CN111266025B - Solid medicament dissolving and mixing device for pharmaceutical research - Google Patents

Solid medicament dissolving and mixing device for pharmaceutical research Download PDF

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Publication number
CN111266025B
CN111266025B CN202010200037.4A CN202010200037A CN111266025B CN 111266025 B CN111266025 B CN 111266025B CN 202010200037 A CN202010200037 A CN 202010200037A CN 111266025 B CN111266025 B CN 111266025B
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mixing
medicament
plate
motor
rotary
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CN111266025A (en
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张君
邵光波
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00Mixers with rotating receptacles
    • B01F29/10Mixers with rotating receptacles with receptacles rotated about two different axes, e.g. receptacles having planetary motion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00Dissolving
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00Dissolving
    • B01F21/10Dissolving using driven stirrers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/443Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a superposed additional movement other than oscillation, vibration or shaking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/81Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/813Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles mixing simultaneously in two or more mixing receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/82Combinations of dissimilar mixers
    • B01F33/821Combinations of dissimilar mixers with consecutive receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Accessories For Mixers (AREA)

Abstract

The invention discloses a solid medicament dissolving and mixing device for pharmaceutical research, which comprises a mounting rack, a medicament dissolving component and a medicament mixing component, wherein the mounting rack comprises a bottom plate and a supporting plate, the supporting plate is arranged on the bottom plate, the medicament dissolving component comprises a rotary box, a medicament pipe, a first motor and a second motor, the rotary box is provided with a gear ring and a rotary jacket, the rotary jacket is connected with the supporting plate, the rotary box is provided with an end cover, the end cover is provided with a clamping groove and a liquid discharging component, the medicament pipe is in threaded connection with the end cover, the first motor is used for driving the rotary box to rotate on a horizontal plane, the second motor is used for driving the rotary box to vertically turn over, the medicament mixing component comprises a mixing cylinder and a stirring component, the bottom plate of the mixing cylinder is movably connected, the mixing cylinder is provided with a contact for opening the liquid discharging component, the stirring component is movably arranged in the mixing cylinder, and the stirring component is used for stirring medicaments; the invention has reasonable structural design, can quickly dissolve solid medicament and mix a plurality of medicaments, and is suitable for large-scale popularization.

Description

Solid medicament dissolving and mixing device for pharmaceutical research
Technical Field
The invention relates to the technical field of pharmaceutical research equipment, in particular to a solid medicament dissolving and mixing device for pharmaceutical research.
Background
Pharmacy is the crystal of the public wisdom of people of all ages, and has great contribution to the health development, ethnic reproduction and development of the whole human. The traditional Chinese medicine has long-running sources, is a treasure in excellent cultural heritage of Chinese nationality, and is one of the unique advantages of China in modern international communication.
In clinical pharmaceutical research experiments, solid medicaments need to be dissolved so as to research and analyze various components in the medicaments, and various medicaments need to be mixed so as to research the reaction effect of the medicaments; however, most of the currently adopted solid drug dissolving devices are that after a solid medicament is added into a conical flask, an experimenter manually vibrates to accelerate dissolution, and such an operation mode is very inconvenient for pharmaceutical research and experiment processes with frequent operation, increases the work difficulty for medical staff and reduces the pharmaceutical experiment efficiency; meanwhile, the existing medicament mixing operation is to dissolve the medicament and then transfer the medicament to a mixing device for stirring and mixing, so that the number of experimental equipment is increased, and the efficiency of pharmaceutical research experiments is reduced.
Disclosure of Invention
In view of the above-mentioned problems, the present invention provides a solid pharmaceutical preparation dissolving and mixing device for pharmaceutical research, which can rapidly dissolve a solid pharmaceutical preparation.
