CN111602649A - Intervertebral disc organ cryopreservation box - Google Patents
Intervertebral disc organ cryopreservation box Download PDFInfo
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- CN111602649A CN111602649A CN202010383560.5A CN202010383560A CN111602649A CN 111602649 A CN111602649 A CN 111602649A CN 202010383560 A CN202010383560 A CN 202010383560A CN 111602649 A CN111602649 A CN 111602649A
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- box body
- groove
- intervertebral disc
- fixed
- clamping
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- 210000000056 organ Anatomy 0.000 title claims abstract description 22
- 238000005138 cryopreservation Methods 0.000 title claims description 14
- 238000007710 freezing Methods 0.000 claims abstract description 11
- 230000008014 freezing Effects 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims abstract description 5
- 230000007246 mechanism Effects 0.000 claims description 18
- 239000000758 substrate Substances 0.000 claims description 15
- 230000000903 blocking effect Effects 0.000 claims description 11
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 4
- 238000004321 preservation Methods 0.000 abstract description 4
- 230000002265 prevention Effects 0.000 description 7
- 230000009471 action Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 2
- 206010061246 Intervertebral disc degeneration Diseases 0.000 description 2
- 208000008930 Low Back Pain Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000012091 fetal bovine serum Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 1
- 241000282560 Macaca mulatta Species 0.000 description 1
- 208000023178 Musculoskeletal disease Diseases 0.000 description 1
- 230000000735 allogeneic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000452 restraining effect Effects 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0268—Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09F—DISPLAYING; ADVERTISING; SIGNS; LABELS OR NAME-PLATES; SEALS
- G09F3/00—Labels, tag tickets, or similar identification or indication means; Seals; Postage or like stamps
- G09F3/02—Forms or constructions
- G09F3/0297—Forms or constructions including a machine-readable marking, e.g. a bar code
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mechanical Engineering (AREA)
- Theoretical Computer Science (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Prostheses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the field of medical instruments and discloses a freezing preservation box for intervertebral disc organs; the method comprises the following steps: the intervertebral disc device comprises a chassis, a box body for accommodating the intervertebral disc and a cover body; the upper end surface of the chassis is provided with a placing groove for accommodating the box body; the upper end of the box body is formed into an opening; the cover body covers the opening of the box body; the freezing liquid is filled in the box body; the volume of the box body is 2 to 4 times of the volume of the intervertebral disc. Compared with the prior art, the invention provides the special container for placing the intervertebral disc through the setting, and the aim of conveniently freezing and storing the intervertebral disc is fulfilled.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a freezing preservation box for intervertebral disc organs.
Background
Organ donation means that natural human volunteers before birth and donates part of the remains to the medical science cause by executives thereof after death. Or the act of donating all or part of the remains to the medical science cause by the immediate relatives after the death of the natural people who have not expressed the intention before birth. Organs, such as intervertebral discs and the like, obtained from organ donations are usually preserved by cryogenics.
Low back pain is one of the most common musculoskeletal diseases. Although many potential factors may contribute to low back pain, one known determinant is disc degeneration. The most effective treatment for severe disc degeneration is: spinal fusion and artificial disc replacement. Freshly cryopreserved intervertebral disc transplants have proven to be an effective method for the treatment of febrile disc disease in rhesus monkeys and humans.
However, in the prior art, no special container for placing the intervertebral disc exists, so that a cryopreservation box for the intervertebral disc organs needs to be provided.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a freezing preservation box for intervertebral disc organs.
The technical scheme adopted by the invention for solving the problems in the prior art is as follows:
an intervertebral disc organ cryopreservation cassette comprising: the intervertebral disc device comprises a chassis, a box body for accommodating the intervertebral disc and a cover body; the upper end surface of the chassis is provided with a placing groove for accommodating the box body; the upper end of the box body is formed into an opening; the cover body covers the opening of the box body; the freezing liquid is contained in the box body; the volume of the box body is 2 to 4 times of the volume of the intervertebral disc.
The above technical solution is further described as follows:
preferably, the device also comprises a transparent sheet and a substrate; the transparent sheet is fixed on the upper end surface of the cover body and forms a containing cavity with the cover body; the substrate is arranged in the containing cavity; an opening for the substrate to extend into or draw out of the accommodating cavity is formed between the transparent sheet and the cover body; the upper end face of the substrate is provided with a two-dimensional code which is associated with donor basic information of the intervertebral disc accommodated in the box body and the size of the intervertebral disc.
