CN111467426A - Traditional Chinese medicine patch for moistening lung to arrest cough and preparation method thereof - Google Patents

Traditional Chinese medicine patch for moistening lung to arrest cough and preparation method thereof Download PDF

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CN111467426A
CN111467426A CN202010364491.3A CN202010364491A CN111467426A CN 111467426 A CN111467426 A CN 111467426A CN 202010364491 A CN202010364491 A CN 202010364491A CN 111467426 A CN111467426 A CN 111467426A
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patch
chinese medicine
cough
vinegar
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CN111467426B (en
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王凯铭
郜菲
艾方磊
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Beijing Huimin Traditional Chinese Medicine Children's Hospital Co ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine patch for moistening lung and relieving cough, which comprises the following traditional Chinese medicinal materials: mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut. The invention also provides a preparation method of the traditional Chinese medicine patch. The traditional Chinese medicine patch is suitable for preventing and/or treating infantile cough, expectoration, pharyngalgia or pharynx itch.

Description

Traditional Chinese medicine patch for moistening lung to arrest cough and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine patch for moistening lung to arrest cough and a preparation method thereof.
Background
The infantile cough is a common disease in clinical medicine, and the main symptoms of the infantile cough comprise rhinorrhea, dry and itchy pharynx, cough with little phlegm and the like. The traditional Chinese medicine considers that the disease is frequently encountered by children in spring and autumn, because the season belongs to the main causes of wind evil and dryness evil, the lung of the children is tender and is easy to be invaded by pathogenic qi to cause the lung to lose the function of dispersing and purifying, and the qi movement is disordered to cause cough. The cough can be treated by western medicine and traditional Chinese medicine at present, and the western medicine treatment scheme is as follows: diet and work and rest guidance, rest, diet and indoor temperature adjustment; the drug therapy can be used for administering expectorant such as ambroxol, acetylcysteine and carbocisteine when cough frequently obstructs rest, and for administering bronchodilator when spasm of trachea occurs. The traditional Chinese medicine treatment scheme is divided into internal treatment and external treatment. The internal treatment is mainly oral decoction, and the treatment is dialectically performed under the guidance of the basic theory of traditional Chinese medicine, and the medicines are taken according to a great method and a great prescription based on dispelling exogenous pathogenic factors and ventilating lung qi. The external treatment is mainly infant massage and acupoint application, and is used for stimulating meridian points to achieve the purposes of ventilating lung and relieving cough.
Patent document CN103933435A discloses a medicine for effectively treating dry cough, which is prepared from mulberry leaf, radix glehniae and thunberg fritillary bulb by combining with other traditional Chinese medicines, and is suitable for treating dry cough caused by dryness-evil affecting the lung, lung failing to disperse and descend, yin deficiency, lung dryness, dysfunction in clearing and purifying, fluid accumulation and phlegm coagulation, liver-stomach disharmony, qi movement adverse rising and liver-yin deficiency.
Patent document CN108143904A discloses a medicine for treating hyperthyroidism, which is prepared from thunberg fritillary bulb, Chinese gall and Chinese magnoliavine fruit in combination with other traditional Chinese medicines, and is suitable for treating hyperthyroidism.
Patent document CN108853330A discloses a medicament for treating meningitis, which is prepared from mulberry leaf, radix glehniae and schisandra chinensis in combination with other traditional Chinese medicines, and has a remarkable curative effect on meningitis through clinical verification.
Therefore, no prior art related to the application of mulberry leaves, radix glehniae, thunberg fritillary bulb, schisandra chinensis and gallnuts in treating cough is reported at present.
The present invention has been made in view of the above circumstances.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine patch for moistening lung to arrest cough, which has the advantages of good curative effect, simple preparation and no toxic or side effect.
In order to realize the purpose of the invention, the invention provides a traditional Chinese medicine patch for moistening lung and relieving cough, which comprises the following traditional Chinese medicinal materials: mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut. The vinegar schisandra chinensis is prepared by taking schisandra chinensis as a raw material according to a legal processing method in Chinese pharmacopoeia.
