CN111369853A - Medical integrated experimental teaching system and implementation method thereof - Google Patents

Medical integrated experimental teaching system and implementation method thereof Download PDF

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Publication number
CN111369853A
CN111369853A CN202010196981.7A CN202010196981A CN111369853A CN 111369853 A CN111369853 A CN 111369853A CN 202010196981 A CN202010196981 A CN 202010196981A CN 111369853 A CN111369853 A CN 111369853A
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experiment
data
experimental
physiological
human body
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高俊辉
林茂辉
高兴亚
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Shanghai Mengzhilu Digital Technology Co ltd
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Shanghai Mengzhilu Digital Technology Co ltd
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B9/00Simulators for teaching or training purposes
    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B7/00Electrically-operated teaching apparatus or devices working with questions and answers
    • G09B7/02Electrically-operated teaching apparatus or devices working with questions and answers of the type wherein the student is expected to construct an answer to the question which is presented or wherein the machine gives an answer to the question presented by a student

Abstract

The invention discloses a medical integrated experimental teaching system and a realization method thereof, wherein the system comprises: animal experiment and human physiological function test experiment hardware; the physiological signal integration operation platform is used for fusing and receiving biological signals of animal experiments and human physiological function test experiment hardware, converting the biological signals into data types with uniform formats and then sending the data types to the experiment teaching system; the experimental teaching system receives experimental target information and physiological measurement data transmitted by the physiological signal integration operation platform, and constructs real-time dynamic simulation animation and graphic teaching contents centering on an organ system according to the physiological measurement data of the experimental target or by combining the data simulated by operation of a human physiological drive engine with the physiological measurement data of the experimental target; and the system server cluster is responsible for access response of experimental course resources and balanced loading task allocation, starts corresponding computing nodes for computing based on a human physiological drive engine, and sends data to the experimental teaching system in real time.

Description

Medical integrated experimental teaching system and implementation method thereof
Technical Field
The invention relates to the technical field of medical experiment teaching, in particular to a medical integrated experiment teaching system based on physiological drive and an implementation method thereof.
Background
The medical experiment teaching plays an extremely important role in medical education, and at present, in the development process of the medical function teaching, disciplines are relatively independent, and the animal experiment verification theory teaching is taken as a main purpose. However, with the rise of animal experiment cost and the development of animal protection concept, the method is gradually applied to an experiment teaching system of medical function by a digital virtual simulation experiment and a human body non-invasive function test experiment.
The existing medical teaching experiment system mainly has the following defects:
1. the development of animal experiment teaching and human body non-invasive function experiment teaching requires separate experimental equipment and an experimental data processing system, so that the variety of the experimental equipment is multiple, the field consumption of schools is increased, the cost is high, and the management of instruments and equipment is complex.
2. In experimental teaching, students can only understand theoretical knowledge according to the change of test data of animals or human bodies and the analysis of teachers, and there is no intuitive explanation animation for the change of physiological and pathological mechanisms of organ systems, and there is no detection data imaging analysis which is commonly used in clinic.
3. The method is characterized in that a digital virtual simulation experiment is developed, teaching software lacks an algorithm model based on physiological drive, experiment teaching steps mainly adopt linear propulsion, experimental data results of different learning users are the same, the learning users cannot perform free and open operation learning functions, and a special experimental data analysis software tool similar to an entity experiment is lacked.
4. Animal experiment teaching, human function experiment teaching, virtual simulation experiment teaching are independent, so that the teacher needs to complete experiment examination and experiment report reading of students through different method modes and tools, the complexity of examining and approving different system data by the teacher is increased, and great workload is brought to experiment teaching workers. And meanwhile, the time cost for the learning user to generate the experiment report through different experiment systems and different experiment data is increased.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide a medical integrated experimental teaching system and an implementation method thereof, so as to solve the problem that three experimental system devices and experimental data platforms for developing medical functional animal experiments, human body functional test experiments and virtual simulation experiments are independent and incompatible at present.
