CN111346166A - Wet tissue for relieving insufficient tear secretion and preparation method thereof - Google Patents
Wet tissue for relieving insufficient tear secretion and preparation method thereof Download PDFInfo
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- CN111346166A CN111346166A CN201811580187.1A CN201811580187A CN111346166A CN 111346166 A CN111346166 A CN 111346166A CN 201811580187 A CN201811580187 A CN 201811580187A CN 111346166 A CN111346166 A CN 111346166A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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Abstract
The invention discloses a wet tissue for relieving insufficient tear secretion and a preparation method thereof. The wet tissue liquid part is prepared from the following raw materials in parts by weight: 10-20 parts of prepared rhizome of rehmannia, 10-20 parts of medlar, 5-15 parts of chrysanthemum, 7-17 parts of dogwood, 7-17 parts of yam, 5-15 parts of tuckahoe and 10-20 parts of butterflybush flower. The traditional Chinese medicine wet tissue provided by the invention can relieve insufficient tear secretion, tonify liver and kidney, nourish blood and improve eyesight, has obvious curative effects on relieving eye fatigue, dryness, swelling, blurred vision and other symptoms, and has important application value.
Description
Technical Field
The invention relates to a wet tissue and a preparation method thereof, in particular to a wet tissue for relieving insufficient tear secretion and a preparation method thereof.
Background
The wet tissue has the effects of skin care, moistening and the like and is convenient to carry, so that the wet tissue is widely applied to daily life of people. Some people require the use of wet wipes to clean the skin of the eyes or to provide wet relief to dry eyes, and some known wet wipes are often irritating to the eyes.
Therefore, it is desirable to provide a non-irritating, moisture-retaining, non-greasy wet wipe that also alleviates the symptoms of dry eye due to insufficient tear secretion, and eliminates the symptoms of asthenopia, redness, foreign body sensation, itching, and the like.
Disclosure of Invention
The invention aims to provide a wet tissue for relieving insufficient tear secretion and a preparation method thereof.
The eye-protecting liquid medicine provided by the invention is prepared from the following raw materials in parts by weight: 10-20 parts of prepared rhizome of rehmannia, 10-20 parts of medlar, 5-15 parts of chrysanthemum, 7-17 parts of dogwood, 7-17 parts of yam, 5-15 parts of tuckahoe and 10-20 parts of butterflybush flower.
The traditional Chinese medicine wet tissue capable of relieving insufficient tear secretion provided by the invention is characterized in that the liquid part is prepared from the following raw materials in parts by weight:
10-20 parts of prepared rhizome of rehmannia, 10-20 parts of medlar, 5-15 parts of chrysanthemum, 7-17 parts of dogwood, 7-17 parts of yam, 5-15 parts of tuckahoe and 10-20 parts of butterflybush flower.
In the eye protection liquid medicine or the traditional Chinese medicine wet tissue, the components are as follows in parts by weight: 15 parts of prepared rhizome of rehmannia, 15 parts of medlar, 10 parts of chrysanthemum, 12 parts of dogwood, 12 parts of yam, 10 parts of tuckahoe and 15 parts of butterflybush flower.
The raw materials also comprise the following auxiliary materials in parts by weight:
1-5 parts of borneol, 15-25 parts of ethanol water solution and 600 parts of water 400-.
Specifically, the auxiliary materials comprise the following components in parts by weight: 2 parts of borneol, 20 parts of ethanol water solution and 500 parts of water;
in the ethanol water solution, the mass percentage concentration of ethanol is 75% +/-5%.
The method for preparing the eye protection liquid medicine or the traditional Chinese medicine wet tissue comprises the following steps;
1) soaking the raw materials in water according to the proportion;
2) boiling the raw materials in water, decocting, and cooling to obtain a liquid medicine I;
3) dissolving borneol in 75% +/-5% ethanol, and adding the solution into the solution I to obtain the eye-protecting solution;
soaking the non-woven fabrics in the eye protection liquid medicine, taking out, bagging and sealing to obtain the traditional Chinese medicine wet tissue;
the total amount of the water used in the soaking step 1) and the water used in the boiling and decocting step 2) is the weight part of the water.
In the soaking step in the step 1) of the method, the time is 25-35 min; specifically 30 min; the temperature is 15-25 ℃; in particular 20 ℃;
in the step 2), the decoction time is 25-35 min; specifically 30 minutes; the decoction is carried out by slow fire.
The decoction with slow fire is carried out to ensure that the liquid medicine keeps a slightly boiling state all the time.
In addition, the eye protection liquid medicine or the traditional Chinese medicine eye patch provided by the invention is applied to preparing a product for preventing and treating myopia. And the application in preventing and treating myopia, which also belongs to the protection scope of the invention.
The use method of the traditional Chinese medicine wet tissue is to wipe the periphery of eyes. The swab can be gently wiped 5-10 times as required.