The technical scheme of the invention is as follows: a solid medicament dissolving and mixing device for pharmaceutical research comprises a mounting rack, a medicament dissolving component and a medicament mixing component; the mounting frame comprises a bottom plate and two support plates, the two support plates are vertically and fixedly arranged on the bottom plate respectively, and shaft sleeves are arranged at the upper ends of the two support plates; the chemical dissolving assembly comprises a rotary box, a chemical tube, a first motor and a second motor, wherein a gear ring and a rotary jacket are sleeved on the outer wall of the rotary box, the gear ring is fixedly connected with the rotary box, the rotary jacket is positioned at the lower end of the gear ring and is positioned in the middle of the rotary box, the rotary jacket is rotatably clamped with the rotary box, connecting shafts are fixedly arranged at two ends of the rotary jacket, the rotary jacket is movably connected with two shaft sleeves through the connecting shafts respectively, one of the connecting shafts is provided with a rotary belt wheel, a placing cavity is arranged in the rotary box, the upper end of the rotary box is provided with an end cover, the end cover is fixedly connected with the rotary box through a bolt, the upper end of the end cover is provided with a clamping groove and a liquid discharging assembly, the lower end of the end cover is provided with an inner thread groove, the liquid discharging assembly is communicated with the inner thread groove, and the positions of the liquid discharging assembly, the inner thread groove and the placing cavity are vertically corresponding; the drug tube is movably arranged in the placing cavity, an external thread is arranged at the upper end of the drug tube, the drug tube is in threaded connection with the internal thread groove through the external thread, the first motor is fixedly arranged on the other connecting shaft, a driving gear is arranged on an output shaft of the first motor, the driving gear is in meshed connection with the gear ring, the second motor is fixedly arranged on the bottom plate, a driving belt wheel is arranged on an output shaft of the second motor, and the driving belt wheel is connected with the rotating belt wheel through a belt; the medicament mixing assembly comprises a mixing barrel and a stirring assembly, two ends of the mixing barrel are fixedly connected with a bottom plate through electric telescopic rods respectively, the mixing barrel is positioned at the lower end of a rotary box, a trigger disc is arranged at the upper end of the mixing barrel, a contact is arranged on the trigger disc, the contact corresponds to the upper position and the lower position of the tapping assembly, the tapping assembly can be triggered to open by the contact, and a liquid distribution port and a discharge port are formed in the side wall of the mixing barrel; the stirring subassembly activity sets up inside the mixing drum, and the stirring subassembly is used for stirring the medicament.
The liquid discharging assembly comprises a liquid discharging pipe and a sealing plate, a boss is arranged at the upper end of the liquid discharging pipe, a fixing frame is arranged at the joint of the liquid discharging pipe and the end cover, the sealing plate is connected with the fixing frame through a sleeve, the upper end of the sealing plate is clamped with the boss, a rubber sealing ring is arranged at the upper end of the sealing plate, a reset spring is sleeved on the sleeve, the upper end of the reset spring is abutted against the sleeve, and the lower end of the reset spring is abutted against the fixing frame; during the use, make the rotary box be in and lead to the state, the mixing drum rises under electric telescopic handle's effect, triggers contact on the dish and with closing plate jack-up for the medicament after dissolving in the medicament pipe is released and is mixed in the mixing drum, has improved the convenience of device operation.
Further, the stirring subassembly includes the mixing plate, rotatory fan board and positive reverse motor, the mixing plate activity sets up inside the mixing drum, evenly there are a plurality of through-holes on the mixing plate, the vertical mounting panel that is provided with in mixing plate upper end, the rotatable joint of rotatory fan board level is on the mounting panel, positive reverse motor is fixed to be set up in mixing drum outside bottom, be provided with the threaded rod on the output shaft of positive reverse motor, the threaded rod runs through the mixing drum bottom, and with mixing plate threaded connection, through setting up mixing plate and rotatory fan board, the mixing plate is under the effect of positive reverse motor and threaded rod, reciprocate in the mixing drum is inside, the medicament constantly falls through-hole on through the mixing plate, rotatory fan board is the transmission of the reflection of in-process at the mixing plate simultaneously, the mixed effect of various medicaments has been promoted.
