CN111529225A - Ambulance with function of immediately detecting new coronavirus in air - Google Patents
Ambulance with function of immediately detecting new coronavirus in air Download PDFInfo
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- CN111529225A CN111529225A CN202010534400.6A CN202010534400A CN111529225A CN 111529225 A CN111529225 A CN 111529225A CN 202010534400 A CN202010534400 A CN 202010534400A CN 111529225 A CN111529225 A CN 111529225A
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- ambulance
- new coronavirus
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- air
- control device
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- 241000711573 Coronaviridae Species 0.000 title claims abstract description 46
- 238000001514 detection method Methods 0.000 claims abstract description 38
- 238000004891 communication Methods 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 5
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 4
- 239000010931 gold Substances 0.000 description 4
- 229910052737 gold Inorganic materials 0.000 description 4
- 241000700605 Viruses Species 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 241001678559 COVID-19 virus Species 0.000 description 2
- 102000053602 DNA Human genes 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 2
- 201000003176 Severe Acute Respiratory Syndrome Diseases 0.000 description 2
- 238000003759 clinical diagnosis Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000002086 nanomaterial Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000003757 reverse transcription PCR Methods 0.000 description 2
- 229920002477 rna polymer Polymers 0.000 description 2
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 2
- 208000001528 Coronaviridae Infections Diseases 0.000 description 1
- 108010069941 DNA receptor Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001588 bifunctional effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000007901 in situ hybridization Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000003771 laboratory diagnosis Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000007899 nucleic acid hybridization Methods 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 238000007430 reference method Methods 0.000 description 1
- 238000011896 sensitive detection Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
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- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G3/00—Ambulance aspects of vehicles; Vehicles with special provisions for transporting patients or disabled persons, or their personal conveyances, e.g. for facilitating access of, or for loading, wheelchairs
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Abstract
An ambulance with the function of immediately detecting new coronavirus in the air comprises the ambulance and a detection device, wherein the detection device is arranged on the ambulance and can detect the new coronavirus in the air inside the ambulance; the detection device comprises a new coronavirus detection sensor, a power supply, an alarm device and a control device, wherein the new coronavirus detection sensor is electrically connected with the control device, and the power supply is respectively electrically connected with the new coronavirus detection sensor, the alarm device and the control device. The invention has simple structure and convenient use, can accurately and timely detect whether the interior of the ambulance contains the novel coronavirus, can generate an alarm, directly protects the life safety of medical personnel, common patients and other personnel, and has great significance.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to an ambulance with a function of instantly detecting new coronavirus in the air.
Background
The new type of coronavirus disease (COVID-19) is spreading worldwide and poses a threat to public health in over 200 countries. Reliable laboratory diagnosis of disease has always been one of the top priorities to facilitate public health interventions. The conventionally used reverse transcription polymerase chain reaction (RT-PCR) is currently the reference method for COVID-19 diagnosis. However, it also reports some false positive or negative cases, especially in the early stages of new virus outbreaks. In this work, a bifunctional plasmonic biosensor combining Plasmonic Photothermal (PPT) effect and Localized Surface Plasmon Resonance (LSPR) sensing transduction provides an alternative and promising solution for clinical diagnosis of COVID-19. Complementary functionalization of two-dimensional gold nano-islands (AuNIs) with DNA receptors enables sensitive detection of SARS-CoV-2 sequences by nucleic acid hybridization. For better inductive performance, thermal plasma heat is generated on the same AuNIs chip when illuminated at the plasma resonance frequency. The positioned PPT heat can improve the in-situ hybridization temperature, and is convenient for accurately identifying two similar gene sequences. Our dual-function LSPR biosensor has high sensitivity to the selected SARS-CoV-2 sequence, with detection limit as low as 0.22 pM, allowing accurate detection of specific targets in a multigene mixture. The present study has conducted an intensive study on thermal plasma enhancement and its application in nucleic acid detection and viral disease diagnosis.
Disclosure of Invention
The present invention is directed to solving the problems and deficiencies of the prior art by providing an ambulance with the capability of detecting new coronavirus in the air in real time.
An ambulance with the function of immediately detecting new coronavirus in the air comprises the ambulance and a detection device, wherein the detection device is arranged on the ambulance and can detect the new coronavirus in the air inside the ambulance;
the detection device comprises a new coronavirus detection sensor, a power supply, an alarm device and a control device, wherein the new coronavirus detection sensor is electrically connected with the control device, and the power supply is respectively electrically connected with the new coronavirus detection sensor, the alarm device and the control device.
