CN111317144A - Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine and preparation method thereof - Google Patents
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine and preparation method thereof Download PDFInfo
- Publication number
- CN111317144A CN111317144A CN202010238340.3A CN202010238340A CN111317144A CN 111317144 A CN111317144 A CN 111317144A CN 202010238340 A CN202010238340 A CN 202010238340A CN 111317144 A CN111317144 A CN 111317144A
- Authority
- CN
- China
- Prior art keywords
- weight
- parts
- oil
- water
- fish collagen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 105
- 102000008186 Collagen Human genes 0.000 title claims abstract description 96
- 108010035532 Collagen Proteins 0.000 title claims abstract description 96
- 229920001436 collagen Polymers 0.000 title claims abstract description 96
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 76
- 239000002131 composite material Substances 0.000 title claims abstract description 67
- 230000035764 nutrition Effects 0.000 title claims abstract description 58
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 210000000813 small intestine Anatomy 0.000 title abstract description 36
- 150000003384 small molecules Chemical class 0.000 title abstract description 29
- 235000015097 nutrients Nutrition 0.000 claims abstract description 87
- 241000251468 Actinopterygii Species 0.000 claims abstract description 81
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 57
- 239000000463 material Substances 0.000 claims abstract description 51
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 43
- 239000003921 oil Substances 0.000 claims abstract description 37
- 239000000843 powder Substances 0.000 claims abstract description 26
- 239000008157 edible vegetable oil Substances 0.000 claims abstract description 21
- 235000010489 acacia gum Nutrition 0.000 claims abstract description 14
- 239000001785 acacia senegal l. willd gum Substances 0.000 claims abstract description 11
- 239000000230 xanthan gum Substances 0.000 claims abstract description 11
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 11
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 11
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 11
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 10
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 10
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 10
- 238000000265 homogenisation Methods 0.000 claims description 53
- 238000002156 mixing Methods 0.000 claims description 34
- 235000019198 oils Nutrition 0.000 claims description 31
- 238000000034 method Methods 0.000 claims description 20
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 18
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 15
- 238000010438 heat treatment Methods 0.000 claims description 10
- 229930003427 Vitamin E Natural products 0.000 claims description 9
- 235000010418 carrageenan Nutrition 0.000 claims description 9
- 239000000679 carrageenan Substances 0.000 claims description 9
- 229920001525 carrageenan Polymers 0.000 claims description 9
- 229940113118 carrageenan Drugs 0.000 claims description 9
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 9
- 150000003904 phospholipids Chemical class 0.000 claims description 9
- 235000019165 vitamin E Nutrition 0.000 claims description 9
- 229940046009 vitamin E Drugs 0.000 claims description 9
- 239000011709 vitamin E Substances 0.000 claims description 9
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 9
- 229930006000 Sucrose Natural products 0.000 claims description 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 8
- 239000000194 fatty acid Substances 0.000 claims description 8
- 229930195729 fatty acid Natural products 0.000 claims description 8
- 239000008518 lycium barbarum polysaccharide Substances 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 8
- 239000005720 sucrose Substances 0.000 claims description 8
- -1 sucrose fatty acid ester Chemical class 0.000 claims description 8
- GIPOFCXYHMWROH-UHFFFAOYSA-L 2-aminoacetate;iron(2+) Chemical compound [Fe+2].NCC([O-])=O.NCC([O-])=O GIPOFCXYHMWROH-UHFFFAOYSA-L 0.000 claims description 7
- 235000010469 Glycine max Nutrition 0.000 claims description 7
- 235000019483 Peanut oil Nutrition 0.000 claims description 7
- 229940075529 glyceryl stearate Drugs 0.000 claims description 7
- 239000000312 peanut oil Substances 0.000 claims description 7
- 239000003549 soybean oil Substances 0.000 claims description 7
- 235000012424 soybean oil Nutrition 0.000 claims description 7
- 239000002285 corn oil Substances 0.000 claims description 6
- 235000005687 corn oil Nutrition 0.000 claims description 6
- 229940080313 sodium starch Drugs 0.000 claims description 6
- GUOCOOQWZHQBJI-UHFFFAOYSA-N 4-oct-7-enoxy-4-oxobutanoic acid Chemical compound OC(=O)CCC(=O)OCCCCCCC=C GUOCOOQWZHQBJI-UHFFFAOYSA-N 0.000 claims description 5
- 235000003687 soy isoflavones Nutrition 0.000 claims description 4
- 244000215068 Acacia senegal Species 0.000 claims description 3
- 229920000084 Gum arabic Polymers 0.000 claims description 3
- 239000000205 acacia gum Substances 0.000 claims description 3
- 239000010699 lard oil Substances 0.000 claims description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- 210000004051 gastric juice Anatomy 0.000 abstract description 24
- 230000029087 digestion Effects 0.000 abstract description 16
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 22
- 230000000694 effects Effects 0.000 description 21
- 239000000047 product Substances 0.000 description 16
- 239000000126 substance Substances 0.000 description 13
- 229910052742 iron Inorganic materials 0.000 description 11
- 235000013305 food Nutrition 0.000 description 10
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- 239000000839 emulsion Substances 0.000 description 9
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 8
- 229930003944 flavone Natural products 0.000 description 8
- 150000002212 flavone derivatives Chemical class 0.000 description 8
- 235000011949 flavones Nutrition 0.000 description 8
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 8
- 230000014759 maintenance of location Effects 0.000 description 7
- 239000006228 supernatant Substances 0.000 description 7
- IZHVBANLECCAGF-UHFFFAOYSA-N 2-hydroxy-3-(octadecanoyloxy)propyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CCCCCCCCCCCCCCCCC IZHVBANLECCAGF-UHFFFAOYSA-N 0.000 description 6
- 244000068988 Glycine max Species 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 238000004090 dissolution Methods 0.000 description 6
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 6
- 229910052757 nitrogen Inorganic materials 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 5
- 235000008696 isoflavones Nutrition 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 229940074045 glyceryl distearate Drugs 0.000 description 3
- 229940075507 glyceryl monostearate Drugs 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000000717 retained effect Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 102000057297 Pepsin A Human genes 0.000 description 2
- 108090000284 Pepsin A Proteins 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000010775 animal oil Substances 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 2
- 229940111202 pepsin Drugs 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 description 1
- DCXXMTOCNZCJGO-UHFFFAOYSA-N Glycerol trioctadecanoate Natural products CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 1
- 240000007472 Leucaena leucocephala Species 0.000 description 1
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 1
- 244000241838 Lycium barbarum Species 0.000 description 1
- 235000015459 Lycium barbarum Nutrition 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 241000282894 Sus scrofa domesticus Species 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000017471 coenzyme Q10 Nutrition 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical group COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 229940110767 coenzyme Q10 Drugs 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 210000003701 histiocyte Anatomy 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- KCYQMQGPYWZZNJ-BQYQJAHWSA-N hydron;2-[(e)-oct-1-enyl]butanedioate Chemical compound CCCCCC\C=C\C(C(O)=O)CC(O)=O KCYQMQGPYWZZNJ-BQYQJAHWSA-N 0.000 description 1
- 239000001341 hydroxy propyl starch Substances 0.000 description 1
- 235000013828 hydroxypropyl starch Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000005847 immunogenicity Effects 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 238000009862 microstructural analysis Methods 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- UQDVHJGNIFVBLG-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O UQDVHJGNIFVBLG-UHFFFAOYSA-N 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 235000013826 starch sodium octenyl succinate Nutrition 0.000 description 1
- 239000001334 starch sodium octenyl succinate Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/25—Exudates, e.g. gum arabic, gum acacia, gum karaya or tragacanth
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/269—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
- A23L29/27—Xanthan not combined with other microbial gums
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to the technical field of collagen products, in particular to a fish collagen small molecular peptide composite nutrition bag capable of directly reaching small intestine and a preparation method thereof. The nutrition comprises fish collagen peptide powder, water-soluble nutrients, edible oil, an oil-based emulsifier, oil-soluble nutrients, a composite wall material and a water-based emulsifier; the composite wall material contains 16-36 parts by weight of Arabic gum and 1-3 parts by weight of xanthan gum relative to 100 parts by weight of maltodextrin. The fish collagen small molecule peptide composite nutrition packet capable of directly reaching the small intestine provided by the invention can effectively resist the digestion of gastric juice, so that the nutrient components can directly reach the small intestine and can be more effectively absorbed.
