CN111351953A - Multi-needle linear module for chemiluminescence apparatus - Google Patents

Multi-needle linear module for chemiluminescence apparatus Download PDF

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Publication number
CN111351953A
CN111351953A CN202010306318.8A CN202010306318A CN111351953A CN 111351953 A CN111351953 A CN 111351953A CN 202010306318 A CN202010306318 A CN 202010306318A CN 111351953 A CN111351953 A CN 111351953A
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CN
China
Prior art keywords
needle
linear module
sliding seat
sample
pin
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010306318.8A
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Chinese (zh)
Inventor
杜康
刘新全
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Tianjin Boom Science Co ltd
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Tianjin Boom Science Co ltd
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Publication date
Application filed by Tianjin Boom Science Co ltd filed Critical Tianjin Boom Science Co ltd
Priority to CN202010306318.8A priority Critical patent/CN111351953A/en
Publication of CN111351953A publication Critical patent/CN111351953A/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/763—Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N2021/0106—General arrangement of respective parts
    • G01N2021/0112—Apparatus in one mechanical, optical or electronic block
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention relates to a multi-needle linear module for a chemiluminescence instrument, which comprises a driving part, a connecting part, a base and a sample adding needle module, wherein at least two independent sample adding needle modules are arranged on the base side by side; the base comprises a bottom plate and at least two sliding rails positioned on the bottom plate; the sample adding needle module comprises a sliding seat and a sample adding needle arranged on the sliding seat, and a sliding groove matched with the sliding rail is arranged on the bottom surface of the sliding seat; the transmission part is a belt driven by the driving part to move. The multi-needle linear module for the chemiluminescence instrument can add a plurality of samples simultaneously, has higher efficiency than the single application of one sample adding needle, does not generate sample intersection, and improves the sample detection accuracy.

