CN111408058A - 一种多功能综合性诊疗仪 - Google Patents
一种多功能综合性诊疗仪 Download PDFInfo
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Abstract
本发明公开了一种多功能综合性诊疗仪，包括患者功能状态快速诊断系统、扫描仪、诊疗床/诊疗椅、激光治疗系统、太赫兹治疗子系统、红外治疗子系统、水激光治疗子系统，可实现自动控制、合理诊疗，扫描仪可任意调节照射部位，精确控制，并将结果显示在屏幕上，方便制定最佳治疗方案。治疗系统采用太赫兹振冲按摩、激光振动推拿、磁激光、磁喷嘴红外调制以及固定脉冲、氦氖激光模块联合。新一代太赫兹、红外、激光融合医疗诊断和治疗系统，在实践中利用物理治疗及反射疗法，实现太赫兹磁疗、红外热疗、激光疗法以及水激光活化疗法，在生命健康诊断与治疗领域具有广阔前景。
Description
技术领域
本发明涉及太赫兹、红外、激光技术以及医疗诊断和治疗技术领域，尤其是涉及一种多功能综合性诊疗仪。
背景技术
太赫兹波的频率在0.1THz到10THz范围，波长大概在0.03到3mm范围，介于微波与红外之间，曾被统称为远红外射线。
太赫兹波有着意想不到的生物效应，例如影响细胞生长、基因表达等。太赫兹波有一定程度的生物穿透性，在医学领域可以对人体深处脏器的疾病带来疗效。
生物大分子相互作用是重大生命现象与病变产生的关键动因，而太赫兹光子能量覆盖了生物大分子空间构象的能级范围。太赫兹频段包含了其他电磁波段无法探测到的直接代表生物大分子功能的空间构象等重要信息。因此，可以发展一种利用太赫兹扫描和干预生物大分子相互作用过程的新理论和新技术，为当前重大疾病诊断、有效干预提供先进的技术手段。
红外线是波长介于微波与可见光之间的电磁波，波长在1mm到760nm之间，比红光长的非可见光。
红外线可以改善血液循环，增加细胞的吞噬功能，消除肿胀，促进炎症消散，治疗慢性炎症。
现有市场上出现了很多的医疗设备，其中红外线治疗仪器具有很好的缓解、治疗人体各病灶的作用，红外线治疗仪器能够产生红外线，会引起人体细胞的原子和分子的共振，通过共鸣吸收，分子之间摩擦生热并形成热反应，处使皮下深层温度上升，并使微血管扩张，加速血液循环达到活化组织细胞、防止老化、强化免疫系统等目的。
远红外线是一种对人体有益的光，是生命之光。远红外线10大功效：改善血液循环、改善关节疼痛、调节自律神经、改善微循环系统、护肤美容、激活生物分子活性、增强新陈代谢、提高免疫功能、消炎作用以及镇痛作用。
激光治疗可以用于破坏肿瘤或癌前期的生长，激光常用于浅表性癌症的治疗，如基底细胞皮肤癌以及一些癌症的早期阶段，如宫颈癌、阴道癌和非小细胞肺癌。
激光治疗也可以用于缓解癌症的某些症状，如出血或阻塞，比如激光治疗可以用于收缩或破坏阻塞患者气管或食管的肿瘤，也可以用于切除结肠息肉或阻塞结肠或胃的肿瘤。
传统的医疗设备中，治疗仪器结构和功能较为单一，治疗效果不明显。
发明内容
有鉴于此，有必要提供一种新一代太赫兹、红外、激光融合医疗诊断和治疗系统，解决医疗领域难题，涉及神经学、心脏病学、胃肠病学、创伤学、整形外科、手术、皮肤病学、牙科、泌尿外科和肾脏学、妇科、耳鼻喉科学和运动医学等。
为了实现本发明的上述目的，特采用以下技术方案：
一种多功能综合性诊疗仪，包括患者功能状态快速诊断系统、扫描仪、诊疗床/诊疗椅、激光治疗系统、太赫兹治疗子系统、红外治疗子系统、水激光治疗子系统。
所述诊疗仪核心系统管理患者数据库，根据所述患者功能状态快速诊断系统的扫描报告，制定最佳治疗方案，提交给所述治疗系统操作执行。
所述患者功能状态快速诊断系统通过所述扫描仪获取患者心率变异性的功能分析、功能状态电击穿诊断、测量和分析大脑超循环活动情况和呼吸频率漂移分析。
