CN111607502A

CN111607502A - Varicella virus stock solution preparing device

Info

Publication number: CN111607502A
Application number: CN202010490973.3A
Authority: CN
Inventors: 杨峰; 李晓帆; 王文成; 王洋
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-06-02
Filing date: 2020-06-02
Publication date: 2020-09-01

Abstract

The invention relates to the technical field of virus preparation, and discloses a varicella virus stock solution preparation device which comprises a bottom plate, wherein side plates are arranged on the left side and the right side of the upper surface of the bottom plate, fixing plates are arranged in the middle of the side plates, grinding grooves are formed in the middle of the two fixing plates, water permeable holes are formed in the bottoms of the grinding grooves, a top plate is arranged at the top of the side plates, guide rods are slidably connected to the front side and the rear side of the top plate, limiting blocks are arranged at the upper ends of the guide rods, springs are arranged between the limiting blocks and the top plate, the lower ends of the guide rods are fixedly connected with the upper surface of a lifting plate, a driving motor is arranged on the right side of the upper surface of the lifting plate, an output shaft of the driving motor is fixedly connected with a first rotating shaft, a first belt wheel is arranged in. The invention is suitable for a varicella virus stock solution preparing device, and the raw materials are ground and processed by arranging a grinding head and a grinding groove in the device.

Description

Varicella virus stock solution preparing device

Technical Field

The invention relates to the technical field of virus preparation, in particular to a varicella virus stock solution preparation device.

Background

Varicella-zoster virus is called varicella-zoster virus, because it causes varicella in children after primary infection, and the virus remains in the body after recovery, and the virus recurs to cause herpes zoster in a small number of patients after adults. Varicella is a common disease with high infectivity for children, which is better at 2-6 years old, the infection source is mainly patients, and the varicella content and respiratory tract secretion in the acute stage of the patients contain viruses. In order to better treat the varicella, in the research process, a varicella virus stock solution is usually prepared, and then various detections and researches are carried out on the stock solution, wherein relevant preparation equipment is needed.

Chinese patent (publication No. CN207169095U) discloses a plant leaf cell sap extraction device, which comprises a shell, wherein a first groove body and a second groove body are arranged on the shell, a heater is fixedly arranged at the bottom of the first groove body, a fixing net is fixedly arranged on the inner wall of the first groove body and is positioned right above the heater, an inner rod is arranged in the first groove body, a support plate is fixedly arranged at the bottom end of the inner rod, the device is provided with the first groove body and the second groove body on the shell, a blade capable of cutting off plant leaves is arranged in the first groove body, the blade is connected to an outer rod and can be placed in the first groove body, thus the heating time can be shortened, the leaf cell sap is evaporated quickly, the heater is started to heat the leaves in the first groove body, gas after the cell sap is evaporated enters a condenser through a connecting pipe to be condensed into liquid, then enters a storage tank from the liquid outlet pipe for storage, however, the device is applied to the extraction of plant cell sap, and the cell is needed to be ground when the animal cell sap is extracted, so that the cell wall is damaged, and therefore, the device needs to be improved.

Disclosure of Invention

The invention provides a varicella virus stock solution preparing device, which solves the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

a varicella virus stock solution preparing device comprises a bottom plate, side plates are arranged on the left side and the right side of the upper surface of the bottom plate, fixed plates are arranged in the middle of the side plates, grinding grooves are formed in the middle of the two fixed plates, water permeable holes are formed in the bottoms of the grinding grooves, a top plate is arranged at the top of each side plate, guide rods are slidably connected with the front side and the rear side of each top plate, a limiting block is arranged at the upper end of each guide rod, a spring is arranged between each limiting block and the corresponding top plate, the lower end of each guide rod is fixedly connected with the upper surface of a lifting plate, a driving motor is arranged on the right side of the upper surface of the lifting plate, an output shaft of the driving motor is fixedly connected with a first rotating shaft, a first belt wheel is arranged in the middle of the first rotating shaft, the first belt wheel is connected with a second belt wheel through a first belt, the second belt wheel is, the rear end of the first rotating shaft is provided with a third belt wheel, the third belt wheel is connected with a fourth belt wheel through a second belt, the fourth belt wheel is fixedly connected with the rear end of a screw rod, and the middle part of the screw rod is in threaded connection with the left end and the right end of the grinding head.