Description
Technical Field
The invention relates to the technical field of collagen products, in particular to a fish collagen small molecular peptide composite nutrition bag capable of directly reaching small intestine and a preparation method thereof.
Background
Collagen is a biological macromolecule, is a main component in animal connective tissues, is also a functional protein with the largest content and the widest distribution in mammals, and accounts for 25-30 wt% of the total protein. The collagen has the advantages of very low immunogenicity, good biocompatibility with human cells and tissues, biodegradability, coagulability and the like, and is widely applied to the industries of medicine, food, beauty treatment, health care and the like. The fish skin and the fish scales contain rich collagen, which accounts for more than 30 percent of the weight of the fresh fish skin and the fish scales, and is a good collagen preparation material.
The peptide is a compound formed by connecting two or more amino acids through peptide bonds, the connection mode of the peptide is the same as that of protein, and the relative molecular mass is less than 10000 Da. The peptide has the characteristics of high absorption speed, high efficiency, less energy consumption of a human body and the like due to low molecular weight, and plays an important physiological role in the human body. Scientific research shows that the peptide has important physiological activity including enhancing immunity, promoting wound healing, repairing cells, regulating blood pressure and the like, the fish collagen peptide has unique functions in the aspects of maintaining beauty and keeping young, repairing histiocyte, resisting aging and the like, and the biological activity of the small molecular peptide with the molecular weight lower than 1000Da is higher. To increase the biological activity of fish collagen, fish collagen is usually processed into fish collagen polypeptides or small peptides.
At present, the fish collagen peptide products in the market are mostly consumed in the form of peptide powder or peptide beverage, and the polypeptide or small peptide is digested by gastric juice and is hydrolyzed into amino acid after entering a human body, so that the function of the peptide cannot be fully exerted.
Disclosure of Invention
The invention aims to overcome the defect that a fish collagen product is easily digested by gastric juice in the prior art, and provides a fish collagen small molecular peptide compound nutrition bag which can resist gastric juice digestion and directly reach the small intestine and a preparation method thereof. The fish collagen small molecule peptide composite nutrition packet capable of directly reaching the small intestine provided by the invention can effectively resist the digestion of gastric juice, so that the nutrient components can directly reach the small intestine and can be more effectively absorbed.
In order to achieve the above objects, in a first aspect, the present invention provides a fish collagen peptide complex nutritional package, which comprises fish collagen peptide powder, water-soluble nutrients, edible oil, an oil-based emulsifier, oil-soluble nutrients, a complex wall material and a water-based emulsifier; the composite wall material contains 16-36 parts by weight of Arabic gum and 1-3 parts by weight of xanthan gum relative to 100 parts by weight of maltodextrin.
In a second aspect, the invention provides a preparation method of a fish collagen peptide composite nutrition packet, which comprises the following steps:
(1) performing first mixing on fish collagen peptide powder, water-soluble nutrients and water to obtain a water-based nutritional core;
(2) secondly, mixing the edible oil, the oil-soluble nutrient and the oil-based emulsifier, then adding the aqueous nutrient core into the obtained oily nutrient, and carrying out first homogenization treatment on the obtained mixture;
(3) and (3) carrying out third mixing on the composite wall material, the water-based emulsifier and water to obtain a water-based wall material, then adding the material subjected to the homogenization treatment in the step (2) into the obtained water-based wall material, and carrying out second homogenization treatment on the obtained mixture to obtain the fish collagen peptide composite nutrition bag.
In a third aspect, the invention provides a fish collagen peptide complex nutritional package prepared by the method described above.
Through the technical scheme of the invention, the following beneficial effects can be achieved:
1. the invention adopts the composite wall materials (maltodextrin, xanthan gum and Arabic gum) with specific compositions, and the components are cooperated and matched, thereby effectively resisting the digestion of gastric juice. And preferably, in the composite wall material, the capability of resisting gastric juice digestion is further improved under the condition that the content of the Arabic gum is not less than 14 weight percent.
2. The invention preferably adds antioxidant and/or anti-aging components, including phospholipid, soybean isoflavone, vitamin E, lycium barbarum polysaccharide or ferrous glycinate, etc. into the formula, and can effectively assist the fish collagen small molecular peptide to exert bioactivity after entering a human body.
