CN111659020A - Diagnostic device for brain glioma - Google Patents

Diagnostic device for brain glioma Download PDF

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Publication number
CN111659020A
CN111659020A CN202010531328.1A CN202010531328A CN111659020A CN 111659020 A CN111659020 A CN 111659020A CN 202010531328 A CN202010531328 A CN 202010531328A CN 111659020 A CN111659020 A CN 111659020A
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CN
China
Prior art keywords
catheter
disc
implantation
photodynamic
brain glioma
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Pending
Application number
CN202010531328.1A
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Chinese (zh)
Inventor
丁陈禹
康德智
林章雅
林元相
吴赞艺
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First Affiliated Hospital of Fujian Medical University
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First Affiliated Hospital of Fujian Medical University
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Application filed by First Affiliated Hospital of Fujian Medical University filed Critical First Affiliated Hospital of Fujian Medical University
Priority to CN202010531328.1A priority Critical patent/CN111659020A/en
Publication of CN111659020A publication Critical patent/CN111659020A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/063Radiation therapy using light comprising light transmitting means, e.g. optical fibres

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses a diagnosis device for brain glioma, which comprises a photodynamic irradiation catheter and an implantation catheter which are matched with each other, wherein a catheter plug is arranged at the top end of the implantation catheter, and a plurality of sealing mechanisms are uniformly arranged in the implantation catheter. This scheme is through the inside structure to implanting the pipe and with the sealed improvement of pipe stopper, can avoid when implanting the pipe and insert the tumour intracavity, liquid such as its inside gathering blood guarantees that photodynamic shines the pipe and after inserting the implantation pipe, and the imaging member of its bottom can acquire clear picture, makes things convenient for smooth going on of photodynamic treatment, can prevent liquid overflow simultaneously and implant the pipe, avoids infecting.

