CN111603516A - Decoction for preventing and treating pneumonia and preparation method - Google Patents

Decoction for preventing and treating pneumonia and preparation method Download PDF

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Publication number
CN111603516A
CN111603516A CN202010400339.6A CN202010400339A CN111603516A CN 111603516 A CN111603516 A CN 111603516A CN 202010400339 A CN202010400339 A CN 202010400339A CN 111603516 A CN111603516 A CN 111603516A
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Prior art keywords
parts
decoction
pneumonia
preparation
drying
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CN202010400339.6A
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Inventor
沈献礼
全灵君
邓威
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Wuhan Wansongtang Biomedical Technology Co ltd
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Wuhan Wansongtang Biomedical Technology Co ltd
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Priority to CN202010400339.6A priority Critical patent/CN111603516A/en
Publication of CN111603516A publication Critical patent/CN111603516A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
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  • Pulmonology (AREA)
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Abstract

The invention relates to a traditional Chinese medicine composition, a pharmaceutical composition and a preparation method thereof, and application of the traditional Chinese medicine composition and the pharmaceutical composition. The raw materials for preparing the active ingredients of the pharmaceutical composition of the invention are or comprise: raw astragalus root, fried white atractylodes rhizome, ledebouriella root, basket fern, honeysuckle flower, eupatorium, dried orange peel, forsythia fruit, mulberry leaf and houttuynia cordata. The decoction for treating pneumonia is prepared by selecting, cleaning, cutting, drying, pulverizing, mixing, decocting with water to boil, and filtering. The decoction has the effects of tonifying qi, reducing pathogenic fire, diminishing inflammation, relieving cough and the like, and can effectively prevent and treat pneumonia.

