CN111329612A - Rat crush injury mold and crush injury experimental method - Google Patents
Rat crush injury mold and crush injury experimental method Download PDFInfo
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- CN111329612A CN111329612A CN202010194195.3A CN202010194195A CN111329612A CN 111329612 A CN111329612 A CN 111329612A CN 202010194195 A CN202010194195 A CN 202010194195A CN 111329612 A CN111329612 A CN 111329612A
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- 208000025962 Crush injury Diseases 0.000 title claims abstract description 52
- 238000002474 experimental method Methods 0.000 title claims abstract description 13
- 241000700159 Rattus Species 0.000 claims abstract description 128
- 238000001125 extrusion Methods 0.000 claims abstract description 94
- 230000007246 mechanism Effects 0.000 claims abstract description 82
- 238000003780 insertion Methods 0.000 claims description 11
- 230000037431 insertion Effects 0.000 claims description 11
- 230000000149 penetrating effect Effects 0.000 claims description 5
- 238000004088 simulation Methods 0.000 abstract description 2
- 210000002414 leg Anatomy 0.000 description 36
- 230000009471 action Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 238000002224 dissection Methods 0.000 description 3
- 210000003484 anatomy Anatomy 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- FGRBYDKOBBBPOI-UHFFFAOYSA-N 10,10-dioxo-2-[4-(N-phenylanilino)phenyl]thioxanthen-9-one Chemical compound O=C1c2ccccc2S(=O)(=O)c2ccc(cc12)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 FGRBYDKOBBBPOI-UHFFFAOYSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 210000000078 claw Anatomy 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Husbandry (AREA)
- Surgery (AREA)
- Catching Or Destruction (AREA)
Abstract
The invention provides a rat crush injury mould and a crush injury experimental method, belonging to the technical field of simulation crush injury, wherein the rat crush injury mould comprises: base, fixed subassembly, support frame, a plurality of extrusion mechanism and rotation piece. The top of the slide rail is provided with a clamping groove in a run-through way. A plurality of extrusion mechanism covers are established and are slided and set up on the slide rail, and extrusion mechanism's bottom is provided with the extruded article, and the extruded article is used for extrudeing the shank of rat. The rotating piece penetrates through and is in threaded connection with the top of the extrusion mechanism, and the rotating piece is clamped and slidably arranged in the clamping groove. The extrusion mechanism drives the rotating piece to slide along the clamping groove; the extrusion mechanism drives the extrusion piece to move downwards by means of the thread force of the rotating piece, and then the leg of the rat is extruded. A crush injury experimental method adopts the rat crush injury mould. The rat crush injury mould and the crush injury experimental method provided by the invention can adapt to the extrusion of the legs of rats with different sizes, and have strong applicability.
Description
Technical Field
The invention belongs to the technical field of simulation of crush injury, and particularly relates to a rat crush injury mold and a crush injury experimental method adopting the rat crush injury mold.
Background
In the rat experiment, a certain weight is required to be placed on the leg of the rat, and after a preset time is reached, the rat is subjected to a series of researches such as dissection and the like, so that the muscle tissue change of a human body after being squeezed by the weight is analyzed and determined. Due to the fact that the rats are different in size and the positions of the legs are different, the existing extruding upper die cannot be adjusted correspondingly according to the positions of the legs of the rats, and accordingly the applicability is poor.
Disclosure of Invention
The invention aims to provide a rat crush injury mould and a crush injury experimental method, and aims to solve the problems that the crush injury mould cannot be correspondingly adjusted according to the leg of a rat, and is poor in applicability and low in efficiency.