Furthermore, 4-8 placing cavities are arranged, the liquid discharging assemblies, the medicament tubes, the contacts and the placing cavities are consistent in number and are in one-to-one correspondence with each other in the upper position and the lower position, and the 4-8 placing cavities are arranged, so that various solid medicaments can be dissolved simultaneously, the mixing among various medicaments is facilitated, and the working efficiency is greatly improved.
Furthermore, an arc-shaped clamping plate is arranged in the placing cavity through a spring rod, a plurality of melting-assisting bulges are uniformly arranged on the inner wall of the medicament tube, and the medicament tube is prevented from being damaged due to collision with the placing cavity in the rotating process of the rotating box through the arc-shaped clamping plate; through setting up and helping the arch of melting for solid medicament dissolves the in-process and helps the protruding continuous collision of melting, improves solid medicament's dissolution efficiency.
Further, be provided with transparent window on the rotatory case, be provided with the scale sign on the transparent window, through setting up transparent window and scale sign, be convenient for control the addition of solvent in the medicament pipe.
Furthermore, the lower end of the bottom plate is provided with a shock-proof pad; through setting up the vibration stopping pad, reduced the noise that the device operation in-process produced because vibrations greatly, be favorable to improving experimental environment quality.
The working principle of the invention is as follows: when the rotary box is used, solid medicaments to be dissolved and mixed are placed into a medicament tube, a quantitative solvent is added into the medicament tube, then the medicament tube is fixed on an inner thread groove of an end cover, finally the medicament tube and the end cover are inserted into a placing cavity of the rotary box together, the medicament tube is clamped and fixed through an arc-shaped clamping plate arranged in the placing cavity, and the end cover and the rotary box are fixed through bolts; the first motor and the second motor are driven by an external power supply device to be started simultaneously, the first motor and the second motor drive the rotary box to rotate on a horizontal plane and a vertical plane simultaneously, the dissolved state of the solid medicament in the medicament tube is observed through the transparent window 205, after the solid medicament is dissolved, the first motor and the second motor stop running, and the rotary box is adjusted to be in an inverted state; the electric telescopic rod drives the mixing cylinder to ascend, the upper edge of the mixing cylinder is buckled with a clamping groove in the end cover, the contact on the trigger disc jacks up the sealing plate at the moment, so that the medicament dissolved in the medicament tube is released into the mixing cylinder through the liquid discharge tube, the mixing plate moves up and down in the mixing cylinder under the action of the forward and reverse rotating motor and the threaded rod, the medicament continuously falls through a through hole in the mixing plate, and meanwhile, the rotating fan plate reversely and automatically transmits in the moving process of the mixing plate, so that the dissolved medicament is quickly mixed; in the medicament mixing process, a solvent is added into the mixing cylinder through the liquid distribution port, and the mixed medicament is discharged and collected through the discharge port.
Compared with the prior art, the invention has the beneficial effects that: the invention has reasonable structural design, greatly improves the dissolving and mixing efficiency of the solid medicament, reduces the workload of scientific research personnel and improves the working efficiency; according to the invention, the two motors are arranged, so that the rotary box can rotate on the horizontal surface and the vertical surface, and meanwhile, the melting-assisting bulge is arranged in the medicament tube, so that the solid medicament and the melting-assisting bulge continuously collide in the rotation process of the medicament tube along with the rotary box, and the dissolving efficiency of the solid medicament is greatly improved; meanwhile, the rotary box rotates in two dimensions, so that solid medicaments can be prevented from being bonded on the reagent tube after being dissolved, and the accuracy of a pharmaceutical experiment result is improved; by the medicament mixing assembly, different types of medicaments can be uniformly mixed, and the phenomenon of nonuniform medicament mixing caused by a single mixing mode is avoided.
