CN111543423A - Intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device - Google Patents
Intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device Download PDFInfo
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- CN111543423A CN111543423A CN202010267138.3A CN202010267138A CN111543423A CN 111543423 A CN111543423 A CN 111543423A CN 202010267138 A CN202010267138 A CN 202010267138A CN 111543423 A CN111543423 A CN 111543423A
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- module
- box body
- control panel
- transfer device
- portable multifunctional
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
Abstract
The invention provides an intelligent portable multifunctional cell or tissue low-temperature storage and transfer device, which adopts a miniature evaporation compression type refrigerating system, can meet the requirements of different transferred articles on transfer temperature, simultaneously has the refrigeration of a cold storage agent, has simple and reasonable structural layout, is light in weight and is beneficial to portability; during storage and transportation, the refrigerating system provides stable cold energy to the interior, the heat preservation layer blocks the loss of the cold energy, the interior is ensured to be in a low-temperature state required by specimen transportation, and when the specimen needs to be transported in an environment where the refrigerating system cannot operate, cold energy can be provided by using a cold storage agent; but intelligent terminal real-time feedback and record position among the transportation, the humiture change, open the closure, whether receive important information such as striking, and at low-power, super warm area, receive important striking constantly and give the police dispatch newspaper, so that the staff in time handles, and simultaneously, be favorable to promoting the standardization of transportation, the standardization, guarantee the traceability of transporting, in addition, realize being connected of device and cell-phone APP through bluetooth receiver, broken and to have followed the limitation that shows/button module input control command.
Description
Technical Field
The invention relates to the technical field of cell transfer, in particular to an intelligent portable multifunctional cell or tissue low-temperature storage and transfer device.
Background
With the rapid development of biomedical technology/foundation and clinical medicine, the development of life science research is greatly promoted, and the method makes outstanding contributions to the understanding of self/attacking diseases/prolonging life/improving life quality of all mankind. However, all life science researches relate to preservation and transportation of cell tissues and specimens, and safe/convenient transportation of the cell tissues and the specimens is a crucial link for all life science researches. Little to the transfer of cryopreserved cells, and much to the transfer of tissue specimens and organs without involving the influence of the cryopreservation and transfer devices, the different items being transferred having different requirements for transfer temperature, and even less than all of the attempts to lose leaf cells. However, the specialized transfer devices currently available are almost blank.
A plurality of uncertain factors exist in the transfer process of a biological sample, irreversible damage can be caused to the biological sample due to temperature fluctuation, external force impact and the like in the transfer process, and a complete monitoring system for real-time recording and alarming of transfer indexes (position, temperature and humidity fluctuation, stress conditions and the like) is lacking at present. In recent years, the technical layer and the application layer of the internet of things are updated in a dispute, and in the field of biomedicine, for the transportation of cell tissues and organs, the application of the technology of the internet of things can record and upload transportation indexes to the cloud in real time, thereby being beneficial to promoting the standardization and normalization of the transportation process and ensuring the traceability/traceability of the transportation.
At present, a commonly used cell tissue low-temperature freezing device needs to adopt a liquid nitrogen or an ultra-low temperature refrigerator as a cold source, and the device is complex and large in structure and inconvenient to transport. The development of a micro refrigeration system enables the portability of the cell tissue low-temperature cryopreservation device.
The application of the refrigeration technology is limited by the condition of the external environment, for example, during shipping, the active refrigeration can not provide cold for transported articles and maintain the low temperature state without the support of a storage battery. The problem that cold cannot be supplied can be solved in a short time by using the cold storage agent for refrigeration, and the application flexibility of the device is improved.
Disclosure of Invention
The invention aims to provide an intelligent portable multifunctional cell or tissue low-temperature storage and transfer device which is strong in intelligence, wide in application range and good in storage effect.