In order to achieve the purpose, the invention adopts the technical scheme that: providing a rat crush injury mold comprising:
the upper surface of the base is provided with an inserting groove;
the fixing component is inserted and positioned on the base and used for fixing a rat;
the bottom of the support frame is detachably connected to the support frame, and the top of the support frame is provided with a slide rail; the top of the sliding rail is provided with a clamping groove in a penetrating way;
the extrusion mechanisms are sleeved and arranged on the sliding rails in a sliding mode, extrusion pieces are arranged at the bottoms of the extrusion mechanisms and are used for extruding the legs of the rats; and
the rotating pieces correspond to the extrusion mechanisms one by one, penetrate through the top of the extrusion mechanisms and are in threaded connection with the top of the extrusion mechanisms, and the rotating pieces are clamped and arranged in the clamping grooves in a sliding mode;
the extrusion mechanism drives the rotating piece to slide along the clamping groove; the extrusion mechanism drives the extrusion piece to move downwards by means of the thread force of the rotating piece, and then the leg of the rat is extruded.
As another embodiment of this application, it is close to rotate the piece the one end of slide rail is fixed with the spacing piece, it drives to rotate the piece the spacing piece rotates and slides and set up the joint inslot.
As another embodiment of the present application, the width of the bottom of the clamping groove is greater than the width of the top; the bottom surface of the clamping groove is an abutting surface, and the abutting surface is parallel to the upper surface of the base.
As another embodiment of the present application, the pressing mechanism includes:
the supporting frame is sleeved on the sliding rail, and the side surface of the inner edge of the supporting frame is in sliding fit with the sliding rail; the top surface and the bottom surface of the inner edge of the supporting frame are both arranged at a certain distance from the sliding rail; the top of the supporting frame is in threaded connection with the rotating piece; and
the extruded article is connected the bottom of carriage, the extruded article is kept away from the reducing groove has been seted up to one side of slide rail, the extruded article with the help of the reducing groove is fixed and is extruded the shank of rat.
As another embodiment of the present application, the extrusion is connected to a bottom bulb of the support frame.
As another embodiment of this application, the fixed slot has been seted up on the base, be fixed with the fixed part on the lateral wall of fixed slot, the fixed part with another lateral wall interval of fixed slot sets up at a certain distance, the fixed part is used for spacingly the support frame.
As another embodiment of the present application, the insertion groove is disposed along an outer edge of the base; the inserting groove is used for inserting and positioning the outer edges of the two sides of the fixing component.
As another embodiment of the present application, the fixing assembly includes:
the fixing frame is of a hollow structure and is inserted into the insertion groove; a plurality of fixing rings are fixed on the inner wall of the fixing frame; the outer edges of the two sides of the fixing frame are respectively used for being plugged and limited with the plugging grooves; and is abutted against the bottom of the inserting groove; and
the fixing pieces correspond to the fixing rings one by one; one end is connected on the fixed ring, and the other end is used for being connected with the leg of the rat.
As another embodiment of the application, an avoiding groove is formed in the inner side surface of the extrusion part, a pressure sensor is fixed in the avoiding groove, and the pressure sensor is used for measuring the extrusion force of the extrusion part on the leg of the rat; a temperature adjusting device is fixed at the bottom of the base; and a temperature display is arranged on the upper surface of the base.
The rat crush injury mould has the beneficial effects that compared with the prior art, the rat crush injury mould firstly fixes the rat on the fixing component, and the fixing component is inserted and positioned on the base due to the insertion groove formed in the base. The rat can relatively keep the position of the leg and the like stable by the action of the fixing component. The bottom of the support frame is detachably connected to the support frame, a slide rail is arranged at the top of the support frame, and a clamping groove is formed in the slide rail in a penetrating mode. The sliding rail is sleeved and slidably provided with an extrusion mechanism, and the bottom of the extrusion mechanism is provided with an extrusion piece used for pressing the legs of a rat. The rotating piece penetrates through and is in threaded connection with the top of the extruding mechanism. The rotating piece is clamped and arranged in the clamping groove in a sliding mode. Because the rotating part is in threaded connection with the extrusion mechanism, the rotating part slides along the sliding groove when the extrusion mechanism slides along the sliding rail. After the extrusion mechanism slides to the designated position, the corresponding rotating part is rotated to drive the extrusion piece to move downwards by the extrusion mechanism, so that the leg of the rat below is extruded. In this application, the position of extrusion mechanism accessible slide rail change for the base to can adapt to the extrusion with the shank of unidimensional rat, the suitability is stronger.