Description

Multi-needle linear module for chemiluminescence apparatus
Technical Field
The invention relates to the technical field of sample adding needles for detection, in particular to a multi-needle linear module for a chemiluminescence instrument.
Background
At present, automatic sample adding needle modules are adopted in chemiluminescent instruments for sampling and injecting samples, so that the possibility of fine analysis of the samples is provided. The existing sampling needle modules are used independently, but the sampling needle used independently has low efficiency and may cross the samples, and in the medical industry, if two samples which cannot be crossed are crossed, the result may be serious. In addition, the existing sample adding needle module is a motor, and the rotating motion of the motor is converted into linear motion through a screw rod structure, however, the screw rod structure is high in cost, and the round trip stroke of the sample adding needle module driven by the screw rod structure is limited, so that the use freedom of the sample adding needle is limited.
The present invention is an improvement based on the above technical problems.
Disclosure of Invention
The invention provides a multi-needle linear module for a chemiluminescence apparatus aiming at the related problems in the background art, the multi-needle linear module can be used for simultaneously adding a plurality of samples, the efficiency is higher than that of singly using one sample adding needle, the sample intersection is avoided, and the sample detection accuracy is improved.
In order to solve the technical problems, the invention adopts the technical scheme that:
the multi-needle linear module for the chemiluminescence instrument comprises a driving piece, a connecting piece, a base and sample adding needle modules, wherein at least two independent sample adding needle modules are arranged on the base side by side;
the base comprises a bottom plate and at least two sliding rails positioned on the bottom plate;
the sample adding needle module comprises a sliding seat and a sample adding needle arranged on the sliding seat, and a sliding groove matched with the sliding rail is arranged on the bottom surface of the sliding seat;
the transmission part is a belt driven by the driving part to move.
Furthermore, the driving medium still includes around driving shaft and the driven shaft of establishing by the belt, the driving piece drives the driving shaft and rotates.
Further, the application of sample needle is including the needle cap portion, needle stalk portion, thick needle portion and the thin needle portion that connect in order, thin needle portion with thick needle portion all pegs graft and is fixed in the adapter, needle cap portion, needle stalk portion and thick needle portion body structure connect in order, needle stalk portion with be equipped with baffle portion between the thick needle portion.
Furthermore, the thick needle part is inserted into the jack of the sliding seat and can move relative to the jack; the sliding seat is positioned between the adapter and the baffle part; a spring is sleeved on the periphery of the thick needle part and is positioned between the sliding seat and the adapter; under the action of the spring, one end face of the sliding seat is abutted against the spring, and the other end face of the sliding seat is abutted against the baffle plate part.
Furthermore, a separation blade is clamped on the needle handle part.
Furthermore, the slide is a block structure and is provided with a concave sample adding needle mounting platform.
Furthermore, the connecting piece is a plate rib pressing piece and a bolt, the belt is located between the lower portion of the metal plate pressing piece and the sliding seat, and the upper portion of the metal plate pressing piece is fixed on the sliding seat through the bolt.
Furthermore, a liquid level detector is further arranged and installed on the upper surface of the sliding seat.
Furthermore, the device is also provided with a bottom contact detector, and the bottom contact detector is arranged on the side wall of the sample adding needle mounting table.
Further, the driving member is a motor.
The invention has the beneficial effects that:
(1) the multi-needle linear module can be used for simultaneously adding a plurality of samples, has higher efficiency than the single application of one sample needle, does not generate sample intersection, and improves the accuracy of sample detection; the plurality of sampling needle modules in the multi-needle linear module are independently arranged, are not influenced mutually, can be used independently or simultaneously, have flexible operation modes, can highly meet the requirements of users, and are convenient to install and maintain; the motors are all arranged on the back of the base, so that the space occupancy rate of the sampling needle module is improved;
(2) the driving piece changes the rotation motion into linear motion through the transmission rod with the belt property, the belt is long, the sample adding needle module can move along with the belt within half of the length of the belt, and the use freedom degree of the sample adding needle module is increased; the cost of the belt is lower than that of the lead screw structure, and the tolerance is strong;
(3) the liquid level detector can accurately judge the distance between the sample adding needle module and the liquid level to be detected; the bottom-touching detector can accurately set the distance between the bottom of the sample adding needle and the bottom of the liquid to be detected, and the liquid level detector and the bottom-touching detector supplement each other, thereby being beneficial to the smooth proceeding of the sampling process.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the multi-pin linear module in the embodiment;
FIG. 2 is a schematic structural diagram of a base in the embodiment;
FIG. 3 is a schematic view of a top-view perspective structure of a sample injection needle module in an embodiment;
FIG. 4 is a schematic view of the bottom perspective structure of the sample injection needle module in the embodiment;
FIG. 5 is a schematic perspective view of the slider in the embodiment in a front view;
FIG. 6 is a schematic perspective view of the slider in the embodiment in a rear view;
FIG. 7 is a schematic structural diagram of a sample injection needle in the example.