The traditional Chinese medicine wet tissue provided by the invention can relieve insufficient tear secretion, tonify liver and kidney, nourish blood and improve eyesight, has obvious curative effects on relieving eye fatigue, dryness, swelling, blurred vision and other symptoms, and has important application value.
Detailed Description
The present invention will be further illustrated with reference to the following specific examples, but the present invention is not limited to the following examples. The method is a conventional method unless otherwise specified. The starting materials are commercially available from the open literature unless otherwise specified. The parts described in the following examples are all parts by mass unless otherwise specified. The Chinese medicinal materials used in the following examples were purchased from Beijing Hoorentang drugstore.
Example 1
The liquid part of the traditional Chinese medicine wet tissue is prepared from the following raw materials in parts by weight: 15 parts of prepared rhizome of rehmannia, 15 parts of medlar, 10 parts of chrysanthemum, 12 parts of dogwood, 12 parts of yam, 10 parts of tuckahoe and 15 parts of butterflybush flower. According to the proportion, the wet tissue provided by the invention can tonify liver and kidney, nourish blood and improve eyesight.
Auxiliary materials: 2 parts of borneol, 20 parts of ethanol water solution with the mass percentage concentration of 75 +/-5 percent and 500 parts of purified water. The amount of purified water is the total amount of water used in the soaking, boiling and decocting steps of the method.
The preparation method of the traditional Chinese medicine wet tissue comprises the following steps:
soaking the traditional Chinese medicines in cold water for 30min before decocting, adding the 15 parts of radix rehmanniae Preparata, 15 parts of fructus Lycii, 10 parts of flos Chrysanthemi, 12 parts of Corni fructus, 12 parts of rhizoma Dioscoreae, 10 parts of Poria and 15 parts of flos Buddlejae into purified water, heating to boil, decocting with slow fire for 30min, cooling, and filtering to obtain traditional Chinese medicine liquid; dissolving Borneolum Syntheticum with ethanol, adding the Chinese medicinal liquid, and filtering to obtain eye protecting liquid; and soaking the non-woven fabrics in the eye protection liquid medicine, and putting the non-woven fabrics into a bag for sealing after the non-woven fabrics are fully absorbed to obtain the traditional Chinese medicine wet tissue.
The efficacy of the wet tissue of the traditional Chinese medicine obtained in example 1 of the present invention is further demonstrated by the efficacy test.
In the test, 12 volunteers lightly wipe the periphery of eyes 5-10 times by using the wet tissue.
Symptoms are: all 12 volunteers had eye sensitivity to external stimuli, photophobia, aversion to wind, viscous secretion, foreign body sensation, itching, dryness, congestion, and red swelling.
The curative effect standard is as follows: the volunteer complaints were used to determine the extent of relief (effective, ineffective) and the feeling of the symptoms after wiping.
Wherein, the judgment criteria of the effect, the effectiveness and the ineffectiveness are as follows:
the effect is shown: after being wiped, the eye feels cool, the circumference of the eye is comfortable, and the eyes are bright;
the method has the following advantages: after being wiped, the eye mask feels cool and is comfortable around eyes;
and (4) invalidation: the eyes do not feel cool after being wiped, and no obvious feeling is generated around the eyes;
the results are shown in Table 1;
TABLE 1 curative effect of volunteers using wet wipes obtained in example 1 of the present invention
| Volunteer numbering | Post-wipe relief capability | Feeling |
| 1 | Is effective | Cool and comfortable around the eyes |
| 2 | Is effective | Cool and comfortable around the eyes |
| 3 | Is effective | Cool, comfortable around the eyes and bright eyes |
| 4 | Is effective | Has slight medicinal taste, is cool and comfortable around eyes |
| 5 | Is effective | Cool and comfortable around the eyes |
| 6 | Is effective | Cool and comfortable around the eyes |
| 7 | Is effective | Has slight medicinal taste, is cool and comfortable around eyes |
| 8 | Is effective | Cool and comfortable around the eyes |
| 9 | Is effective | Cool and comfortable around the eyes |
| 10 | Is obvious | Cool, comfortable around the eyes and bright eyes |
| 11 | Is effective | Cool and comfortable around the eyes |
| 12 | Is effective | Cool and comfortable around the eyes |
As can be seen from Table 1, the total effective rate of the wet tissue provided by the invention for relieving eye fatigue, dryness, swelling, blurred vision and other symptoms is 100%, wherein the feeling effect after 1 case of use is obvious.
Claims (9)
1. An eye protection liquid medicine is prepared from the following raw materials in parts by weight: 10-20 parts of prepared rhizome of rehmannia, 10-20 parts of medlar, 5-15 parts of chrysanthemum, 7-17 parts of dogwood, 7-17 parts of yam, 5-15 parts of tuckahoe and 10-20 parts of butterflybush flower.
