CN1116516A - Conformable adhesive bandages - Google Patents

Conformable adhesive bandages Download PDF

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Publication number
CN1116516A
CN1116516A CN 95105124 CN95105124A CN1116516A CN 1116516 A CN1116516 A CN 1116516A CN 95105124 CN95105124 CN 95105124 CN 95105124 A CN95105124 A CN 95105124A CN 1116516 A CN1116516 A CN 1116516A
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CN
China
Prior art keywords
binder
product
present
backing material
wound
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Granted
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CN 95105124
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Chinese (zh)
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CN1191799C (en
Inventor
G·B·芬利
M·S·卡塔兰诺
I·戴维斯
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Johnson and Johnson Consumer Inc
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Johnson and Johnson Consumer Products Inc
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Publication of CN1116516A publication Critical patent/CN1116516A/en
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Publication of CN1191799C publication Critical patent/CN1191799C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

This invention relates to a disposable adhesive bandage product that is extremely conformable, yet resilient enough to maintain its shape after being subjected to forces caused by movement of the wearer. Its conformability permits the use of less aggressive and lower weights of adhesive in the manufacture of the bandage.

Description

Conformable adhesive bandages
The present invention relates to be used for little and big skin wound, inflammation and abrasive disposable binder and dressings.More particularly, the present invention relates to extremely softish and can with the disposable binder of wearer's skin attachement.They make the wearer feel comfortable and make binder keep adhering on the skin with smaller adhesion weight and/or less aggressivity binding agent.
For many years, existing many disposable binders that are used for auxiliary treatment wound and damage are sold.They play the effect of covering with the protection wound when wound healing.Disposable binder like this comprises a kind of backing material (this backing material is as substrate and be used for protective ground covering wound), and one places liner and a kind of viscosity composition that is deposited on the backing material on wound or the damage.This viscosity composition adheres to liner on the substrate, and when exposing this substrate is adhered on the skin around wound area.But, have when using such binder several inherent ask ground at first, (as finger, elbow and knee joint) often has scratch in the skin area that the wearer takes regular exercise.This makes binder be subjected to being tending towards making the power of binder distortion.This distortion often makes binder break away from skin.The second, when overcoming this disengaging, make binder with bigger rodent viscosity composition.These materials can stimulate responsive skin and may injure skin on one's body when they are removed with the wearer.
For many years, the concrete instance of the disposable binder product of some commercial uses various changes and improvements have been made.For example, with vinyl film, softish fiber and even foam make backing material, attempt to make the binder that skin and the motion easier and wearer adapt.But, effort does not up to now all provide for consumer and moves to adapt and is bonded at simultaneously binder on the skin tightly.
For example, U.S. Pat, 3025,854 (Scholl, 1962) have illustrated a kind ofly have a film-substrate and a kind of foamy binder, rather than a kind of gauze that is connected on the liner.Yet this structure differs wound is suitably ventilated.
U.S. Pat 3,113,568 (Robins, 1963) a kind of " tourniquet bandage " that comprises an absorbent pad has been described, this binder has the netted obstacle of combining closely, and helps stop the effusive blood of wound with netted obstacle, and the auxiliary clot that forms is to promote healing.This patent proposes such obstacle and can be made of the polyurethane of micropore.
U.S. Pat 3,949,742 (Nowakowski, 1976) have illustrated a kind of medical garment, and this clothes adhesively is fixed to by the transparent thin and lamination polyurethane substrate that softish skim atresia separates on the thin layer of reticulated polymer foam of thrombinogen and constitutes.Substrate layer is answered atresia and as thin as a wafer.
U.S. Pat 4,733,659 (people such as Edenbaum, 1988) relate to a kind of disposable binder of, hydrophilic foam preparation permeable, softish, thermoplastic by monolithic liquid.This foam is with porous, to pressure-sensitive binding agent layering.This foam laminate is then by reduced overall, but will contact except wound that part of.
U.S. Pat 4,730,611 (Lamb, 1988) relate to a kind of dressings that is made of foamed polyurethane liner, and this liner has one and is used for the hydrophilic side that contacts with wound and the hydrophobicity side of a back side wound.Described liner places on the porous non-woven fibre sheet, and this this liner of this fibre plate is big.It has binding agent on lateral that side of contact pad designed hydrophobicity, this makes above-mentioned hydrophobicity side can be used for contacting wound with binding agent.A covering NAG, that can remove places above-mentioned adhesive side, exposes prematurely to prevent liner and binding agent.The shortcoming of this design is to have extremely complicated structure, is not easy for little otch and scratch.