3. The preparation method adopts a twice embedding technology, and firstly adopts edible oil dissolved with oil-soluble nutrients to embed the water-soluble nutrients to form water-in-oil (W/O) type emulsion, thereby realizing the protection of the water-soluble nutrients. Then, the composite wall materials (maltodextrin, xanthan gum and Arabic gum) are adopted to embed the water-in-oil (W/O) type emulsion again to form a water-in-oil-in-water (W/O/W) type emulsion, so that the protection of oil-soluble nutrients and the further protection of oil-embedded water-soluble nutrients are realized, and the embedding rate of nutrient substances is effectively improved. After the product is eaten, the release amount of each nutrient in gastric juice is small under protection, and the nutrient is mainly released in small intestines, so that the bioactive function can be more effectively exerted.
4. Preferably, the encapsulation efficiency of the fish collagen peptide can be further improved by specific homogenization conditions, and more preferably, the encapsulation efficiency can be further improved by setting the first homogenization to 2 stages and setting the pressure of the second homogenization to be lower than the pressure of the second homogenization in the first homogenization.
Additional features and advantages of the invention will be set forth in the detailed description which follows.
Detailed Description
The endpoints of the ranges and any values disclosed herein are not limited to the precise range or value, and such ranges or values should be understood to encompass values close to those ranges or values. For ranges of values, between the endpoints of each of the ranges and the individual points, and between the individual points may be combined with each other to give one or more new ranges of values, and these ranges of values should be considered as specifically disclosed herein.
In a first aspect, the invention provides a fish collagen peptide composite nutrition package, which comprises fish collagen peptide powder, water-soluble nutrients, edible oil, an oil-based emulsifier, oil-soluble nutrients, a composite wall material and a water-based emulsifier;
the composite wall material contains 16-36 parts by weight of Arabic gum and 1-3 parts by weight of xanthan gum relative to 100 parts by weight of maltodextrin.
Preferably, in order to further improve the ability of the composite nutritional pack to resist digestion by gastric juice, the gum arabic is contained in an amount of 20 to 31.5 parts by weight (for example, 20 parts by weight, 21 parts by weight, 22 parts by weight, 23 parts by weight, 24 parts by weight, 25 parts by weight, 26 parts by weight, 27 parts by weight, 28 parts by weight, 29 parts by weight, 30 parts by weight, 31 parts by weight, 31.5 parts by weight) and the xanthan gum is contained in an amount of 1.4 to 2.2 parts by weight (for example, 1.4 parts by weight, 1.5 parts by weight, 1.6 parts by weight, 1.7 parts by weight, 1.8 parts by weight, 1.9 parts by weight, 2 parts by weight, 2.1 parts by weight, 2.2 parts by weight) with respect to 100 parts by weight of maltodextrin.
According to the present invention, in order to further improve the effect of the present invention, the nutritional supplement has the following structure:
the nutrition bag sequentially comprises a water-based nutrition core, an oily nutrition layer and a water-based wall material layer from inside to outside;
wherein the aqueous nutrient core comprises fish collagen peptide powder and water-soluble nutrients;
the oily nutrient layer contains edible oil, an oil-based emulsifier and oil-soluble nutrients;
the water-based wall material layer contains a composite wall material and a water-based emulsifier.
Although the composite wall material can provide the fish collagen peptide composite nutrition packet with the capability of resisting gastric juice digestion and directly reaching the small intestine according to the proportion, the inventor of the invention finds in the research process that when the content of the Arabic gum in the composite wall material is not less than 14 weight percent, the capability of the composite nutrition packet for resisting gastric juice digestion can be further enhanced, so that substances in an aqueous nutrition core and an oily nutrition layer can be better protected, and the embedding effect on nutrient substances (the core and the oil layer) can be improved.
Although the composite wall material can provide the fish collagen peptide composite nutrition packet with the capability of resisting gastric juice digestion and directly reaching the small intestine according to the proportion, the inventor of the invention finds in the research process that when the content of the Arabic gum in the composite wall material is not less than 14 weight percent, the capability of the composite nutrition packet for resisting gastric juice digestion can be further enhanced, so that substances in an aqueous nutrition core and an oily nutrition layer can be better protected, and the embedding effect on nutrient substances (the core and the oil layer) can be improved.
According to the present invention, the fish collagen peptide powder can be various commercially available fish collagen peptide powders, for example, peptides with a relative molecular mass of less than 10000Da, but in order to further improve the absorption and utilization of the fish collagen peptide powder by the body, it is preferable that the peptides contained in the fish collagen peptide powder are small molecular peptides with a molecular weight of preferably not more than 1000 Da. Further preferably, the fish collagen peptide powder contains fish collagen peptides in an amount of not less than 85% by weight.
According to the invention, the water-soluble nutrient can be various conventional water-soluble nutrients used for increasing the nutritional value of the product, but the inventor of the invention finds that when the water-soluble nutrient contains ferrous glycinate and lycium barbarum polysaccharide, on one hand, the corresponding nutrient can be provided, on the other hand, the dissolution of substances in the water-soluble nutrient core in gastric juice can be further reduced, the dissolution is cooperated with an oil layer to improve the embedding effect, and on the other hand, the fish collagen small molecular peptide can be effectively assisted to exert the bioactivity after entering the organism. Thus, preferably, the water-soluble nutrient comprises ferrous glycinate and lycium barbarum polysaccharide. Wherein, the weight ratio of the ferrous glycinate to the lycium barbarum polysaccharide is preferably 1:1-2, for example, 1:1, 1:1.2, 1:1.3, 1:1.4, 1:1.5, 1:1.6, 1:1.7, 1:1.8, 1:1.9 and 1:2, and more preferably, the weight ratio of the ferrous glycinate to the lycium barbarum polysaccharide is 1: 1.3-1.7.
According to the present invention, in the oily nutrient layer, the edible oil may be various conventional edible oils as long as the oil-soluble nutrients can be dissolved. However, the inventors of the present invention have found that when the edible oil comprises animal oil and vegetable oil, particularly a mixed oil of lard, soybean oil, peanut oil and corn oil, on the one hand, the oil-soluble nutrients can be effectively dissolved, and on the other hand, the formed oil layer can better prevent the dissolution of the core nutrients in gastric juice, thereby improving the embedding effect on the aqueous nutrient core, and on the other hand, the embedding of the formed oil layer by the aqueous wall material layer is also facilitated. Therefore, preferably, the edible oil contains animal oil and vegetable oil, and more preferably contains lard, soybean oil, peanut oil and corn oil.
