CN111575185A - Automatic device for living cell culture - Google Patents
Automatic device for living cell culture Download PDFInfo
- Publication number
- CN111575185A CN111575185A CN202010450299.6A CN202010450299A CN111575185A CN 111575185 A CN111575185 A CN 111575185A CN 202010450299 A CN202010450299 A CN 202010450299A CN 111575185 A CN111575185 A CN 111575185A
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- Prior art keywords
- roller
- dust
- sliding plate
- cloth
- fixing rod
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- 238000004113 cell culture Methods 0.000 title claims abstract description 20
- 230000007246 mechanism Effects 0.000 claims abstract description 37
- 239000004744 fabric Substances 0.000 claims description 50
- 238000012258 culturing Methods 0.000 claims description 6
- 239000012780 transparent material Substances 0.000 claims description 3
- 239000000428 dust Substances 0.000 claims 2
- 241000894006 Bacteria Species 0.000 description 7
- 230000009471 action Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
Abstract
The invention relates to an automatic device for living cell culture, which comprises a base and an operation table, wherein the operation table is arranged on the top of the base, the front end of the operation table is provided with an observation plate, an operation window is arranged between the observation plate and the base, the upper end and the lower end of the operation window are respectively provided with a guide rail, two sliding plates are arranged in the operation window and are in sliding connection with the guide rails, the center of each sliding plate is provided with an operation opening, the left end and the right end of the operation window are respectively provided with a first dustproof mechanism, the sliding plates are respectively connected with the first dustproof mechanisms on the same side, and the sliding plates are connected through a second dustproof mechanism. Improve the success rate of cell culture.
Description
Technical Field
The invention belongs to the technical field of cell culture, and particularly relates to an automatic device for living cell culture.
Background
Cell culture refers to a method of simulating in vivo environment (sterile, proper temperature, pH value, certain nutritional conditions, etc.) in vitro to enable the cells to survive, grow, reproduce and maintain the main structure and function. The super clean bench is one of the main facilities for cell culture, is a universal local purifying device for single person operation, and the airflow forms vertical laminar flow and horizontal laminar flow, so that it can create local high-cleanliness air environment, and is an ideal special device for scientific research, pharmacy, medical health and other industries. The superclean bench can be equipped with the operation window, makes things convenient for the experimenter to stretch into the superclean bench with both hands and operates, and the operation window is open usually, and this has just led to outside air and bacterium to enter into the superclean bench in, causes certain influence to internal environment, leads to the cell culture failure easily.
Disclosure of Invention
Therefore, the invention provides the automatic device for living cell culture, which ensures that both hands can operate flexibly, improves the difficulty of external bacteria entering the operation table, keeps the cleanness inside the operation table, reduces the influence of the internal environment of the operation table on cell culture, and improves the success rate of cell culture.
The technical scheme of the invention is realized as follows:
the invention provides an automatic device for culturing living cells, which comprises a base and an operating platform, wherein the operating platform is arranged at the top of the base, and the automatic device is characterized in that an observation plate is arranged at the front end of the operating platform, an operation window is arranged between the observation plate and the base, guide rails are respectively arranged at the upper end and the lower end of the operation window, two sliding plates are arranged in the operation window, the sliding plates are slidably connected with the guide rails, an operation opening is arranged at the center of each sliding plate, first dustproof mechanisms are respectively arranged at the left end and the right end of the operation window, the sliding plates are respectively connected with the first dustproof mechanisms at the same side, and the sliding plates are connected through second dustproof mechanisms.
Preferably, the first dustproof mechanism comprises a first fixed rod, a first roller, first dustproof cloth and a telescopic mechanism, the first fixed rod is installed at two ends of the operation window, the first roller is installed at one end, located on one side of the first fixed rod, of the sliding plate, one end of the first dustproof cloth is fixedly connected with the first fixed rod, the other end of the first dustproof cloth is connected to the first roller in a wound mode, and the first roller is connected with the telescopic mechanism.
