CN104720740B - Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution - Google Patents

Abstract

The invention discloses and utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution, including: utilize slit-lamp to shoot cornea tangent plane crack figure；Cornea tangent plane crack figure is projected to cornea tangent plane, obtains cornea sectional drawing, on cornea sectional drawing, then find the forward and backward surface profile of cornea, obtain curvature distribution and the thickness distribution of cornea；Or first on the figure of cornea tangent plane crack, find the forward and backward surface profile of cornea, recycling cornea tangent plane crack figure projects to the coordinate conversion relation needed for cornea sectional drawing, the forward and backward surface profile of corneal carries out coordinate transform, obtain the forward and backward surface outline curves of the cornea on cornea sectional drawing, try to achieve curvature distribution and the thickness distribution of cornea.This method utilizes slit-lamp to shoot the cornea tangent plane crack figure obtained, cornea sectional drawing is obtained through image procossing, try to achieve thickness distribution and the curvature distribution of cornea according to cornea sectional drawing, widened the range of slit-lamp, help doctor to utilize slit-lamp to detect more fully human eye parameter.

Description

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution

Technical field

The invention belongs to slit-lamp technical applications, be specifically related to a kind of cornea recorded by slit-lamp and cut Facial cleft gap figure tries to achieve corneal curvature distribution and the method for thickness distribution through processing.

Background technology

Slit-lamp is the important instrument of eye examination, and slit-lamp microscope is by illuminator and binocular microscope group Becoming, it can not only make the pathology that table is shallow observe fully aware of, and can regulate focus and light source width, Make " optic section ", make the pathology of deep tissue also can clearly manifest.Slit-lamp can clearly be seen Examine before eyelid, conjunctiva, sclera, cornea anterior chamber, iris, pupil, crystalline lens and vitreum 1/3, can be true Determine the position of pathology, character, size and the degree of depth thereof.Cornea be in eyeball antetheca transparent membrane, about Account for front the 1/6 of tunica fibrosa, see that cornea is circular from behind, horizontal oval from being above seen as.Cornea has Dioptric and self-protection function, be in critical role in whole eyes；Therefore thickness and the song of cornea are studied Rate distribution facilitates deciding on whether cornea occurs pathology.But in the prior art, the most do not occur that utilization is split The curvature distribution of gap lamp measurement cornea and the technical scheme of thickness distribution, therefore, in this sense, if Slit-lamp can be utilized to realize measuring curvature distribution and the thickness distribution of cornea, the most necessarily expanded the use of slit-lamp On the way.

Summary of the invention

The invention discloses and a kind of utilize slit-lamp to survey corneal curvature and the way of thickness, its object is to utilization and split The cornea tangent plane crack figure obtained, to eye cornea tangent plane imaging, is processed into cornea sectional drawing, then by gap lamp Curvature distribution and the thickness distribution of cornea is tried to achieve according to cornea sectional drawing.

Technical scheme:

A kind of utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution, comprise the steps:

Slit-lamp system illumination light path, just to human eye to be measured, makes slit of illumination illuminate the cornea tangent plane along its primary optical axis； Slit-lamp system imaging light path is to have angle the direction of β to described angle with described slit-lamp system illumination light path The crack imaging of film tangent plane, obtains cornea tangent plane crack figure；

Described cornea tangent plane crack figure is projected to cornea tangent plane, obtains cornea sectional drawing, cut from described cornea Identify anterior surface of cornea profile and posterior surface of cornea profile on the figure of face, record curvature distribution and the thickness of cornea Distribution.