所述扫描仪结合或选择性采用氦氖和/或红外激光进行身体多区域扫描，扫描频率高达 100-150Hz，最大定位区域(200*100sm)，可自动从一个区域过渡到另一个区域进行大批量快速扫描，且智能化计算扫描照射剂量。
所述太赫兹治疗子系统采用太赫兹振冲按摩、激光振动推拿、磁激光模块，实现太赫兹磁疗。
所述红外治疗子系统采用磁喷嘴红外调制模块和磁喷嘴红外固定脉冲模块，实现红外热疗。
所述激光治疗系统还采用氦氖激光模块，实现激光疗法。
所述水激光治疗子系统配备水力喷头、妇科喷嘴和口腔科喷嘴，实现水激光活化疗法。
所述诊疗床/椅加载恒定磁场，与红外热疗、激光照射联合作用。
所述诊疗仪还设置有供电装置和控制开关。
所述各治疗子系统采用高联合策略以最佳模式进行组织，以太赫兹磁疗(磁疗)、红外热疗(热疗)、激光疗法(光疗)为主，辅以水激光活化疗法(水疗)，多功能综合性技术融合实现医疗诊断和治疗。
本发明多功能综合性诊疗仪的技术优势：多方法、多途径实现医学治疗效果，有效治疗和预防100多种病症，内置病患综合诊断功能系统，可以同时相互独立地为7例患者提供治疗。
附图说明
图1是根据本公开的一种示例性实施例的多功能综合性诊疗仪的组成示意图。
具体实施方式
为使本发明的上述目的、特征和优点能够更加明显易懂，下面结合附图并通过具体的实施方式对本发明的多功能综合性诊疗仪做更加详细的描述，但本发明的保护范围并不仅限于此。
如图所示，本发明一种多功能综合性诊疗仪，包括患者功能状态快速诊断系统2、扫描仪3、诊疗床/诊疗椅4、激光治疗系统5、太赫兹治疗子系统6、红外治疗子系统7、水激光治疗子系统8。
所述诊疗仪核心系统1管理患者数据库11，根据所述患者功能状态快速诊断系统2的扫描报告，制定最佳治疗方案12，提交给所述治疗系统5操作执行。
系统核心软件提供所有系统资源的控制、医疗程序规划和实现的决策信息支持；管理患者数据库；编写个人疗程，选择最佳的治疗方法；管理已知的数据库和再次设计的治疗技术；方便快捷的访问中心所有资源，选择不同的运作模式；自动计算和控制一个程序的主要规格，为每个治疗子系统计算吸收剂量、功率以及功率密度和一个疗程的持续时间；控制大频带激光发生器的功率和调制频率。
所述患者功能状态快速诊断系统2通过所述扫描仪3获取患者心率变异性的功能分析、功能状态电击穿诊断、测量和分析大脑超循环活动情况和呼吸频率漂移分析。
所述患者功能状态快速诊断系统2获得人体作为一个有机整体的各个器官和系统的功能状态的可靠信息，为疾病的早期诊断提供依据；对符合功能的系统或器官进行病理检查；选择最有效的治疗方法；在治疗过程结束之前、期间和结束时，对患者的病情进行公正的评估，其优点：无创，诊断程序简单，检查结果快，自述能力强。
所述扫描仪2结合或选择性采用氦氖和/或红外激光进行身体多区域扫描，扫描频率高达100-150Hz，最大定位区域(200*100sm)，可自动从一个区域过渡到另一个区域进行大批量快速扫描，且智能化计算扫描照射剂量。
优选的，所述扫描仪系统平均输出功率为35-40mVt。
所述太赫兹治疗子系统6采用太赫兹振冲按摩61、激光振动推拿62、磁激光63模块，实现太赫兹磁疗。
所述红外治疗子系统7采用磁喷嘴红外调制模块71和磁喷嘴红外固定脉冲模块72，实现红外热疗。
优选的，所述红外调制波长0.81-0.89微米，频率0-10000Hz，其中，0-100Hz内频率离散值为0.01，100Hz以上的离散值设置为1Hz。
优选的，所述红外脉冲波长0.80-0.95微米，频率0-5000Hz，其中，0-100Hz内频率离散值为0.01，100Hz以上的离散值设置为1Hz。