The invention also aims to provide a crush injury experimental method, which comprises the following steps:
fixing a rat on a fixing component, and inserting and limiting one side edge of the fixing component on a base;
adjusting the position of the extrusion mechanism relative to the support frame according to the overall dimension of the rat, and detachably connecting the support frame to the base;
the rotating part in threaded connection with the squeezing mechanism is rotated to enable the squeezing mechanism to squeeze the leg of the rat;
after a preset requirement is met, disassembling the support frame and the extrusion mechanism;
and taking out the fixed component, overturning the fixed component, inserting and limiting the other side edge of the fixed component on the base, and dissecting the rat.
Compared with the prior art, the crush injury experimental method has the advantages that the rat is fixed on the fixing component, and one side edge of the fixing component is inserted and limited on the base. And adjusting the position of the extrusion mechanism relative to the support frame according to the overall dimension of the rat, and detachably connecting the support frame to the base. The leg of the rat is squeezed by the squeezing mechanism by rotating the rotating part in threaded connection with the squeezing mechanism. And after the preset requirements are met, disassembling the support frame and the extrusion mechanism. And taking out the fixed component, overturning the fixed component, inserting and limiting the other side edge of the fixed component on the base, and dissecting the rat. Can reach predetermined pressure and time after the extrusion, after taking off support frame and extrusion mechanism, through the fixed subassembly of upset, can carry out the anatomy to the rat, it is easy and simple to handle, avoided the refastening to the rat, efficiency is higher.
Drawings
FIG. 1 is a schematic structural diagram of a rat crush injury mold according to an embodiment of the present invention;
FIG. 2 is a schematic view of a connection between a fixing assembly and a support frame according to an embodiment of the present invention;
fig. 3 is a schematic view illustrating a connection between a support frame and a support frame according to an embodiment of the present invention;
fig. 4 is a schematic view illustrating a connection between a rotating member and a sliding rail according to an embodiment of the present invention;
FIG. 5 is a schematic view of the connection between the insertion slot and the supporting frame according to the embodiment of the present invention;
fig. 6 is a flowchart of a crush injury testing method according to an embodiment of the present invention.
In the figure: 1. a base; 2. a fixing assembly; 3. a support frame; 4. a clamping groove; 5. an extrusion mechanism; 501. a support frame; 502. an extrusion; 6. a rotating member; 7. a slide rail; 8. a limiting member; 9. a fixing ring; 10. a temperature adjustment device; 11. a fixing member; 12. a temperature display; 13. a display screen; 14. a ball head connecting piece; 15. a pressure sensor; 16. inserting grooves; 17. a fixed part; 18. fixing grooves; 19. a plug-in part; 20. a sliding groove; 21. and a positioning pin.
Detailed Description
In order to make the technical problems, technical solutions and advantageous effects to be solved by the present invention more clearly apparent, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Referring to fig. 1 and 2, the rat crush injury mold provided by the present invention will now be described. Rat crush injury mould, including: the device comprises a base 1, a fixed component 2, a support frame 3, a plurality of squeezing mechanisms 5 and a rotating piece 6. The upper surface of the base 1 is provided with an inserting groove 16. The fixed component 2 is inserted and positioned on the base 1, and the fixed component 2 is used for fixing a rat. The bottom of the support frame 3 is detachably connected to the support frame 3, and the top of the support frame 3 is provided with a slide rail 7; the top of the slide rail 7 is provided with a clamping groove 4 in a penetrating way. A plurality of extrusion mechanisms 5 are sleeved and slidably arranged on the slide rail 7, the bottom of the extrusion mechanism 5 is provided with an extrusion piece 502, and the extrusion piece 502 is used for extruding the legs of the rat. Rotate piece 6 and extrusion mechanism 5 one-to-one, run through and threaded connection at extrusion mechanism 5's top, rotate 6 joint and slide and set up in joint groove 4. The extrusion mechanism 5 drives the rotating piece 6 to slide along the clamping groove 4; the pressing mechanism 5 drives the pressing member 502 to move downward by means of the screw force with the rotating member 6, thereby pressing the leg of the rat.
