CN111514950A - 使用分离液进行样品浓缩和检测的系统和方法 - Google Patents

使用分离液进行样品浓缩和检测的系统和方法 Download PDF

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Publication number
CN111514950A
CN111514950A CN202010346415.XA CN202010346415A CN111514950A CN 111514950 A CN111514950 A CN 111514950A CN 202010346415 A CN202010346415 A CN 202010346415A CN 111514950 A CN111514950 A CN 111514950A
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China
Prior art keywords
sample
microcavity
container
filter
sample detection
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Pending
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CN202010346415.XA
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English (en)
Chinese (zh)
Inventor
R·拉亚戈帕尔
K·J·哈尔威森
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3M Innovative Properties Co
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3M Innovative Properties Co
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • B01L3/50215Test tubes specially adapted for centrifugation purposes using a float to separate phases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0605Metering of fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0631Purification arrangements, e.g. solid phase extraction [SPE]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0642Filling fluids into wells by specific techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0832Geometry, shape and general structure cylindrical, tube shaped
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0893Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202010346415.XA 2013-12-20 2014-12-16 使用分离液进行样品浓缩和检测的系统和方法 Pending CN111514950A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361919001P 2013-12-20 2013-12-20
US61/919,001 2013-12-20
CN201480068898.4A CN105828948A (zh) 2013-12-20 2014-12-16 使用分离液进行样品浓缩和检测的系统和方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480068898.4A Division CN105828948A (zh) 2013-12-20 2014-12-16 使用分离液进行样品浓缩和检测的系统和方法

Publications (1)

Publication Number Publication Date
CN111514950A true CN111514950A (zh) 2020-08-11

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CN202010346415.XA Pending CN111514950A (zh) 2013-12-20 2014-12-16 使用分离液进行样品浓缩和检测的系统和方法
CN201480068898.4A Pending CN105828948A (zh) 2013-12-20 2014-12-16 使用分离液进行样品浓缩和检测的系统和方法

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Country Status (5)

Country Link
US (1) US10639629B2 (https=)
EP (1) EP3083055A1 (https=)
JP (1) JP2017503639A (https=)
CN (2) CN111514950A (https=)
WO (1) WO2015095145A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115069430A (zh) * 2022-06-25 2022-09-20 烟台罗博特智能设备有限公司 一种酵母用离心机控制方法、系统、装置及存储介质

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10639628B2 (en) 2013-12-20 2020-05-05 3M Innovative Properties Company Systems and methods for sample concentration and detection
FR3018203B1 (fr) * 2014-03-10 2017-12-01 Cummins Filtration Sarl Ensemble de filtrage comportant une cartouche de filtration
EP3380218B1 (en) * 2015-11-27 2025-04-23 Merck Patent GmbH Membrane support and membrane filtration device
WO2017205778A1 (en) * 2016-05-27 2017-11-30 Biomerieux, Inc. Method and apparatus for detection of foam in specimen containers
CN110062881A (zh) * 2016-12-09 2019-07-26 3M创新有限公司 用于快速检测感兴趣分析物的系统和方法
EP3611508B1 (en) * 2017-05-16 2022-08-03 SK Telecom Co., Ltd. Nucleic acid analysis apparatus using catridge
EP3624691B1 (en) * 2017-05-17 2025-08-06 Radiometer Medical ApS Porous optical fiber for the detection of an analyte in a fluid
US10527171B2 (en) * 2017-08-15 2020-01-07 Cellular Research, Inc. Gasket
US11446663B2 (en) * 2018-01-26 2022-09-20 Aincobio Llc Method and apparatus for isolating and detecting biological and other particles
CN108906348B (zh) * 2018-03-05 2023-10-10 中国标准化研究院 分离土壤中微塑料和纤维素结晶的分离装置及分离方法
CN108442927B (zh) * 2018-03-12 2020-05-01 中国地质大学(北京) 现场录井应用的岩屑孔隙度测量方法、测量装置和应用
EP3546916A1 (en) * 2018-03-26 2019-10-02 Spaziani Rolando S.R.L. Two-stage cap for ambient air sampling vials
JP7477458B2 (ja) 2018-04-05 2024-05-01 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング フィルターシステム用の濾過ヘッドおよび濾過ヘッドと組み合わせて使用するための漏斗
CA3108720A1 (en) 2018-08-22 2020-02-27 Biomerieux, Inc. Detection instruments with automated cell location selection for newly intaken specimen containers and related methods
CN110548304A (zh) * 2019-09-07 2019-12-10 天津药明康德新药开发有限公司 用于移除沸点溶剂的离心浓缩仪
CN110819687A (zh) * 2019-10-24 2020-02-21 广东环凯生物科技有限公司 一种大肠杆菌o157免疫磁珠洗液
CN112570154B (zh) * 2021-02-24 2024-03-19 英诺维尔智能科技(苏州)有限公司 一种离心换液装置
EP4166247A1 (en) * 2021-10-12 2023-04-19 Getinge Lancer SAS Industrial washer with exhaust system
DE102021006144A1 (de) * 2021-12-13 2023-06-15 BlueCat Solutions GmbH Reaktionsgefäßeinheit, Verfahren zum selektiven Entfernen einer Flüssigkeit sowie zum Einbringen einer einen Zielstoff enthaltenden Flüssigkeit aus einem bzw. in ein Reaktionsgefäß einer Reaktionsgefäßeinheit
CN116559411B (zh) * 2023-05-18 2026-02-24 弗艾博浆纸科技发展(广东)有限公司 一种动态滤水性及留着率测定仪
CN117405478B (zh) * 2023-10-19 2024-09-17 中国地质科学院矿产综合利用研究所 一种土壤中微塑料的提取方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005456A1 (en) * 1987-12-01 1989-06-15 Biotope, Inc. Methods and devices for conducting assays
WO2013003309A1 (en) * 2011-06-30 2013-01-03 3M Innovative Properties Company Systems and methods for detecting an analyte of interest in a sample using filters and microstructured surfaces

