CN111643124A - Sweat sample collecting and storing device - Google Patents

Sweat sample collecting and storing device Download PDF

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Publication number
CN111643124A
CN111643124A CN202010541362.7A CN202010541362A CN111643124A CN 111643124 A CN111643124 A CN 111643124A CN 202010541362 A CN202010541362 A CN 202010541362A CN 111643124 A CN111643124 A CN 111643124A
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CN
China
Prior art keywords
sweat
hydrophilic substance
plug
layer
sample collection
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Pending
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CN202010541362.7A
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Chinese (zh)
Inventor
江婧婧
赵秀梅
郝建秀
尹鹏滨
张蔓丽
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Chinese PLA General Hospital
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Chinese PLA General Hospital
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Publication date
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Priority to CN202010541362.7A priority Critical patent/CN111643124A/en
Publication of CN111643124A publication Critical patent/CN111643124A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/0064Devices for taking samples of body liquids for taking sweat or sebum samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0096Casings for storing test samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00Devices for applying media, e.g. remedies, on the human body

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention belongs to the field of detection devices, and particularly discloses a sweat specimen collecting and storing device which comprises a collecting unit and a separating unit, wherein the collecting unit comprises a waterproof layer, a hydrophilic substance coating layer arranged on the waterproof layer, a skin-friendly layer arranged on the hydrophilic substance coating layer and protective layers which are stuck to two ends of the inner surface of the waterproof layer and are detachably arranged on the waterproof layer, a plurality of air holes are formed in the skin-friendly layer, and sweat irritants are adsorbed on the hydrophilic substance coating layer; the separation element include the outer tube, arrange the inside inner tube of outer tube in and arrange the stopcock of inner tube upper end in, the upper portion of outer tube can block the pipe shaft of inner tube and prevent the inner tube landing, the lower part of inner tube sets up a plurality of meshes that are used for filtering out the sweat, the device can carry out long-time sweat collection to arbitrary position, and the collection volume is big, the sweat sample collection that can be more accurate feeds back human index situation through the analysis of sweat comes.