To achieve the above object, the present invention provides a medical integrated experimental teaching system, which comprises:
the animal experiment hardware is used for acquiring animal experiment data in real time by using an animal experiment sensor, and processing the animal experiment data to form a biological signal of an animal experiment to the physiological signal integration operation platform;
human body physiological function test experiment hardware is used for acquiring human body physiological indexes in real time through human body signal acquisition equipment, processing the human body physiological indexes to form biological signals of the human body physiological function test experiment, and transmitting the biological signals to a physiological signal integration operation platform
The physiological signal integration operation platform is used for fusing and receiving biological signals of animal experiment hardware and human body physiological function test experiment hardware, integrating the biological signals into data interfaces of the same type by utilizing different drivers, respectively converting the obtained biological signals into data types of a uniform format, and then sending the data to an experiment teaching system;
the experiment teaching system is internally provided with all animal experiments, human body physiological function test experiments and virtual simulation experiment courses and is used for receiving experiment target information and physiological measurement data of an experiment target transmitted by a physiological signal integration operation platform and constructing real-time dynamic simulation animation and graphic teaching contents centering on an organ system according to the physiological measurement data of the experiment target or data simulated by operation of a human body physiological drive engine and combined with the physiological measurement data of the experiment target;
the system server cluster is used for being responsible for access response of experimental course resources and balanced loading task allocation, starting corresponding computing nodes to carry out computation based on a human physiological driving engine, feeding back data obtained by computation to an experimental teaching system in real time, and meanwhile, receiving, storing and uploading various experimental data.
Preferably, the animal experiment hardware comprises a plurality of animal experiment sensors, transducers, an AD converter and a hardware filter, wherein each animal experiment sensor acquires signals of an animal experiment, data are input into the AD converter through the transducers of different types for analog-to-digital conversion, and the converted data are filtered through the hardware filter to form biological signals of the animal experiment and are transmitted to the physiological signal integration operation platform.
Preferably, the animal experiment hardware is connected with the physiological signal integration operation platform through hardware.
Preferably, the human body physiological function test experiment hardware comprises a plurality of human body signal acquisition devices and a control unit, and each human body signal acquisition device acquires a corresponding human body physiological function test experiment signal, and the corresponding human body physiological function test experiment signal is processed by the control unit and then transmitted to the physiological signal integration operation platform.
Preferably, the human body physiological function test experiment hardware is in wireless connection with the physiological signal integration operation platform.
Preferably, the physiological signal integration operation platform comprises an animal experiment driving module and a network driving module, when receiving a biological signal of an animal experiment, the animal experiment driving module arranges the experiment data into a uniform format data type, outputs the biological signal of the animal experiment with the uniform format data type to the experiment teaching system, and when receiving the biological signal of the human physiological function test experiment, converts the biological signal into the uniform format data type through the network driving module, and sends the biological signal of the human physiological function test experiment with the uniform format data type to the experiment teaching system.
Preferably, the system server cluster includes:
the experiment platform server is responsible for storing and managing experiment course resources, and is used for being responsible for access response and balanced loading task allocation of the experiment course resources when a user logs in the virtual simulation experiment platform to perform an experiment;
the human physiology driving operation server is loaded with a human physiology driving engine program, when the human physiology driving engine receives a request, a corresponding computing node is started to compute, and then data are fed back to the experiment teaching system in real time;
and the experimental data workstation processing server is used for receiving various uploaded experimental data.
Preferably, the medically integrated experimental teaching system further comprises:
and the virtual simulation experiment equipment end is used for logging in the experiment courses on the virtual simulation experiment platform to perform online learning.
Preferably, the medically integrated experimental teaching system further comprises:
experimental data workstation equipment end, including teacher's end and student's end, the student end contains online examination, data analysis, experiment report generation module, the student end logs on the experimental data workstation through authentication, downloads the experimental data of three kinds of experiments of animal experiment, human physiology function test experiment and virtual simulation experiment, compares, analyzes and mark to experiment operation item and experimental data, generates the experiment report according to the frame format of experiment report, the teacher's end contains modules such as user management, experiment course management and editor, user real time monitoring, score statistics, experiment report reading, and the teacher's end logs on through teacher's authentication, looks over the experimental score, the experiment report of the student end of examining management to accomplish corresponding reading and score statistics work.
In order to achieve the above object, the present invention further provides a method for implementing a medical integrated experimental teaching system, comprising the following steps:
step S1, fusing and receiving biological signals of animal experiment hardware and human body physiological function test experiment hardware by using a physiological signal integration operation platform, integrating the biological signals into data interfaces of the same type by using different drivers, respectively converting the obtained biological signals into data types of a uniform format, and then providing experiment data to an experiment teaching system;
step S2, after receiving the experimental target information and the physiological measurement data of the experimental target transmitted by the physiological signal integration operation platform, the experimental teaching system acquires the index data which is not obtained from the experimental target according to the index data required by the teaching content and sends a request to the human physiological driving engine of the system server cluster to obtain the index data which is not obtained from the experimental target;
and step S3, the experimental teaching system constructs real-time dynamic simulation animation and graphic teaching contents centering on the organ system according to the physiological measurement data of the experimental target or index data obtained by utilizing the operation of the human physiological drive engine and combining the physiological measurement data of the experimental target.