In order to achieve the purpose, the invention provides an intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device, which comprises a device body and an intelligent terminal;
the device body comprises a box cover and a box body, the box body comprises an outer box body and an inner box body, the inner box body is arranged in the outer box body, a heat insulation material is preset between the outer box body and the inner box body, an evaporation module, a condensation module and a storage battery are preset between the bottom surface of the inner box body and the bottom surface of the outer box body, and the storage battery is electrically connected with the evaporation module and the condensation module; the evaporation module and the condensation module are isolated by arranging a first heat insulation layer; a coolant placing layer is arranged on the side surface of the inner box body;
the box cover and the box body are isolated by a second heat insulation layer; the intelligent terminal, the lithium battery and the storage hard disk are preset in the box cover; the storage hard disk is in signal connection with the intelligent terminal, and the lithium battery is electrically connected with the intelligent terminal.
Preferably, the intelligent terminal comprises a control panel, a communication module, a hall sensor, a satellite positioning module, an acceleration sensor, a temperature and humidity sensor and a display/key module; each module of the intelligent terminal is electrically connected with the lithium battery;
the control panel comprises an MCU, an information acquisition element and an alarm element.
Preferably, the communication module, the hall sensor, the satellite positioning module, the acceleration sensor, the temperature and humidity sensor, the display/key module, the evaporation module and the condensation module are in signal connection with the MCU of the control panel.
Preferably, the communication module is integrated with a bluetooth receiver and a radio frequency identification module RFI.
Preferably, the left side and the right side of the outer box body close to the bottom are both preset with vent holes, and dust screens are preset on the vent holes.
Preferably, an alternating current/direct current charging port is arranged on the storage battery, and the storage battery is electrically connected with the overvoltage protector and the electric quantity detector; and the electric quantity detector is in signal connection with the MCU of the control panel.
Preferably, a lighting device is preset on one surface of the box cover facing the box body, and the lighting device is electrically connected with the lithium battery; the lighting device is in signal connection with the control panel and is a photosensitive lamp source.
Preferably, a comparison unit is preset in the MCU of the control panel, and when the temperature, the inertia force and the battery power are not within a set range, the MCU can control the alarm element to send out a corresponding alarm.
Preferably, the control panel is in signal connection with an external mobile device through the communication module, the MCU of the control panel transmits information data to other remote terminals through the communication module, and displays the information data on the display/key module, and the RFID integrated with the communication module reads basic information of transported articles; the tracing of the transfer process is perfected; the Bluetooth receiver integrated with the communication module can realize the connection between the control panel and the mobile phone APP.
Preferably, a floor mat is preset at the bottom of the device body;
threaded holes are preset in the side face of the device body, and a lifting beam is convenient to mount.
Compared with the prior art, the invention has the advantages that:
1. in the invention, heat insulating materials are scientifically arranged between the inner box body and the outer box body, the box cover and the box bodies are respectively provided with the heat insulating layer, meanwhile, the refrigerating system stably inputs cold energy to ensure that the interior is in a low-temperature state, and in addition, the refrigerating module and the condensing module are separated by the heat insulating layer, so that cold and heat separation is realized, and the cold energy loss is effectively reduced.
2. According to the invention, the miniature evaporation compression type refrigeration system is adopted, so that the requirement of different transported articles on the transport temperature can be met, and meanwhile, the refrigeration of the cold storage agent is realized, the structural layout is simple and reasonable, the weight is light, and the portability is facilitated. When needs are transported in the unable environment of operation of active refrigerating system, if shipping, also can provide cold volume with settling the coolant of putting intraformational cold-storage agent in the coolant, increased the flexibility of transporting, can adapt to the transportation of more situations.
3. According to the device, based on technologies such as Internet of things, RFID and wireless communication, through cooperation of each sensor and the communication module, the device has the functions of monitoring data information such as temperature and humidity, opening states, position location and battery power in real time, can send out corresponding alarms in emergency, meanwhile, traceability of an article transfer process is achieved, and standardization and normalization of a biological sample transfer process are promoted. In addition, device accessible bluetooth receiver forms with cell-phone APP and is connected, has richened the interactive mode between staff and the equipment.
Drawings
Fig. 1 is a schematic diagram of the structure of an intelligent portable multifunctional cell or tissue cryopreservation and transfer device.
Fig. 2 is a front view of an intelligent portable multifunctional cell or tissue cryopreservation and transfer device.