优选的，由于受红外调制和红外固定脉冲激光的影响，带有或不带有磁性安装附件的激光通过不同的方式：接触和接触压缩连接。
所述激光治疗系统5还采用氦氖激光模块51，实现激光疗法。
优选的，所述氦氖激光波长0.63微米。
优选的，由于氦氖激光对阴道、直肠、输尿管、鼻口、上腹壁、胃内腔及耳道粘膜表面的有效性，采用超过30种不同的光学喷嘴，实现泌尿科、妇科、直肠科、肺科、耳鼻喉科、齿科、消化科等腔器官疾病的治疗。
需要说明的是，所述激光疗法还可应用于美容领域。
优选的，采用经皮(LBI)或血管内(ILBI)激光血液照射系统；由于He-Ne激光对动脉支点投射区域和主要血管区域的有效性，采用循环血液的静脉内和动脉内照射。治愈关节炎、与血液循环障碍相关的疑难杂症(心肌梗死、IHD、血管末端疾病、糖尿病性肌病等)、内科炎症性疾病(肺炎、胃病等)、一般疾病(糖尿病、支气管哮喘、内分泌等)。
优选的，经皮(LBI)激光血液照射系统平均输出功率为15mVt。
优选的，血管内(ILBI)激光血液照射系统平均输出功率为5-10mVt。
所述水激光治疗子系统8配备水力喷头、妇科喷嘴和口腔科喷嘴，实现水激光活化疗法。
优选的，水激光系统平均输出功率为15-20mVt。
所述水激光治疗子系统8采用水按摩、低强度氦氖和/或红外线调制激光以及激光活化水的复杂作用，通过特殊喷嘴对阴道、口腔和皮肤的粘膜表面进行激光照射；实现身体状况的生物改变(消除抑郁症，神经和身体紧张，疼痛感，补充能量)，修复内分泌和植物神经系统的功能损伤，口腔黏膜表面炎症(副齿、溃疡)的治疗，妇科疾病的治愈。
所述诊疗床/诊疗椅4加载恒定磁场，与红外热疗、激光照射联合作用。
所述诊疗仪还设置有供电装置和控制开关。
所述各治疗子系统采用高联合策略以最佳模式进行组织，以太赫兹磁疗6(磁疗)、红外热疗7(热疗)、激光疗法5(光疗)为主，辅以水激光活化疗法8(水疗)，多功能综合性技术融合实现医疗诊断和治疗。
主要应用指征与适用范围：伤口愈合，软组织损伤，疼痛缓解，关节炎；浸入器官，血管，血流束，关节的创伤和疾病。
激光疗法的优势，改善微循环、再生、免疫刺激、单抗、抗肿瘤、脱敏、使新陈代谢和气体交换正常化。通过恒定、调制和脉冲的红色和红外激光辐射对针刺器官、器官投射、受体场、反射区和体表穴位的有效性，为治疗大量疾病提供了高临床效率。
临床疗效
中枢和外周神经系统：偏头痛、神经痛、神经病、骨软骨症、植物血管张力障碍等；
血液循环系统：脑血管性疾病、脑损伤、一、二级特发性高血压、反射性狭窄、下肢静脉曲张、心脏缺血性疾病、心肌梗死；
呼吸系统：慢性支气管炎、肺炎、支气管哮喘、气管等；
消化器官：胃及十二指肠溃疡、慢性胃溃疡、胃肠功能障碍、慢性胆囊炎、胰腺疾病等；
泌尿生殖系统：前列腺炎、尿道炎、性疾患、女性生殖器官炎症性疾病、不孕症、乳房炎、尿道下裂、尿道阻塞等；
运动障碍：假血肿、关节变形等；
皮肤病学：湿疹、神经性皮炎、荨麻疹、习惯性痤疮、牛皮癣、脱发、白癜风、单纯复发性疱疹、疖病；
手术病理：营养性溃疡、长时间不能愈合的伤口、燃烧、骨折、闭塞性动脉内膜和动脉粥样硬化、糖尿病性下肢动脉硬化、静脉炎、血栓性静脉咬伤；
预防和处理术后并发症；
耳鼻咽喉疾病：扁桃体炎、心绞痛、鼻炎、阴道炎、急慢性喉炎、咽炎、急慢性中耳炎、耳硬化症等；
牙科：牙槽炎，复发性口腔炎，牙周炎，齿槽炎，牙髓炎，龈炎，脓肿和面部发痰等；
嗜毒癖：嗜酒、吸烟、嗜睡症；
美容术：脸部皮肤、颈部(激光整容)、头枕部、脂肪团、局部组织积灰的轮廓矫正。
所述磁疗、热疗、光疗、水疗四大疗法可与治疗、手术、理疗、化疗、顺势疗法、芳香疗法、熏疗、休息活动等各种治疗和预防的医学方法相结合。
