CN1112004A - Spray for treating cold and sore-throat and its preparing method - Google Patents
Spray for treating cold and sore-throat and its preparing method Download PDFInfo
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- CN1112004A CN1112004A CN 94115091 CN94115091A CN1112004A CN 1112004 A CN1112004 A CN 1112004A CN 94115091 CN94115091 CN 94115091 CN 94115091 A CN94115091 A CN 94115091A CN 1112004 A CN1112004 A CN 1112004A
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Abstract
The spray for curing cold and upper respiratory tract disease with obvious curative effect is prepared from 7 Chinese-medicinal materials including honeysuckle flower, forsythia fruit, subprostrate sophora root, belamcanda rhizome, magnolia bark, etc. and others through preparing Chinese-medicinal extract and mixing it with alcohol, distilled water and sodium benzoate and features no toxic by-effect.
Description
What the present invention relates to is a kind of medicine for the treatment of diseases caused by exogenous pathogenic factor and upper respiratory tract illness and produces its method.
Flu is that a kind of regular incidence, frequently-occurring disease, sickness rate are up to more than 25%, clinically except that features such as nasal obstruction, watery nasal discharge, sneeze, cough, headache, aversion to cold, heating, general malaise are arranged, and the normal symptoms such as rhinitis, sinusitis, upper respiratory tract infection that cause.Generally adopt oral at present or the injection Pharmaceuticals is treated, the one, all there is certain toxic and side effects in chemicals, and the 2nd, curative effect is relatively poor, takes sometimes to take orally, the multiple medicine of external starts at the same time, also is difficult to prove effective.
The objective of the invention is to avoid the deficiencies in the prior art, and a kind of inner disease outer treat, good effect are provided, without any side effects drives sense sore-throat relieving spray product and produces its method.
Can take following technical scheme to realize purpose.Extractum with Chinese herbal medicine Flos Lonicerae, Fructus Forsythiae, Radix Sophorae Tonkinensis, Rhizoma Belamcandae, Cortex Magnoliae Officinalis, Radix Platycodonis, Herba Menthae is active ingredient, and the additive preparing of forming with ethanol, distilled water, sodium benzoate forms.After earlier the medium-height grass medicinal alcohol being extracted respectively as solvent when producing, promptly get the sense sore-throat relieving spray that drives of the present invention with ethanol, distilled water, sodium benzoate mixing preparation again.
Be described in further detail in conjunction with the content of embodiment the technical program.
Both can adopt their primary crude drug to Flos Lonicerae, Fructus Forsythiae, Radix Sophorae Tonkinensis, Rhizoma Belamcandae, Cortex Magnoliae Officinalis, a few flavor Chinese herbal medicine of Radix Platycodonis, also can adopt commercially available decoction pieces through processing; Equally, can adopt primary crude drug, also can directly adopt the Mentholum that therefrom extracts Herba Menthae.The pattern of medical material is to driving the not influence of drug effect of sense sore-throat relieving spray, and just technical process is complicated and simple, adopts decoction pieces, Mentholum then can make technology simple.Their consumption can be selected by conventional the taking the circumstances into consideration of the traditional Chinese medical science.Additives are made up of ethanol, distilled water and sodium benzoate, the effect of ethanol, distilled water is as the solvent of Chinese herbal medicine active ingredient, diluent, benzene toluene sodium is as the antiseptic of herb liquid, and selected concentration of ethanol does not have influence to the effectiveness of driving sense sore-throat relieving spray.The proportionate relationship of Chinese herbal medicine active ingredient and additives consumption, promptly dilute strength also can be handled routinely.
During preparation, should earlier the medium-height grass medicinal alcohol be extracted active ingredient respectively as solvent, make extractum after, evenly promptly get preparation of the present invention with the additives mixing preparation again.
