CN111548904B - Optical device for gene sequencing - Google Patents

Optical device for gene sequencing Download PDF

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Publication number
CN111548904B
CN111548904B CN202010316733.1A CN202010316733A CN111548904B CN 111548904 B CN111548904 B CN 111548904B CN 202010316733 A CN202010316733 A CN 202010316733A CN 111548904 B CN111548904 B CN 111548904B
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groove
shooting
fixed
plate
carrying
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CN111548904A (en
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雍金贵
施荣辉
黄晓峰
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General Biology Anhui Co ltd
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General Biology Anhui Co ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B13/00—Viewfinders; Focusing aids for cameras; Means for focusing for cameras; Autofocus systems for cameras
    • G03B13/32—Means for focusing
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B15/00—Special procedures for taking photographs; Apparatus therefor
    • G03B15/02—Illuminating scene
    • G03B15/03—Combinations of cameras with lighting apparatus; Flash units

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
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  • Immunology (AREA)
  • Biotechnology (AREA)
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  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses an optical device for gene sequencing, which comprises a base, wherein a shooting groove is formed in the center of the upper surface of the base, a conveying groove is formed below the shooting groove, a carrying plate is arranged in the conveying groove, a shell is fixed on the upper surface of the base, and a shooting lens is arranged in the shell; through carrier bottom plate and fixed plate cooperation use, fix the gene chip in carrying the thing inslot, when having prevented carrying the thing board at the conveyer trough internal motion, lead to the gene chip to take place the skew and then influenced the operation of shooing, carry the use of thing board and make at the equipment during operation, the operator can use new year thing board to load the gene chip, and then reduced the preparation time of work of shooing, the efficiency of work of shooing has been promoted, the casing makes the shooting of gene chip go on under sealed environment, prevent that external factor from interfering to cause the result of shooing to receive the influence, and the device maintenance cost is low, greatly reduced the cost input of gene sequencing.

Description

Optical device for gene sequencing
Technical Field
The invention belongs to the gene detection technology, and particularly relates to an optical device for gene sequencing.
Background
Gene sequencing is a novel gene detection technology, can analyze and determine the complete sequence of genes from blood or saliva, predicts the possibility of suffering from various diseases, has reasonable behavior characteristics and behaviors, can lock individual lesion genes, prevents and treats the individual lesion genes in advance, and is becoming a scientific technology for promoting the rapid development of human society in this century;
at present, when carrying out DNA fluorescence quantitative analysis of gene sequencing, need carry out continuous operation of shooing to detecting sample through camera equipment, at present when shooing the operation, all often carry out the operation of shooing through the optical device that the structure is relatively complicated, traditional optical device operation maintenance cost is high, and then make gene sequencing cost input big, and traditional optical device, when shooing in succession the chip, only can carry out single shooting, the shooting efficiency to many gene chips is low, and the preparation time of the operation of shooing is longer, partial optical device easily receives external factor influence for the result of shooing is relatively poor.
Disclosure of Invention
The invention aims to provide an optical device for gene sequencing.
The invention aims to solve the technical problems:
the traditional optical device is high in operation and maintenance cost, so that the gene sequencing cost is high, and the traditional optical device can only singly photograph when continuously photographing the chip, has low photographing efficiency for more gene chips, is long in preparation time for photographing operation, is easily influenced by external factors, and is poor in photographing result.
The aim of the invention can be achieved by the following technical scheme:
an optical device for gene sequencing comprises a base, a shooting groove is arranged in the center of the upper surface of the base, a conveying groove is arranged below the shooting groove, a carrying object is arranged in the conveying groove, two oppositely arranged upper rotating shafts are arranged at the upper end of the base, the upper rotating shafts are rotationally connected with the base, upper driving rollers are fixed at two ends of the upper rotating shafts, an upper driving belt is arranged between the two oppositely arranged upper driving rollers, an upper driving gear is fixed at one end of one upper rotating shaft, two oppositely arranged lower rotating shafts are arranged at the lower end of the inner part of the base, the lower rotating shafts are rotationally connected with the base, lower driving rollers are fixed at two ends of the lower rotating shafts, a lower driving belt is arranged between the two oppositely arranged lower driving rollers, one end of one lower rotating shaft is fixedly provided with a lower driving gear which is meshed with the upper driving gear, the device comprises a base, a first motor, a shell, a second motor, a screw rod, a limiting slide rod, a bearing column, a screw block, an auxiliary light source, a plurality of shooting lenses, two auxiliary light sources, a limiting slide rod and a plurality of limiting slide rods, wherein the first motor is fixedly arranged on one side of the base, the output end of the first motor is fixedly connected with a lower rotating shaft, the upper surface of the base is fixedly provided with the shell, the center of the top end of the outer part of the shell is fixedly provided with the second motor, the screw rod penetrates through the top wall of the shell, the screw rod is rotationally connected with the top wall of the shell, two oppositely arranged slide grooves are formed in the inner wall of the shell, the bearing column is sleeved on the screw rod, the screw block is arranged in the bearing column, the screw block is in screw connection with the screw rod, the bottom end of the bearing column is fixedly provided with the bearing table, the lower surface of the bearing table is fixedly provided with the shooting lenses, two oppositely arranged auxiliary light sources are arranged on two sides of the shooting lenses, the auxiliary light sources are fixedly connected with the limiting slide rod, and the limiting slide rod is matched with the slide grooves;
the utility model provides a carry thing board, carry the upper surface of thing bottom plate to open and have first spread groove, the lateral wall top of first spread groove is opened there are two second spread grooves that set up in opposition, be equipped with the fixed block on the lateral wall of second spread groove, fixed block and the lateral wall sliding connection of second spread groove, the one end that the second spread groove was kept away from to the fixed block is fixed with the telescopic link, telescopic link and the inner wall fixed connection who carries the thing bottom plate, cup jointed the spring on the telescopic link, the both ends of spring are kept away from the one end and the inner wall fixed connection who carries the thing bottom plate with the fixed block respectively, the upper surface that carries the thing bottom plate is equipped with a plurality of rows of evenly distributed's year thing grooves, carry thing bottom plate top to be equipped with the fixed plate, the both sides of fixed plate are fixed with the curb plate, it has the second fixed groove to open on the lateral wall of curb plate, second fixed groove cooperatees with the fixed block, open a plurality of shooting holes on the fixed plate, shooting hole and year thing groove one-to be fixed with two opposite fastening plates that set up below, the fastening plate keeps away from the lateral wall that the shooting hole and carries the thing groove laminating mutually.
Further, the conveyer trough with shoot the inside intercommunication of groove, the conveyer trough runs through the base, go up the top that the pivot is located the conveyer trough, the conveyer trough is located the both sides of shooting the groove, the lower pivot is located the below of conveyer trough, the upper pivot and the lower pivot that are located same one side are on same horizontal vertical line.
Further, the lower surface of last drive belt be located the inside of conveyer trough, go up the drive belt and be located the both sides of shooting the groove, the upper surface of lower drive belt is located the inside of conveyer trough, the lower drive belt is located the both sides of shooting the groove, go up drive gear and lower drive gear and be located the inside of base.
Further, the outside top of casing be equipped with the display screen, shooting camera lens and display screen electrical connection, the bottom both sides of screw rod are fixed with two stopper that set up in opposition, the stopper is located the inside of casing.
Further, the bearing column is located inside the shell, two oppositely arranged connecting rods are fixed to two sides of the screw block, the ends of the connecting rods are fixedly connected with the inner wall of the bearing column, and the number of shooting lenses corresponds to that of each row of shooting holes one by one.
Further, the article carrying groove be located the inside of first spread groove, the lateral wall of first spread groove and fixed plate is laminated mutually, the second spread groove is laminated mutually with the lateral wall of curb plate, the diapire of second spread groove is opened there is first fixed slot, the lower fixed surface of curb plate has the gag lever post, the gag lever post cooperatees with first fixed slot, the bottom mounting of fastening plate has rubber gasket, the one end that the fixed block is close to the second spread groove is the sphere.
Further, the operation steps of the optical device for gene sequencing are as follows:
step one: placing a gene chip to be photographed in a carrying groove, covering a fixing plate on the carrying plate, enabling a first connecting groove to be attached to the side wall of the fixing plate, enabling a second connecting groove to be attached to the side wall of a side plate, enabling a fixing block to be attached to the second fixing groove, enabling a limiting rod to be attached to the first fixing groove, enabling the fixing plate to be installed with a carrying bottom plate, enabling a rubber gasket to be attached to the gene chip, and enabling the gene chip to be fixed inside the carrying groove;
step two: starting a first motor, wherein the first motor drives a lower rotating shaft to rotate, the lower rotating shaft drives a lower driving roller and a lower driving gear to rotate, the lower driving roller drives a lower driving belt to move, the lower driving gear drives an upper driving gear to rotate, the upper driving gear drives an upper rotating shaft to rotate, the upper rotating shaft drives an upper driving roller to rotate, and the upper driving roller drives an upper driving belt to move;
step three: the carrying plate is matched with the conveying groove in a plugging manner, so that the upper transmission belt is attached to the upper surface of the carrying bottom plate, and the lower transmission belt is attached to the lower surface of the carrying bottom plate, so that the carrying plate moves towards the inside of the conveying groove;
step four: when the object carrying groove moves to the inside of the shooting groove, and meanwhile, the object carrying groove is positioned under the shooting machine head, continuous shooting is completed, and the object carrying plate continues to move until all the gene chips complete continuous shooting.
The invention has the beneficial effects that:
through carrier bottom plate and fixed plate cooperation use, fix the gene chip in carrying the thing inslot and prevented that the carrier plate from moving at the conveyer trough inside, lead to the gene chip to take place the skew and then influenced the operation of shooing, carrying the use of thing board makes, when equipment works, the operator can use new carrier plate to load the gene chip, and then reduce the preparation time of work of shooing, the efficiency of work of shooing has been promoted, the casing makes the shooting of gene chip go on under sealed environment, prevent that external factor from interfering to cause the result of shooing to receive the influence, auxiliary light source adjusts the light source of shooting environment, bear the post and the cooperation of screw rod makes the focus of taking the camera lens can be adjusted, and then guaranteed the image definition of shooing, and the device maintenance cost is low, greatly reduced the cost input of gene sequencing.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of an optical device for gene sequencing according to the present invention;
FIG. 2 is a side view of a susceptor in an optical device for gene sequencing according to the present invention;
FIG. 3 is a top view of a susceptor in an optical device for gene sequencing according to the present invention;
FIG. 4 is a top view of a carrier plate in an optical device for gene sequencing according to the present invention;
FIG. 5 is a schematic diagram showing a side view of a carrier plate in an optical device for gene sequencing according to the present invention.
In the figure: 1. a base; 11. a shooting groove; 12. a conveying trough; 13. an upper rotating shaft; 131. an upper driving roller; 132. an upper belt; 133. an upper transmission gear; 14. a lower rotating shaft; 141. a lower driving roller; 142. a lower belt; 143. a lower transmission gear; 15. a first motor; 2. a housing; 21. a second motor; 22. a screw; 23. a limiting block; 24. a chute; 3. a load-bearing column; 31. a screw block; 32. a connecting rod; 33. a carrying platform; 34. a photographing lens; 35. an auxiliary light source; 36. a limit slide bar; 4. a carrying plate; 41. a loading bottom plate; 411. a first connection groove; 412. a carrying groove; 413. a second connecting groove; 414. a first fixing groove; 415. a fixed block; 416. a telescopic rod; 417. a spring; 42. a fixing plate; 421. a side plate; 4211. a second fixing groove; 4212. a limit rod; 422. a photographing hole; 423. a fastening plate; 4231. rubber gaskets.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to FIG. 1, the present invention is an optical device for gene sequencing, comprising a base 1, a shooting slot 11 is provided at the center of the upper surface of the base 1, a conveying slot 12 is provided below the shooting slot 11, a carrying plate 4 is provided inside the conveying slot 12, two oppositely disposed upper rotating shafts 13 are provided at the upper end of the base 1, the upper rotating shafts 13 are rotatably connected with the base 1, upper driving rollers 131 are fixed at two ends of the upper rotating shafts 13, an upper driving belt 132 is installed between the two oppositely disposed upper driving rollers 131, an upper driving gear 133 is fixed at one end of one of the upper rotating shafts 13, two oppositely disposed lower rotating shafts 14 are provided at the lower end of the base 1, the lower rotating shafts 14 are rotatably connected with the base 1, lower driving rollers 141 are fixed at two ends of the lower rotating shafts 14, a lower driving belt 142 is installed between the two oppositely disposed lower driving rollers 141, one end of one of the lower rotating shafts 14 is fixed with a lower driving gear 143, the lower transmission gear 143 is meshed with the upper transmission gear 133, a first motor 15 is fixed on one side of the base 1, the output end of the first motor 15 is fixedly connected with the lower rotating shaft 14, a shell 2 is fixed on the upper surface of the base 1, a second motor 21 is fixed at the center of the top end of the outer part of the shell 2, a screw rod 22 is fixed on the output end of the second motor 21, the screw rod 22 penetrates through the top wall of the shell 2, the screw rod 22 is rotationally connected with the top wall of the shell 2, two oppositely arranged sliding grooves 24 are formed in the inner wall of the shell 2, a bearing column 3 is sleeved on the screw rod 22, a screw block 31 is arranged in the bearing column 3, the screw block 31 is in screw connection with the screw rod 22, a bearing table 33 is fixed at the bottom end of the bearing column 3, a plurality of shooting lenses 34 are fixed on the lower surface of the bearing table 33, two oppositely arranged auxiliary light sources 35 are arranged on two sides of the shooting lenses 34, the auxiliary light sources 35 are fixedly connected with the bearing table 33, two limiting slide bars 36 which are oppositely arranged are fixed on the side wall of the bearing column 3, and the limiting slide bars 36 are matched with the slide grooves 24;
the object carrying plate 4 comprises an object carrying bottom plate 41, a first connecting groove 411 is formed in the upper surface of the object carrying bottom plate 41, two second connecting grooves 413 which are oppositely arranged are formed in the top of the side wall of the first connecting groove 411, fixing blocks 415 are arranged on the side walls of the second connecting grooves 413, the fixing blocks 415 are slidably connected with the side walls of the second connecting grooves 413, a telescopic rod 416 is fixed at one end, far away from the second connecting grooves 413, of each fixing block 415, the telescopic rod 416 is fixedly connected with the inner wall of the object carrying bottom plate 41, springs 417 are sleeved on the telescopic rod 416, two ends of each spring 417 are fixedly connected with one end, far away from the second connecting grooves 413, of each fixing block 415 and the inner wall of the object carrying bottom plate 41 respectively, a plurality of rows of object carrying grooves 412 which are evenly distributed are formed in the upper surface of the object carrying bottom plate 41, fixing plates 42 are arranged above the object carrying bottom plate 41, side plates 421 are fixed on two sides of each fixing plate 42, a plurality of photographing holes 422 are formed in the side walls of each fixing plate 421, the photographing holes 422 are correspondingly arranged on the fixing plates 42, the photographing holes 422 are correspondingly arranged on the side walls of the fixing plates 422, and the two opposite side walls of the photographing holes 422 are correspondingly arranged on the side walls of the fixing plates 422, and the photographing holes 422 are correspondingly arranged on the side walls of the fixing plates 422.
The conveying groove 12 is communicated with the inside of the shooting groove 11, the conveying groove 12 penetrates through the base 1, the upper rotating shaft 13 is located above the conveying groove 12, the conveying groove 12 is located on two sides of the shooting groove 11, the lower rotating shaft 14 is located below the conveying groove 12, and the upper rotating shaft 13 and the lower rotating shaft 14 located on the same side are located on the same horizontal vertical line.
The lower surface of the upper driving belt 132 is located inside the conveying groove 12, the upper driving belt 132 is located at two sides of the photographing groove 11, the upper surface of the lower driving belt 142 is located inside the conveying groove 12, the lower driving belt 142 is located at two sides of the photographing groove 11, and the upper driving gear 133 and the lower driving gear 143 are located inside the base 1.
The outside top of casing 2 be equipped with the display screen, shooting lens 34 and display screen electrical connection, the bottom both sides of screw rod 22 are fixed with two stopper 23 that set up in opposition, stopper 23 is located the inside of casing 2.
The bearing column 3 is positioned in the shell 2, two oppositely arranged connecting rods 32 are fixed on two sides of the screw block 31, the ends of the connecting rods 32 are fixedly connected with the inner wall of the bearing column 3, and the number of the shooting lenses 34 corresponds to that of each row of shooting holes 422 one by one.
The article carrying groove 412 is located inside the first connecting groove 411, the first connecting groove 411 is attached to the side wall of the fixed plate 42, the second connecting groove 413 is attached to the side wall of the side plate 421, the first fixed groove 414 is formed in the bottom wall of the second connecting groove 413, the limiting rod 4212 is fixed to the lower surface of the side plate 421, the limiting rod 4212 is matched with the first fixed groove 414, the rubber gasket 4231 is fixed to the bottom end of the fastening plate 423, and one end of the fixing block 415, which is close to the second connecting groove 413, is in a spherical shape.
The operation steps and principle of the optical device for gene sequencing are as follows:
step one: placing the gene chip to be photographed in the carrying groove 412, covering the fixing plate 42 on the carrying plate 4, enabling the first connecting groove 411 to be attached to the side wall of the fixing plate 42, enabling the second connecting groove 413 to be attached to the side wall of the side plate 421, enabling the fixing block 415 to be attached to the second fixing groove 4211, enabling the limiting rod 4212 to be attached to the first fixing groove 414, enabling the fixing plate 42 to be installed with the carrying bottom plate 41, enabling the rubber gasket 4231 to be attached to the gene chip, and enabling the gene chip to be fixed in the carrying groove 412;
step two: starting the first motor 15, wherein the first motor 15 drives the lower rotating shaft 14 to rotate, the lower rotating shaft 14 drives the lower driving roller 141 and the lower driving gear 143 to rotate, the lower driving roller 141 drives the lower driving belt 142 to move, the lower driving gear 143 drives the upper driving gear 133 to rotate, the upper driving gear 133 drives the upper rotating shaft 13 to rotate, the upper rotating shaft 13 drives the upper driving roller 131 to rotate, and the upper driving roller 131 drives the upper driving belt 132 to move;
step three: the carrying plate 4 is matched with the conveying groove 12 in a plugging manner, so that the upper transmission belt 132 is attached to the upper surface of the carrying bottom plate 41, the lower transmission belt 142 is attached to the lower surface of the carrying bottom plate 41, and the carrying plate 4 moves towards the inside of the conveying groove 12;
step four: when the carrying groove 412 moves to the inside of the photographing groove 11 while the carrying groove 412 is located right under the photographing head, continuous photographing is completed, and the carrying plate 4 continues to move until all the gene chips complete continuous photographing.
Through carrier bottom plate 41 and fixed plate 42 cooperation use, it prevents to carry thing board 4 when conveyer trough 12 internal motion to fix the gene chip in carrying thing groove 412, lead to the gene chip to take place the skew and then influence the operation of shooing, the use of carrying thing board 4 makes, at the equipment during operation, the operator can use new carrying thing board 4 to load the gene chip, and then reduce the preparation time of work of shooing, the efficiency of work of shooing has been promoted, casing 2 makes the shooting of gene chip go on under sealed environment, prevent that external factor from interfering to cause the result of shooing to receive the influence, auxiliary light source 35 adjusts the light source of shooting environment, bear the cooperation of post 3 and screw rod 22 and make the focus of taking the photograph 34 can be adjusted, and then guaranteed the image definition of shooing.
The foregoing is merely illustrative and explanatory of the principles of the invention, as various modifications and additions may be made to the specific embodiments described, or similar thereto, by those skilled in the art, without departing from the principles of the invention or beyond the scope of the appended claims.

Claims (4)

1. An optical device for gene sequencing, characterized in that: including base (1), the upper surface center department of base (1) opens has shooting groove (11), the below of shooting groove (11) is equipped with conveyer trough (12), the inside of conveyer trough (12) is equipped with carries thing board (4), the inside upper end of base (1) is equipped with two upper rotating shafts (13) of opposition setting, upper rotating shaft (13) are connected with base (1) rotation, upper driving roller (131) are fixed with at the both ends of upper rotating shaft (13), install upper driving belt (132) between upper driving roller (131) of two opposition setting, one end of one of them upper rotating shaft (13) is fixed with upper driving gear (133), the inside lower extreme of base (1) is equipped with lower pivot (14) of two opposition setting, lower pivot (14) are connected with base (1) rotation, install lower driving roller (141) between the lower roller (141) of two opposition setting, one end of one of them lower pivot (14) is fixed with lower driving gear (133), lower driving gear (143) meshes with upper driving gear (motor) motor, one side of base (1) is fixed with lower driving roller (15) of one side (15), the fixed surface of first fixed with base (2) is connected with upper housing (15), the center of the outer top end of the shell (2) is fixedly provided with a second motor (21), the output end of the second motor (21) is fixedly provided with a screw rod (22), the screw rod (22) penetrates through the top wall of the shell (2), the screw rod (22) is rotationally connected with the top wall of the shell (2), the inner wall of the shell (2) is provided with two oppositely arranged sliding grooves (24), the screw rod (22) is sleeved with a bearing column (3), the inside of the bearing column (3) is provided with a screw block (31), the screw block (31) is in screw connection with the screw rod (22), the bottom end of the bearing column (3) is fixedly provided with a bearing table (33), the lower surface of the bearing table (33) is fixedly provided with a plurality of shooting lenses (34), two opposite auxiliary light sources (35) are arranged on two sides of the shooting lenses (34), the auxiliary light sources (35) are fixedly connected with the bearing table (33), the side wall of the bearing column (3) is fixedly provided with two oppositely arranged limiting slide bars (36), and the limiting slide bars (36) are matched with the sliding grooves (24).
The object carrying plate (4) comprises an object carrying bottom plate (41), a first connecting groove (411) is formed in the upper surface of the object carrying bottom plate (41), two second connecting grooves (413) which are oppositely arranged are formed in the top end of the side wall of the first connecting groove (411), a fixed block (415) is arranged on the side wall of the second connecting groove (413), the fixed block (415) is slidably connected with the side wall of the second connecting groove (413), a telescopic rod (416) is fixed at one end of the fixed block (415) far away from the second connecting groove (413), the telescopic rod (416) is fixedly connected with the inner wall of the object carrying bottom plate (41), springs (417) are sleeved on the telescopic rod (416), two ends of each spring are fixedly connected with one end of the fixed block (415) far away from the second connecting groove (413) and the inner wall of the object carrying bottom plate (41), a plurality of rows of object carrying grooves (412) which are uniformly distributed are formed in the upper surface of the object carrying bottom plate (41), side plates (42) are fixedly arranged on two sides of the fixed plates (421), a plurality of the side plates (422) are fixedly connected with the side walls (421) on the side walls of the side plates (421), the side walls of the side plates (421) are fixedly connected with the second connecting grooves (422) which are correspondingly arranged in a mode, a plurality of one-to-one shooting holes (422) are correspondingly arranged on the second fixed grooves (422) and are fixedly arranged on the side plates (422), two opposite fastening plates (423) are fixed below the shooting hole (422), and the side wall of the fastening plate (423) far away from the shooting hole (422) is attached to the side wall of the carrying groove (412);
the operation steps of the optical device are as follows:
step one: placing a gene chip to be photographed in a carrying groove (412), covering a fixing plate (42) on a carrying plate (4) to enable a first connecting groove (411) to be attached to the side wall of the fixing plate (42), enabling a second connecting groove (413) to be attached to the side wall of a side plate (421), enabling a fixing block (415) to be attached to a second fixing groove (4211) at the same time, enabling a limiting rod (4212) to be attached to a first fixing groove (414), enabling the fixing plate (42) to be installed together with a carrying bottom plate (41), enabling a rubber gasket (4231) to be attached to the gene chip, and enabling the gene chip to be fixed inside the carrying groove (412);
step two: starting a first motor (15), wherein the first motor (15) drives a lower rotating shaft (14) to rotate, the lower rotating shaft (14) drives a lower driving roller (141) and a lower driving gear (143) to rotate, the lower driving roller (141) drives a lower driving belt (142) to move, the lower driving gear (143) drives an upper driving gear (133) to rotate, the upper driving gear (133) drives an upper rotating shaft (13) to rotate, the upper rotating shaft (13) drives an upper driving roller (131) to rotate, and the upper driving roller (131) drives an upper driving belt (132) to move;
step three: the carrying plate (4) is matched with the conveying groove (12) in a plugging manner, so that the upper transmission belt (132) is attached to the upper surface of the carrying bottom plate (41), the lower transmission belt (142) is attached to the lower surface of the carrying bottom plate (41), and the carrying plate (4) moves towards the inside of the conveying groove (12);
step four: when the object carrying groove (412) moves to the inside of the shooting groove (11), and meanwhile, the object carrying groove (412) is positioned under the shooting machine head, continuous shooting is completed, and the object carrying plate (4) continues to move until all the gene chips complete continuous shooting;
the conveying groove (12) is communicated with the inside of the shooting groove (11), the conveying groove (12) penetrates through the base (1), the upper rotating shaft (13) is located above the conveying groove (12), the conveying groove (12) is located on two sides of the shooting groove (11), the lower rotating shaft (14) is located below the conveying groove (12), and the upper rotating shaft (13) and the lower rotating shaft (14) located on the same side are located on the same horizontal vertical line;
the lower surface of last drive belt (132) be located the inside of conveyer trough (12), go up drive belt (132) and be located the both sides of shooting groove (11), the upper surface of lower drive belt (142) is located the inside of conveyer trough (12), lower drive belt (142) are located the both sides of shooting groove (11), go up drive gear (133) and lower drive gear (143) and be located the inside of base (1).
2. The optical device for gene sequencing according to claim 1, wherein: the camera lens (34) is electrically connected with the display screen, two limiting blocks (23) which are oppositely arranged are fixed on two sides of the bottom end of the screw rod (22), and the limiting blocks (23) are located in the shell (2).
3. The optical device for gene sequencing according to claim 1, wherein: the bearing column (3) is located inside the shell (2), two oppositely arranged connecting rods (32) are fixed on two sides of the screw block (31), the ends of the connecting rods (32) are fixedly connected with the inner wall of the bearing column (3), and the number of the shooting lenses (34) corresponds to that of each row of shooting holes (422) one by one.
4. The optical device for gene sequencing according to claim 1, wherein: the utility model discloses a carry thing groove (412) be located the inside in first spread groove (411), first spread groove (411) is laminated mutually with the lateral wall of fixed plate (42), second spread groove (413) is laminated mutually with the lateral wall of curb plate (421), the diapire in second spread groove (413) is opened there is first fixed slot (414), the lower surface of curb plate (421) is fixed with gag lever post (4212), gag lever post (4212) cooperate with first fixed slot (414), the bottom mounting of fastening plate (423) has rubber gasket (4231), the one end that fixed block (415) is close to second spread groove (413) is spherical.
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