CN111601891A - 用于抑制aldh2表达的组合物和方法 - Google Patents
用于抑制aldh2表达的组合物和方法 Download PDFInfo
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- CN111601891A CN111601891A CN201980008527.XA CN201980008527A CN111601891A CN 111601891 A CN111601891 A CN 111601891A CN 201980008527 A CN201980008527 A CN 201980008527A CN 111601891 A CN111601891 A CN 111601891A
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113174438A (zh) * | 2021-06-01 | 2021-07-27 | 中国科学院城市环境研究所 | Aldh2基因多态性检测试剂盒及检测方法 |
| CN113748208A (zh) * | 2019-04-04 | 2021-12-03 | 迪克纳制药公司 | 用于抑制中枢神经系统中的基因表达的组合物和方法 |
| CN114891808A (zh) * | 2022-06-21 | 2022-08-12 | 珠海丽凡达生物技术有限公司 | 编码ALDH2多肽的mRNA分子、应用及mRNA药物 |
| WO2024000237A1 (zh) * | 2022-06-29 | 2024-01-04 | 河南省农业科学院植物营养与资源环境研究所 | Iaa-po1基因在诱导平菇原基形成和平菇生长发育抗逆中的应用 |
| CN119082043A (zh) * | 2024-10-10 | 2024-12-06 | 张家界学院 | Aldh2稳定表达的细胞系、构建方法及应用 |
| CN121294438A (zh) * | 2022-12-19 | 2026-01-09 | 昂拓生物医药有限公司 | 高级rna靶向(arnatar) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019143621A1 (en) | 2018-01-16 | 2019-07-25 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting aldh2 expression |
| WO2020226960A1 (en) | 2019-05-03 | 2020-11-12 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules with shortened sense strands |
| EP4244356A1 (en) | 2020-11-13 | 2023-09-20 | Dicerna Pharmaceuticals, Inc. | Chemical modifications for inhibiting expression of aldh2 |
| GB202218090D0 (en) | 2022-12-01 | 2023-01-18 | Proqr Therapeutics Ii Bv | Antisense oligonucleotides for the treatment of aldehyde dehydrogenase 2 deficiency |
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| KR20120005240A (ko) * | 2010-07-08 | 2012-01-16 | 한양대학교 산학협력단 | 제2알데하이드 탈수소효소의 발현을 억제하는 인공 마이크로 ｒｎａ 및 이의 이용 |
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Patent Citations (4)
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| US20030032788A1 (en) * | 1997-07-03 | 2003-02-13 | Thomas Jefferson University | Methods of inhibiting alcohol consumption |
| WO2005116265A2 (en) * | 2004-05-26 | 2005-12-08 | Wyeth | Probe arrays for expression profiling of rat genes |
| KR20120005240A (ko) * | 2010-07-08 | 2012-01-16 | 한양대학교 산학협력단 | 제2알데하이드 탈수소효소의 발현을 억제하는 인공 마이크로 ｒｎａ 및 이의 이용 |
| CN104114571A (zh) * | 2011-10-05 | 2014-10-22 | 普洛体维生物治疗公司 | 用于沉默醛脱氢酶的组合物和方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3710588A4 (en) | 2021-08-18 |
| IL275539A (en) | 2020-08-31 |
| EP3710588A1 (en) | 2020-09-23 |
| US11661603B2 (en) | 2023-05-30 |
| JP2021511042A (ja) | 2021-05-06 |
| MX2020007582A (es) | 2020-09-03 |
| WO2019143621A1 (en) | 2019-07-25 |
| KR20200109311A (ko) | 2020-09-22 |
| US20210380984A1 (en) | 2021-12-09 |
| AU2019209324A1 (en) | 2020-07-09 |
| CA3086409A1 (en) | 2019-07-25 |
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