CN111514945A - Biomarker of tumor, application and tumor detection kit - Google Patents
Biomarker of tumor, application and tumor detection kit Download PDFInfo
- Publication number
- CN111514945A CN111514945A CN202010403787.1A CN202010403787A CN111514945A CN 111514945 A CN111514945 A CN 111514945A CN 202010403787 A CN202010403787 A CN 202010403787A CN 111514945 A CN111514945 A CN 111514945A
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- tumor
- biomarker
- kit
- fixedly connected
- detection kit
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 30
- 238000001514 detection method Methods 0.000 title claims abstract description 19
- 239000000090 biomarker Substances 0.000 title claims abstract description 11
- 239000007788 liquid Substances 0.000 claims description 14
- 210000005056 cell body Anatomy 0.000 claims description 10
- 239000000107 tumor biomarker Substances 0.000 claims description 9
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 28
- 238000002474 experimental method Methods 0.000 abstract description 3
- 208000002154 non-small cell lung carcinoma Diseases 0.000 description 4
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 4
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 201000005202 lung cancer Diseases 0.000 description 3
- 208000020816 lung neoplasm Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000009456 molecular mechanism Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L1/00—Enclosures; Chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0289—Apparatus for withdrawing or distributing predetermined quantities of fluid
- B01L3/0293—Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a biomarker of tumor, application and a tumor detection kit, relates to the field of detection kit devices, and aims at the characteristics that the existing tumor detection kit is low in dropping reagent and cannot conveniently replace the reagent, so that the efficiency of an experiment is greatly reduced. The device has the characteristics that reagents can be conveniently and efficiently dripped, the specimen tray can be conveniently pulled in and pulled out, and the specimen tray can be conveniently and efficiently replaced.
Description
Technical Field
The invention relates to the field of detection kit devices, in particular to a biomarker of tumor, application and a tumor detection kit.
Background
Cancer is currently the most significant disease in global mortality and incidence, with over 85% being non-small cell lung cancer (NSCLC). Traditional chemotherapy has limited efficacy in treating non-small cell lung cancer, and median survival after diagnosis is often less than one year. In recent years, the research on the molecular mechanism of lung cancer has been advanced greatly, the molecular typing of lung cancer is determined, and a targeting drug suitable for the target spot is selected, so that a satisfactory curative effect can be obtained for the treatment of non-small cell lung cancer.
The existing device can not conveniently detect the lung cancer, and the severe cancer is detected and a laboratory generally needs to carry out multi-section tests, and the reagent is required to be dripped on the sections to carry out different observations during the tests, but the existing sections can be dripped one by one when the reagent is dripped, so that the working efficiency is greatly reduced.
In addition, in the actual use process of the existing kit, different reagents cannot be added dropwise conveniently, and different reagents need to be cleaned and replaced when being added dropwise, so that the experiment efficiency is greatly reduced. Therefore, a tumor biomarker, an application and a tumor detection kit are provided.
Disclosure of Invention
The tumor biomarker, the application and the tumor detection kit provided by the invention solve the problems that the existing tumor detection kit has the characteristics of low efficiency in reagent dripping and incapability of conveniently replacing the reagent, and greatly reduces the experiment efficiency.
In order to achieve the purpose, the invention adopts the following technical scheme:
a biomarker for tumors, an application and a tumor detection kit comprise a kit body, wherein a first groove body and a second groove body are respectively arranged on the left side and the right side of the kit body from top to bottom, the kit body is arranged in the first groove body, a specimen tray is arranged in the second groove body, the left side and the right side of each kit body are fixedly connected with a connecting block, the inner walls of the left side and the right side of each first groove body are respectively provided with a first chute, a slide bar is fixedly connected between the upper inner wall and the lower inner wall of the front side and the rear side of each first chute, the surface of each slide bar is sleeved with a tension spring, a transverse plate is arranged in each first chute, a bottom plate is arranged on the inner bottom wall of each first groove body, a spring is arranged between the bottom plate and the lower inner wall of the first groove body, a plurality of drip heads are arranged on the lower surface of the bottom plate, and a screw rod is arranged on one side, two the cavity has all been seted up to one side that the second cell body is close to each other, two the equal fixedly connected with bevel gear of one end that the screw rod is close to each other, every the top of cavity all is provided with first motor, and the same bevel gear of output fixedly connected with of first motor.