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212948A (en) * 1978-10-18 1980-07-15 J. K. And Susie L. Wadley Research Institute And Blood Bank Apparatus for detecting microbial pathogens employing a cushioning agent
US4539256A (en) 1982-09-09 1985-09-03 Minnesota Mining And Manufacturing Co. Microporous sheet material, method of making and articles made therewith
US4726989A (en) 1986-12-11 1988-02-23 Minnesota Mining And Manufacturing Microporous materials incorporating a nucleating agent and methods for making same
DE3722562A1 (de) * 1987-07-08 1989-01-19 Andreas Szabados Ringfoermiger filterkoerper
US4867881A (en) 1987-09-14 1989-09-19 Minnesota Minning And Manufacturing Company Orientied microporous film
US4959301A (en) 1988-04-22 1990-09-25 Massachusetts Institute Of Technology Process for rapidly enumerating viable entities
US5120594A (en) 1989-11-20 1992-06-09 Minnesota Mining And Manufacturing Company Microporous polyolefin shaped articles with patterned surface areas of different porosity
US5260360A (en) 1991-10-18 1993-11-09 Minnesota Mining And Manufacturing Company Oil, water and sweat repellent microporous membrane materials
US5716798A (en) 1992-09-22 1998-02-10 Becton Dickinson And Company Enhanced detection of microorganisms in samples
CA2179364C (en) 1995-06-27 1999-09-28 Klaus W. Berndt Method and apparatus for detecting microorganisms
US5833860A (en) 1995-08-28 1998-11-10 Millipore Investment Holdings Limited Centrifugal adsorptive sample preparation device and method
US5888594A (en) 1996-11-05 1999-03-30 Minnesota Mining And Manufacturing Company Process for depositing a carbon-rich coating on a moving substrate
US6391578B2 (en) 1997-04-09 2002-05-21 3M Innovative Properties Company Method and devices for partitioning biological sample liquids into microvolumes
US6420622B1 (en) 1997-08-01 2002-07-16 3M Innovative Properties Company Medical article having fluid control film
CA2329011A1 (en) 1998-04-29 1999-11-04 3M Innovative Properties Company Receptor sheet for inkjet printing having an embossed surface
US6221655B1 (en) 1998-08-01 2001-04-24 Cytosignal Spin filter assembly for isolation and analysis
US7223364B1 (en) 1999-07-07 2007-05-29 3M Innovative Properties Company Detection article having fluid control film
US7781159B2 (en) 2002-05-09 2010-08-24 Nanologix, Inc. Micromethod and device for rapid detection, enumeration and identification of entities
US8361783B2 (en) 2002-05-09 2013-01-29 Nanologix, Inc. Micromethod and device for the rapid detection, enumeration and identification of microorganisms
US20030235677A1 (en) 2002-06-25 2003-12-25 3M Innovative Properties Company Complex microstructure film
US20030235678A1 (en) 2002-06-25 2003-12-25 Graham Paul D. Complex microstructure film
EP1608952B1 (en) * 2002-12-20 2016-08-10 Life Technologies Corporation Assay apparatus and method using microfluidic arrays
US7524623B2 (en) 2003-07-28 2009-04-28 Nanologix, Inc. Method and device for rapid detection of microorganisms by changing the shape of micro-colonies
US7582472B2 (en) 2003-08-26 2009-09-01 Smith Kenneth E Apparatus and method for liquid sample testing
