CN111260610B - Anterior segment state characterization method and system based on atrial angle open distance curve - Google Patents
Anterior segment state characterization method and system based on atrial angle open distance curve Download PDFInfo
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Abstract
The invention discloses a method and a system for representing the state of anterior ocular segment based on an atrial angle open distance curve, wherein the method comprises the following steps: s1, extracting a distance value change curve between the back surface of a cornea and the front surface of an iris by using an anterior segment section image of the eye to obtain an angle opening distance curve; s2, obtaining eye parameters according to an atrial angle opening distance curve; s3, judging the state of the anterior segment of the eye according to the eye parameters. The system comprises an AOD curve extraction module and a state characterization module of the anterior ocular segment, wherein the AOD curve extraction module is used for extracting a distance value change curve between the cornea back surface and the iris front surface, namely an AOD curve, according to the anterior ocular segment tangent plane image; the state characterization module of the anterior ocular segment is used for judging the state of the anterior ocular segment according to various parameter values of the AOD curve. The method is simple, the curve precision is high, the eye parameters are obtained based on the AOD curve, the focus is found in time, and a more accurate basis is provided for eye examination.
Description
Technical Field
The invention relates to the technical field of ophthalmic parameter extraction, in particular to a method and a system for representing the state of anterior ocular segment based on an atrial angle open distance curve.
Background
With the popularization of electronic products, modern people are filled with various display screen electronic devices, eyes of people can be in a tired state when the electronic products are used for a long time, and various ophthalmic diseases can be induced if the electronic products are not good at adjustment. The most common ophthalmic diseases generally occur at the anterior ocular segment position, and a doctor is required to collect the state parameters of the anterior ocular segment of a patient through equipment, judge the eye state according to the eye parameters, and find a focus.
Therefore, how to accurately extract the anterior segment position parameters provides a basis for analyzing the eye state and judging, which is a problem to be solved urgently.
Disclosure of Invention
The invention aims to provide a method and a system for representing the state of anterior ocular segment based on an angular opening distance curve, which are used for obtaining a corneal back surface and an iris front surface based on an anterior ocular segment section image, obtaining an angular opening distance curve from a distance change curve between the corneal back surface and the iris front surface, and obtaining ocular parameters on the curve for eye examination. The method and the device realize the acquisition of high-precision eye parameters through simple steps, and provide basis for eye examination.
The above object of the present invention is achieved by the following technical solutions:
an anterior ocular segment state characterization method based on a corner of the house open distance curve comprises the following steps:
s1, extracting a distance value change curve between the back surface of a cornea and the front surface of an iris by using an anterior segment section image of the eye to obtain an angle opening distance curve;
s2, obtaining eye parameters according to an atrial angle opening distance curve;
s3, judging the state of the anterior segment of the eye according to the eye parameters.
The invention is further provided with: and (3) making a vertical line in the normal direction of each point on the back surface of the cornea, obtaining the length of the vertical line at the intersection of the vertical line and the front surface of the iris, and taking the length as the distance from each point on the back surface of the cornea to each corresponding point on the front surface of the iris, and obtaining the distance value between each point on the back surface of the cornea and each corresponding point on the front surface of the iris, thereby obtaining a normal room angle open distance curve.
The invention is further provided with: the method comprises the following steps:
a1, performing curve fitting on the cornea back surface of the acquired anterior ocular segment section image in a certain radial direction, filling the pupil area with the front surface of the crystal in the defect of the front surface of the iris, and fitting the supplemented front surface of the iris into a continuous curve serving as a fitting curve of the front surface of the iris;
a2, obtaining a normal line of any point on a fitting curve of the cornea back surface relative to the cornea back surface;
a3, making a vertical line along the normal direction, intersecting with the iris crystal line, and calculating the length of the intersection point of the cornea rear surface and the iris crystal line on the vertical line as the distance between the cornea rear surface and the iris crystal;
and A4, obtaining the distances from all points on the back surface of the cornea to corresponding points of the iris crystal respectively, and obtaining the radial cornea back surface normal angle opening distance curve.
The invention is further provided with: based on the central axis of the cornea back surface, the distance values between the cornea back surface and the iris front surface are extracted from parallel lines taking the central axis as the central axis from each point of the cornea back surface to each corresponding point of the iris front surface, and the distance value change curve of all points of the cornea back surface, namely the central axis room angle opening distance curve, is obtained.