As a preferable technical scheme of the invention, the middle part of the lifting plate is provided with a yielding port which penetrates through the lower part of the connecting rack.

As a preferable technical scheme of the invention, the middle part of the upper surface of the lifting plate is provided with a second fixed seat, and the upper part of the second fixed seat is rotatably connected with the front side and the rear side of the second rotating shaft.

As a preferable technical solution of the present invention, a first fixing seat is disposed on the right side of the upper surface of the lifting plate, and an upper portion of the first fixing seat is rotatably connected to the rear side of the first rotating shaft.

As a preferable technical scheme of the invention, the left side and the right side of the lower surface of the lifting plate are provided with third fixed seats, and the lower parts of the third fixed seats are rotatably connected with the front side and the rear side of the screw rod.

As a preferable technical scheme of the invention, the middle part of the screw rod is provided with a double-spiral chute.

As a preferred technical scheme of the invention, the lower part of the side plate is provided with the drainage plate, and the front side and the rear side of the upper surface of the drainage plate are provided with the guide plates.

As a preferable technical scheme of the invention, a supporting plate is arranged between the lower surface of the drainage plate and the left side plate.

As a preferred technical scheme of the invention, the right side of the upper surface of the bottom plate is provided with a storage barrel which is positioned right below the right end of the drainage plate.

As a preferable technical scheme of the invention, the upper surface of the fixing plate is provided with a bracket, and the upper part of the bracket is provided with a nozzle.

The invention has the following advantages:

the invention is suitable for a varicella virus stock solution preparing device, the raw materials are ground and processed by arranging the grinding head and the grinding groove in the device, and the lifting plate which can move up and down is arranged, so that the grinding head is separated from the grinding groove after working for a period of time, the raw materials in the grinding groove can automatically expand and then are continuously ground, the repeated grinding can improve the grinding effect, and the extraction liquid can be added into the grinding gap, thereby improving the use convenience of the device.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic view showing a varicella virus stock solution preparing apparatus.

FIG. 2 is a front view of a varicella virus original liquid preparing apparatus.

FIG. 3 is a schematic view showing the structure of a varicella virus stock solution preparing apparatus in which a gear with teeth is engaged with a rack.

In the figure: 1. a base plate; 2. a side plate; 3. a support plate; 4. a drainage plate; 5. a guide plate; 6. a fixing plate; 7. a support; 8. a nozzle; 9. a grinding groove; 10. water permeable holes; 11. a top plate; 12. a guide bar; 13. a spring; 14. a limiting block; 15. a storage bucket; 16. a lifting plate; 17. a second fixed seat; 18. a second rotating shaft; 19. a gear with missing teeth; 20. a rack; 21. a let position port; 22. a second pulley; 23. a drive motor; 24. a first rotating shaft; 25. a first pulley; 26. a first belt; 27. a first fixed seat; 28. a third belt pulley; 29. a fourth pulley; 30. a second belt; 31. a third fixed seat; 32. a grinding head; 33. and a screw rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example one

Referring to fig. 1-3, a varicella virus stock solution preparing device comprises a bottom plate 1, side plates 2 are arranged on the left side and the right side of the upper surface of the bottom plate 1, fixing plates 6 are arranged in the middle of the side plates 2, grinding grooves 9 are arranged in the middle of the two fixing plates 6, water permeable holes 10 are arranged at the bottoms of the grinding grooves 9, a top plate 11 is arranged at the top of each side plate 2, a drainage plate 4 is arranged on the lower portion of each side plate 2, guide plates 5 are arranged on the front side and the rear side of the upper surface of each drainage plate 4, a supporting plate 3 is arranged between the lower surface of each drainage plate 4 and the side plate 2 on the left side, a storage barrel 15 is arranged on the right side of the upper surface of the.

