CN111521802A - Special kit for screening gastric precancerous lesions - Google Patents

Special kit for screening gastric precancerous lesions Download PDF

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Publication number
CN111521802A
CN111521802A CN202010394089.XA CN202010394089A CN111521802A CN 111521802 A CN111521802 A CN 111521802A CN 202010394089 A CN202010394089 A CN 202010394089A CN 111521802 A CN111521802 A CN 111521802A
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sampling
tube
detection
reagent tube
detection box
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CN202010394089.XA
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Chinese (zh)
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李佃贵
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Individual
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57446Specifically defined cancers of stomach or intestine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a special kit for screening gastric precancerous lesions, and relates to the technical field of medical treatment. It comprises an operation table; the left side of the operating platform is provided with a sampling device, and the right side of the operating platform is provided with a detection device; the sampling device comprises a sampling bag, isolation paper and a permanent magnet; the detection device comprises a reagent tube and a detection box; a liquid dropping needle tube is arranged on the right side of the upper end of the detection box; the lower end of the dropping liquid needle tube is in butt joint communication with the sample adding position of the test paper; the right side of the upper end of the packaging box is provided with a connecting pipe; a sealing column is arranged in the connecting pipe; the lower sheet of the sealing column is fixedly connected with the upper end of the detection box; the dropping needle tube and the puncture head are inserted in the sealing column; a support ring is arranged at the lower part in the reagent tube; the interior of the reagent tube is filled with a diluent. The invention has the beneficial effects that: the sampling is convenient at the closed port, and the closed detection operation is convenient.