Preferably, the upper surface of the kit is provided with a liquid squeezing button, and the center of the upper surface of the transverse plate is fixedly connected with an arc-shaped pulling block.
Preferably, each transverse plate is connected in the first sliding groove in a sliding mode, and the front end and the rear end of each transverse plate are sleeved on the surfaces, provided with the sliding rods, of the front side and the rear side of the first sliding groove in a sliding mode.
Preferably, each connecting block is fastened and connected with the upper surface of the transverse plate through a bolt.
Preferably, every the lower extreme of dripper all passes the interior diapire of first cell body, extends in the top of second cell body, the upper end setting of dripper is at the upper surface of bottom plate, and with the lower surface cooperation of kit is connected.
Preferably, every slide has all been seted up to preceding, the back inner wall of second cell body, every the equal fixedly connected with slider of preceding, the back both sides face of sample tray, slider sliding connection is in the slide.
Preferably, every the equal threaded connection of screw rod is in the center of the sample tray of self one side, and the one end of keeping away from the sample tray extends in the cavity, and extends the surface of end and cup jointed bevel gear, the bevel gear of screw rod surface suit is connected with the bevel gear meshing of first motor output fixed connection.
Compared with the prior art, the invention has the beneficial effects that:
through the box body, the first groove body, the second groove body, the reagent box, the sample tray, the connecting block, the first sliding chute, the sliding rod, the tension spring, the transverse plate, the bottom plate, the spring, the liquid dropping head, the conical gear, the cavity and the screw rod, the device can be fixedly connected between the connecting block and the transverse plate which are fixedly connected with the left side and the right side of the reagent box through the bolts, so that the transverse plate can be pulled under the action of the tension spring to further pull the reagent box to move downwards, the lower surface of the reagent box is connected with the bottom plate in a fitting manner, the upper end of the liquid dropping head can be connected with the lower surface of the reagent box in a matching manner, the liquid guiding is convenient, the screw rod is sleeved with the sample tray through the threads between the screw rod and the sample tray, the screw rod can be driven to rotate through the meshing connection of the two conical gears under the driving of the first motor, therefore, when the specimen trays with different densities are handled, the bottom plate can be conveniently replaced.
Make this device have can make things convenient for the efficient to carry out dropwise add reagent, and can be convenient pull in and pull out the sample tray, and change that can be convenient is used for carrying out the operation of dropwise add reagent to the sample tray of difference.
Drawings
FIG. 1 is a cross-sectional view of the structure of a biomarker for a tumor according to the present invention.
FIG. 2 is a cross-sectional view of a side-view structure of a biomarker of a tumor of the present invention.
Fig. 3 is a cross-sectional view of a top view of a tumor biomarker of the present invention.
Reference numbers in the figures: the kit comprises a box body 1, a first groove body 2, a second groove body 3, a kit 4, a specimen tray 5, a connecting block 6, a first sliding groove 7, a sliding rod 8, a tension spring 9, a transverse plate 10, a bottom plate 11, a spring 12, a liquid dropper 13, a bevel gear 14, a cavity 15 and a screw rod 16.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Referring to fig. 1-3, a biomarker, an application and a tumor detection kit for tumor, comprising a kit body 1, wherein a first trough body 2 and a second trough body 3 are respectively arranged on the left side and the right side of the kit body 1 from top to bottom, a kit 4 is arranged in the first trough body 2, a specimen tray 5 is arranged in the second trough body 3, connecting blocks 6 are fixedly connected with the left side and the right side of each kit 4, a first chute 7 is arranged on the inner wall of the left side and the right side of each first trough body 2, a slide bar 8 is fixedly connected between the upper inner wall and the lower inner wall of the front side and the rear side of each first chute 7, a tension spring 9 is sleeved on the surface of each slide bar 8, a transverse plate 10 is arranged in each first chute 7, a bottom plate 11 is arranged on the inner bottom wall of the first trough body 2, a spring 12 is arranged between the bottom plate 11 and the lower inner wall of the first trough body 2, two left and right specimen trays 5 one side that is close to each other all is provided with screw rod 16, and cavity 15 has all been seted up to one side that two second cell bodies 3 are close to each other, and the equal fixedly connected with bevel gear 14 of one end that two screw rods 16 are close to each other, and the top of every cavity 15 all is provided with first motor, and the same bevel gear 14 of the output fixedly connected with of first motor.