In the figure: 1. a base; 11. a base plate; 12. a slide rail; 2. a slide base; 21. a chute; 22. a jack; 23. a sample adding needle mounting table; 3. a sample adding needle; 31. a needle cap portion; 32. a needle handle; 33. a thick needle portion; 34. a fine needle portion; 35. a baffle plate; 36. a spring; 37. an adapter; 38. a baffle portion; 4. a transmission member; 41. a drive shaft; 42. a driven shaft; 43. a belt; 5. a connecting member; 51. sheet metal pressing; 52. a bolt; 6. a motor; 7. a liquid level detector; 8. a bottoming detector.
Detailed Description
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The fixed connection relationship which is not explicitly described in the invention can be one of welding, bonding, bolt connection and clamping. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.
In some embodiments, chemiluminescence appearance is with many needles straight line module, including driving piece, driving medium 4, connecting piece 5, base 1 and application of sample needle module, at least two independent settings application of sample needle module set up side by side on the base 1, the driving piece drives application of sample 4 moves, connecting piece 5 connect driving piece 4 with application of sample needle module for application of sample needle module moves along with driving medium 4, and application of sample needle 3's motion mode is for moving the location in the rectilinear direction for base 1.
The multi-pin linear module has at least two sample adding pin modules, as shown in fig. 1, and is a schematic diagram for setting two sample adding pins 3, and the two sample adding pin modules are mutually independent and can simultaneously test two samples which cannot be crossed.
In some embodiments, the base 1 comprises a bottom plate 11 and two slide rails 12 located on the bottom plate 11;
the sample adding needle module comprises a sliding seat 2 and a sample adding needle 3 arranged on the sliding seat 2, and a sliding groove 21 matched with the sliding rail 12 is arranged on the bottom surface of the sliding seat 2;
sample adding needle 3 is including the needle cap portion 31, needle handle portion 32, thick needle portion 33 and the thin needle portion 34 that connect in order, thin needle portion 34 with thick needle portion 33 is all pegged graft and is fixed in adapter 37, needle cap portion 31, needle handle portion 32 and thick needle portion 33 body structure connect in order, needle handle portion 32 with be equipped with baffle portion 38 between the thick needle portion 33, the last joint of needle handle portion 32 has separation blade 35.
The thick needle part 33 is inserted into the insertion hole 22 of the sliding base 2 and can move relative to the insertion hole 22, that is, the sliding base 2 is located between the adapter 37 and the baffle part 38; a spring 36 is sleeved on the periphery of the thick needle part 33, and the spring 36 is positioned between the sliding seat 2 and the adapter 37; in a normal state, one end surface of the carriage 2 abuts against the spring 36 and the other end surface abuts against the stopper portion 38 by the spring 36.
In some embodiments, the transmission member 4 comprises a driving shaft 41, a driven shaft 42 and a belt 43, and the driving member drives the driving shaft 41 to rotate;
the connecting piece 5 is a sheet metal rib pressing piece and a bolt 52, the belt 43 is positioned between the lower part of the sheet metal pressing piece 51 and the sliding seat 2, and the bolt 52 fixes the upper part of the sheet metal pressing piece 51 on the sliding seat 2, so that the belt 43 is fixedly clamped between the sheet metal pressing piece 51 and the sliding seat 2.
That is, the driving member of this embodiment changes the rotational motion into a linear motion through the transmission rod of the belt 43, the belt 43 has a long length, and the sample injection needle module can move along with the belt 43 within a half of the length of the belt 43, so that the degree of freedom of the use of the sample injection needle 3 module is increased; and the cost of the belt 43 is lower than that of the lead screw structure, and the tolerance is strong.
In some embodiments, the drive member is a motor 6, and preferably a servo motor 6.
In some embodiments, to facilitate the mounting and dismounting of the loading needle 3, the slide base 2 is a block structure, and a concave loading needle mounting platform 23 is disposed at one corner of the slide base.
In some embodiments, in order to obtain the distance between the sample application needle 3 and the liquid sample to be tested in the test tube, so that the controller controls the motor 6 to drive the sample application needle 3 to enter the liquid sample to be tested, a liquid level detector 7 is further provided, the liquid level detector 7 is mounted on the upper surface of the sliding base 2, the liquid level detector 7 is a micro liquid level detection sensor, and the sensor model is WTLLS-485B.
In some embodiments, in order to control the stroke of the sampling needle 3, a bottom contact detector 8 is further provided, the bottom contact detector 8 is a TP805 groove-shaped optocoupler and is installed on the side wall of the sampling needle installation table 23, and a separation blade 35 is clamped at the piston rod part of the sampling needle 3. After 34 tip contact test tube bottoms of thin needle portion of application of sample needle 3, motor 6 continues to drive slide 2 and removes to the direction of being close to the test tube bottom, compression spring 36, and then reverse-thrust application of sample needle 3 removes to opposite direction, in case the separation blade 35 of joint is located the cell type opto-coupler in on application of sample needle 3, the cell type opto-coupler transmits signal to the controller, 6 antiport of controller control motor, motor 6 drives slide 2 and application of sample needle 3 and sets for the stroke distance to the direction motion of keeping away from the test tube bottom promptly, spring 36 rebounds simultaneously, should set for the setting of stroke distance, mainly for letting thin needle portion 34 tip and test tube bottom leave the clearance, so that the imbibition operation.
While one embodiment of the present invention has been described in detail, the description is only a preferred embodiment of the present invention and should not be taken as limiting the scope of the invention. All equivalent changes and modifications made within the scope of the present invention shall fall within the scope of the present invention.