Compared with the prior art, the medical integrated experimental teaching system and the realization method thereof can integrate the physiological signal integration operation platform of animal experiments and human body physiological function test experiments, eliminate the current situation that animal experiments and human body function test experimental equipment are not compatible, the invention can also support the data processing and operation online software systems of three experiments, namely an animal experiment, a human physiological function test experiment and a virtual simulation experiment, reduces the workload of a teacher for examining and evaluating students in the experiment and teaching process at present, and also improves the experiment and teaching effect and the student learning efficiency.
Drawings
FIG. 1 is a system structure diagram of a medical integrated experimental teaching system according to the present invention;
FIG. 2 is a flow chart of the steps of a method for implementing the integrated medical experiment teaching system according to the present invention;
FIG. 3 is a schematic diagram illustrating an implementation of a physiological signal integration operation platform according to an embodiment of the present invention;
FIG. 4 is a schematic diagram of a real-time organ simulation system based on experimental data according to an embodiment of the present invention.
Detailed Description
Other advantages and capabilities of the present invention will be readily apparent to those skilled in the art from the present disclosure by describing the embodiments of the present invention with specific embodiments thereof in conjunction with the accompanying drawings. The invention is capable of other and different embodiments and its several details are capable of modification in various other respects, all without departing from the spirit and scope of the present invention.
Fig. 1 is a system structure diagram of a medical integrated experimental teaching system according to the present invention. As shown in fig. 1, the present invention provides a medical integrated experimental teaching system, which includes: a
The animal experiment hardware 10 is used for acquiring animal experiment data in real time by using an animal experiment sensor, and processing the animal experiment data to form a biological signal of an animal experiment and transmit the biological signal to the physiological signal integration operation platform 30.
In the embodiment of the present invention, the animal experiment hardware 10 includes an animal experiment sensor, a transducer, an AD converter, and a hardware filter, specifically, the animal experiment sensor acquires signals of an animal experiment, inputs data into the AD converter through different types of transducers for analog-to-digital conversion, and filters the data through the hardware filter after the conversion to form biological signals of the animal experiment, and then transmits the biological signals to the physiological signal integration operation platform 30. In specific embodiments of the present invention, the animal experiment sensor includes, but is not limited to, a blood pressure sensor, an arterial cannula, an electrocardiograph clamp, an arterial clamp, and the like. It should be noted that the animal experiment hardware 10 can be connected to the physiological signal integration operation platform 30 through a hardware connection (e.g. USB), but the invention is not limited thereto.
The human body physiological function test experiment hardware 20 is used for acquiring human body physiological indexes in real time through a human body signal acquisition device, processing the human body physiological indexes to form biological signals of the human body physiological function test experiment, and transmitting the biological signals to the physiological signal integration operation platform 30.
In a specific embodiment of the present invention, the human physiological function test experiment hardware 20 includes a plurality of human signal collecting devices and a control unit, the human signal collecting devices include but are not limited to a breath test module, a finger pressure pulse test module, an electrocardiogram module, a body temperature module, a myoelectric collecting module, etc., each human signal collecting device collects a corresponding human physiological function test experiment signal, and the corresponding human physiological function test experiment signal is processed by the control unit and then transmitted to the physiological signal integration operation platform 30. In the embodiment of the present invention, the human physiological function test experiment hardware 20 is wirelessly connected to the physiological signal integration operation platform 30.
The physiological signal integration operation platform 30 is used for receiving biological signals of the animal experiment hardware 10 and the human body physiological function test experiment hardware 20 in a fusion manner, integrating the biological signals into data interfaces of the same type by using different drivers, converting the obtained biological signals into data types of a uniform format respectively, and then sending the data to the experiment teaching system 40.
In a specific embodiment of the present invention, the physiological signal integration operation platform 30 includes an animal experiment driving module and a network driving module, when receiving a biological signal of an animal experiment, the animal experiment driving module arranges the experiment data into a uniform format data type, and outputs the biological signal of the animal experiment of the uniform format data type to the experiment teaching system 40, and when receiving the biological signal of the human physiological function test experiment, the biological signal of the human physiological function test experiment of the uniform format data type is converted into the uniform format data type by the network driving module, and then the biological signal of the human physiological function test experiment of the uniform format data type is sent to the experiment teaching system 40.