U.S. Pat 4,341,209 (Schaar, 1982) a kind of contact adhesive binder has been described, this binder comprises a low density polyethylene (LDPE) closed porosity foam substrate sheet, and this substrate slice has the surperficial of glossiness, a smooth coarse groove, low friction, no adhesive face and one and has the adherent rear surface of the coating that adheres to a contact adhesive on the absorption pad.Plan substitutes vinyl film with polyethylene, and this thin film comprises plasticizer usually.Plan to make it have the material character same with vinyl.
U.S. Pat, 4,377,159 (Hansen, 1983) have illustrated a kind of pressure bandage with the ssible elastomeric material that is triangle or rectangle, prismatic part basically, and this ssible elastomeric material adheres on the carrier band.This carrier band does not provide additional stickiness.
The hydrogel binder, for example U.S. Pat 5,160, and illustrated hydrogel binder in 328 (people such as Cartmell, 1992) can comprise the polyurethane hydrogel material, but not improve the stickiness of substrate used in such binder equally.
U.S. Pat 5,203,764 people such as (, 1993) Libbey relate to and adopt the foam spacer that opens wide micropore, and this liner is made by the ade foam piece, and this foam piece is with the polyurethane prepolymer resin impregnated of the isocyanates Guan Nengtuan of band water cure, to bind up a wound.This liner also can be used as the orthopedic liner of apparatus and uses.
U.S. Pat 5,264,218 (Rogozinski, 1993) relate to a kind of dressings that is used for wound or skin ulcer, and this dressings comprises semi permeable, a transparent polyurethane and many concentric polyethylene rings or disk.
Yet, even do not have one piece of prior art patent to propose or narrate a kind of next to the shin and when binder wt is very little, yet keep the disposable binding agent binder product that connects for the strong viscosity of the adhesion strength of wearer's skin.
The present invention relates to a kind of height disposable adhesive bandage next to the shin.More particularly, it relate to a kind of height next to the shin, cover the disposable binding agent binder that the part of wound constitutes by a backing material next to the shin, layer of adhesive and one.
Backing material preferably is made of a foam or a fiber substrate, and this foam or fiber substrate and wearer's skin height is next to the shin.Can measure property next to the shin in various manners, particularly use stress/strain modulus method.The stress/strain modulus of product of the present invention should be lower, and promptly it should have the low strained stress of per unit.The stress/strain of product of the present invention relation should be when 20% strain when 0.5 pound/inch and 50% strain between 1.5 pounds/inch.
The binding agent composition that is used for product of the present invention is the biocompatible or contact adhesive that adapts of those skins through clinical proof and wearer preferably.For product of the present invention, can with than previous in order to keep being bonded at the amount of binding agent composition still less required on wearer's the skin.Further, can be with the littler binding agent of aggressivity.This is because product of the present invention is easy to crookedly and move with wearer's skin, and does not apply the power of this motion of resistance, and this motion is drawn back binder usually from skin.This just makes product of the present invention to wearer's skin irritation still less and prevented to cause the infringement of skin owing to removing binder valuably.
Absorption pad in the absorption pad of product of the present invention preferably can be absorbed into and be accommodated in by a wound release portion that is tending towards contacting wound itself and a wound effluent constitutes.
Fig. 1 is the bottom plan view according to the disposable binder of made of the present invention.
Fig. 2 is the bottom plan view according to the disposable binder of made of the present invention.
Fig. 3 is the bottom plan view according to the disposable binder of made of the present invention.
Fig. 4 is the figure of explanation from the resulting data of test of several binders of measurement maximum, force and strained functional relationship.
Fig. 5 is the figure of explanation from the resulting data of test of several binders of measurement recovery energy and strained functional relationship.
Fig. 6 is the figure of explanation from the resulting data of test of several binders of the disconnected intensity of measurement tension.
Fig. 7 is the figure of explanation from the resulting data of test of several binders of measurement maximum elongation.