以上所述仅为本发明示意性的具体实施方式，仅用于解释说明本发明的发明构思，而非对本发明权利保护的限定，凡采用此构思对本发明进行非实质性的改动，均应落入本发明的保护范围。
Claims (10)
1.一种多功能综合性诊疗仪，其特征在于：
包括患者功能状态快速诊断系统、扫描仪、诊疗床/诊疗椅、激光治疗系统、太赫兹治疗子系统、红外治疗子系统、水激光治疗子系统。
2.如权利要求1所述的多功能综合性诊疗仪，其特征在于，所述诊疗仪核心系统管理患者数据库，根据所述患者功能状态快速诊断系统的扫描报告，制定最佳治疗方案，提交给所述治疗系统操作执行。
3.如权利要求1和2所述的多功能综合性诊疗仪，其特征在于，所述患者功能状态快速诊断系统通过所述扫描仪获取患者心率变异性的功能分析、功能状态电击穿诊断、测量和分析大脑超循环活动情况和呼吸频率漂移分析。
4.如权利要求1和3所述的多功能综合性诊疗仪，其特征在于，所述扫描仪结合或选择性采用氦氖和/或红外激光进行身体多区域扫描，扫描频率高达100-150Hz，最大定位区域(200*100sm)，可自动从一个区域过渡到另一个区域进行大批量快速扫描，且智能化计算扫描照射剂量。
5.如权利要求1所述的多功能综合性诊疗仪，其特征在于，所述太赫兹治疗子系统采用太赫兹振冲按摩、激光振动推拿、磁激光模块，实现太赫兹磁疗。
6.如权利要求1所述的多功能综合性诊疗仪，其特征在于，所述红外治疗子系统采用磁喷嘴红外调制模块和磁喷嘴红外固定脉冲模块，实现红外热疗。
7.如权利要求1所述的多功能综合性诊疗仪，其特征在于，所述激光治疗系统还采用氦氖激光模块，实现激光疗法。
8.如权利要求1所述的多功能综合性诊疗仪，其特征在于，所述水激光治疗子系统配备水力喷头、妇科喷嘴和口腔科喷嘴，实现水激光活化疗法。
9.如权利要求1所述的多功能综合性诊疗仪，其特征在于，所述诊疗床/诊疗椅加载恒定磁场，与红外热疗、激光照射联合作用；所述诊疗仪还设置有供电装置和控制开关。
10.如权利要求1至9所述的多功能综合性诊疗仪，其特征在于，所述各治疗子系统采用高联合策略以最佳模式进行组织，以太赫兹磁疗(磁疗)、红外热疗(热疗)、激光疗法(光疗)为主，辅以水激光活化疗法(水疗)，多功能综合性技术融合实现医疗诊断和治疗，可应用的医疗领域广泛：神经学、心脏病学、胃肠病学、创伤学、整形外科、手术、皮肤病学、牙科、泌尿外科和肾脏学、妇科、耳鼻喉科学和运动医学等。
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Cited By (1)
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| CN113855893A (zh) * | 2021-09-24 | 2021-12-31 | 深圳美丽魔方健康科技有限公司 | 一种红外富氢智能水疗仪 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103170064A (zh) * | 2013-03-27 | 2013-06-26 | 深圳先进技术研究院 | 诊疗一体探头 |
| CN103932680A (zh) * | 2014-04-15 | 2014-07-23 | 广州玖玖伍捌信息科技有限公司 | 一种人体肿瘤复发监测及热疗一体系统 |
| CN203802599U (zh) * | 2014-04-14 | 2014-09-03 | 北京天人即和科技有限公司 | 一种水激光牙科治疗仪 |
| KR20170004341A (ko) * | 2015-07-02 | 2017-01-11 | 최동환 | 테라헤르츠파를 이용한 저주파 자극 치료 겸용 복합 기능 물리 치료기 |