The experiment teaching system 40 is internally provided with all animal experiments, human body physiological function test experiments and virtual simulation experiment courses and is used for receiving experiment target information and physiological measurement data of an experiment target transmitted by a physiological signal integration operation platform and constructing real-time dynamic simulation animation and graphic teaching contents centering on an organ system according to the physiological measurement data of the experiment target or data simulated by operation of a human body physiological drive engine and the physiological measurement data of the experiment target. That is, in the experiment teaching system 40 of the present invention, all the animal experiments, the human physiological function tests and the virtual simulation experiment courses in the integrated experiment teaching system of the present invention are built in, each experiment course includes an experiment operation guidance, an experiment data acquisition and an organ real-time simulation teaching system, a learning user can develop corresponding experiment learning according to the experiment operation guidance, for the human function test data, a novel real-time dynamic simulation animation and graphic teaching content centered on the organ system is constructed by combining the data of the operation simulation with the human function test experiment data based on the human physiological driving engine, and the defect that the internal change process of the living organism cannot be seen in the experiment process is overcome. The experiment teaching system 40 is connected to the system server cluster 50 through a network.
The human physiology driving engine program is loaded on a human physiology driving operation server 502 of the system server cluster 50, is based on a Standardized virtual simulated Patient (Electronic simulated Patient, ESP virtual Patient) of physiology driving, is based on a human physiology system theory, and is a set of physiology driving-based mechatronics digital human system developed by integrating medical, physical and mathematical comprehensive technologies to realize simulation and functional model design of a human organ system. The human physiology driving engine can comprehensively simulate the change of the functions of the living organisms in the human physiology, pathophysiology and pharmacology states, and a learning user can complete a medical experiment task in a more accurate and highly clinical state through a system case.
Taking the experimental teaching of the cardio-pulmonary motion function of a human body physiological test experiment as an example, the experimental teaching system receives physiological measurement data from an experimental human body and recorded experimental human body information, sends a request to a human body physiological drive engine according to index data which are required by teaching contents and cannot be measured from the experimental human body, such as 'stroke volume', 'cardiac output', 'cardiac index', 'oxygen consumption', and the like, and sends data feedback to the experimental teaching system after calculation, so that real-time dynamic simulation animation and graphic teaching contents are constructed, and the experimental human body information includes but is not limited to 'sex', 'age', 'height', 'weight', and the like. It should be noted here that only human physiology experiments are combined with the human physiology driving engine, the data can be conveniently obtained in an invasive manner in the animal experiment process, and the human physiology experiments cannot be subjected to invasive measurement, so that index data which cannot be measured from the experimental human body need to be obtained through the human physiology driving engine.
The system server cluster 50 is used for enabling a user to log in a virtual simulation experiment platform to perform experiments, and is responsible for access response of experiment course resources and balanced loading task allocation, when the experiment teaching system 40 is started to operate development of illness states of virtual animals or virtual patients in an experiment scene, corresponding computing nodes are started to perform computing based on a human physiology driving engine, data are sent to experiment software of the experiment teaching system in real time, and meanwhile the system server cluster 50 receives various uploaded experiment data.
Specifically, the system server cluster 50 includes:
the virtual simulation experiment platform server 501 is mainly responsible for storing and managing experiment course resources, in the embodiment of the present invention, the experiment course includes all animal experiments, human physiological function test experiments, and virtual simulation experiment courses, and the virtual simulation experiment courses include but are not limited to teaching modules of basic animal operations, respiratory systems, cardiovascular systems, digestive systems, nervous and motor systems, urinary systems, drug action and mechanism systems thereof, and comprehensive experiments. When a user logs in the virtual simulation experiment platform through the virtual simulation experiment equipment terminal 60 to perform an experiment, the virtual simulation experiment platform server 501 is responsible for access response of experiment course resources and balanced loading task allocation.
The human physiology driving operation server 502 is loaded with a human physiology driving engine program, the engine is based on a physiological driving Standardized virtual simulation Patient (ESP virtual Patient), is based on a human physiology system theory, and realizes the simulation of a human organ system and the design of a functional model by integrating medical, physical and mathematical comprehensive technologies, thereby developing a set of physiological driving based mechanotronics digital human system. The human physiology driving engine can comprehensively simulate the change of the functions of the living organisms in the human physiology, pathophysiology and pharmacology states, and a learning user can complete a medical experiment task in a more accurate and highly clinical state through a system case. When the calculation of the disease development of the virtual animal or the virtual patient in the experimental scene is started, a request is sent to the human physiology driving calculation server 502, the human physiology driving calculation server 502 starts the corresponding calculation node for calculation, and then the data is sent to the virtual simulation experimental equipment end 60 in real time.