Preferably, the anti-drop device further comprises an anti-drop mechanism; the anti-falling mechanism is fixedly arranged on the chassis and used for preventing the box body from falling out of the placing groove after being placed into the placing groove.
Preferably, the drop prevention mechanism includes: the device comprises a fixed pipe, a circular ring sleeve, a connecting rod, a transparent baffle and a limiting component; the fixed pipe is arranged along the up-down direction, and the lower end of the fixed pipe is fixed on the upper end surface of the chassis and is coaxial with the chassis; the annular sleeve is slidably sleeved on the outer wall of the fixed pipe in the up-down direction; the connecting rod is horizontally arranged, and the end part of the connecting rod is fixed on the outer wall of the circular ring sleeve; the transparent baffle is horizontally arranged and fixed on one side of the connecting rod, which is far away from the annular sleeve; the limiting assembly is fixed on the fixed pipe and used for limiting the rotation of the annular sleeve after the transparent baffle plate is over against the placing groove;
after the box body is placed into the placing groove, the ring sleeve is rotated until the transparent baffle plate rotates to be opposite to the placing groove, and the limiting assembly limits the rotation of the ring sleeve so as to prevent the box body from falling out of the placing groove after being placed into the placing groove.
Preferably, the restricting assembly comprises: the clamping device comprises a through groove, a top plate, a sliding plate, a first elastic piece, a limiting rod, a first bayonet and a second bayonet;
the two through grooves are oppositely arranged on two sides of the inner wall of the fixed pipe, correspondingly penetrate through the outer wall of the fixed pipe and are arranged along the vertical direction; the top plate is fixed at the upper end of the fixed pipe; the sliding plate is connected in the fixed pipe in a sliding way along the up-down direction; the upper end of the first elastic piece is fixed at the lower end of the top plate, and the lower end of the first elastic piece is fixed at the upper end of the sliding plate; the two limiting rods are correspondingly connected into the two through grooves in a sliding manner along the up-down direction, the first ends of the limiting rods are oppositely arranged at two sides of the outer wall of the sliding plate, and the second ends of the limiting rods correspondingly penetrate through the two through grooves; the two first bayonets are oppositely arranged on two sides of the upper end surface of the circular ring sleeve and correspondingly matched with the two limiting rods in a clamping manner; the two second bayonets are oppositely arranged on the other two sides of the upper end surface of the circular ring sleeve and correspondingly matched with the two limiting rods in a clamping manner;
when the two limiting rods are correspondingly clamped at the two first clamping openings, the transparent baffle is over against the placing groove; when the two limiting rods are correspondingly clamped at the two second clamping openings, the transparent baffle is positioned beside the placing groove.
Preferably, the drop prevention mechanism includes: the sliding groove, the fan-shaped sliding groove, the sliding block, the second elastic piece and the blocking rod are arranged on the sliding block;
the sliding groove is arranged on the inner side wall of the placing groove along the vertical direction, and the upper end of the sliding groove penetrates through the upper end face of the chassis; the fan-shaped sliding groove is formed in the inner side wall of the placing groove and communicated with the side wall of the sliding groove; the sliding block is fixedly arranged on the outer wall of the box body, can slide in the sliding groove along the vertical direction, can rotate in the circumferential direction and can slide to the fan-shaped sliding groove; the second elastic piece is fixedly arranged on the bottom wall of the sliding chute; the stop rod is connected in the sliding groove in a sliding manner along the vertical direction, the lower end of the stop rod is fixed on the second elastic piece, and the upper end of the stop rod is provided with an inclined plane which is opposite to the fan-shaped sliding groove.
Preferably, the drop prevention mechanism includes: the clamping block, the clamping groove and the driving assembly; the clamping block is detachably fixed at the lower end of the box body; the clamping groove is formed in the bottom wall of the placing groove; the driving assembly is fixedly arranged in the clamping groove and drives the clamping block to be locked in the clamping groove or unlocked from the clamping groove.