The rat crush injury mould has the beneficial effects that compared with the prior art, the rat crush injury mould firstly fixes the rat on the fixing component 2, and the fixing component 2 is inserted and positioned on the base 1 due to the insertion groove 16 formed on the base 1. The rat can relatively keep the position of the leg and the like stable by the action of the fixing component 2. The bottom of support frame 3 can be dismantled and connect on support frame 3, and the top of support frame 3 is provided with slide rail 7, link up on slide rail 7 and has seted up joint groove 4. The sliding rail 7 is sleeved and slidably provided with an extrusion mechanism 5, and the bottom of the extrusion mechanism 5 is provided with an extrusion piece 502 for compressing the leg of the rat. The rotating member 6 penetrates and is screwed on the top of the pressing mechanism 5. The rotating piece 6 is clamped and arranged in the clamping groove 4 in a sliding mode. Since the rotating member 6 is threadedly coupled to the pressing mechanism 5, the rotating member 6 slides along the sliding groove while the pressing mechanism 5 slides along the sliding rail 7. After the pressing mechanism 5 slides to a designated position, the corresponding rotating member 6 is rotated to make the pressing mechanism 5 drive the pressing member 502 to move downwards, thereby pressing the leg of the rat below. In this application, extrusion mechanism 5 accessible slide rail 7 changes the position for base 1 to can adapt to the extrusion with the shank of unidimensional rat, the suitability is stronger.
As a specific embodiment of the rat crush injury mold provided by the present invention, please refer to fig. 4, a limiting member 8 is fixed at one end of the rotating member 6 close to the sliding rail 7, and the rotating member 6 drives the limiting member 8 to rotate and to be slidably disposed in the clamping groove 4. The locating part 8 joint is in joint inslot 4 to locating part 8 can make the effort that rotates piece 6 and slide rail 7 through setting up locating part 8 by rotating the piece 6 at the joint inslot 4 internal rotation under driving about, can act on extruded article 502.
As a specific embodiment of the rat crush injury mold provided by the present invention, please refer to fig. 3, the width of the bottom of the clamping groove 4 is greater than the width of the top; one end of the rotating piece 6 close to the clamping groove 4 rotates and is arranged in the clamping groove 4 in a sliding mode. The clamping groove 4 is arranged at the top of the sliding rail 7 in a penetrating mode, the clamping groove 4 is a closing groove, and the section of the clamping groove 4 decreases progressively from bottom to top. After rotating piece 6 and sliding into joint groove 4, joint groove 4 can prevent to rotate piece 6 from the top slippage of slide rail 7. The rotating piece 6 slides near one end of the sliding rail 7 and can rotate in the clamping groove 4. When the corresponding rotating member 6 is rotated, the rotating member 6 pushes the sliding rail 7 downwards, and the pressing mechanism 5 moves downwards under the action of the rotating member 6, so as to drive the bottom pressing member 502 to press the leg of the rat.
As a specific embodiment of the rat crush injury mold provided by the present invention, please refer to fig. 4, the slide rail 7 is a polygonal prism structure, the bottom surface of the clamping groove 4 is an abutting surface, and the abutting surface is parallel to the upper surface of the base 1. The squeezing mechanism 5 is slidably arranged on the slide rail 7, and in order to prevent the squeezing mechanism 5 from swinging around the axis of the slide rail 7, the slide rail 7 is of a polygonal prism structure. The inner edge of the extrusion mechanism 5 is provided with a limit groove, and the side surface of the limit groove is attached to the slide rail 7. The upper and lower both sides face and the slide rail 7 interval certain distance setting of spacing groove, rotate piece 6 and run through and threaded connection on extrusion mechanism 5, the tip that rotates piece 6 passes the clearance between spacing groove and the slide rail 7 and the butt on slide rail 7 to the tip that rotates piece 6 slides and the joint is in joint inslot 4. When pressing is required, the corresponding rotary part 6 is rotated and the pressing mechanism 5 is moved downwards. The top surface of the slide rail 7 is an abutting surface, and the abutting surface is a plane parallel to the base 1 in order to ensure the abutting surface to be closely contacted with the rotating member 6. The locating part 8 butt is on the plane to the perpendicular slide rail 7 setting of locating part 8, thereby guarantee when rotating 6 rotations, locating part 8 can be stabilized at 4 rotations of joint inslot.