Drive in the sense sore-throat relieving spray, their consumption is pressed the spray total weight:
Flos Lonicerae 9.75-10.25%, Fructus Forsythiae 4.25-4.75%,
Radix Sophorae Tonkinensis 2.75-3.25%, Rhizoma Belamcandae 2.25-2.75%,
Cortex Magnoliae Officinalis 2.25-2.75%, Radix Platycodonis 1.25-1.75%,
Mentholum 0.05-0.25%,
Dehydrated alcohol 10-14%, distilled water 64-85%,
Benzoic acid steel 0.5-1%.
And be prepared in the following manner:
When 1, extracting Flos Lonicerae, Fructus Forsythiae medicinal liquid, press crude drug weight and add doubly 95% alcohol solvent of 5-6, just soak four hours post-heating in advance, extract three times, extracted 40 minutes at every turn.Filtrate with three extractions makes alcohol reflux be condensed into fluid extract under 80 ℃, and fluid extract proportion 1.15-1.20 is standby.
When extracting Rhizoma Belamcandae, Cortex Magnoliae Officinalis medicinal liquid, press crude drug weight and add doubly 95% alcohol solvent of 3-4, soak four hours post-heating, extract three times, each 40 minutes, the filtrate with three extractions made alcohol reflux be condensed into fluid extract under 80 ℃, and proportion 1.15-1.20 is standby.
When extracting Radix Sophorae Tonkinensis, withered stalk medicinal liquid, press crude drug weight and add doubly 95% alcohol solvent of 2-3, soak four hours post-heating, extract each 40 minutes three times.Filtrate with three extractions makes alcohol reflux be condensed into fluid extract under 80 ℃, and proportion 1.15-1.20 is standby.
The Mentholum crystalline solid, it is an amount of to add 95% ethanol, dissolves with crystal to be as the criterion, standby.
Ethanol is poured in the distilled water, and mixing is made and is contained pure distilled water.
2, the fluid extract that last process extracted is concerned in proportion that mix homogeneously adds while stirring then and contains pure distilled water; Place after 24 hours, select for use 201 type quantitative filter papers to filter fast, add again in the filtrate sodium benzoate mixing required preparation.
By the preparation that this proportionate relationship and mode was mixed with, result of use the best.
Example: by above best mode, as solvent, extract the extractum of each Chinese herbal medicine respectively with ethanol, with extractum:
Flos Lonicerae 9.75%, Fructus Forsythiae 4.25%,
Radix Sophorae Tonkinensis 2.75%, Rhizoma Belamcandae 2.25%,
Cortex Magnoliae Officinalis 2.25%, Radix Platycodonis 1.25%,
Mentholum 0.05% mix homogeneously adds then while stirring:
Dehydrated alcohol 10%, the solvent of distilled water 66.95% was placed after 24 hours, selected the low filtration fast of the quantitative filter of 201 types for use, added 0.5% sodium benzoate mix homogeneously in the filtrate again, and the sore-throat relieving spray is felt in driving of obtaining.
Or with extractum:
Flos Lonicerae 10.25%, Fructus Forsythiae 4.75%,
Radix Sophorae Tonkinensis 3.25%, Rhizoma Belamcandae 2.75%,
Cortex Magnoliae Officinalis 2.75%, Radix Platycodonis 1.75%,
Mentholum 0.25%, with dehydrated alcohol 14%,
Distilled water 59.25%, the preparation that sodium benzoate 1% mix homogeneously obtains.All has optimum curative effect.
The sense sore-throat relieving spray of making by the technical program that drives has following advantage:
1, pure Chinese medicinal preparation has no side effect to human body, and non-corrosiveness is free from environmental pollution, and is safe and reliable.
2, prevention and treatment diseases caused by exogenous pathogenic factor and the pharyngeal illness effect of complication mouth and nose thereof are remarkable, and be strong to various bacteria and influenza virus sterilizing power, is a kind of active drug of inner disease outer treat;
3, efficacy stability deposits that drug effect does not subtract more than 2 years.
Claims (4)
1, a kind of sense sore-throat relieving spray that drives, it is characterized in that: it is that extractum with Chinese herbal medicine Flos Lonicerae, Fructus Forsythiae, Radix Sophorae Tonkinensis, Rhizoma Belamcandae, Cortex Magnoliae Officinalis, Radix Platycodonis, Herba Menthae is active ingredient, the goods that the additives mixing preparation of forming with ethanol, distilled water, sodium benzoate forms.