The front side and the rear side of the top plate 11 are slidably connected with guide rods 12, the upper end of each guide rod 12 is provided with a limit block 14, a spring 13 is arranged between each limit block 14 and the top plate 11, the lower end of each guide rod 12 is fixedly connected with the upper surface of a lifting plate 16, the right side of the upper surface of each lifting plate 16 is provided with a driving motor 23, the output shaft of each driving motor 23 is fixedly connected with a first rotating shaft 24, the right side of the upper surface of each lifting plate 16 is provided with a first fixed seat 27, the upper part of each first fixed seat 27 is rotatably connected with the rear side of the corresponding first rotating shaft 24, the middle part of each first rotating shaft 24 is provided with a first belt wheel 25, each first belt wheel 25 is connected with a second belt wheel 22 through a first belt 26, each second belt wheel 22 is fixedly connected with the rear end of a second rotating shaft 18, the middle part of the upper surface of each lifting plate 16 is provided with a second fixed seat, the left side of the gear lacking gear 19 is meshed with the middle of the rack 20, the middle of the lifting plate 16 is provided with a position yielding port 21, the position yielding port 21 is connected with the lower portion of the rack 20 in a penetrating mode, the upper end of the rack 20 is fixedly connected with the top plate 11, the rear end of the first rotating shaft 24 is provided with a third belt wheel 28, the third belt wheel 28 is connected with a fourth belt wheel 29 through a second belt 30, the fourth belt wheel 29 is fixedly connected with the rear end of a screw rod 33, the left side and the right side of the lower surface of the lifting plate 16 are provided with third fixing seats 31, the lower portion of the third fixing seats 31 is rotatably connected with the front side and the rear side of the screw rod 33, the middle of the screw rod 33.

Example two

Referring to fig. 1, the other contents of the present embodiment are the same as those of the first embodiment, except that: the upper surface of the fixed plate 6 is provided with a bracket 7, and the upper part of the bracket 7 is provided with a nozzle 8. In order to make the cell fluid inside the cell can be better separated after the cell is broken, an extractant can be added after the cell is ground, so that the nozzle 8 is arranged at the upper part of the fixing plate 6, the nozzle 8 is connected with a storage device of the extractant, and the extractant can be sprayed into the grinding groove 9 through the nozzle 8 after the grinding head 32 is separated from the grinding groove 9 every time, so that the extraction effect of the cell fluid is improved through the extractant.