The experiment data workstation processing server 503 is configured to receive various uploaded experiment data. In the invention, the experimental data comprises data of three experiments, namely an animal experiment, a human body physiological function test experiment and a virtual simulation experiment.
And the virtual simulation experiment equipment end 60 is used for logging in the experiment courses on the virtual simulation experiment platform to perform online learning. In the embodiment of the present invention, the virtual simulation experiment equipment terminal 60 includes, but is not limited to, a PC computer, an Ipad tablet computer, and a smart phone
The experimental Data workstation equipment end 70 comprises a teacher end and a student end, wherein the student end comprises an online examination module, a Data analysis module and an experimental report generation module, the system can support Data processing analysis of three experiments including an animal experiment, a human body physiological function test experiment and a virtual simulation experiment, a learning user logs in an experimental Data workstation (Lab Data Station) through identity authentication by using the experimental Data workstation equipment end 70, can download experimental Data of the three experiments including the animal experiment, the human body physiological function test experiment and the virtual simulation experiment, compares, analyzes and labels experimental operation items and experimental Data, and generates an experimental report according to a frame format of the experimental report; the teacher end of the experiment Data workstation (Lab Data Station) comprises modules of user management, experiment course management and editing, user real-time monitoring, score statistics, experiment report reading and the like. The teacher end of the experiment Data workstation (Lab Data Station) can log in the system of the invention through the teacher identity authentication by the teacher end of the experiment lesson, and check the experimental examination scores and the experimental reports of the class students to finish the corresponding reading and score counting work.
Fig. 2 is a flowchart illustrating steps of a method for implementing a medical integrated experimental teaching system according to the present invention. As shown in fig. 2, the implementation method of a medical integrated experimental teaching system of the present invention includes the following steps:
and step S1, fusing and receiving biological signals of animal experiment hardware and human body physiological function test experiment hardware by using a physiological signal integration operation platform, integrating the biological signals into data interfaces of the same type by using different drivers, respectively converting the obtained biological signals into data types of a uniform format, and then providing the experiment data to an experiment teaching system.
In the specific embodiment of the invention, an animal experiment sensor acquires signals of an animal experiment, data are input into an AD converter for analog-to-digital conversion through different types of transducers, and the data are filtered through a hardware filter after conversion to form biological signals of the animal experiment and then are transmitted to a physiological signal integration operation platform; each human body signal acquisition device acquires a corresponding human body physiological function test experimental signal, and the corresponding human body physiological function test experimental signal is processed by the control unit and then transmitted to the physiological signal integration operation platform; when receiving the biological signal of the human body physiological function test experiment, the physiological signal integration operation platform converts the biological signal of the human body physiological function test experiment of the unified format data type into the unified format data type through a network driving module, and then sends the biological signal of the human body physiological function test experiment of the unified format data type to the experiment teaching system.
Step S2, after receiving the information of the experimental target and the physiological measurement data of the experimental target transmitted by the physiological signal integration operation platform, the experimental teaching system obtains the index data not obtained from the experimental target according to the index data required by the teaching content and sends a request to the human physiological driving engine of the system server cluster to obtain the index data not obtained from the experimental target.
In the embodiment of the invention, since the human physiology experiment can not receive invasive measurement, the biological signal obtained from the human physiology function test experiment hardware can not meet the index data required by the teaching content, and therefore, the index data which can not be measured from the experimental human body can be obtained through the human physiology driving engine. The human physiology driving engine program is carried on a human physiology driving operation server of a system server cluster, is based on a Standardized virtual simulated Patient (Electronic standard Patient, ESP virtual Patient) of physiology driving, is established on the theoretical basis of a human physiology system, and realizes the simulation of an organ system of a human body and the design of a functional model by integrating comprehensive technologies of medicine, physics and mathematics, thereby developing a set of mechanotronics digital human system based on physiology driving. The human physiology driving engine can comprehensively simulate the change of the functions of the living organisms in the human physiology, pathophysiology and pharmacology states, and a learning user can complete a medical experiment task in a more accurate and highly clinical state through a system case. And after receiving the request, the human physiological driving engine starts a corresponding computing node to compute, and then feeds data back to the experiment teaching system.
And step S3, the experimental teaching system constructs real-time dynamic simulation animation and graphic teaching contents centering on the organ system according to the physiological measurement data of the experimental target or index data obtained by utilizing the operation of the human physiological drive engine and combining the physiological measurement data of the experimental target.