Referring to fig. 4, as a specific embodiment of the rat crush injury mold provided in the present invention, the squeezing mechanism 5 includes: a support frame 501 and an extrusion 502. The supporting frame 501 is sleeved on the slide rail 7, and the side surface of the inner edge of the supporting frame 501 is in sliding fit with the slide rail 7; the top surface and the bottom surface of the inner edge of the supporting frame 501 are both arranged at a certain distance from the slide rail 7; the top of the support frame 501 is screwed with the rotation member 6. The bottom at the carriage 501 is connected to extruded article 502, and the reducing groove has been seted up to extruded article 502 one side of keeping away from slide rail 7, and extruded article 502 fixes and extrudees the shank of rat with the help of the reducing groove. Since rats vary in size, the pressing mechanism 5 is slidably disposed on the slide rail 7, so that the position of the pressing member 502 can be changed according to the applicability of a specific rat structure. The sliding sleeve of the pressing frame is arranged on the sliding rail 7, the side face of the inner edge of the pressing frame is attached to the side face of the sliding rail 7, and the top and the bottom of the inner edge of the pressing frame are arranged at intervals of a certain distance from the upper surface and the lower surface corresponding to the sliding rail 7, so that an adjusting space is reserved for the rotating piece 6. The bottom of the support frame 501 is connected with a pressing member 502. When the support frame 501 rotates, the extrusion member 502 rotates, and drives the extrusion member 502 to downwards extrude the leg of the rat. Because the cross-section of the leg of the rat is gradually reduced from the middle part to the claw part, the end part of the extrusion piece 502 far away from the sliding rail 7 is provided with a reducing groove, and the reducing groove comprises a large-diameter end and a small-diameter end. The minor diameter end and the major diameter end are arranged at the same height and arranged along the width direction of the base 1. The small diameter end is arranged close to the outer edge of the base 1 relative to the large diameter end. The force of the pressing mechanism 5 caused by the pressing member 502 can be applied approximately uniformly to the legs of the rat by the pressing member 502, and concentration of pressure on the legs is avoided. Since the muscles of the rat's thigh are developed, the rat's leg is usually compressed only when the compression injury is made. The number of the supporting frames 3 can be one, and two squeezing mechanisms 5 and two rotating parts 6 corresponding to each other are fixed on the supporting frames 3. The two rotary members 6 are independent of each other so as to be able to adjust the pressure of the different squeezing mechanisms 5 on the rat's leg.
Referring to fig. 3, an extrusion member 502 is connected to a bottom ball of a supporting frame 501. Due to the different sizes of the rat structures, the leg parts of the rats are inevitably dislocated in the compression process. A ball head connecting piece 14 is arranged between the bottom of the supporting frame and the extrusion piece, one end of the ball head connecting piece 14 is fixed at the bottom of the supporting frame, and the other end of the ball head connecting piece is connected with the extrusion piece. In order to stably apply pressure to the legs of the rat, the extrusion piece 502 is connected with the ball head of the extrusion mechanism 5, the extrusion piece 502 can be adjusted to a position corresponding to the legs of the rat through the ball head connection, and the phenomenon that the legs of the rat are extruded by the local part of the extrusion piece 502 to cause the excessive concentration of the local pressure of the rat is avoided.