Further, described cornea tangent plane crack figure is projected to cornea tangent plane, obtains cornea sectional drawing, from Identify anterior surface of cornea profile and posterior surface of cornea profile on described cornea sectional drawing, record the curvature of cornea Distribution and thickness distribution, specifically include following steps:

Certain pixel EcXi` on the figure of described cornea tangent plane crack is projected to the correspondence on described cornea tangent plane Point EcXi, and calculate described corresponding points EcXi true coordinate on described cornea tangent plane；

Remaining each pixel on the figure of described cornea tangent plane crack is projected to described angle the most respectively Correspondence position calculate the true coordinate on cornea tangent plane on film tangent plane；

According to the true coordinate of the whole pixels projected on described cornea tangent plane, obtain described cornea Sectional drawing, after being processed by described cornea sectional drawing, identifies front surface profile and the rear surface profile of cornea, Record curvature distribution and the thickness distribution of cornea.

Further, described certain pixel EcXi` on the figure of cornea tangent plane crack is projected to described cornea cut Corresponding points EcXi on face, and calculate described corresponding points EcXi true coordinate on described cornea tangent plane, Specifically include following steps:

The imaging width defining described cornea tangent plane crack figure is L, and the total number of pixel in picture traverse direction is K, the center line of described cornea tangent plane crack figure is Sx`, described certain some EcXi` and described center line Sx` it Between number of pixels be ki, the confocal point of described imaging optical path and described illumination path is Sx；

Obtain the space length Xi between described certain some EcXi` and described center line Sx`:

$\mathrm{Xi}=\frac{\mathrm{ki}}{K}L;$

Obtain described confocal some Sx distance SxEcXi to described corresponding points EcXi:

$\mathrm{SxEcXi}=\frac{\mathrm{SxEcX}{i}^{\′}}{\sin \mathrm{\β}}=\frac{\mathrm{Xi}}{\sin \mathrm{\β}}=\frac{\mathrm{ki}\·L}{K\·\sin \mathrm{\β}};$

With described confocal some Sx as initial point, the limit at described SxEcXi place is that abscissa sets up coordinate system, asks Go out the coordinate of described corresponding points EcXi

Wherein, SxEcXi` is the described confocal some Sx distance to described certain pixel EcXi`, and its value is Xi.

Further, the primary optical axis of described slit-lamp system imaging light path and described slit-lamp system illumination light path The plane that constitutes of primary optical axis respectively with plane and the described cornea tangent plane at figure place, described cornea tangent plane crack Vertically；The plane at figure place, described cornea tangent plane crack and the intersection of described cornea tangent plane are described center line Rotating coaxial line corresponding to Sx`.

Further, described slit-lamp system imaging light path and described slit-lamp illumination path, with described in Coaxial line corresponding to heart line Sx` is rotary shaft, rotates in the same plane, described slit-lamp system imaging Light path can be to different cornea tangent plane imagings.

Further, the plane at figure place, described cornea tangent plane crack and the angle of described cornea tangent plane composition are (90°-β)。

Further, described angle β is read by angle scale or the automatic or hand by Angle Measurement Module Move and record.

Further, before making described slit-lamp system imaging light path to the imaging of eye cornea crack, in addition it is also necessary to Regulation slit-lamp, step is:

Regulate the probe of slit-lamp up and down, make the primary optical axis pair of described slit-lamp system illumination light path Quasi-corneal vertex Ec；

Front and back regulate described probe, make described slit-lamp system imaging light path corneal blur-free imaging；

Now, corneal vertex Ec is in the vicinity of described confocal some Sx.

A kind of utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution, comprise the steps:

Slit-lamp system illumination light path, just to human eye to be measured, makes slit of illumination illuminate the cornea tangent plane along its primary optical axis； Slit-lamp system imaging light path is to have angle the direction of β to described angle with described slit-lamp system illumination light path The crack imaging of film tangent plane, obtains cornea tangent plane crack figure；

Described cornea tangent plane crack figure identifies anterior surface of cornea profile and posterior surface of cornea profile, then Projecting to, with by cornea tangent plane crack figure, the projecting method that cornea tangent plane is same, the forward and backward surface of corneal is taken turns Exterior feature carries out coordinate transform, obtains the forward and backward surface outline curves of the cornea on cornea tangent plane, and then records described The curvature distribution of cornea and thickness distribution.