Further optionally, the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 1-3: 1-3: 1-3: 1-3 of mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
Further optionally, the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 1: 1: 1: 1 mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
Further optionally, the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 3: 3: 2: 1 mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
Further optionally, the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 2: 1: 1: 2 mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
Further optionally, the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 1: 2: 3: 3 mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
Further optionally, the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 2: 2: 2: 2 mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut. .
In one embodiment of the invention, the traditional Chinese medicine patch is prepared from the following raw materials in a weight ratio of 1: 1-3: 1-3: 1-3: 1-3 of mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
The invention also provides a preparation method of the traditional Chinese medicine patch for moistening lung to arrest cough, which comprises the following steps:
weighing mulberry leaves, radix glehniae, thunberg fritillary bulb, vinegar-processed schisandra chinensis and gallnut according to parts by weight, cleaning, drying, crushing and sieving the medicinal materials to obtain medicinal material powder; adding rice vinegar into the medicinal powder, blending into paste to obtain dressing, and placing the dressing on a carrier to obtain the patch.
Further optionally, the drying temperature is 50-60 deg.C, and the drying time is 30-40 min.
Preferably, the drying temperature is 55-60 ℃, and the drying time is 30-35 min.
Further optionally, sieving the pulverized medicinal materials with 50-100 mesh sieve.
Preferably, the pulverized medicinal material is sieved by a 80-mesh sieve.
Further optionally, pharmaceutically acceptable auxiliary materials are added into the dressing, and then the dressing is placed on a carrier to form the patch.
In preparing the patch, those skilled in the art can select suitable adjuvants in the prepared dressing according to the general knowledge in pharmacy, which may include aromatics (such as perfume, essence, etc.), mucilage (specifically, sodium alginate, acacia, gelatin, methylcellulose, sodium carboxymethylcellulose, etc.), clarifiers (specifically, chitosan, gelatin, etc.), preservatives (specifically, benzoic acid and its salt, sorbic acid and its salt, nipagin series, etc.), disintegrators (specifically, low-substituted hydroxypropylcellulose, crospovidone, sodium starch glycolate, croscarmellose sodium, starch, etc.), binders (specifically, hydroxypropylcellulose, hypromellose, povidone, copovidone, pregelatinized starch, etc.), lubricants (specifically, stearic acid, magnesium stearate, sodium fumarylstearate, etc.), wetting agents (specifically, polyoxyethylene sorbitan fatty acid ester, poloxamer, polyoxyethylene castor oil derivative, etc.), suspending agent (specifically, hypromellose, hydroxypropyl cellulose, povidone, copovidone, sodium carboxymethylcellulose, methylcellulose, etc.), stabilizer (specifically, citric acid, fumaric acid, succinic acid, etc.), filler (specifically, starch, sucrose, lactose, microcrystalline cellulose, etc.), binder (specifically, cellulose derivative, alginate, gelatin, polyvinylpyrrolidone, etc.), etc.
Further optionally, the carrier comprises at least one of a non-woven fabric, gauze, adhesive tape, plaster, or medical rubber.
The invention also provides application of the traditional Chinese medicine patch for moistening lung and relieving cough in preparation of a medicine, wherein the medicine is used for preventing and/or treating infantile or adult diseases, preferably, the diseases are selected from cough, expectoration, pharyngalgia or pharynx itch.
The medicinal materials used in the invention have the following effects:
the folium Mori is dry leaf of Morus alba L of Moraceae, and has bitter, sweet and cold properties, and has effects of dispelling pathogenic wind and heat, clearing lung-heat, moistening dryness, calming liver, improving eyesight, cooling blood, and stopping bleeding. Is mainly used for treating wind-heat type common cold, lung heat dry cough, dizziness, headache, conjunctival congestion and dim flower.
The radix Glehniae is dried rhizome of Eucheuma Gelatinosum of Umbelliferae, and has sweet, slightly bitter and cold properties, and enters lung and spleen channels. Has the functions of nourishing yin, clearing away lung-heat, eliminating phlegm and relieving cough. It is mainly used for treating dry cough due to lung heat, cough due to overstrain, phlegm and blood, and thirst due to body fluid consumption due to fever.
The Bulbus Fritillariae Thunbergii is bulb of Bulbus Fritillariae Thunbergii of Liliaceae, and has bitter and cold taste, and has effects of clearing heat, eliminating phlegm, resolving hard mass and removing toxic substance. It is mainly used for treating cough due to wind-heat evil, lung abscess, sore throat, scrofula, sore, ulcer and pyogenic infections.
The vinegar fructus Schisandrae chinensis is dried mature fruit of fructus Schisandrae chinensis of Magnoliaceae, has sour, sweet and warm taste, and has effects of astringing, arresting discharge, invigorating qi, promoting fluid production, invigorating kidney, and calming heart. It is mainly used for treating chronic cough, asthma, nocturnal emission, enuresis, frequent micturition, chronic diarrhea, spontaneous perspiration, night sweat, thirst due to body fluid consumption, short breath, weak pulse, internal heat, diabetes, palpitation, and insomnia.
The gallnut is prepared by stabbing young leaves or leafstalks of a plant 'rhus chinensis' of the family Hovenia of the family Anacardiaceae and other plants of the same genus to generate a sac-like poly-biological insect gall, and baking and drying the gall, wherein the gall is sour, astringent and cold in taste, enters lung, kidney and large intestine channels, and has the functions of astringing lung and reducing internal heat, astringing intestine, securing essence, arresting sweating and stopping bleeding. It is mainly used for treating chronic cough due to lung deficiency, chronic diarrhea and dysentery, spontaneous perspiration and night sweat, diabetes, hemafecia, hemorrhoidal bleeding, traumatic hemorrhage, carbuncle, swelling, sore, and skin ulcer.
The inventor of the invention carries out deep research on the etiology and pathogenesis of the infantile cough on the basis of years of clinical experience, and considers that the main exogenous cause of the cough is wind evil and dryness pathogen, the main endogenous cause is lung and spleen weakness, the lesion is in the lung and often relates to the spleen, and the basic pathogenesis is the failure of the lung to disperse and descend. Exogenous pathogenic factors entering from the mouth, nose or skin and hair firstly invade the lung, leading to failure of the lung to disperse and descend, impairment of qi movement and adverse ascending of lung qi, and causing cough due to exogenous pathogenic factors. The infantile spleen often is deficient, the spleen deficiency produces phlegm, which is stored in the lung, or the cough is not cured for a long time, and the consumption of healthy qi can turn into internal injury cough. The treatment principle drawn according to the pathogenesis of the disease is as follows: disperse exogenous pathogens, ventilate lung qi. The invention combines the traditional Chinese medicinal materials of mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut to prepare the patch for treating the cough caused by wind dryness and pathogenic qi invading the lung of children, and the formula thinking is as follows: the mulberry leaf is a monarch drug, and has the two purposes of externally dispersing wind evil and internally moistening lung and dryness. Radix glehniae is a ministerial drug, has the effect of moistening lung dryness and has the characteristic of preferring to moisten lung without dryness. Zhejiang fritillaria bulb, schisandra chinensis and gallnut are assistant and guide medicines, schisandra chinensis enters five internal organs, the basic taste is acid, the property is mainly collected, the traditional Chinese medicine is often used for treating cough and astringing lung qi, and the gallnut prevents the disease from generating changes. It should be noted that the formula is suitable for the early stage and the late stage of cough, and is not recommended to be used when the cough is profuse and yellow in middle stage. The traditional Chinese medicine patch disclosed by the invention combines and uses the mulberry leaves, the radix glehniae, the thunberg fritillary bulb, the vinegar-processed schisandra chinensis and the gallnut, fully exerts the drug effects of the components by spleen and lung by utilizing the monarch, minister, assistant and guide interaction relationship among the components, and achieves the effects of moistening lung and relieving cough.