Description

Special kit for screening gastric precancerous lesions
Technical Field
The invention relates to the technical field of medical treatment.
Background
Cancer is present medical difficult problem, only early discovery just is favorable to treating successfully, can early discover to cooperate more convenient detection technique, to pathological change before the stomach cancer, usable saliva sample detects among the prior art, puts the application of sample department of test paper with saliva sample diluent and detects, can observe the result in the detection zone. However, the existing kit has defects and deficiencies in the sampling and detecting process, for example, in the sampling process of saliva, a patient needs to rinse his mouth first and then open his mouth to sample, because the mouth is just rinsed, the oral cavity of the patient may not have enough saliva produced, and at the same time, the mouth is opened for a long time, which is easy to cause infection of respiratory diseases and the like, especially in a period with serious viral infection, if the patient carries viruses, the patient is easy to infect others, if there is a possibility of viruses in the surrounding environment, the safety of the patient is not easy to be ensured, so a device capable of completing sampling by closing the mouth is needed, the number of times of opening the mouth and the time of opening the mouth are reduced, and meanwhile, the sampling can be rapidly and effectively performed, for example, the oral mucosa of the patient needs to be; in the existing detection kit, general test paper needs to be contacted with the external environment in use, and pollution failure is easily caused at the moment; sometimes, the sample needs to be stored, but the conventional detection and storage processes are separately processed, so that the operation is troublesome, and the mark storage is troublesome; in the detection process, matching of multiple marks is required, for example, one mark is sampled, one mark is processed, and the other mark is marked again in the detection process, so that errors are easily caused.
Disclosure of Invention
The invention aims to solve the technical problem and provides a special kit for screening gastric precancerous lesions aiming at the technical defects. The sampling is convenient at the closed port, and the closed detection operation is convenient.
The technical scheme adopted by the invention is as follows: provides a special kit for screening gastric precancerous lesions, which comprises an operation table; the left side of the operating platform is provided with a sampling device, and the right side of the operating platform is provided with a detection device; the sampling device comprises a sampling bag, isolation paper and a permanent magnet; the interior of the sampling bag is filled with adsorption cotton; a plurality of sampling holes are formed on the surface of the sampling capsule; the surface of the sampling bag is provided with a latticed sampling strip; iron chips are filled in the side wall of the sampling bag; the end part of the permanent magnet is sleeved with an isolation rubber sleeve; the detection device comprises a reagent tube and a detection box; test paper is packaged in the detection box; the upper end of the detection box is made of transparent material; a liquid dropping needle tube is arranged on the right side of the upper end of the detection box; the lower end of the dropping liquid needle tube is in butt joint communication with the sample adding position of the test paper; a puncture head is fixed at the upper end of the dropping needle tube; the side wall of the upper part of the dropping needle tube is provided with a through hole which is communicated with the outside; the right side of the upper end of the packaging box is provided with a connecting pipe; a sealing column is arranged in the connecting pipe; the lower sheet of the sealing column is fixedly connected with the upper end of the detection box; the dropping needle tube and the puncture head are inserted in the sealing column; the lower end of the reagent tube is in threaded sealing connection with the connecting tube; the sealing column is in plug-in sealing fit with the lower part in the reagent tube; a support ring is arranged at the lower part in the reagent tube; the upper end of the sealing column is in sealing contact with the support ring; the support ring is arranged above the connecting pipe; the inner diameter of the support ring is larger than the diameter of the sampling sac; the interior of the reagent tube is filled with a diluent.
Further optimizing the technical scheme, the left side of the upper end of an operating table of the special kit for screening the gastric precancerous lesions is provided with a storage box; the sampling capsule and the isolation paper are placed in the storage box.
Further optimizing the technical scheme, a protective rope is connected to a sampling capsule of the special kit for screening gastric precancerous lesions; the protective rope is sleeved with a protective film.
Further optimizes the technical proposal, and the side of the reagent tube of the special kit for screening gastric precancerous lesions is provided with a label.
Further optimizing the technical scheme, the right side of the upper end of an operating table of the special kit for screening gastric precancerous lesions is provided with a plurality of positioning seats; the detection box is connected with the positioning seat in an inserting way.
The invention has the beneficial effects that:
1. the sampling device can realize the closed sampling of a patient, reduce the mouth opening time, is beneficial to reducing the probability of respiratory diseases and virus infection, can realize the scraping of saliva and oral mucosa samples in the oral cavity at the same time, has rich sampling samples, is convenient for sampling according to the needs, is convenient for stimulating the generation of saliva when the sampling bag is in the oral cavity of the patient, is made of an elastic material, can store and carry the saliva of the patient in the sampling bag, can carry out the sampling scraping on the oral mucosa by latticed sampling strips, is matched with a permanent magnet for use, and has stronger scraping capacity;