Preferably, the drive assembly comprises: the clamping block and the third elastic piece; the clamping block is hooked and matched with the clamping block and can be slidably connected to the bottom wall of the clamping groove along the left-right direction; one end of the third elastic piece is fixed at the left end of the clamping block, and the other end of the third elastic piece is fixed on the left inner wall of the clamping groove; one side of the clamping block, which faces the third elastic piece, is provided with a first inclined plane, and the clamping block is provided with a second inclined plane parallel and opposite to the first inclined plane.
Preferably, the driving assembly further comprises: an elastic rope and a pull ring; a rope passing hole penetrating to the side wall of the chassis is formed in the left inner wall of the clamping groove leftwards; one end of the elastic rope is fixedly arranged on the left side of the clamping block, and the other end of the elastic rope penetrates through the rope passing hole to be connected with the pull ring.
Preferably, two sides of the upper end surface of the chassis are oppositely provided with first lifting tabs; two sides of the upper end surface of the box body are oppositely provided with second lifting tabs; the lower end of the cover body is fixedly provided with a convex block which is connected with the upper end of the inner wall of the box body through threads.
The invention has the beneficial effects that:
one is as follows: when the intervertebral disc obtained by organ donation is frozen and preserved, firstly, the cover body is opened, the freezing solution is added into the box body, and then the intervertebral disc is placed into the box body; secondly, placing the box body into a placing groove of the chassis; finally, the base plate is placed in a liquid nitrogen tank, and the intervertebral disc can be frozen and preserved. Compared with the prior art, the invention provides the special container for placing the intervertebral disc through the setting, thereby achieving the purpose of conveniently freezing and storing the intervertebral disc;
the second step is as follows: through setting for of transparency, substrate and two-dimensional code for through scanning binary code, can learn the donor basic information of the intervertebral disc of holding in the box body, like donor's blood group and intervertebral disc's size of a dimension etc. so that can follow the intervertebral disc storehouse when carrying out allogeneic intervertebral disc transplantation and accurately take the intervertebral disc, it is reserve to rewarming.
Drawings
FIG. 1 is a schematic view of a disc configuration;
FIG. 2 is a schematic view of a first perspective structure according to the first embodiment;
FIG. 3 is a schematic view of the structure of the cartridge;
FIG. 4 is a schematic structural diagram of a second perspective view according to the first embodiment;
FIG. 5 is an enlarged schematic view of the structure at A in FIG. 4;
FIG. 6 is a schematic view for showing the structure of the falling prevention mechanism according to the second embodiment;
fig. 7 is a schematic structural diagram for showing the drop preventing mechanism in the third embodiment.
The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.
Wherein, 10, a chassis; 101. a placement groove; 102. a first handle loop; 20. a box body; 30. a cover body; 301. A second handle loop; 302. a bump; 401. a transparent sheet; 402. a substrate; 501. a fixed tube; 502. a circular ring sleeve; 503. a connecting rod; 504. a transparent baffle; 505. a restraining component; 5051. a through groove; 5052. a top plate; 5053. a sliding plate; 5054. a first elastic member; 5055. a limiting rod; 5056. a first bayonet; 5057. A second bayonet; 601. a chute; 602. a fan-shaped sliding groove; 603. a slider; 604. a second elastic member; 605. a blocking lever; 6051. an inclined surface; 701. a clamping block; 702. a card slot; 7031. a clamping block; 7032. a third elastic member; 7033. an elastic cord; 7034. a pull ring; 801. a sliding groove; 802. and a slider.
Detailed Description
The technical solutions of the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments so that the inventive spirit of the present invention can be more clearly and intuitively understood.
The first embodiment is as follows:
as shown in FIG. 1, the length L of the intervertebral disc is about 60mm, the width W of the intervertebral disc is about 41mm, and the height of the intervertebral disc is about 15 mm.
Referring to fig. 2 and 3, the invention provides a freezing preservation box for intervertebral disc organs, comprising: chassis 10, box 20 and lid 30. The upper end surface of the chassis 10 is provided with a placing groove 101, and the placing groove 101 is used for accommodating the box body 20; the upper end of the box body 20 is formed as an opening; the cover body 30 covers the opening of the box body 20; the freezing liquid is contained in the box body 20. The frozen stock solution comprises: 10% DMSO (dimethyl sulfoxide), 80% DMEM (medium), and 10% FBS (fetal bovine serum).