Beneficial effects of the present invention: the present invention includes two kinds of technical schemes, Yi Zhongshi: by being adopted by slit-lamp Collect to cornea tangent plane crack figure on all pixels through projection process, obtained cornea sectional drawing, so Afterwards according to cornea sectional drawing, find anterior surface of cornea profile and posterior surface of cornea profile, record the thickness of cornea Distribution and curvature distribution.Another is: first find out on the cornea tangent plane crack figure that slit-lamp shooting obtains Anterior surface of cornea profile and posterior surface of cornea profile, then use and in scheme one by the figure of cornea tangent plane crack Pixel projects to projection thinking same on cornea tangent plane, and above-mentioned cornea front and rear surfaces profile is carried out coordinate Conversion, obtains the cornea front and rear surfaces contour curve on cornea tangent plane, and then the curvature recording described cornea is divided Cloth and thickness distribution.The method has widened the purposes of slit-lamp, i.e. splits according to the cornea tangent plane that slit-lamp records Gap figure, records curvature distribution and the thickness distribution of cornea after being processed to, help doctor to utilize slit-lamp to detect More fully human eye parameter.

Accompanying drawing explanation

Fig. 1 is the flow chart of the method utilizing slit-lamp angle measurement film curvature distribution and thickness distribution；

Fig. 2 is the exploded view of step S102 in Fig. 1；

Fig. 3 is that slit-lamp surveys eye cornea system schematic；

Fig. 4 is cornea tangent plane crack Fig. 1 that slit-lamp collects, namely in Fig. 5 along A to seeing Detail drawing；

Fig. 5 is the projection signal that cornea tangent plane crack Fig. 1 that slit-lamp collects projects to cornea tangent plane 3 Figure；

Fig. 6 is that the coordinate that picture point EcXi` on cornea tangent plane crack Fig. 1 projects on cornea tangent plane 3 calculates Schematic diagram.

Above-mentioned each figure respectively meets and the title of correspondence is respectively as follows:

1. the cornea tangent plane crack figure that slit-lamp collects；

2. the primary optical axis of slit-lamp system illumination light path 101 and the primary optical axis of slit-lamp system imaging light path 102 The plane constituted；

3. the cornea tangent plane that slit-lamp system illumination light path 101 illuminates along its primary optical axis, and cornea sectional drawing weight Close；

E, human eye；

Ec, corneal vertex；

Ec ', the corneal vertex picture point in cornea tangent plane crack Fig. 1；

Ec1`, the anterior surface of cornea picture in cornea tangent plane crack Fig. 1；

Ec2`, the posterior surface of cornea picture in cornea tangent plane crack Fig. 1；

EcXi, collection cornea corresponding to cornea image on certain point；

The point that EcXi`, EcXi are corresponding on cornea tangent plane crack Fig. 1；

The confocal point of Sx, slit-lamp system illumination light path 101 and slit-lamp system imaging light path 102；

Sx`, cornea tangent plane crack figure center line, corresponding slit-lamp system illumination light path 101 and slit-lamp system The common axis of rotation of imaging optical path 102；

Pixel wide between the center line Sx` of ki, EcXi` and cornea tangent plane crack Fig. 1；

The sky representated by pixel wide ki between the center line Sx` of Xi, EcXi` and cornea tangent plane crack Fig. 1 Spacing；

β, slit-lamp system illumination light path 101 and the angle of slit-lamp system imaging light path 102；

L, in cornea tangent plane crack Fig. 1 cross confocal some Sx the width corresponding to image acquisition region；

K, the total number of pixel of cornea tangent plane crack Fig. 1 width；

101, slit-lamp system illumination light path；

102, slit-lamp system imaging light path.

Detailed description of the invention

In order to make the technical problem to be solved, technical scheme and beneficial effect clearer, Below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that this place is retouched The specific embodiment stated only in order to explain the present invention, is not intended to limit the present invention.

