CN111449178B - Feed additive suitable for meat ducks and preparation and use methods thereof - Google Patents
Feed additive suitable for meat ducks and preparation and use methods thereof Download PDFInfo
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
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- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K20/00—Accessory food factors for animal feeding-stuffs
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- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
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- A—HUMAN NECESSITIES
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- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/22—Compounds of alkali metals
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The application relates to a feed additive suitable for meat ducks and a preparation and use method thereof, belonging to the field of feed additives, and comprising the following raw materials, by weight, 5-8 parts of vitamin A, 30-50 parts of vitamin E, 100-150 parts of vitamin C, 150-200 parts of soybean isoflavone, 300-400 parts of glutathione, 30-50 parts of selenomethionine, 100-150 parts of tert-butyl p-diphenol (TBHQ), 200-400 parts of eggshell quality regulator and 150-250 parts of intestinal health regulator. The additive is designed according to the nutritional requirements of the meat ducks in the egg laying period, mainly considers the development and health care of reproductive organs, improves the egg quality, and effectively improves the fertility rate and the hatching rate. The healthy chick rate is obviously improved.
Description
Technical Field
The application belongs to the field of feed additives, and relates to a feed additive for improving the healthy chick rate in the egg laying period of meat ducks and a preparation and application method thereof.
Background
The disclosure of this background section is only intended to increase the understanding of the general background of the application and is not necessarily to be construed as an admission or any form of suggestion that this information forms the prior art already known to those of ordinary skill in the art.
The healthy chick rate is one of the key indexes for measuring the quality of the breeding poultry and the hatching eggs. Factors influencing the health rate mainly comprise breeding poultry feeding management, fertilization management, nutrition management, hatching egg management and hatching management, and quantitative indexes comprise fertilization rate and hatching rate. Under the background of standardized industrial hatching, the quality of hatching eggs becomes an important determinant of the healthy chick rate, so that the nutrition and feeding technology of the breeding ducks related to the quality of the breeding ducks are particularly critical to the healthy chick rate.
Egg quality is measured primarily by eggshell thickness, egg shape index, egg weight, hash units, eggshell strength, and antioxidant index. Healthy breeding ducks can realize high-yield and high-quality production through nutrition and fine management of proportion science, and researches and applications of amino acid, metabolic energy, trace elements, vitamins and the like exist, and the related technology can realize the adjustment of egg weight, eggshell quality and the like, but the inventor discovers that: nutritional schemes for the antioxidant level of hatching eggs have not been reported, limiting the improvement of healthy chick rates.
Disclosure of Invention
In order to overcome the problems, the application aims to improve the fertility rate of the breeding ducks in the feeding process by adding functional nutritional additives into the breeding ducks, so as to improve the hatchability and the healthy young ducks, and according to the special physiological characteristics of the breeding ducks in the egg-laying peak period, the physiological needs and the nutritional needs of the breeding ducks in the peak period are taken as main nutritional index design basis; the method aims at promoting the development and health care of reproductive organs (oviduct and ovary) of the meat ducks, and improves the fertility, disease resistance and body health state of the meat ducks by adding key nutrients, so as to improve the hatching rate and the healthy young ducks of the egg ducks.
In order to achieve the technical purpose, the application adopts the following technical scheme:
the first aspect of the application provides a feed additive suitable for meat ducks, which comprises, by weight, 5-8 parts of vitamin A, 30-50 parts of vitamin E, 100-150 parts of vitamin C, 150-200 parts of soybean isoflavone, 300-400 parts of glutathione, 30-40 parts of selenomethionine, 100-150 parts of tert-butyl p-diphenol (TBHQ), 200-400 parts of eggshell quality regulator and 150-250 parts of intestinal health regulator.
The feed disclosed by the application is scientific in compatibility, scientific in material proportion, simple to manufacture, balanced in nutrition of the product and reasonable in formula, and can enhance the antioxidation function, improve the egg quality, obviously improve the antioxidation level of the hatching eggs and realize the improvement of the healthy young percentage by the synergistic effect of the vitamin C and the tertiary butyl p-diphenol.
In a second aspect of the application, there is provided a method of formulating a feed additive suitable for meat ducks comprising:
preparing eggshell quality regulator;
preparing an intestinal health regulator;
mixing vitamin A, vitamin E, vitamin C, soybean isoflavone, glutathione, selenomethionine, tert-butyl p-diphenol, eggshell quality regulator and intestinal health regulator.