Drawings
FIG. 1 is a schematic view of the internal structure of the present invention;
FIG. 2 is a left side view of the present invention;
FIG. 3 is a top view of the present invention;
FIG. 4 is a schematic view of the connection of the drug tube of the present invention to the rotary case;
FIG. 5 is a schematic view of the connection of the tapping assembly of the present invention to an end cap;
FIG. 6 is a schematic view of the internal structure of the mixing drum of the present invention;
wherein, 1-mounting rack, 10-bottom plate, 11-support plate, 110-shaft sleeve, 2-medicament dissolving component, 20-rotating box, 200-gear ring, 201-rotating jacket, 2010-connecting shaft, 2011-rotating belt wheel, 202-placing cavity, 203-spring rod, 204-arc splint, 205-transparent window, 21-medicament tube, 210-melting assisting protrusion, 22-first motor, 220-driving gear, 23-second motor, 230-driving belt wheel, 231-belt, 24-end cover, 240-bolt, 241-inner thread groove, 25-liquid discharging component, 250-liquid discharging tube, 2500-boss, 2501-fixing rack, 251-sealing plate, 2510-sleeve, 2511-rubber sealing ring, 2512-return spring, 3-medicament mixing component, 30-mixing cylinder, 300-electric telescopic rod, 301-trigger plate, 302-contact, 303-liquid distribution port, 304-discharge port, 31-stirring component, 310-mixing plate, 3100-through hole, 3101-mounting plate, 311-rotating fan plate, 312-positive and negative rotating motor, 3120-threaded rod.
Detailed Description
Example (b): fig. 1 and 2 show a solid medicine dissolving and mixing device for pharmaceutical research, which comprises a mounting frame 1, a medicine dissolving component 2 and a medicine mixing component 3; the mounting rack 1 comprises a bottom plate 10 and a supporting plate 11, and a shock-proof pad is arranged at the lower end of the bottom plate 10; by arranging the vibration stopping pad, the noise generated by vibration in the running process of the device is greatly reduced, and the quality of the experimental environment is favorably improved; two support plates 11 are arranged, the two support plates 11 are respectively vertically and fixedly arranged on the bottom plate 10, and the upper ends of the two support plates 11 are respectively provided with a shaft sleeve 110;
as shown in fig. 1, 2, 3, 4, and 5, the chemical dissolving assembly 2 includes a rotary box 20, a chemical tube 21, a first motor 22, and a second motor 23, a gear ring 200 and a rotary jacket 201 are sleeved on an outer wall of the rotary box 20, the gear ring 200 and the rotary jacket 20 are fixedly connected, the rotary jacket 201 is located at a lower end of the gear ring 200 and is located in a middle portion of the rotary box 20, the rotary jacket 201 and the rotary box 20 are rotatably clamped, connecting shafts 2010 are fixedly disposed at two ends of the rotary jacket 201, the rotary jacket 201 is movably connected to the two shaft sleeves 110 through the connecting shafts 2010, one of the connecting shafts 2010 is provided with a rotary pulley 2011, placing cavities 202 are disposed inside the rotary box 20, the placing cavities 202 are provided with 5, the liquid discharging assemblies 25, the chemical tubes 21, the contacts 302, and the placing cavities 202 are in corresponding numbers, and the top and bottom positions are in one-to-one correspondence, by providing 5 placing cavities 202, a plurality of solid chemicals can be dissolved simultaneously, meanwhile, the mixing of various medicaments is facilitated, and the working efficiency is greatly improved; an arc-shaped clamping plate 204 is arranged in the placing cavity 202 through a spring rod 203, a plurality of melting-assisting protrusions 210 are uniformly arranged on the inner wall of the medicine tube 21, and the medicine tube 21 is prevented from being damaged due to collision with the placing cavity 202 in the rotating process of the rotating box 20 through the arc-shaped clamping plate 204; the melting-assisting projection 210 is arranged, so that the solid medicament continuously collides with the melting-assisting projection 210 in the dissolving process, and the dissolving efficiency of the solid medicament is improved; the transparent window 205 is arranged on the rotary box 20, the scale marks are arranged on the transparent window 205, and the addition amount of the solvent in the medicament tube 21 can be conveniently controlled by arranging the transparent window 205 and the scale marks; an end cover 24 is arranged at the upper end of the rotary box 20, the end cover 24 is fixedly connected with the rotary box 20 through a bolt 240, a clamping groove and a liquid discharging