; Stress type still be the endocrine regulation type; (5) instruct clinical application, for the doctor provides the medication Evaluation on effect; (6) in operation can for anaesthetist, operation teacher provide blood glucose stress parameter, understand patient endocrine situation and assess wound healing state by it; (7) for the patient of diabetic ketoacidosis and stupor, rescue extremely important means are provided, saved a large amount of time; (8) to the sick needed continuous care of relevant blood glucose, improved diagnostic strength.
Description of drawings
Fig. 1 is the block diagram of version of the present invention.
Fig. 2 is chopper blade figure in the version of the present invention.
Fig. 3 is grating pie chart in the version of the present invention.
Fig. 4 is the detailed circuit diagram of version of the present invention.
The specific embodiment
Embodiment 1: an iraser 14 is arranged, and iraser 14 is subjected to 15 controls of iraser power supply, and iraser power supply 15 can be controlled the transmission interval frequency of iraser 14.
Grating 16 is arranged on the light path of iraser 14, grating 16 has a motor, and motor is subjected to microprocessor 24 controls, the position of rotation and the positive and negative direction of microprocessor 24 control motors, connect the grating disk on the motor, post gratings strips on the grating disk, the gratings strips grizzly bar that 200 concentrics are arranged of having an appointment, grizzly bar is through laser scoring, the grating disk is rotated by micro processor controls, spectroscope 17 is arranged behind the grating 16,, form the narrower incidence point of wavelength through the effect of grating 16.
Tell two bundle infrared beams through the effect of spectroscope 17, a branch ofly point 19 by the tester and arrive choppers 20, this bundle infrared beam is to erythrocyte specific wavelength sensitivity, another bundle arrives reference cell 21 by illuminator 18, this bundle infrared beam is to the specific wavelength sensitivity of glucose, and two bundle infrared beams only have very little absorbance to other wavelength.
Reference cell 21 exports chopper 20 to, dress Glucose Liquid in the reference cell 21, and its varied in thickness is adjustable, makes its thickness and calculate concentration suitable.
Chopper 20 has a motor, motor is subjected to microprocessor 24 controls, the direction of rotation and the rotating speed of microprocessor 24 control motors, connect a blade on the motor, blade is the fence gate of a controlled rotation, alternately selects two bundle infrared beams to inject, by the infrared beam of chopper 20, received by infrared remote receiver 22, infrared remote receiver 22 converts the infrared beam that receives to electric current and delivers to microprocessor 24.
There is a data base 23 to be connected outside the microprocessor 24 with microprocessor 24, microprocessors support 24, microprocessor 24 will be pointed 19 the current signal that is converted to by infrared beam and handle, draw the about 200 nanometer bandwidth of different wave length, be complex superposition spectrum, this moment microprocessor 24 maintenance data storehouses 23, carry out the least square fitting computing, glucose and blood mixture are handled as two kinds of independent reagent, thereby the concentration of calculating, obtain a result,, make reference cell 21 interior Glucose Liquid thickness and calculate concentration suitable again by microprocessor 24 control reference cell 21 and varied in thickness, microprocessor 24 reuse subtract each other the differential method and come assay, the result is normal: promptly under the normal physiological under a certain specific wavelength, by a large amount of experiment experiences sum up and on, very little for the mixed body permeability of blood, and glucose is very big, very big with blood and body permeability, and glucose is less, this moment, result of calculation was suitable, microprocessor 24 stops search, and confirms currency; Result error: may get rid of and disturb because the pathology reason changes or injects other medicine and cause interference, and computer is searched for specific wavelength again in conjunction with database feature, uses Array Method to calculate multi-element type one time again.
Microprocessor 24 is with result's output, and output has five tunnel control signals, controls iraser power supply 15, grating 16, reference cell 21, chopper 20, printer 26 respectively; One tunnel shows signal, control display 25 is used for display result.