The method for treating the infantile cough by adopting the traditional Chinese medicine patch provided by the invention comprises the following steps: the traditional Chinese medicine patch is pasted on the Danzhong acupoint and the Feishu acupoint for two hours every day, one treatment course is 7 days, and better curative effect can be obtained by continuously using four treatment courses.
Compared with the prior art, the traditional Chinese medicine patch has the beneficial effects that:
the traditional Chinese medicine patch has good curative effect on cough caused by wind dryness and pathogenic factors attacking the lung of the children, is easily accepted by infants and children by external application treatment in the form of the patch, is beneficial to medicine absorption, and has reasonable formula and no toxic or side effect.
Detailed Description
The present invention is further described in the following description of the specific embodiments, which is not intended to limit the invention, but various modifications and improvements can be made by those skilled in the art according to the basic idea of the invention, within the scope of the invention, as long as they do not depart from the basic idea of the invention.
Example 1
Taking 3 parts by weight of mulberry leaves, 3 parts by weight of radix glehniae, 3 parts by weight of thunberg fritillary bulb, 3 parts by weight of vinegar schisandra chinensis and 3 parts by weight of gallnut; cleaning the Chinese medicinal materials for later use; drying the inclined clean Chinese medicinal materials in a dryer at 50 deg.C for 30 min; pulverizing the dried Chinese medicinal materials respectively, sieving with 80 mesh sieve, and mixing to obtain medicinal powder. Adding appropriate amount of rice vinegar into the medicinal powder, concocting into paste to obtain dressing, and placing the dressing on medical gauze to obtain patch.
Wherein, the vinegar schisandra chinensis is purchased directly or prepared by schisandra chinensis according to the legal processing method of Chinese pharmacopoeia;
example 2
Obtaining raw material of vinegar schisandra fruit according to the method of example 1;
taking 1 part by weight of mulberry leaves, 3 parts by weight of radix glehniae, 3 parts by weight of thunberg fritillary bulb, 2 parts by weight of vinegar schisandra chinensis and 1 part by weight of gallnut; cleaning the Chinese medicinal materials for later use; drying the inclined clean Chinese medicinal materials in a dryer at 55 deg.C for 30 min; pulverizing the dried Chinese medicinal materials respectively, sieving with 50 mesh sieve, and mixing to obtain medicinal powder. Adding appropriate amount of rice vinegar into the medicinal powder, concocting into paste to obtain dressing, and placing the dressing on medical gauze to obtain patch.
Example 3
Obtaining raw material of vinegar schisandra fruit according to the method of example 1;
taking 1 part by weight of mulberry leaves, 2 parts by weight of radix glehniae, 1 part by weight of thunberg fritillary bulb, 1 part by weight of vinegar schisandra chinensis and 2 parts by weight of gallnut; cleaning the Chinese medicinal materials for later use; drying the inclined clean Chinese medicinal materials in a dryer at 60 deg.C for 40 min; pulverizing the dried Chinese medicinal materials respectively, sieving with 100 mesh sieve, and mixing to obtain medicinal powder. Adding appropriate amount of rice vinegar into the medicinal powder, concocting into paste to obtain dressing, and placing the dressing on medical gauze to obtain patch.
Example 4
Obtaining raw material of vinegar schisandra fruit according to the method of example 1;
taking 1 part by weight of mulberry leaves, 1 part by weight of radix glehniae, 2 parts by weight of thunberg fritillary bulb, 3 parts by weight of vinegar schisandra chinensis and 3 parts by weight of gallnut; cleaning the Chinese medicinal materials for later use; drying the inclined clean Chinese medicinal materials in a dryer at 52 deg.C for 32 min; pulverizing the dried Chinese medicinal materials respectively, sieving with 80 mesh sieve, and mixing to obtain medicinal powder. Adding appropriate amount of rice vinegar into the medicinal powder, concocting into paste to obtain dressing, and placing the dressing on adhesive plaster to obtain patch.
Example 5
Obtaining raw material of vinegar schisandra fruit according to the method of example 1;
taking 1 part by weight of mulberry leaves, 1 part by weight of radix glehniae, 1 part by weight of thunberg fritillary bulb, 1 part by weight of vinegar schisandra chinensis and 1 part by weight of gallnut; cleaning the Chinese medicinal materials for later use; drying the inclined clean Chinese medicinal materials in a dryer at 58 deg.C for 40 min; pulverizing the dried Chinese medicinal materials respectively, sieving with 50 mesh sieve, and mixing to obtain medicinal powder. Adding appropriate amount of rice vinegar into the medicinal powder, concocting into paste to obtain dressing, adding appropriate amount of gelatin into the dressing, stirring, and placing on medical gauze to obtain patch.
Example 6
Obtaining raw material of vinegar schisandra fruit according to the method of example 1;
taking 1 part by weight of mulberry leaves, 2 parts by weight of radix glehniae, 2 parts by weight of thunberg fritillary bulb, 2 parts by weight of vinegar schisandra chinensis and 2 parts by weight of gallnut; cleaning the Chinese medicinal materials for later use; drying the inclined clean Chinese medicinal materials in a dryer at 55 deg.C for 35 min; pulverizing the dried Chinese medicinal materials respectively, sieving with 80 mesh sieve, and mixing to obtain medicinal powder. Adding appropriate amount of rice vinegar into the medicinal powder, concocting into paste to obtain dressing, adding appropriate amount of sorbic acid into the dressing, stirring, and placing on medical gauze to obtain patch.
Test examples
The experimental example is a clinical study on the aspect of treating infantile cough by using the traditional Chinese medicine patch.
1. Clinical trial procedure
100 children patients in cough symptoms are randomly selected in Beijing Huimin traditional Chinese medicine medical science, and the clinical diagnosis bases of the children are cough, expectoration, pharyngalgia, pharynx itch and rhinorrhea. Two or more symptoms appear, lasting for one or more weeks without exceeding four weeks, and no improvement is seen. The average age of the children patients is 4 years and 10 months, and the proportion of male to female is 1: 1.
the children patients are classified into four different grades of mild, severe and severe according to the cough symptom degree of the children patients, and the specific classification standard is as shown in the table I:
table one: grading standard of disease symptoms of children patients
Figure BDA0002476111930000081
Figure BDA0002476111930000091
The diagnosis and treatment method comprises the following steps: the Chinese medicinal patch prepared in example 1 was applied to Danzhong and Feishu acupoints of affected infants once a day for two hours each time, seven days for one treatment period, and continuously observed for four weeks.
All children patients are observed and counted according to a unified scientific research design, and are researched in a self-front-back comparison mode. And (5) adopting a classification statistical method, and setting 10 classifications of improvement conditions of each symptom from weak to strong. The scores for different symptoms were set as follows: improvement of nasal symptoms: the symptoms are reduced with the same symptoms (0 min), the nasal discharge is basically stopped with slight improvement of ventilation (1-5 min), and the ventilation is obviously improved (6-10 min); pharyngeal discomfort condition: has no obvious change (0 min) and slightly reduces (1-5 min) the throat itch or basically has no feeling (6-10 min); improvement of cough: without any change (score 0) a slight decrease in cough frequency or duration (score 1-5) a significant decrease in cough frequency or duration (score 6-10);
the diagnosis and treatment conditions of the children patients at different levels after the medicine is taken are divided into invalid, effective and recovery, wherein the total score is 0, 1-15, 16-18 and 19-30, respectively. After four weeks of continuous post-medication, the post-medication diagnosis and treatment conditions of all children patients are as shown in table two:
TABLE II, clinical test results after drug administration for children patients
Number of cases before administration Number of cure cases Number of effective cases Effective number of cases Number of invalid cases
Light and slight 30 7 14 9 0
Is lighter 56 11 24 20 1
Heavy weight 8 2 4 1 1
Severe severity of disease 6 1 3 1 1
After four weeks of treatment, all children patients meet the curative effect standard above the effective curative effect, and no obvious adverse reaction is found in the treatment process.