In the implementation process of the invention, firstly, cell raw materials to be ground are added into a grinding groove 9, at this time, a driving motor 23 is started, an output shaft of the driving motor 23 drives a first rotating shaft 24 to rotate, the rear end of the first rotating shaft 24 drives a screw 33 to rotate through a third belt wheel 28, a second belt 30 and a fourth belt wheel 29, because a double-spiral chute is arranged in the middle of the screw 33, when the screw 33 rotates, a grinding head 32 moves back and forth along the direction of the screw 33, meanwhile, the first rotating shaft 24 also drives a gear lacking gear 19 to rotate through a first belt wheel 25, a first belt 26 and a second belt wheel 22, the gear lacking gear 19 rotates anticlockwise, when a tooth part of the gear lacking gear 19 is meshed with a rack 20, the gear lacking gear 19 moves upwards along the rack 20, so that a lifting plate 16 moves upwards, the grinding head 32 moves upwards and is separated from the grinding groove 9, when the gear lacking gear 19 is separated from the rack 20, under the action of gravity and the spring 13 of the spring 13, the lifting plate 16 moves downwards, so that the grinding head 32 is pressed against the bottom of the grinding groove 9, and at the moment, the grinding head 32 moves back and forth along with the screw 33, so that the cell raw material in the grinding groove 9 is ground, the cell wall is broken after the cell is ground, the virus stock solution and the cell solution in the cell flow out and drop onto the drainage plate 4 through the water permeable hole 10, because the right end of the drainage plate 4 inclines downwards, and the guide plate 5 is further arranged on the upper surface of the drainage plate 4, the cell solution flows to the right side along with the drainage plate 4 and finally flows into the storage barrel 15 arranged above the bottom plate 1, sometimes, in order to save steps, the storage barrel 15 is replaced by the inlet of a centrifuge, so that the prepared cell solution directly flows into the centrifuge, and the centrifuge processes the stock solution centrifugally, so as to obtain virus stock solution with higher purity; the invention is suitable for a varicella virus stock solution preparing device, the raw materials are ground by arranging a grinding head 32 and a grinding groove 9 in the device, and the lifting plate 16 which can move up and down is arranged, so that the grinding head 32 is separated from the grinding groove 9 after working for a period of time, the raw materials in the grinding groove 9 can automatically expand and then are continuously ground, the repeated grinding can improve the grinding effect, and extract liquor can be added into the grinding gap, thereby improving the use convenience of the device.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. A varicella virus stock solution preparing device comprises a bottom plate (1), side plates (2) are arranged on the left side and the right side of the upper surface of the bottom plate (1), fixing plates (6) are arranged in the middle of the side plates (2), grinding grooves (9) are arranged in the middle of the two fixing plates (6), water permeable holes (10) are formed in the bottoms of the grinding grooves (9), a top plate (11) is arranged at the top of the side plates (2), the varicella virus stock solution preparing device is characterized in that guide rods (12) are slidably connected to the front side and the rear side of the top plate (11), limiting blocks (14) are arranged at the upper ends of the guide rods (12), springs (13) are arranged between the limiting blocks (14) and the top plate (11), the lower ends of the guide rods (12) are fixedly connected with the upper surface of a lifting plate (16), a driving motor (23) is arranged on the right side of the upper, the middle part of first pivot (24) is equipped with first band pulley (25), and second band pulley (22) is connected through first belt (26) in first band pulley (25), the rear end of second band pulley (22) fixed connection second pivot (18), and the middle part of second pivot (18) is equipped with out tooth gear (19), and the middle part of rack (20) is connected in the meshing of missing tooth gear (19) left side, the upper end fixed connection roof (11) of rack (20), the rear end of first pivot (24) is equipped with third band pulley (28), and fourth band pulley (29) is connected through second belt (30) in third band pulley (28), the rear end of fourth band pulley (29) fixed connection lead screw (33), the left and right sides both ends of the middle part threaded connection grinding head (32) of lead screw (33).

2. The varicella virus original solution preparing apparatus according to claim 1, wherein the elevating plate (16) is provided with a relief opening (21) at a middle portion thereof, and the relief opening (21) is connected to a lower portion of the rack (20) in a penetrating manner.

3. The varicella virus original solution preparing device according to claim 1, wherein a second fixed seat (17) is provided in the middle of the upper surface of the lifting plate (16), and the upper part of the second fixed seat (17) is rotatably connected to the front and rear sides of the second rotary shaft (18).

4. The varicella virus original solution preparing device according to claim 1, wherein a first fixing seat (27) is provided on the right side of the upper surface of the lifting plate (16), and the upper portion of the first fixing seat (27) is rotatably connected to the rear side of the first rotary shaft (24).

5. The varicella virus original solution preparing device according to claim 1, wherein third fixing seats (31) are provided on the left and right sides of the lower surface of the lifting plate (16), and the lower portions of the third fixing seats (31) are rotatably connected to the front and rear sides of the screw rod (33).

6. The varicella virus original solution producing device according to claim 1 or 5, wherein a double spiral chute is provided in the middle of the screw rod (33).

7. The varicella virus original solution preparing device according to claim 1, wherein the lower part of the side plate (2) is provided with a flow guide plate (4), and the front and rear sides of the upper surface of the flow guide plate (4) are provided with guide plates (5).

8. The varicella virus original solution preparing apparatus according to claim 7, wherein a support plate (3) is provided between the lower surface of the drainage plate (4) and the left side plate (2).

9. The varicella virus original solution preparing apparatus according to claim 7 or 8, wherein a storage tub (15) is provided on the right side of the upper surface of the bottom plate (1), and the storage tub (15) is located right below the right end of the flow guide plate (4).

10. The varicella virus original solution preparing apparatus according to claim 1, wherein a support (7) is provided on the upper surface of said fixing plate (6), and a nozzle (8) is provided on the upper portion of said support (7).