In this embodiment, the volume of the cartridge 20 is set to 3 times the volume of the intervertebral disc; in other embodiments, the volume of the cartridge 20 may also be set to 2, 2.5, 3.5, or 4 times the volume of the disc. Preferably, 5 placing grooves 101 are circumferentially arranged by taking the axis of the chassis 10 as the center of a circle and are uniformly spaced on the upper end surface of the chassis 10, and the box bodies 20 and the placing grooves 101 are consistent in number; in other embodiments, the number of the placing slots 101 and the number of the boxes 20 can be 4.
As shown in fig. 3, in order to obtain the information related to the intervertebral disc accommodated in the case 20, the present invention comprises: a transparent sheet 401 and a substrate 402.
The transparent sheet 401 is rectangular and is arranged in a transparent manner, three edges of the transparent sheet 401 are fixed on the upper end face of the cover body 30, a containing cavity is formed between the transparent sheet 401 and the cover body 30, and the substrate 402 is arranged in the containing cavity; an opening for the substrate 402 to extend into or draw out of the cavity is formed between the other edge of the transparent sheet 401 and the cover body 30; the upper end face of the substrate 402 is provided with a two-dimensional code, the two-dimensional code is associated with donor basic information of the intervertebral disc accommodated in the box body 20 and the size of the intervertebral disc, and the donor basic information mainly refers to blood type of the donor. By scanning the two-dimensional code on the substrate 402, the donor information and the size of the disc contained in the cartridge 20 can be known.
As shown in fig. 4 and 5, in order to prevent the box 20 from falling out of the storage slot 101 after being placed in the storage slot 101, the present invention is provided with: an anti-drop mechanism. The falling prevention mechanism is fixed to the chassis 10, and is configured to prevent the box body 20 from falling out of the storage slot 101 after being placed in the storage slot 101.
The anti-falling mechanism comprises: a fixed pipe 501, a circular ring sleeve 502, a connecting rod 503, a transparent baffle 504 and a limiting component 505.
The fixed pipe 501 is arranged along the up-down direction, the lower end of the fixed pipe 501 is fixed on the upper end surface of the chassis 10, and the fixed pipe 501 and the chassis 10 are coaxially arranged; the annular sleeve 502 is sleeved on the outer wall of the fixed pipe 501 in a sliding manner along the up-down direction, and the inner diameter of the annular sleeve 502 is equal to the outer diameter of the fixed pipe 501; the connecting rods 503 are horizontally arranged, the five connecting rods 503 are uniformly arranged along the circumferential direction of the outer wall of the circular sleeve 502 at intervals, and the end parts of the five connecting rods 503 are respectively fixed on the outer wall of the circular sleeve 502; the transparent baffles 504 are horizontally arranged, and the five transparent baffles 504 are respectively fixed on one sides of the five connecting rods 503 far away from the annular sleeve 502; the vertical distance between one end of the placing groove 101 far away from the fixed pipe 501 and the fixed pipe 501 is smaller than the vertical distance between one end of the transparent baffle 504 far away from the fixed pipe 501 and the fixed pipe 501; the vertical distance between one end of the placing groove 101 close to the fixed pipe 501 and the fixed pipe 501 is greater than the vertical distance between one end of the transparent baffle 504 close to the fixed pipe 501 and the fixed pipe 501; the limiting member 505 is fixed on the fixing tube 501, and the limiting member 505 is used for limiting the rotation of the circular ring 502 after the five transparent baffles 504 respectively face the five placing grooves 101.
After the box body 20 is placed in the placing groove 101, the circular sleeve 502 is rotated until the five transparent baffles 504 correspondingly rotate to just face the five placing grooves 101, and the limiting component limits the rotation of the circular sleeve 502 so as to achieve the purpose of preventing the box body 20 from falling out of the placing groove 101 after being placed in the placing groove 101.
As shown in conjunction with fig. 4 and 5, the restriction assembly 505 includes: a through slot 5051, a top plate 5052, a sliding plate 5053, a first elastic piece 5054, a limiting rod 5055, a first bayonet 5056, and a second bayonet 5057.
