CN111670476A - 患病风险预测方法、电子设备及存储介质 - Google Patents
患病风险预测方法、电子设备及存储介质 Download PDFInfo
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Abstract
本申请公开患病风险预测方法、电子设备及存储介质，所述方法包括：获得被检测对象的属于预定基因组的突变基因对于若干条预定信号通路的活性改变的驱动力信息；获得第一及第二参考对象组中的每个参考对象的属于所述预定基因组的突变基因对于所述若干条预定信号通路的活性改变的驱动力信息；其中，所述第一参考对象组中的各参考对象属于健康类对象，所述第二参考对象组中的各参考对象属于患特定疾病类对象；依据所述被检测对象的突变基因对于若干条预定信号通路的活性改变的驱动力信息及所述第一及第二参考对象组中的每个参考对象的突变基因对于所述若干条预定信号通路的活性改变的驱动力信息，对所述被检测对象、第一及第二参考对象组中的各参考对象进行第一聚类；以及依据进行所述第一聚类后获得的第一聚类结果输出所述被检测对象患所述特定疾病的风险。
Description
PCT国内申请，说明书已公开。
Claims (16)
- PCT国内申请，权利要求书已公开。
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| Application Number | Priority Date | Filing Date | Title |
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| PCT/CN2018/122786 WO2020124584A1 (zh) | 2018-12-21 | 2018-12-21 | 患病风险预测方法、电子设备及存储介质 |
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| CN111670476A true CN111670476A (zh) | 2020-09-15 |
| CN111670476B CN111670476B (zh) | 2023-04-25 |
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| US (1) | US20220068491A1 (zh) |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110246409A1 (en) * | 2010-04-05 | 2011-10-06 | Indian Statistical Institute | Data set dimensionality reduction processes and machines |
| CN103180462A (zh) * | 2010-10-06 | 2013-06-26 | 拜奥默里克斯公司 | 确定生物通路活性的方法 |
| US20170218456A1 (en) * | 2014-07-23 | 2017-08-03 | Ontario Institute For Cancer Research | Systems, Devices and Methods for Constructing and Using a Biomarker |
| CN107658023A (zh) * | 2017-09-25 | 2018-02-02 | 泰康保险集团股份有限公司 | 疾病预测方法、装置、介质和电子设备 |
| CN107924430A (zh) * | 2015-08-17 | 2018-04-17 | 皇家飞利浦有限公司 | 生物数据模式识别的多级体系构架 |
| CN109036571A (zh) * | 2014-12-08 | 2018-12-18 | 20/20基因系统股份有限公司 | 用于预测患有癌症的可能性或风险的方法和机器学习系统 |
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2018
- 2018-12-21 CN CN201880003024.9A patent/CN111670476B/zh active Active
- 2018-12-21 WO PCT/CN2018/122786 patent/WO2020124584A1/zh active Application Filing
- 2018-12-21 US US17/416,919 patent/US20220068491A1/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110246409A1 (en) * | 2010-04-05 | 2011-10-06 | Indian Statistical Institute | Data set dimensionality reduction processes and machines |
| CN103180462A (zh) * | 2010-10-06 | 2013-06-26 | 拜奥默里克斯公司 | 确定生物通路活性的方法 |
| US20170218456A1 (en) * | 2014-07-23 | 2017-08-03 | Ontario Institute For Cancer Research | Systems, Devices and Methods for Constructing and Using a Biomarker |
| CN109036571A (zh) * | 2014-12-08 | 2018-12-18 | 20/20基因系统股份有限公司 | 用于预测患有癌症的可能性或风险的方法和机器学习系统 |
| CN107924430A (zh) * | 2015-08-17 | 2018-04-17 | 皇家飞利浦有限公司 | 生物数据模式识别的多级体系构架 |
| CN107658023A (zh) * | 2017-09-25 | 2018-02-02 | 泰康保险集团股份有限公司 | 疾病预测方法、装置、介质和电子设备 |
Non-Patent Citations (3)
| Title |
|---|
| DELILA GASI TANDEFELT等: "A 36-gene Signature Predicts Clinical Progression in a Subgroup of ERG-positive Prostate Cancers" * |
| P.SINN等: "Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility" * |
| 王博龙: "基于网络药理学的枳术汤活性成分-靶点-通路研究" * |
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| Publication number | Publication date |
|---|---|
| WO2020124584A1 (zh) | 2020-06-25 |
| CN111670476B (zh) | 2023-04-25 |
| US20220068491A1 (en) | 2022-03-03 |
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Application publication date: 20200915 Assignee: Beijing Fangyuan Zhihui Technology Co.,Ltd. Assignor: PHIL RIVERS TECHNOLOGY, Ltd. Contract record no.: X2024980000485 Denomination of invention: Disease risk prediction methods, electronic devices, and storage media Granted publication date: 20230425 License type: Exclusive License Record date: 20240116 |
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