Preferably, the telescopic mechanism comprises a rectangular rack and a rotating wheel, the rotating wheel is arranged at the upper end and the lower end of the first roller, the rotating wheel is coaxially connected with the first roller, the rack is arranged on one side, away from the operation window, of the guide rail, and the rotating wheel is meshed with the rack.
Preferably, the second dustproof mechanism comprises a second fixing rod, a second roller, second dustproof cloth and a torsion spring, the second fixing rod is arranged at the right end of the sliding plate on the left side, the second roller is arranged at the left end of the sliding plate on the right side, one end of the second dustproof cloth is fixedly connected with the second fixing rod, the other end of the second dustproof cloth is wound on the second roller, the torsion spring is arranged at the upper end and the lower end of the second roller, and the second roller is connected with the inner wall of the sliding plate through the torsion spring.
Preferably, the first dustproof cloth and the second dustproof cloth are made of transparent materials.
Preferably, an opening plate is arranged on one side of the operating platform, and one side of the opening plate is hinged to the operating platform.
Preferably, an elastic ring is installed in the operation opening, and the elastic ring is connected with the operation opening through dust-free cloth.
Preferably, the sliding plate is provided with a shielding cloth at the upper part thereof for shielding the operation opening, and the upper side of the shielding cloth is fixedly connected with the sliding plate.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides an automatic device for living cell culture, which drives a sliding plate to slide left and right through an arm, does not influence an operator to take instruments left and right, ensures that both hands can operate flexibly, greatly reduces the flow passage inside and outside an operation table through a first dustproof mechanism and a second dustproof mechanism, improves the difficulty of external bacteria entering the operation table, keeps the cleanness inside the operation table, reduces the influence of the internal environment of the operation table on cell culture, and improves the success rate of cell culture.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only preferred embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without inventive exercise.
Fig. 1 is a schematic front structural view of a first embodiment of the present invention;
FIG. 2 is a schematic view of an internal structure of an operating window according to an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of a first dustproof mechanism and a second dustproof mechanism according to a first embodiment of the present invention;
FIG. 4 is a schematic side view of a second embodiment of the present invention;
FIG. 5 is a schematic structural diagram of an elastic ring according to a second embodiment of the present invention;
fig. 6 is a schematic structural view of a shielding cloth according to a second embodiment of the present invention.
In the figure, 1 base, 2 operation panel, 3 observation panel, 4 operation windows, 5 guide rails, 6 sliding plates, 7 operation openings, 8 first fixed rods, 9 first rollers, 10 first dustproof cloth, 11 racks, 12 rotating wheels, 13 second fixed rods, 14 second rollers, 15 second dustproof cloth, 16 torsion springs, 17 opening plates, 18 elastic rings, 19 dust-free cloth and 20 shielding cloth.
Detailed Description
In order to better understand the technical content of the invention, specific embodiments are provided below, and the invention is further described with reference to the accompanying drawings.
Example one
Referring to fig. 1 to 3, the present invention provides a mobile fire fighting equipment detection device, including a base 1 and an operation table 2, the operating platform 2 is arranged on the top of the base 1, a transparent observation plate 3 is arranged at the front end of the operating platform 2, an operation window 4 is arranged between the observation plate 3 and the base 1, the middle part of the operation window 4 is hollowed, the upper end and the lower end of the operation window 4 are respectively provided with a guide rail 5, two sliding plates 6 are arranged in the operation window 4, the sliding plate 6 is connected with the guide rail 5 in a sliding way, the center of the sliding plate 6 is provided with an operation opening 7, the left end and the right end of the operation window 4 are respectively provided with a first dustproof mechanism, the sliding plates 6 are respectively connected with the first dustproof mechanisms at the same side, the sliding plates 6 are connected through a second dustproof mechanism, the working window 4 is surrounded and protected by the first dust-proof mechanism and the second dust-proof mechanism.