The preparation method is simple, the raw materials can be stored separately, and the preparation is convenient and quick in use.
In a third aspect, the application provides a method for using a feed additive suitable for meat ducks, comprising:
the feed additive is added into the basic ration of the meat ducks, and the addition amount is 0.1-0.2% of the total weight of the basic ration.
The additive is designed according to the nutritional requirements of the meat ducks in the egg laying period, mainly considers the development and health care of reproductive organs, improves the egg quality, and effectively improves the fertility rate and the hatching rate. The healthy chick rate is obviously improved.
The application has the beneficial effects that:
(1) The additive is designed according to the nutritional requirements of the meat ducks in the egg laying period, mainly considers the development and health care of reproductive organs, improves the egg quality, and effectively improves the fertility rate and the hatching rate. The healthy chick rate is obviously improved.
(2) The feed disclosed by the application is scientific in compatibility, scientific in material proportion, simple to manufacture, balanced in nutrition of the product and reasonable in formula, and can be used for feeding the breeding ducks to enhance the antioxidation function, improve the egg quality, remarkably improve the antioxidation level of the hatching eggs and realize the improvement of the healthy young ducks.
(3) The application has simple formula, convenient operation and strong practicability.
Detailed Description
It should be noted that the following detailed description is illustrative and is intended to provide further explanation of the application. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.
As described in the background art, there is a need for an improvement in the antioxidant level of hatching eggs. Therefore, the application provides a feed additive for improving the healthy chick rate, which is suitable for the egg laying period of meat ducks and consists of the following components in parts by weight: 5-8 parts of vitamin A (50 ten thousand units/gram), 30-50 parts of vitamin E (50%), 100-150 parts of vitamin C, 150-200 parts of soybean isoflavone, 300-400 parts of glutathione, 30-50 parts of selenomethionine, 100-150 parts of tert-butyl p-diphenol (TBHQ), 200-400 parts of eggshell quality regulator and 150-250 parts of intestinal health regulator.
In the present application, the vitamin E (50%) means: the vitamin E content was 50%.
The eggshell quality regulator is prepared from the following raw materials in parts by weight: 20-30 parts of zinc methionine, 30-50 parts of manganese methionine, 30-50 parts of iron porphyrin, 8-10 parts of copper methionine and 50-100 parts of phytase. Glutathione is an active tripeptide formed by condensing glutamic acid, cysteine and glycine. The improved saccharomycete is used in fermenting preparation to produce glutathione in industrial scale. In the field of animal health care, glutathione is used as a novel efficient and safe feed additive, and has the functions of enhancing immunity, saving feed, promoting growth and improving meat quality.
The selenomethionine is 12500mg/kg, selenium is more than or equal to 5000mg/kg, and 40g of selenomethionine is recommended to be added into each ton of batch. Selenomethionine is used as an animal feed additive to provide a greater abundance of nutritional ingredients, as well as desirable trace element compounds.
The intestinal health regulator is prepared from the following raw materials in parts by weight: 20-30 parts of a compound enzyme preparation, 5-10 parts of enterococcus faecalis, 10-20 parts of bacillus subtilis, 15-25 parts of xylo-oligosaccharide, 10-20 parts of benzoic acid and 30-40 parts of anhydrous sodium sulfate. The intestinal health regulator can prevent heatstroke, relieve summer-heat, balance intestinal flora, improve disease resistance and anti-stress capability, secrete various digestive enzymes and B vitamins, and improve the digestibility of the feed.
The complex enzyme preparation consists of the following components in parts by weight: 10-20 parts of protease, 10-20 parts of lipase and 10-20 parts of xylanase, wherein the activity units of the protease, the lipase and the xylanase are respectively 1-2 ten thousand U/g, 0.5-1 ten thousand U/g and 0.5-1 ten thousand U/g. The use of the compound enzyme preparation can improve the content of intestinal phytase, stimulate the development of phytase and improve the absorption and utilization rate of the phytase in the feed by the laying hens.
The application will now be described in further detail with reference to the following specific examples, which should be construed as illustrative rather than limiting.
Example 1:
a feed additive for improving the healthy young chicken rate in the egg laying period of meat ducks is prepared from the following raw materials, by weight, 6 parts of vitamin A (50 ten thousand units/g), 40 parts of vitamin E (50%), 125 parts of vitamin C, 175 parts of soybean isoflavone, 350 parts of glutathione, 40 parts of selenomethionine, 125 parts of tert-butyl p-diphenol (TBHQ), 300 parts of eggshell quality regulator and 200 parts of intestinal health regulator.