In this embodiment, the upper surface of the reagent kit 4 is provided with a liquid squeezing button, and the center of the upper surface of the horizontal plate 10 is fixedly connected with an arc-shaped pulling block.
In this embodiment, each transverse plate 10 is slidably connected in the first sliding groove 7, and the front and rear ends of each transverse plate 10 are slidably sleeved on the surfaces of the first sliding groove 7 on which the sliding rods 8 are disposed.
In this embodiment, each connecting block 6 is fastened and connected with the upper surface of the transverse plate 10 through a bolt, a plurality of rubber openings are formed in the lower surface of the reagent box 4, a dropper is arranged in the dropper 13 on the bottom plate 11, and when the reagent box 4 is connected with the dropper 13 on the bottom plate 11 in a matching manner, reagents in the reagent box 4 can be extruded out through the extrusion liquid extrusion button.
In this embodiment, the lower end of each liquid dropper 13 penetrates through the inner bottom wall of the first tank body 2 and extends above the second tank body 3, and the upper end of each liquid dropper 13 is arranged on the upper surface of the bottom plate 11 and is connected with the lower surface of the reagent kit 4 in a matching manner.
In this embodiment, the slide way has all been seted up to the preceding, the back inner wall of every second cell body 3, and the equal fixedly connected with slider of the preceding, the back both sides face of every sample tray 5, slider sliding connection is in the slide way.
In this embodiment, each screw 16 is screwed in the center of the specimen tray 5 on one side of the screw, one end of the screw, which is far away from the specimen tray 5, extends into the cavity 15, the surface of the extending end is sleeved with the bevel gear 14, and the bevel gear 14 sleeved on the surface of the screw 16 is meshed with the bevel gear 14 fixedly connected with the output end of the first motor.
The working principle is as follows: when the device is used, the transverse plate 10 can be lifted upwards by pulling the arc-shaped pulling block fixedly connected with the upper surface of the transverse plate 10, the connecting block 6 fixedly connected with the left side and the right side of the reagent kit 4 is fixedly connected with the transverse plate 10 through the bolt, the transverse plate 10 can be pulled to pull the reagent kit 4 to move downwards under the action of the tension spring 9, the lower surface of the reagent kit 4 is connected with the bottom plate 11 in a fit manner, the upper end of the dropping liquid head 13 can be connected with the lower surface of the reagent kit in a matched manner, liquid guiding is convenient, moisture installation and replacement can be conveniently carried out due to the direct bolt connection of the reagent kit 4 and the transverse plate 10, the transverse plate 10 can be directly pushed out under the action of the spring 12 after the reagent kit 4 is taken down, the bottom plate 11 can be conveniently replaced, the screw rod 16 can be driven to rotate through the meshing connection of the two bevel gears 14 under the driving of the first motor, and then can promote sample tray 5 and slide in and the roll-off second cell body 3, made things convenient for to get and put, and because be provided with a plurality of liquid droppers 13 on the bottom plate 11, consequently when dealing with sample tray 5 of different density, also can be convenient change bottom plate 11 for it can to change bottom plate 11 that is provided with different density liquid droppers 13.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (7)
1. A biomarker, application and tumor detection kit for tumors comprises a kit body (1), wherein a first groove body (2) and a second groove body (3) are respectively arranged on the left side and the right side of the kit body (1) from top to bottom, and is characterized in that a kit (4) is arranged in the first groove body (2), a specimen tray (5) is arranged in the second groove body (3), the left side and the right side of each kit (4) are fixedly connected with connecting blocks (6), the inner walls of the left side and the right side of each first groove body (2) are respectively provided with a first sliding chute (7), a sliding rod (8) is fixedly connected between the upper inner wall and the lower inner wall of the front side and the rear side of each first sliding chute (7), the surface of each sliding rod (8) is sleeved with a tension spring (9), and a transverse plate (10) is arranged in each first sliding chute (7), the inner bottom wall of first cell body (2) is provided with bottom plate (11), be provided with spring (12) between the lower inner wall of bottom plate (11) and first cell body (2), the lower surface of bottom plate (11) is provided with a plurality of drippers (13), left and right two one side that sample tray (5) are close to each other all is provided with screw rod (16), two cavity (15), two have all been seted up to one side that second cell body (3) are close to each other the equal fixedly connected with conical gear (14) of one end that screw rod (16) are close to each other, every the top of cavity (15) all is provided with first motor, and the same conical gear (14) of the output fixedly connected with of first motor.