Among them, in order to further improve the above effect, it is preferable that the content of the soybean oil is 7 to 140 parts by weight (for example, 7 parts by weight, 14 parts by weight, 21 parts by weight, 28 parts by weight, 35 parts by weight, 42 parts by weight, 49 parts by weight, 56 parts by weight, 63 parts by weight, 70 parts by weight, 77 parts by weight, 84 parts by weight, 91 parts by weight, 98 parts by weight, 105 parts by weight, 112 parts by weight, 119 parts by weight, 126 parts by weight, 133 parts by weight, 140 parts by weight) and the content of the peanut oil is 7 to 140 parts by weight (for example, 7 parts by weight, 14 parts by weight, 16.5 parts by weight, 17.5 parts by weight, 18.5 parts by weight, 19.5 parts by weight, 20.5 parts by weight, 21.5 parts by weight, 22.5 parts by weight, 23.5 parts by weight, 24.5 parts by weight, 25.5 parts by weight, 26.5 parts by weight, 27.5 parts by weight, 28.5 parts by weight, 35 parts by weight, 42 parts by weight, 100 parts by, 49 parts by weight, 56 parts by weight, 63 parts by weight, 70 parts by weight, 77 parts by weight, 84 parts by weight, 91 parts by weight, 98 parts by weight, 105 parts by weight, 112 parts by weight, 119 parts by weight, 126 parts by weight, 133 parts by weight, 140 parts by weight), and a content of corn oil of 7 to 140 parts by weight (for example, 7 parts by weight, 13 parts by weight, 19 parts by weight, 25 parts by weight, 31 parts by weight, 37 parts by weight, 43 parts by weight, 50 parts by weight, 56 parts by weight, 62 parts by weight, 68 parts by weight, 74 parts by weight, 80 parts by weight, 85 parts by weight, 91 parts by weight, 98 parts by weight, 105 parts by weight, 112 parts by weight, 119 parts by weight, 126 parts by weight, 133 parts by weight, 140 parts by weight); more preferably, the soybean oil content is 14 to 119 parts by weight, the peanut oil content is 16.5 to 28.5 parts by weight, and the corn oil content is 13 to 85 parts by weight, relative to 100 parts by weight of lard oil.
According to the present invention, the oil-based emulsifier may be any conventional oil-soluble emulsifier as long as the mixing effect of the components of the oil phase can be improved. In order to further improve the entrapment effect of the nutrient substance and to reduce the dissolution of the nutrient substance in gastric juice, it is preferable that the oil-based emulsifier contains glyceryl stearate and sucrose fatty acid ester. Wherein, the glyceryl stearate is preferably glyceryl monostearate and glyceryl distearate, which is a mixture and is a product defined by the standard of GB 1986-2007 food additive glyceryl monostearate and glyceryl distearate (the standard is applicable to hydrogenated palm oil or a product which is generated by the reaction of stearic acid and glycerol and contains glyceryl monostearate and glyceryl distearate in small amount and is used as an emulsifier in the food industry).
The content of the glyceryl stearate and the sucrose fatty acid ester may be varied within a wide range, and the weight ratio of the glyceryl stearate to the sucrose fatty acid ester is preferably 1:1 to 2, for example, 1:1, 1:1.2, 1:1.3, 1:1.4, 1:1.5, 1:1.6, 1:1.7, 1:1.8, 1:1.9, 1:2, and more preferably 1.4 to 1.8.
According to the invention, the oil-soluble nutrient can be various conventional oil-soluble nutrients which are used for increasing the nutritional value of the product, but the inventor of the invention finds that when the oil-soluble nutrient contains phospholipid, soybean isoflavone and vitamin E, on one hand, the corresponding nutrient can be provided, on the other hand, the embedding effect on core nutrient substances can be further improved, the embedding effect on the oily nutrient substances is improved by cooperating with the aqueous wall material layer, and on the other hand, the fish collagen small molecular peptide can be effectively assisted to exert bioactivity after entering the organism. Thus, the oil-soluble nutrient contains phospholipids, soy isoflavones, and vitamin E.
The content of each component in the oil-soluble nutrient may be selected from a wide range, and preferably, in order to further improve the above effect, the content of soybean isoflavone is 1 to 3 parts by weight (for example, 1 part by weight, 1.2 parts by weight, 1.4 parts by weight, 1.5 parts by weight, 1.6 parts by weight, 1.7 parts by weight, 1.8 parts by weight, 2 parts by weight, 2.2 parts by weight, 2.4 parts by weight, 2.6 parts by weight, 2.8 parts by weight, 3 parts by weight) and the content of vitamin E is 0.1 to 0.6 parts by weight (for example, 0.1 part by weight, 0.15 part by weight, 0.16 part by weight, 0.18 part by weight, 0.2 part by weight, 0.22 part by weight, 0.24 part by weight, 0.26 part by weight, 0.28 part by weight, 0.3 part by weight, 0.35 part by weight, 0.4 part by weight, 0.45 part by weight, 0.55 part by weight) with respect to 100 parts by weight of the phospholipid. More preferably, the content of soy isoflavone is 1.4-1.8 parts by weight and the content of vitamin E is 0.16-0.3 parts by weight with respect to 100 parts by weight of phospholipid.
According to the invention, in the aqueous wall material layer, the water-based emulsifier can be any conventional water-soluble emulsifier as long as the mixing effect of the components in the composite wall material can be improved. In order to further improve the embedding effect of the nutrient substances and reduce the dissolution of the nutrient substances in gastric juice, it is preferable that the water-based emulsifier contains octenyl succinic acid sodium starch and carrageenan.
The content of sodium starch octenylsuccinate and carrageenan can be changed in a wide range, preferably, the weight ratio of sodium starch octenylsuccinate to carrageenan is 7 (3.5-7), for example, 7:3.5, 7:4, 7:4.5, 7:5, 7:5.5, 7:6, 7:6.5, 7:7, and more preferably, the weight ratio of glyceryl stearate to sucrose fatty acid ester is 7 (4-6).