The eggshell quality regulator is prepared from the following raw materials in parts by weight: 25 parts of zinc methionine, 40 parts of manganese methionine, 40 parts of iron porphyrin, 9 parts of copper methionine and 75 parts of phytase (the activity units are respectively 1.5 ten thousand U/g).
The selenomethionine is 12500mg/kg, and the selenium content is more than or equal to 5000mg/kg.
The intestinal health regulator is prepared from the following raw materials in parts by weight: 25 parts of a complex enzyme preparation, 7.5 parts of enterococcus faecalis, 15 parts of bacillus subtilis, 20 parts of xylooligosaccharide, 15 parts of benzoic acid and 35 parts of anhydrous sodium sulphate. Wherein the viable count of enterococcus faecalis and bacillus subtilis is 100 hundred million CFU/g and 300 hundred million CFU/g respectively.
The complex enzyme preparation consists of the following components in parts by weight: 15 parts of protease, 15 parts of lipase and 15 parts of xylanase, wherein the activity units of the protease, the lipase and the xylanase are respectively 1.5 ten thousand U/g, 0.8 ten thousand U/g and 0.7 ten thousand U/g.
Example 2:
a feed additive for improving the healthy young duck rate in the egg laying period of meat ducks is prepared from (by weight parts) vitamin A (50W/g) 5, vitamin E (50%) 30, vitamin C100, soybean isoflavone 150, glutathione 300, selenomethionine 30, tert-butyl p-diphenol (TBHQ) 100, eggshell quality regulator 200 and intestinal health regulator 150.
The eggshell quality regulator is prepared from the following raw materials in parts by weight: 20 parts of zinc methionine, 30 parts of manganese methionine, 30 parts of iron porphyrin, 8 parts of copper methionine and 50 parts of phytase (the activity units are respectively 1.5 ten thousand U/g).
The selenomethionine is 12500mg/kg, selenium is more than or equal to 5000mg/kg, and 40g of selenomethionine is recommended to be added into each ton of batch.
The intestinal health regulator is prepared from the following raw materials in parts by weight: 20-30 parts of a compound enzyme preparation, 5 parts of enterococcus faecalis, 10 parts of bacillus subtilis, 15 parts of xylooligosaccharide, 10 parts of benzoic acid and 30 parts of anhydrous sodium sulfate. Wherein the viable count of enterococcus faecalis and bacillus subtilis is 100 hundred million CFU/g and 300 hundred million CFU/g respectively.
The complex enzyme preparation consists of the following components in parts by weight: 10 parts of protease, 10 parts of lipase and 10 parts of xylanase, wherein the protease, the lipase and the xylanase have the activity units of 1 ten thousand U/g, 0.5 ten thousand U/g and 0.5 ten thousand U/g respectively.
Example 3:
a feed additive for improving the healthy young chicken rate in the egg laying period of meat ducks is prepared from the following raw materials, by weight, 8 parts of vitamin A (50 ten thousand units/g), 50 parts of vitamin E (50%), 150 parts of vitamin C, 200 parts of soybean isoflavone, 400 parts of glutathione, 50 parts of selenomethionine, 150 parts of tert-butyl p-diphenol (TBHQ), 400 parts of eggshell quality regulator and 250 parts of intestinal health regulator.
The eggshell quality regulator is prepared from the following raw materials in parts by weight: 30 parts of zinc methionine, 50 parts of manganese methionine, 50 parts of iron porphyrin, 10 parts of copper methionine and 100 parts of phytase (the activity units are respectively 1.5 ten thousand U/g).
The selenomethionine is 12500mg/kg, selenium is more than or equal to 5000mg/kg, and 40g of selenomethionine is recommended to be added into each ton of batch.
The intestinal health regulator is prepared from the following raw materials in parts by weight: 30 parts of a complex enzyme preparation, 10 parts of enterococcus faecalis, 20 parts of bacillus subtilis, 25 parts of xylooligosaccharide, 20 parts of benzoic acid and 40 parts of anhydrous sodium sulphate. Wherein the viable count of enterococcus faecalis and bacillus subtilis is 100 hundred million CFU/g and 300 hundred million CFU/g respectively.