Claims (10)

1. The multi-needle linear module for the chemiluminescence instrument is characterized by comprising a driving piece, a connecting piece, a base and sampling needle modules, wherein at least two independent sampling needle modules are arranged on the base side by side;
the base comprises a bottom plate and at least two sliding rails positioned on the bottom plate;
the sample adding needle module comprises a sliding seat and a sample adding needle arranged on the sliding seat, and a sliding groove matched with the sliding rail is arranged on the bottom surface of the sliding seat;
the transmission part is a belt driven by the driving part to move.
2. The multi-needle linear module for a chemiluminescent instrument of claim 1 wherein the driving member further comprises a driving shaft and a driven shaft wrapped by a belt, the driving member driving the driving shaft to rotate.
3. The multi-needle linear module of claim 1, wherein the sample injection needle comprises a needle cap portion, a needle handle portion, a thick needle portion and a thin needle portion, which are connected in sequence, the thin needle portion and the thick needle portion are fixed in the adapter in an inserting manner, the needle cap portion, the needle handle portion and the thick needle portion are connected in sequence, and a baffle portion is arranged between the needle handle portion and the thick needle portion.
4. The multi-pin linear module of claim 3, wherein the thick pin is inserted into the insertion hole of the slide base and is movable relative to the insertion hole; the sliding seat is positioned between the adapter and the baffle part; a spring is sleeved on the periphery of the thick needle part and is positioned between the sliding seat and the adapter; under the action of the spring, one end face of the sliding seat is abutted against the spring, and the other end face of the sliding seat is abutted against the baffle plate part.
5. The multi-needle linear module for a chemiluminescent instrument of claim 3 wherein the needle handle is snap fit with a catch.
6. The multi-pin linear module for a chemiluminescent instrument of claim 1 wherein the carriage is a block structure having a recessed loading pin mounting platform.
7. The multi-pin linear module for a chemiluminescent instrument of claim 1 wherein the connector is a web press and a bolt, the belt is located between the lower portion of the sheet metal press and the slide, and the bolt secures the upper portion of the sheet metal press to the slide.
8. The multi-pin linear module for a chemiluminescent instrument of claim 1 further comprising a level detector mounted on the upper surface of the carriage.
9. The multi-pin linear module for chemiluminescent instrument of claim 1 further comprising a bottom contact detector mounted on the sidewall of the sample addition pin mounting platform.
10. The multi-pin linear die set for a chemiluminescent instrument of claim 1 wherein the drive member is a motor.
CN202010306318.8A 2020-04-17 2020-04-17 Multi-needle linear module for chemiluminescence apparatus Pending CN111351953A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010306318.8A CN111351953A (en) 2020-04-17 2020-04-17 Multi-needle linear module for chemiluminescence apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010306318.8A CN111351953A (en) 2020-04-17 2020-04-17 Multi-needle linear module for chemiluminescence apparatus

Publications (1)

Publication Number Publication Date
CN111351953A true CN111351953A (en) 2020-06-30

Family

ID=71193499

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010306318.8A Pending CN111351953A (en) 2020-04-17 2020-04-17 Multi-needle linear module for chemiluminescence apparatus

Country Status (1)

Country Link
CN (1) CN111351953A (en)

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