With reference to the flow chart that Fig. 1, Fig. 1 are the method utilizing slit-lamp angle measurement film curvature distribution and thickness distribution, Including:

S101: slit-lamp system illumination light path, just to human eye to be measured, makes slit of illumination illuminate the angle along its primary optical axis Film tangent plane；Slit-lamp system imaging light path is to have angle the direction of β with described slit-lamp system illumination light path To described cornea tangent plane crack imaging, obtain cornea tangent plane crack figure.

Specifically, with reference to Fig. 3, Fig. 4 and Fig. 5.In figure 3, slit-lamp system illumination light path 101 is the most right Human eye E to be measured, and inject from corneal vertex Ec；Slit-lamp system imaging light path 102 with slit-lamp system Illumination path 101 structure forms an angle the direction of β, the cornea illuminating crack lamp system illumination path 101 Tangent plane imaging, obtains cornea tangent plane crack Fig. 1.In the technical program, slit-lamp system imaging light path 102 Need to meet confocal coaxial condition with slit-lamp system illumination light path 101.So-called confocal, institute the most in figure 3 Slit-lamp system imaging light path 102 and the slit-lamp system illumination light path 101 of display have common focus Sx； So-called coaxial, i.e. slit-lamp system imaging light path 102 and slit-lamp system illumination light path 101 common vertical in Same axis and rotating around this axis.With reference to Fig. 4 and Fig. 5, owing to confocal some Sx is that coaxial line is splitting It is flat that the primary optical axis of gap lamp system illumination path 101 and the primary optical axis of slit-lamp system imaging light path 102 are constituted Projection on face 2, it is understood therefore that cornea tangent plane crack figure center line Sx` is described coaxial line.

S102: described cornea tangent plane crack figure is projected to cornea tangent plane, obtains cornea sectional drawing, and from institute Stating and identify anterior surface of cornea profile and posterior surface of cornea profile on cornea sectional drawing, the curvature recording cornea is divided Cloth and thickness distribution.

Specifically, refer to Fig. 4 and Fig. 5, first the pixel on cornea tangent plane crack Fig. 1 is all projected On cornea tangent plane 3, (not shown, cornea sectional drawing and cornea tangent plane 3 are positioned at same to obtain cornea sectional drawing One plane), from cornea sectional drawing, find anterior surface of cornea profile and posterior surface of cornea profile, then according to angle Film front surface profile and posterior surface of cornea profile obtain corneal curvature distribution and thickness distribution；Specifically, to step The process step of the first situation in rapid S102 is shown in Fig. 2,

S201: certain pixel EcXi` on the figure of described cornea tangent plane crack is projected on described cornea tangent plane Corresponding points EcXi, and calculate described corresponding points EcXi true coordinate on described cornea tangent plane.

For step S201 specifically launch explanation, refer to Fig. 4, Fig. 5 and Fig. 6.Please refer to Fig. 4, Fig. 4 is the detail drawing of the cornea tangent plane crack Fig. 1 in Fig. 5.In Fig. 4, definition cornea tangent plane crack Fig. 1 exists The total number of pixel on width is K, and width is L, and the center line of cornea tangent plane crack Fig. 1 is Sx`, The certain point on cornea tangent plane crack Fig. 1 gathered is EcXi`, EcXi` and cornea tangent plane crack figure center line Number of pixels between Sx` is ki, and space length is Xi；EcXi` correspondence illuminates along its primary optical axis in slit of illumination The point of cornea tangent plane 3 is EcXi；Anterior surface of cornea image is Ec1`, and posterior surface of cornea picture is Ec2`；Fig. 3 In corneal vertex Ec corresponding as Ec` in the diagram.In order to try to achieve the true picture of cornea tangent plane 3, need The each pixel on cornea tangent plane crack Fig. 1 to be collected by slit-lamp corresponds on cornea tangent plane 3. Therefore, only require out that one of them pixel of cornea tangent plane crack Fig. 1 illuminates along its primary optical axis in slit of illumination Cornea tangent plane 3 on actual position, it is possible to obtain on cornea tangent plane crack Fig. 1 it by same way After image vegetarian refreshments actual position on the cornea tangent plane 3 that slit of illumination illuminates along its primary optical axis, finally according to cornea The image recognition anterior surface of cornea profile of tangent plane and posterior surface of cornea profile, so try to achieve corneal thickness distribution and Curvature distribution.