Description

Decoction for preventing and treating pneumonia and preparation method
Technical Field
The invention relates to the technical field of medicines, in particular to a pharmaceutical composition for treating respiratory diseases, especially pulmonary fibrosis, and application thereof.
Background
Respiratory diseases are a large disorder that endangers humans. The diffuse interstitial lung disease is a large group of diseases characterized by diffuse alveolar unit chronic inflammation and interstitial fibrosis as main medical records, and is also called as diffuse interstitial lung disease. The diseases are manifested by progressive exertional breathlessness, restricted ventilation dysfunction with diffuse dysfunction, hypoxemia and imaging diffuse lesions of both lungs. With the progress of the disease, the function of the pulmonary alveoli-capillaries is gradually lost, and finally diffuse pulmonary fibrosis and alveoli lung are developed, so that the respiratory function is exhausted and died. The pain of the patient is effectively relieved by the comprehensive conditioning advantages of the traditional Chinese medicine; are effective in the prevention and treatment of such disorders.
Invention container
The invention aims to embody the modern processing of traditional Chinese medicines, has the functions of tonifying qi, reducing pathogenic fire, diminishing inflammation, relieving cough and the like and effectively prevents and treats pneumonia and a preparation method thereof.
The invention mainly comprises the following raw materials in parts by weight: 5-30 parts of raw astragalus membranaceus, 2-25 parts of fried bighead atractylodes rhizome, 5-30 parts of divaricate saposhnikovia root, 1-20 parts of cyrtomium rhizome, 5-60 parts of honeysuckle, 5-30 parts of fortune eupatorium herb, 1-20 parts of dried orange peel, 5-30 parts of weeping forsythia, 2-25 parts of mulberry leaf and 5-50 parts of houttuynia cordata.
The preparation method comprises the following steps:
1. selecting radix astragali, parched Atractylodis rhizoma, radix Saposhnikoviae, rhizoma Osmundae, flos Lonicerae, herba Eupatorii, pericarpium Citri Tangerinae, fructus forsythiae, folium Mori and herba Houttuyniae, cleaning, cutting, drying, pulverizing, and mixing. Thus obtaining the invention.
2. Extracting the mixed raw materials in the step 1 with pure water, decocting, separating decoction, extracting, refining, sterilizing, and making into oral preparation, spray drying or freeze drying to obtain granular capsule or solid preparation.
The raw materials used in the invention have the following functions:
raw astragalus root: astragalus root, radix astragali, sweet in nature and slightly warm in taste, enters spleen and lung meridians, and is the essential drug for invigorating qi. The clinical practice is that the raw astragalus root is used for strengthening exterior, supporting sore, inducing diuresis and the like, and the raw astragalus root is used for strengthening exterior, supporting sore, inducing diuresis and the like, which are commonly divided into 3 types by raw use, honey-fried and bran-stir-fried; radix astragali processed with honey is often used for tonifying middle-jiao and Qi; stir-baked Huang Qi is mostly used for tonifying qi and spleen.
Frying the bighead atractylodes rhizome: the rhizoma atractylodis macrocephalae has the effects of strengthening spleen and tonifying qi, eliminating dampness and promoting diuresis, suppressing sweating and preventing miscarriage. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion. Record of "medical enlightenment": the traditional Chinese medicine composition has the effects of removing dampness and benefiting dryness, regulating the middle warmer and replenishing qi, warming the middle warmer, removing dampness in the spleen and stomach, removing stomach heat, strengthening the spleen and stomach, promoting appetite, quenching thirst and preventing miscarriage.
Wind prevention: has effects of inducing perspiration, eliminating phlegm, dispelling pathogenic wind, relieving exterior syndrome, and relieving pain, and can be used for treating common cold, headache, arthralgia, and neuralgia. Dispel wind and relieve exterior syndrome, subdue dampness and stop spasm. Can be used for treating rheumatalgia, rubella, and tetanus.
Rhizoma Osmundae: can be used for treating wind-heat type common cold; rash due to tepid fever; hematemesis; hemoptysis; bleeding; hematochezia; (ii) metrorrhagia and metrostaxis; bloody dysentery; leucorrhea and intestinal parasitic diseases such as hook, ascaris and tapeworm.
Honeysuckle flower: is good product for clearing fire and removing toxicity, and can be used for treating infantile carbuncle, sore and furuncle, fever, oral diseases, etc.; it can replace tea in summer, and can be used for warm heat, eruption, acne and bloody dysentery. The stem is called honeysuckle stem and also used for medicine.
Herba Eupatorii: can be used for treating damp obstruction in middle energizer, gastric fullness, emesis, halitosis, excessive salivation, summer-heat, damp exterior syndrome, fever, listlessness, and chest distress.
Dried orange peel: can be used for treating abdominal distention, anorexia, vomiting, diarrhea, cough, and excessive phlegm.
Fructus forsythiae: clear heat, remove toxicity, dissipate nodulation and resolve swelling. It is indicated for warm heat, erysipelas, macula, superficial infection, abscess, swelling, scrofula and stranguria.
Mulberry leaf: the quality of the patients after frost is generally considered to be good after medicinal application. The mulberry leaves have the effects of dispelling wind and heat, clearing lung-heat, moistening dryness, clearing liver and improving vision. And can be used for treating wind-heat type common cold, cough due to lung heat, dizziness, headache, conjunctival congestion, and dim flower.
Houttuynia cordata: yu xing Cao is pungent in flavor and cold in nature and enters lung meridian. It has effects of clearing away heat and toxic materials, relieving swelling, treating sore, inducing diuresis, removing dampness, clearing away heat, relieving dysentery, invigorating stomach, and resolving food stagnation, and can be used for treating lung abscess, pyocutaneous disease, hemorrhoid hematochezia, and heat accumulation of spleen and stomach due to excess heat, heat toxin, dampness, and disease heat.
Application method
1. A decoction bag for preventing and treating pneumonia is prepared by adding appropriate amount of water, and decocting; one dose per day and two times per day, and 7-10 days is a treatment course.
2. A method for using solid preparation for preventing and treating pneumonia comprises putting quantitative packaged solid preparation into a cup, adding appropriate amount of hot water, dissolving the solid preparation, and taking; one bag at a time, twice a day; a treatment course is 7-10 days.
Suitable for people
Is suitable for people with upper respiratory tract infection, cough, and sore throat due to lung discomfort and other reasons.
Clinical verification shows that the effective rate of the invention for treating upper respiratory tract infection, sore throat, lung discomfort and cough reaches more than 90 percent, and the invention has the positive effects of convenient drinking and obvious treatment and health care.
Detailed description of the preferred embodiments
Example (b):
1. selecting, cleaning, cutting, drying, crushing and mixing 8 parts of raw astragalus root, 5 parts of fried bighead atractylodes rhizome, 6 parts of divaricate saposhnikovia root, 3 parts of cyrtomium rhizome, 8 parts of honeysuckle flower, 6 parts of fortune eupatorium herb, 2 parts of tangerine peel, 10 parts of weeping forsythia, 5 parts of mulberry leaf and 10 parts of heartleaf houttuynia herb to prepare a soup bag, thus obtaining the invention.
2.1) taking 6 parts of raw astragalus root, 6 parts of fried bighead atractylodes rhizome, 6 parts of divaricate saposhnikovia root, 5 parts of cyrtomium rhizome, 15 parts of honeysuckle, 8 parts of fortune eupatorium herb, 5 parts of tangerine peel, 12 parts of weeping forsythia, 6 parts of mulberry leaf and 20 parts of heartleaf houttuynia herb, adding purified water, and heating and extracting for 2 times, wherein each time lasts for 25 minutes;
2) filtering the extract liquor in the step 1, separating the green-reducing leaves by using a membrane separation device, and collecting a separation solution with the molecular weight of less than 5 ten thousand for later use;
3) and (3) separating, extracting, refining and sterilizing the decoction and decoction obtained in the step (2), and preparing the decoction into an oral preparation, and spray-drying or freeze-drying the oral preparation to prepare a granular capsule or a solid preparation.
It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. Not all embodiments are exhaustive. All obvious changes and modifications which are obvious to the technical scheme of the invention are covered by the protection scope of the invention.