2, a kind of described sense sore-throat relieving spray preparing process of driving of claim 1 that is used for is characterized in that: after it extracts the medium-height grass medicinal alcohol respectively as solvent earlier, again with ethanol, distilled water, sodium benzoate additives mixing preparation.
3, the sense sore-throat relieving spray that drives as claimed in claim 1 is characterized in that: their consumption, press the spray total weight:
Flos Lonicerae 9.75-10.25%, Fructus Forsythiae 4.25-4.75%,
Radix Sophorae Tonkinensis 2.75-3.25%, Rhizoma Belamcandae 2.25-2.75%,
Cortex Magnoliae Officinalis 2.25-2.75%, Radix Platycodonis 1.25-1.75%,
Mentholum 0.05-0.25%,
Dehydrated alcohol 10-14%, distilled water 64-85%,
Benzoic acid steel 0.5-1%.
4, preparation method as claimed in claim 2 is characterized in that:
When a, extraction Flos Lonicerae, Fructus Forsythiae medicinal liquid, press crude drug weight and add doubly 95% alcohol solvent of 5-6, just soak four hours post-heating in advance, extract three times, extracted 40 minutes at every turn, the filtrate with three extractions makes alcohol reflux be condensed into fluid extract under 80 ℃, and is standby;
When extracting Rhizoma Belamcandae, Cortex Magnoliae Officinalis medicinal liquid, press crude drug weight and add doubly 95% alcohol solvent of 3-4, soak four hours post-heating, extract three times, each 40 minutes, the filtrate with three extractions makes alcohol reflux be condensed into fluid extract under 80 ℃, and was standby;
When extracting Radix Sophorae Tonkinensis, Radix Platycodonis medicinal liquid, press crude drug weight and add doubly 95% alcohol solvent of 2-3, soak four hours post-heating, extract three times, each 40 minutes, the filtrate with three extractions makes alcohol reflux be condensed into fluid extract under 80 ℃, and was standby;
With the Mentholum crystalline solid, it is an amount of to add 95% ethanol, dissolves to crystal to be as the criterion, standby;
B, the fluid extract that last process extracted is concerned mix homogeneously in proportion, add while stirring then and contain pure distilled water; Place after 24 hours, select for use 201 type quantitative filter papers to filter fast; In filtrate, add the sodium benzoate mixing, required preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94115091 CN1112004A (en) | 1994-08-26 | 1994-08-26 | Spray for treating cold and sore-throat and its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94115091 CN1112004A (en) | 1994-08-26 | 1994-08-26 | Spray for treating cold and sore-throat and its preparing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1112004A true CN1112004A (en) | 1995-11-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 94115091 Pending CN1112004A (en) | 1994-08-26 | 1994-08-26 | Spray for treating cold and sore-throat and its preparing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1112004A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055410C (en) * | 1997-05-26 | 2000-08-16 | 朱进忠 | Medicine for curing acute tonsillitis and upper respiratory tract infection and its preparing method |
| JP2008517999A (en) * | 2004-10-27 | 2008-05-29 | エスケー ケミカルズ カンパニー リミテッド | Bitter extract useful for prevention and treatment of respiratory diseases |
-
1994
- 1994-08-26 CN CN 94115091 patent/CN1112004A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055410C (en) * | 1997-05-26 | 2000-08-16 | 朱进忠 | Medicine for curing acute tonsillitis and upper respiratory tract infection and its preparing method |
| JP2008517999A (en) * | 2004-10-27 | 2008-05-29 | エスケー ケミカルズ カンパニー リミテッド | Bitter extract useful for prevention and treatment of respiratory diseases |
| EP1811940A4 (en) * | 2004-10-27 | 2009-12-02 | Sk Chemicals Co Ltd | Sophorae subprostratae radix extract for prevention and treatment of respiratory diseases |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |