CN111657296A

CN111657296A - Weeding composition containing glufosinate-ammonium

Info

Publication number: CN111657296A
Application number: CN202010570838.XA
Authority: CN
Inventors: 李玉洁; 李冰清
Original assignee: Hefei Keao Biotechnology Co ltd
Current assignee: Hefei Keao Biotechnology Co ltd
Priority date: 2020-06-19
Filing date: 2020-06-19
Publication date: 2020-09-15

Abstract

The invention relates to a weeding composition specially used for citrus orchard and non-cultivated land, which at least comprises three components of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin, and the mass ratio of active ingredients is (1-50): (1-50): (1-50), preferably (1-10): (1-10): (1-10). The preparation formulation of the weeding composition which can be prepared by a method known by a person skilled in the art comprises an aqueous solution, a suspending agent, a suspoemulsion, a dispersible oil suspending agent, a wettable powder, a water dispersible granule, a granule and a microcapsule suspension-suspending agent, wherein the weight percentage content of active ingredients in the preparation is 1-80%, and the preferable weight percentage content is 5-75%. The invention also relates to application of the composition in preventing and removing weeds in citrus orchard and non-cultivated land.

Description

Weeding composition containing glufosinate-ammonium

Technical Field

The invention relates to a weeding composition, which consists of active ingredients of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin, and belongs to the technical field of compound pesticide compounding.

Background

Flumioxazin, the english generic name flumioxazin, chemical name: 7-fluoro-6- (3,4,5, 6-tetrahydro) phthalimido-4- (2-propynyl) -1, 4-benzoxazine-3 (2H) -ketone, which belongs to a cyclic imine herbicide in structure. The flumioxazin is a herbicide absorbed by buds and leaves, can effectively prevent and kill 1-year-old broadleaf weeds and part of gramineous weeds when being used for soil treatment, is easy to degrade in the environment, and is safe for succeeding crops. The soybean and the peanut have good drug resistance. Maize, wheat, barley, rice have moderate tolerance.

Fluoroglycofen-ethyl, english generic name Fluoroglycofen, chemical name: ethyl 0- [5- (2-chloro-a, a, a-trifluoro-p-tolyloxy) -2-nitrobenzoyl ] glycolate, structurally belonging to a diphenyl ether herbicide and mechanism of action belonging to protoporphyrin oxidase inhibitor. The herbicide is used for preventing and killing most of broadleaf weeds in soybean fields, and although the herbicide has certain activity to sensitive dicotyledonous weeds when applied before emergence, the dosage of the herbicide is 2-10 times higher than that of the herbicide after emergence. The agent is not effective in controlling narrow-leaf or perennial weeds. Is suitable for weeding wheat, barley, peanut, soybean and paddy fields. Can prevent and kill off broad-leaved weeds, in particular weeds of cleavers, speedwell, viola, xanthium and sweet potatoes.

Glufosinate ammonium, the english generic name Glufosinate ammonium, chemical name: ammonium 2-amino-4- [ hydroxy (methyl) phosphonyl ] butyrate, structurally belongs to an organophosphorus herbicide, has a mechanism of action of a glutamine synthesis inhibitor and is a non-selective contact herbicide. Has a certain systemic effect, can be used for weeding in orchards, vineyards and uncultivated areas, and can also be used for preventing and removing annual or perennial dicotyledons, gramineous weeds, nutgrass flatsedge and the like in potato fields.

At present, the special development of the herbicide for citrus orchard and non-cultivated land is less in the market, so that the development of the mixed herbicide which is more special for preventing and killing common weeds in the citrus orchard and the non-cultivated land is very necessary.

Disclosure of Invention

The invention aims to provide a weeding composition specially used for citrus orchard and non-cultivated land, which at least comprises three components of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin.

The invention also aims to provide the application of the composition in preventing and removing the weeds in citrus orchard and non-cultivated land.

In order to overcome the defect of single preparation or binary combination in the prior art, the technical scheme of the weeding composition is as follows:

A) a first active ingredient, glufosinate;

B) a second active ingredient fluoroglycofen-ethyl;

C) the third active component flumioxazin.

The mass ratio of the first active ingredient to the second active ingredient to the third active ingredient is (1-50): (1-50): (1-50), preferably (1-10): (1-10): (1-10).