Product of the present invention comprises three parts at least: the backing material of protecting the wound product cover part of binder of the present invention; contact with wound and for the wound effluent provides the wound covering part of this product that holds the place, and keep this product around wound binding agent composition in place.Can see some embodiment of binder of the present invention among Fig. 1,2 and 3.Among Fig. 1, binder 10 is disposable, removable, adherent binders of energy of one embodiment of the present of invention.Binder 10 is made of a backing material 20, an adhesive phase 30 and an absorption pad 40.Backing material 20 preferably is made of foam of polymers or the fibrous material of giving the suitable characteristic next to the shin of binder of the present invention.More preferably, backing material 20 is by polyvinyl chloride foam or thin film, polyethylene or the thin film of closed porosity, and perhaps polyurethane foam or thin film constitute.Non-woven fleece with individual features, for example, the meltblown non-woven fabric, contain the non-woven fleece of Kraton fiber as those, or spunbond nonwoven, all may be used to product of the present invention by the non-woven fleece that natural or synthetic cellulose fibres or the known fiber of other those of ordinary skills are made.The extension of backing material and restorability should be same or similar in all directions, so that provide suitable property next to the shin and intensity in all directions during wearing.
Backing material 20 preferably has 30 pounds/foot 3The plasticising of density and preferably about 20 mil thick polyvinyl chloride foam.The backing material of product of the present invention must have soft and elastic characteristic, so that produce the binder with characteristic of wanting required for the present invention.The density of polyvinyl chloride foam that is used for product of the present invention is preferably at about 25 pounds/foot 3With about 35 pounds/foot 3Between, and thickness is preferably between about 15 mils and about 25 mils.The backing material of this foamy thickness and prior art relatively for example compares with vinyl film, and a kind of cushion pad effect also is provided, and is subjected to external force to prevent wound.
Binding agent composition 30 is preferably any biocompatible contact adhesive.Its preferably a kind of water base or solvent based acrylates, the binding agent of rubber-based or binding agent or a kind of silicone adhesive agent of a kind of synthetic rubber base.More preferably, it is a kind of polyethylene ester group acryloid cement.The binding agent that is used for product of the present invention can have lower aggressivity, promptly compare with previous used binding agent, their adhesion values for steel can be lower, but that they will have when being used in combination with backing material of the present invention will be enough for adhering skin.For example, can be for the adhesion values of steel from about 4 ounces/inch to about 12 ounces/inch.The binding agent that is used for product of the present invention can also be those binding agents that are used for conventional bandages, but coating weight is lower, promptly from about 20g/m 2To about 40g/m 2, more preferably from about 25g/m 2To about 35g/m 2, most preferably be about 30g/m 2
Absorption pad 40 is a pad that comprises a wound release surface and the stratified of an absorber or become layer structure preferably.The wound release surface is designed to allow to be easy to remove and can not disturb the normal healing process or open wound once more from healing of wound, preferably makes this wound release surface with known polythene net fabric material of those of ordinary skills or suchlike thing.The absorber of absorption pad 40 is weaving or nonwoven batts of being made by some fibre, and these fibers are selected from following this natural or synthetic absorption of group and/or heat-sealable fibrous material, for example, and Cotton Gossypii, artificial silk polypropylene miser or suchlike thing.The absorber that absorbs liner 40 most preferably is to be made by the mixture of 90% polypropylene, 10% artificial silk, and this mixture can be used wound release surface thermally stratified layer.Absorber can be laminated on the wound release surface with radiation or ultrasonic energy, and perhaps they can be folded to together, so that the wound release surface is exposed to that side of binder contact wearer skin.Some other embodiment of Fig. 2 and 3 expressions disposable binder of the present invention show that they can make different shape and size, comprise but and are limited to those shape and size of being established in Fig. 2 and 3.
Product of the present invention preferably is enough on the comfortable skin that is fixed to the wearer and keeps removably connecting, and does not have the aggressivity binding agent to connect.Yet they should have enough elasticity also to return to approximate their original states with the shape that keeps them when removing from the stress that skin or body kinematics were applied.In the scope of the power that health and skin movements are produced, they need be easy to be consistent with health, and can withstand their suffered power when being used to joint, and they also should not move or itself apply undue pressure.
Recovery energy when required power (unit is a pound/inch) and this product one recover in the time of can being subjected to a given strain according to the binder that makes invention is measured substrate of the present invention and the needed performance of product.Connecing the tolerance that tensile strength when disconnected and elongation also are used for product of the present invention.Fig. 4 to 7 has illustrated with the test of being carried out according to following procedure and the data that obtain.
Power and strained functional relationship.