According to the present invention, the amount of each component in the fish collagen peptide complex nutrition pack may be varied within a wide range, but in order to further improve the embedding effect of the nutrients and reduce the dissolution rate in gastric juice, it is preferable that the content of the water-soluble nutrients is 12.5 to 40 parts by weight (for example, may be 12.5 parts by weight, 14.5 parts by weight, 17.5 parts by weight, 18.5 parts by weight, 19.5 parts by weight, 20 parts by weight, 21 parts by weight, 22 parts by weight, 23 parts by weight, 24 parts by weight, 25 parts by weight, 28 parts by weight, 33 parts by weight, 37 parts by weight, 40 parts by weight) and the content of the edible oil is 290 parts by weight (for example, may be 290 parts by weight, 320 parts by weight, 350 parts by weight, 370 parts by weight, 380 parts by weight, 390 parts by weight, 400 parts by weight, 410 parts by weight, 420 parts by weight, 430 parts by weight) with respect to 100 parts by weight of the fish collagen peptide powder, 440 parts, 450 parts, 460 parts, 470 parts, 500 parts, 525 parts, 550 parts, 575 parts, 600 parts by weight), 6 to 24 parts (for example, 6 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 16 parts, 19 parts, 22 parts, 24 parts) by weight of an oil-based emulsifier, 20 to 70 parts (for example, 20 parts, 24 parts, 28 parts, 28.5 parts, 30.5 parts, 32.5 parts, 34.5 parts, 36.5 parts, 38.5 parts, 40.5 parts, 42.5 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts) by weight of an oil-soluble nutrient, 415 parts (for example, 415 parts by weight) by weight of a composite wall material, and 800 parts (for example, 415 parts by weight) by weight of a composite wall material, 445 parts by weight, 500 parts by weight, 510 parts by weight, 520 parts by weight, 530 parts by weight, 540 parts by weight, 550 parts by weight, 560 parts by weight, 570 parts by weight, 580 parts by weight, 590 parts by weight, 600 parts by weight, 610 parts by weight, 615 parts by weight, 650 parts by weight, 700 parts by weight, 750 parts by weight, 800 parts by weight), and the content of the water-based emulsifier is 14.5 to 47 parts by weight (for example, 14.5 parts by weight, 17.5 parts by weight, 18.5 parts by weight, 20 parts by weight, 21 parts by weight, 22 parts by weight, 23 parts by weight, 24 parts by weight, 25 parts by weight, 29 parts by weight, 33 parts by weight, 37 parts by weight, 41 parts by weight, 44 parts by weight, 47 parts by weight may be mentioned above).
More preferably, relative to 100 weight parts of fish collagen peptide powder, the content of the water-soluble nutrient is 17.5 to 25 weight parts, the content of the edible oil is 370-470 weight parts, the content of the oil-based emulsifier is 9 to 13 weight parts, the content of the oil-soluble nutrient is 28 to 42.5 weight parts, the content of the composite wall material is 500-615 weight parts, and the content of the water-based emulsifier is 17.5 to 25 weight parts.
In a second aspect, the invention provides a preparation method of a fish collagen peptide composite nutrition packet, which comprises the following steps:
(1) performing first mixing on fish collagen peptide powder, water-soluble nutrients and water to obtain a water-based nutritional core;
(2) secondly, mixing the edible oil, the oil-soluble nutrient and the oil-based emulsifier, then adding the water-based nutrient core into the obtained oily nutrient, and carrying out first homogenization treatment on the obtained mixture to prepare a water-in-oil type emulsion;
(3) and (3) carrying out third mixing on the composite wall material, the water-based emulsifier and water to obtain a water-based wall material, then adding the material subjected to the homogenization treatment in the step (2) into the obtained water-based wall material, and carrying out second homogenization treatment on the obtained mixture to prepare a water-in-oil-in-water emulsion so as to obtain the fish collagen peptide composite nutrition bag.
According to the present invention, in the step (1), the amount of water to be used may be selected from a wide range as long as the fish collagen peptide powder and the water-soluble nutrient can be dissolved. Preferably, the amount of water is 205-400 parts by weight, more preferably 252-275 parts by weight, relative to 100 parts by weight of the fish collagen peptide powder.
In the step (1), the method of the first mixing is not particularly limited as long as the components can be mixed, for example, stirring.
According to the present invention, in the step (2), the method of the second mixing is not particularly limited as long as the components in the oil phase can be mixed, for example, stirring.
According to the present invention, in order to enhance the mixing effect of the components, the second mixing is preferably performed under heating, the heating temperature is preferably 60 to 70 ℃, and specifically, the second mixing may include: heating edible oil to 60-70 deg.C, and adding oil soluble nutrient and oil-based emulsifier.
According to the present invention, the conditions for the first homogenization can be selected from a wide range, and it is preferable that the pressure for the first homogenization is 20 to 60MPa, for example, 20MPa, 25MPa, 30MPa, 35MPa, 40MPa, 45MPa, 50MPa, 55MPa, or 60MPa, in order to increase the embedding rate in the water-in-oil emulsion. The number of homogenisations may be 1-5.
In order to further improve the embedding effect of the oil with respect to the water phase, the first homogenization includes a first-stage homogenization and a second-stage homogenization, preferably, the pressure of the second-stage homogenization is greater than the pressure of the first-stage homogenization, more preferably, the pressure of the first-stage homogenization is 20-30MPa (for example, 20MPa, 22MPa, 24MPa, 26MPa, 28MPa, 30MPa, preferably 21-25MPa), the number of homogenization times may be 1-3, the pressure of the second-stage homogenization is 40-60MPa (for example, 40MPa, 45MPa, 50MPa, 55MPa, 60MPa, preferably 50-58MPa), and the number of homogenization times may be 1-3.
According to the present invention, in step (3), the amount of water may be selected from a wide range, as long as the composite wall material and the water-based emulsifier can be dissolved. Preferably, the amount of water is 458-1130 parts by weight, more preferably 740-870 parts by weight, relative to 100 parts by weight of the composite wall material.
According to the present invention, the method of the third mixing is not particularly limited as long as the components in the oil phase can be mixed, for example, by stirring.
According to the present invention, in order to enhance the mixing effect of the components, the third mixing is preferably performed under heating, the heating temperature is preferably 70-80 ℃, and specifically, the third mixing may include: mixing the composite wall material, the water-based emulsifier and water, heating to 70-80 ℃, and uniformly mixing the components.
According to the present invention, the pressure of the second homogenization can be changed in a wide range, and in the case where the first homogenization preferably includes the first-stage homogenization and the second-stage homogenization as described above, the pressure of the second homogenization is smaller than the pressure of the second-stage homogenization in the first homogenization, and further preferably larger than the pressure of the first-stage homogenization. Preferably, the pressure of the second homogenization is 20 to 30MPa, for example, 20MPa, 22MPa, 24MPa, 26MPa, 28MPa, 30MPa, preferably 21 to 28 MPa. The number of homogenisations may be 1-5.
According to the invention, the method also comprises drying the fish collagen peptide composite nutrition bag. Wherein the drying may be spray drying.
In a third aspect, the invention provides a fish collagen peptide complex nutritional package prepared by the method described above.
The present invention will be described in detail below by way of examples. In the following examples and comparative examples:
the fish collagen small molecule peptide powder is purchased from Jiangxi Fumantai biotechnology limited company, the product number is FYP20190418, the relative molecular mass of the contained fish collagen small molecule peptide is lower than 1000Da, and the content (calculated by dry basis) is not lower than 85 weight percent.