The invention is further provided with: the method comprises the following steps:
b1, performing curve fitting on the cornea back surface of the acquired anterior ocular segment section image in a certain radial direction, filling the pupil area with the front surface of the crystal in the defect of the front surface of the iris, and fitting the supplemented front surface of the iris into a continuous curve serving as a fitting curve of the front surface of the iris;
b2, taking the central axis of symmetry of the rear surface of the cornea as a central axis;
b3, making a straight line parallel to the central axis from each point on the back surface of the cornea to an iris crystal line, wherein the distance from each point on the back surface of the cornea to the corresponding point of the iris crystal line is used as the distance between the back surface of the cornea and the iris crystal line;
and B3, obtaining the distances from all points on the back surface of the cornea to corresponding points of the iris crystal respectively, and obtaining the radial cornea back surface central axis atrial angle open distance curve.
The invention is further provided with: in step S2, according to the normal room angle opening distance curve, the following parameters are obtained: ARA, AOD500/AOD750, TISA500/TISA750, atrial angle, maximum anterior atrial depth, normal atrial depth map; and forming a three-dimensional normal room angle open distance curved surface based on the normal room angle open distance curves in different radial directions.
The invention is further provided with: in step S2, according to the central axis room angle opening distance curve, the following parameters are obtained: anterior chamber depth, anterior chamber width, anterior chamber volume; forming an anterior chamber depth map based on the chamber angle opening distance curves in different radial directions; based on the central shaft room angle open distance curves in different radial directions, a three-dimensional anterior chamber depth map is formed.
The invention is further provided with: in the optical coherence tomography image OCT or the ultrasound biomicroscopic image UBM, scleral spur is used as a starting point to serve as two side end points of an atrial-angle open distance curve.
The invention is further provided with: in step S3, the bending degree of the cornea relative to the iris is judged according to the slope of the atrial opening distance curve, and the anterior chamber pathological change condition is judged according to the bending degree.
The above object of the present invention is also achieved by the following technical solutions:
the anterior segment state representation system based on the room angle open distance curve comprises an AOD curve extraction module and an anterior segment state representation module, wherein the AOD curve extraction module is used for extracting a distance value change curve between the cornea back surface and the iris front surface, namely an AOD curve, according to an anterior segment tangent plane image; the state characterization module of the anterior ocular segment is used for judging the state of the anterior ocular segment according to various parameter values of the AOD curve.
Compared with the prior art, the invention has the beneficial technical effects that:
1. the method is simple and has high curve precision, and an angle of the house open distance (AOD) curve is obtained according to the distance value change curve between the two surfaces;
2. further, the obtained eye parameters can comprehensively represent the anterior segment state of the eye based on the AOD curve, and play an important role in timely finding out the focus;
3. further, the method and the device generate the 3D anterior chamber depth map by utilizing the AOD curves of the images of the plurality of radial anterior ocular segments, obtain the anterior chamber volume and provide more accurate basis for eye examination.
Drawings
FIG. 1 is a schematic illustration of the distance between the posterior surface of the cornea and the iris in the normal direction in accordance with an embodiment of the present invention;
FIG. 2 is a schematic view of the distance between the central axis cornea posterior surface and the iris in accordance with one embodiment of the invention;
fig. 3 is a schematic diagram of the distance between the left and right atrial corner endpoints based on AOD curves in accordance with an embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
The invention discloses an anterior ocular segment state characterization method based on an atrial angle open distance curve, which comprises the following steps:
s1, extracting a distance value change curve between the back surface of a cornea and the front surface of an iris by using an anterior segment section image of the eye to obtain an angle opening distance curve;
s2, obtaining eye parameters according to an atrial angle opening distance curve;
s3, judging the state of the anterior segment of the eye according to the eye parameters.
In step S1, the anterior segment cut image is used to extract the back surface of cornea and the front surface of iris, and the distance between the back surface of cornea and the front surface of iris is obtained to obtain the distance change curve, namely the curve of the angle of opening distance (AOD: angle Opening Distance).