Examples
Fig. 3 is a schematic diagram illustrating an implementation of a physiological signal integration operation platform according to an embodiment of the present invention. In the embodiment of the invention, the animal experiment hardware 11 can collect animal experiment data in real time, the human physiological function test experiment hardware 15 can collect human physiological indexes in real time, the human physiological indexes are integrated into the same type of data interface through different drivers, and the data interface is transmitted to the experiment teaching software of the integrated experiment teaching system for data analysis and operation. Specifically, signals acquired by the animal experiment sensor are input into the AD converter through the transducers 12 of different types for analog-to-digital conversion, the converted signals are filtered by the hardware filter, then the data are transmitted to the animal experiment driving module 13 through the USB protocol, the animal experiment driving module 13 arranges and converts the experiment data into data types of a uniform format (17), and then the acquired data are output to the experiment teaching software 18 of the experiment teaching system. Signals collected by each index testing suite module 14 in the human body physiological function testing experiment hardware 15 are transmitted to the data server 16 through the WIFI through the control unit, and after the signals are converted into data types with uniform formats through the network driving module (17), the data are sent to experiment teaching software 18 of an experiment teaching system.
In the embodiment of the present invention, the integrated experiment teaching system of the present invention includes an experiment teaching system, an experiment report system, an experiment database (in the experiment data workstation 503), and the like, and the experiment teaching system can control experiment hardware to perform experiment operations, can display experiment data in real time, can perform data analysis on the real-time data, and can log the member account numbers in the same group into the integrated experiment software to perform experiment data management during the experiment operations. When the experiment is carried out, the experiment teaching system can transmit the experiment data and the information of the experimenter to the experiment report system and store the experiment data and the information of the experimenter in the experiment database. After the experiment is completed, students can log in the experiment report system respectively to check own experiment data, and write experiment reports. After the report is submitted, the teacher can check the experimental process, experimental data and final experimental report of the student through the experimental report system
In the embodiment of the invention, a brand-new experiment course system and content of a teaching system taking an organ system as a center are established, and each experiment course is divided into four links of theoretical teaching, basic experiments, extended experiments, analysis summary and case examination. Wherein the teaching forms of the basic experiment and the extended experiment comprise three experiment teaching forms of an animal experiment, a human body physiological function test experiment and a virtual simulation teaching experiment
Animation or graphic teaching of experimental data for simulating the motion of an organ system in real time is explained by an implementation example of a human physiological function experiment of heart and lung motion function as follows:
the general implementation of this experimental course is as follows: a student is selected as an experimental object, the student is worn with a noninvasive blood pressure measurement and electrocardiogram detection kit and a spirometer, the blood pressure, the heart rate, the respiratory frequency, the respiratory capacity and the flow of the student are measured in a resting state, the electrocardiogram of the student is detected, then the student performs sports through equipment such as a bicycle dynamometer or a running dynamometer, and the physiological indexes of the student are measured again in the sports and after the sports. The effect of intense exercise on cardiopulmonary function was analyzed by experimental data.
The technical scheme is that under the condition that physiological indexes of a human body are insufficient in measurement under a non-invasive state, other indexes of the human body can be compensated through calculation of a human body physiological driving engine, and then the motion of a 3D human body organ and the display of other physiological indexes are driven in real time through comprehensive application of all the indexes, so that a better teaching effect is achieved.
As shown in fig. 4, 19 is a human physiological test experiment (student) subject, and is worn with an experimental apparatus such as a noninvasive blood pressure measurement and electrocardiogram detection kit, a spirometer, etc. The experimental instrument transmits the human body physiological index data to the experiment teaching software 20 connected with the physiological signal integration operation platform through the wireless network WIFI.
In the figure 20, human body physiological function experiment teaching software of 'heart and lung movement function' is provided, and the software comprises an experiment purpose, experiment operation guidance, experiment data acquisition and real-time simulation organ movement teaching system. The software can receive physiological measurement data from an experimental human body and input information of the experimental human body. The software can send a request to the human body physiological driving engine 22 according to index data which can not be measured from experimental human bodies, such as 'stroke volume', 'cardiac output', 'cardiac index', 'oxygen consumption', and the like required by teaching contents, and the data is fed back to the software after calculation.
Before the experiment, the experimenter enters the information (21) of the sex, the age, the height, the weight and the like of the experimental human body into the experiment teaching software 20.
In the figure 23 is the "cardiac output" index, which cannot be measured by a non-invasive experimental device of a human body, and is a key index parameter, because other parameter indexes such as "stroke volume", "heart index", "oxygen consumption" and the like can be calculated according to the "cardiac output" index and the heart rate and other related parameters.