the detection device can detect the sample diluent and can preserve the sample diluent at the same time. It is intraductal that sample bag enters into reagent after accomplishing the sample, release the sample and dilute the back, can add the application of sample department of test paper through the dropping liquid needle tubing and detect, and the detection zone of test paper can show the result, and reagent pipe is inside to dilute the sample and can preserve simultaneously, is convenient for detect once more or the persistence of sample. The test paper does not need to be in contact with the outside, the contact with the outside air is very little, and the test paper is stored in a sealed manner, is used in a sealed manner and has better storability;
2. the storage box can play a role in storage and preservation, and the stock is large;
3. the protective rope is connected with the sampling capsule, so that the patient can be prevented from swallowing the sampling capsule;
4. the permanent magnet can adsorb the sampling bag, the isolation rubber sleeve can be prevented from contacting with the skin of a patient due to the arrangement of the isolation paper, and the sampling bag can be prevented from contacting with the permanent magnet due to the isolation rubber sleeve;
5. the positioning seat is convenient for inserting and fixing the detection box, and is more stable.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the structure of a sampling capsule of the present invention;
FIG. 3 is a schematic plan view of the sampling capsule of the present invention;
FIG. 4 is a schematic plan view of the detecting device of the present invention;
FIG. 5 is a schematic view of a portion of the drip syringe of the present invention in use;
FIG. 6 is a schematic view of the protective rope structure of the present invention;
FIG. 7 is a schematic view of a label structure of the present invention;
in the figure, 1, an operation table; 2. a sampling capsule; 3. release paper; 4. a permanent magnet; 5. adsorbing cotton; 6. a sampling hole; 7. sampling a sample strip; 8. an isolation rubber sleeve; 9. a reagent tube; 10. a detection cartridge; 11. test paper; 12. a dropping needle tube; 13. a puncture head; 14. a through hole; 15. a connecting pipe; 16. sealing the column; 17. a support ring; 18. a storage box; 19. a protective rope; 20. a protective film; 21. a label; 22. a positioning seat.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
As shown in fig. 1-7, a special kit for screening gastric precancerous lesions comprises an operation table 1; a sampling device is arranged on the left side of the operating platform 1, and a detection device is arranged on the right side of the operating platform 1; the sampling device comprises a sampling bag 2, isolation paper 3 and a permanent magnet 4; the interior of the sampling bag 2 is filled with adsorption cotton 5; the surface of the sampling capsule 2 is provided with a plurality of sampling holes 6; the surface of the sampling bag 2 is provided with a latticed sampling strip 7; iron chips are filled in the side wall of the sampling bag 2; the end part of the permanent magnet 4 is sleeved with an isolation rubber sleeve 8; the detection device comprises a reagent tube 9 and a detection box 10; the test paper 11 is packaged in the detection box 10; the upper end of the detection box 10 is made of transparent material; a dropping needle tube 12 is arranged at the right side of the upper end of the detection box 10; the lower end of the dropping liquid needle tube 12 is in butt joint communication with the sample adding position of the test paper 11; a puncture head 13 is fixed at the upper end of the dropping needle tube 12; the side wall of the upper part of the dropping needle tube 12 is provided with a through hole 14 which is communicated with the outside; the right side of the upper end of the packaging box is provided with a connecting pipe 15; a sealing column 16 is arranged in the connecting pipe 15; the lower sheet of the sealing column 16 is fixedly connected with the upper end of the detection box 10; the dropping needle tube 12 and the puncture head 13 are inserted in the sealing column 16; the lower end of the reagent tube 9 is in threaded sealing connection with a connecting tube 15; the sealing column 16 is in plug-in sealing fit with the inner lower part of the reagent tube 9; a support ring 17 is arranged at the inner lower part of the reagent tube 9; the upper end of the sealing column 16 is in sealing contact with the support ring 17; the support ring 17 is above the connecting tube 15; the inner diameter of the supporting ring 17 is larger than the diameter of the sampling capsule 2; the reagent tube 9 is filled with diluent; a storage box 18 is arranged on the left side of the upper end of the operating platform 1; the sampling capsule 2 and the release paper 3 are placed in the storage box 18; the sampling bag 2 is connected with a protective rope 19; a protective film 20 is sleeved on the protective rope 19; the side surface of the reagent tube 9 is provided with a label 21; a plurality of positioning seats 22 are arranged on the right side of the upper end of the operating platform 1; the detecting box 10 is connected with the positioning seat 22 in a plugging manner.
When the device is used, the sampling device is used for collecting and sampling saliva in the oral cavity of a patient and scraping and sampling oral mucosa. After the patient gargles, sample bag 2 can be deposited in storage box 18, the independent packaging, directly put into the patient mouth after tearing, then the patient can close the mouth, for example patient can wear the gauze mask this moment, especially when having respiratory disease infectious risk, the patient can do the action of chewing to sample bag 2, be favorable to promoting the secretion of saliva, simultaneously when utilizing tooth to extrude sample bag 2 repeatedly, sample bag 2 is the repeated action of compression release, sample bag 2 self has the elasticity resilience ability, in the release process, self inside production negative pressure, the saliva in the oral cavity is absorb to accessible thief hole 6, the setting up of adsorbing cotton 5 is convenient for save saliva, it can be the line ball form to adsorb cotton 5, thief