The complex enzyme preparation consists of the following components in parts by weight: 20 parts of protease, 20 parts of lipase and 20 parts of xylanase, wherein the activity units of the protease, the lipase and the xylanase are respectively 2 ten thousand U/g, 1 ten thousand U/g and 1 ten thousand U/g.
Comparative example 1
A feed additive for improving the healthy young duck rate in the egg laying period of meat ducks is prepared from (by weight parts) vitamin A (50 ten thousand units/g) 6, vitamin E (50%) 40, vitamin C250, soybean isoflavone 175, glutathione 350, selenomethionine 40, eggshell quality regulator 300 and intestinal health regulator 200.
The eggshell quality regulator is prepared from the following raw materials in parts by weight: 25 parts of zinc methionine, 40 parts of manganese methionine, 40 parts of iron porphyrin, 9 parts of copper methionine and 75 parts of phytase (the activity units are respectively 1.5 ten thousand U/g).
The selenomethionine is 12500mg/kg, and the selenium content is more than or equal to 5000mg/kg.
The intestinal health regulator is prepared from the following raw materials in parts by weight: 25 parts of a complex enzyme preparation, 7.5 parts of enterococcus faecalis, 15 parts of bacillus subtilis, 20 parts of xylooligosaccharide, 15 parts of benzoic acid and 35 parts of anhydrous sodium sulphate. Wherein the viable count of enterococcus faecalis and bacillus subtilis is 100 hundred million CFU/g and 300 hundred million CFU/g respectively.
The complex enzyme preparation consists of the following components in parts by weight: 15 parts of protease, 15 parts of lipase and 15 parts of xylanase, wherein the activity units of the protease, the lipase and the xylanase are respectively 1.5 ten thousand U/g, 0.8 ten thousand U/g and 0.7 ten thousand U/g.
Comparative example 2
A feed additive for improving the healthy chick rate in the egg laying period of meat ducks is prepared from the following raw materials, by weight, 6 parts of vitamin A (50 ten thousand units/g), 40 parts of vitamin E (50%), 175 parts of soybean isoflavone, 350 parts of glutathione, 40 parts of selenomethionine, 250 parts of tert-butyl p-diphenol (TBHQ), 300 parts of eggshell quality regulator and 200 parts of intestinal health regulator.
The eggshell quality regulator is prepared from the following raw materials in parts by weight: 25 parts of zinc methionine, 40 parts of manganese methionine, 40 parts of iron porphyrin, 9 parts of copper methionine and 75 parts of phytase (the activity units are respectively 1.5 ten thousand U/g).
The selenomethionine is 12500mg/kg, and the selenium content is more than or equal to 5000mg/kg.
The intestinal health regulator is prepared from the following raw materials in parts by weight: 25 parts of a complex enzyme preparation, 7.5 parts of enterococcus faecalis, 15 parts of bacillus subtilis, 20 parts of xylooligosaccharide, 15 parts of benzoic acid and 35 parts of anhydrous sodium sulphate. Wherein the viable count of enterococcus faecalis and bacillus subtilis is 100 hundred million CFU/g and 300 hundred million CFU/g respectively.
The complex enzyme preparation consists of the following components in parts by weight: 15 parts of protease, 15 parts of lipase and 15 parts of xylanase, wherein the activity units of the protease, the lipase and the xylanase are respectively 1.5 ten thousand U/g, 0.8 ten thousand U/g and 0.7 ten thousand U/g.
Feeding test:
feeding tests were carried out in a layer farm of a subordinate farmer of a company, and 3000 breeding ducks for cherry valley meat at 30 weeks of age were randomly divided into 3 groups (additives were added according to the formulas of example 1, comparative example 1 and comparative example 2 respectively), 4 replicates of each group, and 250 replicates of each group (200 female ducks and 50 male ducks). The daily ration formula comprises 60 parts of corn, 23 parts of bean pulp, 4 parts of bran, 8 parts of stone powder and 5 parts of premix, the dosage of the additive is 0.1065% of the total weight of the ingredients, and the average daily feed intake of each duck is generally controlled to be 225-230 g. The feeding period is 30-48 weeks. The test results are shown in tables 1 and 2:
TABLE 1 Effect of additives on egg quality
Group of | Example 1 | Comparative example 1 | Comparative example 2 |
Yolk color | 8.84 | 8.79 | 8.56 |
Eggshell thickness/mm | 0.49 | 0.49 | 0.46 |
Average egg weight (g) | 92.39 | 91.82 | 91.69 |
TABLE 2 Effect of additives on egg laying performance of meat ducks
From the indexes of the egg laying performance and the egg quality shown in tables 1 and 2, after the additive of the embodiment 1 of the application is fed, the cherry valley meat breeding ducks can obtain better egg laying performance and egg quality during egg laying, and the hatching rate and the healthy chick rate are improved.