Claims (2)

1. A decoction for the prophylaxis and treatment of pneumonia, comprising or consisting of: 5-30 parts of raw astragalus membranaceus, 2-25 parts of fried bighead atractylodes rhizome, 5-30 parts of divaricate saposhnikovia root, 1-20 parts of cyrtomium rhizome, 5-60 parts of honeysuckle, 5-30 parts of fortune eupatorium herb, 1-20 parts of dried orange peel, 5-30 parts of weeping forsythia, 2-25 parts of mulberry leaf and 5-50 parts of houttuynia cordata.
2. The decoction for preventing and treating pneumonia according to claim 1, which is prepared by the following method: selecting radix astragali, parched Atractylodis rhizoma, radix Saposhnikoviae, rhizoma Osmundae, flos Lonicerae, herba Eupatorii, pericarpium Citri Tangerinae, fructus forsythiae, folium Mori and herba Houttuyniae, cleaning, cutting, drying, pulverizing, and mixing;
1.) decocting the mixed materials in water according to a certain proportion, and taking the mixture twice a day, wherein a period is 7-10 days.
2) Separating, extracting, refining and sterilizing the decocted decoction obtained in the step 1, and preparing the decoction into an oral preparation, spray drying or freeze drying to prepare a granular capsule or a solid preparation.
CN202010400339.6A 2020-05-09 2020-05-09 Decoction for preventing and treating pneumonia and preparation method Pending CN111603516A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010400339.6A CN111603516A (en) 2020-05-09 2020-05-09 Decoction for preventing and treating pneumonia and preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010400339.6A CN111603516A (en) 2020-05-09 2020-05-09 Decoction for preventing and treating pneumonia and preparation method

Publications (1)

Publication Number Publication Date
CN111603516A true CN111603516A (en) 2020-09-01

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Family Applications (1)

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CN202010400339.6A Pending CN111603516A (en) 2020-05-09 2020-05-09 Decoction for preventing and treating pneumonia and preparation method

Country Status (1)

Country Link
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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张杰等: "抗新冠肺炎中药处方分析", 《HTTP://WWW.CNTCM.COM.CN/2020-03/12/CONTENT_72334.HTM》 *

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