Description

Diagnostic device for brain glioma
Technical Field
The invention relates to the technical field of medical instruments, in particular to a diagnosis device for brain glioma.
Background
Brain gliomas are the most common primary malignant brain tumors of brain and spinal cord glial cell origin. The treatment method aiming at the brain glioma generally comprises surgical resection, postoperative chemotherapy and radiotherapy. However, brain gliomas, especially high-grade gliomas, inevitably develop recurrence with extremely poor prognosis. Therefore, there is a need for a diagnostic technique that can be applied multiple times after surgery with less trauma to the patient to treat recurrent brain glioma conditions.
The principle of photodynamic therapy is that a specific photosensitizer is injected into a human body, and the photosensitizer can be specifically enriched in tumor tissues within a certain time window, and then a light source with a specific wavelength is used for irradiation, so that a photosensitizing chemical reaction can be generated, a biological toxic substance can be generated, and the tumor tissues can be killed.
Through retrieval, the Chinese patent No. CN209679320U discloses a brain glioma photodynamic diagnosis and treatment device, which comprises a photodynamic irradiation catheter and an implantation catheter which are mutually matched for use, wherein the photodynamic irradiation catheter comprises an irradiation catheter tube body, and a photodynamic irradiation optical fiber is arranged in the irradiation catheter tube body; one end of the photodynamic irradiation optical fiber is positioned on the lower end surface of the irradiation catheter body, and the other end of the photodynamic irradiation optical fiber is connected with a photodynamic interface; the irradiation end of the irradiation catheter body is also provided with an imaging component; and the irradiation end of the irradiation catheter body is also provided with an illumination light source.
The diagnosis and treatment device in the prior art still has the following defects in actual use: when the implantation catheter is inserted into the tumor cavity, various liquids such as blood and the like in the tumor cavity can enter the implantation catheter to cause the liquid to be butted in the implantation catheter, so that when the photodynamic irradiation catheter is inserted into the implantation catheter, an imaging part in the photodynamic irradiation catheter cannot obtain a clear picture, the later treatment observation is influenced, and great inconvenience is brought to the photodynamic treatment; in addition, the connection of the implanted catheter to the catheter plug is unstable, particularly when the patient interacts, and fluids collected in the implanted catheter are prone to overflow, increasing the risk of infection, and improvements are needed.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a diagnostic device for brain glioma.
In order to achieve the purpose, the invention adopts the following technical scheme:
the diagnosis device for the brain glioma comprises a photodynamic irradiation catheter and an implantation catheter which are matched with each other, wherein a catheter plug is installed at the top end of the implantation catheter, and a plurality of sealing mechanisms are uniformly arranged in the implantation catheter.
Furthermore, each sealing mechanism comprises a ring body and a closed circular sheet, the ring body is located on the upper side of the closed circular sheet, the inner diameter of the ring body is smaller than that of the closed circular sheet, the outer diameter of the ring body is the same as that of the closed circular sheet and that of the implantation catheter, the outer edge of the ring body is fixed to the inner wall of the implantation catheter, and one side of the edge of the closed circular sheet is fixed to the inner wall of the implantation catheter.
Further, the ring body and the closed circular sheet are both made of silica gel or polyurethane materials.
Furthermore, the bottom of the catheter plug is connected with the inner wall of the top end of the implanted catheter in a sealing mode through a silica gel ring.
Further, every sealing mechanism all includes second opening disk and second opening disk, second opening disk and second opening disk laminate each other, the outer border of second opening disk and the outer border of second opening disk all are fixed with the inner wall of implanting the pipe, the second opening disk runs through and has seted up the cross opening, the second opening disk runs through and has seted up X shape opening, the cross opening does not coincide with X shape opening.
Furthermore, the cross-shaped opening is formed to the edge of the second opening wafer, and the X-shaped opening is formed to the edge of the second opening wafer.
Further, the second opening wafer and the second opening wafer are both made of silica gel or polyurethane materials.
Further, the bottom of the catheter plug is connected with the inner wall of the top end of the implantation catheter in a sealing mode through threads.
Compared with the prior art, the invention has the beneficial effects that:
this scheme is through the inside structure to implanting the pipe and with the sealed improvement of pipe stopper, can avoid when implanting the pipe and insert the tumour intracavity, liquid such as its inside gathering blood guarantees that photodynamic shines the pipe and after inserting the implantation pipe, and the imaging member of its bottom can acquire clear picture, makes things convenient for smooth going on of photodynamic treatment, can prevent liquid overflow simultaneously and implant the pipe, avoids infecting.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
Fig. 1 is a schematic overall structure diagram of a diagnostic device for brain glioma according to the present invention;
FIG. 2 is an overall block and sectional view of a first embodiment of an implanted catheter and catheter plug of the present invention;
FIG. 3 is a schematic, exploded view of the sealing mechanism of FIG. 2;
FIG. 4 is an overall block and sectional view of a second embodiment of an implant catheter and catheter plug of the present invention;
fig. 5 is a schematic structural disassembly diagram of the sealing mechanism in fig. 4.
In the figure: 1 photodynamic irradiation catheter, 2 implantation catheter, 3 catheter plug, 4 sealing mechanism, 5 silica gel ring, 6 screw thread, 41 ring body, 42 closed wafer, 411 second opening wafer, 421 second opening wafer, 4111 cross-shaped opening and 4211X-shaped opening.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example one
Referring to fig. 1-3, a diagnosis device for brain glioma comprises a photodynamic irradiation catheter 1 and an implantation catheter 2 which are used in cooperation with each other, a catheter plug 3 is installed at the top end of the implantation catheter 2, and a plurality of sealing mechanisms 4 are uniformly arranged inside the implantation catheter 2.
Further, each sealing mechanism 4 comprises a ring body 41 and a closed circular sheet 42, the ring body 41 is positioned on the upper side of the closed circular sheet 42, the inner diameter of the ring body 41 is smaller than the diameter of the closed circular sheet 42, the outer diameter of the ring body 41 is the same as the diameter of the closed circular sheet 42 and the inner diameter of the implantation catheter 2, the outer edge of the ring body 41 is fixed with the inner wall of the implantation catheter 2, and one side of the edge of the closed circular sheet 42 is fixed with the inner wall of the implantation catheter 2.
Further, the ring body 41 and the closed circular disc 42 are both made of silicone or polyurethane material.
Further, the bottom of the catheter plug 3 is connected with the inner wall of the top end of the implantation catheter 2 in a sealing mode through a silica gel ring 5.
In the embodiment, the catheter plug 3 is hermetically connected with the implantation catheter 2 through the silica gel ring 5 (the inner wall of the top end of the implantation catheter 2 is provided with the sealing groove matched with the silica gel ring 5), the implantation catheter 2 is inserted into the tumor cavity, and the sealing mechanism 4 implanted in the implantation catheter 2 can perform multiple sealing on the inside of the implantation catheter 2 through the arrangement of the ring body 41 and the closed wafer 42, so that liquid in the tumor cavity is prevented from entering the implantation catheter 2; when in diagnosis and treatment, the catheter plug 3 is taken down, the bottom end of the photodynamic irradiation catheter 1 can be inserted into the implantation catheter 2, the bottom end of the photodynamic irradiation catheter 1 can form downward extrusion force on the ring body 41 and the closed circular sheet 42 in the sealing mechanism 4, so that one side of each ring body 41 is sequentially forced to be away from the closed circular sheet 42 to turn downwards, the bottom end of the photodynamic irradiation catheter 1 can enter a tumor cavity, and then the photodynamic diagnosis and treatment can be carried out according to the steps just opened in the Chinese patent No. CN 209679320U.
Example two
Referring to fig. 1, 4 and 5, a diagnosis device for brain glioma comprises a photodynamic irradiation catheter 1 and an implantation catheter 2 which are used in cooperation, a catheter plug 3 is installed at the top end of the implantation catheter 2, and a plurality of sealing mechanisms 4 are uniformly arranged inside the implantation catheter 2.
Further, each sealing mechanism 4 includes a second opening disc 411 and a second opening disc 421, the second opening disc 411 and the second opening disc 421 are attached to each other, the outer edge of the second opening disc 411 and the outer edge of the second opening disc 421 are both fixed to the inner wall of the implanted catheter 2, the second opening disc 411 is provided with a cross-shaped opening 4111 in a penetrating manner, the second opening disc 421 is provided with an X-shaped opening 4211 in a penetrating manner, and the cross-shaped opening 4111 is not overlapped with the X-shaped opening 4211.
Further, the cross-shaped opening 4111 opens to the edge of the second opening disc 411, and the X-shaped opening 4211 opens to the edge of the second opening disc 421.
Further, the second open disc 411 and the second open disc 421 are both made of silicone or polyurethane material.
Further, the bottom of the catheter plug 3 is sealingly connected to the inner wall of the top end of the implantation catheter 2 by means of a thread 6.
The photodynamic irradiation catheter has the same structure and function as the photodynamic irradiation catheter in the Chinese patent No. CN209679320U document, namely, the photodynamic irradiation catheter comprises an irradiation catheter body, the upper part of the irradiation catheter body is provided with a handle, the movable bending part is of a fin tube structure, the upper end of an illumination optical fiber is respectively connected with a photodynamic interface and an illumination interface, the illumination interface is connected with a medical illumination light source, the photodynamic interface is connected with a clinical photodynamic light source, an imaging component is an image transmission optical fiber or a miniature electronic imaging element, and the imaging component is also arranged on the lower end face of the irradiation catheter body and is connected with an external display device through a video interface.
In this embodiment, the catheter plug 3 is hermetically connected with the implantation catheter 2 through the thread 6, the implantation catheter 2 is inserted into the tumor cavity, and the sealing mechanism 4 implanted in the catheter 2 can perform multiple sealing on the inside of the implantation catheter 2 through the arrangement of the second opening disc 411 and the second opening disc 421, so as to prevent liquid in the tumor cavity from entering the implantation catheter 2; when in diagnosis and treatment, the catheter plug 3 is taken down, the bottom end of the photodynamic irradiation catheter 1 can be inserted into the implantation catheter 2, the bottom end of the photodynamic irradiation catheter 1 can form downward extrusion force on the second opening disc 411 and the second opening disc 421 in the sealing mechanism 4, the bottom end of the photodynamic irradiation catheter 1 can pass through the second opening disc 411 and the second opening disc 421 through each cross-shaped opening 4111 and the X-shaped opening 4211 to move downwards so as to enter a tumor cavity, and then photodynamic diagnosis and treatment can be carried out according to the steps just opened in the Chinese patent No. CN 209679320U.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (8)