The weeding composition containing glufosinate-ammonium can be prepared into preparations such as aqueous solution, suspending agent, suspoemulsion, dispersible oil suspending agent, wettable powder, water dispersible granule, granule and microcapsule suspension-suspending agent according to a method known by a person skilled in the art, and the weight percentage of active ingredients in the preparation is 1-80%, preferably 5-75%.

For aqueous agents, optional adjuvants include: emulsifiers such as calcium dodecylbenzene sulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, agricultural emulsion 2201#, sorbitan monostearate polyoxyethylene ether, nonylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, phenethylphenol polyoxyethylene polyoxypropylene ether, agricultural emulsion 600#, agricultural emulsion 400#, dodecyl dimethyl benzyl ammonium chloride and the like; the solvent water is deionized water.

For suspending agents, optional adjuvants include: dispersing agents such as one or more of polycarboxylate, lignosulfonate, alkylnaphthalene formaldehyde condensate sulfonate, alkylphenol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether sulfonate, phenethyl phenol polyoxyethylene ether phosphate, alkyl polyoxyethylene ether sulfonate, polyoxyethylene polyoxypropylene ether block copolymer, nekal, dodecyl polyoxyethylene ether phosphate, etc.; wetting agents such as one or more of alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, phenethylphenol polyoxyethylene ether phosphate ester, alkylsulfate, alkylsulfonate, alkylnaphthalenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, tristyrylphenol polyoxypropylene polyoxyethylene block polymer, and the like; thickening agents such as one or more of xanthan gum, polyvinyl alcohol, bentonite, magnesium aluminum silicate, carboxymethyl cellulose, carboxyethyl cellulose, methyl cellulose, and the like; preservatives such as one or more of formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, isothiazolinone, and the like; defoaming agents such as one or more of silicone oil, silicone compounds, C10-20 saturated fatty acid compounds, C8-10 fatty alcohols, hexanol, butanol, octanol, etc.; antifreeze agents such as one or more of ethylene glycol, propylene glycol, glycerol, polyethylene glycol, sorbitol, urea, inorganic salts, etc.; the water is deionized water.

For suspoemulsions, optional adjuvants include: emulsifier such as one or more of calcium dodecylbenzene sulfonate (Nongru 500#), Nongru 700#, Nongru 2201, span-60 #, emulsifier T-60 (common name: sorbitan monostearate polyoxyethylene ether), TX-10 (common name: octylphenol polyoxyethylene (10) ether), Nongru 1601#, Nongru 600#, Nongru 400#, etc.; dispersants such as one or more of polycarboxylates, lignosulfonates, alkylnaphthalenesulfonates, and the like; solvents such as one or more of dimethyl phthalate, dibutyl phthalate, ethyl acetate, methyl benzoate, and the like; defoaming agents such as one or more of silicone oil, silicone compounds, C10-20 saturated fatty acid compounds, C8-10 fatty alcohols, hexanol, butanol, octanol, etc.; thickening agent such as one or more of white carbon black, polyvinyl alcohol, bentonite, magnesium aluminum silicate, etc.; one or more of antifreeze such as ethylene glycol, propylene glycol, glycerol, urea, inorganic salts such as sodium chloride, etc.; the water is deionized water.

For dispersible oil suspensions, optional adjuvants include: dispersants such as one or more of polycarboxylate, alkylnaphthalene sulfonate, TERSPERSE2425 (alkylnaphthalene sulfonate, available from henseme, usa); emulsifier such as one or more of Nongru 700# (common name: alkylphenol formaldehyde polyoxyethylene ether), Nongru 2201, span-60 (common name: sorbitan monostearate), Tween-60 (common name: sorbitan fatty acid ester polyoxyethylene ether), Nongru 1601# (common name: triphenylethylphenol polyoxypropylene polyoxyethylene block polymer), TERSPERSE4894 (Hensmei corporation, USA), TERSPERSE2500 (Hensmei corporation, USA); wetting agents such as one or more of alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethylphenol polyoxyethylene ether phosphate, alkyl sulfate, alkyl sulfonate, naphthalene sulfonate, TERSPERSE2500 (available from henseme, usa); thickening agent such as one or more of white carbon black, polyvinyl alcohol, bentonite, and magnesium aluminum silicate; one or more of antifreeze such as ethylene glycol, propylene glycol, glycerol, urea, inorganic salts such as sodium chloride; dispersing medium such as one or more of soybean oil, oleum Rapae, oleum Maydis, methyl oleate, and oleum ricini.