Description

Sweat sample collecting and storing device
Technical Field
The invention belongs to the field of detection devices, and particularly relates to a sweat sample collecting and storing device.
Background
With the rising of the attention to health, the demand of people on monitoring various indexes of a body is leapfrog, the health condition of the body can be tracked and mastered through the detection of blood, interstitial fluid or sweat, the detection of the blood and the interstitial fluid can cause certain damage to the body, and therefore the non-invasive detection by utilizing the sweat is a trend. Human sweat contains sodium, chloride, lactic acid, urea and small amounts of proteins, polypeptides and metal ions. The components of sweat may reflect the health of the human body. Such as: dehydration, cystic fibrosis, childhood pancreatic disease, and the like. Meanwhile, human sweat collection is also applied to athletes or troops in high-temperature training, and a large amount of water and inorganic salt are lost particularly in the operation of wearing protective equipment, so that the harm is brought to systems of cardiovascular and the like of operating personnel, and the movement capacity of the body is reduced. Collecting sweat, measuring sweat amount, analyzing the influence of sweat on metabolism of water, electrolyte, protein and other matters of the body, and providing scientific basis for water and salt replenishment of high temperature worker. The sweating rate is one of the indexes of human body thermal stress, which is obviously related to the environmental heat intensity, and the biological indexes of different working time are closely related to the environmental heat intensity index, and the working tolerance time limit under the thermal environment can be measured and calculated through the relations. People often use the nude weight difference method, dressing weight difference method and gauze weight increase method before and after exercise to express the sweat amount to reflect the weight bearing limit of the human body, which can not accurately reflect the physical condition of athletes or soldiers.
Chinese patent CN2910156Y discloses a sweat collection bag, which solves the problem that sweat on the forehead of a doctor is easy to drop into an operation area to cause pollution in the surgical operation process. The sweat collection bag comprises a sweat absorption layer and a fastening body, wherein waterproof layers are arranged on the outer side and the bottom side of the sweat absorption layer, a liquid collection cavity is arranged at the end part of the sweat absorption layer, and the collection bag cannot conveniently collect sweat and store and analyze other parts of a body.
Traditional sweat collector scrapes the collection through the material that adsorbs the sweat to skin, at first can't accurately know when the person of being gathered perspires, and what position perspires can't effectively carry out long-time sweat collection to skin, and the volume of gathering is very little, therefore the result that detects is also inaccurate.
Disclosure of Invention
In order to solve the problems, the invention provides a sweat sample collecting and storing device which can collect sweat at any part for a long time, has large collection amount and can feed back index conditions of a human body more accurately through sweat analysis, and the sweat sample collecting and storing device comprises the following specific contents:
the invention provides a sweat specimen collecting and storing device, which comprises a collecting unit and a separating unit, wherein the collecting unit is not connected with the separating unit, the collecting unit comprises a waterproof layer and a hydrophilic substance coating layer arranged on the waterproof layer, the skin-friendly layer and the waterproof layer form a containing cavity capable of containing the hydrophilic substance coating layer, the skin-friendly layer arranged on the hydrophilic substance coating layer and protective layers which are stuck to two ends of the inner surface of the waterproof layer and are detachably arranged on the waterproof layer are provided with a plurality of air holes, and sweat irritants are adsorbed on the hydrophilic substance coating layer;
the separation unit comprises an outer tube, an inner tube arranged in the outer tube and a tube plug used for sealing the upper ends of the outer tube and the inner tube, wherein the lower part of the inner tube is provided with a plurality of meshes used for filtering sweat.
Further, the sweat stimulant is one of acetylcholine or pilocarpine.
Further, the sweat stimulant is added in an amount of 0.2-0.6 μ g/cm2
Furthermore, the protective layer and the waterproof layer are both prepared from water-proof hydrophobic substances.
Further, the water-blocking hydrophobic substance is at least one of PU soft polyurethane, silane polymer or fluorine-containing acrylate polymer.
Further, the hydrophilic substance coating layer contains a hydrophilic substance.
Further, the hydrophilic material is at least one of rayon and a polyester film.
Further, the hydrophilic substance is at least one of kapok fiber, sodium acrylate and polyesteramide fiber.
Further, the pipe plug comprises an inner plug for sealing the inner pipe and an outer plug for sealing the outer pipe, wherein the inner plug is arranged in the middle of the outer plug, and the inner plug and the outer plug are integrally formed.
Furthermore, the inner plug is connected with the inner pipe through threads or is embedded into the inner pipe, and the outer plug is connected with the outer pipe through threads.
Compared with the prior art, the invention has the beneficial effects that:
1. the sweat sample collecting unit can be adhered to any part of a human body, can collect sweat at any part for a long time, has large collecting amount, and can feed back index conditions of the human body more accurately through sweat analysis.
2. The protective layer and the waterproof layer of the sweat specimen collecting unit can protect the hydrophilic substance bag when not in use, are convenient to store, and can be torn off and adhered to a human body when in use, so that the sweat specimen collecting unit is convenient to operate at any time.
3. The skin-friendly layer in the sweat specimen collecting unit is coated with at least one of acetylcholine or pilocarpine, so that sweat gland can be stimulated to secrete sweat, and sweat can be collected conveniently for some collected persons who are not easy to sweat.