As a specific embodiment of the rat crush injury mold provided by the present invention, please refer to fig. 5, a fixing groove 18 is formed on a base 1, a fixing portion 17 is fixed on one side wall of the fixing groove 18, the fixing portion 17 is spaced from another side wall of the fixing groove 18 by a certain distance, and the fixing portion 17 is used for limiting a supporting frame 3. A fixing portion 17 is fixed on one side wall of the fixing groove 18, the fixing portion 17 is spaced from the other side wall of the fixing groove 18 by a certain distance and is used for yielding the support frame 3, and the fixing portion 17 is used for positioning the support frame 3. A fixing groove 18 is formed on the upper surface of the base 1, a fixing portion 17 is formed on one side wall of the fixing groove 18, and the fixing portion 17 is spaced apart from the other side wall of the fixing groove 18 by a predetermined distance. The distance of the fixing part 17 close to the other side wall of the fixing groove 18 is larger than the width of the bottom of the support frame 3, and the support frame 3 can be inserted into the fixing groove 18 and is clamped on the fixing part 17. In order to ensure ease and effectiveness of disassembly. The bottom of the support frame 3 is fixed with a plug-in part 19, and the thickness of the plug-in part 19 is the same as the height of the fixing part 17 from the bottom of the fixing groove 18. Meanwhile, the distance between the side surface of the fixing part 17 and the fixing groove 18 is larger than the length of the connecting plug part 19 of the support frame 3. Thereby ensuring that the support frame 3 and the inserting part 19 can be inserted into the fixing groove 18 and limiting the inserting part 19 on the fixing part 17. When the support frame 3 needs to be disassembled, the support frame 3 can be reversely slid out. The quantity of fixed slot 18 and the bottom one-to-one setting of support frame 3 to in order to guarantee the stability of support frame 3 position, be fixed with the rib in the bottom of support frame 3, the rib is certain angle setting with support frame 3, and set up the spacing groove fixed with the rib grafting equally on base 1, through the intercommunication effect of support frame 3 and rib, make support frame 3 can the stable positioning on base 1. The top of the base 1 is provided with a sliding groove 20 for the support frame 3 to slide, and the support frame 3 can slide along the sliding groove 20 along the side edge of the base 1, so that the applicability of the device is improved. And have link up in the direction of height along support frame 3 and seted up threaded connection hole, threaded connection has locating pin 21 in the threaded connection hole, slides prop up quick-witted 3 and arrive the assigned position after, can fix support frame 3 on base 1 through rotating locating pin 21.
As a specific embodiment of the rat crush injury mold provided by the present invention, please refer to fig. 2, the insertion groove 16 is disposed along the outer edge of the base 1; the inserting groove 16 is used for inserting and positioning the outer edges of the two sides of the fixing component 2; the fixed slot 18 has been seted up on base 1, because when the experiment was hindered to rat extrusion, the rat was square to be fixed on base 1 to and laminate the inboard of rat on base 1 through fixed subassembly 2, the extruded back that is the shank of rat of extruded 502. After the crush injury is completed, the rat needs to be dissected, and the rat needs to be turned over during dissection, so that the back of the rat is attached to the base 1, and the abdomen and other positions are exposed. Since the rat's fixation is separated from the compression structure in this application. That is, the fixing component 2 is only used for fixing the rat, and the supporting frame 3 and the squeezing mechanism 5 are used for squeezing the rat. Therefore, after the pressing time and the pressing force reach the preset requirements, the pressing mechanism 5 is detached from the base 1. The fixing member 2 is removed and the fixing member 2 is turned over and then inserted into the insertion groove 16 again. Therefore, the rat can be directly dissected without re-fixation, the efficiency is improved, and the rat can be immediately dissected after extrusion is finished, so that the timeliness is guaranteed.
Referring to fig. 4, as a specific embodiment of the rat crush injury mold provided in the present invention, the fixing member 2 includes: a fixed frame and a plurality of fixing members 11. The fixing frame is of a hollow structure and is inserted in the insertion groove 16; a plurality of fixing rings 9 are fixed on the inner wall of the fixing frame; the outer edges of the two sides of the fixing frame are respectively used for being plugged and limited with the plugging groove 16; and abuts against the bottom of the insertion slot 16. The plurality of fixing pieces 11 correspond to the fixing rings 9 one by one; one end is connected to the fixing ring 9 and the other end is used for connecting with the leg of the rat. The fixing frame is a hollow frame body, and the wall body of the fixing frame is rigid and thin. The wall of the retaining frame can be plugged into the plug-in slot 16 and can be pushed into contact with the plug-in slot 16, i.e. the base 1. The structure of fixed frame is along the outer edge setting of base 1, is fixed with a plurality of solid fixed rings 9 on the inner wall of fixed frame, gu fixed ring 9 is last one-to-one to be connected with mounting 11, mounting 11 can be for fixed rope or for the flexible rope that has certain elasticity performance. One end of the fixing part 11 is connected to the fixing ring 9, the other end of the fixing part is used for fixing the fixing part of the corresponding rat, and the four limbs of the rat can be spread on the base 1 through the fixing ring 9 and the fixing part 11. The rat follows fixed frame and base 1 contact, after the extrusion is accomplished, follows fixed frame upset this moment back butt on base 1 to carry out the dissection of next step.
As a specific embodiment of the rat crush injury mold provided by the present invention, please refer to fig. 5, an avoiding groove is formed on an inner side surface of the extrusion piece 502, a pressure sensor 15 is fixed in the avoiding groove, and the pressure sensor 15 is used for measuring the extrusion force of the extrusion piece 502 to the leg of the rat; a temperature adjusting device 10 is fixed at the bottom of the base 1; a temperature display 12 is mounted on the upper surface of the base 1. In order to accurately determine the extrusion strength of the extrusion part 502 to the leg of the rat, an avoiding groove is formed in the inner side face of the extrusion part 502, the pressure sensor 15 is fixed in the avoiding groove and used for extruding the leg of the rat, and therefore the pressure to the leg of the rat is measured. The pressure sensor 15 is electrically connected with a display screen 13, and the display screen 13 is used for displaying the current gram pressure, so that the current pressure value is conveniently recorded, adjusted and recorded. In order to simulate the difference of the rat crush injury in different temperature environments, a temperature adjusting device 10 is fixed at the bottom of the base 1, the temperature adjusting device 10 comprises a heating sheet and a cooling piece, and a temperature display 12 is fixed on the base 1 and displays the current temperature.
Referring to fig. 6, another objective of the present invention is to provide a crush injury testing method, including the following steps:
the rat is fixed on the fixing component 2, and one side of the fixing component 2 is inserted and limited on the base 1.
According to the external dimension of the rat, the position of the extrusion mechanism 5 relative to the support frame 3 is adjusted, and the support frame 3 is detachably connected on the base 1.
The rotating part 6 which is in threaded connection with the squeezing mechanism 5 is rotated to enable the squeezing mechanism 5 to squeeze the leg of the rat;
after the preset requirements are met, the support frame 3 and the extrusion mechanism 5 are disassembled.
Taking out the fixing component 2, overturning the fixing component, inserting and limiting the other side edge of the fixing component 2 on the base 1, and dissecting the rat.
Compared with the prior art, the crush injury experimental method has the advantages that the rat is fixed on the fixing component 2, and one side edge of the fixing component 2 is inserted and limited on the base 1. The position of the extrusion mechanism 5 relative to the support frame 3 is adjusted according to the external dimension of the rat, and the support frame 3 is detachably connected on the base 1. The pressing mechanism 5 presses the leg of the rat by rotating the rotating member 6 screw-coupled with the pressing mechanism 5. After the preset requirements are met, the support frame 3 and the extrusion mechanism 5 are disassembled. Taking out the fixing component 2, overturning the fixing component, inserting and limiting the other side edge of the fixing component 2 on the base 1, and dissecting the rat. Can reach predetermined pressure and time after the extrusion, after taking off support frame 3 and extrusion mechanism 5, through fixed subassembly 2 of upset, can carry out the anatomy to the rat, it is easy and simple to handle, avoided the refastening to the rat, efficiency is higher.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.