In one embodiment of the present invention, as shown in fig. 1, a perpendicular is drawn in the normal direction at each point of the back surface 1 of the cornea, the length of the perpendicular 3 at the intersection of the perpendicular and the front surface 2 of the iris is obtained, and the distance between each point of the back surface of the cornea and each corresponding point of the front surface of the iris is obtained as the distance between each point of the back surface of the cornea and each corresponding point of the front surface of the iris, so as to obtain a normal angle opening distance curve.
Obtaining a normal room angle open distance curve, comprising the following steps:
a1, performing curve fitting on the cornea back surface of the acquired anterior ocular segment section image in a certain radial direction, filling the pupil area with the front surface of the crystal in the defect of the front surface of the iris, and fitting the supplemented front surface of the iris into a continuous curve serving as a fitting curve of the front surface of the iris;
a2, obtaining a normal line of any point on a fitting curve of the cornea back surface relative to the cornea back surface;
a3, making a vertical line along the normal direction, intersecting with the iris crystal line, and calculating the length of the intersection point of the cornea rear surface and the iris crystal line on the vertical line as the distance between the cornea rear surface and the iris crystal;
and A4, obtaining the distances from all points on the back surface of the cornea to corresponding points of the iris crystal respectively, and obtaining the radial cornea back surface normal angle opening distance curve.
In step S2, according to the normal room angle opening distance curve, the following parameters are obtained: ARA, AOD500/AOD750, TISA500/TISA750, atrial angle, maximum anterior atrial depth, normal atrial depth map; and forming a three-dimensional normal room angle open distance curved surface based on the normal room angle open distance curves in different radial directions.
The height of the AOD curve at the normal angle open distance curve is obtained at 500/750 microns (500/750 representing 500 microns or 750 microns) from both ends, said height being noted AOD500/750.
As shown in fig. 3, the distance 5 between the left and right atrial corner endpoints of the AOD curve is obtained.
In one embodiment of the present invention, based on the parallel lines 4 taking the central axis of the back surface of the cornea as the central axis from each point of the back surface 1 of the cornea to each corresponding point of the front surface 2 of the iris as shown in fig. 2, the distance values between the back surface of the cornea and the front surface of the iris are extracted, and the distance value change curve of all points of the back surface of the cornea, namely, the central axis angle opening distance curve, is obtained.
Acquiring a central shaft room angle opening distance curve: the method comprises the following steps:
b1, performing curve fitting on the cornea back surface of the acquired anterior ocular segment section image in a certain radial direction, filling the pupil area with the front surface of the crystal in the defect of the front surface of the iris, and fitting the supplemented front surface of the iris into a continuous curve serving as a fitting curve of the front surface of the iris;
b2, taking the central axis of symmetry of the rear surface of the cornea as a central axis;
b3, making a straight line parallel to the central axis from each point on the back surface of the cornea to an iris crystal line, wherein the distance from each point on the back surface of the cornea to the corresponding point of the iris crystal line is used as the distance between the back surface of the cornea and the iris crystal line;
and B3, obtaining the distances from all points on the back surface of the cornea to corresponding points of the iris crystal respectively, and obtaining the radial cornea back surface central axis atrial angle open distance curve.
In a specific embodiment of the present invention, in step S2, the following parameters are obtained according to the central axis atrial angle open distance curve: anterior chamber depth, anterior chamber width, anterior chamber volume; forming an anterior chamber depth map based on the chamber angle opening distance curves in different radial directions; based on the central shaft room angle open distance curves in different radial directions, a three-dimensional anterior chamber depth map is formed.
Based on the central axis room angle opening distance curve, the following parameters can be obtained:
selecting a section of AOD curve data of the cornea back surface, which is close to the scleral spur by 500 microns, and performing straight line fitting, wherein an included angle corresponding to the slope of the fitted straight line is the anterior chamber angle ACA
And (5) calculating the length of the central shaft room angle opening distance curve, wherein the length is the width of the anterior chamber.
And obtaining the maximum value of the open distance curve of the central shaft room angle, wherein the maximum value of the AOD curve is the anterior chamber depth.
Generating a 3D anterior chamber depth map according to the images of a plurality of radial lower anterior ocular segments at the same time and in a central shaft angle opening distance curve, and calculating to obtain anterior chamber volume ACV; wherein ACV represents anterior chamber volume (Anterior Chamber Volume).