4. The hydrophilic substance coating of the sweat sample collection unit absorbs sweat and then is conveniently taken out to be separated and collected by the separation unit.
Drawings
FIG. 1 is a cross-sectional view of an acquisition unit of the present invention;
FIG. 2 is a top view of an acquisition unit of the present invention;
fig. 3 is an exploded assembly view of the separation unit of the present invention.
FIG. 4 is a cross-sectional view of a separation unit of the present invention;
fig. 5 is a state diagram of the acquisition unit of the present invention in use.
1-a protective layer; 2-a skin-friendly layer; 3-a hydrophilic substance coating; 4-waterproof layer; 5-inner tube; 6-outer tube; 7-pipe plug; 8-inner plug, 9-mesh; 10-a containment chamber; 11-outer plug.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below so that those skilled in the art can better understand the advantages and features of the present invention, and thus the scope of the present invention will be more clearly defined. The embodiments described herein are only a few embodiments of the present invention, rather than all embodiments, and all other embodiments that can be derived by one of ordinary skill in the art without inventive faculty based on the embodiments described herein are intended to fall within the scope of the present invention.
The sweat sample collection and preservation device comprises a collection unit (shown in figures 1 and 2) for sweat collection and a separation unit (shown in figures 3 and 4) for sweat separation, wherein the collection unit (shown in figures 1 and 2) and the separation unit (shown in figures 3 and 4) are not connected with each other, and the collected sweat is separated, preserved and detected by the separation unit after the collection unit collects the sweat.
The collecting unit of the invention comprises a waterproof layer 4, a hydrophilic substance coating layer 3 arranged on the waterproof layer 4, a skin-friendly layer 2 arranged on the hydrophilic substance coating layer 3 and protective layers 1 which are adhered to two ends of the inner surface of the waterproof layer 4 and are detachably arranged on the waterproof layer 4. When the sweat collecting device is used, the protective layer 1 is torn off, the adhesive on the waterproof layer 4 is exposed, and the sweat collecting device is convenient to adhere to skin and collect sweat. The skin-friendly layer 2 is provided with a plurality of air holes, and the skin-friendly layer 2 is provided with an opening capable of being adhered and used for placing the hydrophilic substance coating 3 into the accommodating cavity 10 between the skin-friendly layer 2 and the waterproof layer 4. The hydrophilic substance coating 3 of the invention adsorbs sweat stimulant which stimulates sweat gland to secrete sweat, wherein the addition amount of the sweat stimulant is 0.2-0.6 mu g/cm2One of acetylcholine or pilocarpine. The protective layer 1 and the waterproof layer 4 are both prepared from waterproof and hydrophobic substances, and the waterproof and hydrophobic substances are at least one of PU soft polyurethane, silane polymer or fluorine-containing acrylate polymer. Wherein the hydrophilic substance coating 3 contains hydrophilic substance which is at least one of artificial fiber or polyester film, and is hydrophilicThe material is at least one of kapok fiber, sodium acrylate and polyesteramide fiber.
The separation unit of the present invention comprises an outer tube 6, an inner tube 5 disposed inside the outer tube 6, and a plug 7 for sealing the upper ends of the outer tube 6 and the inner tube 5, and a plurality of meshes 9 for filtering out sweat are provided at the lower portion of the inner tube 5. The pipe plug 7 comprises an inner plug 8 for sealing the inner pipe 5 and an outer plug 11 for sealing the outer pipe 6, the inner plug 8 is arranged in the middle of the outer plug 11, the inner plug 8 and the outer plug 11 are integrally formed, and by means of the design, the separation unit is good in sealing performance, and sweat obtained by separation cannot be polluted. The inner plug 8 is connected with the inner pipe 5 through screw threads or embedded connection, and the outer plug 11 is connected with the outer pipe 6 through screw threads.
The use method of the sweat sample collecting and storing device provided by the invention comprises the following steps: when the device is used as shown in fig. 5, the hydrophilic substance coating 3 is placed into the accommodating cavity (10) formed by the skin-friendly layer 2 and the waterproof layer 4 on the collecting unit through the adhesive opening on the skin-friendly layer 2, the adhesive opening on the skin-friendly layer 2 is pinched, the protective layers 1 on two sides are respectively torn down towards two sides, the adhesive on the waterproof layer 4 is exposed and attached to the skin of a human body, the waterproof layer 4 and the skin-friendly layer 2 are integrally attached to the skin of the human body to be collected, and sweat irritants on the hydrophilic substance coating 3 stimulate the skin of the human body to sweat, so that the sweat is absorbed and collected.
Treat that hydrophilic substance covering 3 gathers and accomplish sweat, take out it from the opening that can bond on close skin layer 2 and put into the inner tube 5 of separation element, this inner tube 5 lower part sets up mesh 9, put into centrifuge with the separation element after, the sweat that hydrophilic substance covering 3 adsorbs is thrown away by centrifugal force, the sweat leaks to outer tube 6 through mesh 9 of inner tube 5 lower part and stores, take out inner tube 5 after, can directly move to the cryopreserving pipe with the sweat in the outer tube 6, reach the effect that the sweat sample was preserved.
The present invention provides only one sweat sample collection and preservation device, and the method and the way for implementing the technical solution are many, and the above description is only the preferred embodiment of the present invention, it should be noted that, for those skilled in the art, without departing from the principle of the present invention, several improvements and modifications can be made, and these improvements and modifications should be regarded as the protection scope of the present invention, and all the components not specified in the present embodiment can be implemented by the prior art.