When in use, both hands are extended into the operation table 2 from the operation opening 7, cells are cultured by observing the observation plate 3, the sliding plate 6 is driven by the arm to slide left and right, so that instruments at other positions in the operating platform 2 can be conveniently taken out, when the sliding plate 6 moves to the same side, the first dust-proof mechanism protects the operation window 4, when the sliding plates 6 on the left and right sides move freely in opposite directions, the second dust-proof mechanism protects the space between the sliding plates 6, the instrument of taking about not influencing operating personnel, when guaranteeing that both hands can operate in a flexible way, has reduced the inside and outside circulation passageway of operation panel 2 greatly, has improved the degree of difficulty that outside bacterium entered into in the operation panel 2, keeps the inside cleanliness of operation panel 2, has reduced the influence of 2 internal environment of operation panel to cell culture, improves cell culture's success rate.
The first dustproof mechanism comprises a first fixed rod 8, a first roller 9, a first dustproof cloth 10 and a telescopic mechanism, the first fixed rod 8 is arranged at two ends of the operation window 4, the first roller 9 is arranged at one end of the sliding plate 6 positioned at one side of the first fixed rod 8, the first roller 9 is arranged at the left end of the left sliding plate 6 and the right end of the right sliding plate 6, one end of the first dustproof cloth 10 is fixedly connected with the first fixed rod 8, the other end of the first dustproof cloth 10 is connected on the first roller 9 in a winding way, the first fixed rod 8 at the left side is connected with the first roller 9 at the left side through the first dustproof cloth 10, the first fixed rod 8 at the right side is connected with the first roller 9 at the right side through the first dustproof cloth 10, the first roller 9 is connected with the telescopic mechanism, when the sliding plate 6 slides to the left, the first roller 9 at the left side is driven by the telescopic mechanism, the first dustproof cloth 10 on the left side is rolled; the first roller 9 on the right side is driven by the telescopic mechanism to release the first dustproof cloth 10 on the right side; in a similar way, the sliding plate 6 is also the same when sliding rightwards, so that the operation window 4 is protected by the first dustproof cloth 10 while the left and right movement and flexible operation of both hands are ensured, and the difficulty of entering the operation table 2 by external bacteria is improved.
The telescopic mechanism comprises a rectangular rack 11 and a rotating wheel 12, the rotating wheel 12 is installed at the upper end and the lower end of the first roller 9, the rotating wheel 12 is coaxially connected with the first roller 9, the rack 11 is installed at one side, far away from the operation window 4, of the guide rail 5, the rotating wheel 12 is meshed with the rack 11, the rack 11 is located in front of the rotating wheel 12, when the sliding plate 6 slides leftwards, the rotating wheel 12 rotates anticlockwise under the action of the rack 11, the first roller 9 on the left side winds up the first dustproof cloth 10 on the left side, and the first roller 9 on the right side releases the first dustproof cloth 10 on the right side; when the sliding plate 6 slides rightwards, the rotating wheel 12 rotates clockwise under the action of the rack 11, the first dustproof cloth 10 on the left side is released by the first roller 9 on the left side, and the first dustproof cloth 10 on the right side is rolled up by the first roller 9 on the right side.
The second dust-proof mechanism comprises a second fixing rod 13, a second roller 14, a second dust-proof cloth 15 and a torsion spring 16, the second fixing rod 13 is installed at the right end of the sliding plate 6 on the left side, the second roller 14 is installed at the left end of the sliding plate 6 on the right side, one end of the second dust-proof cloth 15 is fixedly connected with the second fixing rod 13, the other end of the second dust-proof cloth 15 is connected to the second roller 14 in a winding manner, the torsion spring 16 is installed at the upper end and the lower end of the second roller 14, the second roller 14 is connected with the inner wall of the sliding plate 6 through the torsion spring 16, when two hands need to move in opposite directions, the sliding plate 6 on the left side pulls the second dust-proof cloth 15 to be released outwards through the second fixing rod 13, and the space between the; when the two hands get close again, the second roller 14 is driven by the torsion spring 16 to wind the second dustproof cloth 15.