In one embodiment of the present invention, in the optical coherence tomography image OCT or the ultrasound biomicroscopic image UBM, scleral spur is used as a starting point to be two side end points of the atrial-angular open distance curve.
In one embodiment of the present application, the degree of curvature of the iris relative to the cornea is determined based on the slope of the AOD curve and is used as a reference for determining anterior chamber lesions.
After obtaining the edge of the back surface of the cornea and the edge of the iris, a direct fit is made using a length of edge data to obtain the angle of the atrium, which is still 500/750 microns of data.
ACD represents anterior chamber depth (Anterior Chamber Depth) from AOD line including pupil area; the apex of the posterior surface of the cornea is at a distance from the crystal on the optical axis.
ACD map represents anterior chamber depth map (Anterior Chamber Depth map), comprising AOD lines of the crystal;
in one embodiment of the present application, in the optical coherence tomography image OCT or the ultrasound biomicroscopic image UBM, scleral spur is used as a starting point to be two side end points of the atrial-angle open distance curve.
In a specific embodiment of the present invention, in step S3, the degree of curvature of the cornea with respect to the iris is determined according to the slope of the curve of the open atrial angular distance, and the anterior atrial lesion is determined according to the degree of curvature.
In one embodiment of the present application, in the visible light anterior segment system, the intersection point of the fitted curve of the back surface of the cornea and the fitted curve of the back surface of the iris is the two side end points of the AOD curve.
In a specific embodiment of the application, the anterior ocular segment state characterization system based on the atrial angle open distance curve comprises an AOD curve extraction module and an anterior ocular segment state characterization module, wherein the AOD curve extraction module is used for extracting a distance value change curve between the cornea back surface and the iris front surface, namely an AOD curve, according to an anterior ocular segment section image by adopting a polar coordinate method or a Cartesian coordinate system; the state characterization module of the anterior ocular segment is used for judging the state of the anterior ocular segment according to various parameter values of the AOD curve.
The embodiments of the present invention are all preferred embodiments of the present invention, and are not intended to limit the scope of the present invention in this way, therefore: all equivalent changes in structure, shape and principle of the invention should be covered in the scope of protection of the invention.
Claims (9)
1. The anterior ocular segment state characterization method based on the atrial angle open distance curve is characterized by comprising the following steps of:
s1, extracting a fitting curve of a cornea back surface and a fitting curve of an iris front surface by utilizing an anterior segment tangent plane image, making a vertical line in a normal direction at each point of the cornea back surface, obtaining the length of the vertical line at the intersection of the vertical line and the iris front surface, obtaining distance values between each point of the cornea back surface and each corresponding point of the iris front surface, extracting a distance value change curve between each point of the cornea back surface and each corresponding point of the iris front surface, and obtaining a normal angle opening distance curve;
s2, obtaining eye parameters according to a normal room angle open distance curve;
s3, judging the state of the anterior segment of the eye according to the eye parameters.
2. The anterior ocular segment state characterization method based on the atrial angular opening distance curve of claim 1, comprising the steps of:
a1, performing curve fitting on the cornea back surface of the acquired anterior ocular segment section image in a certain radial direction, filling the pupil area with the front surface of the crystal in the defect of the front surface of the iris, and fitting the supplemented front surface of the iris into a continuous curve serving as a fitting curve of the front surface of the iris;
a2, obtaining a normal line of any point on a fitting curve of the cornea back surface relative to the cornea back surface;
a3, making a vertical line along the normal direction, intersecting with the iris crystal line, and calculating the length of the intersection point of the cornea rear surface and the iris crystal line on the vertical line as the distance between the cornea rear surface and the iris crystal;
and A4, obtaining the distances from all points on the back surface of the cornea to corresponding points of the iris crystal respectively, and obtaining the radial cornea back surface normal angle opening distance curve.
3. The anterior segment state characterization method based on the atrial angular opening distance curve according to claim 1, wherein in step S2, the following parameters are obtained according to the normal atrial angular opening distance curve: ARA, AOD500/AOD750, TISA500/TISA750, atrial angle, maximum anterior atrial depth, normal atrial depth map; and forming a three-dimensional normal room angle open distance curved surface based on the normal room angle open distance curves in different radial directions.
4. The anterior ocular segment state characterization method based on the atrial angle open distance curve is characterized by comprising the following steps of:
s1, extracting a fitting curve of the back surface of the cornea and a fitting curve of the front surface of the iris by utilizing an anterior segment section image of the eye, and extracting distance values between each point of the back surface of the cornea and each corresponding point of the front surface of the iris based on parallel lines taking the central axis of the back surface of the cornea as a reference and taking each point of the back surface of the cornea to each corresponding point of the front surface of the iris as a central axis, so as to obtain a distance value change curve of all points of the back surface of the cornea, namely a central axis room angle opening distance curve;
s2, obtaining eye parameters according to a central shaft room angle opening distance curve;
s3, judging the state of the anterior segment of the eye according to the eye parameters.
5. The anterior ocular segment state characterization method based on the atrial angular opening distance curve as claimed in claim 4, comprising the steps of:
b1, performing curve fitting on the cornea back surface of the acquired anterior ocular segment section image in a certain radial direction, filling the pupil area with the front surface of the crystal in the defect of the front surface of the iris, and fitting the supplemented front surface of the iris into a continuous curve serving as a fitting curve of the front surface of the iris;
b2, taking the central axis of symmetry of the rear surface of the cornea as a central axis;
b3, making a straight line parallel to the central axis from each point on the back surface of the cornea to an iris crystal line, wherein the distance from each point on the back surface of the cornea to the corresponding point of the iris crystal line is used as the distance between the back surface of the cornea and the iris crystal line;
and B3, obtaining the distances from all points on the back surface of the cornea to corresponding points of the iris crystal respectively, and obtaining the radial cornea back surface central axis atrial angle open distance curve.
6. The anterior ocular segment state characterization method based on the atrial angular opening distance curve of claim 4, wherein in step S2, the following parameters are obtained according to the central axis atrial angular opening distance curve: anterior chamber depth, anterior chamber width, anterior chamber volume; forming an anterior chamber depth map based on the chamber angle opening distance curves in different radial directions; based on the central shaft room angle open distance curves in different radial directions, a three-dimensional anterior chamber depth map is formed.
7. The anterior segment condition characterization method based on the atrial opening distance curve according to claim 1 or 4, wherein in the optical coherence tomography image OCT or the ultrasound biomicroscopic image UBM, scleral spur is used as both side end points of the atrial opening distance curve.
8. The anterior segment condition characterization method according to claim 1 or 4, wherein in step S3, the degree of curvature of the cornea with respect to the iris is determined according to the slope of the angular opening distance curve, and the anterior chamber lesion condition is determined according to the degree of curvature.
9. An anterior segment state representation system based on an anterior segment open-chamber distance curve is characterized by comprising an anterior segment open-chamber distance curve extraction module and an anterior segment state representation module, wherein the anterior segment open-chamber distance curve extraction module is used for extracting a distance value change curve between a cornea back surface and an iris front surface, namely an anterior segment open-chamber distance curve, according to an anterior segment tangent plane image by adopting the method of any one of claims 1-8; the state characterization module of the anterior ocular segment is used for judging the state of the anterior ocular segment according to various parameter values of the angular opening distance curve.
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| CN116342636B (en) * | 2023-05-23 | 2023-12-29 | 广东麦特维逊医学研究发展有限公司 | Eye anterior segment OCT image contour fitting method |
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| Association of biometric factors with anterior chamber angle widening and intraocular pressure reduction after uneventful phacoemulsification for cataract;Guofu Huang et al.;Journal of Cataract & Refractive Surgery;第38卷(第1期);全文 * |
| Effect of primary iris and ciliary body cyst on anterior chamber angle in patients with shallow anterior chamber;Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)(第09期);全文 * |
| 人工晶状体植入闭角型青光眼合并白内障患者的疗效观察;侯红超;苏小波;;华夏医学(第01期);全文 * |
| 前节OCT观察明暗光线下眼前节静态参数及其动态变化的研究;吴若欣;李金瑛;柯瑞莉;;眼科(第04期);全文 * |
| 眼前节相干光断层扫描在闭角型青光眼发病机制和临床分型诊断中的应用;张艳 等;现代中西医结合杂志;第27卷(第6期);全文 * |
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