The two through grooves 5051 are formed in two opposite sides of the inner wall of the fixed pipe 501, and the two through grooves 5051 correspondingly penetrate through the outer wall of the fixed pipe 501 and are arranged in the vertical direction; the top plate 5052 is fixed to the upper end of the fixed pipe 501; the sliding plate 5053 is slidably attached to the inside of the fixed pipe 501 in the up-down direction; the upper end of the first elastic member 5054 is fixed to the lower end of the top plate 5052, and the lower end of the first elastic member 5054 is fixed to the upper end of the sliding plate 5053; the two limiting rods 5055 are correspondingly connected in the two through slots 5051 in a sliding manner along the vertical direction, first ends of the two limiting rods 5055 are relatively fixed on two sides of the outer wall of the sliding plate 5053, and second ends of the two limiting rods 5055 correspondingly penetrate through the two through slots 5051; the two first bayonets 5056 are oppositely arranged on two sides of the upper end face of the circular ring sleeve 502 and correspondingly matched with the two limiting rods 5055 in a clamping manner; the two second bayonets 5057 are oppositely formed on the other two sides of the upper end surface of the circular sleeve 502 and correspondingly matched with the two limiting rods 5055 in a clamping manner. When the two limiting rods 5055 are correspondingly clamped at the two first bayonets 5056, the five transparent baffles 504 respectively face the five placing grooves 101; when the two limiting rods 5055 are correspondingly clamped at the two second bayonets 5057, the five transparent baffles 504 are respectively located beside the five placing slots 101. Preferably, the first elastic member 5054 is provided as a spring.
When the ring sleeve 502 is rotated, firstly, the two limit rods 5055 are slid upwards along the two through grooves 5051 until the lower ends of the two limit rods 5055 are spaced from the upper end of the ring sleeve 502, so as to drive the sliding plate 5053 to slide upwards along the inner wall of the fixed pipe 501, and compress the first elastic piece 5054; next, the ring sleeve 502 is rotated until the five transparent baffles 504 correspondingly rotate to face the five placement grooves 101, the limiting rods 5055 are loosened, the sliding plate 5053 is driven to slide downwards along the inner wall of the fixed pipe 501 under the action of the self-resilience force of the first elastic piece 5054, the two limiting rods 5055 are driven to slide downwards along the two through grooves 5051, and the rotation of the ring sleeve 502 can be limited until the two limiting rods 5055 are correspondingly clamped at the two first bayonets 5056.
When the ring sleeve 502 is rotated, firstly, the two limit rods 5055 are slid upwards along the two through grooves 5051 until the lower ends of the two limit rods 5055 are spaced from the upper end of the ring sleeve 502, so as to drive the sliding plate 5053 to slide upwards along the inner wall of the fixed pipe 501, and compress the first elastic piece 5054; next, the ring sleeve 502 is rotated until the five transparent baffles 504 correspondingly rotate to the side of the five placement grooves 101, the limiting rods 5055 are loosened, the sliding plate 5053 is driven to slide downwards along the inner wall of the fixed pipe 501 under the action of the self-resilience force of the first elastic piece 5054, the two limiting rods 5055 are driven to slide downwards along the two through grooves 5051, and the rotation of the ring sleeve 502 can be limited until the two limiting rods 5055 are correspondingly clamped at the two second bayonets 5057.
Preferably, the two sides of the upper end surface of the chassis 10 are oppositely provided with first lifting tabs 102 so as to move the chassis 10; the cover 30 is provided with second carrying tabs 301 at opposite sides of the upper end surface thereof to facilitate movement of the case 20.
Example two:
as shown in fig. 6, the difference from the first embodiment is that the drop prevention mechanism includes: a sliding groove 601, a sector sliding groove 602, a sliding block 603, a second elastic member 604 and a blocking rod 605.
The chute 601 is arranged on the inner side wall of the placing groove 101 along the vertical direction, and the upper end of the chute 601 penetrates the upper end surface of the chassis 10; the fan-shaped sliding groove 602 is formed in the inner side wall of the placing groove 101, and the left end of the fan-shaped sliding groove 601 is communicated with the right side wall of the sliding groove 601; the sliding block 603 is fixed on the outer wall of the box body 20, the sliding block 603 can slide in the sliding groove 601 along the up-down direction, the sliding block 603 can rotate circumferentially and slide to the fan-shaped sliding groove 602, and the sliding block 603 can slide in the fan-shaped sliding groove 602 around the axis of the placing groove 101; the second elastic piece 604 is fixed on the bottom wall of the sliding chute 601; the blocking rod 605 is slidably connected in the sliding groove 601 in the up-down direction, the lower end of the blocking rod 605 is fixed on the second elastic member 604, and the upper end of the blocking rod 605 is provided with an inclined surface 6051 facing the fan-shaped sliding groove 602.
