CN111165473A - Water-soluble film-coated medicament and preparation method thereof - Google Patents
Water-soluble film-coated medicament and preparation method thereof Download PDFInfo
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- CN111165473A CN111165473A CN202010000074.0A CN202010000074A CN111165473A CN 111165473 A CN111165473 A CN 111165473A CN 202010000074 A CN202010000074 A CN 202010000074A CN 111165473 A CN111165473 A CN 111165473A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N27/00—Biocides, pest repellants or attractants, or plant growth regulators containing hydrocarbons
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds
- A01N33/18—Nitro compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds
- A01N33/18—Nitro compounds
- A01N33/20—Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group
- A01N33/22—Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group having at least one oxygen or sulfur atom and at least one nitro group directly attached to the same aromatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/22—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof the nitrogen atom being directly attached to an aromatic ring system, e.g. anilides
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/26—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
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Abstract
The invention discloses a water-soluble film medicament and a preparation method thereof, wherein the water-soluble film medicament comprises a raw material agent and a water-soluble film, the raw material agent is wrapped in the water-soluble film, and the thickness of the water-soluble film is 50-80 um; the raw material agent comprises raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine comprises oxadiazon, butachlor, oxyfluorfen, propine, pretilachlor, clomazone, pendimethalin and oxadiazon; the emulsifier comprises castor oil polyoxyethylene ether, calcium dodecylbenzene sulfonate and triphenylethylene phenol polyoxyethylene ether; the solvent is solvent oil. The invention adopts a bag-in-bag mode, the production process is simple and convenient, the packaging material is pollution-free, the water-soluble film bag wrapped on the medicine has no residue after being dissolved in water, and the medicine is uniformly diffused after being dissolved in water, thereby preventing the local medicine concentration from being overhigh and generating phytotoxicity on local crops, directly acting on the vital crops, avoiding the influence on other crops which normally grow, and simultaneously reducing the harm of the medicine diffused in the air to human bodies.
Description
Technical Field
The invention belongs to the technical field of water-soluble film-covering agents, and particularly relates to a water-soluble film-covering agent and a preparation method thereof.
Background
With the continuous development of science and technology, industrial pesticides refer to chemical agents for preventing and treating plant diseases and insect pests and regulating plant growth in modern agricultural production. It is widely used in agriculture, forestry and animal husbandry production, environment and household sanitation, pest and disease control, and industrial product mildew and moth prevention.
But the abandonment of pesticide package becomes the non-negligible agricultural ecological pollution for human beings and becomes more serious. The residual pesticide in pesticide package has potential harm, and can cause difficult degradation in soil and influence the root growth of plants. And to traditional artifical manual spraying, its work efficiency is low, the mode that machinery sprayed has improved work efficiency greatly, but most medicines are atomized in the air, flow along with the air is scattered everywhere, the overwhelming majority medicine does not directly act on crops itself, adopt iterative machinery to spray the mode, it is big not through increasing economic benefits, and the too big pesticide of concentration is atomized in the air, not only influence peripheral other crop growth, also can influence near resident's healthy simultaneously.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a water-soluble film-coated medicament and a preparation method thereof, which solve the problems that the traditional pesticide spraying mode in the prior art is low in working efficiency and influences the surrounding environment.
The purpose of the invention can be realized by the following technical scheme:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, and the thickness of the water-soluble film is 50-80 um;
the raw material agent comprises raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine comprises oxadiazon, butachlor, oxyfluorfen, propine, pretilachlor, clomazone, pendimethalin and oxadiazon; the emulsifier comprises castor oil polyoxyethylene ether, calcium dodecyl benzene sulfonate and triphenylethylene phenol polyoxyethylene ether; the solvent is solvent oil;
furthermore, the raw material liquid medicine comprises, by mass, 0-12% of oxadiazon, 0-55% of butachlor, 0-2% of propiolic acid, 0-30% of pretilachlor, 0-7% of oxyfluorfen, 0-30% of pendimethalin and 0-12% of clomazone.
Furthermore, the emulsifier comprises 0-6% of castor oil polyoxyethylene ether, 2-6% of calcium dodecyl benzene sulfonate and 0-8% of triphenylethylene phenol polyoxyethylene ether by mass.
Furthermore, the solvent oil of the solvent adopts low-naphthalene solvent oil.
A preparation method of a water-soluble film-coated medicament comprises the following steps:
1) mixing and stirring the raw material liquid medicine, the emulsion and the solvent oil according to the mass ratio of the components, and placing the stirred mixture into a preparation kettle;
2) detecting the raw material mixture of the preparation kettle, returning unqualified products to the preparation kettle again for mixing, standing qualified products, and filtering for later use;
3) and (4) packaging the product subjected to standing filtration by adopting a heat sealing mode through a water-soluble film, carrying out secondary detection, and warehousing after the product is qualified.