The invention has the beneficial effects that:
the invention has simple structure and convenient use, can accurately and timely detect whether the interior of the ambulance contains the novel coronavirus, can generate an alarm, directly protects the life safety of medical personnel, common patients and other personnel, and has great significance.
Drawings
Fig. 1 is a perspective view of the present invention.
Fig. 2 is a schematic view of the detection device disposed inside the ambulance.
FIG. 3 is a flow chart of the use of the detecting device of the present invention.
Fig. 4 is a schematic diagram of an embodiment in which the control device is a PLC module.
Detailed Description
Referring to fig. 1 to 4, an ambulance with a function of instantly detecting new coronavirus in the air comprises an ambulance 1 and a detection device 2, wherein the detection device 2 is disposed on the ambulance 1 and can detect new coronavirus in the air inside the ambulance;
the detection device 2 comprises a new coronavirus detection sensor 20, a power supply 21, an alarm device 22 and a control device 23, wherein the new coronavirus detection sensor 20 is electrically connected with the control device 23, and the power supply 21 is respectively electrically connected with the new coronavirus detection sensor 20, the alarm device 22 and the control device 23.
Furthermore, the control device 23 includes a single chip microcomputer and an a/D switch, one end of the a/D switch is electrically connected to the new coronavirus detection sensor 20, the other end of the a/D switch is electrically connected to the single chip microcomputer, and the single chip microcomputer is electrically connected to the alarm device 22.
More specifically, the control device 23 includes a PLC module 24 and an analog module 25, one end of the analog module 25 is electrically connected to the new coronavirus detection sensor 20, the other end of the analog module 25 is electrically connected to the PLC module 24, and the PLC module 24 is electrically connected to the alarm device 22.
Furthermore, the PLC intelligent control system further comprises a wireless communication module 26 and an upper computer 27, wherein the wireless communication module 26 is electrically connected with the PLC module 24, and the upper computer 27 is wirelessly connected with the wireless communication module 26.
More specifically, the power supply 21 is an automotive power supply.
More specifically, the alarm device 22 is a buzzer or a flashing alarm light.
The working principle and the using process of the invention are as follows:
referring to fig. 1 to 4, when a new coronavirus inside the ambulance 1 is detected by the new coronavirus detection sensor 20, an electric signal is generated and transmitted to an A/D conversion switch or an analog quantity module 25, the A/D conversion switch or the analog quantity module 25 is used for converting a digital signal into an analog quantity signal which can be identified by a singlechip or a PLC module 24, the singlechip or the PLC module 24 outputs the signal to an alarm device 22, the alarm device 22 generates an alarm to remind medical personnel, if the control device 23 is the PLC module 24, the PLC module will send a signal to the wireless communication module 26, and the wireless communication module 26 will send the signal to the inside of the mobile phone of the medical staff or ambulance driver, and the alarm device 22 can be a visual alarm flashing light or an audible buzzer.
The applicant provides the following information as support to confirm that the new coronavirus detection sensor is prior art.
A research group of Switzerland announces 21 days that the research group develops a biosensor capable of sensitively and reliably detecting the new coronavirus in the air, which not only can be used as a substitute method for clinical diagnosis of new coronavirus infection, but also can be used for detecting whether the new coronavirus exists in the air of crowded places such as railway stations, hospitals and the like.
The swiss federal materials science and technology laboratory published on day 21 states that this new biosensor was developed by the agency in cooperation with the university of federal and technology in zurich, university hospital, etc., based on gold nanostructures called "gold nano islands" prepared on a glass substrate, and researchers "grafted" a DNA (deoxyribonucleic acid) receptor artificially synthesized to match the RNA (ribonucleic acid) sequence of a new coronavirus onto the gold nanostructures to enable it to recognize the new coronavirus.
The novel sensor detection process of viruses is described to utilize two different effects of Localized Surface Plasmon Resonance (LSPR) and plasmon photo-thermal (PPT) to increase the reliability of detection. Experiments show that the sensor can accurately identify two viruses with similar gene sequences, namely a new coronavirus and a Severe Acute Respiratory Syndrome (SARS) coronavirus, and obtain a detection result within a few minutes.
The new coronavirus detection sensor is described in detail in ACSNano journal, 4/2020, and 5268-5277 of 14 th.