Fig. 3 is a left side view of an intelligent portable multi-functional cell or tissue cryopreservation and transfer device.
Fig. 4 is a hardware schematic block diagram of an intelligent terminal in an intelligent portable multifunctional cell or tissue cryopreservation and transfer device.
Fig. 5 is a control flow chart of an intelligent portable multifunctional cell or tissue cryopreservation and transfer device.
Fig. 6 is a refrigeration schematic diagram of an intelligent portable multifunctional cell or tissue cryopreservation and transfer device.
In the figure: 1. a condensing module; 2. a floor pad; 3. a storage battery; 4. an electric quantity detector; 5. an overvoltage protector; 6. a first insulating layer; 7. an AC/DC charging port; 8. an evaporation module; 9. a dust screen; 10. a vent hole; 11. a coolant-holding layer; 12. a threaded hole; 13. storing the hard disk; 14. a thermal insulation material; 15. a second thermal insulation layer; 16. a USB interface; 17. a display/key module; 18. a control panel; 19. a communication module; 20. a Hall sensor; 21. a satellite positioning module; 22. an acceleration sensor; 23. a temperature and humidity sensor; 24. a lithium battery; 25. an illumination device; 26. an outer case; 27. an inner box body; 28. a vent hole.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be further described below.
As shown in fig. 1, fig. 2 and fig. 3, the present invention provides an intelligent portable multifunctional cell or tissue cryopreservation and transfer device, which comprises a device body and an intelligent terminal;
the device body comprises a box cover and a box body, the box body comprises an outer box body 26 and an inner box body 27, the inner box body 27 is arranged in the outer box body 26, a heat insulation material 14 is arranged between the outer box body 26 and the inner box body 27 in advance, an evaporation module 8, a condensation module 1 and a storage battery 3 are arranged between the bottom surface of the inner box body 27 and the bottom surface of the outer box body 26 in advance, and the storage battery 3 is electrically connected with the evaporation module 8 and the condensation module 1; the evaporation module 8 and the condensation module 1 are isolated by arranging a first heat-insulating layer 6; the side surface of the inner box body 27 is provided with a coolant placing layer 11;
the box cover and the box body are isolated by a second heat insulation layer 15; the intelligent terminal, the lithium battery 24 and the storage hard disk 13 are preset in the box cover; the storage hard disk 13 is provided with a USB interface 16, the storage hard disk 13 is in signal connection with the intelligent terminal, and the lithium battery 24 is electrically connected with the intelligent terminal.
In this embodiment, as shown in fig. 4, the intelligent terminal includes a control panel 18, a communication module 19, a hall sensor 20, a satellite positioning module 21, an acceleration sensor 22, a temperature and humidity sensor 23, and a display/key module 17; each module of the intelligent terminal is electrically connected with the lithium battery 24;
the control panel 18 comprises an MCU, an information acquisition element and an alarm element, and the communication module 19, the Hall sensor 20, the satellite positioning module 21, the acceleration sensor 22, the temperature and humidity sensor 23, the display/key module 17, the evaporation module 8 and the condensation module 1 are all in signal connection with the MCU of the control panel 18. The temperature and humidity sensor 23 continuously transmits temperature and humidity data to an information acquisition element of the control panel 18 in real time, the satellite positioning module 21 continuously transmits position change of a transfer process to the information acquisition element in real time, the Hall sensor 20 transmits opening and closing change of the box cover to the information acquisition element, the electric quantity detector 4 continuously transmits residual electric quantity of the storage battery 3 to the information acquisition element in real time, the acceleration sensor 22 continuously transmits inertial force applied to the box body to the information acquisition element in real time, and the information acquisition element of the control panel 18 transmits acquired information to the MCU of the control panel 18.
In the present embodiment, the communication module 19 is integrated with a bluetooth receiver and a radio frequency identification module RFID.
In this embodiment, ventilation holes 2810 are provided in both left and right sides of the outer box 26 near the bottom, and dust screens 9 are provided in the ventilation holes 2810.
In the embodiment, an alternating current/direct current charging port 7 is arranged on the storage battery 3, and the storage battery 3 is electrically connected with the overvoltage protector 5 and the electric quantity detector 4; the electric quantity detector 4 is in signal connection with the MCU of the control panel 18.
In the embodiment, the lighting device 25 is preset on the surface of the box cover facing the box body, and the lighting device 25 is electrically connected with the lithium battery 24; the lighting device 25 is in signal connection with the control panel 18, and the lighting device 25 is a photosensitive lamp source.
In this embodiment, the comparing unit is preset in the MCU of the control panel 18, and when the temperature, the inertia force, and the battery power are not within the set range, the MCU will control the alarm device to issue a corresponding alarm.
In this embodiment, as shown in fig. 5, the control panel 18 is in signal connection with an external mobile device through the communication module 19, the MCU of the control panel 18 transmits information data to other remote terminals through the communication module 19, and displays the information data on the display/key module 17, and the RFID identification reader/writer integrated through the communication module 19 is written on the electronic tag card corresponding to each transported article, so as to improve the tracing of the transportation process; the integrated bluetooth receiver of communication module 19 can realize being connected of control panel 18 and cell-phone APP, and the cell-phone APP can look over the transportation data, and cell-phone APP can realize transmitting control command to control panel 18 simultaneously, like rise or fall the temperature, relieve commands such as alarm, has broken the limitation that can only follow display/button module 17 input control command.
In this embodiment, the floor mat 2 is preset at the bottom of the device body; threaded holes 12 are preset in the side face of the device body, and a lifting beam is convenient to mount.
As shown in fig. 4, 5 and 6, the working principle of the invention is that the invention utilizes the principle of evaporation and heat absorption, the evaporation module 8 sends cold energy into the box body, and the condensation module 1 transfers the heat energy to the environment, and meanwhile, the evaporation module 8 and the condensation module 1 are separated by a heat insulation layer, thereby achieving the cold-heat separation and improving the energy utilization efficiency; before the articles to be transported are put in, a refrigerating system is started to pre-cool at a corresponding temperature, so that the articles are always in a low-temperature state in the transporting process. When the cold storage agent needs to be transported in an environment where an active refrigeration system cannot operate, such as shipping, passive refrigeration is adopted, the cold storage agent which is frozen in advance is placed in the cold storage agent placing layer 11 in the box, and melting heat absorption and phase change heat absorption of the cold storage agent are utilized.
The intelligent terminal is started at the initial stage of the transportation, and is independently powered by the lithium battery 24 without the limitation of special conditions such as shipping and the like; the temperature and humidity sensor 23 continuously transmits temperature and humidity data to an information acquisition element of the control panel 18 in real time, the satellite positioning module 21 continuously transmits position change of a transfer process to the information acquisition element in real time, the Hall sensor 20 transmits opening and closing change of the box cover to the information acquisition element, the electric quantity detector 4 continuously transmits residual electric quantity of the storage battery 3 to the information acquisition element in real time, the acceleration sensor 22 continuously transmits inertia force borne by the box body to the information acquisition element in real time, the information acquisition element transmits acquired information to the control unit MCU of the control panel 18, on one hand, the MCU transmits the information data to other remote terminals through the communication module 19 and displays the data on the display/key module 17, when the data information is transmitted to other terminals, the data is automatically backed up and stored to the storage hard disk 13, and data loss caused by no communication signal and other reasons such as transmission to other terminals is prevented, in addition, the RFID identification module integrated by the communication module 19 reads basic information of the transported item, such as information of a name destination and the like; specifically, the RFID mainly comprises a reader and an electronic tag, wherein the electronic tag is attached to a container (generally a test tube) for transporting goods, and some basic information such as name, destination of the origin of transportation, dosage and the like can be written in the electronic tag before transportation, so that when the transported goods attached with the electronic tag are placed in a box and an intelligent terminal supplies power, the reader can spontaneously read the information on the electronic tag, in the transportation process, the environment information of changes such as temperature and humidity is needed, the transported goods also need to be known, and the intelligent completion of the transportation process can be realized through the RFID.
On the other hand, the MCU is internally provided with a comparison unit, when the temperature, the inertia force and the battery power are not in the set range, namely when the temperature exceeds the standard, the battery is violently impacted and the power is insufficient, the MCU can control the alarm element to send out corresponding alarm so that the working personnel can respond in time.
Realize being connected of control panel 18 and cell-phone APP through the integrated bluetooth receiver of communication module 19, the cell-phone APP can look over the transportation data, and cell-phone APP can be to control panel 18 input control command simultaneously, like rise or fall the temperature, relieve alarm etc. and broken the limitation that can only follow demonstration/button module 17 input control command, richen the variety of interaction pattern.
The above description is only a preferred embodiment of the present invention, and does not limit the present invention in any way. It will be understood by those skilled in the art that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (10)
1. An intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device is characterized by comprising a device body and an intelligent terminal;
the device body comprises a box cover and a box body, the box body comprises an outer box body and an inner box body, the inner box body is arranged in the outer box body, a heat insulation material is preset between the outer box body and the inner box body, an evaporation module, a condensation module and a storage battery are preset between the bottom surface of the inner box body and the bottom surface of the outer box body, and the storage battery is electrically connected with the evaporation module and the condensation module; the evaporation module and the condensation module are isolated by arranging a first heat insulation layer; a coolant placing layer is arranged on the side surface of the inner box body;
the box cover and the box body are isolated by a second heat insulation layer; the intelligent terminal, the lithium battery and the storage hard disk are preset in the box cover; the storage hard disk is in signal connection with the intelligent terminal, and the lithium battery is electrically connected with the intelligent terminal.
2. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 1, wherein the intelligent terminal comprises a control panel, a communication module, a hall sensor, a satellite positioning module, an acceleration sensor, a temperature and humidity sensor and a display/key module; each module of the intelligent terminal is electrically connected with the lithium battery;
the control panel comprises an MCU, an information acquisition element and an alarm element.
3. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 2, wherein the communication module, the hall sensor, the satellite positioning module, the acceleration sensor, the temperature and humidity sensor, the display/key module, the evaporation module and the condensation module are in signal connection with the MCU of the control panel.
4. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device of claim 2 wherein the communication module integrates a bluetooth receiver and a radio frequency identification module RFID.
5. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 1, wherein ventilation holes are preset at the left and right sides of the outer box near the bottom, and dust screens are preset on the ventilation holes.
6. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 2, wherein an ac/dc charging port is arranged on the storage battery, and the storage battery is electrically connected with the overvoltage protector and the electricity detector; and the electric quantity detector is in signal connection with the MCU of the control panel.
7. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 2, wherein a lighting device is preset on one side of the box cover facing the box body, and the lighting device is electrically connected with the lithium battery; the lighting device is in signal connection with the control panel and is a photosensitive lamp source.
8. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 2, wherein a comparison unit is preset in the MCU of the control panel, and when the temperature, the inertia force and the battery power are not in a set range, the MCU controls the alarm element to give out a corresponding alarm.
9. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 2, wherein the control panel is in signal connection with an external mobile device through the communication module, the MCU of the control panel transmits information data to other remote terminals through the communication module and displays the information data on the display/key module, and in addition, the RFID module integrated with the communication module reads basic information of transferred articles, so as to complete the tracing of the transfer process; the Bluetooth receiver integrated with the communication module can realize the connection between the control panel and the mobile phone APP.
10. The intelligent portable multifunctional cell or tissue cryopreservation and transfer device as claimed in claim 1, wherein a floor mat is pre-installed at the bottom of the device body;
threaded holes are preset in the side face of the device body, and a lifting beam is convenient to mount.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010267138.3A CN111543423A (en) | 2020-04-08 | 2020-04-08 | Intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010267138.3A CN111543423A (en) | 2020-04-08 | 2020-04-08 | Intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device |
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| CN111543423A true CN111543423A (en) | 2020-08-18 |
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| CN202010267138.3A Pending CN111543423A (en) | 2020-04-08 | 2020-04-08 | Intelligent portable multifunctional cell or tissue low-temperature preservation and transfer device |
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Application publication date: 20200818 |