Further, the stirring conditions in the step 1) are as follows: the stirring speed is 132r/min, the stirring temperature is normal temperature, and the stirring time is 1 h.
Further, the quality detection standard adopted in the step 2) is to detect the content of each component, the moisture content, the emulsification degree and the pH value of the raw material in the product.
Furthermore, the size of the water-soluble film adopted in the single water-soluble film medicament is 10-60cm2The usage amount of the raw material agent is 5-50 ml.
Furthermore, the water-soluble film-coated medicament is completely dissolved within 60s under the use condition of a water temperature environment of 20 ℃.
The invention has the beneficial effects that:
1. the invention adopts a bag-in-bag mode, the production process is simple and convenient, the packaging material is pollution-free, the water-soluble film bag wrapped on the medicine has no residue after being dissolved in water, and the medicine is uniformly diffused after being dissolved in water, thereby preventing the local medicine concentration from being too high and causing phytotoxicity to local crops.
2. The pesticide provided by the invention has high utilization rate, does not cause residue in packaged and contained objects, can be thrown into a field by 100% after being dissolved in water, is safe for a pesticide applicator in a use mode, does not need to be directly contacted with the pesticide applicator, can be directly thrown into the field, directly acts on crops with the hazard, avoids influencing other crops with normal growth, and simultaneously reduces the harm of the pesticide spread in the air to human bodies.
3. Compared with the prior art, the water-soluble film-coated medicament has higher solubility and dispersibility in water, ensures that the pesticide can be uniformly dispersed in the water to achieve the effect of preventing and treating the pesticide, and can be completely dissolved in 60s at the water temperature of 20 ℃ without other impurities.
Drawings
In order to more clearly illustrate the embodiments or technical solutions in the prior art of the present invention, the drawings used in the description of the embodiments or prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained based on these drawings without creative efforts.
FIG. 1 is a schematic overall flow diagram of an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 50 microns, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine respectively comprises 12% of butachlor, 2% of oxadiazon and 7% of oxyfluorfen in percentage by mass; the mass percentages of the emulsifier are respectively 6% of castor oil polyoxyethylene ether and 4% of calcium dodecyl benzene sulfonate; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.89 |
| Mass fraction of toluene% | 0.91 |
| Mass fraction of xylene% | 7.8 |
| Mass fraction of ethylbenzene% | 1.1 |
| Mass fraction of methanol% | 4.3 |
| Mass fraction of N, N-dimethylformamide% | 1.2 |
| The mass fraction of naphthalene is% | 0.8 |
Example 2:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 60 mu m, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the weight ratio of the liquid medicine of the raw materials is 10 percent of oxadiargyl; the emulsifier comprises 5% of triphenylethylene phenol polyoxyethylene ether, 3% of dodecylbenzene calcium benzene sulfonate and 4% of castor oil polyoxyethylene ether by mass; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
example 3:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 70 microns, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; 2 percent of propine, 7 percent of pretilachlor and 7 percent of oxyfluorfen in the raw material liquid medicine respectively; the emulsifier respectively comprises 4% of triphenylethylene phenol polyoxyethylene ether, 6% of dodecylbenzene calcium benzene sulfonate and 2% of castor oil polyoxyethylene ether in percentage by mass; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.87 |
| Mass fraction of toluene% | 0.95 |
| Mass fraction of xylene% | 6.3 |
| Mass fraction of ethylbenzene% | 1.6 |
| Mass fraction of methanol% | 3.8 |
| Mass fraction of N, N-dimethylformamide% | 1.6 |
| The mass fraction of naphthalene is% | 0.9 |
Example 4:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 80 microns, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine comprises 10% oxadiazon and 30% pendimethalin in percentage by mass respectively; the emulsifier comprises 7% of triphenylethylene phenol polyoxyethylene ether and 3% of dodecyl benzene calcium sulfonate respectively by mass; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
example 5:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 60 mu m, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the mass percentages of the raw material liquid medicines are respectively 30% of pretilachlor; 12% oxadiazon, 12% clomazone; the emulsifier respectively comprises 4% of triphenylethylene phenol polyoxyethylene ether, 3% of dodecylbenzene calcium benzene sulfonate and 3% of castor oil polyoxyethylene ether in percentage by mass; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.94 |
| Mass fraction of toluene% | 0.88 |
| Mass fraction of xylene% | 6.9 |
| Mass fraction of ethylbenzene% | 1.7 |
| Mass fraction of methanol% | 3.1 |
| Mass fraction of N, N-dimethylformamide% | 1.8 |
| The mass fraction of naphthalene is% | 0.9 |