hole 6 diameter can be less, for example two millimeters in diameter. When needs scrape the oral mucosa and get, can be with the help of permanent magnet 4, 4 upper ends of permanent magnet cup joint isolation gum cover 8, barrier paper 3 is put on patient face one side, barrier paper 3 is disposable, then paste isolation gum cover 8 on barrier paper 3, the patient pushes sample bag 2 to 3 one sides of barrier paper, permanent magnet 4 is adsorbable to sample bag 2 this moment, patient face is pressed from the centre, can be at first push sample bag 2 to the tooth outside by the patient, adsorb down at magnetic force, sample bag 2 hugs closely on the oral mucosa, then isolation gum cover 8 keeps the laminating with the face, remove permanent magnet 4, then can drive sample bag 2 and scrape the oral mucosa, latticed sample strip 7 can improve the scraping ability, be adapted to any direction of scraping, latticed shape is convenient for persist the sample of scraping simultaneously. After the sample was accomplished, the patient can tell sample bag 2, can tell to keep apart gum cover 8 on, is adsorbed the location by permanent magnet 4, avoids dropping, then medical personnel can put into detection device with sample bag 2 and detect. The sampling capsule 2 can be placed in the reagent tube 9 and then the sampling capsule 2 is scraped off the isolating rubber sleeve 8 by a lateral movement and falls into the reagent tube 9.
The detection device is inverted, the detection box 10 is arranged on the upper portion, diluent in the reagent tube 9 is prevented from flowing out, the reagent tube 9 is detached from the connecting tube 15 and is placed into the sampling capsule 2, then the reagent tube 9 is hermetically connected with the connecting tube 15, and the sealing column 16 is hermetically matched with the inner lower portion of the reagent tube 9, so that sample preservation or culture can be realized. After the connection of the reagent vessel 9 is completed, the cassette 10 is again brought down and the reagent vessel 9 is brought up. The connecting portion of reagent pipe 9 and connecting pipe 15 is the stereoplasm material, and the rest is soft material, for example soft silica gel etc. can extrude sample bag 2 through extrusion reagent pipe 9, makes the sample fully mix with the diluent. Usable test paper 11 detects at last, there is the compression space between support ring 17 and the connecting pipe 15 upper end, namely the soft part of reagent pipe 9, medical personnel can pinch support ring 17 from the outside and extrude downwards, utilize support ring 17 compression sealing post 16, the pjncture needle can slowly pierce sealing post 16 upper portion this moment, the pjncture needle pierces through sealing post 16 after, continue to push down sealing post 16, can spill through-hole 14 of dropping liquid needle tubing 12, dropping liquid needle tubing 12 and the inside intercommunication of reagent pipe 9 this moment, can press in the application of sample department of test paper 11 through dropping liquid tubing 12 with a small amount of sample diluent through pressing, waiting time detects can, see through the transparent part in detection box 10 upper end, can observe test paper 11 detection zone. Because the dropping needle tube 12 is thin, and the detection box 10 is arranged in a closed manner and occupies the internal volume, excessive sample adding can not be caused. After the sample is added on the test paper 11, the reagent tube 9 is not extruded, the support ring 17 is released and is not pressed down, the sealing column 16 recovers under the self elastic recovery performance, the puncture needle and the dropping liquid needle tube 12 enter the sealing column 16 again, the puncture needle is thin, the destructiveness to the sealing column 16 is small, the puncture needle withdraws from the rear shell to recover, meanwhile, after the puncture needle returns to the sealing column 16, the sealing performance of the sealing column 16 is further ensured, and sample diluent in the reagent tube 9 can be stored. There is no need to immediately dispose of medical waste.
The isolation paper 3 is a disposable article, and the isolation rubber sleeve 8 is a single-use article, and can be reused after being sterilized or treated according to medical waste according to medical regulations.
The diluent stored in the reagent tube 9 may be other reagents necessary for sample processing.
Can connect on the sample bag 2 and set up protection rope 19, protection rope 19 is short but expose outside patient's oral cavity, but does not influence the patient and close the mouth, cup joints on the protection rope 19 and sets up protection film 20, can supply handheld the holding to hold and hold, can also directly hold between the fingers protection film 20 at last and place the sample bag 2 in the reagent pipe 9, can cut protection rope 19, also can put into the kit with protection rope 19 simultaneously, but protection film 20 breaks away from protection rope 19, and protection film 20 is according to medical waste treatment.
The end face of the isolation rubber sleeve 8 is contacted with the sampling capsule 2, and the end face can be set to be concave, so that the sampling capsule 2 can be conveniently received, and the outflow of sample saliva can be reduced.
When the invention is used, samples can be stored in the whole detection process and after detection, the reagent tube 9 can be stored for a long time, the label 21 can be arranged on the reagent tube 9 for identification, detection objects are not easy to mix, and the detection box 10 can be not marked.
The test paper 11 is arranged in the detection box 10 in a sealed mode, so that the storage effect is better, and the failure is not easy to occur. If the sample is invalid, the reagent tube 9 is only required to be matched with a new detection box 10 again, and the sample diluted liquid is dropped into the test paper 11 for detection according to the steps.
If a dark light environment is needed in the detection process, the positioning seat 22 can be arranged in a closed manner for the box body, after the detection box 10 is inserted, the interior of the detection box can be in a dark light or non-light environment, and the observation result is taken out after the detection time elapses.