For wettable powders, optional adjuvants include: dispersing agents such as one or more of polycarboxylate, lignosulfonate, polyoxyethylene polyoxypropylene ether block copolymer, alkyl naphthalene formaldehyde condensate sulfonate, alkylphenol polyoxyethylene ether phosphate, fatty alcohol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether sulfonate and the like; wetting agents such as one or more of alkyl sulfates, alkyl sulfonates, alkyl naphthalene sulfonates, and the like; the filler is one or more of ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon black, light calcium carbonate, talcum powder, attapulgite, pottery clay and the like.

For water dispersible granules, optional auxiliaries include: dispersants such as one or more of polycarboxylates (TERSPERSE2700, T36, GY-D06, etc.), lignosulfonates, alkylnaphthalene sulfonates, and the like; wetting agents such as one or more of alkyl sulfates, alkyl sulfonates, naphthalene sulfonates, and the like; disintegrating agent such as one or more of ammonium sulfate, sodium sulfate, polyvinylpyrrolidone, starch and its derivatives, bentonite, etc.; binder such as one or more of starch, glucose, polyvinyl alcohol, polyethylene glycol, sodium carboxymethylcellulose, sucrose, etc.; the filler is one or more of diatomite, kaolin, white carbon black, light calcium carbonate, talcum powder, attapulgite, pottery clay and the like.

For granules, optional adjuvants include: carriers such as one or more of clay, kaolin, talc, calcium carbonate, corn starch, aluminum silicate, and the like; dispersants such as one or more of polycarboxylates, lignosulfonates, alkylnaphthalenesulfonates, and the like; wetting agents such as one or more of alkyl sulfates, alkyl sulfonates, naphthalene sulfonates, and the like; binder such as one or more of polyvinyl alcohol, dextrin, polyvinylpyrrolidone, etc.

For microcapsule suspension-suspending agents, optional adjuvants include: disintegrating agent such as one or more of bentonite, urea, ammonium sulfate, polyvinylpyrrolidone, glucose, and sodium bicarbonate; preservatives such as one or more of formaldehyde, benzoic acid, sodium benzoate, potassium sorbate, isothiazolinone, and the like; emulsifier such as fatty alcohol polyoxyethylene ether, fatty acid polyoxyethylene ether, calcium dodecylbenzene sulfonate, alkylphenol polyoxyethylene ether, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, sorbitan monostearate polyoxyethylene ether, fatty acid polyoxyethylene ether phosphate, etc.; dispersing agents such as one or more of polycarboxylates, lignosulfonates, alkylphenol polyoxyethylene ether formaldehyde condensate Sulfates (SOPA), naphthalene and alkylnaphthalene formaldehyde condensate sulfonates, EO-PO block polyethers, alkylphenol polyoxyethylene ether phosphates, alkylphenol polyoxyethylene ethers, fatty acid polyoxyethylene esters, fatty amine polyoxyethylene ethers, glycerol fatty acid ester polyoxyethylene ethers, and the like; wetting agents such as one or more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrant F, naphthalene sulfonate formaldehyde condensate and the like; antifreeze agents such as one or more of urea, ethylene glycol, propylene glycol, glycerol, etc.; thickening agents such as one or more of xanthan gum, carboxymethyl cellulose, carboxyethyl cellulose, methyl cellulose, magnesium aluminum silicate, polyvinyl alcohol, and the like; the defoaming agent is one or more of silicone oil, silicone compound, C10-20 saturated fatty acid compound, C8-10 fatty alcohol, ester ether, etc.

The above-mentioned optional adjuvants may be selected by those skilled in the art according to the descriptions in the literature such as "solid preparation", "liquid preparation", and "adjuvant for agricultural chemicals", but the selection of the particular adjuvant needs to be tried by a specific formulation process test, and the optional adjuvants do not always give a uniform and stable formulation.