Examples 1 to 5
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
(i) Preparing a composite wall material: mixing maltodextrin, arabic gum and xanthan gum.
(ii) Preparing edible oil: mixing adeps Sus Domestica, Soybean oil, oleum Arachidis Hypogaeae and oleum Maydis.
(iii) Preparing oil-soluble compound nutrients: mixing phospholipid, soybean isoflavone and vitamin E.
(iv) Preparing water-soluble compound nutrients: mixing ferrous glycinate and lycium barbarum polysaccharide completely.
(v) Preparing a water-based emulsifier: taking sodium starch octenylsuccinate and carrageenan, and fully mixing.
(vi) Preparing an oil-based emulsifier: mixing glycerin monostearate, glycerin distearate and sucrose fatty acid ester.
The preparation method of the fish collagen small molecular peptide composite nutrition bag capable of directly reaching the small intestine comprises the following steps:
(1) taking fish collagen small molecular peptide powder and water-soluble compound nutrients, adding water, and uniformly mixing to obtain a water-based nutrition core;
(2) heating edible oil, adding an oil-based emulsifier, mixing uniformly, adding the water-based nutrition core prepared in the step (1), performing first homogenization (including first-stage homogenization and second-stage homogenization) by using a homogenizer to prepare water-in-oil (W/O) type emulsion, drying part of the emulsion, and performing microstructure analysis to verify that the embedding structure with the core and the first wrapping layer is obtained.
(3) Adding water and a water-based emulsifier into the composite wall material, heating, uniformly mixing, adding the water-in-oil (W/O) type emulsion prepared in the step (2), performing second homogenization by adopting a homogenizer to prepare a water-in-oil-in-water (W/O/W) type emulsion, and maintaining the temperature of the materials;
(4) and (3) drying the water/oil/water (W/O/W) emulsion prepared in the step (3) by adopting a spray drying method, conveying the fed materials by adopting a homogenizer, and controlling the homogenizer to be 20MPa to obtain the fish collagen small molecular peptide compound nutrition packet capable of directly reaching the small intestine. A portion of the nutrition packet was taken for microstructural analysis, confirming that an embedded structure with a second coating was obtained.
Wherein the amounts of the components and the conditions of the steps are shown in Table 1.
TABLE 1
Example 6
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
Preparation of a fish collagen small molecule peptide complex nutritional package that could reach the small intestine was performed according to the method of example 1, except that the lycium barbarum polysaccharides in the water-soluble nutrients were replaced with the same amount of soybean polysaccharides.
Example 7
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
Preparation of a fish collagen small molecule peptide complex nutritional package that could reach the small intestine was performed as in example 1, except that soybean oil was replaced with an equal amount of sunflower oil and peanut oil was replaced with an equal amount of rapeseed oil.
Example 8
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
Preparation of a fish collagen small-molecule peptide complex nutrition pack which can reach the small intestine was performed according to the method of example 1, except that the stearin in the oil-based emulsifier was replaced with an equal amount of magnesium stearate and the sucrose fatty acid ester was replaced with an equal amount of ammonium phospholipid.
Example 9
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
Preparation of a fish collagen small molecule peptide complex nutritional pack which could reach the small intestine was performed according to the method of example 1, except that phospholipids in the oil-soluble nutrients were replaced with the same amount of coenzyme Q10 and vitamin E was replaced with the same amount of carotene.
Example 10
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
Preparation of a fish collagen small molecule peptide complex nutritional packet that could reach the small intestine was performed as in example 1, except that the starch sodium octenyl succinate in the water-based emulsifier was replaced with an equal amount of hydroxypropyl starch and the carrageenan was replaced with an equal amount of acacia.
Example 11
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
The preparation of the fish collagen small molecule peptide complex nutrition packet which can directly reach the small intestine is carried out according to the method of the embodiment 1, except that the carrageenan in the water-based emulsifier is completely introduced into the complex wall material.
Example 12
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
The preparation of the fish collagen small molecule peptide complex nutrition pack which can reach the small intestine was performed according to the method of example 1, except that the first homogenization was not divided into the first-stage homogenization and the second-stage homogenization, but only 1 stage at a pressure of 50MPa was performed 4 times.
Example 13
Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine for illustrating the invention
The preparation of the fish collagen small molecule peptide complex nutrition pack which can reach the small intestine was performed according to the method of example 1, except that the pressure for the first stage of homogenization was 21MPa, the pressure for the second stage of homogenization was 30MPa, and the pressure for the second stage of homogenization was 50 MPa.
Comparative example 1
Fish collagen small molecule peptide composite nutrition bag for explaining reference
The preparation of the fish collagen small molecule peptide composite nutrition pack was performed according to the method of example 1, except that 12.5 parts by weight of maltodextrin, gum arabic and xanthan gum were used with respect to 100 parts by weight.
Comparative example 2
Fish collagen small molecule peptide composite nutrition bag for explaining reference
Preparation of a fish collagen small molecule peptide complex nutritional packet was performed according to the method of example 1, except that xanthan gum was replaced with carrageenan in an equal amount.
Test example 1
Evaluation experiment of nutrient direct to small intestine
1. Evaluation experiment of water-soluble nutrient direct to small intestine:
determination of dissolved iron content in vitro digestion experiment: artificial gastric juice (pepsin activity 10000U) is prepared according to the 0921 fourth part of the 2015 edition of Chinese pharmacopoeia. Accurately weighing 10g of sample (accurate to 0.01g), adding 100mL of artificial gastric juice, digesting in a shaking table at the temperature of 37 ℃ in the dark for 2h, centrifuging at 4000r/min for 5min by adopting a centrifuge, taking supernatant, measuring the content of iron in the supernatant according to GB5009.90-2016 (national standard food for food safety) for measuring the content of iron in the supernatant, and calculating the mass of dissolved zinc.
And (3) total iron content determination: the total iron content of the product is determined according to GB5009.90-2016 (determination of iron in food safety national standard food).
Keeping the iron content: the total iron content minus the dissolved iron content is the retained iron content.
The retention of water-soluble nutrients in the product was evaluated by calculating the proportion of iron retained after in vitro digestion according to formula (1), and the higher the retention ratio (retention rate), the better the protection effect of the water-soluble nutrients, and the results are shown in table 2.