1. The diagnosis device for the brain glioma comprises a photodynamic irradiation catheter (1) and an implantation catheter (2) which are matched with each other, and is characterized in that a catheter plug (3) is installed at the top end of the implantation catheter (2), and a plurality of sealing mechanisms (4) are uniformly arranged in the implantation catheter (2).
2. The diagnostic device for brain glioma according to claim 1, wherein each sealing means (4) comprises a ring body (41) and a closed disc (42), wherein the ring body (41) is located on the upper side of the closed disc (42), the inner diameter of the ring body (41) is smaller than the diameter of the closed disc (42), the outer diameter of the ring body (41) is the same as the diameter of the closed disc (42) and the inner diameter of the implantation catheter (2), the outer edge of the ring body (41) is fixed to the inner wall of the implantation catheter (2), and one side of the edge of the closed disc (42) is fixed to the inner wall of the implantation catheter (2).
3. The diagnostic device for brain glioma according to claim 2, wherein the ring body (41) and the closed disc (42) are both made of silicone or polyurethane material.
4. A diagnostic device for brain glioma according to claim 1 characterized in that the bottom of the catheter plug (3) is sealingly connected to the inner wall of the tip of the implanted catheter (2) by a silicone ring (5).
5. A diagnostic device for brain glioma according to claim 1, wherein each sealing means (4) comprises a second open disc (411) and a second open disc (421), the second open disc (411) and the second open disc (421) are attached to each other, the outer edge of the second open disc (411) and the outer edge of the second open disc (421) are fixed to the inner wall of the implanted catheter (2), the second open disc (411) has a cross-shaped opening (4111) formed therethrough, the second open disc (421) has an X-shaped opening (4211) formed therethrough, and the cross-shaped opening (4111) is not overlapped with the X-shaped opening (4211).
6. A diagnostic device for brain glioma according to claim 5 wherein the cross-shaped opening (4111) opens up to the edge of the second open disc (411) and the X-shaped opening (4211) opens up to the edge of the second open disc (421).
7. The diagnostic device for brain glioma according to claim 5, wherein the second open disc (411) and the second open disc (421) are both made of silicone or polyurethane material.
8. A diagnostic device for brain glioma according to claim 1 wherein the bottom of the catheter plug (3) is sealingly connected to the inner wall of the top end of the implanted catheter (2) by a thread (6).
CN202010531328.1A 2020-06-11 2020-06-11 Diagnostic device for brain glioma Pending CN111659020A (en)