Cardiac output is calculated according to "simple method of assessing cardiac output", using patient size modification of the Starr pulse pressure formula and the formula measured using standard thermodilution techniques to calculate the accuracy of the formula for cardiac output. The calculation of cardiac output applied by the present invention is:
SV=(100-0.6Age-0.6DP+0.5PP*BSA(m2))/1.7
wherein SV represents cardiac output, Age represents Age, DP (diastolic pressure) represents systolic pressure, PP (pulsepresssure) represents pulse pressure difference, the numerical value represents systolic pressure minus diastolic pressure, and BSA represents the human body surface area of the subject in square meters.
According to the common human body surface area estimation method in China, the formula of Schwensheng is as follows:
BSA(male)=0.0057H+0.0121W+0.0882
BSA(female)=0.007H+0.0127W-0.2106
in the above formula, male represents male, female represents female, H represents height, and W represents weight.
From the above, it can be obtained that the clinical common indicators of the human body, such as cardiac output, stroke volume, cardiac index, oxygen consumption, etc., can be calculated more accurately as long as the sex, age, height, weight, blood pressure and heart rate of the experimental subject (normal human body) are known.
Fig. 24 shows a schematic representation of the 3D heart beat and myocardial potential conduction animation, with the beat frequency of the heart driven by the measured heart rate (sub/min) data of the experimental human. The amplitude of the heart beat is converted into the ratio of the stroke volume (ml) in the resting state by the stroke volume (ml) calculated by the human physiological drive engine program to drive the amplitude of the heart beat. The heart myocardial potential conduction animation is driven by the real-time data of the electrocardiogram. Because the electrocardiogram and the conduction process of the cardiac muscle potential have a fixed corresponding relation.
The real-time simulation organ motion teaching system can simulate and display 3D heart beating animation in real time, also comprises other clinical indexes 25 of the tested human heart, can calculate corresponding data indexes according to different experimental objects, and has a great effect on the improvement of teaching quality.
Compared with the prior art, the invention has the following advantages:
1. the invention solves the problem that the experimental system equipment and the experimental data platform for the functional animal experiment, the human body function test experiment and the virtual simulation experiment carried out in the medical colleges are independent and incompatible at present.
2. By the aid of the method and the system, teachers can develop animal experiments, human body function test experiments and virtual simulation experiments only based on one set of experiment system equipment, purchase cost and quantity of equipment cost are reduced, and storage space is reduced.
3. By the aid of the method and the device, students can conduct experiments according to experiment operation in the experiment learning process, success rate of the experiments is improved, and real-time dynamic simulation animations and graphs of organ systems generated according to experiment data can be watched and learned in the experiment process, so that knowledge points of the experiments are deepened to be understood, and learning efficiency is improved.
4. According to the invention, in the experiment teaching process, a learning user can upload experiment data to the cloud, and then log in the functional experiment data workstation through identity authentication, so that the online software system for data processing and operation of three experiments, namely an animal experiment, a human body physiological function test experiment and a virtual simulation experiment, can be supported, the workload of a teacher for examining and evaluating students in the experiment teaching process is reduced, and the experiment teaching effect and the student learning efficiency are improved.
5. By the invention, an experiment instructor can log in an experiment teaching management system through identity authentication to read experiment reports and operation examination of all developed experiment courses, so that the class work of educators is greatly reduced, and the method has important value for reform and application of medical experiment teaching.
The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Modifications and variations can be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the present invention. Therefore, the scope of the invention should be determined from the following claims.

Claims (10)

1. A medically integrated experimental teaching system, comprising:
the animal experiment hardware is used for acquiring animal experiment data in real time by using an animal experiment sensor, and processing the animal experiment data to form a biological signal of an animal experiment to the physiological signal integration operation platform;
human body physiological function test experiment hardware is used for acquiring human body physiological indexes in real time through human body signal acquisition equipment, processing the human body physiological indexes to form biological signals of the human body physiological function test experiment, and transmitting the biological signals to a physiological signal integration operation platform
The physiological signal integration operation platform is used for fusing and receiving biological signals of animal experiment hardware and human body physiological function test experiment hardware, integrating the biological signals into data interfaces of the same type by utilizing different drivers, respectively converting the obtained biological signals into data types of a uniform format, and then sending the data to an experiment teaching system;
the experiment teaching system is internally provided with all animal experiments, human body physiological function test experiments and virtual simulation experiment courses and is used for receiving experiment target information and physiological measurement data of an experiment target transmitted by a physiological signal integration operation platform and constructing real-time dynamic simulation animation and graphic teaching contents centering on an organ system according to the physiological measurement data of the experiment target or data simulated by operation of a human body physiological drive engine and combined with the physiological measurement data of the experiment target;
the system server cluster is used for being responsible for access response of experimental course resources and balanced loading task allocation, starting corresponding computing nodes to carry out computation based on a human physiological driving engine, feeding back data obtained by computation to an experimental teaching system in real time, and meanwhile, receiving, storing and uploading various experimental data.
2. A medical integrated experimental teaching system as claimed in claim 1, wherein: the animal experiment hardware comprises a plurality of animal experiment sensors, transducers, AD converters and hardware filters, wherein each animal experiment sensor acquires signals of an animal experiment, data are input into the AD converters through the transducers of different types for analog-to-digital conversion, and the converted data are filtered through the hardware filters to form biological signals of the animal experiment and then are transmitted to the physiological signal integration operation platform.
3. A medical integrated experimental teaching system as claimed in claim 1, wherein: the animal experiment hardware is connected with the physiological signal integration operation platform through hardware.
4. A medical integrated experimental teaching system as claimed in claim 1, wherein: the human body physiological function test experiment hardware comprises a plurality of human body signal acquisition devices and a control unit, and each human body signal acquisition device acquires a corresponding human body physiological function test experiment signal and transmits the corresponding human body physiological function test experiment signal to the physiological signal integration operation platform after the corresponding human body physiological function test experiment signal is processed by the control unit.
5. A medical integrated experimental teaching system as claimed in claim 4, wherein: the human body physiological function test experiment hardware is in wireless connection with the physiological signal integration operation platform.
6. A medical integrated experimental teaching system as claimed in claim 1, wherein: the physiological signal integration operation platform comprises an animal experiment driving module and a network driving module, when receiving a biological signal of an animal experiment, the animal experiment driving module arranges the experiment data into a uniform format data type, outputs the biological signal of the animal experiment with the uniform format data type to an experiment teaching system, and when receiving the biological signal of a human physiological function test experiment, converts the biological signal into the uniform format data type through the network driving module, and sends the biological signal of the human physiological function test experiment with the uniform format data type to the experiment teaching system.
7. A medical integrated experimental teaching system as claimed in claim 1, wherein the system server cluster includes:
the experiment platform server is responsible for storing and managing experiment course resources, and is used for being responsible for access response and balanced loading task allocation of the experiment course resources when a user logs in the virtual simulation experiment platform to perform an experiment;
the human physiology driving operation server is loaded with a human physiology driving engine program, when the human physiology driving engine receives a request, a corresponding computing node is started to compute, and then data are fed back to the experiment teaching system in real time;
and the experimental data workstation processing server is used for receiving various uploaded experimental data.
8. A medical integrated experimental teaching system according to claim 7, further comprising:
and the virtual simulation experiment equipment end is used for logging in the experiment courses on the virtual simulation experiment platform to perform online learning.
9. A medical integrated experimental teaching system as claimed in claim 7, wherein: the integrated experimental teaching system of medical science further comprises:
experimental data workstation equipment end, including teacher's end and student's end, the student end contains online examination, data analysis, experiment report generation module, the student end logs on the experimental data workstation through authentication, downloads the experimental data of three kinds of experiments of animal experiment, human physiology function test experiment and virtual simulation experiment, compares, analyzes and mark to experiment operation item and experimental data, generates the experiment report according to the frame format of experiment report, the teacher's end contains modules such as user management, experiment course management and editor, user real time monitoring, score statistics, experiment report reading, and the teacher's end logs on through teacher's authentication, looks over the experimental score, the experiment report of the student end of examining management to accomplish corresponding reading and score statistics work.
10. A method for realizing a medical integrated experimental teaching system comprises the following steps:
step S1, fusing and receiving biological signals of animal experiment hardware and human body physiological function test experiment hardware by using a physiological signal integration operation platform, integrating the biological signals into data interfaces of the same type by using different drivers, respectively converting the obtained biological signals into data types of a uniform format, and then providing experiment data to an experiment teaching system;
step S2, after receiving the experimental target information and the physiological measurement data of the experimental target transmitted by the physiological signal integration operation platform, the experimental teaching system acquires the index data which is not obtained from the experimental target according to the index data required by the teaching content and sends a request to the human physiological driving engine of the system server cluster to obtain the index data which is not obtained from the experimental target;
and step S3, the experimental teaching system constructs real-time dynamic simulation animation and graphic teaching contents centering on the organ system according to the physiological measurement data of the experimental target or index data obtained by utilizing the operation of the human physiological drive engine and combining the physiological measurement data of the experimental target.
CN202010196981.7A 2020-03-19 2020-03-19 Medical integrated experimental teaching system and implementation method thereof Pending CN111369853A (en)

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