Claims (6)
1. An ambulance with the function of instantly detecting new coronavirus in the air is characterized in that: the device comprises an ambulance (1) and a detection device (2), wherein the detection device (2) is arranged on the ambulance (1) and can detect new coronavirus in the air inside the ambulance;
the detection device (2) comprises a new coronavirus detection sensor (20), a power supply (21), an alarm device (22) and a control device (23), the new coronavirus detection sensor (20) is electrically connected with the control device (23), and the power supply (21) is respectively electrically connected with the new coronavirus detection sensor (20), the alarm device (22) and the control device (23).
2. The ambulance with the function of instantly detecting new coronavirus in the air as claimed in claim 1, wherein: the control device (23) comprises a single chip microcomputer and an A/D conversion switch, one end of the A/D conversion switch is electrically connected with the new coronavirus detection sensor (20), the other end of the A/D conversion switch is electrically connected with the single chip microcomputer, and the single chip microcomputer is electrically connected with the alarm device (22).
3. The ambulance with the function of instantly detecting new coronavirus in the air as claimed in claim 1, wherein: the control device (23) comprises a PLC module (24) and an analog quantity module (25), one end of the analog quantity module (25) is electrically connected with the new coronavirus detection sensor (20), the other end of the analog quantity module is electrically connected with the PLC module (24), and the PLC module (24) is electrically connected with the alarm device (22).
4. The ambulance with the function of instantly detecting new coronavirus in the air as claimed in claim 1, wherein: the control device (23) further comprises a wireless communication module (26) and an upper computer (27), the wireless communication module (26) is electrically connected with the PLC module (24), and the upper computer (27) is in wireless connection with the wireless communication module (26).
5. The ambulance with the function of instantly detecting new coronavirus in the air as claimed in claim 1, wherein: the power supply (21) is a vehicle-mounted power supply of an automobile.
6. The ambulance with the function of instantly detecting new coronavirus in the air as claimed in claim 1, wherein: the alarm device (22) is a buzzer or an alarm flashing lamp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010534400.6A CN111529225A (en) | 2020-06-12 | 2020-06-12 | Ambulance with function of immediately detecting new coronavirus in air |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010534400.6A CN111529225A (en) | 2020-06-12 | 2020-06-12 | Ambulance with function of immediately detecting new coronavirus in air |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111529225A true CN111529225A (en) | 2020-08-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010534400.6A Pending CN111529225A (en) | 2020-06-12 | 2020-06-12 | Ambulance with function of immediately detecting new coronavirus in air |
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| Country | Link |
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| CN (1) | CN111529225A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113607505A (en) * | 2021-08-24 | 2021-11-05 | 鲁东大学 | Medical science virus detection device in air |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7101420B1 (en) * | 2004-02-23 | 2006-09-05 | Adria Valley Anne Nelson Ellis | Self cleaning air filtration machine and a method for using the same |
| CN102174382A (en) * | 2011-01-18 | 2011-09-07 | 北京大学 | System and method for monitoring bioaerosol in real time |
| CN103884697A (en) * | 2014-01-17 | 2014-06-25 | 云南安防科技有限公司 | Biological agent detection alarm apparatus |
| WO2016077466A1 (en) * | 2014-11-12 | 2016-05-19 | Baylor College Of Medicine | Mobile clinics |
-
2020
- 2020-06-12 CN CN202010534400.6A patent/CN111529225A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7101420B1 (en) * | 2004-02-23 | 2006-09-05 | Adria Valley Anne Nelson Ellis | Self cleaning air filtration machine and a method for using the same |
| CN102174382A (en) * | 2011-01-18 | 2011-09-07 | 北京大学 | System and method for monitoring bioaerosol in real time |
| CN103884697A (en) * | 2014-01-17 | 2014-06-25 | 云南安防科技有限公司 | Biological agent detection alarm apparatus |
| WO2016077466A1 (en) * | 2014-11-12 | 2016-05-19 | Baylor College Of Medicine | Mobile clinics |
Non-Patent Citations (1)
| Title |
|---|
| 无: "国际频道", 《科技传播》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113607505A (en) * | 2021-08-24 | 2021-11-05 | 鲁东大学 | Medical science virus detection device in air |
| CN116577156A (en) * | 2021-08-24 | 2023-08-11 | 鲁东大学 | Virus detection device containing buffer piece |
| CN116577156B (en) * | 2021-08-24 | 2023-11-17 | 鲁东大学 | Virus detection device containing buffer piece |
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Application publication date: 20200814 |
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