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Application Number Priority Date Filing Date Title
CN202010531328.1A CN111659020A (en) 2020-06-11 2020-06-11 Diagnostic device for brain glioma

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Application Number Priority Date Filing Date Title
CN202010531328.1A CN111659020A (en) 2020-06-11 2020-06-11 Diagnostic device for brain glioma

Publications (1)

Publication Number Publication Date
CN111659020A true CN111659020A (en) 2020-09-15

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Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147332A (en) * 1991-05-17 1992-09-15 C.R. Bard, Inc. Multi-valve catheter for improved reliability
CN2248569Y (en) * 1996-04-16 1997-03-05 粟祜 Device for introducing media into the body by inserting skin of anti-back-flow type
CN2511314Y (en) * 2001-05-30 2002-09-18 钱云周 One way joint of injection for infusion pump
CN1437491A (en) * 1999-12-27 2003-08-20 阿尔萨公司 Osmotic beneficial agent delivery system
CN103016428A (en) * 2013-01-06 2013-04-03 辽宁省电力有限公司铁岭供电公司 Air bleeder for accumulator
CN103877675A (en) * 2014-02-21 2014-06-25 牛洪欣 Intracavity radioactive-particle implant
CN205134500U (en) * 2015-11-23 2016-04-06 张文才 Deodorant valve launchs
CN108042899A (en) * 2018-01-24 2018-05-18 山东百多安医疗器械有限公司 A kind of dual valve implantable drug delivery system
CN207462454U (en) * 2017-04-12 2018-06-08 牛洪欣 Rechargeable type particle conduit
CN109758674A (en) * 2019-01-23 2019-05-17 武汉布润脑医学科技有限责任公司 A kind of glioma diagnosing and treating apparatus
CN209771078U (en) * 2018-12-17 2019-12-13 深圳市擎源医疗器械有限公司 drug delivery device

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147332A (en) * 1991-05-17 1992-09-15 C.R. Bard, Inc. Multi-valve catheter for improved reliability
CN2248569Y (en) * 1996-04-16 1997-03-05 粟祜 Device for introducing media into the body by inserting skin of anti-back-flow type
CN1437491A (en) * 1999-12-27 2003-08-20 阿尔萨公司 Osmotic beneficial agent delivery system
CN2511314Y (en) * 2001-05-30 2002-09-18 钱云周 One way joint of injection for infusion pump
CN103016428A (en) * 2013-01-06 2013-04-03 辽宁省电力有限公司铁岭供电公司 Air bleeder for accumulator
CN103877675A (en) * 2014-02-21 2014-06-25 牛洪欣 Intracavity radioactive-particle implant
CN205134500U (en) * 2015-11-23 2016-04-06 张文才 Deodorant valve launchs
CN207462454U (en) * 2017-04-12 2018-06-08 牛洪欣 Rechargeable type particle conduit
CN108042899A (en) * 2018-01-24 2018-05-18 山东百多安医疗器械有限公司 A kind of dual valve implantable drug delivery system
CN209771078U (en) * 2018-12-17 2019-12-13 深圳市擎源医疗器械有限公司 drug delivery device
CN109758674A (en) * 2019-01-23 2019-05-17 武汉布润脑医学科技有限责任公司 A kind of glioma diagnosing and treating apparatus

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Application publication date: 20200915