Iraser 14 is measured the feasibility of blood sugar for human body, and ultimate principle is lambert-Beer law, the thick proportional relation that becomes of absorbance and solution concentration and liquid layer, and the Mathematical treatment pattern is a least square curve fitting.In actual use, blood as solvent, creatinine, albumin, bilirubin, ammonia and various electrolyte etc. in the blood, common stack spectrum with hemoglobin is regarded the formed spectrum of a kind of material as, the spectrum of glucose as with above spectrographic stack, use least square curve fitting, but because in human body, various physiology, pathological change, may significantly raise by certain composition in the blood habitually in the past, or the injection all ingredients, microprocessor 24 is when analyzing above-mentioned data, must obtain data base 23 support, just can finish the work of treatment of data.
Claims (5)
1, a kind of Woundless blood sugar measuring apparatus is characterized in that: an iraser is arranged, and iraser is connected with the iraser power supply, on the light path of iraser grating is arranged; Spectroscope is arranged behind the grating, spectroscope is divided into two bundle infrared beams with light path, a branch ofly point the arrival chopper by the tester, another bundle arrives reference cell by illuminator, reference cell exports chopper to, infrared remote receiver is arranged behind the chopper, infrared remote receiver converts the infrared beam that receives to current signal and delivers to microprocessor, there is a data base to be connected with microprocessor, microprocessor and data base handle the current signal of infrared beam jointly, microprocessor has five tunnel output control signals, controls the iraser power supply respectively, grating, reference cell, chopper, printer; One tunnel shows signal is used for display result.
2, require 1 described Woundless blood sugar analyzer according to power, it is characterized in that: described iraser power supply can be controlled the spacing frequency of iraser emission.
3, Woundless blood sugar analyzer according to claim 1, it is characterized in that: described grating has a motor, connect the grating disk on the motor, on the grating disk gratings strips is arranged, the gratings strips grizzly bar that 200 concentrics are arranged of having an appointment, grizzly bar is through laser scoring, and the grating disk is rotated by micro processor controls.
4, Woundless blood sugar measuring apparatus according to claim 1 is characterized in that: dress Glucose Liquid in the described reference cell, its varied in thickness is adjustable, makes its thickness and calculate concentration suitable.
5, Woundless blood sugar measuring apparatus according to claim 1 is characterized in that: described chopper has a motor, connects a blade on the motor, blade is the fence gate of a controlled rotation, alternately select two bundle infrared beams to inject, the infrared beam by chopper is received by infrared remote receiver.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98111360 CN1117548C (en) | 1998-06-09 | 1998-06-09 | Woundless blood sugar measuring apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98111360 CN1117548C (en) | 1998-06-09 | 1998-06-09 | Woundless blood sugar measuring apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1204496A CN1204496A (en) | 1999-01-13 |
| CN1117548C true CN1117548C (en) | 2003-08-13 |
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ID=5221348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98111360 Expired - Fee Related CN1117548C (en) | 1998-06-09 | 1998-06-09 | Woundless blood sugar measuring apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1117548C (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544193B2 (en) * | 1996-09-04 | 2003-04-08 | Marcio Marc Abreu | Noninvasive measurement of chemical substances |
| BRPI0418899A (en) * | 2004-06-07 | 2007-11-27 | Solianis Holding Ag | method and device for determining a living tissue parameter |
| CN103908264B (en) * | 2012-12-28 | 2016-05-11 | 台医光电科技股份有限公司 | Non-invasive glucose monitoring device |
| CN107427266B (en) * | 2015-01-21 | 2021-12-03 | 国立研究开发法人量子科学技术研究开发机构 | Blood substance concentration measuring device and blood substance concentration measuring method |
| CN110269627A (en) * | 2019-08-02 | 2019-09-24 | 普乐药业有限公司 | Blood sugar measuring system and method |
-
1998
- 1998-06-09 CN CN 98111360 patent/CN1117548C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1204496A (en) | 1999-01-13 |
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