Can following ergometry and strained relation; Product of the present invention is placed under 70 ℃ of 4 hours and order conditions to temperature of 65% according to the TAPPI standard.Product is placed 2.5 " anchor clamps of the Instron testing machine of gauge length.Uphold this product in proper order to whole strained 20%, 50% and 100% with the speed of 5 inches of per minutes then.Each value measured uphold the required power of binder product and the width of sample is carried out regularization.Preferably, the strain for 20%, required power should be about 0.2 pound/inch to about 0.7 pound/inch, and for 50% strain, should be about 1.2 pounds/inch to about 1.8 pounds/inch.
Recover energy
Recover can, perhaps application of load and not the ratio of application of load energy be another key property of product of the present invention.This parameter has been measured the size of recovering energy when binder is loose by strain conditions.As measured to product of the present invention, the value of this parameter should be higher, so that guarantee binder permanent deformation not in use.Preferably, the strain to 20%, recovering can should be about 60% to about 70%, and for 50% strain, recovering should be about 40% to about 50%.Binder should keep bigger energy, so that acceptable strain in the use is provided.
The tension fracture strength
The tension fracture strength of product of the present invention is another useful tolerance of the property next to the shin requirement of product of the present invention.Can following measurement tension fracture strength: the load that increases continuously vertically is applied on the sample, and test being performed until fracture.By the value that observes fracture load on machine scale, scale or the recorder chart.Sample places the requirement of TAPPI, under 23 ℃, 50% relative humidity, 4 hours condition.Sample being remained between two anchor clamps of Instron testing machine and by the motion of evenly drawing anchor clamps makes sample produce strain.Initial gauge length is 2 ".To product with the time of breaking for 10 seconds speed stretching clamp with 20 inches of per minutes.If the time of breaking is less than 10 seconds, adjusting draw speed, to make the time of breaking be 10 seconds.The average pull-off force of product of the present invention should be between about 3.5 pounds and about 6 pounds of per inch.Preferably, it should be between about 4 pounds/inch and about 5 pounds/inch.
The maximum elongation amount
Therefore the maximum elongation amount is another variable of property next to the shin, and product of the present invention should be quite next to the shin, and can present the elongation of big percentage ratio and can not break.Can be with measuring maximum elongation as same device in the above-mentioned stretch breaking strength test.Yet, be the length of measuring the product when breaking, extended, rather than measure the required power of this product of breaking.Product of the present invention should have the maximum elongation at least about 150%, and preferably is at least about 200% of product original length.This has guaranteed can meet the profile of skin when product moves with displacement in dress.
Should make product of the present invention in such a way, so that during making, keep the property next to the shin and the intensity of backing material.Generally make disposable binder product with rolled material (rollstock).Preferably, assemble binder of the present invention like this, make other parts of backing material and final products keep apart, so that keep the performance of backing material.This can finish by it being rolled across on the cylinder (for example, vacuum drums), and this cylinder arrives absorption pad at backing material and quickens backing material before adhering to the backing material place.This make backing material present and the presenting of absorption pad between allow certain " becoming flexible " amount, kept the elastic property of backing material and can not uphold it.Like this, by make that backing material advances a little more hurry up than all the other element travel rates of product, backing material should be by loose before assembling.Although can coat or be applied with a doctor blade, preferably binding agent is applied on the backing material by transfer coated.Then, with binding agent the absorption pad that preferably forms a kind of lamination is adhered on the backing material.With co-applications of the present invention, common pendent U.S. Patent application (application number-, attorney docket J﹠amp; J1530) applying date is on April 8th, 1994, apply for simultaneously with this case) in the process of making product of the present invention has been described, quote this piece patent documentation herein as a reference.
Can use product of the present invention like this, disposable binder of the present invention is placed in wound or inflammation place, make it skin strong bonded with the wearer at the adhesive surface of backing material.If wound is open, absorption pad can absorb the wound effluent and prevent that it is further on fluent wearer's the skin and/or clothes.Further, can be before placing medicine on the skin and directly place on the liner.
Example 1
Make disposable binder according to method of the present invention.Backing material is the plastifying poly-ammonia vinyl foam of a kind of closed porosity, and this foam density is 30 pounds/foot 3, and thickness is 20 mils.Backing material with the acryloid cement coating is commercially available, about 30g/m 2The commercially available Avery EF3508 of Avery specialities band branch of Avery Dennison company that can Ohioan Painesville is coated on the foam.The absorption pad that the mixture of the polypropylene by 90%, 10% nylon constitutes is stacked on the side of a transparent polythene net fabric.The successive backing material that equals the whole length of required binder with a volume width prepares the bar shaped binder.Absorbent pad material has the width that equals required cushion region.Present backing material with vacuum drums, increase a little in the translational speed of vacuum drums place backing material.Then, in the vacuum drums downstream part speed of backing material that slows down, so that keep the elasticity of this material.Afterwards, absorbent pad material is added on the loose base material.The surface layer thin slice is placed on the exposed region of disposable binder, so that before placing on wearer's the skin, keep the binding agent of exposure.Be used in the drawing making surface layer thin slice that a side scribbles the bleaching of 13 pounds/polyethylene that makes and 40 pounds/order of AkrosilG9CO silicon steel release coat, although can make them with any releasable material that those of ordinary skills know.
Example 2
Test those disposable binders of being established in the example 1 as follows, whether can remain on wearer's the skin to determine them by method made of the present invention.Six disposable binders of the present invention are placed on the back surface of upper arm of first and second dactylus of finger of each hands and 24 human body experimental subjecies.Unrestricted to the normal activity of experimental subject and the custom of having a bath.Experimental subject was worn binder 24 hours.Checking experiment object when 24 hours finish, and determine that binder of the present invention keeps remaining untouched with a kind of acceptable manner and is bonded on one's body the experimental subject.
Example 3
The binder of being established in the example 1 according to method made of the present invention is subjected to maximum, force and strained function, load and energy and strained function, recovers the test that energy, tension fracture strength and percentage ratio extend.Also check other products.Product A and C are with the of the present invention product of plasticised polyvinyl chloride foam according to the method made of example 1.The density of the backing material of product A and B is 30 pounds/foot 3And thickness is 20 mils.The backing material of product B is 30 pounds/foot of density 3With the polyvinyl chloride foam of thickness 20 mils, but harder than foam used among product A and the C.Product D is the transparent strip binder of Bandaid board, is the Johnson﹠amp from the Skillman of New Jersey; Johnson consumer products company is commercially available, and this strip binder has the vinyl backing material.Product E is a Bandaid board flexible fibre binder, is the Johnson﹠amp from the Skillman of New Jersey; Johnson consumer products company has bought, and this flexible fibre binder contains the textile fabric backing material.Product F is a kind of movable strip soft foam binder, is commercially available from the 3M of Minnesotan Minneapolis, and this strip soft foam binder has the polyvinyl chloride foam substrate.
Test according to the method that the front is established.Established the result of maximum, force among Fig. 4 as the test of strained function.These tests show that product A and C have the relative value of the maximum, force of quite low every percent strain.This shows that it relatively is lower wanting crooked or being out of shape required maximum, force and other binder of binder.This point is for determining that it is important adopting binder of the present invention whether acceptable deformable degree is arranged.
Established the result that recovery can be tested among Fig. 5.This experimental measurement when one remove recover when making binder adhere to power on the given skin can size.The result of this test shows, particularly for still less strain, for product A and C, recovering can be higher; And also keep high recovery energy when relating to other underproof product or even for 100% strained situation.
By top step test tension fracture strength of establishing.Established the result of this test among Fig. 6.The tension fracture strength of product of the present invention is between about 3.5 pounds/inch and 5 pounds/inch.Like this, during the power of the backing material of these products in being subjected to manufacturing process,, just may rupture as it is not loose or supported during this process.This process allows to adopt the backing material with lower fracture strength.
Also tested the percentage ratio elongation of product A to F.Fig. 7 invading the exterior is understood the result.Product of the present invention has shown the elongation longer than any other products, for example, and 253% and 152%.Should be noted that except the situation for product E, adopt the draw speed of 20 inch per minute clocks to carry out elongation test, for the situation of product E, draw speed is 12 inch per minute clocks.The high percentage ratio elongation of product of the present invention has shown their shown height property next to the shin on performance.
By the explanation of the front of product of the present invention, other people can design alternative and equivalent structure, and this within the spirit and scope of the present invention.Like this, product of the present invention is not limited to those products in this special explanation.