assembly 25 are arranged at the upper end of the end cover 24, an internal thread groove 241 is arranged at the lower end of the end cover 24, the liquid discharging assembly 25 is communicated with the internal thread groove 241, and the liquid discharging assembly 25, the internal thread groove 241 and the placing cavity 202 are vertically corresponding in position; the liquid discharging assembly 25 comprises a liquid discharging pipe 250 and a sealing plate 251, a boss 2500 is arranged at the upper end of the liquid discharging pipe 250, a fixing frame 2501 is arranged at the joint of the liquid discharging pipe 250 and the end cover 24, the sealing plate 251 is connected with the fixing frame 2501 through a sleeve 2510, the upper end of the sealing plate 251 is clamped with the boss 2500, a rubber sealing ring 2511 is arranged at the upper end of the sealing plate 251, a reset spring 2512 is sleeved on the sleeve 2510, the upper end of the reset spring 2512 is abutted against the sleeve 2510, and the lower end of the reset spring 2512 is abutted against the fixing frame 2501; when the device is used, the rotating box 20 is in a leading state, the mixing cylinder 30 rises under the action of the electric telescopic rod 300, the contact 302 on the trigger disc 301 jacks up the sealing plate 251, so that the medicament dissolved in the medicament tube 21 is released into the mixing cylinder 30 to be mixed, and the convenience of the operation of the device is improved; the medicine tube 21 is movably arranged in the placing cavity 202, an external thread is arranged at the upper end of the medicine tube 21, the medicine tube 21 is in threaded connection with the internal thread groove 241 through the external thread, the first motor 22 is fixedly arranged on the other connecting shaft 2010, a driving gear 220 is arranged on an output shaft of the first motor 22, the driving gear 220 is in meshed connection with the gear ring 200, the second motor 23 is fixedly arranged on the bottom plate 10, a driving belt wheel 230 is arranged on an output shaft of the second motor 23, and the driving belt wheel 230 is connected with the rotating belt wheel 2011 through a belt 231; the first motor 22 and the second motor 23 both adopt ZD type three-phase asynchronous motors produced by Shandong power king heavy industry machinery, Inc., and the first motor 22 and the second motor 23 are both powered by external power supplies;
as shown in fig. 1, 2 and 6, the medicine mixing assembly 3 comprises a mixing cylinder 30 and a stirring assembly 31, two ends of the mixing cylinder 30 are respectively and fixedly connected with the bottom plate 10 through electric telescopic rods 300, and the mixing cylinder is an XTL type electric push rod produced by the technical manufacturing factory; a trigger disc 301 is arranged at the upper end of the mixing cylinder 30, a contact 302 is arranged on the trigger disc 301, the contact 302 corresponds to the upper and lower positions of the tapping component 25, the contact 302 can trigger the tapping component 25 to be opened, and a liquid distribution port 303 and a discharge port 304 are arranged on the side wall of the mixing cylinder 30; the stirring component 31 comprises a mixing plate 310, a rotating fan plate 311 and a forward and reverse rotating motor 312, the mixing plate 310 is movably arranged inside the mixing cylinder 30, a plurality of through holes 3100 are uniformly arranged on the mixing plate 310, a mounting plate 3101 is vertically arranged at the upper end of the mixing plate 310, the rotating fan plate 311 is horizontally and rotatably clamped on the mounting plate 3101, the forward and reverse rotating motor 312 is fixedly arranged at the bottom end outside the mixing cylinder 30, the forward and reverse rotating motor 312 adopts a 5IK120GN-C type forward and reverse rotating micro large torque motor produced by Xinda motor Limited company, a threaded rod 3120 is arranged on an output shaft of the forward and reverse rotating motor 312, the threaded rod 3120 penetrates through the bottom of the mixing cylinder 30 and is in threaded connection with the mixing plate 310, through the arrangement of the mixing plate 310 and the rotating fan plate 311, the mixing plate 310 moves up and down inside the mixing cylinder 30 under the action of the forward and reverse rotating motor 312 and the threaded rod 3120, the medicament continuously falls through the through holes 3100 on the mixing plate 310, meanwhile, the rotating fan plate 311 is transmitted by itself during the moving process of the mixing plate 310, so that the mixing effect of various medicaments is promoted.