2. A traditional Chinese medicine wet tissue capable of relieving insufficient tear secretion is provided, wherein a liquid part is prepared from the following raw materials in parts by weight:
10-20 parts of prepared rhizome of rehmannia, 10-20 parts of medlar, 5-15 parts of chrysanthemum, 7-17 parts of dogwood, 7-17 parts of yam, 5-15 parts of tuckahoe and 10-20 parts of butterflybush flower.
3. The eye-protecting liquid medicine according to claim 1 or the traditional Chinese medicine wet wipe according to claim 2, which is characterized in that: the weight parts of the components are as follows: 15 parts of prepared rhizome of rehmannia, 15 parts of medlar, 10 parts of chrysanthemum, 12 parts of dogwood, 12 parts of yam, 10 parts of tuckahoe and 15 parts of butterflybush flower.
4. The eye-protecting liquid medicine or traditional Chinese medicine wet wipe according to any one of claims 1 to 3, characterized in that: the raw materials also comprise the following auxiliary materials in parts by weight:
1-5 parts of borneol, 15-25 parts of ethanol water solution and 600 parts of water 400-.
5. The eye-protecting liquid medicine or traditional Chinese medicine wet wipe according to claim 4, characterized in that: the auxiliary materials comprise the following components in parts by weight: 2 parts of borneol, 20 parts of ethanol water solution and 500 parts of water;
in the ethanol water solution, the mass percentage concentration of ethanol is 75% +/-5%.
6. A method for preparing the eye-protecting liquid medicine or the traditional Chinese medicine wet tissue of any one of claims 1 to 5, comprising;
1) soaking the raw materials in water according to the proportion;
2) boiling the raw materials in water, decocting, and cooling to obtain a liquid medicine I;
3) dissolving borneol in 75% +/-5% ethanol, and adding the solution into the solution I to obtain the eye-protecting solution;
soaking the non-woven fabrics in the eye protection liquid medicine, taking out, bagging and sealing to obtain the traditional Chinese medicine wet tissue;
the total amount of the water used for the soaking in the step 1) and the water used for the boiling and decocting in the step 2) is the weight part of the water in the claim 4 or 5.
7. The method of claim 6, wherein: in the step 1), the soaking time is 25-35 min; specifically 30 min; the temperature is 15-25 ℃; in particular 20 ℃;
in the step 2), the decoction time is 25-35 min; specifically 30 minutes; the decoction is carried out by slow fire.
8. The use of the eye-protecting liquid medicine or the traditional Chinese medicine wet wipe as set forth in any one of claims 1 to 5 for preparing a product for relieving insufficient tear secretion.
9. The use of the eye-protecting liquid or medicated wet wipe of any one of claims 1-5 for the relief of tear hyposecretion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811580187.1A CN111346166A (en) | 2018-12-24 | 2018-12-24 | Wet tissue for relieving insufficient tear secretion and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811580187.1A CN111346166A (en) | 2018-12-24 | 2018-12-24 | Wet tissue for relieving insufficient tear secretion and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN111346166A true CN111346166A (en) | 2020-06-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811580187.1A Pending CN111346166A (en) | 2018-12-24 | 2018-12-24 | Wet tissue for relieving insufficient tear secretion and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118436743A (en) * | 2024-07-05 | 2024-08-06 | 天津益倍元天然产物技术有限公司 | Composition with asthenopia relieving function and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943693A (en) * | 2006-10-17 | 2007-04-11 | 宝鸡市瑞海药业有限责任公司 | Traditional Chinese medicine preparation for eye health care and asthenopia alleviation |
| CN101708192A (en) * | 2009-12-15 | 2010-05-19 | 广东太安堂制药有限公司 | Method for preparing Chinese medicament pills |
-
2018
- 2018-12-24 CN CN201811580187.1A patent/CN111346166A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943693A (en) * | 2006-10-17 | 2007-04-11 | 宝鸡市瑞海药业有限责任公司 | Traditional Chinese medicine preparation for eye health care and asthenopia alleviation |
| CN101708192A (en) * | 2009-12-15 | 2010-05-19 | 广东太安堂制药有限公司 | Method for preparing Chinese medicament pills |
Non-Patent Citations (3)
| Title |
|---|
| 宗诚,等: "辨证论治干眼症72例", 《山东中医杂志》 * |
| 张笑吟,等: "中西医结合治疗肝肾阴虚型干眼症临床观察", 《光明中医》 * |
| 蒋培华,等: "中药新剂型——口服液剂", 《上海中医药杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118436743A (en) * | 2024-07-05 | 2024-08-06 | 天津益倍元天然产物技术有限公司 | Composition with asthenopia relieving function and preparation method and application thereof |
| CN118436743B (en) * | 2024-07-05 | 2024-09-03 | 天津益倍元天然产物技术有限公司 | Composition with asthenopia relieving function and preparation method and application thereof |
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Application publication date: 20200630 |