Example 6:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 60 mu m, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine respectively comprises 10% oxadiazon and 4% oxyfluorfen in mass ratio; the emulsifier comprises 5% of triphenylethylene phenol polyoxyethylene ether and 5% of dodecyl benzene calcium sulfonate respectively by mass; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
example 7:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 50 microns, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine comprises 10% oxadiazon and 50% butachlor in percentage by mass respectively; the mass percentages of the emulsifier are 8% of triphenylethylene phenol polyoxyethylene ether and 3% of dodecylbenzene calcium benzene sulfonate respectively; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.93 |
| Mass fraction of toluene% | 0.93 |
| Mass fraction of xylene% | 6.9 |
| Mass fraction of ethylbenzene% | 1.3 |
| Mass fraction of methanol% | 4.1 |
| Mass fraction of N, N-dimethylformamide% | 1.6 |
| The mass fraction of naphthalene is% | 0.9 |
Example 8:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 60 mu m, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine comprises 11% oxadiazon and 55% butachlor in mass ratio respectively; the emulsifier comprises 7% of triphenylethylene phenol polyoxyethylene ether and 3% of dodecyl benzene calcium sulfonate respectively by mass; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.87 |
| Mass fraction of toluene% | 0.88 |
| Mass fraction of xylene% | 7.5 |
| Mass fraction of ethylbenzene% | 1.6 |
| Mass fraction of methanol% | 3.8 |
| Mass fraction of N, N-dimethylformamide% | 1.6 |
| The mass fraction of naphthalene is% | 0.9 |
Example 9:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 80 microns, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine is 120g/L (mass volume ratio) oxadiazon, and the emulsifier comprises 6% of triphenylethylene phenol polyoxyethylene ether and 4% of dodecyl benzene calcium sulfonate respectively in mass ratio; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.87 |
| Mass fraction of toluene% | 0.88 |
| Mass fraction of xylene% | 6.3 |
| Mass fraction of ethylbenzene% | 1.4 |
| Mass fraction of methanol% | 3.8 |
| Mass fraction of N, N-dimethylformamide% | 1.7 |
| The mass fraction of naphthalene is% | 0.9 |
Example 10:
a water-soluble film-coated medicament comprises a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, the thickness of the water-soluble film is 60 mu m, and the raw material agent comprises a raw material liquid medicine, an emulsifier and a solvent; 26% oxadiazon in the raw material liquid medicine, and 6% triphenylethylene phenol polyoxyethylene ether and 4% calcium dodecyl benzene sulfonate in the emulsifier respectively; the solvent is low-naphthalene solvent oil.
The limit indexes of partial components of the coating pesticide are shown in the following table:
| item | Index (I) |
| The mass fraction of benzene is% | 0.92 |
| Mass fraction of toluene% | 0.86 |
| Mass fraction of xylene% | 6.1 |
| Mass fraction of ethylbenzene% | 1.4 |
| Mass fraction of methanol% | 3.9 |
| Mass fraction of N, N-dimethylformamide% | 1.5 |
| The mass fraction of naphthalene is% | 0.8 |
The preparation method of the water-soluble film-coated medicament comprises the following operation steps:
1) mixing and stirring the raw material liquid medicine, the emulsion and the solvent oil according to the proportion, wherein the stirring conditions are as follows: the stirring speed is 132r/min, the stirring temperature is normal temperature, the stirring time is 1h, and the stirred mixture is placed in a preparation kettle.
2) And (3) carrying out quality detection on the raw material mixture of the preparation kettle, wherein the quality detection comprises the mass content, the moisture content, the emulsification degree and the pH value of each component, standing and filtering the qualified product, and returning the unqualified product to the preparation kettle for mixing.
3) And (4) packaging the product subjected to standing filtration by adopting a heat sealing mode for a water-soluble film, carrying out secondary detection, warehousing after the product is qualified, and packaging and warehousing the non-qualified product.
According to actual needs, the size of the water-soluble film adopted in the single water-soluble film packaging agent is 7 x 5.5cm, and the usage amount of the raw material agent is 10 ml. The water soluble membrane-coated medicament is completely dissolved within 60s under the use condition of water temperature environment of 20 ℃.
The invention adopts a bag-in-bag mode, the production process is simple and convenient, the packaging material is pollution-free, the water-soluble film bag wrapped on the medicine has no residue after being dissolved in water, and the medicine is uniformly diffused after being dissolved in water, thereby preventing the local medicine concentration from being too high and causing phytotoxicity to local crops. Compared with the prior art, the water-soluble film-coated medicament has higher solubility and dispersibility in water, ensures that the pesticide can be uniformly dispersed in the water to achieve the effect of preventing and treating the pesticide, and can be completely dissolved in 60s at the water temperature of 20 ℃ without other impurities.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed.