| CN106806996A (zh) * | 2017-02-24 | 2017-06-09 | 武汉洛芙科技股份有限公司 | 诊断和治疗一体化激光理疗智能机器人及控制方法 |
| CN108185989A (zh) * | 2017-12-28 | 2018-06-22 | 中国人民解放军陆军军医大学第附属医院 | 早期乳腺疾病多功能诊断治疗仪及控制方法 |
| RU2666121C1 (ru) * | 2017-09-18 | 2018-09-05 | федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации | Способ лечения больных с посттравматическим поражением головного мозга в раннем периоде заболевания |
| CN110384868A (zh) * | 2018-04-23 | 2019-10-29 | 清华海峡研究院（厦门） | 一种用于老年病预防和康复治疗的医疗设备 |
-
2020
- 2020-04-07 CN CN202010271678.9A patent/CN111408058A/zh active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103170064A (zh) * | 2013-03-27 | 2013-06-26 | 深圳先进技术研究院 | 诊疗一体探头 |
| CN203802599U (zh) * | 2014-04-14 | 2014-09-03 | 北京天人即和科技有限公司 | 一种水激光牙科治疗仪 |
| CN103932680A (zh) * | 2014-04-15 | 2014-07-23 | 广州玖玖伍捌信息科技有限公司 | 一种人体肿瘤复发监测及热疗一体系统 |
| KR20170004341A (ko) * | 2015-07-02 | 2017-01-11 | 최동환 | 테라헤르츠파를 이용한 저주파 자극 치료 겸용 복합 기능 물리 치료기 |
| CN106806996A (zh) * | 2017-02-24 | 2017-06-09 | 武汉洛芙科技股份有限公司 | 诊断和治疗一体化激光理疗智能机器人及控制方法 |
| RU2666121C1 (ru) * | 2017-09-18 | 2018-09-05 | федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации | Способ лечения больных с посттравматическим поражением головного мозга в раннем периоде заболевания |
| CN108185989A (zh) * | 2017-12-28 | 2018-06-22 | 中国人民解放军陆军军医大学第附属医院 | 早期乳腺疾病多功能诊断治疗仪及控制方法 |
| CN110384868A (zh) * | 2018-04-23 | 2019-10-29 | 清华海峡研究院（厦门） | 一种用于老年病预防和康复治疗的医疗设备 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113855893A (zh) * | 2021-09-24 | 2021-12-31 | 深圳美丽魔方健康科技有限公司 | 一种红外富氢智能水疗仪 |
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