When the device is used, solid medicaments needing to be dissolved and mixed are placed into the medicament tube 21, a quantitative solvent is added into the medicament tube 21, then the medicament tube 21 is fixed on the internal thread groove 241 of the end cover 24, finally the medicament tube 21 and the end cover 24 are inserted into the placing cavity 202 of the rotary box 20 together, the medicament tube 21 is clamped and fixed through the arc-shaped clamping plate 204 arranged in the placing cavity 202, and the end cover 24 and the rotary box 20 are fixed through the bolt 240; the first motor 22 and the second motor 23 are driven by an external power supply device to be started simultaneously, the first motor 22 and the second motor 23 drive the rotary box 20 to rotate on the horizontal plane and the vertical plane simultaneously, the dissolved state of the solid medicament in the medicament tube 21 is observed through the transparent window 205, after the solid medicament is dissolved, the first motor 22 and the second motor 23 stop running, and the rotary box 20 is adjusted to be in an inverted state; the electric telescopic rod 300 drives the mixing cylinder 30 to ascend, the upper edge of the mixing cylinder 30 is buckled with a clamping groove in the end cover 24, at the moment, the contact 302 on the trigger disc 301 jacks up the sealing plate 251, so that the medicament dissolved in the medicament tube 21 is released into the mixing cylinder 30 through the liquid discharge tube 250, the mixing plate 310 moves up and down in the mixing cylinder 30 under the action of the forward and reverse rotating motor 312 and the threaded rod 3120, the medicament continuously falls through a through hole 3100 in the mixing plate 310, and meanwhile, the rotating fan plate 311 is reversely and automatically transmitted in the moving process of the mixing plate 310, so that the dissolved medicament is quickly mixed; in the process of mixing the medicaments, the solvent is added into the mixing cylinder 30 through the liquid distribution port 303, and the mixed medicaments are discharged and collected through the discharge port 304.

Claims (1)

1. A solid medicament dissolving and mixing device for pharmaceutical research is characterized by comprising a mounting rack (1), a medicament dissolving component (2) and a medicament mixing component (3); the mounting frame (1) comprises a bottom plate (10) and two supporting plates (11), the two supporting plates (11) are vertically and fixedly arranged on the bottom plate (10) respectively, and shaft sleeves (110) are arranged at the upper ends of the two supporting plates (11); the medicament dissolving assembly (2) comprises a rotary box (20), a medicament tube (21), a first motor (22) and a second motor (23), wherein a gear ring (200) and a rotary jacket (201) are sleeved on the outer wall of the rotary box (20), the gear ring (200) and the rotary box (20) are fixedly connected, the rotary jacket (201) is positioned at the lower end of the gear ring (200) and in the middle of the rotary box (20), the rotary jacket (201) and the rotary box (20) are rotatably clamped, connecting shafts (2010) are fixedly arranged at two ends of the rotary jacket (201), the rotary jacket (201) is movably connected with two shaft sleeves (110) through the connecting shafts (2010), one of the connecting shafts (2010) is provided with a rotary belt wheel (2011), a placing cavity (202) is arranged inside the rotary box (20), and an end cover (24) is arranged at the upper end of the rotary box (20), the end cover (24) is fixedly connected with the rotary box (20) through a bolt (240), a clamping groove and a liquid discharging assembly (25) are arranged at the upper end of the end cover (24), an internal thread groove (241) is arranged at the lower end of the end cover (24), the liquid discharging assembly (25) is communicated with the internal thread groove (241), and the positions of the liquid discharging assembly (25), the internal thread groove (241) and the placing cavity (202) correspond up and down; the medicine tube (21) is movably arranged in the placing cavity (202), an external thread is arranged at the upper end of the medicine tube (21), the medicine tube (21) is in threaded connection with the internal thread groove (241) through the external thread, the first motor (22) is fixedly arranged on the other connecting shaft (2010), a driving gear (220) is arranged on an output shaft of the first motor (22), the driving gear (220) is in meshed connection with