Preferably, the upper end of the inclined surface 6051 is flush with the upper end of the fan-shaped sliding groove 602, and the lower end of the inclined surface 6051 is flush with the lower end of the fan-shaped sliding groove 602; the second elastic member 604 is provided as a spring.
When the box body 20 is placed in the placing groove 101, firstly, the sliding block 603 is aligned to the sliding groove 601, then the box body 20 is placed in the placing groove 101, the sliding block 603 is driven to slide downwards along the sliding groove 601, the sliding block 603 pushes the blocking rod 605 to slide downwards, and the blocking rod 605 compresses the second elastic piece 604; after the box body 20 is placed in the placing groove 101, the sliding block 603 is opposite to the fan-shaped sliding groove 602; then, the box body 20 is rotated to drive the sliding block 603 to slide into the fan-shaped sliding groove 602 from the sliding groove 601, and at this time, under the action of the self-resilience force of the second elastic member 604, the blocking rod 605 is driven to slide upwards until the inclined surface 6051 faces the fan-shaped sliding groove 602.
When the box body 20 is taken out of the placing groove 101, firstly, the box body 20 is rotated to drive the sliding block 603 to slide into the sliding groove 601 from the fan-shaped sliding groove 602 to rotate, in the process, the lower end of the left side of the sliding block 603 slides along the inclined surface 6051, so that the blocking rod 605 is driven to slide downwards and compress the second elastic piece 604 until the sliding block 603 slides into the sliding groove 601; next, the box body 20 is taken out upwards, and the sliding block 603 is driven to slide upwards along the sliding groove 601 and slide out from the upper end of the sliding groove 601. With the above arrangement, the box body 20 is prevented from falling out of the storage slot 101 after being placed in the storage slot 101.
In this embodiment, the same effect as that of the drop preventing mechanism in the first embodiment is achieved by the above setting.
Example three:
as shown in fig. 7, the difference from the first embodiment is that the drop prevention mechanism includes: fixture block 701, card slot 702 and drive assembly.
The fixture block 701 is hook-shaped, and the fixture block 701 is detachably fixed at the lower end of the box body 20; the clamping groove 702 is formed in the bottom wall of the placing groove 101; the driving component is fixed in the clamping groove 702, and the driving component drives the clamping block 701 to be locked in the clamping groove 702 or unlocked from the clamping groove 702.
Preferably, the upper end of the fixture block 701 is screwed on the lower end of the box body 20, and the box body 20 can be stably placed on an operating table after the fixture block 701 is screwed off from the box body 20.
The drive assembly includes: a snap-in block 7031, a third elastic member 7032, an elastic cord 7033, and a pull ring 7034.
The clamping block 7031 is in the shape of an inverted hook, the clamping block 7031 is hooked and matched with the clamping block 701, and the clamping block 7031 is connected to the bottom wall of the clamping groove 702 in a left-right sliding mode; one end of the third elastic element 7032 is fixed to the left end of the clamping block 7031, and the other end is fixed to the left inner wall of the clamping groove 702; a first inclined surface is arranged on one side of the clamping block 701 facing the third elastic part 7032, and a second inclined surface parallel to and opposite to the first inclined surface is arranged on the clamping block 7031; a rope passing hole penetrating to the side wall of the chassis 10 is formed leftwards in the left inner wall of the clamping groove 702; one end of the elastic rope 7033 is fixed on the left side of the clamping block 7031, and the other end of the elastic rope 7033 passes through the rope passing hole to be connected with the pull ring 7034.
Preferably, the third elastic member 7032 is provided as a spring; the bottom wall of the clamping groove 702 is provided with a sliding groove 801 along the left-right direction, and the lower end of the clamping block 7031 is fixed with a sliding block 802 which is connected in the sliding groove 801 in a sliding manner along the left-right direction.