Please continue to refer to Fig. 4 and Fig. 5, owing to L, K are system given value, thus ki only need to be recorded, just Xi, Xi can be tried to achieve can be tried to achieve by equation below:

$\mathrm{Xi}=\frac{\mathrm{ki}}{K}L.---\left(1\right)$

Refer to Fig. 5, when adopting figure due to slit-lamp imaging, be to being perpendicular to slit-lamp system imaging light path 102 Primary optical axis and through plane (the i.e. plane 1) imaging of confocal some Sx, thus a certain on cornea tangent plane 3 Select picture point EcXi of EcXi ' it is considered to be cornea tangent plane crack Fig. 1 that EcXi collects at slit-lamp On projection.In the technical program, confocal some Sx is slit-lamp system illumination light path 101 and slit-lamp system The common focus of system imaging optical path 102, it is in cornea tangent plane crack Fig. 1, is also at slit-lamp system In the plane 2 that the primary optical axis of illumination path 101 and the primary optical axis of slit-lamp system imaging light path 102 are constituted, Also in cornea tangent plane 3.

With reference to Fig. 4 and Fig. 5, triangle SxEcXiEcXi` know,

$\mathrm{SxEcXi}=\frac{\mathrm{SxEcX}{i}^{\′}}{\sin \mathrm{\β}}=\frac{\mathrm{Xi}}{\sin \mathrm{\β}}=\frac{\mathrm{ki}\·L}{K\·\sin \mathrm{\β}},---\left(2\right)$

Therefore, the distance of SxEcXi can be obtained according to formula (2).

With reference to Fig. 6, after the value of SxEcXi is obtained, with confocal some Sx as the origin of coordinates, with SxEcXi institute Limit be that abscissa sets up coordinate system, obtain the coordinate of EcXi

Again owing to EcXi, EcXi` are with on a plane, at figure image height after therefore EcXi` projection becomes EcXi Spending on direction constant, namely its ordinate is constant.

Therefore, by above-mentioned calculating, can obtain on cornea tangent plane crack Fig. 1 that slit-lamp collects One of them pixel EcXi` is coordinate position on the cornea tangent plane 3 that slit of illumination illuminates along its primary optical axis.

S202: remaining each pixel on the figure of described cornea tangent plane crack is projected to the most respectively Correspondence position calculate true coordinate thereon on described cornea tangent plane.

When the pixel EcXi` obtained on cornea tangent plane crack Fig. 1 that slit-lamp collects is on slit of illumination edge After the actual position on cornea tangent plane 3 that its primary optical axis illuminates, obtain slit-lamp by same way with that The cornea that other pixels on cornea tangent plane crack Fig. 1 collected illuminate along its primary optical axis in slit of illumination True coordinate on tangent plane 3.Similarly, other pixels are constant on picture altitude direction before and after projection, Namely its ordinate is constant.The cornea tangent plane 3 i.e. cornea itself illuminated along its primary optical axis due to slit of illumination Real tangent plane, takes up an official post so can obtain, by this way, cornea tangent plane crack Fig. 1 that slit-lamp collects Meaning some actual position on the cornea tangent plane that slit of illumination illuminates along its primary optical axis.

Step S203: when accurately determining all pixels on cornea tangent plane crack Fig. 1 that slit-lamp collects After selecting the actual position on the cornea tangent plane 3 that slit of illumination illuminates along its illumination path primary optical axis, obtain cornea The true picture of tangent plane.After the true picture of cornea tangent plane is processed, obtain anterior surface of cornea contour images and Rear surface contour images, thus obtain curvature distribution and the thickness distribution of cornea.