Claims (1)

1. a disposable binding agent binder comprises a kind of backing material that can be next to the shin, and layer of adhesive and an absorption pad, described binding agent binder have yielding and return to the ability of its original form.
CNB951051245A 1994-04-08 1995-04-08 Conformable adhesive bandages Expired - Fee Related CN1191799C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US225171 1988-07-28
US22517194A 1994-04-08 1994-04-08
US225,171 1994-04-08

Publications (2)

Publication Number Publication Date
CN1116516A true CN1116516A (en) 1996-02-14
CN1191799C CN1191799C (en) 2005-03-09

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Application Number Title Priority Date Filing Date
CNB951051245A Expired - Fee Related CN1191799C (en) 1994-04-08 1995-04-08 Conformable adhesive bandages

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JP (1) JPH0838543A (en)
CN (1) CN1191799C (en)
BR (1) BR9501513A (en)
CA (1) CA2146615C (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103607983A (en) * 2011-04-15 2014-02-26 于尔戈实验室 Hydrocellular absorbent dressing, and use thereof for treatment of chronic and acute wounds
CN104244879A (en) * 2012-04-20 2014-12-24 科洛普拉斯特公司 An adhesive wafer
CN104363873A (en) * 2012-04-02 2015-02-18 旋转护理公司 Patient-orienting alternating pressure decubitus prevention support apparatus
CN107405012A (en) * 2014-12-22 2017-11-28 甘特创意有限公司 Protective articles
CN108430408A (en) * 2015-12-23 2018-08-21 卡尔·奥托·布劳恩两合公司 Bandage
CN109731122A (en) * 2019-03-20 2019-05-10 安徽省康富医疗用品有限公司 A kind of non-latex self-adhesive elastic bandage of hemostasis type and preparation method thereof

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Publication number Priority date Publication date Assignee Title
US3665918A (en) * 1970-01-12 1972-05-30 Johnson & Johnson Conformable adhesive sheet
US4341209A (en) * 1981-01-12 1982-07-27 The Kendall Company Adhesive bandage with foam backing
EP0099748B1 (en) * 1982-07-21 1987-05-27 Smith and Nephew Associated Companies p.l.c. Adhesive wound dressing
GB2228682B (en) * 1989-02-23 1992-08-12 Ultra Lab Ltd Wound dressing
JPH077940Y2 (en) * 1989-12-07 1995-03-01 ニチバン株式会社 Medical patch
JPH03195554A (en) * 1989-12-26 1991-08-27 Dia Seiyaku Kk Emergency adhesive tape
KR960000740B1 (en) * 1990-03-30 1996-01-13 미네소타 마이닝 앤드 매뉴팩츄어링 컴패니 Elastomeric tapes with microtextured skin layers
AU2625192A (en) * 1991-11-01 1993-05-06 Ferris Mfg. Corp. Window dressing

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103607983A (en) * 2011-04-15 2014-02-26 于尔戈实验室 Hydrocellular absorbent dressing, and use thereof for treatment of chronic and acute wounds
CN103607983B (en) * 2011-04-15 2016-08-17 于尔戈实验室 Hydrocellular absorbent dressing and the purposes in processing chronic wounds and acute wounds thereof
CN104363873A (en) * 2012-04-02 2015-02-18 旋转护理公司 Patient-orienting alternating pressure decubitus prevention support apparatus
CN104244879A (en) * 2012-04-20 2014-12-24 科洛普拉斯特公司 An adhesive wafer
CN104244879B (en) * 2012-04-20 2017-09-26 科洛普拉斯特公司 Adhesive sheet
CN107405012A (en) * 2014-12-22 2017-11-28 甘特创意有限公司 Protective articles
CN108430408A (en) * 2015-12-23 2018-08-21 卡尔·奥托·布劳恩两合公司 Bandage
CN109731122A (en) * 2019-03-20 2019-05-10 安徽省康富医疗用品有限公司 A kind of non-latex self-adhesive elastic bandage of hemostasis type and preparation method thereof

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Publication number Publication date
CA2146615C (en) 2007-06-05
BR9501513A (en) 1995-11-07
CA2146615A1 (en) 1995-10-09
CN1191799C (en) 2005-03-09
JPH0838543A (en) 1996-02-13

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