When the clamping block 701 is locked, the clamping block 701 is inserted into the clamping groove 702, the first inclined surface abuts against the second inclined surface, the clamping block 701 extrudes the clamping block 7031, the first inclined surface slides along the second inclined surface to drive the clamping block 7031 to slide leftwards and compress the third elastic element 7032 until the first inclined surface is positioned below the second inclined surface, and then the clamping block 7031 is driven to slide rightwards and be hooked with the clamping block 701 under the action of self resilience force of the third elastic element 7032, so that the clamping block 701 can be locked.
When the fixture block 701 is unlocked, the pull ring 7034 is pulled leftwards, the clamping block 7031 is pulled leftwards through the elastic rope 7033 to slide until the clamping block 7031 is separated from the fixture block 701, and then the fixture block 701 can be pulled out of the clamping groove 702, so that the fixture block 701 is unlocked conveniently and easily.
Preferably, the cover 30 is fixed at a lower end thereof with a projection 302 screwed to an upper end of an inner wall of the case 20 to ensure sealability between the cover 30 and the case 20.
In the present embodiment, the same effect as that of the first embodiment is achieved by the above setting.
The above description is only a preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by using the contents of the present specification and the accompanying drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (10)
1. An intervertebral disc organ cryopreservation box, comprising: the intervertebral disc device comprises a chassis, a box body for accommodating the intervertebral disc and a cover body; the upper end surface of the chassis is provided with a placing groove for accommodating the box body; the upper end of the box body is formed into an opening; the cover body covers the opening of the box body; the freezing liquid is contained in the box body; the volume of the box body is 2 to 4 times of the volume of the intervertebral disc.
2. The cryopreservation box for intervertebral disc organs as claimed in claim 1, further comprising a transparent sheet and a substrate; the transparent sheet is fixed on the upper end surface of the cover body and forms a containing cavity with the cover body; the substrate is arranged in the containing cavity; an opening for the substrate to extend into or draw out of the accommodating cavity is formed between the transparent sheet and the cover body; the upper end face of the substrate is provided with a two-dimensional code which is associated with donor basic information of the intervertebral disc accommodated in the box body and the size of the intervertebral disc.
3. The intervertebral disc organ cryopreservation box of claim 2, further comprising a drop-prevention mechanism; the anti-falling mechanism is fixedly arranged on the chassis and used for preventing the box body from falling out of the placing groove after being placed into the placing groove.
4. The intervertebral disc organ cryopreservation box of claim 3, wherein the anti-drop mechanism comprises: the device comprises a fixed pipe, a circular ring sleeve, a connecting rod, a transparent baffle and a limiting component;
the fixed pipe is arranged along the up-down direction, and the lower end of the fixed pipe is fixed on the upper end surface of the chassis and is coaxial with the chassis; the annular sleeve is slidably sleeved on the outer wall of the fixed pipe in the up-down direction; the connecting rod is horizontally arranged, and the end part of the connecting rod is fixed on the outer wall of the circular ring sleeve; the transparent baffle is horizontally arranged and fixed on one side of the connecting rod, which is far away from the annular sleeve; the limiting assembly is fixed on the fixed pipe and used for limiting the rotation of the annular sleeve after the transparent baffle plate is over against the placing groove;
after the box body is placed into the placing groove, the ring sleeve is rotated until the transparent baffle plate rotates to be opposite to the placing groove, and the limiting assembly limits the rotation of the ring sleeve so as to prevent the box body from falling out of the placing groove after being placed into the placing groove.
5. The intervertebral disc organ cryopreservation cassette of claim 4, wherein the restriction assembly comprises: the clamping device comprises a through groove, a top plate, a sliding plate, a first elastic piece, a limiting rod, a first bayonet and a second bayonet;
the two through grooves are oppositely arranged on two sides of the inner wall of the fixed pipe, correspondingly penetrate through the outer wall of the fixed pipe and are arranged along the vertical direction; the top plate is fixed at the upper end of the fixed pipe; the sliding plate is connected in the fixed pipe in a sliding way along the up-down direction; the upper end of the first elastic piece is fixed at the lower end of the top plate, and the lower end of the first elastic piece is fixed at the upper end of the sliding plate; the two limiting rods are correspondingly connected into the two through grooves in a sliding manner along the up-down direction, the first ends of the limiting rods are oppositely arranged at two sides of the outer wall of the sliding plate, and the second ends of the limiting rods correspondingly penetrate through the two through grooves; the two first bayonets are oppositely arranged on two sides of the upper end surface of the circular ring sleeve and correspondingly matched with the two limiting rods in a clamping manner; the two second bayonets are oppositely arranged on the other two sides of the upper end surface of the circular ring sleeve and correspondingly matched with the two limiting rods in a clamping manner;
when the two limiting rods are correspondingly clamped at the two first clamping openings, the transparent baffle is over against the placing groove; when the two limiting rods are correspondingly clamped at the two second clamping openings, the transparent baffle is positioned beside the placing groove.
