CN111450226B - Honeyed pill for treating novel coronavirus pneumonia and preparation method thereof - Google Patents
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Abstract
A honeyed pill for the treatment of new coronavirus pneumonia and its preparation method, relate to the technical field of the medicine, the Chinese ephedra of the invention is lung-ventilating, cinnabar, radix et rhizoma Rhei detoxify and clear away heat, rhizoma Zingiberis warms the spleen and dispels the dampness, rhizoma Gastrodiae dispels the wind and subdues dampness, mung bean, radix usnea tea, licorice clear away heat and monitor the toxin of cinnabar, the realgar has effects of detoxifying and killing parasite, eliminating dampness and eliminating phlegm, antimalarial, all medicines are lung-ventilating, detoxify, dispel the dampness, clear away heat, the invention is close to the disease pathogenesis of new coronavirus pneumonia at present, start with from "lung-ventilating, detoxify, dispel the dampness, clear away heat", make honeyed pill for new coronary confirmation and suspected and convalescence patient after going out of hospital, compared with the traditional Chinese medicine decoction or Chinese patent medicine capsule, the honeyed pill has the advantages of convenient administration, acceleration of gastrointestinal absorption, the novel coronavirus pneumonia therapeutic instrument has the advantages of convenience in popularization and the like, can be effectively used for clinical treatment of the novel coronavirus pneumonia in time, adds a new means for prevention and control of epidemic situations, and is suitable for large-scale popularization and application.
Description
Technical Field
The invention relates to the technical field of medicines, and particularly relates to honeyed pills for treating novel coronavirus pneumonia and a preparation method thereof.
Background
Because the disease is a new infectious disease, the source, pathogenesis and the like of the disease are not clear at present, and specific antiviral drugs are lacked, thereby bringing great difficulty to clinical diagnosis and treatment and epidemic situation control.
Combines the epidemiological characteristics of Henan province from south to north, and simultaneously combines the main manifestations of low fever, hypodynamia, anorexia, nausea, fullness in chest and epigastrium and loose stool in the early disease stage of the existing patients; the tongue coating is thick and greasy no matter yellow and white; the development of the disease is mostly characterized by sudden body temperature rise after low fever lasts for several days, and the asthmatic suffocation suddenly enters a critical state; and the clinical characteristics of thermolabile property of the novel coronavirus and the like, the applicant considers that the pneumonia infected by the novel coronavirus belongs to the category of the traditional Chinese medicine plague. The etiology is "pathogenic dampness-toxicity", the basic pathogenesis is that dampness-toxicity closes the lung, and the ascending and descending are disordered, even the internal closure is lost. Therefore, the core of the pathogenesis of the pneumonia infected by the novel coronavirus is 'damp toxin'; belongs to the harmful category of dampness, heat, toxicity and deficiency; the disease location is lung and spleen; for treating "dispersing lung qi, removing toxicity, resolving dampness, clearing heat" etc.
Therefore, how to provide honeyed pills for treating the novel coronavirus pneumonia and a preparation method thereof become a long-term technical demand of the technical personnel in the field.
Disclosure of Invention
In order to overcome the defects in the background technology, the invention provides honeyed pills for treating novel coronavirus pneumonia and a preparation method thereof.
In order to achieve the above purpose, the invention adopts the following technical scheme:
the honeyed pill for treating the novel coronavirus pneumonia comprises the following components in parts by weight:
40-80 g of ephedra;
20-60 g of realgar;
40-80 g of dried ginger;
40-80 g of gastrodia elata;
40-80 g of mung beans;
20-60 g of raw liquorice;
80-120 g of rheum officinale;
40-80 g of usnea tea;
20-60 g of cinnabar.
The realgar is realgar which is honeyed pill for treating the novel coronavirus pneumonia.
The gastrodia elata is rhizoma gastrodiae.
The rhubarb is raw rhubarb, and the honeyed pill is used for treating the novel coronavirus pneumonia.
The cinnabar is bright cinnabar.