the gear ring (200), the second motor (23) is fixedly arranged on the bottom plate (10), a driving belt wheel (230) is arranged on an output shaft of the second motor (23), and the driving belt wheel (230) is connected with the rotating belt wheel (2011) through a belt (231); the medicament mixing assembly (3) comprises a mixing barrel (30) and a stirring assembly (31), two ends of the mixing barrel (30) are fixedly connected with a bottom plate (10) through electric telescopic rods (300) respectively, the mixing barrel (30) is located at the lower end of a rotary box (20), a trigger disc (301) is arranged at the upper end of the mixing barrel (30), a contact (302) is arranged on the trigger disc (301), the contact (302) corresponds to the liquid discharging assembly (25) in the vertical position, the contact (302) can trigger the liquid discharging assembly (25) to be opened, and a liquid distribution port (303) and a discharge port (304) are formed in the side wall of the mixing barrel (30); the stirring component (31) is movably arranged in the mixing cylinder (30), and the stirring component (31) is used for stirring the medicament;
the liquid discharging assembly (25) comprises a liquid discharging pipe (250) and a sealing plate (251), a boss (2500) is arranged at the upper end of the liquid discharging pipe (250), a fixing frame (2501) is arranged at the joint of the liquid discharging pipe (250) and the end cover (24), the sealing plate (251) is connected with the fixing frame (2501) through a sleeve (2510), the upper end of the sealing plate (251) is clamped with the boss (2500), a rubber sealing ring (2511) is arranged at the upper end of the sealing plate (251), a return spring (2512) is sleeved on the sleeve (2510), the upper end of the return spring (2512) is abutted against the sleeve (2510), and the lower end of the return spring is abutted against the fixing frame (2501);
the stirring assembly (31) comprises a mixing plate (310), a rotating fan plate (311) and a forward and reverse rotating motor (312), wherein the mixing plate (310) is movably arranged inside the mixing cylinder (30), a plurality of through holes (3100) are uniformly formed in the mixing plate (310), an installation plate (3101) is vertically arranged at the upper end of the mixing plate (310), the rotating fan plate (311) is horizontally and rotatably clamped on the installation plate (3101), the forward and reverse rotating motor (312) is fixedly arranged at the bottom end of the outer part of the mixing cylinder (30), a threaded rod (3120) is arranged on an output shaft of the forward and reverse rotating motor (312), and the threaded rod (3120) penetrates through the bottom of the mixing cylinder (30) and is in threaded connection with the mixing plate (310);
4-8 placing cavities (202) are arranged, the liquid discharging assemblies (25), the medicament tubes (21), the contacts (302) and the placing cavities (202) are in corresponding consistency in number, and the upper positions and the lower positions are in one-to-one correspondence;
an arc-shaped clamping plate (204) is arranged in the placing cavity (202) through a spring rod (203), and a plurality of melting-assisting bulges (210) are uniformly arranged on the inner wall of the medicament tube (21);
a transparent window (205) is arranged on the rotary box (20), and a scale mark is arranged on the transparent window (205);
the liquid discharging assembly (25), the medicament tube (21), the contact (302) and the placing cavity (202) are provided with 4-8 liquid discharging assemblies.
CN202010200037.4A 2020-03-20 2020-03-20 Solid medicament dissolving and mixing device for pharmaceutical research Active CN111266025B (en)

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Application Number Priority Date Filing Date Title
CN202010200037.4A CN111266025B (en) 2020-03-20 2020-03-20 Solid medicament dissolving and mixing device for pharmaceutical research

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Application Number Priority Date Filing Date Title
CN202010200037.4A CN111266025B (en) 2020-03-20 2020-03-20 Solid medicament dissolving and mixing device for pharmaceutical research

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CN111266025A CN111266025A (en) 2020-06-12
CN111266025B true CN111266025B (en) 2022-01-25

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CN112206666A (en) * 2020-10-12 2021-01-12 陈东伟 Solid medicament dissolving and mixing device for pharmaceutical research
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