The first dustproof cloth 10 and the second dustproof cloth 15 are made of transparent materials, and visibility is improved.
Example two
Referring to fig. 4 to 6, the present embodiment is different from the first embodiment in that an opening and closing plate 17 is disposed on one side of the console 2, one side of the opening and closing plate 17 is hinged to the console 2, a desired instrument can be placed in the console 2 by opening the opening and closing plate 17 after the placement is completed.
Install elasticity circle 18 in the operation mouth 7, connect through dustless cloth 19 between elasticity circle 18 and the operation mouth 7, stretch into under the condition that does not influence both hands through elasticity circle 18, reduce the convection space of operation mouth 7 and external world, improve the degree of difficulty that outside bacterium enters into in the operation panel 2.
The upper part of the sliding plate 6 is provided with shielding cloth 20 for shielding the operation opening 7, the upper side of the shielding cloth 20 is fixedly connected with the sliding plate 6, when the operation table 2 is not used, the lower part of the shielding cloth 20 shields and seals the operation opening 7, and the possibility that bacteria enter the operation table 2 from the operation opening 7 when the equipment is idle is greatly reduced.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (8)
1. The utility model provides an automation equipment for living body cell culture, includes base and operation panel, the operation panel is installed the top of base, its characterized in that, the front end of operation panel is equipped with observes the board, be equipped with the operation window between observation board and the base, the upper and lower both ends of operation window are equipped with the guide rail respectively, be equipped with two sliding plates in the operation window, the sliding plate with guide rail sliding connection, the sliding plate center is equipped with the operation mouth, both ends all are equipped with first dustproof mechanism about the operation window, the sliding plate is connected with the first dustproof mechanism of homonymy respectively, connect through the dustproof mechanism of second between the sliding plate.
2. The automated apparatus for culturing living cells of claim 1, wherein the first dust-proof mechanism comprises a first fixing rod, a first roller, a first dust-proof cloth and a telescopic mechanism, the first fixing rod is installed at two ends of the operation window, the first roller is installed at one end of the sliding plate on one side of the first fixing rod, one end of the first dust-proof cloth is fixedly connected with the first fixing rod, the other end of the first dust-proof cloth is wound on the first roller, and the first roller is connected with the telescopic mechanism.
3. The automated apparatus for living cell culture according to claim 2, wherein the telescoping mechanism comprises a rectangular rack and a rotating wheel, the rotating wheel is installed at the upper end and the lower end of the first roller, the rotating wheel is coaxially connected with the first roller, the rack is installed at the side of the guide rail far away from the operation window, and the rotating wheel is meshed with the rack.
4. The automated apparatus for culturing living cells of claim 3, wherein the second dust-proof mechanism comprises a second fixing rod, a second roller, a second dust-proof cloth and a torsion spring, the second fixing rod is installed at the right end of the sliding plate at the left side, the second roller is installed at the left end of the sliding plate at the right side, one end of the second dust-proof cloth is fixedly connected with the second fixing rod, the other end of the second dust-proof cloth is wound on the second roller, the torsion spring is installed at the upper end and the lower end of the second roller, and the second roller is connected with the inner wall of the sliding plate through the torsion spring.
5. The automated apparatus for culturing living cells of claim 1, wherein the first dust cloth and the second dust cloth are made of transparent material.
6. An automated apparatus for culturing living cells according to claim 1, wherein a side of the operation table is provided with a cut-open plate, and a side of the cut-open plate is hinged with the operation table.
7. The automated apparatus for culturing living cells of claim 1, wherein an elastic ring is installed in the operation port, and the elastic ring and the operation port are connected through a dust-free cloth.