2. Evaluation experiment of oil-soluble nutrient direct to small intestine:
determination of dissolved flavone content by in vitro digestion experiment: artificial gastric juice (pepsin activity 10000U) is prepared according to the 0921 fourth part of the 2015 edition of Chinese pharmacopoeia. Accurately weighing 10g of sample (accurate to 0.01g), adding 100mL of artificial gastric juice, carrying out table shaking digestion at the temperature of 37 ℃ in the dark for 2h, centrifuging at 4000r/min for 5min by adopting a centrifuge, taking the supernatant, measuring the content of flavone in the supernatant according to GB/T23788-.
And (3) total flavone content determination: the content of the total flavonoids in the product is determined according to GB/T23788-2009 high performance liquid chromatography for determination of soybean isoflavones in health food.
And (3) retaining the flavone content: the content of the total flavone is subtracted by the content of the dissolved flavone to obtain the content of the remaining flavone.
The ratio of the flavone retained after in vitro digestion is calculated according to the formula (2) to evaluate the retention condition of the oil-soluble nutrient of the product, and the higher the retention ratio (retention rate), the better the protection effect of the oil-soluble nutrient, and the result is shown in table 2.
Test example 2
Testing the embedding rate of the fish collagen small molecular peptide
And (3) measuring the content of free small molecule peptide amino-terminal nitrogen: about 10g (to 0.01g) of sample is accurately weighed into a 500ml beaker, and the weight ratio of the sample is 10: 1, adding purified water, stirring gently by using a glass cup, standing for 1min after the powder is uniformly dispersed, centrifuging for 5min at 4000r/min by using a centrifugal machine, taking supernatant, and measuring the content of amino-terminal nitrogen of the small molecular peptide in the supernatant according to a second method of GB 5009.235-2016 (national standard for food safety) on measuring amino-acid nitrogen in food.
And (3) determining the content of nitrogen at the amino terminal of the total small molecular peptide: accurately weighing product powder with the mass (m) of about 10g (accurate to 0.01g) in a 500ml beaker, and mixing the product powder with the weight ratio of 10: 1, adding purified water, homogenizing for 1min at 9000r/min by using a tissue disruption homogenizer, centrifuging for 5min at 4000r/min by using a centrifuge, taking supernate, and measuring the content of nitrogen at the amino terminal of the total small molecular peptide in the product according to a second method of GB 5009.235-2016 (determination of amino acid nitrogen in food safety national standard food).
The embedding rate of the fish collagen small molecule peptide was calculated according to the formula (3), and the results are shown in table 2.
TABLE 2
As can be seen from the table 2, the fish collagen small molecular peptide composite nutrition packet capable of directly reaching the small intestine prepared by the invention can effectively resist the digestion of gastric juice, and the nutrient substances have higher retention rate after being treated by the gastric juice. In addition, the fish collagen small molecular peptide in the fish collagen small molecular peptide composite nutrition bag capable of directly reaching the small intestine prepared by the invention has higher embedding rate.
The preferred embodiments of the present invention have been described above in detail, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, many simple modifications can be made to the technical solution of the invention, including combinations of various technical features in any other suitable way, and these simple modifications and combinations should also be regarded as the disclosure of the invention, and all fall within the scope of the invention.
Claims (10)
1. A fish collagen peptide composite nutrition package is characterized in that the nutrition comprises fish collagen peptide powder, water-soluble nutrients, edible oil, an oil-based emulsifier, oil-soluble nutrients, composite wall materials and a water-based emulsifier;
the composite wall material contains maltodextrin, Arabic gum and xanthan gum, wherein the content of the Arabic gum is 16-36 parts by weight and the content of the xanthan gum is 1-3 parts by weight relative to 100 parts by weight of the maltodextrin; in the composite wall material, the content of the gum arabic is preferably not less than 14% by weight.
2. The composite nutrition pack of claim 1, wherein the nutrition pack comprises, in order from inside to outside, an aqueous nutrition core, an oily nutrition layer and an aqueous wall material layer;
wherein the aqueous nutrient core comprises fish collagen peptide powder and water-soluble nutrients;
the oily nutrient layer contains edible oil, an oil-based emulsifier and oil-soluble nutrients;
the water-based wall material layer contains a composite wall material and a water-based emulsifier.
3. The fish collagen peptide complex nutritional package according to claim 1 or 2, wherein the fish collagen peptide powder contains fish collagen peptides with a molecular weight of not higher than 1000Da and a content of not lower than 85 wt%;
preferably, the water-soluble nutrient contains ferrous glycinate and lycium barbarum polysaccharide; the weight ratio of the ferrous glycine to the lycium barbarum polysaccharide is preferably 1: 1-2.
4. The fish collagen peptide complex nutritional package of any one of claims 1 to 3, wherein the edible oil comprises lard, soy oil, peanut oil, and corn oil;
preferably, the content of soybean oil is 7-140 parts by weight, the content of peanut oil is 7-140 parts by weight, and the content of corn oil is 7-140 parts by weight, relative to 100 parts by weight of lard oil;
preferably, the oil-based emulsifier contains glyceryl stearate and sucrose fatty acid ester; the weight ratio of the glyceryl stearate to the sucrose fatty acid ester is preferably 1: 1-2;
preferably, the oil-soluble nutrient contains phospholipids, soy isoflavones and vitamin E; preferably, the content of soy isoflavone is 1-3 parts by weight and the content of vitamin E is 0.1-0.6 part by weight with respect to 100 parts by weight of phospholipid.
5. The fish collagen peptide complex nutritional package according to any one of claims 1 to 4, wherein the water-based emulsifier comprises sodium starch octenyl succinate and carrageenan;
preferably, the weight ratio of sodium starch octenyl succinate to carrageenan is 7: 3.5-7.
6. The fish collagen peptide composite nutrition package according to any one of claims 1 to 5, wherein, relative to 100 parts by weight of fish collagen peptide powder, the content of the water-soluble nutrient is 12.5 to 40 parts by weight, the content of the edible oil is 290 parts by weight, the content of the oil-based emulsifier is 6 to 24 parts by weight, the content of the oil-soluble nutrient is 20 to 70 parts by weight, the content of the composite wall material is 415 parts by weight, and the content of the water-based emulsifier is 14.5 to 47 parts by weight.
7. A preparation method of a fish collagen peptide composite nutrition bag is characterized by comprising the following steps:
(1) performing first mixing on fish collagen peptide powder, water-soluble nutrients and water to obtain a water-based nutritional core;
(2) secondly, mixing the edible oil, the oil-soluble nutrient and the oil-based emulsifier, then adding the aqueous nutrient core into the obtained oily nutrient, and carrying out first homogenization treatment on the obtained mixture;
(3) and (3) carrying out third mixing on the composite wall material, the water-based emulsifier and water to obtain a water-based wall material, then adding the material subjected to the homogenization treatment in the step (2) into the obtained water-based wall material, and carrying out second homogenization treatment on the obtained mixture to obtain the fish collagen peptide composite nutrition bag.