6. The intervertebral disc organ cryopreservation box of claim 3, wherein the anti-drop mechanism comprises: the sliding groove, the fan-shaped sliding groove, the sliding block, the second elastic piece and the blocking rod are arranged on the sliding block;
the sliding groove is arranged on the inner side wall of the placing groove along the vertical direction, and the upper end of the sliding groove penetrates through the upper end face of the chassis; the fan-shaped sliding groove is formed in the inner side wall of the placing groove and communicated with the side wall of the sliding groove; the sliding block is fixedly arranged on the outer wall of the box body, can slide in the sliding groove along the vertical direction, can rotate in the circumferential direction and can slide to the fan-shaped sliding groove; the second elastic piece is fixedly arranged on the bottom wall of the sliding chute; the stop rod is connected in the sliding groove in a sliding manner along the vertical direction, the lower end of the stop rod is fixed on the second elastic piece, and the upper end of the stop rod is provided with an inclined plane which is opposite to the fan-shaped sliding groove.
7. The intervertebral disc organ cryopreservation box of claim 3, wherein the anti-drop mechanism comprises: the clamping block, the clamping groove and the driving assembly; the clamping block is detachably fixed at the lower end of the box body; the clamping groove is formed in the bottom wall of the placing groove; the driving assembly is fixedly arranged in the clamping groove and drives the clamping block to be locked in the clamping groove or unlocked from the clamping groove.
8. The disc organ cryopreservation box of claim 7, wherein the drive assembly comprises: the clamping block and the third elastic piece; the clamping block is hooked and matched with the clamping block and can be slidably connected to the bottom wall of the clamping groove along the left-right direction; one end of the third elastic piece is fixed at the left end of the clamping block, and the other end of the third elastic piece is fixed on the left inner wall of the clamping groove; one side of the clamping block, which faces the third elastic piece, is provided with a first inclined plane, and the clamping block is provided with a second inclined plane parallel and opposite to the first inclined plane.
9. The disc organ cryopreservation cassette of claim 8, wherein the drive assembly further comprises: an elastic rope and a pull ring; a rope passing hole penetrating to the side wall of the chassis is formed in the left inner wall of the clamping groove leftwards; one end of the elastic rope is fixedly arranged on the left side of the clamping block, and the other end of the elastic rope penetrates through the rope passing hole to be connected with the pull ring.
10. The intervertebral disc organ cryopreservation box of claim 1, wherein the two sides of the upper end surface of the chassis are oppositely provided with a first lifting tab; two sides of the upper end surface of the box body are oppositely provided with second lifting tabs; the lower end of the cover body is fixedly provided with a convex block which is connected with the upper end of the inner wall of the box body through threads.
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| CN202010383560.5A CN111602649B (en) | 2020-05-08 | 2020-05-08 | Intervertebral disc organ cryopreservation box |
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| CN212589915U (en) * | 2020-05-08 | 2021-02-26 | 北京大学深圳医院 | Intervertebral disc organ cryopreservation box |
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| US20110046628A1 (en) * | 2009-08-24 | 2011-02-24 | Jamali Amir A | Method and apparatus for allograft disc transplantation |
| CN206172102U (en) * | 2016-09-29 | 2017-05-17 | 广州赛莱拉干细胞科技股份有限公司 | Novel freezing tube box |
| CN208031292U (en) * | 2017-08-31 | 2018-11-02 | 新昌县羽林街道金敏轴承厂 | A kind of scissors apparatus for placing of operation |
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|---|---|
| CN111602649B (en) | 2024-03-29 |
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