8. The automated apparatus for living cell culture according to claim 1, wherein a shielding cloth for shielding the operation opening is installed on an upper portion of the sliding plate, and an upper side of the shielding cloth is fixedly connected to the sliding plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010450299.6A CN111575185A (en) | 2020-05-25 | 2020-05-25 | Automatic device for living cell culture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010450299.6A CN111575185A (en) | 2020-05-25 | 2020-05-25 | Automatic device for living cell culture |
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| Publication Number | Publication Date |
|---|---|
| CN111575185A true CN111575185A (en) | 2020-08-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010450299.6A Pending CN111575185A (en) | 2020-05-25 | 2020-05-25 | Automatic device for living cell culture |
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| Country | Link |
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| CN (1) | CN111575185A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1300195A1 (en) * | 2000-05-22 | 2003-04-09 | Nara Machinery Co., Ltd. | Powder processing unit |
| CN205495606U (en) * | 2015-11-19 | 2016-08-24 | 鼎正动物药业（天津）有限公司 | Experimental ultra -clean control box of biology |
| CN206911399U (en) * | 2017-04-13 | 2018-01-23 | 广州市品然生物科技有限公司 | A kind of new super-clean bench |
| CN207463264U (en) * | 2017-10-25 | 2018-06-08 | 青州市亚泰农业科技有限公司 | A kind of novel asepsis operation console |
| WO2019169631A1 (en) * | 2018-03-09 | 2019-09-12 | 南通大学 | Test tube, storage tray, syringe carrier, and sterilization tray having magnetic base for using on super clean bench |
| CN216936123U (en) * | 2021-12-31 | 2022-07-12 | 巴马奥比特生命科技研究有限公司 | A superclean bench for stem cell handles |
-
2020
- 2020-05-25 CN CN202010450299.6A patent/CN111575185A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1300195A1 (en) * | 2000-05-22 | 2003-04-09 | Nara Machinery Co., Ltd. | Powder processing unit |
| CN205495606U (en) * | 2015-11-19 | 2016-08-24 | 鼎正动物药业（天津）有限公司 | Experimental ultra -clean control box of biology |
| CN206911399U (en) * | 2017-04-13 | 2018-01-23 | 广州市品然生物科技有限公司 | A kind of new super-clean bench |
| CN207463264U (en) * | 2017-10-25 | 2018-06-08 | 青州市亚泰农业科技有限公司 | A kind of novel asepsis operation console |
| WO2019169631A1 (en) * | 2018-03-09 | 2019-09-12 | 南通大学 | Test tube, storage tray, syringe carrier, and sterilization tray having magnetic base for using on super clean bench |
| CN216936123U (en) * | 2021-12-31 | 2022-07-12 | 巴马奥比特生命科技研究有限公司 | A superclean bench for stem cell handles |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20200922 Address after: 511500 the third card shop on the first floor, No. 251, xibailing village, Shiling village committee, Longtang Town, Qingyuan City, Guangdong Province Applicant after: Guangdong kangdun Bioengineering Technology Co.,Ltd. Address before: 571157 building 196, science and technology innovation center, mei'an science and technology new town, Xiuying street, Xiuying District, Haikou City, Hainan Province Applicant before: Haikou health Island Biotechnology Co.,Ltd. |
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Effective date of registration: 20210422 Address after: 2806, foreign trade group building, 239 Zhongxing Road, Chengdong community, Dongmen street, Luohu District, Shenzhen, Guangdong 518000 Applicant after: Guangdong kangdun Innovation Industry Group Co.,Ltd. Address before: 511500 the third card shop on the first floor, No. 251, xibailing village, Shiling village committee, Longtang Town, Qingyuan City, Guangdong Province Applicant before: Guangdong kangdun Bioengineering Technology Co.,Ltd. |
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Application publication date: 20200825 |
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| RJ01 | Rejection of invention patent application after publication |