2. The tumor biomarker, the tumor application and the tumor detection kit according to claim 1, wherein a liquid squeezing button is arranged on the upper surface of the kit (4), and an arc-shaped pull block is fixedly connected to the center of the upper surface of the transverse plate (10).
3. The tumor biomarker, the tumor detection kit and the application of the tumor biomarker according to claim 1, wherein each of the horizontal plates (10) is slidably connected in the first sliding groove (7), and the front end and the rear end of each of the horizontal plates (10) are slidably sleeved on the surfaces of the first sliding groove (7) on which the sliding bars (8) are disposed.
4. The tumor biomarker, application and tumor detection kit according to claim 1, wherein each connecting block (6) is fixedly connected with the upper surface of the transverse plate (10) through a bolt.
5. The tumor biomarker, the tumor biomarker application and the tumor detection kit according to claim 1, wherein the lower end of each dripper (13) penetrates through the inner bottom wall of the first tank body (2) and extends above the second tank body (3), and the upper end of each dripper (13) is arranged on the upper surface of the bottom plate (11) and is connected with the lower surface of the kit (4) in a matching manner.
6. The biomarker, the application and the tumor detection kit of claim 1, wherein slide ways are formed in the front and rear inner walls of each second groove body (3), slide blocks are fixedly connected to the front and rear side faces of each specimen tray (5), and the slide blocks are slidably connected in the slide ways.
7. The biomarker, the application and the tumor detection kit for the tumor according to claim 1, wherein each screw (16) is screwed in the center of the specimen tray (5) on one side of the screw, one end of the screw, which is far away from the specimen tray (5), extends in the cavity (15), a bevel gear (14) is sleeved on the surface of the extending end, and the bevel gear (14) sleeved on the surface of the screw (16) is in meshed connection with the bevel gear (14) fixedly connected with the output end of the first motor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010403787.1A CN111514945B (en) | 2020-05-13 | 2020-05-13 | Tumor detection kit containing tumor biomarkers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010403787.1A CN111514945B (en) | 2020-05-13 | 2020-05-13 | Tumor detection kit containing tumor biomarkers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111514945A true CN111514945A (en) | 2020-08-11 |
| CN111514945B CN111514945B (en) | 2022-06-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010403787.1A Expired - Fee Related CN111514945B (en) | 2020-05-13 | 2020-05-13 | Tumor detection kit containing tumor biomarkers |
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| Country | Link |
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| CN (1) | CN111514945B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112630453A (en) * | 2020-12-23 | 2021-04-09 | 贵州金域医学检验中心有限公司 | Constant temperature kit for gynecological tumor marker detection and detection method thereof |
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| CN209167322U (en) * | 2018-11-26 | 2019-07-26 | 张文杰 | A kind of neoplastic hematologic disorder analysis of markers device |
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2020
- 2020-05-13 CN CN202010403787.1A patent/CN111514945B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010078601A1 (en) * | 2009-01-05 | 2010-07-08 | The Regents Of The University Of California | High throughput biomolecule separation and analysis |
| CN205484377U (en) * | 2016-03-24 | 2016-08-17 | 三诺生物传感股份有限公司 | Detection kit |
| CN207923892U (en) * | 2017-12-29 | 2018-09-28 | 广州益威恩生物科技有限责任公司 | A kind of animal brucella antibody gold labeled quick detection reagent box |
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| CN112630453A (en) * | 2020-12-23 | 2021-04-09 | 贵州金域医学检验中心有限公司 | Constant temperature kit for gynecological tumor marker detection and detection method thereof |
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| Publication number | Publication date |
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| CN111514945B (en) | 2022-06-21 |
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