The honeyed pill for treating the novel coronavirus pneumonia is characterized in that the ephedra is preferably 60g, the realgar is preferably 40g, the dried ginger is preferably 60g, the gastrodia elata is preferably 60g, the mung bean is preferably 60g, the raw licorice is preferably 40g, the rheum officinale is preferably 100g, the usnea tea is preferably 60g, and the cinnabar is preferably 40 g.
A preparation method of honeyed pills for treating novel coronavirus pneumonia comprises the steps of firstly crushing ephedra, realgar, dried ginger, gastrodia elata, mung bean, raw liquorice, rheum officinale and usnea tea into fine powder, grinding cinnabar into fine powder with water, mixing the fine powder and the fine powder, and preparing the honeyed pills together.
According to the preparation method of the honeyed pill for treating the novel coronavirus pneumonia, the diameter of the honeyed pill is 8-10 mm.
The preparation method of the honeyed pill for treating the novel coronavirus pneumonia comprises the following steps of: 0.9 to 1.5.
According to the preparation method of the honeyed pill for treating the novel coronavirus pneumonia, the honey is refined honey.
By adopting the technical scheme, the invention has the following advantages:
the invention has the advantages of dispersing lung qi by ephedra, cinnabar, rhubarb, detoxifying and clearing heat, dried ginger, warming spleen and eliminating dampness, rhizoma gastrodiae, dispelling wind and eliminating dampness, mung bean, usnea tea and liquorice, clearing heat and controlling cinnabar toxin, realgar has the efficacies of detoxifying and killing parasite, drying dampness and eliminating phlegm and preventing malaria, all the medicines have the functions of dispersing lung qi, detoxifying, resolving dampness and clearing heat, are in accordance with the novel pneumonia pathogenesis of coronavirus infection, are used for the disease at present and achieve certain effect, the invention tightly links the current novel coronavirus pneumonia pathogenesis, starts from 'dispersing lung qi, detoxifying, resolving dampness and clearing heat', and prepares honeyed pills for the confirmed diagnosis and suspected and rehabilitation patients after discharge of new crowns, compared with the traditional Chinese medicinal decoction or Chinese medicinal capsules, the honeyed pills have the advantages of convenient administration, accelerated absorption of gastrointestinal tract, convenient popularization and the like, can add effective clinical treatment for the novel coronavirus pneumonia in time, provide new means for prevention and control of epidemic situation and the like, is suitable for wide popularization and application.
Detailed Description
The present invention will be explained in more detail by the following examples, which are not intended to limit the invention;
the honeyed pill for treating the novel coronavirus pneumonia comprises the following components in parts by weight:
40-80 g of ephedra; 20-60 g of realgar;
40-80 g of dried ginger; 40-80 g of gastrodia elata;
40-80 g of mung beans; 20-60 g of raw liquorice;
80-120 g of rheum officinale; 40-80 g of usnea tea;
20-60 g of cinnabar.
Wherein the realgar is realgar, the gastrodia elata is gastrodia elata, the rhubarb is raw rhubarb, and the cinnabar is bright cinnabar.
Furthermore, in the specific implementation of the invention, the ephedra herb is preferably 60g, the realgar is preferably 40g, the dried ginger is preferably 60g, the gastrodia elata is preferably 60g, the mung bean is preferably 60g, the raw licorice is preferably 40g, the rheum officinale is preferably 100g, the usnea tea is preferably 60g, and the cinnabar is preferably 40 g.
A preparation method of honeyed pills for treating novel coronavirus pneumonia comprises the steps of firstly crushing ephedra, realgar, dried ginger, gastrodia elata, mung bean, raw liquorice, rheum officinale and usnea tea into fine powder, grinding cinnabar into fine powder with water, mixing the fine powder and the fine powder, and preparing the honeyed pills together. In specific implementation, the ephedra herb, the realgar, the dried ginger, the gastrodia elata, the mung bean, the raw liquorice, the rhubarb and the usnea tea are superfine ground into fine powder by a grinding machine. The diameter of the finally prepared honeyed pill is 8-10 mm.
Further, the ratio of the fine powder to the honey in the preparation of the honeyed pills is 1: 0.9 to 1.5. Wherein the honey is refined honey.
The honey pill is a plastic solid pill prepared by using refined honey as an adhesive, and the honey has the effects of moistening lung for arresting cough, relaxing bowel, tonifying middle-jiao for relieving urgency, moistening dryness for removing toxin and the like, and can supplement main medicines to improve curative effect and the like; the honeyed pill is sweet, can correct the medicinal taste, is soft and plastic, and the prepared pill is round, smooth, soft and moist, can be randomly changed into small granules for taking and can be dissolved with water for drinking, so the honeyed pill is suitable for children to take; in addition, the honey has strong adhesive force after refining, can effectively adhere to the medicine, and the surface of the pill after being mixed with the medicine powder is not easy to harden, is slowly disintegrated and has lasting effect, so that the medicine property is convenient to preserve, the oxidative deterioration, loss and damage of the effective components of the medicine are avoided, the inherent odor characteristics of the traditional Chinese medicine are kept, and the like.
The honeyed pill related by the invention has the following preparation steps:
firstly, uniformly mixing the fine powder and the fine flour, and then putting the mixture into a disinfection basin for later use;
and secondly, blending honey, namely blending honey (such as 500g of medicinal powder and 450-750 g of honey) according to the weight ratio of 1: 0.9-1.5 of the medicinal powder to the honey.
Step three, honey refining: the honey is refined by boiling, and the purpose of refining honey is to remove impurities, destroy enzymes, kill bacteria, evaporate water and enhance viscosity. When honey is refined, the honey is boiled by strong fire, then is boiled by slow fire, a bowl of cold water is placed beside the honey, the color of the honey is observed, when the honey turns yellow, a bamboo chopstick is used for dipping a drop of the honey in the honey, then the bamboo chopstick is moved to the upper part of the bowl of cold water, the honey is dropped into the water, and if the honey does not disperse in the water and sinks to the bottom (namely, the honey drops to form beads), the honey is refined. (if the honey is not refined to the fire, pills cannot be made, certainly, if the honey is too over the fire, the fire is not good, so the fire is mastered to a certain extent. the refined honey is divided into three types, namely tender honey, medium honey and old honey, wherein the tender honey is prepared by heating and boiling raw honey until the temperature reaches 105-115 ℃, filtering and removing foam, the color change of the refined honey is not obvious, the water loss is small, the refined honey is slightly viscous, and is suitable for preparing pills containing more starch, mucus, saccharides, fat and other medicinal materials with high viscosity, the medium honey is prepared by heating and boiling raw honey for a long time or continuously heating the tender honey to 116-118 ℃, foams are light red and glossy, hands are twisted with viscosity, but cannot pull long white filaments, and is suitable for preparing pills containing partial viscous or partial fibers, the old honey is prepared by heating raw honey for a longer time or continuously heating the tender honey and the medium honey to 122 ℃, so that the water is fully evaporated, and bubbles are red brown, has luster, is very sticky when twisted by hands, can pull out white silk, and is suitable for preparing pills containing medicinal materials with poor viscosity such as large amount of fiber or minerals. The honeyed pill is mostly made of honey, about 800g of refined honey can be obtained from 1000g of honey, about 1200g of refined honey needs to be obtained from 1000g of Chinese medicinal powder. )
Step four, mixing and blending the medicines: pouring the boiled honey into the medicinal powder contained in the disinfection basin by using a spoon, simultaneously stirring the medicinal powder by using thick bamboo chopsticks, pouring the honey while mixing the medicinal powder just like adding water and kneading dough before making dumplings at ordinary times, and stopping adding the honey when the dry medicinal powder is basically not seen (the honey cannot be added too much, and pills are not easy to form if more honey is added). If the total amount of honey is not well controlled at the beginning, the medicine powder can be remedied according to the dryness and humidity of the medicine powder when the honey is prepared. After the preparation, the medicine and the honey are put into a disinfection basin to be kneaded into a dough like dough.