Finally, it should be noted that the above-mentioned embodiments are only preferred embodiments of the present application, and the present application is not limited to the above-mentioned embodiments, but may be modified or substituted for some of them by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application. While the foregoing description of the embodiments of the present application has been presented in conjunction with the drawings, it should be understood that it is not intended to limit the scope of the application, but rather, it is intended to cover all modifications or variations within the scope of the application as defined by the claims of the present application.
Claims (6)
1. The feed additive for the meat ducks is characterized by comprising, by weight, 5-8 parts of vitamin A, 30-50 parts of vitamin E, 100-150 parts of vitamin C, 150-200 parts of soybean isoflavone, 300-400 parts of glutathione, 30-40 parts of selenomethionine, 100-150 parts of tert-butyl p-diphenol, 200-400 parts of eggshell quality regulator and 150-250 parts of intestinal health regulator;
the intestinal health regulator is prepared from the following raw materials in parts by weight: 20-30 parts of a compound enzyme preparation, 5-10 parts of enterococcus faecalis, 10-20 parts of bacillus subtilis, 15-25 parts of xylooligosaccharide, 10-20 parts of benzoic acid and 30-40 parts of anhydrous sodium sulfate;
the eggshell quality regulator consists of the following raw materials in parts by weight: 20-30 parts of zinc methionine, 30-50 parts of manganese methionine, 30-50 parts of iron porphyrin, 8-10 parts of copper methionine and 50-100 parts of phytase;
the complex enzyme preparation consists of the following components in parts by weight: 10-20 parts of protease, 10-20 parts of lipase and 10-20 parts of xylanase;
the protease, the lipase and the xylanase have the activity units of 1-2 ten thousand U/g, 0.5-1 ten thousand U/g and 0.5-1 ten thousand U/g respectively;
the meat-type breeding ducks are cherry valley-type breeding ducks;
the using method of the feed additive for the meat ducks comprises the step of adding the feed additive into the basic ration of the meat ducks, wherein the addition amount of the feed additive is 0.1% of the total weight of the basic ration.
2. The feed additive for meat ducks according to claim 1, which comprises, by weight, 5-6 parts of vitamin A, 30-40 parts of vitamin E, 100-125 parts of vitamin C, 150-175 parts of soybean isoflavone, 300-350 parts of glutathione, 30-35 parts of selenomethionine, 100-125 parts of tert-butyl p-diphenol, 200-300 parts of eggshell quality regulator and 150-200 parts of intestinal health regulator.
3. The feed additive for meat ducks according to claim 1, which is characterized by comprising, by weight, 6-8 parts of vitamin A, 40-50 parts of vitamin E, 125-150 parts of vitamin C, 175-200 parts of soybean isoflavone, 350-400 parts of glutathione, 35-40 parts of selenomethionine, 125-150 parts of tert-butyl p-diphenol, 300-400 parts of eggshell quality regulator and 200-250 parts of intestinal health regulator.
4. The feed additive for meat ducks according to claim 1, wherein the eggshell quality regulator comprises the following raw materials in parts by weight: 20-25 parts of zinc methionine, 30-40 parts of manganese methionine, 30-40 parts of iron porphyrin, 8-9 parts of copper methionine and 50-75 parts of phytase.
5. The feed additive for meat ducks according to claim 1, wherein the eggshell quality regulator comprises the following raw materials in parts by weight: 25-30 parts of zinc methionine, 40-50 parts of manganese methionine, 40-50 parts of iron porphyrin, 9-10 parts of copper methionine and 75-100 parts of phytase.
6. A method of preparing a feed additive for meat ducks as defined in claim 1, comprising:
preparing eggshell quality regulator;
preparing an intestinal health regulator;
mixing vitamin A, vitamin E, vitamin C, soybean isoflavone, glutathione, selenomethionine, tert-butyl p-diphenol, eggshell quality regulator and intestinal health regulator.
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