2. Case analysis
Case one: the children patients are 4 years old and female, have more than two weeks of cough, have heavier cough sound and have pharynx itch and sore throat. After one week of application, the throat is not painful, the throat is slightly itchy, and the cough symptoms are relieved. The pharynx itch disappears after continuously applying for two weeks, and the cough is occasionally occurred. The symptoms completely disappeared after two weeks of continued application.
Case two: the children patients are 3 years old and male with gender, cough with symptoms of about one week, dry cough without phlegm, throat itching and no pain. After one week of the application treatment, the pharynx itch symptom disappears and the cough still exists. Cough symptoms disappeared after two weeks of continued treatment.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A traditional Chinese medicine patch for moistening lung and relieving cough is characterized by comprising the following traditional Chinese medicinal materials:
mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
2. The traditional Chinese medicine patch for moistening lung to arrest cough according to claim 1, wherein the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 1-3: 1-3: 1-3: 1-3 of mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
3. The traditional Chinese medicine patch for moistening lung to arrest cough according to claim 1, wherein the traditional Chinese medicine patch comprises the following components in a weight ratio of 1: 1: 1: 1: 1 mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
4. The traditional Chinese medicine patch for moistening lung to arrest cough according to claim 1, wherein the traditional Chinese medicine patch is prepared from the following raw materials in a weight ratio of 1: 1-3: 1-3: 1-3: 1-3 of mulberry leaf, coastal glehnia root, thunberg fritillary bulb, vinegar-processed Chinese magnoliavine fruit and gallnut.
5. A method for preparing a lung moistening and cough arresting traditional Chinese medicine patch according to any one of claims 1 to 4, characterized in that the preparation method comprises:
weighing mulberry leaves, radix glehniae, thunberg fritillary bulb, vinegar-processed schisandra chinensis and gallnut according to parts by weight, cleaning, drying, crushing and sieving the medicinal materials to obtain medicinal material powder; adding rice vinegar into the medicinal powder, blending into paste to obtain dressing, and placing the dressing on a carrier to obtain the patch.
6. The method for preparing a Chinese medicinal patch according to claim 5, wherein the drying temperature is 50-60 deg.C and the drying time is 30-40 min.
7. The method for preparing a Chinese medicinal patch according to claim 5, wherein the pulverized herbs are sieved with 50-100 mesh sieve.
8. The method for preparing a Chinese medicinal patch according to claim 5, wherein a pharmaceutically acceptable adjuvant is added to the dressing, and then the dressing is placed on a carrier to prepare the patch.
9. The patch of any one of claims 5-8 wherein said carrier comprises at least one of a non-woven fabric, gauze, adhesive, plaster, or medical rubber.
10. Use of a patch according to any one of claims 1-4 for the manufacture of a medicament for the prevention and/or treatment of a pediatric condition selected from cough, expectoration, sore throat or itching throat.
CN202010364491.3A 2020-04-30 2020-04-30 Traditional Chinese medicine patch for moistening lung to arrest cough and preparation method thereof Active CN111467426B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170062345A (en) * 2015-11-27 2017-06-07 랜기어 테크놀로지 컴퍼니 리미티드 Chinese medicine for cough treatment
CN108079109A (en) * 2017-12-29 2018-05-29 付少军 A kind of prescription for effecting a radical cure asthma and preparation method thereof
CN108498700A (en) * 2018-06-22 2018-09-07 山东药品食品职业学院 A kind of Chinese medicine composition and preparation method thereof for treating cough

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170062345A (en) * 2015-11-27 2017-06-07 랜기어 테크놀로지 컴퍼니 리미티드 Chinese medicine for cough treatment
CN108079109A (en) * 2017-12-29 2018-05-29 付少军 A kind of prescription for effecting a radical cure asthma and preparation method thereof
CN108498700A (en) * 2018-06-22 2018-09-07 山东药品食品职业学院 A kind of Chinese medicine composition and preparation method thereof for treating cough

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