Step five, pill mixing: in order to prevent the medicinal mass from sticking hands or sticking a device, a small amount of glycerin, sesame oil or peanut oil and the like can be dripped into the palm during pill mixing, so that the medicinal composition is not easy to stick and can be smooth and bright.
Sixth step, packaging and storing: the prepared honeyed pill has round and smooth appearance, compact and moist surface, no visible fiber or other abnormal color points, and can be packaged with wax paper, cellophane, plastic bag or wax shell, and stored in dry place.
When the invention is used for treatment, only 1 pill needs to be taken, and 1 pill needs to be taken again for serious patients, and the invention has obvious effect, greatly reduces the medical cost, shortens the treatment course and saves social resources. In addition, the honeyed pill is prepared by starting from the prescription of 'dispersing lung qi, expelling pathogenic factors, detoxifying, resolving dampness and clearing heat' and is used for newly determined and suspected patients and patients recovered after discharge. The final purpose of the invention is to ensure that suspected patients are converted into confirmed patients as little as possible or not, the mild symptoms of the confirmed patients are converted into severe symptoms as little as possible, and the bodies of the discharged patients are recovered to be normal as soon as possible. Therefore, the clinical advantages of the traditional Chinese medicine honeyed pills in treating the novel coronavirus pneumonia are reflected, a new means and a new method are added for epidemic prevention and control, and finally a new mode and a peculiar mark of the traditional Chinese medicine in epidemic prevention and treatment are explored.
The invention can be used for treating patients with the confirmed coronavirus pneumonia. 20 patients are added with the honeyed pills prepared by the invention for oral administration on the basis of general treatment. The clinical curative effect and the drug safety are evaluated according to the set observation indexes before and after the drug is taken, so that the clinical curative effect of the invention is further researched and verified.
The specific treatment scheme is as follows:
the honeyed pill prepared by the invention is added on the basis of general treatment for oral administration: it is taken 1 time with 1 granule each time and a small amount of cold boiled water. When the medicine is taken, one pill for adults and one pill for children are taken after being mixed with cold water, and the patient can be cured after sweating, and the patient with serious symptoms is taken continuously. After taking the medicine, hot soup and hot substance should not be taken when the patient does not sweat, and after sweating, the patient should not take the medicine.
The curative effect is as follows:
(1) the body temperature returns to normal for more than 3 days.
(2) The respiratory symptoms are obviously improved.
(3) Pulmonary imaging showed significant absorption of the inflammation.
(4) Mild cases did not progress to severe cases, or were suspected to have not yet developed a definitive diagnosis.
(5) The hospitalization time is shortened.
(6) The cure rate is improved.
The honeyed pills prepared by the invention are completely taken by inpatients in the first subsidiary hospital of the university of science and technology in Henan, and no case is changed into severe cases. It is expected that all will be discharged after one week, and the first home in the province achieved a patient with a novel coronavirus-free pneumonia in the hospital.
By analyzing the clinical curative effect of honeyed pills on patients with the novel coronavirus pneumonia, suspected patients and patients discharged from hospital and evaluating the clinical safety of the patients, the medicament is expected to be popularized and used in clinic at last, and guarantee and support are provided for epidemic prevention and control work.
According to the development trend of the current novel coronavirus pneumonia epidemic situation, the outbreak period can be 7 to 14 days in the future, the prevention and control of the epidemic situation and the treatment of confirmed cases are not slow, and meanwhile, the outbreak season of the disease is still presumed to be 2-5 months according to the outbreak rule of respiratory infectious diseases, so that the novel coronavirus pneumonia early warning system has a wide clinical application prospect, has an important significance for the prevention and treatment of the novel coronavirus pneumonia, and can obtain good social benefits. The method brings great social benefits to the prevention and control work of the epidemic situation of the novel coronavirus infectious disease at present.
The present invention is not described in detail in the prior art.
The embodiments selected for the purpose of disclosing the invention, are presently considered to be suitable, it being understood, however, that the invention is intended to cover all variations and modifications of the embodiments which fall within the spirit and scope of the invention.
Claims (10)
1. A honeyed pill for treating novel coronavirus pneumonia is characterized in that: the honeyed pill comprises the following components in parts by weight:
40-80 g of ephedra;
20-60 g of realgar;
40-80 g of dried ginger;
40-80 g of gastrodia elata;
40-80 g of mung beans;
20-60 g of raw liquorice;
80-120 g of rheum officinale;
40-80 g of usnea tea;
20-60 g of cinnabar.
2. The honeyed pill for treating novel coronavirus pneumonia according to claim 1, which is characterized in that: the realgar is realgar.
3. The honeyed pill for treating novel coronavirus pneumonia according to claim 1, which is characterized in that: the rhizoma Gastrodiae is rhizoma Gastrodiae.
4. The honeyed pill for treating novel coronavirus pneumonia according to claim 1, which is characterized in that: the rhubarb is raw rhubarb.
5. The honeyed pill for treating novel coronavirus pneumonia according to claim 1, which is characterized in that: the Cinnabaris is bright Cinnabaris.
6. The honeyed pill for treating novel coronavirus pneumonia according to claim 1, which is characterized in that: the weight proportion of the ephedra is preferably 60g, the weight proportion of the realgar is preferably 40g, the weight proportion of the dried ginger is preferably 60g, the weight proportion of the gastrodia elata is preferably 60g, the weight proportion of the mung bean is preferably 60g, the weight proportion of the raw licorice is preferably 40g, the weight proportion of the rhubarb is preferably 100g, the weight proportion of the usnea tea is preferably 60g, and the weight proportion of the cinnabar is preferably 40 g.
7. The method for preparing honeyed pills for treating novel coronavirus pneumonia according to any one of claims 1-6, wherein the honeyed pills comprise: the preparation method comprises the steps of firstly, crushing ephedra, realgar, dried ginger, gastrodia elata, mung bean, raw liquorice, rhubarb and usnea tea into fine powder, grinding cinnabar into fine powder, mixing the fine powder and the fine powder uniformly, and preparing honeyed pills.
8. The method for preparing honeyed pills for treating novel coronavirus pneumonia according to claim 1, wherein the honeyed pills are prepared by the following steps: the diameter of the honeyed pill is 8-10 mm.
9. The method for preparing honeyed pills for treating novel coronavirus pneumonia according to claim 1, wherein the honeyed pills are prepared by the following steps: the ratio of the fine powder to the honey in the preparation of the honeyed pill is 1: 0.9 to 1.5.
10. The method for preparing honeyed pills for treating novel coronavirus pneumonia according to claim 9, wherein the honeyed pills are prepared by the following steps: the honey is refined honey.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1562301A (en) * | 2004-04-01 | 2005-01-12 | 殷其昌 | Chinese traditional medicine for treating atypical pneumonia |
| CN1660160A (en) * | 2004-02-26 | 2005-08-31 | 朱胜龙 | Combination of Chinese traditional medicine in use for treating atypical pneumonia etc communicable diseases |
| CN102526654A (en) * | 2011-10-21 | 2012-07-04 | 罗苓 | Pill for aversion to cold and adiapneustia |
-
2020
- 2020-02-20 CN CN202010103633.0A patent/CN111450226B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660160A (en) * | 2004-02-26 | 2005-08-31 | 朱胜龙 | Combination of Chinese traditional medicine in use for treating atypical pneumonia etc communicable diseases |
| CN1562301A (en) * | 2004-04-01 | 2005-01-12 | 殷其昌 | Chinese traditional medicine for treating atypical pneumonia |
| CN102526654A (en) * | 2011-10-21 | 2012-07-04 | 罗苓 | Pill for aversion to cold and adiapneustia |
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| CN111450226A (en) | 2020-07-28 |
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