Claims (10)
1. Rat crush injury mould, its characterized in that includes:
the upper surface of the base is provided with an inserting groove;
the fixing component is inserted and positioned on the base and used for fixing a rat;
the bottom of the support frame is detachably connected to the support frame, and the top of the support frame is provided with a slide rail; the top of the sliding rail is provided with a clamping groove in a penetrating way;
the extrusion mechanisms are sleeved and arranged on the sliding rails in a sliding mode, extrusion pieces are arranged at the bottoms of the extrusion mechanisms and are used for extruding the legs of the rats; and
the rotating pieces correspond to the extrusion mechanisms one by one, penetrate through the top of the extrusion mechanisms and are in threaded connection with the top of the extrusion mechanisms, and the rotating pieces are clamped and arranged in the clamping grooves in a sliding mode;
the extrusion mechanism drives the rotating piece to slide along the clamping groove; the extrusion mechanism drives the extrusion piece to move downwards by means of the thread force of the rotating piece, and then the leg of the rat is extruded.
2. The rat crush injury die of claim 1, wherein a stopper is fixed to an end of the rotating member adjacent to the sliding rail, and the rotating member drives the stopper to rotate and slidably disposed in the engaging groove.
3. A rat crush injury die as claimed in claim 2 wherein the width of the bottom of the snap groove is greater than the width of the top; the slide rail is the polygon prism structure, the bottom surface in joint groove is the butt face, the butt face with the upper surface parallel arrangement of base.
4. A rat crush injury mold according to claim 1, wherein the squeezing mechanism comprises:
the supporting frame is sleeved on the sliding rail, and the side surface of the inner edge of the supporting frame is in sliding fit with the sliding rail; the top surface and the bottom surface of the inner edge of the supporting frame are both arranged at a certain distance from the sliding rail; the top of the supporting frame is in threaded connection with the rotating piece; and
the extruded article is connected the bottom of carriage, the extruded article is kept away from the reducing groove has been seted up to one side of slide rail, the extruded article with the help of the reducing groove is fixed and is extruded the shank of rat.
5. A rat crush injury mold according to claim 4, wherein the extrusion is connected to a bottom bulb of the support frame.
6. The rat crush injury mold according to claim 1, wherein the base has a fixing groove, a fixing portion is fixed to one side wall of the fixing groove, the fixing portion is spaced apart from the other side wall of the fixing groove by a predetermined distance, and the fixing portion is used for limiting the supporting frame.
7. The rat crush injury mold of claim 1, wherein the insertion groove is disposed along an outer edge of the base; the inserting groove is used for inserting and positioning the outer edges of the two sides of the fixing component.
8. A rat crush injury mold according to claim 1, wherein the fixing assembly comprises:
the fixing frame is of a hollow structure and is inserted into the insertion groove; a plurality of fixing rings are fixed on the inner wall of the fixing frame; the outer edges of the two sides of the fixing frame are respectively used for being plugged and limited with the plugging grooves; and is abutted against the bottom of the inserting groove; and
the fixing pieces correspond to the fixing rings one by one; one end is connected on the fixed ring, and the other end is used for being connected with the leg of the rat.
9. The rat crush injury mold according to claim 1, wherein an avoiding groove is formed in an inner side surface of the extrusion piece, a pressure sensor is fixed in the avoiding groove, and the pressure sensor is used for measuring the extrusion force of the extrusion piece on the leg of the rat; a temperature adjusting device is fixed at the bottom of the base; and a temperature display is arranged on the upper surface of the base.
10. A crush injury experimental method is characterized by comprising the following steps:
fixing a rat on a fixing component, and inserting and limiting one side edge of the fixing component on a base;
adjusting the position of the extrusion mechanism relative to the support frame according to the overall dimension of the rat, and detachably connecting the support frame to the base;
rotating a rotating part in threaded connection with the squeezing mechanism to enable the squeezing mechanism to squeeze the leg of the rat;
after a preset requirement is met, disassembling the support frame and the extrusion mechanism;
and taking out the fixed component, overturning the fixed component, inserting and limiting the other side edge of the fixed component on the base, and dissecting the rat.
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| CN202010194195.3A CN111329612A (en) | 2020-03-18 | 2020-03-18 | Rat crush injury mold and crush injury experimental method |
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