The invention has reasonable components, good weeding effect in citrus orchard and non-cultivated land, small dosage and low cost, and the activity and the weeding effect of the invention are not simple superposition of the activities of the components, but have obvious synergistic effect, good safety to crops and accordance with the safety requirement of pesticide preparations.

Detailed Description

The effect of ternary combination of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin on preventing and removing common weeds in citrus orchard and non-cultivated land is verified by combined action determination.

Indoor toxicity assay

The test method refers to part 4 of agricultural chemical indoor bioassay test criteria herbicide of agricultural industry standard NY/T1155.4-2006 of the people's republic of China: activity determination test stem leaf spray method and part 7 of agricultural chemical indoor bioassay test criteria herbicide standard NY/T1155.7-2006 of the people's republic of China: combined action assay of compounding. The test subjects were chenopodium glaucum and large crabgrass.

The original drug is prepared into the required test drug, and 6 different concentration gradients are set for each single drug and each compound drug (on the basis of the preliminary test result, the concentration gradients are set differently according to different drug proportions, and the control rate is set according to the geometric progression in the range of 5% -90%). Repeat 4 times with clear water control. The weeds are in the two-leaf or two-leaf one-heart period, and are sprayed from low dose to high dose respectively. After treatment, the mixture is placed in a greenhouse for culture and observation, and water is supplemented in a mode of infiltrating irrigation at the bottom of the pot.

Adopting DPS data processing software to process the test data, and converting according to the liquid spraying amount and the rotary disc area of the Prite spray tower to obtain ED of each medicament for different targets₅₀The value (g/ha). Evaluating the combined action of the mixture by adopting a Sun Yunpei cotoxicity coefficient method, wherein when the CTC is more than 120, the mixture has a synergistic effect, antagonism is achieved when the CTC is less than 120, and addition effect is achieved between the CTC and the CTC.

TABLE 1 Combined action of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin in combination with chenopodium glaucum

TABLE 2 Combined action of glufosinate, fluoroglycofen-ethyl and flumioxazin on large crabgrass

Treatment of	ED₅₀Value (g/ha)	Co-toxicity coefficient
			Glufosinate-ammonium (a)	13.63
Fluoroglycofen-ethyl (b)	14.77
			Flumioxazin (c)	81.73
a:b:c＝1:1:1	15.33	122.99
			a:b:c＝1:3:5	21.68	120.86
a:b:c＝1:5:3	15.72	125.99
			a:b:c＝1:3:1	13.26	128.03
a:b:c＝5:1:1	11.63	126.50
			a:b:c＝5:1:10	22.58	120.93
a:b:c＝1:5:10	23.46	126.29
			a:b:c＝1:10:1	12.26	127.37
CK	-	-

Indoor toxicity test results show that: glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin according to (1-5): (1-10): (1-10) the composition has high activity on chenopodium glaucum and large crabgrass, and can obtain synergistic control effect after the three are combined.

Formulation examples

To better illustrate the invention, the following description of the invention is given in conjunction with formulation examples, the percentages in the formulation being given by weight.

Example 1

Weighing 3% of glufosinate-ammonium, 9% of fluoroglycofen-ethyl, 15% of flumioxazin, 6% of sorbitan monostearate, 5% of polyoxyethylene fatty acid ester, 1% of polyvinyl alcohol, 0.5% of glycol, 2% of penetrating agent JFC, 0.5% of sodium benzoate and deionized water to make up the balance. Dissolving flumioxazin in cyclohexanone, adding sorbitan monostearate, and stirring uniformly to form an oil phase; mixing deionized water and other adjuvants uniformly by high speed shearing homogenizer, adding fluoroglycofen-ethyl, and sanding in a sand mill to make the particle diameter D90 of the suspending agent below 5 μm. Adding the oil phase and glufosinate ammonium crystal into the ground suspending agent, and shearing at high speed to make the particle diameter D90 of the liquid medicine below 5 μm to obtain 27% glufosinate ammonium-fluoroglycofen-propyzamide suspoemulsion.