The present invention also disclosed another and utilizes slit-lamp angle measurement film curvature distribution and the method for thickness distribution, Comprise the steps:

S301: slit-lamp system illumination light path, just to human eye to be measured, makes slit of illumination illuminate the angle along its primary optical axis Film tangent plane；Slit-lamp system imaging light path is to have angle the direction of β with described slit-lamp system illumination light path To described cornea tangent plane crack imaging, obtain cornea tangent plane crack figure.

S302: identify anterior surface of cornea profile and posterior surface of cornea profile on the figure of described cornea tangent plane crack, Then use and cornea tangent plane crack figure is projected to the projection way that cornea tangent plane is same, the forward and backward table of corneal Facial contour carries out coordinate transform, obtains the forward and backward surface outline curves of the cornea on cornea tangent plane, and then records The curvature distribution of described cornea and thickness distribution.

Step S301 is the same with step S101, is not repeated at this.

For step S302, refer to Fig. 4.According to the cornea tangent plane crack Fig. 1 having been taken by, at it Above-identified go out anterior surface of cornea profile Ec1` and posterior surface of cornea profile Ec2`. with reference to Fig. 5, then by angle Film front surface profile Ec1` and each pixel of posterior surface of cornea profile Ec2`, successively with and formula (1) and The changes in coordinates thinking that formula (2) is same, after each pixel of anterior surface of cornea profile Ec1` and cornea Each pixel of surface profile Ec2` projects to, on cornea tangent plane 3, obtain the angle on cornea tangent plane 3 respectively The forward and backward surface outline curves of film (not shown), finally tries to achieve corneal curvature distribution and thickness distribution.Therefore, The method need not to remove anterior surface of cornea profile Ec1` and posterior surface of cornea profile on cornea tangent plane crack Fig. 1 Rest of pixels point beyond Ec2` carries out projection transform, operates more succinct.

In two kinds of technical schemes, slit-lamp system illumination light path 101 and slit-lamp system imaging light path 102 Can rotate around coaxial line Sx`, slit of illumination can change along the position of the cornea tangent plane 3 that its primary optical axis illuminates, Therefore slit-lamp system imaging light path 102 can be to the cornea tangent plane crack imaging of diverse location.Then with above-mentioned Two kinds of methods, record thickness distribution and the curvature distribution of cornea diverse location by cornea sectional drawing.

By Fig. 5 it can also be seen that slit-lamp system illumination light path 101 generates slit of illumination illuminates along its primary optical axis Cornea tangent plane 3, the primary optical axis of slit-lamp system illumination light path 101 and slit-lamp system imaging light path 102 Plane 2 and cornea tangent plane 3 that primary optical axis is constituted are vertical, and the intersection of cornea tangent plane 3 and plane 2 is crack The primary optical axis of lamp system illumination path 101.

With reference to Fig. 5, slit-lamp system imaging light path 102 primary optical axis is perpendicular to the cornea that slit-lamp collects Tangent plane crack Fig. 1, the angle of slit-lamp system illumination light path 101 and slit-lamp system imaging light path 102 is β.Owing to the center line Sx` of cornea tangent plane crack Fig. 1 is perpendicular to plane 2, slit-lamp system illumination light path The primary optical axis of 101 is positioned at plane 2, then center line Sx` is necessarily perpendicular to slit-lamp system illumination light path 101； Meanwhile, center line Sx` is perpendicular to the straight line that SxEcXi ' is constituted, the folder that therefore angle EcXiSxEcXi` is constituted Angle is cornea tangent plane crack Fig. 1 and the angle of cornea tangent plane 3 composition, and its value is (90 ° of-β).Cornea The intersection of tangent plane crack Fig. 1 and cornea tangent plane 3 is center line Sx`.

It addition, slit-lamp needs to meet slit-lamp system imaging light path 102 and crack on Design of Mechanical Structure Lamp system illumination path 101 can rotate around same rotary shaft, and this rotary shaft is perpendicular to slit-lamp system imaging light The plane 2 that road 102 and slit-lamp system illumination light path 101 are constituted, its intersection point is confocal some Sx.Pass through Fig. 5 It can be seen that this rotary shaft is center line Sx`, because line Sx` is in plane 2 centered by confocal some Sx Projection.

Also, it should be noted before utilizing the imaging optical path of slit-lamp to the imaging of eye cornea crack, in addition it is also necessary to Regulation slit-lamp, its regulating step is:

With reference to Fig. 1, by the probe (not shown) of upper and lower, left and right four direction regulation slit-lamp, make Primary optical axis alignment corneal vertex Ec of slit-lamp system illumination light path 101；Regulate spy the most in the longitudinal direction Head, until slit-lamp system imaging light path 102 can corneal blur-free imaging.Now, corneal vertex Ec is in The vicinity of slit-lamp system illumination light path 101 and confocal some Sx of slit-lamp system imaging light path 102.

It addition, in two schemes, angle β can pass through angle scale (not shown) read or according to angle Degree measurement module (not shown) automatic or manual records.

In sum, in the present invention, a kind of scheme is: split by the cornea tangent plane photographed by slit-lamp Whole pixels on gap figure project to cornea tangent plane, have obtained cornea sectional drawing, then according to cornea tangent plane Figure, finds anterior surface of cornea profile and posterior surface of cornea profile, according to table after anterior surface of cornea profile and cornea Facial contour records thickness distribution and the curvature distribution of cornea；Another kind of scheme is: first obtain in slit-lamp shooting Cornea tangent plane crack figure on find anterior surface of cornea profile and posterior surface of cornea profile, then utilize and first The coordinate projection thinking that the scheme of kind is same, the forward and backward surface profile of cornea on the figure of corneal tangent plane crack is carried out Coordinate transform, obtains they contour curves on cornea tangent plane respectively, records cornea according to this contour curve Thickness distribution and curvature distribution.Both approaches, has widened the purposes of slit-lamp, helps doctor to detect more Comprehensively human eye parameter.

The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all at this Any amendment, equivalent and the improvement etc. made within bright spirit and principle, should be included in the present invention Protection domain within.

Claims (9)

1. one kind utilizes slit-lamp angle measurement film curvature distribution and the method for thickness distribution, it is characterised in that include Following steps:

Slit-lamp system illumination light path, just to human eye to be measured, makes slit of illumination illuminate the cornea tangent plane along its primary optical axis； Slit-lamp system imaging light path is to have angle the direction of β to described angle with described slit-lamp system illumination light path The crack imaging of film tangent plane, obtains cornea tangent plane crack figure；

Described cornea tangent plane crack figure is projected to cornea tangent plane, obtains cornea sectional drawing, cut from described cornea Identify anterior surface of cornea profile and posterior surface of cornea profile on the figure of face, record curvature distribution and the thickness of cornea Distribution.

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution the most as claimed in claim 1, its It is characterised by, described cornea tangent plane crack figure is projected to cornea tangent plane, obtains cornea sectional drawing, from described Identify anterior surface of cornea profile and posterior surface of cornea profile on cornea sectional drawing, record the curvature distribution of cornea And thickness distribution, specifically include following steps:

Certain pixel EcXi` on the figure of described cornea tangent plane crack is projected to the correspondence on described cornea tangent plane Point EcXi, and calculate described corresponding points EcXi true coordinate on described cornea tangent plane；

Remaining each pixel on the figure of described cornea tangent plane crack is projected to described angle the most respectively Correspondence position calculate the true coordinate on cornea tangent plane on film tangent plane；

According to the true coordinate of the whole pixels projected on described cornea tangent plane, obtain described cornea Sectional drawing, after being processed by described cornea sectional drawing, identifies front surface profile and the rear surface profile of cornea, Record curvature distribution and the thickness distribution of cornea.

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution the most as claimed in claim 2, its It is characterised by: described certain pixel EcXi` on the figure of cornea tangent plane crack is projected on described cornea tangent plane Corresponding points EcXi, and calculate described corresponding points EcXi true coordinate on described cornea tangent plane, tool Body comprises the steps:

The imaging width defining described cornea tangent plane crack figure is L, and the total number of pixel in picture traverse direction is K, the center line of described cornea tangent plane crack figure is Sx`, described certain pixel EcXi` and described center line Sx` Between number of pixels be ki, the confocal point of described imaging optical path and described illumination path is Sx；

Obtain described space length Xi between certain pixel EcXi` and described center line Sx`:

$Xi=\frac{ki}{K}\×L;$

Obtain described confocal some Sx distance SxEcXi to described corresponding points EcXi:

$SxEcXi=\frac{{\mathrm{SxEcXi}}^{\′}}{sin\mathrm{\β}}=\frac{Xi}{\sin \mathrm{\β}}=\frac{ki\×L}{K\×sin\mathrm{\β}};$

With described confocal some Sx as initial point, the limit at described SxEcXi place is that abscissa sets up coordinate system, asks Go out the coordinate of described corresponding points EcXi

Wherein, SxEcXi` is the described confocal some Sx distance to described certain pixel EcXi`, and its value is Xi.

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution the most as claimed in claim 3, its It is characterised by: the primary optical axis of described slit-lamp system imaging light path and the master of described slit-lamp system illumination light path The plane that optical axis is constituted is vertical with the plane at figure place, described cornea tangent plane crack and described cornea tangent plane respectively Directly；The plane at figure place, described cornea tangent plane crack and the intersection of described cornea tangent plane are described center line Sx` Corresponding rotating coaxial line.

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution the most as claimed in claim 4, its Be characterised by: described slit-lamp system imaging light path and described slit-lamp system illumination light path, with described in Coaxial line corresponding to heart line Sx` is rotary shaft, rotates in the same plane, described slit-lamp system imaging Light path can be to different cornea tangent plane imagings.

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution the most as claimed in claim 4, its It is characterised by: the angle that the plane at figure place, described cornea tangent plane crack and described cornea tangent plane are constituted is (90 ° -β)。

7. utilize slit-lamp angle measurement film curvature distribution and thickness as according to any one of claim 3 to 6 divide The method of cloth, it is characterised in that: described angle β is read by angle scale or passes through Angle Measurement Module Automatic or manual records.

Utilize slit-lamp angle measurement film curvature distribution and the method for thickness distribution the most as claimed in claim 7, its It is characterised by: before making described slit-lamp system imaging light path to the imaging of eye cornea crack, in addition it is also necessary to regulation Slit-lamp, step is:

Regulate the probe of slit-lamp up and down, make the primary optical axis alignment angle of described slit-lamp system illumination light path Film summit Ec；

Front and back regulate described probe, make described slit-lamp system imaging light path corneal blur-free imaging；

Now, corneal vertex Ec is in the vicinity of described confocal some Sx.

9. one kind utilizes slit-lamp angle measurement film curvature distribution and the method for thickness distribution, it is characterised in that include Following steps:

Slit-lamp system illumination light path, just to human eye to be measured, makes slit of illumination illuminate the cornea tangent plane along its primary optical axis； Slit-lamp system imaging light path is to have angle the direction of β to described angle with described slit-lamp system illumination light path The crack imaging of film tangent plane, obtains cornea tangent plane crack figure；

Described cornea tangent plane crack figure identifies anterior surface of cornea profile and posterior surface of cornea profile, then Projecting to, with by cornea tangent plane crack figure, the projecting method that cornea tangent plane is same, the forward and backward surface of corneal is taken turns Exterior feature carries out coordinate transform, obtains the forward and backward surface outline curves of the cornea on cornea tangent plane, and then records described The curvature distribution of cornea and thickness distribution.