Claims (9)
1. The water-soluble film-coated medicament is characterized by comprising a raw material agent and a water-soluble film, wherein the raw material agent is coated in the water-soluble film, and the thickness of the water-soluble film is 50-80 um;
the raw material agent comprises raw material liquid medicine, an emulsifier and a solvent; the raw material liquid medicine comprises oxadiazon, butachlor, oxyfluorfen, propine, pretilachlor, clomazone, pendimethalin and oxadiazon; the emulsifier comprises castor oil polyoxyethylene ether, calcium dodecyl benzene sulfonate and triphenylethylene phenol polyoxyethylene ether; the solvent is solvent oil.
2. The water-soluble film-coated medicament as claimed in claim 1, wherein the raw material liquid comprises 0-12% oxadiazon, 0-55% butachlor, 0-2% propine, 0-30% pretilachlor, 0-7% oxyfluorfen, 0-30% pendimethalin and 0-12% clomazone by mass.
3. The water-soluble film-coating agent as claimed in claim 1, wherein the emulsifier comprises 0-6% of castor oil polyoxyethylene ether, 2-6% of calcium dodecylbenzene sulfonate and 0-8% of triphenylethylene phenol polyoxyethylene ether by mass.
4. A water-soluble film package as defined in claim 1, wherein said solvent is a low naphthalene miscella.
5. A process for the preparation of a water-soluble film-forming medicament according to any one of claims 1 to 4, comprising the steps of:
1) mixing and stirring the raw material liquid medicine, the emulsion and the solvent oil according to the mass ratio of the components, and placing the stirred mixture into a preparation kettle;
2) detecting the raw material mixture of the preparation kettle, returning unqualified products to the preparation kettle again for mixing, standing qualified products, and filtering for later use;
3) and (4) packaging the product subjected to standing filtration by adopting a heat sealing mode through a water-soluble film, carrying out secondary detection, and warehousing after the product is qualified.
6. The method for preparing a water-soluble film-coated medicament according to claim 5, wherein the stirring conditions in the step 1) are as follows: the stirring speed is 132r/min, the stirring temperature is normal temperature, and the stirring time is 1 h.
7. The method for preparing a water-soluble film-coated medicament according to claim 5, wherein the quality detection standard adopted in the step 2) is to detect the content of each component, the moisture content, the emulsification degree and the pH value of the raw material in the product.
8. The method for preparing a water-soluble film-coated medicament as claimed in claim 5, wherein the size of the water-soluble film used in the single water-soluble film-coated medicament is 10-60cm2The usage amount of the raw material agent is 5-50 ml.
9. The preparation method of the water-soluble film-coated medicament as claimed in claim 5, wherein the water-soluble film-coated medicament is completely dissolved within 60s under the use condition of water temperature of 20 ℃.
Priority Applications (1)
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|---|---|---|---|
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112471146A (en) * | 2020-10-26 | 2021-03-12 | 华南农业大学 | Environment-friendly pesticide hand polishing agent and preparation method thereof |
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| CN105454224A (en) * | 2016-01-26 | 2016-04-06 | 刘圣泉 | Pesticide applied through unmanned aerial vehicle and preparation method thereof |
| CN107318835A (en) * | 2017-07-18 | 2017-11-07 | 江苏省苏科农化有限责任公司 | A kind of agricultural chemicals coagulates pearl and preparation method thereof |
| CN109964934A (en) * | 2019-04-30 | 2019-07-05 | 江苏艾津农化有限责任公司 | A kind of mixed easily decomposing pesticide EC compound dosage form and preparation method thereof of high-content |
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| CN105454224A (en) * | 2016-01-26 | 2016-04-06 | 刘圣泉 | Pesticide applied through unmanned aerial vehicle and preparation method thereof |
| CN107318835A (en) * | 2017-07-18 | 2017-11-07 | 江苏省苏科农化有限责任公司 | A kind of agricultural chemicals coagulates pearl and preparation method thereof |
| CN109964934A (en) * | 2019-04-30 | 2019-07-05 | 江苏艾津农化有限责任公司 | A kind of mixed easily decomposing pesticide EC compound dosage form and preparation method thereof of high-content |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112471146A (en) * | 2020-10-26 | 2021-03-12 | 华南农业大学 | Environment-friendly pesticide hand polishing agent and preparation method thereof |
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Application publication date: 20200519 |