Claims (5)

1. A special kit for screening gastric precancerous lesions is characterized in that: comprises an operation table (1); a sampling device is arranged on the left side of the operating platform (1), and a detection device is arranged on the right side of the operating platform (1); the sampling device comprises a sampling bag (2), isolation paper (3) and a permanent magnet (4); the interior of the sampling bag (2) is filled with adsorption cotton (5); the surface of the sampling bag (2) is provided with a plurality of sampling holes (6); the surface of the sampling bag (2) is provided with latticed sampling strips (7); scrap iron is filled in the side wall of the sampling bag (2); the end part of the permanent magnet (4) is sleeved with an isolation rubber sleeve (8); the detection device comprises a reagent tube (9) and a detection box (10); the test paper (11) is packaged in the detection box (10); the upper end of the detection box (10) is made of transparent material; a dropping needle tube (12) is arranged on the right side of the upper end of the detection box (10); the lower end of the dropping needle tube (12) is in butt joint communication with the sample adding position of the test paper (11); a puncture head (13) is fixed at the upper end of the dropping needle tube (12); the side wall of the upper part of the dropping needle tube (12) is provided with a through hole (14) which is communicated with the outside; the right side of the upper end of the packaging box is provided with a connecting pipe (15); a sealing column (16) is arranged in the connecting pipe (15); the lower end of the sealing column (16) is fixedly connected with the upper end of the detection box (10); the dropping needle tube (12) and the puncture head (13) are inserted in the sealing column (16); the lower end of the reagent tube (9) is in threaded sealing connection with the connecting tube (15); the sealing column (16) is in plug-in sealing fit with the inner lower part of the reagent tube (9); a support ring (17) is arranged at the inner lower part of the reagent tube (9); the upper end of the sealing column (16) is in sealing contact with the support ring (17); the support ring (17) is arranged above the connecting pipe (15); the inner diameter of the supporting ring (17) is larger than the diameter of the sampling capsule (2); the reagent tube (9) is filled with a diluent.
2. The kit for screening gastric precancerous lesion as claimed in claim 1, wherein: a storage box (18) is arranged on the left side of the upper end of the operating platform (1); the sampling capsule (2) and the isolation paper (3) are placed in a storage box (18).
3. The kit for screening gastric precancerous lesion as claimed in claim 1, wherein: the sampling bag (2) is connected with a protective rope (19); the protective film (20) is sleeved on the protective rope (19).
4. The kit for screening gastric precancerous lesion as claimed in claim 1, wherein: the side surface of the reagent tube (9) is provided with a label (21).
5. The kit for screening gastric precancerous lesion as claimed in claim 1, wherein: a plurality of positioning seats (22) are arranged on the right side of the upper end of the operating platform (1); the detection box (10) is connected with the positioning seat (22) in an inserting way.
CN202010394089.XA 2020-05-11 2020-05-11 Special kit for screening gastric precancerous lesions Withdrawn CN111521802A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010394089.XA CN111521802A (en) 2020-05-11 2020-05-11 Special kit for screening gastric precancerous lesions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010394089.XA CN111521802A (en) 2020-05-11 2020-05-11 Special kit for screening gastric precancerous lesions

Publications (1)

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CN111521802A true CN111521802A (en) 2020-08-11

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CN202010394089.XA Withdrawn CN111521802A (en) 2020-05-11 2020-05-11 Special kit for screening gastric precancerous lesions

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111929442A (en) * 2020-08-13 2020-11-13 北京测尔康生物技术有限公司 Novel coronavirus antigen and antibody detection kit

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111929442A (en) * 2020-08-13 2020-11-13 北京测尔康生物技术有限公司 Novel coronavirus antigen and antibody detection kit

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Application publication date: 20200811

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