Example 2

Weighing 10% of glufosinate-ammonium, 30% of fluoroglycofen-ethyl, 10% of flumioxazin, 11% of sorbitan monostearate, 5% of sodium polycarboxylate, 1.3% of magnesium aluminum silicate, 0.4% of potassium sorbate and soybean oil for balancing. The soybean oil and other additives are mixed evenly by a high-speed shearing homogenizer, then the active ingredients are added, and the sand milling is carried out in a sand mill, so that the particle size D90 of the suspending agent is below 5 mu m, and the 50 percent glufosinate-fluoroglycofen-propyzamide dispersible oil suspending agent can be prepared.

Example 3

Weighing 3% of glufosinate-ammonium, 30% of fluoroglycofen-ethyl, 3% of flumioxazin, 5% of alkylphenol polyoxyethylene ether phosphate, 6% of sodium dodecyl sulfate, 3% of ammonium sulfate, 4% of sodium carboxymethylcellulose and white carbon black for balancing. The raw materials are uniformly mixed, crushed by an ultramicro jet mill and uniformly mixed, water is added for kneading granulation, the mixture is dried and screened in a boiling dryer, and the 36 percent glufosinate-fluoroglycofen-propyzamide water dispersible granules can be prepared by detection and analysis.

Test of field drug effect

A field pesticide effect test for preventing and controlling weeds in a preparation example is carried out, and the preventing and controlling effect of the pesticide on weeds and the safety of the pesticide on crops are verified. The test agents and amounts are given in the table below. The total number of the treatments is 6, blank control is additionally arranged, the treatment is repeated for 4 times, each square meter is about 30, the cells are randomly arranged in blocks, and a sector spray head is adopted for spraying, so that the medicament is mainly prevented from contacting crops. And (5) investigating the survival condition of weeds 30d after the application of the herbicide, and calculating the control effect of the weeds and the fresh weight control effect.

The test control objects are as follows: large crabgrass herb and chenopodium glaucum.

TABLE 3 field efficacy test results of different formulations and single doses of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin combination

The results of field experiments show that the preparation examples have good control effect on gramineous weeds and broadleaf weeds and long lasting period, and the average plant control effect and fresh weight control effect of the mixed herbs in 30 days are better than those of a control agent under the condition that the dosage of the effective components is less than that of a single agent.

In the whole growth period, the flumioxazin single agent and the mixed preparation are safe to crops, and do not show the phenomenon of phytotoxicity, which indicates that the pesticide is safe to the crops.

In conclusion, the composition adopts a compounding scheme of three active ingredients, the activity and the weeding effect are not simple superposition of the activities of all the ingredients, and compared with the existing single preparation or binary compound preparation, the composition has the advantages of obvious weeding effect, obvious synergistic effect, capability of delaying resistance, low preparation residue, no pollution to crops, good safety and accordance with the safety requirement of pesticide preparations.

Claims

1. A method for preventing and removing gramineous and broadleaf weeds in citrus orchard and non-cultivated land is characterized in that the method comprises the step of treating the citrus orchard and the non-cultivated land by adopting a compound weeding composition at least comprising glufosinate, fluoroglycofen-ethyl and flumioxazin, wherein the target weeds are in a 3-4 leaf stage, and the mass ratio of the glufosinate to the fluoroglycofen-ethyl to the flumioxazin in the weeding composition is (1-50): (1-50): (1-50).

2. The method according to claim 1, characterized in that the weight ratio of active ingredients in the herbicidal composition is preferably (1-10): (1-10): (1-10).

3. The method as set forth in claim 1 or 2, characterized in that the herbicidal composition can be formulated in the form of aqueous preparations, suspensions, suspoemulsions, dispersible oil suspensions, wettable powders, water dispersible granules, granules and microcapsule suspension-suspensions.

4. The method as claimed in claim 1 or 2, characterized in that the active ingredient in the herbicidal composition is present in an amount of 1% to 80%, preferably 5% to 75% by weight of the formulation.

5. The application of the compound weeding composition in preventing and removing gramineous and broadleaf weeds in citrus orchards and uncultivated areas is characterized in that the mass ratio of glufosinate-ammonium, fluoroglycofen-ethyl and flumioxazin in the weeding composition is (1-10): (1-10): (1-10).

6. A herbicidal composition as claimed in any one of claims 1 to 5.