US20070134784A1 (en) 2005-12-09 2007-06-14 Halverson Kurt J Microreplicated microarrays
DE102006022877B4 (de) 2006-05-15 2009-01-29 Sartorius Stedim Biotech Gmbh Verfahren zur Bestimmung der Viabilität von Zellen in Zellkulturen
EP2046940A4 (en) 2006-06-26 2011-08-10 Life Technologies Corp HEATED COVERING PROCESSES AND TECHNOLOGY
CN101566389A (zh) 2008-04-24 2009-10-28 沈阳东方钢铁有限公司 卧式高温热风炉
US20100015690A1 (en) 2008-07-16 2010-01-21 Ortho-Clinical Diagnostics, Inc. Use of fluid aspiration/dispensing tip as a microcentrifuge tube
KR20110091719A (ko) * 2008-10-31 2011-08-12 바이오메리욱스, 인코포레이티드. 식별제를 사용한 미생물의 분리 및 특성규명 방법
BRPI0922320A2 (pt) 2008-12-19 2016-01-05 3M Innovative Properties Co material microporoso de um copolímero de etileno - cloro trifluoroetileno e método para a produção do mesmo
EP2373975B1 (en) 2008-12-19 2020-04-01 3M Innovative Properties Company System and method for processing samples
CN102301220B (zh) 2008-12-19 2014-06-25 3M创新有限公司 用于浓缩样品的系统和方法
BRPI0923737A2 (pt) 2008-12-31 2016-01-19 3M Innovative Properties Co "membranas porosas com múltiplas zonas que têm tamanhos de poro diferentes".
CA2777146A1 (en) 2009-10-16 2011-04-21 Sanofi-Aventis Deutschland Gmbh Arrangement for use in a drug delivery device
WO2011063332A2 (en) 2009-11-23 2011-05-26 3M Innovative Properties Company Microwell array articles and methods of use
US8585905B2 (en) 2010-02-26 2013-11-19 Waters Technologies Corporation Devices, kits and methods for performing chemical processing
US20130109262A1 (en) 2010-06-01 2013-05-02 3M Innovative Properties Company Coated porous materials
WO2011153085A2 (en) 2010-06-01 2011-12-08 3M Innovative Properties Company Process for making coated porous materials
CA2801894A1 (en) 2010-06-07 2011-12-15 3M Innovative Properties Company Filtration methods and devices
EP2576812A1 (en) 2010-06-07 2013-04-10 3M Innovative Properties Company Filtration methods and devices
EP2726842B1 (en) 2011-06-30 2016-03-16 3M Innovative Properties Company Systems and methods for detecting an analyte of interest in a sample using microstructured surfaces
US10639628B2 (en) 2013-12-20 2020-05-05 3M Innovative Properties Company Systems and methods for sample concentration and detection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005456A1 (en) * 1987-12-01 1989-06-15 Biotope, Inc. Methods and devices for conducting assays
WO2013003309A1 (en) * 2011-06-30 2013-01-03 3M Innovative Properties Company Systems and methods for detecting an analyte of interest in a sample using filters and microstructured surfaces

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115069430A (zh) * 2022-06-25 2022-09-20 烟台罗博特智能设备有限公司 一种酵母用离心机控制方法、系统、装置及存储介质
CN115069430B (zh) * 2022-06-25 2023-06-16 烟台罗博特智能设备有限公司 一种酵母用离心机控制方法、系统、装置及存储介质

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Publication number Publication date
CN105828948A (zh) 2016-08-03
US10639629B2 (en) 2020-05-05
US20160310941A1 (en) 2016-10-27
JP2017503639A (ja) 2017-02-02
WO2015095145A1 (en) 2015-06-25
EP3083055A1 (en) 2016-10-26

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Application publication date: 20200811