8. The production method according to claim 7, wherein the pressure of the first homogenization treatment is 20 to 60 MPa;
preferably, the pressure of the second homogenization treatment is 20-30 MPa;
preferably, the first homogenization treatment comprises a first-stage homogenization and a second-stage homogenization, wherein the pressure of the first-stage homogenization is 20-30MPa, and the pressure of the second-stage homogenization is 40-60 MPa.
9. The production method according to claim 7 or 8, wherein the second mixing is performed under heating, preferably at a temperature of 60-70 ℃;
preferably, the third mixing is carried out under heating, preferably at a temperature of 70-80 ℃.
10. A fish collagen peptide complex nutritional package prepared by the method of any one of claims 7 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010238340.3A CN111317144A (en) | 2020-03-30 | 2020-03-30 | Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010238340.3A CN111317144A (en) | 2020-03-30 | 2020-03-30 | Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111317144A true CN111317144A (en) | 2020-06-23 |
Family
ID=71167888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010238340.3A Pending CN111317144A (en) | 2020-03-30 | 2020-03-30 | Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111317144A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114794488A (en) * | 2022-04-14 | 2022-07-29 | 江南大学 | W/O/W emulsion suitable for entrapping free amino acid |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904507A (en) * | 2009-06-04 | 2010-12-08 | 上海久健生物科技发展有限公司 | Ferrous bisglycinate chelate nutritional composition and application thereof |
| CN104187711A (en) * | 2014-07-30 | 2014-12-10 | 广东省农业科学院蚕业与农产品加工研究所 | Intacted protein and short peptide compound type special-dietary nutritional emulsion of clinic patients and preparation method of intacted protein and short peptide compound type special-dietary nutritional emulsion |
| WO2014210326A2 (en) * | 2013-06-28 | 2014-12-31 | Cargill, Incorporated | Stable beverage and liquid food products and process for making such |
| CN105341902A (en) * | 2015-09-24 | 2016-02-24 | 无限极（中国）有限公司 | Edible protein, fat and polypeptide composition and self-assembling method thereof |
| CN110353145A (en) * | 2019-08-14 | 2019-10-22 | 上海首源生物技术有限公司 | A kind of multi-component nutrients solid beverage and preparation method thereof |
-
2020
- 2020-03-30 CN CN202010238340.3A patent/CN111317144A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904507A (en) * | 2009-06-04 | 2010-12-08 | 上海久健生物科技发展有限公司 | Ferrous bisglycinate chelate nutritional composition and application thereof |
| WO2014210326A2 (en) * | 2013-06-28 | 2014-12-31 | Cargill, Incorporated | Stable beverage and liquid food products and process for making such |
| CN104187711A (en) * | 2014-07-30 | 2014-12-10 | 广东省农业科学院蚕业与农产品加工研究所 | Intacted protein and short peptide compound type special-dietary nutritional emulsion of clinic patients and preparation method of intacted protein and short peptide compound type special-dietary nutritional emulsion |
| CN105341902A (en) * | 2015-09-24 | 2016-02-24 | 无限极（中国）有限公司 | Edible protein, fat and polypeptide composition and self-assembling method thereof |
| CN110353145A (en) * | 2019-08-14 | 2019-10-22 | 上海首源生物技术有限公司 | A kind of multi-component nutrients solid beverage and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 杨晓慧等: "新型粉末油脂的制备", 《中国油脂》 * |
| 陈华等: "海洋胶原蛋白肽的制备及生物活性研究进展", 《中国食物与营养》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114794488A (en) * | 2022-04-14 | 2022-07-29 | 江南大学 | W/O/W emulsion suitable for entrapping free amino acid |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Stortz et al. | Edible oleogels in food products to help maximize health benefits and improve nutritional profiles | |
| CN102972671B (en) | Nano-scale food carrier preparation method based on polysaccharide-protein composite aggregate | |
| CN103445169B (en) | Instant germ mixing powder and preparation method thereof | |
| Kouamé et al. | Novel trends and opportunities for microencapsulation of flaxseed oil in foods: A review | |
| KR101156789B1 (en) | Composition for gelatin film, gelatin film, and capsule made with the same | |
| CN104622921B (en) | A kind of preparation method of granada seed oil microcapsules and its granada seed oil microcapsules | |
| CN101214046A (en) | Method for preparing ginkgo biloba oil powder | |
| CN105434319B (en) | A kind of cosmetics and preparation method thereof based on phaffiafhodozyma raw material | |
| CN106916871A (en) | A kind of bionic enzymatic prepares the production method of freshwater mussel meat small peptide | |
| CN111466575A (en) | Preparation method of functional composite protein emulsion gel | |
| Apostol | Studies on using hemp seed as functional ingredient in the production of functional food products. | |
| CN111317144A (en) | Fish collagen small molecule peptide composite nutrition bag capable of directly reaching small intestine and preparation method thereof | |
| Rossi et al. | Bioactive ingredients obtained from agro-industrial byproducts: recent advances and innovation in micro-and nanoencapsulation | |
| CN107353664A (en) | A kind of edible packing membrane based on sargassan | |
| CN112042937B (en) | Water-soluble lutein emulsion gel and preparation method thereof | |
| CN101347223B (en) | Cordyceps sinensis potato nutritional vermicelli | |
| CN106937680A (en) | A kind of walnut oil and water soluble powder powder composition and preparation method thereof | |
| CN113940431A (en) | Preparation method of vegetable proteoglycan microcapsule embedding functional grease | |
| CN115969036B (en) | Plant sterol particles and preparation method thereof | |
| Han et al. | Current research on the extraction, functional properties, interaction with polyphenols, and application evaluation in delivery systems of aquatic-based proteins | |
| KR20090077098A (en) | Enzymatic extracts, its formulated pill from eisenia bicyclis for lowering blood lipid and glucose, and a preparation method thereof | |
| Sha et al. | The prolamins, from structure, property, to the function in encapsulation and delivery of bioactive compounds | |
| CN115644453A (en) | Method for stabilizing DHA emulsion by soybean polypeptide-polyphenol antioxidant particles | |
| CN102805288A (en) | Extraction method for rice bran nutriments | |
| JP2002235084A (en) | Antioxidant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |