CN111714172A

CN111714172A - Suture suitable for parenchymal organ bleeding blood vessel anastomosis

Info

Publication number: CN111714172A
Application number: CN202010731940.3A
Authority: CN
Inventors: 李明
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-07-27
Filing date: 2020-07-27
Publication date: 2020-09-29
Anticipated expiration: 2040-07-27
Also published as: CN111714172B

Abstract

A suture suitable for anastomosis of bleeding blood vessels of parenchymal viscera. The hemostatic and anti-inflammatory drug suture comprises a suture, and a suture needle and a suture fixing block which are arranged at two ends of the suture, wherein the suture comprises a wire body core part, a hemostatic and anti-inflammatory drug interlayer and a gelatin film layer which are arranged in an inner and outer circumferential direction; the core part of the line body is formed by weaving absorbable hemostatic sponge particles wrapped by two line bodies I, and the two line bodies I are polyglycolic acid lines; or the core part of the thread body is formed by weaving three thread bodies, wherein the three thread bodies are respectively a thread body II made of absorbable hemostatic sponge, a thread body III of polyglycolic acid and a piece of gut thread, and the three are tightly twisted together; the suture fixing block is a solid body made of collagen. The invention can effectively reduce the condition of needle eye bleeding after suturing, shorten the recovery period and improve the postoperative recovery effect.

Description

Suture suitable for parenchymal organ bleeding blood vessel anastomosis

Technical Field

The invention relates to a suture for operation, in particular to a suture suitable for anastomosis of bleeding blood vessels of parenchymal viscera, belonging to the technical field of medical treatment.

Background

Vascular anastomosis is one of the most common surgical modalities in the clinic. Generally, the tumor usually invades the blood vessel, the pathological blood vessel needs to be removed, and the end of the blood vessel is anastomosed. In addition, for the surgical treatment of diseases or injuries of main arteries and veins, blood flow needs to be reconstructed by methods such as direct repair, patch forming or vascular transplantation, and vascular suturing and anastomosis are also one of the basic techniques in the whole surgical operation.

Regardless of the type of vascular anastomosis that is required, a suturing procedure for the severed end surfaces of the vessel is required, and minimizing needle hole bleeding caused by the suture passing through the vessel wall is one of the important considerations for the success of the procedure.

In addition, the recovery time of the vascular anastomosis is relatively long, and complete recovery generally takes up to about half a year. And can not be subjected to violent movement within a later period of time so as to prevent the blood vessels at the anastomotic site from being ruptured to cause bleeding and influence the survival rate of the operation.

Disclosure of Invention

In order to overcome the defects in the prior art, the invention provides the suture suitable for the blood vessel anastomosis of the bleeding of the parenchyma viscera, the suture is used for the blood vessel anastomosis, the condition of the needle eye bleeding after the suture can be effectively reduced, the recovery period can be shortened, and the postoperative recovery effect can be improved.

The invention adopts a technical scheme for solving the technical problems that: the hemostatic sponge particle suture comprises a suture, and a suture needle and a suture fixing block which are arranged at two ends of the suture, wherein the suture comprises a line body core part, a hemostatic and anti-inflammatory drug interlayer and a gelatin film layer which are arranged in an inner and outer circumferential direction, the line body core part is formed by wrapping absorbable hemostatic sponge particles with two line bodies I and weaving, and the two line bodies I are polyglycolic acid lines; the suture fixing block is a solid body made of collagen.

The other technical scheme adopted by the invention for solving the technical problem is as follows: the hemostatic sponge suture comprises a suture, and a suture needle and a suture fixing block which are arranged at two ends of the suture, wherein the suture comprises a line body core part, a hemostatic and anti-inflammatory drug interlayer and a gelatin film layer which are arranged circumferentially inside and outside, the line body core part is formed by weaving three lines, the three lines are respectively a line body II made of absorbable hemostatic sponge, a line body III of polyglycolic acid and a piece of intestinal line, and the three lines are twisted together in a close manner from top to bottom; the suture fixing block is a solid body made of collagen.

Compared with the prior art, the suture line suitable for the anastomosis of the bleeding vessels of the parenchyma viscera innovatively forms a multistage hemostasis mechanism on different space and time dimensions. In terms of space, the suture fixing block at the tail end is firstly seen along the whole length, the suture fixing block is convenient to be absorbed by a body due to the adoption of a collagen solid body, plays a role in pressing hemostasis in the suturing process, and then looks at the three-dimensional structure of the suture, on one hand, the suture fixing block comprises a line body core part, a hemostatic and anti-inflammatory drug interlayer and a gelatin film layer which are arranged in an inner-outer annular mode, the gelatin film layer enables gaps left around the suture after the suture penetrates through a graft to be small, so that needle eyes generate relatively less bleeding, on the other hand, the line body core part is formed by weaving absorbable hemostatic sponge particles wrapped by two lines I, or the line body core part is formed by weaving three lines, the three lines are respectively a line body II made of absorbable hemostatic sponge, a line body III of polyglycolic acid and an intestinal line, and the two different absorbable hemostatic sponge structural forms play a role in hemostasis, the body II or the granular shape containing the absorbable hemostatic sponge material can generate volume expansion after meeting blood, and plays the role of hemostasis again in the inner layer. From the time, the gelatin film layer, the line body core portion all can be absorbed in vivo in the material, nevertheless establish the difference owing to the concrete selection in the material, consequently formed different absorption time, the time of just having limited the play effect in proper order in time, carry out preliminary hemostasis and antiphlogosis through hemostasis antiphlogistic medicine intermediate layer earlier in the short time of postoperative promptly, utilize the absorbable hemostatic sponge of line body core portion to deal with possible external a small amount of bleeding that produces again in the recovery period, strengthen the antiphlogosis simultaneously, promote the recovery, thereby effectively avoided the back of sewing up because of the consequence that the pinhole hemorrhage caused, the duration of recovery period has been shortened.

Drawings

The invention is further illustrated with reference to the following figures and examples.

Fig. 1 is a schematic structural diagram of an embodiment of the present invention.

FIG. 2 is a cross-sectional view of a suture in one embodiment of the present invention.

FIG. 3 is a schematic view of the mounting structure of the suture anchor block in one embodiment of the present invention.

Figure 4 is a schematic structural view of a wire body core in one embodiment of the invention.

Figure 5 is a schematic structural view of a wire body core in another embodiment of the invention.

In the figure, 1, suture needle 2, suture 201, thread body core 2011, absorbable hemostatic sponge particles 2012, thread body I, 2012-1, thread body II, 2012-2, thread body III, 2012-3, gut 202, hemostatic and anti-inflammatory drug interlayer 203, gelatin membrane layer 3, suture fixing block 301 and tip.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, belong to the scope of the present invention.

Fig. 1 to 4 show schematic structural diagrams of a preferred embodiment of the present invention, in which a suture suitable for anastomosis of bleeding blood vessels of a parenchymal organ comprises a suture 2, and a suture needle 1 and a suture fixing block 3 arranged at two ends of the suture, wherein the suture 2 comprises a wire body core 201, a hemostatic and anti-inflammatory drug interlayer 202 and a gelatin film layer 203 (see fig. 2) which are circumferentially arranged inside and outside. The suture body core 201 is used as a main body part of the suture 2 and is formed by wrapping absorbable hemostatic sponge particles 2011 with two suture bodies I2012 and weaving, wherein the two suture bodies I2012 are polyglycolic acid threads (see figure 4); the polyglycolic acid thread is an absorbable material, causes little tissue reaction and can be completely absorbed by tissues after about 60 to 90 days; the gelatin film layer 203 is used as the first structure layer of the suture 2 contacting with the tissue wound, is safe and reliable, has no antigenicity, does not generate anaphylactic reaction, has no inflammatory reaction to the surrounding tissue when filling a pinhole, and utilizes the poor mechanical property, is easy to damage after encountering blood, has poor adhesion and is easy to fall off, so when the suture bleeding amount is a little bit larger, the gelatin film layer 203 can be quickly opened and separated, and then the opening of the hemostatic and anti-inflammatory drug interlayer 202 is facilitated, at the time, the drugs in the hemostatic and anti-inflammatory drug interlayer 202 can perform the therapeutic or preventive hemostatic and anti-inflammatory functions, and the tissue healing can be accelerated. The blood enters the absorbable hemostatic sponge particles 2011 after passing through the two-strand body I2012, and the absorbable hemostatic sponge particles 2011 expand in volume after encountering blood, which is equivalent to the effect of compression hemostasis. The suture fixing block 3 is a solid body made of collagen, the suture fixing block 3 is finally positioned at the tail end of the suture 2 and mainly plays a role in fixing the suture 2, and in the invention, the suture fixing block is also used as a structure for assisting hemostasis because the solid body extrudes tissues when the suture 2 is pulled and tensioned; in addition, the collagen material has the advantages of biodegradability, low antigenicity, cell adaptability, biocompatibility, cell proliferation promoting effect, platelet aggregation accelerating effect and the like, can complete rapid and efficient hemostasis on wound surfaces, and can be degraded in a body.

In a preferred embodiment of the invention, the suture needle 1 and the suture 2 are integrally connected, namely the suture 2 is embedded in the tail needle eye of the suture needle 1 and is integrated, so that the suture needle can be used without carrying out threading operation before use, the whole disinfection can be carried out between the suture needle 1 and the suture 2, the infection chance is reduced, no obvious transition node exists at the joint of the suture needle 1 and the suture 2, and the leakage of blood after suturing can be reduced. A further improvement is that to minimize needle hole bleeding caused by suture 2 passing through the vessel wall, a circular needle is selected, with the arc being 1/2 or 3/8, and the suture 2 being selected to be as thin as possible.

In a preferred embodiment of the present invention, the external shape of the suture fixing block 3 is preferably cubic or boat-anchor-shaped, because such a structure has a large contact surface with the tissue and stronger fixing force, thereby ensuring the fixation of the suture 2 during and after the suture is completed.

Referring to fig. 3, in the embodiment of the present invention, the suture fixing block 3 is slidably mounted on the suture 2, and the initial mounting position thereof is at one end close to the suture needle 1, the suture fixing block 3 is sleeved on the suture, and the inner surface of the suture fixing block 3 contacting with the suture 2 is provided with a tip portion 301, the front end of the tip portion 301 is inserted into the gelatin film layer 203, and the gelatin film layer 203 is provided with a stopper portion at the end far from the suture needle 1 for limiting the movement of the suture fixing block 3. The design considers that some hemostatic and anti-inflammatory drugs are released firstly and are used for playing a role directly in the suturing process, the suture fixing block 3 can generate displacement relative to the suture 2 along with the traction of the suture 1 after the first needle is inserted, the suture fixing block slides to the tail end of the suture 2, and in the process, the tip part 301 can cut the gelatin film layer 203 to release the drugs in the suture fixing block. The stopper is provided to limit the position of the suture fixing block 3 at the tail of the suture 2, thereby forming a thread end fixing structure of the suture 2.

The number and specific position of the tip part 301 are not limited, and the tip part 301 can be designed to be different and configured according to the use effect, for example, the tip part 301 is better designed at the upper end of the suture fixing block 3; however, in shape, the tip 301 is inclined to be perpendicular to the suture 2 or to the side of the tail of the suture 2, which is more favorable for dividing the gelatin film layer 203, especially when the lower edge of the tip 301 is perpendicular to the structure itself, the overall structural strength and stability of the tip 301 are the best (as shown in fig. 3). Further, in order to better fix the tail parts of the suture fixing block 3 and the suture 2 into a whole, the two can be fixedly connected, and the specific implementation structure of the connection can be that the upper end surface of the blocking part is in fit connection with the lower end surface of the suture fixing block 3, for example, a clamping assembly, an adhesive assembly and the like are arranged on the fit surface, so as to realize the final locking.

In the embodiment of the present invention, the tip 301 needs to have a certain cutting force and needs to be optimized in terms of hardness, and a specific solution for the optimization may be that the exterior of the tip 301 is further wrapped with a polyester polymer material layer, and the polyester polymer material has higher strength and higher hardness, and has a long absorption time, causes less tissue reaction, and is suitable for enhancing the performance of the tip 301.

The optimized and improved scheme of the embodiment of the invention is that the absorbable hemostatic sponge particles 2011 are made of chitosan hemostatic sponge, so that the chitosan hemostatic sponge has good biocompatibility and can be degraded in a human body, degradation products are safe and non-toxic, and the chitosan hemostatic sponge has an antibacterial and anti-inflammatory effect due to positive charges, and the sponge made of chitosan can still keep the elasticity of the sponge after being wetted, so that the chitosan hemostatic sponge has a good compression hemostasis effect, and has good effects of promoting wound healing, inhibiting the growth of fibroblasts and reducing the formation of scars. When a plurality of absorbable hemostatic sponge particles 2011 are respectively arranged at the boundary line of the two strands of the wire body I2012, a connecting part can be formed at the boundary line, so that the whole body of the wire body core part 201 is combined more tightly, the tension of the wire body core part can be maintained for a long time, a low friction coefficient and good tissue trafficability are obtained, and the superior performance of auxiliary hemostasis is brought into full play.

In another embodiment shown in fig. 5, a suture suitable for the anastomosis of bleeding blood vessels of parenchymal organs comprises a suture 2, and a suture needle 1 and a suture fixing block 3 which are arranged at two ends of the suture 2, wherein the suture 2 comprises a thread core 201, a hemostatic and anti-inflammatory drug interlayer 202 and a gelatin film layer 203 which are circumferentially arranged inside and outside, the thread core 201 is woven by three strands of threads, and the three strands of threads are respectively a thread ii 2012-1 made of absorbable hemostatic sponge, a thread 2012-2 made of polyglycolic acid and a piece of gut 2012-3 (preferably chrome gut which is made by chromic acid treatment and can slow down the tissue absorption speed and cause less inflammatory reaction), and the three strands are tightly twisted together in an upper and lower close manner without limitation in sequence; the suture fixing block 3 is a solid body made of collagen. In the embodiment of the invention, the biggest difference from the previous embodiments is that three different absorbable materials are selected for weaving the wire body core part 201, and the similar technical effect can be achieved, namely, the different absorption time of the three absorbable materials by the tissue is facilitated, the absorbable materials are gradually integrated with the tissue along with the healing of the wound in the time dimension, the more obvious gradient is beneficial to the healing of the needle eye, the adhesiveness is stronger, the probability of wound damage in the later period is reduced, and even when the needle eye bleeding exists, the absorbable hemostatic sponge can be used for hemostasis to a certain extent.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, and all simple modifications and equivalent variations of the above embodiment according to the technical spirit of the present invention are included in the protection scope of the present invention.

Claims

1. The utility model provides a suture line suitable for anastomosing of parenchymal viscera hemorrhage blood vessel, includes suture (2) and sets up suture needle (1) and suture fixed block (3) at its both ends, characterized by: the suture (2) comprises a line body core part (201) which is circumferentially arranged inside and outside, a hemostatic and anti-inflammatory drug interlayer (202) and a gelatin film layer (203), wherein the line body core part (201) is formed by wrapping absorbable hemostatic sponge particles (2011) with two line bodies I (2012) and weaving, and the two line bodies I (2012) are polyglycolic acid lines; the suture fixing block (3) is a solid body made of collagen.

2. The suture line suitable for the anastomosis of bleeding blood vessels of parenchymal organs, according to claim 1, wherein: the sewing needle (1) and the sewing thread (2) are integrally connected.

3. The suture thread suitable for the anastomosis of bleeding blood vessels of parenchymal organs according to claim 1 or 2, wherein: the external shape of the suture fixing block (3) is cubic or boat anchor shape.

4. The suture line suitable for the anastomosis of bleeding blood vessels of parenchymal organs, according to claim 1, wherein: the novel sewing needle is characterized in that the suture fixing block (3) is slidably mounted on the suture (2), the initial mounting position of the suture fixing block is at one end close to the sewing needle (1), a tip portion (301) is arranged on the inner surface, in contact with the suture (2), of the suture fixing block (3), the front end of the tip portion (301) is inserted into the gelatin film layer (203), and a blocking portion for limiting the movement of the suture fixing block (3) is arranged at the end, far away from the sewing needle (1), of the gelatin film layer (203).

5. The suture line suitable for the anastomosis of bleeding blood vessels of parenchymal organs, according to claim 4, wherein: the upper end surface of the blocking part is matched and connected with the lower end surface of the suture fixing block (3) to realize locking.

6. The suture thread for anastomosis of bleeding blood vessels of parenchymal organs, according to claim 4 or 5, wherein: the outer part of the tip part (301) is also wrapped with a polyester polymer material layer.

7. The suture line suitable for the anastomosis of bleeding blood vessels of parenchymal organs, according to claim 1, wherein: the absorbable hemostatic sponge particles (2011) are made of chitosan hemostatic sponge.

8. The suture thread for anastomosis of bleeding blood vessels of parenchymal organs, according to claim 1 or 7, wherein: a plurality of absorbable hemostatic sponge particles (2011) are respectively arranged at the intersection line of the two strands of the line body I (2012).

9. The utility model provides a suture line suitable for anastomosing of parenchymal viscera hemorrhage blood vessel, includes suture (2) and sets up suture needle (1) and suture fixed block (3) at its both ends, characterized by: the suture (2) comprises a line body core part (201) which is circumferentially arranged inside and outside, a hemostatic and anti-inflammatory drug interlayer (202) and a gelatin film layer (203), wherein the line body core part (201) is formed by weaving three lines, the three lines are respectively a line body II (2012-1) which is made of absorbable hemostatic sponge, a line body III (2012-2) of polyglycolic acid and a piece of intestinal line (2012-3), and the three lines are tightly twisted together from top to bottom; the suture fixing block (3) is a solid body made of collagen.