Claims (10)

1. The utility model provides a sweat sample collection save set which characterized in that: the sweat specimen collecting and storing device comprises a collecting unit and a separating unit, wherein the collecting unit is not connected with the separating unit, the collecting unit comprises a waterproof layer (4), a hydrophilic substance coating (3) arranged on the waterproof layer (4), a skin-friendly layer (2) arranged on the hydrophilic substance coating (3) and protective layers (1) which are stuck to two ends of the inner surface of the waterproof layer (4) and are detachably arranged on the waterproof layer (4), the skin-friendly layer (2) and the waterproof layer (4) form a containing cavity (10) capable of containing the hydrophilic substance coating (3), a plurality of air holes are formed in the skin-friendly layer (2), and sweat irritants are adsorbed on the hydrophilic substance coating (3);
the separation unit comprises an outer tube (6), an inner tube (5) arranged inside the outer tube (6) and a tube plug (7) used for sealing the upper ends of the outer tube (6) and the inner tube (5), wherein the lower part of the inner tube (5) is provided with a plurality of meshes (9) used for filtering sweat.
2. The sweat sample collection and preservation device of claim 1, wherein: the sweat stimulant is one of acetylcholine or pilocarpine.
3. A sweat sample collection and preservation device according to either one of claims 1 or 2, wherein: the addition amount of the sweat stimulant is 0.2-0.6 mu g/cm 2.
4. The sweat sample collection and preservation device of claim 1, wherein: the protective layer (1) and the waterproof layer (4) are both prepared from waterproof hydrophobic substances.
5. The sweat sample collection and preservation device of claim 4, wherein: the waterproof hydrophobic substance is at least one of PU soft polyurethane, silane polymer or fluorine-containing acrylate polymer.
6. The sweat sample collection and preservation device of claim 1, wherein: the hydrophilic substance coating (3) contains a hydrophilic substance.
7. The sweat sample collection and preservation device of claim 6, wherein: the hydrophilic substance is at least one of artificial fiber or polyester film.
8. The sweat sample collection and preservation device of claim 6, wherein: the hydrophilic substance is at least one of kapok fiber, sodium acrylate and polyesteramide fiber.
9. A sweat sample collection and preservation device according to claim 1, wherein: the pipe plug (7) comprises an inner plug (8) for sealing the inner pipe (5) and an outer plug (11) for sealing the outer pipe (6), the inner plug (8) is arranged in the middle of the outer plug (11), and the inner plug (8) and the outer plug (11) are integrally formed.
10. A sweat sample collection and preservation device according to claim 9, wherein: the inner plug (8) is connected with the inner pipe (5) in a threaded or embedded mode, and the outer plug (11) is connected with the outer pipe (6) in a threaded mode.
CN202010541362.7A 2020-06-15 2020-06-15 Sweat sample collecting and storing device Pending CN111643124A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010541362.7A CN111643124A (en) 2020-06-15 2020-06-15 Sweat sample collecting and storing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010541362.7A CN111643124A (en) 2020-06-15 2020-06-15 Sweat sample collecting and storing device

Publications (1)

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CN111643124A true CN111643124A (en) 2020-09-11

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113558615A (en) * 2021-06-22 2021-10-29 深圳大学 Sweat sensor, preparation method thereof and sweat detection method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113558615A (en) * 2021-06-22 2021-10-29 深圳大学 Sweat sensor, preparation method thereof and sweat detection method

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